BioFolD -
                University of Düsseldorf

Resources

The researchers of the BioFolD Unit have developed several web server applications that are currently hosted on servers of the Institute for Mathematical Modeling of Biological Systems, University of Düsseldorf, University of Bologna (Italy) and manatined by other collaborators. In the next months a mirror of these applications will be made available on this server. Currently you can reach these web servers using the following links.

Folding and Stability

I-Mutant1.0 Neural Network based method to predict the sign of free energy change of proteins upon single point mutation.
I-Mutant2.0 Support Vector Machine based method to predict the sign and the value of free energy change of proteins upon single point mutation.
K-Fold Support Vector Machine based method to predict the mechanism and rate of protein folding kinetic.

Mutation and Disease

PhD-SNP Support Vector Machine based method to discriminate between neutral or disease-related single point protein mutations.
Meta-SNP Meta-predictor of disease causing varints that uses the output of PANTHER, PhD-SNP, SIFT and SNAP
WS-SNPs&GO Support Vector Machine method for the detection of disease-related SNPs based on functional information
DrCancer Support Vector Machine based method to predict cancer-causing mutations (Beta version).
ContrastRank Statistical method for the classification of cancer samples using exome sequencing data.

Macromolecular Structure

SARA Method for RNA structure alignment and RNA functional assignment.
SARA-Coffee Method for RNA multiple structure alignment
WebRASP Method for the assessment RNA 3D structures

BioFolD -
   University of Düsseldorf