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Meta-SNP
Meta-predictor of disease causing variants


Sequence File: CTX.seq
Alignment File: CTX.seq.blast
Output File: output.txt





Mutation
PANTHER
PhD-SNP
SIFT
SNAP
Meta-SNP
RI

NA
Neutral
Neutral
Neutral
Neutral
6
 
-
0.291
0.320
0.235
0.194
 
NA
Neutral
Neutral
Neutral
Neutral
7
 
-
0.080
0.380
0.235
0.156
 
NA
Neutral
Neutral
Neutral
Neutral
7
 
-
0.176
0.960
0.135
0.166
 
NA
Neutral
Neutral
Neutral
Neutral
7
 
-
0.279
0.500
0.085
0.159
 



Mutation: WT+POS+NEW
    WT: Residue in wild-type protein
    POS: Residue position
    NEW: New residue after mutation

Prediction:
    Neutral: Neutral variants
    Disease: Disease causing variants

Outputs: Value reported under each prediction
     PANTHER: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    PhD-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    SIFT: Positive Value (If >0.05 mutation is predicted Neutral)
    SNAP: Output normalized between 0 and 1 (If >0.5 mutation is predicted Disease)
    Meta-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)

RI: Reliability Index between 0 and 10.