Meta-SNP - Meta-predictor of disease causing variants

Meta-SNP
Meta-predictor of disease causing variants

Sequence File: QNRB.seq
Alignment File: QNRB.seq.blast
Output File: output.txt


Mutation	PANTHER	PhD-SNP	SIFT	SNAP	Meta-SNP	RI

A125T	NA	Neutral	Neutral	Neutral	Neutral	8
	-	0.124	0.430	0.190	0.125

N148K	NA	Disease	Neutral	Disease	Neutral	1
	-	0.540	0.130	0.550	0.465

Mutation: WT+POS+NEW
    WT: Residue in wild-type protein
    POS: Residue position
    NEW: New residue after mutation

Prediction:
    Neutral: Neutral variants
    Disease: Disease causing variants

Outputs: Value reported under each prediction
     PANTHER: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    PhD-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    SIFT: Positive Value (If >0.05 mutation is predicted Neutral)
    SNAP: Output normalized between 0 and 1 (If >0.5 mutation is predicted Disease)
    Meta-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)

RI: Reliability Index between 0 and 10.