Meta-SNP - Meta-predictor of disease causing variants

Meta-SNP
Meta-predictor of disease causing variants

Sequence File: fileseq.seq
Alignment File: fileseq.seq.blast
Output File: output.txt


Mutation	PANTHER	PhD-SNP	SIFT	SNAP	Meta-SNP	RI

Q105R	NA	Neutral	Neutral	Neutral	Neutral	5
	-	0.302	0.350	0.290	0.243

N193S	NA	Neutral	Disease	Disease	Neutral	7
	-	0.090	0.020	0.585	0.141

Mutation: WT+POS+NEW
    WT: Residue in wild-type protein
    POS: Residue position
    NEW: New residue after mutation

Prediction:
    Neutral: Neutral variants
    Disease: Disease causing variants

Outputs: Value reported under each prediction
     PANTHER: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    PhD-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)
    SIFT: Positive Value (If >0.05 mutation is predicted Neutral)
    SNAP: Output normalized between 0 and 1 (If >0.5 mutation is predicted Disease)
    Meta-SNP: Between 0 and 1. (If >0.5 mutation is predicted Disease)

RI: Reliability Index between 0 and 10.