# Prediction of PhD-SNP method on Apr08 database # Code = Swiss-Prot protein code # Mut = Mutation (WildType+Position+Mutant) # Effect = Mutation Effect reported in Swiss-Prot # Pred = Prediction Code Mut Effect Pred _______________________________ Q5MAI5 F228C Neutral Disease Q5MAI5 S288Y Neutral Disease P11802 R24H Disease Neutral Q5MAI5 R53H Neutral Neutral P11802 N41S Disease Neutral Q00535 E225D Neutral Neutral P11802 R122H Neutral Neutral Q5MAI5 S38P Neutral Neutral P11802 R82Q Neutral Neutral P11802 R24C Disease Disease Q5MAI5 R307C Neutral Disease Q14CA7 V111I Neutral Neutral Q14CA7 Q138H Neutral Neutral Q14CA7 F200S Neutral Neutral P08514 E355K Disease Disease P08514 F222L Disease Disease P08514 G267E Disease Disease P08514 I874S Neutral Neutral P08514 P176A Disease Disease P08514 R755P Disease Disease P53708 Q581P Neutral Disease P08514 L214P Disease Disease P08514 T40I Neutral Neutral P08514 F202C Disease Disease P08514 G273D Disease Disease P53708 V216L Neutral Neutral P08514 Y968N Neutral Disease P08514 V982M Disease Neutral P08514 G412R Disease Disease P08514 V329F Disease Disease P53708 R748H Neutral Neutral P08514 I405T Disease Disease P08514 R358H Disease Disease P08514 C161W Disease Disease P08514 I596T Disease Disease P08514 F320S Disease Disease P08514 G449D Disease Disease P08514 L847P Disease Disease P08514 Q778P Disease Disease P08514 A139V Disease Disease P08514 Y174H Disease Neutral P08514 T207I Disease Neutral P53708 I993V Neutral Neutral P08514 P943L Disease Neutral P08514 R1026Q Disease Disease P08514 A581D Disease Disease P08514 P176L Disease Disease P53708 A994V Neutral Neutral P53708 V567L Neutral Neutral P08514 C705R Disease Disease P53708 S577F Neutral Neutral P06756 I405V Neutral Neutral P08514 L86P Disease Disease P08514 G380D Disease Disease P06756 V783I Neutral Neutral P08514 L752V Disease Neutral P08514 A989T Neutral Neutral Q9BQG2 I235V Neutral Neutral Q9BQG2 K129E Neutral Neutral Q6XQN6 A57V Neutral Neutral Q96N77 S231C Neutral Neutral Q96N77 Q363P Neutral Neutral O15069 D438E Neutral Neutral O15069 V498A Neutral Neutral O15069 D1105E Neutral Neutral O15069 K591E Neutral Neutral O15069 C1152F Neutral Neutral Q5T7V8 E320K Neutral Neutral Q8IYD1 P23T Neutral Neutral Q9BTC0 P13L Neutral Neutral Q9BTC0 P276L Neutral Disease Q9HA72 V194M Neutral Neutral Q7Z7F7 R24C Neutral Neutral Q8N6M0 R283Q Neutral Neutral P31942 N163S Neutral Neutral Q8N6M6 V179A Neutral Neutral P28335 C23S Neutral Neutral Q9UHD8 R106W Disease Neutral Q9UHD8 P145L Neutral Neutral Q9UHD8 S111F Disease Neutral Q9UHD8 R76C Neutral Neutral Q9UHD8 M576V Neutral Neutral Q99689 D123E Neutral Neutral Q96BR5 R219K Neutral Neutral O14745 L110V Neutral Neutral Q7LDG7 G493A Neutral Neutral O00522 K569E Disease Neutral O00522 F97S Disease Neutral Q8N309 Q256K Neutral Disease Q92973 D26E Neutral Neutral Q14241 V298I Neutral Neutral Q14241 T119M Neutral Neutral Q14241 A490V Neutral Neutral Q9GZR3 R189C Neutral Neutral Q9GZR3 R112C Disease Disease Q9GZR3 R78W Neutral Neutral Q96AQ9 P123R Neutral Neutral Q96AQ9 K48E Neutral Neutral Q96AQ9 R107Q Neutral Neutral Q96AQ9 S215I Neutral Neutral Q96AQ9 E226D Neutral Neutral Q92561 R21S Neutral Neutral Q9H251 R2833G Disease Disease Q9H251 R2956C Disease Neutral Q9H251 D124G Disease Disease Q9H251 V2283I Neutral Neutral Q9H251 A1586P Disease Neutral Q9H251 T1209A Disease Neutral Q9H251 L480Q Disease Neutral Q9H251 N452S Disease Neutral Q9H251 T1887I Neutral Neutral Q9H251 R2066Q Neutral Neutral Q9H251 D2148N Disease Neutral Q9H251 E2588Q Neutral Neutral Q9H251 S2517G Disease Neutral Q9H251 A484P Disease Neutral Q9H251 N2962S Neutral Neutral Q9H251 R2358Q Neutral Neutral Q9H251 R1507Q Disease Neutral Q9H251 E1595K Disease Neutral Q9H251 D2202N Disease Neutral Q9H251 G2744S Disease Disease Q9H251 T1999S Neutral Neutral Q9H251 R2465W Disease Neutral Q9H251 I2950N Disease Disease Q9H251 R2608H Disease Disease Q9H251 R3175H Disease Neutral Q9H251 T1575A Neutral Neutral Q9H251 P3059T Disease Neutral Q9H251 Q1496H Disease Neutral Q9H251 R582Q Disease Neutral Q9H251 R1804Q Neutral Neutral Q9H251 S496N Neutral Neutral Q9H251 R1060W Disease Disease Q9H251 E247K Disease Disease Q9H251 P2380L Neutral Neutral Q9H251 D990N Disease Neutral Q9H251 T1671S Neutral Neutral Q9H251 V2933E Neutral Disease Q9H251 V1620M Neutral Neutral Q9H251 D2045N Disease Neutral Q9H251 G2017S Disease Disease Q9H251 R3C Neutral Neutral Q9H251 R1746Q Disease Neutral Q9H251 R1349C Neutral Neutral Q9H251 S3245F Disease Neutral Q9H251 R1437Q Neutral Neutral Q9H251 G490A Neutral Disease Q9H251 D2954N Neutral Neutral Q9H251 P1206R Disease Neutral Q9H251 A1222T Neutral Neutral Q9H251 E2044K Neutral Neutral Q9H251 F3125L Neutral Neutral Q9H251 A366T Disease Neutral Q9H251 D1846N Disease Neutral Q9H251 D1351N Neutral Neutral Q9H251 V1675I Neutral Neutral Q9H251 G1186D Disease Disease Q9H251 R3189W Disease Neutral Q9H251 F1888S Disease Neutral Q9H251 D1341N Disease Neutral Q9H251 D2376N Neutral Neutral Q8TED4 G268S Neutral Neutral Q9NZI7 T212A Neutral Disease O14763 P32L Neutral Neutral O14763 A67V Neutral Neutral Q8N8U9 R555W Neutral Disease Q9UMX1 P15L Neutral Neutral Q9UMX1 A340S Neutral Neutral Q5W186 L48F Neutral Neutral Q9P1Z0 M550I Neutral Neutral P11168 L478V Neutral Neutral P11168 V101I Neutral Neutral P11168 T110I Neutral Disease P11168 P417L Disease Disease P11168 L389P Disease Disease P11168 P68L Neutral Disease P11168 V423E Disease Disease P11161 D355V Disease Neutral P11161 R409W Disease Neutral P11161 D383Y Disease Neutral P11161 R381H Disease Neutral P11161 R381C Disease Neutral P11161 I268N Disease Disease P11161 R359W Disease Neutral Q6ZS11 P288L Neutral Neutral Q8N9T8 E185A Neutral Neutral Q8N9T8 T5A Neutral Neutral Q8N9T8 L451P Neutral Neutral Q8N9T8 R342W Neutral Neutral Q8N9T8 S709P Neutral Neutral Q8N9T8 E272K Neutral Neutral Q8N9T8 E355Q Neutral Neutral Q8N9T8 G144R Neutral Neutral Q8N9T8 S315L Neutral Neutral P50443 G255E Disease Disease P50443 A715V Disease Disease P50443 C653S Disease Disease P50443 G678V Disease Disease P50443 R279W Disease Disease P50443 T689S Neutral Neutral P50443 N425D Disease Disease Q6XXX2 N39K Neutral Neutral Q6XXX2 S21T Neutral Neutral Q6XXX2 M104R Neutral Disease Q6XXX2 A52S Neutral Neutral P21462 N192K Neutral Disease P30556 T336P Neutral Disease P25106 L219W Neutral Disease P30556 L48V Neutral Disease P30556 A163T Neutral Neutral P21462 A346E Neutral Neutral P30556 C289W Neutral Neutral P21462 L101V Neutral Neutral P30556 T282M Disease Neutral P30556 A244S Neutral Neutral Q9H0P0 G280R Disease Disease Q9H0P0 L181P Disease Disease Q9H0P0 D137V Disease Disease Q9H0P0 N229S Disease Disease Q9UQ84 R503T Neutral Neutral Q9UQ84 G759E Neutral Neutral Q9UQ84 R634Q Neutral Neutral Q9UQ84 S610G Neutral Neutral Q9UQ84 E670G Neutral Neutral Q9UQ84 S456Y Neutral Neutral Q9UQ84 A137S Neutral Neutral Q9UQ84 H354R Neutral Neutral Q9UQ84 N279S Neutral Neutral Q9UQ84 T439M Neutral Neutral Q9UQ84 E589K Neutral Neutral Q9UQ84 P640A Neutral Neutral Q9UQ84 V27A Neutral Disease Q9UQ84 P757L Neutral Neutral Q9UQ84 N299S Neutral Neutral Q9UQ84 R93G Neutral Disease Q9UQ84 F438C Neutral Neutral Q9UQ84 V460L Neutral Neutral Q9UQ84 A827V Neutral Neutral Q9UQ84 H726P Neutral Neutral Q9UQ84 R723C Neutral Neutral Q9UQ84 D428N Neutral Neutral Q9UQ84 V458M Neutral Neutral Q9UQ84 V76I Neutral Neutral Q8TB68 P127H Neutral Neutral Q8N3I7 R207H Disease Neutral Q8N3I7 N184S Disease Disease Q9NZE8 A80P Neutral Disease Q9NZE8 P19S Neutral Neutral O43147 L63M Neutral Neutral O43147 R374Q Neutral Neutral O43147 R238K Neutral Neutral O43147 H329R Neutral Disease O43147 D968V Neutral Disease O43147 R244S Neutral Disease Q92667 V60M Neutral Neutral P20062 I219L Neutral Neutral P20062 M198T Neutral Disease P20062 P259R Neutral Neutral P20062 S376L Neutral Neutral Q9BSL1 E374D Neutral Neutral Q9P2K9 L51V Neutral Neutral Q9P2K9 G182S Neutral Neutral Q9P2K9 A650T Neutral Neutral Q9P2K9 R948H Neutral Neutral Q9P2K9 G661A Neutral Neutral P17405 G577S Disease Neutral P17405 Y537H Disease Disease P17405 V36A Neutral Neutral P17405 E246Q Disease Neutral P17405 N383S Disease Disease P17405 G242R Disease Disease P17405 P475L Disease Disease P17405 L302P Disease Disease P17405 S248R Disease Neutral P17405 H319Y Disease Disease P17405 N389T Disease Disease P17405 P371S Disease Neutral P17405 M382I Disease Disease P17405 R496L Disease Disease P17405 H421Y Disease Neutral P17405 Y446C Disease Disease P17405 W391G Disease Disease P17405 F463S Disease Disease P17405 S436R Disease Disease P54277 E27Q Neutral Disease P54277 G501R Neutral Disease P54277 R202K Neutral Neutral P54277 M394T Neutral Neutral P54277 Y793H Neutral Neutral P54277 N632S Neutral Neutral P54277 E720D Neutral Neutral P02671 E545V Disease Neutral P02671 R573L Disease Neutral P02671 K446E Neutral Neutral P02671 I6V Neutral Neutral P02671 T456A Neutral Neutral P02671 S66T Neutral Neutral P02671 T331A Neutral Neutral Q70Z44 R225H Neutral Disease Q70Z44 R435H Neutral Disease Q70Z44 A171G Neutral Neutral Q9NZC2 D134G Disease Disease Q9NZC2 H157Y Neutral Neutral Q9NZC2 K186N Disease Disease Q9NZC2 L211P Neutral Neutral Q9NZC7 L291P Disease Disease Q9NZC7 P282A Neutral Neutral Q9NZC7 T111S Disease Neutral Q9NZC7 L272F Neutral Neutral Q9NZC7 A179T Neutral Neutral Q9NZC7 R314H Disease Neutral Q9NZC7 R120W Disease Neutral Q9NZC7 P98L Neutral Disease P08588 R389L Neutral Disease P08588 S49G Neutral Neutral P08588 R389G Neutral Disease P02787 R42L Neutral Disease P02787 K646E Neutral Neutral P02787 G142S Neutral Disease P02787 S55R Neutral Neutral P02787 A76V Neutral Disease P02787 T645P Neutral Disease P02787 A477P Disease Disease P02788 E579D Neutral Neutral P02787 G671E Neutral Disease P02787 P589S Neutral Neutral P02788 G422C Neutral Disease P02788 A29T Neutral Neutral P02787 W377C Neutral Disease P02787 D77N Disease Disease P02788 K47R Neutral Neutral P02787 G562V Neutral Disease P08582 R294W Neutral Neutral P02787 D296G Neutral Neutral P02787 G277S Neutral Neutral P02787 H319R Neutral Neutral P02788 I148T Neutral Disease Q4G0X9 A8P Neutral Neutral Q8N1A6 R40M Neutral Neutral Q8N1A6 S104L Neutral Neutral Q8N1A6 V107M Neutral Neutral Q8N1A6 H166R Neutral Disease Q6UXU6 S90N Neutral Neutral Q6UXU6 S90T Neutral Neutral A4D161 C95R Neutral Neutral A4D161 Y20H Neutral Disease A4D161 S240G Neutral Neutral A4D161 A90T Neutral Neutral A4D161 H128R Neutral Disease Q9Y6Q6 A192V Neutral Neutral P28288 G17D Disease Disease Q5SQN1 R3G Neutral Neutral Q5SQN1 V109M Neutral Neutral Q5SQN1 G74R Neutral Disease Q5SQN1 R336C Neutral Neutral Q14393 F41L Neutral Neutral Q14393 R659Q Neutral Neutral Q14393 E655K Neutral Neutral Q14393 G543R Neutral Neutral Q14393 S623L Neutral Neutral Q14393 V390M Neutral Neutral Q14393 S231Y Neutral Neutral Q9GZX5 S472P Neutral Disease Q9GZX5 V524I Neutral Neutral Q9GZX5 P66L Neutral Disease Q9GZX5 S501R Neutral Neutral Q16667 D94V Disease Disease Q16667 N187S Disease Neutral Q16667 W31R Disease Disease Q16667 F78L Disease Neutral Q16667 N91K Disease Neutral Q16667 K195I Disease Disease Q16667 C79Y Disease Disease Q16667 I108V Disease Neutral Q16667 L95F Disease Neutral Q5TD94 L589P Neutral Neutral Q5TD94 T149S Neutral Neutral Q5TD94 A700V Neutral Neutral Q5TD94 R556H Neutral Disease Q5TD94 N627H Neutral Disease O00408 T224I Neutral Neutral P17787 V287L Disease Neutral Q04844 S163L Disease Disease Q04844 L98P Disease Disease Q07001 P271Q Disease Disease P02708 N262K Disease Disease Q07001 Q288E Disease Disease Q07001 E80K Disease Neutral Q04844 P265L Disease Disease P02708 C463W Disease Disease P02708 D383V Neutral Neutral P02708 V330I Disease Neutral P02708 G198S Disease Disease Q04844 G13R Disease Disease P02708 V294F Disease Disease P02708 V177L Disease Disease Q04844 R331W Disease Disease Q04844 T284P Disease Disease P30926 R136W Neutral Disease P17787 V287M Disease Neutral P07510 A149T Neutral Neutral Q04844 P141L Disease Disease P07510 V107G Disease Disease Q04844 R167L Disease Disease P07510 R239C Disease Disease P02708 F301L Disease Neutral Q04844 A431P Disease Disease P02708 V201M Disease Disease P02708 F278V Disease Disease P02708 T299I Disease Disease Q04844 L241F Disease Disease P30926 S140G Neutral Neutral P11230 L285M Disease Neutral P30926 M467V Neutral Disease Q07001 S289F Disease Disease Q04844 L289F Disease Disease P02708 S314I Disease Neutral P11230 V289M Disease Neutral P17787 Q397H Neutral Neutral Q9NYG8 P328L Neutral Neutral O75364 S13N Disease Neutral P20851 P198S Neutral Neutral P20851 K102Q Neutral Neutral Q9BSJ5 F356L Neutral Disease Q9BSJ5 C396R Neutral Neutral Q9BSJ5 K322Q Neutral Neutral Q9BSJ5 A522T Neutral Neutral Q9BSJ5 G226S Neutral Neutral Q9BSJ5 N395H Neutral Neutral Q9BSJ5 Q420H Neutral Neutral Q9NRG4 G165E Neutral Neutral Q9NRG9 S263P Disease Disease Q9NRG9 H160R Disease Neutral Q9NRG9 K108M Neutral Neutral Q9NRG9 Q15K Disease Neutral Q9UPQ3 D148G Neutral Disease Q9UPQ3 V671I Neutral Neutral Q9UPQ3 E829K Neutral Disease O00462 T701M Neutral Neutral O00462 V253I Neutral Neutral P00451 G266E Disease Disease P00451 H275L Disease Disease P00451 R550H Disease Neutral P00451 A111T Disease Disease P00451 P1873R Disease Disease P00451 E739K Disease Neutral P00451 V682F Disease Neutral P00451 R1800C Disease Disease P00451 M110V Disease Neutral P00451 V2035A Disease Disease P00451 L327P Disease Disease P00451 Q1705H Disease Neutral P00451 S1803Y Disease Disease P00451 M633I Disease Disease P00451 R560T Disease Neutral P00451 R2169H Disease Disease P00451 K67E Disease Disease P00451 A2058P Disease Disease P00451 Q2119R Disease Neutral P00451 S179P Disease Disease P00451 A1939T Disease Neutral P00451 R2182P Disease Disease P00451 C348R Disease Disease P00451 R795G Neutral Neutral P00451 R2326P Disease Disease P00451 G1769R Disease Neutral P00451 K185T Disease Disease P00451 N631S Disease Disease P00451 E1057K Disease Neutral P00451 N254I Disease Disease P00451 R301H Disease Disease P00451 R550G Disease Neutral P00451 E1723K Disease Disease P00451 L2229F Disease Disease P00451 H1066Y Disease Neutral P00451 M721I Disease Disease P00451 T479R Disease Disease P00451 S603I Disease Disease P00451 L1481P Neutral Neutral P00451 M1842I Disease Neutral P00451 R2178L Disease Disease P00451 P2067L Disease Disease P00451 T294I Disease Disease P00451 I567T Disease Disease P00451 I1782R Disease Disease P00451 C348S Disease Disease P00451 A2211P Disease Disease P00451 W412R Disease Disease P00451 D544N Disease Disease P00451 R2323C Disease Disease P00451 T2173I Disease Neutral P00451 L431S Disease Disease P00451 E1904D Disease Disease P00451 A1939V Disease Disease P00451 V727F Disease Disease P00451 P470L Disease Disease P00451 L327V Disease Neutral P00451 T137I Disease Disease P00451 T541S Disease Neutral P00451 Y492C Disease Disease P00451 K1751Q Disease Disease P00451 L594Q Disease Disease P00451 R717L Disease Disease P00451 G474R Disease Disease P00451 D75E Disease Disease P00451 E141K Disease Neutral P00451 R301C Disease Disease P00451 V104D Disease Disease P00451 N1941S Disease Disease P00451 Y2124C Disease Disease P00451 Y2036C Disease Neutral P00451 F214V Disease Disease P00451 E1848G Disease Disease P00451 V1012L Disease Neutral P00451 I331V Disease Neutral P00451 A663V Disease Neutral P00451 M1945V Disease Disease P00451 N299I Disease Disease P00451 G720S Disease Disease P00451 K1864E Disease Disease P00451 S635N Disease Disease P00451 M586V Disease Neutral P00451 R2178C Disease Disease P00451 R602G Disease Neutral P00451 T454I Disease Disease P00451 S577F Disease Disease P00451 N583S Disease Neutral P00451 L1875P Disease Disease P00451 D101V Disease Disease P00451 R2228G Disease Disease P00451 W274C Disease Disease P00451 L117F Disease Disease P00451 Y683N Disease Disease P00451 Y133C Disease Disease P00451 G513S Disease Neutral P00451 S1965I Disease Disease P00451 P2319S Disease Disease P00451 L1882P Disease Disease P00451 R2323H Disease Disease P00451 G41C Disease Neutral P00451 H1973L Disease Disease P00451 S308L Disease Disease P00451 L1951F Disease Neutral P00451 I307S Disease Disease P00451 G2344C Disease Disease P00451 S176P Disease Disease P00451 L326P Disease Disease P00451 G2198V Disease Disease P00451 F2279I Disease Disease P00451 F2120C Disease Disease P00451 M699T Disease Disease P00451 L117R Disease Disease P00451 P2319L Disease Disease P00451 V99D Disease Disease P00451 G164D Disease Disease P00451 K444R Disease Disease P00451 V159A Disease Neutral P00451 L69P Disease Disease P00451 P470R Disease Disease P00451 M1791T Disease Neutral P00451 E129V Disease Disease P00451 I494T Disease Disease P00451 A303E Disease Disease P00451 N1460K Disease Disease P00451 Y639C Disease Disease P00451 Y24C Disease Disease P00451 D222V Disease Disease P00451 A111V Disease Disease P00451 D588G Disease Disease P00451 S554C Disease Disease P00451 C2040Y Disease Disease P00451 G498R Disease Disease P00451 V220G Disease Disease P00451 W2015C Disease Disease P00451 G1779R Disease Disease P00451 E409G Disease Disease P00451 E291G Disease Disease P00451 R490G Disease Disease P00451 E223K Disease Disease P00451 L650F Disease Neutral P00451 T2105N Disease Disease P00451 S2082N Disease Disease P00451 S554G Disease Disease P00451 R2326G Disease Disease P00451 R2016W Disease Disease P00451 N637S Disease Disease P00451 T2004R Disease Disease P00451 G1967D Disease Disease P00451 A303P Disease Disease P00451 A1610S Disease Neutral P00451 R2016P Disease Disease P00451 G477V Disease Disease P00451 L1808F Disease Disease P00451 W33G Disease Disease P00451 G1979V Disease Disease P00451 F1982I Disease Disease P00451 G439D Disease Disease P00451 N1941D Disease Disease P00451 N601K Disease Disease P00451 N1971T Disease Neutral P00451 R2323L Disease Disease P00451 Y605S Disease Disease P00451 I2051S Disease Disease P00451 R48K Disease Neutral P00451 H1980Y Disease Disease P00451 L1777P Disease Disease P00451 A219D Disease Disease P00451 G224W Disease Disease P00451 L1994P Disease Disease P00451 N2038S Disease Neutral P00451 G705V Disease Disease P00451 E2200D Disease Disease P00451 A1798P Disease Disease P00451 F484C Disease Disease P00451 R2182H Disease Disease P00451 G2107S Disease Disease P00451 R717W Disease Disease P00451 G2022D Disease Disease P00451 W401G Disease Disease P00451 Y1909C Disease Disease P00451 G2000A Disease Neutral P00451 D135Y Disease Disease P00451 R2228Q Disease Disease P00451 N637D Disease Disease P00451 V2251E Disease Disease P00451 E30V Disease Disease P00451 T2141N Disease Neutral P00451 M701I Disease Disease P00451 T137A Disease Neutral P00451 F677L Disease Disease P00451 P1801A Disease Disease P00451 D2093Y Disease Disease P00451 W1908L Disease Disease P00451 G2028R Disease Disease P00451 W2248S Disease Disease P00451 L431F Disease Neutral P00451 H1980P Disease Disease P00451 L2185W Disease Neutral P00451 G89V Disease Disease P00451 G92A Disease Disease P00451 K67N Disease Disease P00451 L644V Disease Neutral P00451 I405F Disease Disease P00451 A723T Disease Neutral P00451 M1966I Disease Disease P00451 R1985Q Disease Neutral P00451 Q584H Disease Disease P00451 G710W Disease Disease P00451 I438F Disease Disease P00451 W604C Disease Disease P00451 R1715G Disease Disease P00451 N609I Disease Disease P00451 R1800G Disease Disease P00451 S1858C Disease Disease P00451 G1779E Disease Disease P00451 L217H Disease Disease P00451 R301L Disease Disease P00451 I2117F Disease Disease P00451 S138R Disease Neutral P00451 A488G Disease Disease P00451 A315V Disease Neutral P00451 E98K Disease Disease P00451 S2192I Disease Neutral P00451 M2183R Disease Disease P00451 A2220P Disease Disease P00451 G2344S Disease Disease P00451 E475K Disease Disease P00451 R1960Q Disease Neutral P00451 A1853V Disease Neutral P00451 V1876L Disease Disease P00451 R437W Disease Disease P00451 A97P Disease Disease P00451 S19R Disease Disease P00451 M2257V Disease Neutral P00451 E2018G Disease Neutral P00451 L1771P Disease Neutral P00451 L659P Disease Disease P00451 Q1336K Disease Neutral P00451 R1740G Disease Neutral P00451 D75V Neutral Disease P00451 Y1998C Disease Disease P00451 S1907R Disease Disease P00451 P2196R Disease Neutral P00451 D1260E Neutral Neutral P00451 L1963P Disease Disease P00451 G439V Disease Disease P00451 L26P Disease Disease P00451 R550C Disease Disease P00451 R391H Disease Disease P00451 R2326Q Disease Disease P00451 E132D Disease Neutral P00451 I2281T Disease Neutral P00451 R1960L Disease Disease P00451 V297A Disease Neutral P00451 D2307A Disease Disease P00451 I585R Disease Neutral P00451 V285G Disease Disease P00451 M699V Disease Disease P00451 R1768H Disease Disease P00451 D145H Disease Disease P00451 G1942A Disease Disease P00451 S603R Disease Disease P00451 W2332R Disease Disease P00451 V181M Disease Neutral P00451 M2007I Disease Disease P00451 P165S Disease Disease P00451 F698L Disease Neutral P00451 D75Y Disease Disease P00451 G164V Disease Disease P00451 R2135P Disease Disease P00451 K108T Disease Disease P00451 E291K Disease Disease P00451 C2193G Disease Disease P00451 T2264A Disease Disease P00451 R2323G Disease Disease P00451 P540T Disease Disease P00451 H113Y Disease Neutral P00451 Q2106E Disease Disease P00451 V253F Disease Disease P00451 R1800H Disease Disease P00451 P2224L Disease Disease P00451 I2056N Disease Disease P00451 S596P Disease Disease P00451 W2065R Disease Disease P00451 Y1728C Disease Disease P00451 M1966V Disease Disease P00451 E1701K Disease Neutral P00451 I2117S Disease Disease P00451 G278R Disease Disease P00451 D186G Disease Disease P00451 L1775V Disease Disease P00451 R22T Disease Disease P00451 Y1802C Disease Disease P00451 I1698T Disease Neutral P00451 D2093G Disease Disease P00451 R2169C Disease Disease P00451 R2228P Disease Disease P00451 Q2106R Disease Disease P00451 G1869V Disease Disease P00451 S553P Disease Disease P00451 L2185S Disease Disease P00451 F2145C Disease Disease P00451 Y35H Disease Disease P00451 R1888I Disease Neutral P00451 F295L Disease Disease P00451 Y605H Disease Disease P00451 D478N Disease Disease P00451 W532G Disease Disease P00451 D135G Disease Disease P00451 Y1699C Disease Neutral P00451 D1727V Disease Disease P00451 N2157D Disease Disease P00451 F2279C Disease Neutral P00451 R48C Disease Neutral P00451 I2204T Disease Disease P00451 D101G Disease Disease P00451 K427I Disease Disease P00451 F2120L Disease Neutral P00451 R1708C Disease Disease P00451 G255V Disease Disease P00451 D186Y Disease Disease P00451 G2045E Disease Disease P00451 Y450D Disease Disease P00451 G193R Disease Disease P00451 K529E Disease Neutral P00451 C2345S Disease Disease P00451 Y442C Disease Disease P00451 C172W Disease Disease P00451 C348Y Disease Disease P00451 Y155H Disease Disease P00451 Y35C Disease Disease P00451 C1877R Disease Disease P00451 Y365C Disease Neutral P00451 M721L Disease Disease P00451 H2174D Disease Disease P00451 S1799H Disease Disease P00451 M2183V Disease Neutral P00451 A219T Disease Neutral P00451 S2088F Disease Disease P00451 P470T Disease Disease P00451 D1788H Disease Disease P00451 D588Y Disease Disease P00451 D1865N Disease Disease P00451 P1844S Disease Disease P00451 S392L Disease Disease P00451 R546W Disease Neutral P00451 T314I Disease Disease P00451 G263S Disease Disease P00451 N631K Disease Disease P00451 G439S Disease Disease P00451 Q664P Disease Disease P00451 Q2330P Disease Neutral P00451 H113R Disease Neutral P00451 D561Y Disease Disease P00451 A2070V Disease Disease P00451 G2304V Disease Disease P00451 G720D Disease Disease P00451 S2138Y Disease Disease P00451 R437P Disease Disease P00451 L26R Disease Disease P00451 N713I Disease Disease P00451 L725Q Disease Disease P00451 L1775F Disease Neutral P00451 R2178H Disease Neutral P00451 E1904K Disease Disease P00451 R2339T Disease Disease P00451 C2345Y Disease Disease P00451 D561H Disease Disease P00451 G466E Disease Disease P00451 H1867P Disease Disease P00451 E72K Disease Disease P00451 S392P Disease Disease P00451 V653M Disease Neutral P00451 R2228L Disease Disease P00451 D1865Y Disease Disease P00451 W2290L Disease Disease P00451 E340K Disease Neutral P00451 I1901F Disease Disease P00451 Y742C Disease Neutral P00451 H1867R Disease Neutral P00451 G130R Disease Disease P00451 F455C Disease Disease P00451 G121S Disease Disease P00451 D101H Disease Disease P00451 T1845P Disease Disease P00451 Y683C Disease Disease P00451 I405S Disease Disease P00451 A1853T Disease Neutral P00451 W2248C Disease Disease P00451 T1714S Disease Neutral P00451 P2172R Disease Disease P00451 S2030N Disease Neutral P00451 R2109C Disease Disease P00451 G89D Disease Disease P00451 Y1699F Disease Neutral P00451 V181E Disease Disease P00451 P1780L Disease Disease P00451 M339T Disease Disease P00451 C267Y Disease Disease P00451 G323E Disease Disease P00451 R1708H Disease Disease P00451 R612C Disease Disease P00451 V147D Disease Disease P00451 S202N Disease Neutral P00451 R391P Disease Disease P00451 P262L Disease Disease P00451 E284K Disease Disease P00451 Q584R Disease Neutral P00451 T314A Disease Disease P00451 R2326L Disease Disease P00451 V345L Disease Disease P00451 G474E Disease Disease P00451 R503H Disease Neutral P00451 D579A Disease Neutral P00451 S1968R Disease Disease P00451 S189L Disease Disease P00451 V653A Disease Neutral P00451 P2162L Disease Disease P00451 T252I Disease Disease P00451 D561G Disease Disease P00451 S202R Disease Neutral P00451 I585T Disease Neutral P00451 I2209N Disease Disease P00451 G2045V Disease Disease P00451 G1872E Disease Disease P00451 Y25C Disease Disease P00451 F1804S Disease Disease P00451 N163K Disease Neutral P00451 R391C Disease Disease P00451 Y450N Disease Disease P00451 G1869D Disease Disease P00451 M681I Disease Neutral P00451 Q584K Disease Disease P00451 E1894G Disease Disease P00451 V2251A Disease Disease P00451 V556D Disease Disease P00451 W412G Disease Disease P00451 C198G Disease Disease P00451 V578A Disease Neutral P00451 V2242M Neutral Neutral P00451 S1907C Disease Disease P00451 T686R Disease Disease P00451 I522Y Disease Disease P00451 G92V Disease Disease P00451 Q2265R Disease Disease P00451 P947R Disease Neutral P00451 R2182C Disease Disease P00451 Y492H Disease Disease P00451 V345A Disease Disease P00451 F312S Disease Neutral P00451 P2172Q Disease Disease P00451 D579H Disease Neutral P00451 C329F Disease Disease P00451 T2173A Disease Neutral P00451 N2148S Disease Disease P00451 N601D Disease Disease P42166 Q599E Neutral Neutral Q9BSQ5 V120I Neutral Neutral Q9BSQ5 L198R Disease Disease Q9BSQ5 V53I Neutral Neutral Q8IWK6 V1043M Neutral Neutral Q8IWK6 V1166G Neutral Neutral Q9HCF6 Q1695R Neutral Neutral Q86V40 H143R Neutral Neutral Q86V40 R379Q Neutral Neutral Q86V40 P381L Neutral Neutral Q86V42 D181H Neutral Neutral Q5JVL4 R182H Disease Neutral Q5JVL4 R221H Disease Neutral Q5JVL4 D210N Disease Neutral Q5JVL4 F229L Disease Neutral Q5JVL4 P77T Disease Neutral Q5JVL4 R285I Neutral Disease Q5JVL4 D253Y Disease Disease Q86UT8 W244G Neutral Disease Q8IVT2 K232R Neutral Neutral Q8IVT2 E653G Neutral Neutral Q8IVT2 S156G Neutral Neutral A0PJW8 A66T Neutral Neutral A0PJW8 L60P Neutral Disease O75752 D126N Neutral Neutral Q8N543 P173S Neutral Disease O43736 A72V Neutral Neutral Q9NQX7 G53S Neutral Neutral O43736 R230T Neutral Neutral Q07092 T62K Neutral Neutral O95163 R696P Disease Disease P02655 W48R Disease Disease P02655 K77Q Neutral Neutral P02655 E60K Neutral Neutral P02655 K41T Neutral Neutral P15884 R576W Disease Disease P15884 R576Q Disease Disease P01303 L22M Neutral Neutral P01303 L7P Neutral Neutral Q8N485 R3I Neutral Neutral P56856 M149L Neutral Neutral Q03701 K303R Neutral Neutral Q03701 I102V Neutral Neutral Q03701 P15S Neutral Neutral Q5SVQ8 D327Y Neutral Neutral Q2M1Z3 T1380I Neutral Neutral Q2M1Z3 V1366M Neutral Neutral Q2M1Z3 S803G Neutral Neutral Q2M1Z3 I1115L Neutral Neutral Q2M1Z3 P221L Neutral Neutral P11678 R286H Disease Disease P11678 R326P Neutral Disease P22079 T105I Neutral Neutral P11678 H496Q Neutral Neutral P11678 P292L Neutral Neutral P22079 I614T Neutral Neutral P11678 I40M Neutral Neutral P05164 R569W Disease Disease P11678 N572Y Neutral Disease P22079 V421M Neutral Neutral P11678 A249E Neutral Neutral P11678 K441T Neutral Neutral P11678 P358L Neutral Neutral P22079 A244T Neutral Neutral P22079 R414Q Neutral Disease P11678 K276R Neutral Neutral P22079 D700N Neutral Disease P11678 R364H Neutral Neutral P22079 R514Q Neutral Neutral P11678 Q122H Neutral Neutral P05164 Y173C Disease Disease P05164 M251T Disease Disease Q1MSJ5 R872H Neutral Neutral P21583 T54A Neutral Neutral P21583 F232Y Neutral Neutral Q8N3E9 P652L Neutral Disease P98082 T586I Neutral Neutral Q9ULT0 V538L Neutral Neutral Q92752 G293S Neutral Neutral Q92752 V17I Neutral Neutral Q92752 A128S Neutral Neutral Q92752 R643K Neutral Neutral Q9NVE5 R1111C Neutral Neutral Q9NVE5 V666A Neutral Neutral Q9C0C2 S322T Neutral Neutral Q9C0C2 S714N Neutral Neutral Q9H665 W189R Neutral Neutral Q04756 F231L Neutral Neutral Q04756 V225M Neutral Neutral Q04756 R509H Neutral Neutral Q04756 R644Q Neutral Disease O75792 G37S Disease Disease O75792 L202S Neutral Neutral O75792 A258G Neutral Neutral O60312 A784T Neutral Neutral O60312 W1172C Neutral Disease O60312 R1298S Neutral Neutral O60312 I1188V Neutral Neutral O60312 A1179T Neutral Disease O60312 T532M Neutral Neutral Q8IUD6 R286H Disease Neutral Q8IUD6 H71Q Neutral Neutral Q8IUD6 S108P Neutral Neutral P31276 S50I Neutral Neutral P31271 N372H Disease Disease P31271 Q371L Disease Disease O60673 V3064I Neutral Neutral O60673 Q231H Neutral Neutral O60673 I2075M Neutral Neutral O60673 R962Q Neutral Neutral O60673 G1923R Neutral Neutral O60673 K1540E Neutral Neutral O60673 R1970H Neutral Neutral O60673 S1724T Neutral Neutral O60673 D1812H Neutral Neutral O60673 R2762Q Neutral Neutral O60673 S1576L Neutral Neutral O60673 Q1469P Neutral Neutral O60673 E2015V Neutral Neutral O60673 D1713N Neutral Neutral O60673 Q397P Neutral Neutral O60673 M693T Neutral Neutral O60673 P1339T Neutral Neutral O60673 S389T Neutral Neutral O60673 Q1309H Neutral Neutral O60673 S2607T Neutral Neutral O60673 T1224I Neutral Neutral O60673 P1791S Neutral Neutral O60673 Y1156C Neutral Neutral O60673 S1302T Neutral Neutral Q6GMV1 D135N Neutral Neutral Q6GMV1 G184S Neutral Neutral Q6GMV1 I159T Neutral Neutral Q5JQC9 A673G Neutral Neutral Q5TH69 S689A Neutral Neutral Q5TH69 A1571T Neutral Neutral Q5TH69 K2031R Neutral Neutral P52952 C114S Disease Disease P52952 R25C Disease Neutral P52952 K192R Disease Disease P52952 L7P Disease Neutral P52952 P275T Disease Neutral P52952 Q187H Disease Disease P52952 K118R Disease Neutral P52952 A127E Disease Neutral P52952 P77L Disease Neutral P52952 R322Q Disease Neutral P52952 R190C Disease Disease P52952 A286V Disease Neutral P52952 S45P Disease Neutral P52952 Q22P Disease Disease P52952 K183E Disease Disease P52952 N188K Disease Disease P52952 A135T Disease Neutral P52952 Y191C Disease Disease P52952 V205E Disease Neutral P52952 S305G Disease Neutral P52952 N294H Disease Neutral P52952 Y248H Disease Disease P52952 A219V Disease Disease P52952 A63V Disease Neutral P52952 R216C Disease Disease P52952 S279F Disease Neutral P52952 E21Q Disease Disease P52952 C114R Disease Disease P52952 F51L Disease Neutral P52952 A281V Disease Neutral P52952 K192T Disease Disease P52952 E126V Disease Neutral P52952 K194R Disease Disease P52952 K15I Disease Disease P52952 T178M Disease Disease P52952 R189G Disease Disease P52952 R142C Disease Disease P52952 L144P Disease Disease P52952 G320S Disease Disease P52952 A323T Disease Neutral P52952 L69P Disease Neutral P52952 D226N Disease Disease P52952 S279P Disease Neutral P52952 D299G Disease Neutral P52952 K124R Disease Neutral P52952 N19S Disease Neutral P52952 P133S Disease Neutral P16615 G310V Disease Disease P16615 I348T Disease Disease P16615 D702N Disease Disease O14983 P789L Disease Disease P16615 C560R Disease Disease P16615 S920Y Disease Disease P16615 H943R Disease Disease P98194 L584P Disease Disease P16615 P975R Disease Neutral P16615 T357K Disease Disease P16615 K683E Disease Disease P16615 V223M Disease Disease P16615 P160L Disease Disease P16615 R131Q Disease Disease P16615 S186P Disease Neutral P98194 T709M Disease Neutral P16615 N39T Disease Disease P16615 A745D Disease Disease P98194 A304T Disease Disease P16615 C318R Disease Disease P16615 P602L Disease Disease P98194 L341P Disease Disease P16615 G23E Disease Disease P98194 M641R Disease Disease P98194 P744R Disease Disease P98194 C490F Disease Disease P16615 N767S Disease Disease P98194 L318P Disease Disease P16615 L65S Disease Disease P16615 S765L Disease Disease P98194 P201L Disease Neutral P16615 C268F Disease Disease P16615 C875G Disease Disease P16615 G769R Disease Disease P16615 F675S Disease Neutral P98194 G309C Disease Disease P16615 E412G Disease Neutral P16615 G749R Disease Disease P16615 A803T Disease Disease P16615 A838P Disease Disease P98194 G645R Disease Disease P16615 V843F Disease Disease P16615 G211D Disease Disease P16615 S495F Disease Disease P09417 F212C Disease Disease P09417 G170S Disease Neutral P09417 G151S Disease Disease P09417 H158Y Disease Disease P09417 G23D Disease Disease P09417 P145L Disease Neutral P09417 L14P Disease Disease P09417 G149R Disease Disease P09417 W36R Disease Neutral P09417 G17R Disease Disease P09417 L74P Disease Disease P09417 Q66R Disease Neutral P09417 W108G Disease Disease P09417 Y150C Disease Disease P09417 S51T Neutral Neutral P09417 G18D Disease Disease P09417 G17V Disease Disease Q8N0W5 L220P Neutral Disease Q8N1N2 T189P Neutral Neutral Q8N1N2 V38A Neutral Neutral Q8NEZ2 I206F Neutral Neutral Q8NEZ2 I213V Neutral Neutral P12271 R151Q Disease Disease P12271 M226K Disease Neutral P12271 R234W Disease Disease Q13617 N109S Neutral Disease Q9Y222 V479I Neutral Neutral O00151 N175S Neutral Neutral P50479 G259C Neutral Disease P50479 V184I Neutral Neutral P50479 R118G Neutral Neutral Q6RI45 K1596E Disease Neutral Q6RI45 R1288K Neutral Neutral P54619 T89S Neutral Disease P54619 K329N Neutral Neutral O75131 T412M Neutral Neutral Q9HCH3 R582H Neutral Neutral Q99829 Q211R Neutral Neutral Q9HCH3 N33S Neutral Neutral Q9HCN3 A136T Neutral Neutral Q9HCN3 V310I Neutral Neutral Q9ULE4 A1042V Neutral Neutral Q9ULE4 N952S Neutral Neutral Q5TGY1 Q72K Neutral Neutral Q5TGY1 R478H Neutral Neutral Q96MY7 L622P Neutral Neutral Q96MY7 G11A Neutral Neutral Q9NVI7 G15D Neutral Neutral Q8WWH4 K216T Neutral Neutral Q96LB8 G192V Neutral Disease Q96LB8 D301N Neutral Neutral Q96LB8 Q92R Neutral Neutral Q96LB8 V213I Neutral Neutral Q96LB8 I13L Neutral Neutral P26639 G21D Neutral Neutral Q8NFL0 V233I Neutral Neutral Q96RV3 L809I Neutral Neutral Q96RV3 L814I Neutral Neutral O00116 L469P Disease Disease O00116 T309I Disease Disease O00116 R419H Disease Disease O95067 I395T Neutral Neutral O95067 M100T Neutral Neutral P48506 R127C Disease Disease P48506 P158L Disease Disease P48506 H370L Disease Disease P48506 P462S Neutral Disease P48506 L55S Neutral Disease Q06495 A48F Disease Neutral Q06495 V147M Disease Disease Q9Y3E2 G98A Neutral Neutral P35269 A3V Neutral Neutral Q13075 V535M Neutral Neutral Q9H3S1 D345H Disease Disease Q9H3S1 R713Q Disease Neutral Q9H3S1 F350C Disease Disease Q9H3S1 R510Q Neutral Disease Q9BU19 P230R Neutral Neutral Q96RT7 L567S Neutral Neutral Q8N6S4 T413S Neutral Neutral Q8TEK3 V1418L Neutral Neutral Q8TEK3 G1386S Neutral Neutral Q8TEK3 L726M Neutral Neutral Q9H7M9 E187D Neutral Neutral Q9Y490 R1919W Neutral Disease Q9Y490 S1227L Neutral Neutral Q9Y4G6 F2266L Neutral Neutral Q9Y4G6 A1148S Neutral Neutral Q9BSE4 T108A Neutral Neutral Q9BSE4 H200L Neutral Disease Q15011 R50H Neutral Neutral Q9BY32 P32T Disease Neutral Q9NWS9 P300S Neutral Neutral Q9NWS9 N192H Neutral Neutral Q96JB8 S44G Neutral Neutral P27694 T351A Neutral Neutral Q8NEP4 T88P Neutral Neutral Q8NEP4 C546G Neutral Disease Q8NEP4 G461S Neutral Neutral Q8WZA1 C490Y Disease Disease Q8WZA1 R265H Disease Neutral Q8WZA1 W425S Disease Disease Q8WZA1 V504I Neutral Neutral Q8WZA1 V623M Neutral Neutral Q8WZA1 C269Y Disease Disease Q8WZA1 R311Q Disease Disease Q8WZA1 S550N Disease Neutral Q8WZA1 P493R Disease Disease Q8WZA1 R442C Disease Disease Q8WZA1 E250V Neutral Neutral Q8WZA1 E223K Disease Neutral O95292 P56S Disease Disease Q8WVE0 T193N Neutral Neutral Q8IWY9 P1130L Disease Disease Q8IWY9 D1043V Disease Neutral Q8IWY9 R1042W Disease Neutral Q8IWY9 R714W Disease Neutral Q8IWY9 F868I Disease Disease Q8IWY9 V869M Disease Neutral Q8IWY9 E698K Disease Disease Q8IWY9 N599S Disease Neutral Q8IWY9 P672L Disease Disease Q7Z5K2 V124I Neutral Neutral Q9P243 G64R Neutral Neutral P42575 R441G Neutral Disease P42575 P178A Neutral Neutral P42575 V172L Neutral Neutral P23771 W274R Disease Disease Q96RP7 A467V Neutral Neutral Q96RP7 R353Q Neutral Neutral Q9NZH5 P44R Neutral Neutral P16473 A623I Disease Disease P16473 V597F Disease Disease P16473 D410N Disease Disease P16473 S281I Disease Disease P16473 N650Y Disease Disease P16473 F631C Disease Disease P16473 C672Y Disease Disease P16473 G431S Disease Disease P16473 V509A Disease Disease P16473 C390W Disease Disease P16473 I486F Disease Disease P16473 D619G Disease Disease P16473 R109Q Disease Neutral P16473 A623V Disease Disease P16473 F197I Disease Disease P16473 I630L Disease Disease P16473 L677V Disease Disease P16473 R528H Neutral Neutral P16473 R310C Disease Neutral P16473 L512R Disease Disease P16473 P162A Disease Neutral P16473 D727E Neutral Neutral P16473 N715D Disease Neutral P16473 F631L Disease Disease P16473 A703G Neutral Disease P16473 K183R Disease Neutral P16473 L467P Disease Disease P16473 D633E Disease Disease P16473 C600R Disease Disease P16473 T632I Disease Disease P16473 I568T Disease Neutral P16473 S281T Disease Disease P16473 L252P Disease Disease P16473 T477I Disease Disease P16473 P639S Disease Disease P16473 Q720E Neutral Neutral P16473 S281N Disease Disease P16473 C41S Disease Disease P16473 S505R Disease Disease P16473 R450H Disease Disease P16473 D633Y Disease Disease P16473 I486M Disease Disease P16473 D219E Disease Neutral P16473 G498S Disease Disease P16473 T632A Disease Disease P16473 M453T Disease Disease P16473 A647V Disease Disease P16473 I606M Neutral Neutral P16473 L629F Disease Disease P16473 S505N Disease Disease P16473 V597L Disease Disease P16473 M463V Disease Disease P16473 I167N Disease Disease P16473 P52T Neutral Neutral P16473 D633H Disease Disease P16473 K723M Disease Neutral P16473 D633A Disease Disease P16473 N670S Disease Disease P16473 F525L Disease Disease P16473 A553T Disease Disease Q9UJW0 F342L Neutral Neutral Q9UJW0 S438N Neutral Neutral Q9UJW0 Y263C Neutral Neutral Q9Y5P6 H126D Neutral Neutral Q9Y5P6 Q184R Neutral Neutral Q96IJ6 S21F Neutral Disease Q96IJ6 V156A Neutral Neutral P30039 R17C Neutral Disease P30039 H257R Neutral Neutral Q9P0K7 A44T Neutral Neutral Q8IY63 P847L Neutral Neutral O14522 Y412F Disease Neutral O14522 K218T Disease Neutral O14522 Y1351F Disease Neutral O14522 R1212W Disease Neutral O14522 M76V Neutral Neutral O14522 I395V Disease Neutral O14522 A1118P Disease Disease O14522 T1368M Disease Neutral O14522 A707T Disease Disease O14522 T605M Disease Neutral O14522 R790I Disease Neutral O14522 A707V Disease Disease O14522 N1128I Disease Disease O14522 Q987K Disease Disease O14522 V1269M Disease Disease O14522 V648G Disease Disease O14522 N510K Disease Neutral O14522 L708P Disease Disease O14522 F74S Disease Disease O14522 D927G Disease Neutral O14522 A29P Neutral Neutral O14522 R1346L Disease Disease O14522 Y280H Disease Neutral O14522 R453C Disease Disease O14522 M1259L Disease Disease O14522 F248S Disease Disease O14522 A209T Disease Disease Q02383 G368R Neutral Neutral Q02383 S274N Neutral Neutral Q02383 H279Y Neutral Disease Q02383 Q43K Neutral Neutral Q02383 T57A Neutral Neutral Q8N7U6 T380I Neutral Neutral Q8N7U6 I329V Neutral Neutral Q8N7U6 Q661P Neutral Neutral P01871 V216G Neutral Disease P01871 S192G Neutral Neutral Q00LT1 V30M Disease Neutral Q00LT1 R17C Neutral Neutral Q00LT1 C2Y Disease Neutral Q96RN1 S230N Neutral Disease Q96RN1 V73M Neutral Neutral Q96RN1 I639V Neutral Neutral Q96RN1 I148V Neutral Neutral O60840 R508Q Disease Disease O60840 G150R Disease Disease O60840 A1259T Neutral Disease O60840 F742C Disease Disease O60840 G261R Disease Disease O60840 L1497P Disease Disease O60840 P1489R Disease Disease O60840 I745T Disease Disease O60840 C1488R Disease Disease O60840 L849P Disease Disease O60840 L1068P Disease Disease O60840 C74R Disease Disease O60840 G1007R Disease Disease O60840 N735T Neutral Disease O60840 A917D Disease Disease O60840 G369D Disease Disease O60840 L1364H Disease Disease O60840 S229P Disease Neutral O60840 G663D Disease Disease O60840 P14L Neutral Neutral O60840 R1049W Disease Disease O60840 V624I Disease Neutral Q9BTV5 L232V Neutral Neutral Q9BZV3 P1013L Neutral Neutral Q9BZV3 T674I Neutral Neutral Q9BZV3 K344N Neutral Neutral Q8WY91 S121G Neutral Neutral O14967 V290I Neutral Neutral O14967 A160S Neutral Neutral Q8WXX7 A303S Neutral Neutral O95727 K321R Neutral Neutral O95727 A368G Neutral Neutral Q6IEG0 P45L Neutral Neutral Q9BYH8 T307S Neutral Neutral Q12934 D656E Neutral Neutral Q12934 G345S Neutral Neutral Q8WYK1 T1195M Neutral Neutral Q8WYK1 S452L Neutral Disease Q07820 A227V Neutral Neutral Q07820 E173D Neutral Neutral Q8N8R7 T180P Neutral Neutral O43303 I252M Neutral Neutral O43303 M375I Neutral Neutral P42702 S279P Disease Disease Q96FL8 V338I Neutral Neutral Q2TAC6 R471W Neutral Disease Q86TS9 G5V Neutral Disease Q86TS9 V19A Neutral Neutral Q4W5P6 V11A Neutral Neutral Q8IWW6 F442S Neutral Neutral Q9NV58 Q835H Neutral Neutral Q96AT1 I139M Neutral Neutral Q7Z5L4 A50V Neutral Neutral Q8IY81 E91Q Neutral Neutral Q8IY81 C424S Neutral Neutral Q02223 S81N Neutral Neutral Q02223 I65V Neutral Neutral Q02223 A54V Neutral Neutral Q02223 F75V Neutral Disease Q02223 A153T Neutral Neutral Q02223 C165S Neutral Neutral Q00889 K196E Neutral Neutral Q00889 I404S Neutral Neutral Q16557 L30P Neutral Neutral Q00889 L181M Neutral Neutral Q00888 V75L Neutral Disease Q16557 L23S Neutral Neutral Q00889 N185S Neutral Neutral Q00889 A258T Neutral Neutral Q00889 L257S Neutral Disease Q9UQ74 V349D Neutral Disease Q16557 N198T Neutral Neutral Q00889 K253N Neutral Neutral Q00889 R165L Neutral Neutral Q00889 I167T Neutral Neutral Q00889 L180W Neutral Neutral Q00889 R191S Neutral Disease Q00889 L155F Neutral Neutral Q8NHH9 N272S Neutral Neutral Q8NHH9 W18R Neutral Neutral Q8NHH9 D420H Neutral Neutral Q8IXX5 A80T Neutral Neutral Q8IXX5 R10M Neutral Neutral Q1AE95 M193V Neutral Neutral P15976 D218Y Disease Disease P15976 G208S Disease Disease P15976 R216Q Disease Disease P15976 V205M Disease Disease P15976 D218G Disease Disease Q0VAR9 G19S Neutral Neutral Q0VAR9 Y173C Neutral Neutral O60293 E1006K Neutral Neutral O60293 K1807R Neutral Neutral P25963 S32I Disease Neutral Q8N895 A739G Neutral Neutral Q96BD5 R347H Neutral Neutral Q9UBX0 N125S Neutral Neutral Q9UBX0 R160C Disease Disease Q5VYS4 R59G Neutral Neutral Q9P2N2 P727Q Neutral Neutral Q9P2N2 T190S Neutral Neutral Q99650 P936S Neutral Neutral Q99650 E527K Neutral Neutral Q99650 D553N Neutral Neutral Q99650 G210W Neutral Disease Q9H5Y7 L25F Neutral Neutral Q9H156 S601P Neutral Neutral Q9H5Y7 Q414R Neutral Neutral Q9H5Y7 P315R Neutral Neutral P20591 Q611H Neutral Neutral P20591 A381V Neutral Disease Q8IVW1 L170I Neutral Neutral Q75V66 C356R Disease Disease Q32M45 G115A Neutral Disease Q75V66 C356G Disease Disease Q4KMQ2 A128T Neutral Disease Q9H4F8 V82M Neutral Neutral Q9BQ51 F229S Neutral Neutral Q6PI26 S140I Neutral Neutral Q6PI26 S489N Neutral Neutral Q15007 E84D Neutral Neutral P00995 L14P Disease Disease P00995 L12F Disease Neutral P00995 R67H Neutral Neutral P00995 N34S Disease Neutral P00995 P55S Neutral Neutral Q08379 R890G Neutral Neutral Q5T8A7 M434T Neutral Neutral Q5T8A7 V98A Neutral Neutral Q5T8A7 K206E Neutral Neutral Q5T8A7 G576S Neutral Neutral Q5T8A7 R520H Neutral Neutral Q5T8A7 N834D Neutral Neutral Q5T8A7 R346K Neutral Neutral P48048 P110L Disease Neutral P48048 V72E Disease Disease P48048 M357T Disease Neutral P48048 G167E Disease Disease O60928 T175I Neutral Neutral P48048 S219R Disease Disease P48048 W99C Disease Disease P48048 A198T Disease Disease P48048 D108H Disease Disease P48048 N124K Disease Disease P48048 A214V Disease Disease P48048 V315G Disease Disease P48048 D74Y Disease Disease P48048 V122E Disease Disease Q8N2C3 H122R Neutral Neutral Q8TBR4 E116Q Neutral Neutral Q9NRD1 P201T Neutral Neutral Q5T1M5 A106T Neutral Neutral Q5T1M5 L434F Neutral Neutral Q5T1M5 H413Q Neutral Neutral Q96FL9 Q469K Neutral Disease P35520 L539S Disease Disease P35520 A226T Disease Neutral P35520 K102Q Disease Neutral P35520 G139R Disease Disease P35520 G151R Disease Disease P35520 G85R Disease Disease P35520 L101P Disease Disease P35520 C275Y Disease Disease P35520 L456P Disease Disease P35520 A114V Disease Disease P35520 R336C Disease Disease P35520 R121C Disease Disease P35520 D444N Disease Disease P35520 G305R Disease Disease P35520 I152M Disease Disease P35520 E131D Disease Disease P35520 V168M Disease Neutral P35520 G347S Disease Disease P35520 N228K Disease Disease P35520 S466L Disease Disease P35520 V180A Disease Neutral P35520 V320A Disease Disease P35520 T191M Disease Disease P35520 K384N Disease Disease P35520 A355P Disease Disease P35520 R125W Disease Disease P35520 A331E Disease Disease P35520 K384E Disease Disease P35520 R266K Disease Neutral P35520 T262R Disease Disease P35520 T262M Disease Disease P35520 I435T Disease Disease P35520 P290L Disease Disease P35520 S352N Disease Disease P35520 R336H Disease Disease P35520 P422L Disease Neutral P35520 R224H Disease Neutral P35520 K102N Disease Neutral P35520 C109R Disease Disease P35520 A155T Disease Disease P35520 S349N Disease Disease P35520 E176K Disease Disease P35520 V354M Disease Disease P35520 R125Q Disease Neutral P35520 D198V Disease Neutral P35520 G307S Disease Disease P35520 D234N Disease Neutral P35520 P145L Disease Disease P35520 T353M Disease Disease P35520 P78R Disease Neutral P35520 R491C Disease Neutral P35520 R369C Disease Disease P35520 E128D Disease Disease P35520 E302K Disease Neutral P35520 T434N Disease Neutral P35520 I143M Disease Neutral P35520 R369H Disease Neutral P35520 R121H Disease Disease P35520 E239K Disease Disease P35520 R58W Disease Disease P35520 R266G Disease Disease P35520 V534D Disease Disease P35520 H65R Disease Neutral P35520 A331V Disease Disease P35520 R439Q Disease Disease P35520 V371M Disease Disease P35520 M391I Disease Neutral P35520 E144K Disease Disease P35520 R379Q Disease Neutral P35520 M126V Disease Disease P35520 P49L Disease Disease P35520 V454E Disease Neutral P35520 R121L Disease Disease P35520 T257M Disease Disease P35520 C370Y Disease Neutral P35520 G148R Disease Disease P35520 L338P Disease Disease P35520 P88S Disease Disease P35520 I278T Disease Neutral P35520 C165Y Disease Disease P35520 G116R Disease Disease P35523 R496S Disease Disease P35523 A313T Disease Disease P35523 F161V Disease Neutral P35523 Y150C Disease Disease P35523 V563I Disease Neutral P35523 V286A Disease Disease P35523 Y261C Disease Disease P35523 R105C Disease Disease P35523 F167L Disease Neutral P35523 V327I Disease Neutral P35523 F708L Disease Neutral P35523 I556N Disease Disease P35523 G285E Disease Disease P35523 P480L Disease Disease P35523 Q552R Disease Disease P35523 I290M Disease Disease P35523 D136G Disease Disease P35523 E291K Disease Disease P35523 R317Q Disease Disease P35523 V236L Disease Disease P35523 V165G Disease Disease P35523 F307S Disease Disease P35523 F413C Disease Disease P35523 I329T Disease Neutral P35523 G230E Disease Disease P35523 A415V Disease Neutral P35523 R338Q Disease Neutral P35523 G482R Disease Disease P35523 G200R Disease Disease P35523 M485V Disease Disease P23415 Y307C Disease Disease P23415 K304E Disease Disease P23415 R299L Disease Disease P23415 I272N Disease Disease P23415 R428H Disease Disease P23415 Q294H Disease Neutral P23415 P278T Disease Disease P23415 R299Q Disease Disease P23415 R280H Disease Disease O75354 L138V Neutral Neutral O75354 S323N Neutral Neutral O75354 E202K Neutral Neutral O75354 S14N Neutral Neutral P20807 A160G Neutral Disease P20807 Q486E Disease Disease P20807 A702V Disease Neutral P20807 C137R Disease Disease P20807 A236T Neutral Neutral P20807 I502T Disease Disease P20807 G214S Disease Disease P20807 R489Q Disease Disease P20807 H334Q Disease Disease P20807 D77N Disease Disease P20807 G567W Disease Disease P20807 H774D Disease Neutral P20807 R448C Disease Disease P20807 T184M Disease Neutral P20807 R493W Disease Disease P20807 A798E Disease Neutral P20807 S744G Disease Neutral P20807 R437C Disease Disease P20807 R490Q Disease Disease P20807 R489W Disease Disease P20807 V4I Disease Neutral P20807 L182Q Disease Disease P20807 E217K Disease Disease P20807 R541Q Disease Disease P20807 I162L Disease Disease P20807 G222R Disease Disease P20807 R448G Disease Disease P20807 P319L Disease Neutral P20807 G234E Disease Disease P20807 S86F Disease Disease P20807 R490W Disease Disease P20807 V354G Disease Disease P20807 G441D Disease Disease P20807 G445R Disease Disease P20807 R572Q Disease Disease P20807 D705G Disease Disease P20807 P26L Disease Neutral P20807 Y336N Disease Disease P20807 R769Q Disease Disease P20807 S479G Disease Neutral P20807 S606L Disease Neutral P20807 Q638P Disease Neutral P20807 R698P Disease Disease P20807 E226K Disease Disease P20807 E107K Neutral Neutral P20807 G496R Disease Disease P20807 S215P Disease Disease P20807 R118G Disease Disease P20807 T232I Disease Disease P20807 D705H Disease Disease P20807 R448H Disease Disease P20807 L189P Disease Disease P20807 F731S Disease Disease P20807 R572W Disease Disease P20807 W360C Disease Disease P20807 P183L Disease Disease P20807 G21E Neutral Neutral P20807 R440W Disease Disease P20807 R748Q Disease Disease Q9Y5R8 R129G Disease Neutral Q96EK5 G66S Neutral Neutral Q9BUJ2 G91C Neutral Neutral Q8N7B9 G341R Neutral Disease Q8N7B9 M364I Neutral Neutral Q8N7B9 S370A Neutral Neutral Q9H9L3 N130S Neutral Neutral P11362 V795I Disease Neutral P11362 V102I Disease Neutral P11362 R250W Disease Disease P11362 E274G Disease Disease P11362 S346C Disease Disease P21802 Y340C Disease Disease P22607 I726F Neutral Disease P11362 M719R Disease Disease P11362 H621R Disease Disease P22455 T179A Neutral Neutral P22607 R621H Disease Disease P21802 G338E Disease Disease P11362 N330I Disease Disease P11362 C101F Disease Disease P21802 Y340H Disease Disease P21802 Y105C Disease Disease P21802 C342W Disease Disease P22455 D516N Neutral Disease P11362 D129A Disease Neutral P11362 Y99C Disease Disease P21802 S372C Disease Neutral P11362 A520T Disease Neutral P21802 A172F Disease Disease P21802 Y281C Disease Disease P21802 K641R Disease Disease P11362 R622Q Disease Disease P22607 D513N Disease Neutral P21802 G663E Disease Disease P21802 T341P Disease Disease P21802 Y301C Disease Neutral P21802 F276V Disease Disease P21802 S354Y Disease Disease P22607 E322K Disease Disease P21802 C342R Disease Disease P21802 A628T Disease Disease P11362 G237D Disease Disease P11362 R254Q Disease Disease P21802 G384R Disease Disease P11362 V607M Disease Disease P11362 C178S Disease Disease P11362 I538V Disease Neutral P11362 G703S Disease Disease P11362 G687R Disease Disease P21802 Y328C Disease Neutral P22607 A391E Neutral Neutral P11362 A167S Disease Neutral P11362 P722S Disease Disease P22607 S249C Disease Disease P22607 P250R Disease Disease P22607 A441T Neutral Neutral P22455 P136L Neutral Neutral P21802 G338R Disease Disease P11362 G270D Disease Disease P22607 K650M Disease Neutral P11362 Y339C Disease Disease P22607 N540K Disease Disease P11362 R622G Disease Disease P21802 R678G Disease Neutral P11362 G97D Disease Disease P22455 G388R Neutral Disease P21802 A344G Disease Disease P22607 N540S Disease Disease P22607 Y373C Disease Disease P11362 G703R Disease Disease P22607 G380R Disease Disease P22607 R248C Disease Disease P22607 G370C Disease Neutral P22455 V10I Neutral Neutral P11362 I300T Disease Neutral P21802 N549H Disease Neutral P11362 S332C Disease Neutral P21802 V359F Disease Disease P11362 S685F Disease Disease P21802 S252F Disease Disease P11362 P252R Disease Disease P21802 K526E Disease Neutral P21802 C342Y Disease Disease P21802 S347C Disease Disease P11362 A343V Disease Disease P11362 P283R Disease Disease P21802 K292E Disease Disease P21802 S267P Disease Disease P21802 W290R Disease Disease P21802 W290G Disease Disease P11362 I693F Disease Disease P11362 G48S Disease Disease P22607 S371C Disease Neutral P11362 L245P Disease Disease P22607 G65R Neutral Neutral P21802 Y375C Disease Neutral P11362 D224H Disease Disease P22607 A717T Neutral Neutral P22607 I538V Disease Neutral P22607 T338M Neutral Disease P21802 A648T Disease Disease P22607 G375C Disease Neutral P21802 P253R Disease Disease P11362 Y374C Disease Disease P11362 C277Y Disease Disease P11362 N724K Disease Disease P22607 F384L Neutral Neutral P11362 P745S Disease Disease P21802 C278Y Disease Disease P11362 W666R Disease Disease P21802 C342F Disease Disease P21802 C342G Disease Disease P21802 S351C Disease Disease P21802 D321A Disease Disease P21802 C342S Disease Disease P21802 I288S Disease Disease P11362 C381R Disease Disease P22607 D646N Neutral Disease P11362 V273M Disease Neutral P22607 K650E Disease Neutral P21802 P263L Disease Disease P11362 P722H Disease Disease P11362 P772S Disease Neutral P21802 E565G Disease Disease P22607 K650Q Disease Neutral P22607 N540T Disease Neutral P21802 S252L Disease Disease P21802 A362S Disease Neutral P21802 W290C Disease Disease P11362 R78C Disease Disease P21802 A337P Disease Disease P21802 N331I Disease Disease P21802 Q289P Disease Disease P21802 S252W Disease Disease P21802 C278F Disease Disease P21802 A344P Disease Disease P21802 S354C Disease Disease O94761 E301K Neutral Neutral O94761 G1105S Neutral Neutral O94761 R1021Q Neutral Neutral O94761 V799M Neutral Neutral O94761 S1148F Neutral Neutral O94761 P964T Neutral Neutral O94761 G1113R Neutral Neutral O94761 G189S Neutral Neutral O94761 S523T Neutral Neutral O94761 P441S Neutral Neutral O94761 R1021W Disease Neutral O94761 E976K Neutral Neutral O94761 R355Q Neutral Neutral O94761 R1005Q Neutral Neutral O94761 R1106H Neutral Neutral O94761 E71G Neutral Neutral O94761 P92S Neutral Neutral O94761 R1004W Neutral Neutral O94761 P793S Neutral Neutral O94761 A273T Neutral Neutral O94761 Q54R Neutral Neutral O94761 R522C Neutral Neutral O94761 G1105D Neutral Neutral O94761 A1045T Neutral Neutral O94761 E267D Neutral Neutral O94761 R522H Neutral Neutral O94761 P591L Neutral Disease O94768 S320F Neutral Neutral P19544 H377R Disease Disease P19544 R366C Disease Neutral P19544 M342R Disease Neutral P19544 S223N Disease Neutral P19544 H377Y Disease Neutral P19544 D396N Disease Neutral P19544 C360G Disease Neutral P19544 H373Q Disease Neutral P19544 C330Y Disease Neutral P19544 C388F Disease Neutral P19544 L398P Disease Neutral P19544 F392L Disease Neutral P19544 C385R Disease Neutral P19544 C355Y Disease Neutral P19544 R366H Disease Neutral P19544 R394W Disease Disease P19544 G253A Disease Neutral P19544 D396G Disease Neutral P19544 R394Q Disease Neutral P19544 F383L Disease Neutral P19544 R312Q Disease Disease P19544 P181S Disease Neutral P19544 H373Y Disease Neutral Q9UPV0 Q1119R Neutral Neutral Q9UPV0 T988S Neutral Neutral Q9UPV0 S94N Neutral Neutral P34810 A340T Neutral Neutral P34810 Q254K Neutral Neutral Q8IUG5 R1195Q Disease Neutral Q8IUG5 G2295C Disease Neutral Q8IUG5 R379Q Disease Neutral Q8IUG5 P1238Q Disease Neutral Q8IUG5 A835G Disease Neutral Q8IUG5 E1708K Disease Neutral Q8IUG5 Q2347R Neutral Neutral Q8IUG5 R2381H Disease Neutral Q8IUG5 D2554E Disease Neutral Q8IUG5 E1715D Disease Neutral Q8IUG5 P1238T Disease Neutral Q8IUG5 W389C Disease Neutral Q8IUG5 K347N Disease Neutral Q8IUG5 T590M Disease Neutral Q8IUG5 A1970E Disease Neutral Q8IUG5 R1095L Disease Disease Q8IUG5 G234V Disease Neutral Q8IUG5 R661W Disease Disease Q9P2D0 V1065I Neutral Neutral Q9P2D0 A1185V Neutral Neutral O15374 N264H Neutral Neutral P46527 V109G Neutral Neutral P46527 R15W Neutral Neutral Q8NDD1 L28V Neutral Neutral Q9H9S0 K82N Neutral Neutral P13051 F251S Disease Disease Q8N6C8 L107R Neutral Disease Q8N6C8 P3S Neutral Neutral Q8N6C8 Y301H Neutral Neutral Q16690 E154D Neutral Neutral P28562 A56T Neutral Neutral P28562 Y187H Neutral Neutral Q9BTE0 C56R Neutral Neutral Q8NG50 C127W Neutral Neutral Q8NG50 H32R Neutral Neutral O00142 I53M Disease Neutral O00142 I212N Disease Disease O00142 R183W Disease Disease O00142 R192K Disease Disease O00142 T108M Disease Disease O00142 T64M Disease Disease O00142 H121N Disease Neutral Q8IUE1 V197I Neutral Neutral Q16595 R165C Disease Disease Q16595 G130V Disease Disease Q16595 L182F Disease Disease Q16595 W155R Disease Disease Q16595 I154F Disease Disease Q16595 D122Y Disease Disease Q16595 L106S Disease Disease Q16595 L198R Disease Disease P12036 E811A Neutral Neutral Q9Y2C3 R144H Neutral Disease Q9Y2C3 M85T Neutral Neutral Q8N0W7 A142V Neutral Neutral P54105 M218T Neutral Neutral P54105 Q20H Neutral Neutral Q96DT7 I174M Neutral Neutral Q96DT7 T50P Neutral Neutral Q96QF7 T662I Neutral Neutral Q6IPM2 A546V Neutral Neutral Q6IPM2 H101N Neutral Neutral Q6IPM2 T690M Neutral Neutral Q6IPM2 R587H Neutral Neutral Q6IPM2 T596A Neutral Neutral Q6IPM2 L666V Neutral Neutral Q05315 V28A Neutral Neutral Q08043 Q523R Neutral Neutral Q08043 E635A Neutral Disease P35609 M604V Neutral Neutral O43707 S262P Disease Disease O43707 K255E Disease Disease O43707 T259I Disease Disease Q8N8B7 S163L Neutral Neutral Q08257 P66S Neutral Disease Q08257 I176V Neutral Neutral P00558 D285V Disease Disease P00558 E252A Disease Neutral P00558 C316R Disease Disease P00558 D164V Disease Disease P00558 T352N Neutral Disease P00558 G158V Disease Disease P00558 R206P Disease Disease P04075 D129G Disease Disease P05062 E207Q Neutral Disease P05062 P185R Disease Disease P05062 C135R Disease Disease P05062 A150P Disease Disease P05062 I268N Neutral Disease P05062 R134S Neutral Disease P05062 N335K Disease Disease P05062 L257P Disease Disease P05062 A338V Disease Disease P05062 V222F Disease Disease P05062 L229P Disease Disease P05062 I74T Disease Disease P05062 R304Q Disease Disease P05062 A175D Disease Disease P05062 R304W Disease Disease Q68G75 P25S Neutral Neutral P80108 D275E Neutral Neutral P80108 V461M Neutral Neutral P80108 G396S Neutral Neutral P80108 V30I Neutral Neutral P80108 T698I Neutral Neutral P80108 M694V Neutral Neutral P80108 L17V Neutral Neutral Q9HC23 G32R Disease Disease Q9HC23 R73C Disease Disease Q9Y3D7 Q114K Neutral Neutral P11473 L230V Neutral Neutral O75469 R148Q Neutral Neutral O75469 P27S Neutral Neutral O75469 R381W Neutral Disease O75469 G36R Neutral Disease O75469 A370T Neutral Neutral O75469 E18K Neutral Disease O75469 R122Q Neutral Disease O75469 I403V Neutral Neutral P11473 T362I Neutral Neutral O75469 R98C Neutral Disease Q9H9Y6 S295L Neutral Neutral P02549 R28C Disease Neutral P02549 Q471P Disease Disease P02549 G46V Disease Neutral P02549 L260P Disease Disease P02549 R34W Disease Disease P02549 R41W Disease Disease P02549 R1330I Neutral Disease P02549 D152N Neutral Neutral P02549 I24S Disease Disease P02549 R28S Disease Neutral P02549 R28H Disease Neutral P02549 R28L Disease Neutral P02549 A766T Neutral Neutral P02549 V31A Disease Disease P02549 K48R Disease Neutral P02549 R45T Disease Disease P02549 L49F Disease Disease P02549 L207P Disease Disease P02549 S261P Disease Disease P02549 A1163S Neutral Neutral P02549 I809V Neutral Neutral P02549 T853R Neutral Neutral P02549 D791E Disease Neutral P02549 H469P Disease Disease P02549 A957V Neutral Disease P02549 R701H Neutral Disease P02549 R45S Disease Disease P02549 R1568C Neutral Disease P02549 G151D Disease Neutral P02549 L1857V Neutral Neutral P02549 S109F Neutral Neutral P02549 A970D Neutral Neutral Q9H2G9 R196Q Neutral Neutral Q9H2G9 Q40R Neutral Neutral Q9BWS9 A338V Neutral Neutral Q9BWS9 R331Q Neutral Neutral P59095 E159K Neutral Neutral Q9HBL8 P252L Neutral Disease Q9HBL8 T23I Neutral Neutral Q15084 K214R Neutral Neutral Q8TE85 D55E Neutral Disease Q5TF39 S93P Neutral Disease P26678 R9C Disease Neutral P02765 T256S Neutral Neutral P02765 D276N Neutral Neutral P02765 T248M Neutral Neutral P02765 R317C Neutral Disease Q96MC2 W399R Neutral Neutral Q96MC2 K357E Neutral Neutral Q96MC2 V633F Neutral Neutral Q96MC2 S702I Neutral Neutral Q8N1K5 I630V Neutral Neutral Q8N1K5 V284G Neutral Neutral P06865 G250S Disease Disease P06865 L39R Disease Disease P06865 S279P Disease Neutral P06865 L484Q Disease Disease P06865 G454S Disease Disease P06865 C458Y Disease Disease P06865 R170W Disease Disease P06865 K197T Disease Disease P06865 W420C Disease Disease P06865 D258H Disease Disease P06865 V391M Disease Neutral P06865 F211S Disease Disease P06865 P25S Disease Disease P06865 E482K Disease Disease P06865 M301R Disease Disease P06865 R252L Disease Disease P06865 R170Q Disease Disease P06865 I335F Disease Disease P06865 R499H Disease Disease P06865 W474C Disease Disease P06865 R499C Disease Disease P06865 R504C Disease Disease P06865 R166G Disease Disease P06865 V192L Disease Neutral P06865 G269S Disease Neutral P06865 H204R Disease Disease P06865 R252H Disease Disease P06865 G250D Disease Disease P06865 N399D Neutral Neutral P06865 G455R Disease Disease P06865 R504H Disease Disease P06865 R178H Disease Disease P06865 S210F Disease Neutral P06865 V436I Neutral Neutral P06865 S226F Disease Neutral P06865 R178C Disease Disease P06865 N295S Disease Neutral P06865 N196S Disease Neutral P06865 V200M Disease Disease P06865 L127R Disease Disease P06865 L127F Disease Neutral P06865 W485R Disease Disease P06865 R178L Disease Disease P06865 Y180H Disease Disease P06865 G269D Disease Neutral P06865 D314V Disease Disease O15417 E492G Neutral Neutral O15417 Q330R Neutral Neutral O15417 K469E Neutral Neutral O15417 R784K Neutral Neutral O15417 W509R Neutral Neutral Q13642 C224W Disease Disease Q13642 W122S Disease Disease P60896 D17G Neutral Neutral O15060 P689A Neutral Neutral P07099 R454Q Neutral Neutral P07099 Y113H Neutral Neutral P07099 L452Q Neutral Disease P07099 H139R Neutral Neutral P07099 T396I Neutral Disease P07099 R49C Neutral Disease P07099 L260P Neutral Disease P07099 R43T Neutral Neutral P07099 E44Q Neutral Neutral P07099 T408M Neutral Neutral P07099 V285L Neutral Neutral Q92733 P136S Neutral Neutral Q8IZJ4 Q24R Neutral Neutral Q8IZJ4 V378A Neutral Neutral Q8IZJ4 M342R Neutral Neutral Q8IZJ4 H241Y Neutral Neutral Q9UNE0 R89H Disease Neutral Q9UNE0 V370A Neutral Neutral Q9UNE0 C87R Disease Disease Q9UNE0 R420Q Disease Neutral P50895 R282H Neutral Neutral P50895 T539A Neutral Neutral P50895 V196I Neutral Neutral P50895 M204K Neutral Neutral P50895 R77H Neutral Neutral P50895 V381I Neutral Neutral P50895 K451Q Neutral Neutral P50895 Q581L Neutral Neutral P50897 I134T Neutral Neutral P50897 L219Q Disease Disease P50897 G250V Disease Disease P50897 G108R Disease Disease P50897 T75P Disease Neutral P50897 Y247H Disease Disease P50897 D79G Disease Disease P50897 H39Q Disease Disease P50897 Q177E Disease Disease P50897 G42E Disease Disease P50897 R122W Disease Disease P50897 V181L Disease Disease P50897 Y109D Disease Disease P50897 V181M Disease Neutral P08865 R117W Neutral Neutral P56556 A9V Neutral Neutral P10451 R301H Neutral Neutral Q9P2P1 E997K Neutral Neutral Q9P2P1 A659V Neutral Neutral Q9P2P1 I1551V Neutral Neutral Q9P2P1 A978T Neutral Neutral Q9P2P1 T457M Neutral Neutral Q3T906 A662G Neutral Neutral Q3T906 D407A Disease Disease Q3T906 K1236M Disease Neutral Q3T906 I348L Neutral Disease Q3T906 K4Q Disease Neutral Q9GZR5 I267T Neutral Neutral Q9GZR5 M299V Neutral Neutral Q495W5 S51A Neutral Neutral P00325 N57K Neutral Neutral P00326 I350V Neutral Neutral P08319 I374V Neutral Neutral P00325 R48H Neutral Neutral P00325 R370C Neutral Disease P11766 V309I Neutral Neutral P28332 C102G Neutral Disease P00325 T60S Neutral Neutral P00326 R272Q Neutral Neutral P08319 R318H Neutral Disease P11766 L163S Neutral Neutral P00326 P166S Neutral Disease P40394 G80A Neutral Disease P08319 V309I Neutral Neutral P00326 R48H Neutral Neutral P00326 P352T Neutral Disease P28332 I114V Neutral Neutral Q9H0Y0 P220H Neutral Neutral Q9H0Y0 T212M Neutral Neutral Q9H0Y0 S62P Neutral Neutral Q86X51 R470K Neutral Neutral Q9NZI5 V397I Neutral Neutral Q9NZI5 N191S Neutral Neutral P50461 W4R Disease Neutral Q9HBR0 A831G Neutral Neutral Q9NUM4 T185S Neutral Neutral P18846 P191A Neutral Disease Q9Y3L3 P511L Neutral Neutral Q9Y3L3 S656F Neutral Neutral Q9Y3L3 L431P Neutral Disease Q9NWS0 P287L Neutral Neutral Q9NWS0 V224I Neutral Neutral Q9NWS0 M9L Neutral Neutral Q9NWS0 D230E Neutral Neutral Q9NWS0 G10E Neutral Neutral Q9UM54 C442Y Disease Neutral Q9UM54 E216V Disease Neutral Q9UM54 H246R Disease Disease P27816 E441Q Neutral Neutral P27816 S367P Neutral Neutral P27816 D409G Neutral Neutral P27816 S427Y Neutral Neutral P27816 I994V Neutral Neutral P27816 R23Q Neutral Neutral P27816 P366L Neutral Neutral P27816 I628V Neutral Neutral Q96JH8 G884S Neutral Neutral Q14264 T90I Neutral Neutral Q14264 N481S Neutral Neutral Q14264 Y236C Neutral Neutral Q14264 N569S Neutral Neutral Q14264 C192Y Neutral Disease Q14264 L522P Neutral Disease Q8WY64 N342S Neutral Neutral Q99497 E163K Neutral Disease Q99497 A104T Disease Disease Q99497 D149A Disease Disease Q99497 E64D Disease Neutral Q99497 A171S Neutral Neutral Q99497 M26I Disease Disease Q99497 G150S Neutral Disease Q99497 L166P Disease Disease Q99497 R98Q Neutral Neutral Q13895 E103K Neutral Neutral P35346 T333M Neutral Neutral Q969F8 R297L Disease Neutral P35346 L48M Neutral Disease P35372 D274N Neutral Neutral Q969F8 L148S Disease Neutral P35346 L251S Neutral Neutral P35372 N152D Neutral Disease P35372 R260H Neutral Disease P35346 G37R Neutral Disease P35346 A52V Neutral Neutral P41145 D374N Neutral Neutral Q969F8 C223R Disease Disease P35372 N40D Neutral Disease P35372 R265C Neutral Neutral P35372 A6V Neutral Neutral Q969F8 L364H Neutral Neutral P35346 P335L Neutral Neutral P35346 P109S Neutral Neutral P35346 R339K Neutral Neutral P35346 W105R Neutral Disease P41143 F27C Neutral Neutral P35372 S147C Neutral Neutral Q99571 S242G Neutral Neutral Q99571 A6S Neutral Neutral Q8NI17 D155N Neutral Neutral Q8NI17 S497N Neutral Neutral P30042 V148M Neutral Neutral P30042 V6A Neutral Neutral P30042 L248V Neutral Disease Q5SZI1 N134T Neutral Neutral Q09470 R204H Neutral Neutral Q09470 A242P Neutral Disease Q09470 S342I Disease Disease Q09470 V408A Disease Disease Q09470 T226R Disease Disease Q09470 T226A Disease Neutral Q09470 F184C Disease Neutral Q09470 I177R Disease Disease Q09470 P244H Neutral Disease Q09470 V404I Disease Neutral Q09470 T226K Neutral Neutral Q09470 L329I Disease Disease Q09470 E325D Disease Disease Q09470 T226M Disease Disease Q09470 V174F Disease Disease Q09470 F249I Disease Disease Q09470 R239S Disease Disease Q86X19 G26S Neutral Neutral P05161 S83N Neutral Disease P15104 R341C Disease Disease P15104 R324C Disease Disease Q8NI35 R1282H Neutral Neutral Q8NI35 E780K Neutral Neutral Q8NI35 G1178S Neutral Neutral Q8NI35 V1360L Neutral Neutral Q8NI35 I400V Neutral Neutral Q8NI35 Q599H Neutral Neutral Q8NI35 G303R Neutral Disease Q8NI35 I870M Neutral Neutral Q8NI35 E362A Neutral Neutral Q8NI35 C744R Neutral Neutral Q8NI35 E779K Neutral Neutral Q8NI35 A1504P Neutral Disease O60890 A45T Neutral Neutral O60890 T301M Neutral Neutral O60890 M693I Neutral Neutral Q9UM13 R46Q Neutral Neutral P15927 Y14S Neutral Disease Q13156 A33T Neutral Neutral P15927 G15R Neutral Neutral P15927 N203S Neutral Neutral Q8IYL3 A101S Neutral Neutral Q8IYL3 T53R Neutral Neutral Q9NWZ3 S98R Neutral Neutral Q9NWZ3 A428T Neutral Neutral Q9NWZ3 I5V Neutral Neutral Q9NWZ3 H390R Neutral Neutral Q9NWZ3 R391H Neutral Disease Q9NWZ3 M355V Neutral Disease Q9BV10 R146Q Disease Disease Q9BV10 L158P Disease Disease Q9BV10 T67M Disease Disease Q9BV10 G101R Disease Disease Q9BV10 F142V Disease Disease Q9BV10 I393V Neutral Neutral Q9UJA9 I171V Neutral Neutral Q9UJA9 R39P Neutral Disease Q9UJA9 L6I Neutral Neutral Q9P2K3 K42R Neutral Neutral Q8TB45 S389N Neutral Neutral Q8TB45 S204N Neutral Neutral Q8TB45 N148S Neutral Neutral Q96AN5 D143N Neutral Neutral Q9GZZ0 A296T Neutral Neutral Q5JST6 E208K Neutral Neutral Q5JST6 N31S Neutral Neutral Q5JST6 S430Y Neutral Neutral Q5JST6 E507Q Neutral Neutral P36956 A309T Neutral Neutral P36956 R746H Neutral Neutral P36956 V580M Neutral Neutral P36956 N306S Neutral Neutral P36956 V417M Neutral Neutral P36956 S834L Neutral Disease P36956 T1000A Neutral Neutral P36956 A1008P Neutral Neutral Q7Z408 L2661R Neutral Disease Q7Z408 R2096K Neutral Neutral Q7Z408 M2554V Neutral Neutral Q7Z408 S3406F Neutral Neutral Q7Z408 A2117V Neutral Disease Q7Z408 L167P Neutral Neutral Q7Z408 H538R Neutral Neutral O00423 P556S Neutral Neutral O00423 A377V Neutral Neutral O00423 H552N Neutral Disease Q8N9R8 T37A Neutral Neutral Q5R3I4 F243L Neutral Neutral P49753 H475R Neutral Neutral Q08648 R77Q Neutral Neutral Q16720 I198M Neutral Neutral P20020 M267R Neutral Disease O75716 E55K Neutral Neutral O75716 H41R Neutral Neutral O75716 I77V Neutral Neutral O75716 P277L Neutral Disease O75716 R266W Neutral Disease Q14624 L669Q Neutral Neutral Q14624 N85I Neutral Disease Q14624 P698T Neutral Neutral Q14624 L791P Neutral Neutral Q14624 I86N Neutral Disease Q14624 I714M Neutral Neutral Q9NY15 M2506T Neutral Neutral Q5H9R4 R188G Neutral Neutral Q9UPS8 Q20R Neutral Neutral Q9UPS8 V1304I Neutral Neutral Q9UPS8 F1513L Neutral Neutral Q9UJJ7 L247P Neutral Disease Q9UJJ7 E124Q Neutral Neutral P43320 A65S Neutral Neutral O75943 L557R Neutral Disease O75943 V32I Neutral Neutral O75943 R487L Neutral Disease O75943 K535E Neutral Neutral P54368 A147V Neutral Neutral P54368 S53F Neutral Neutral P54368 G44D Neutral Neutral P54368 S50F Neutral Neutral P54368 R32L Neutral Neutral Q9BSW2 A98T Neutral Neutral Q9BSW2 H136P Neutral Neutral Q9BSW2 H212Q Neutral Neutral Q9BSW2 A128V Neutral Neutral Q9BSW2 E154K Neutral Neutral Q9BSW2 R7G Neutral Neutral O15529 C45R Neutral Neutral O15529 V256A Neutral Neutral O15529 V227L Neutral Neutral P40238 A58V Neutral Neutral P40238 E168K Neutral Neutral Q96PV4 N107H Neutral Neutral Q96PV4 R349W Neutral Neutral O75880 P174L Disease Disease O75880 P58S Neutral Neutral O75145 A563S Neutral Neutral Q13136 V71I Neutral Neutral Q5TCZ1 K659Q Neutral Neutral Q5TCZ1 R1035Q Neutral Neutral Q8NEQ5 G3S Neutral Neutral Q7Z443 S211P Neutral Neutral Q7Z443 A471D Neutral Disease Q7Z443 T429S Neutral Neutral Q7Z443 V593M Neutral Neutral Q7Z443 H571Q Neutral Neutral Q7Z443 Y1474C Neutral Disease Q7Z443 I120F Neutral Neutral Q7Z443 V903I Neutral Neutral Q7Z443 K274E Neutral Neutral Q7Z443 S1176R Neutral Disease Q6P1Q9 N129H Neutral Neutral Q6P1Q9 C124R Neutral Neutral Q6P1Q9 I266V Neutral Neutral Q6P1Q9 E169K Neutral Neutral P55851 S282C Neutral Neutral P55851 R154Q Neutral Neutral P55851 R76Q Neutral Disease P55851 A55V Neutral Neutral P25874 A64T Neutral Neutral P55851 A268G Neutral Neutral P55916 V102I Neutral Neutral P25874 M229L Neutral Neutral Q9BUK6 T324I Neutral Neutral Q96GZ6 A62T Neutral Neutral Q96H96 Y247C Disease Disease Q5T2T1 K322R Neutral Neutral Q9NRE2 R113S Neutral Neutral Q9NRE2 A681T Neutral Neutral Q5T681 E121D Neutral Neutral Q7KZN9 R217W Disease Disease Q7KZN9 S344P Disease Disease Q3MIN7 V164A Neutral Neutral Q3MIN7 R615C Neutral Neutral Q3MIN7 P162H Neutral Neutral P17812 S571I Neutral Neutral Q9NXF7 N45S Neutral Neutral Q9NXF7 T129I Neutral Neutral Q9H714 G152R Neutral Neutral Q58DX5 I128M Neutral Neutral Q58DX5 S677L Neutral Neutral Q58DX5 S385P Neutral Disease Q58DX5 R622P Neutral Neutral Q58DX5 M194T Neutral Neutral Q58DX5 G68S Neutral Neutral O15381 C359G Neutral Disease Q7Z5Q5 M310L Neutral Neutral Q7Z5Q5 R425C Neutral Disease Q7Z5Q5 S502G Neutral Neutral Q7Z5Q5 G336S Neutral Neutral Q7Z5Q5 F711L Neutral Disease Q7Z5Q5 Q121H Neutral Neutral Q7Z5Q5 P315S Neutral Neutral Q7Z5Q5 R201G Neutral Neutral P02679 G191R Neutral Disease P02679 Y140H Neutral Neutral P02679 M410V Neutral Disease Q96DN5 V709F Neutral Neutral Q96DN5 R414H Neutral Neutral Q8IYX1 R113Q Neutral Neutral O95801 S47T Neutral Neutral Q96BD8 V91I Neutral Neutral Q9UNQ0 F489L Neutral Disease Q9UNQ0 S248P Neutral Disease Q9UNQ0 N590Y Neutral Neutral Q9UNQ0 I206L Neutral Disease Q9UNQ0 A528T Neutral Neutral Q9UNQ0 Q141K Neutral Disease Q9UNQ0 T316P Neutral Disease Q9UNQ0 F208S Neutral Disease Q9UNQ0 Q166E Neutral Disease Q9UNQ0 D620N Neutral Neutral Q9UNQ0 F571I Neutral Neutral Q9UNQ0 F431L Neutral Disease Q9UNQ0 D296H Neutral Disease Q9UNQ0 V12M Neutral Neutral Q96HZ4 R218Q Neutral Neutral Q13635 A443G Disease Neutral Q13635 E1242K Disease Neutral Q13635 S1132P Disease Disease Q13635 F376S Disease Disease Q13635 V751G Disease Disease Q13635 P1282L Neutral Neutral Q13635 A393T Disease Neutral Q13635 G1069R Disease Disease Q13635 G509R Disease Disease Q13635 T230P Disease Disease Q13635 D513Y Disease Disease Q13635 R1114W Disease Disease Q13635 T1052M Disease Neutral Q13635 S1132Y Disease Disease Q13635 L175P Disease Disease Q13635 S827G Disease Neutral Q13635 G509V Disease Disease Q13635 E1438D Disease Neutral Q13635 V908G Disease Disease Q13635 V829M Disease Neutral Q13635 T728M Disease Neutral Q13635 P1315L Neutral Neutral Q13635 T1195S Neutral Neutral P55201 G1117E Neutral Disease P48382 R197Q Neutral Neutral P48382 P409R Neutral Neutral P48382 P499S Neutral Neutral Q16586 V196I Disease Neutral Q16586 V175A Disease Neutral Q16586 V247M Disease Neutral Q16586 L158F Disease Neutral Q16586 I103T Disease Disease Q16586 Y62H Disease Disease Q16586 I124T Disease Neutral Q16586 G91R Disease Disease Q16586 R34C Disease Neutral Q16586 L89P Disease Disease Q16586 E137G Disease Neutral Q16586 R98H Disease Neutral Q16586 L31P Disease Disease Q16586 G68E Disease Disease Q16586 R74W Disease Neutral Q16586 L173P Disease Disease Q16586 A93V Disease Neutral Q16586 R98C Disease Neutral Q16586 R284C Disease Disease Q16586 E137K Disease Disease Q16586 R77C Disease Disease Q16586 P30L Disease Neutral Q16586 V242A Disease Neutral Q16586 P228Q Disease Neutral Q16586 D97G Disease Neutral Q16586 P205H Disease Neutral Q16586 R34H Disease Neutral O14613 I191F Neutral Neutral O14613 N176S Neutral Neutral Q92685 R171Q Disease Disease Q92685 G118D Disease Disease Q92685 I107V Neutral Neutral Q9NWH9 V235L Neutral Neutral P58340 P226T Neutral Neutral O60333 Q98L Disease Disease Q9H0K1 T458I Neutral Neutral Q9H0K1 R809Q Neutral Neutral Q9H0K1 P825L Neutral Neutral Q9HC36 I185V Neutral Neutral Q9HC36 G45E Neutral Neutral Q9HC36 E326Q Neutral Neutral Q9HC36 A8S Neutral Neutral Q8IYA6 L19F Neutral Neutral Q8IYA6 P379A Neutral Neutral Q8IYA6 L614S Neutral Neutral Q8IYA6 S62N Neutral Neutral Q8IYA6 S263R Neutral Neutral Q8IYA6 E706D Neutral Neutral Q8IYA6 I375V Neutral Neutral Q8IYA6 S519G Neutral Neutral Q8IYA6 K26R Neutral Neutral Q8IYA6 T104I Neutral Neutral Q16568 S66T Neutral Neutral Q86SQ9 V253M Neutral Neutral Q8TBY9 L450F Neutral Neutral Q8TBY9 T388M Neutral Neutral Q8TBY9 E66G Neutral Neutral Q969F0 A10V Neutral Neutral O75132 V420I Neutral Neutral Q96CM8 V316M Neutral Neutral Q96CM8 G75V Neutral Disease Q9NZN9 C239R Disease Disease Q9NZN9 D90H Neutral Disease P04279 S79T Neutral Neutral P04279 R372L Neutral Neutral Q8N5T2 S241G Neutral Neutral Q8N5T2 F509S Neutral Neutral O00255 H322R Disease Disease O00255 G286R Disease Neutral O00255 K135I Disease Disease O00255 E184K Disease Disease O00255 E184Q Disease Disease O00255 A342D Disease Disease O00255 A342P Disease Disease O00255 L419P Disease Disease O00255 R532C Disease Neutral O00255 Y358D Disease Disease O00255 L22R Disease Disease O00255 L291P Disease Disease O00255 S258W Disease Neutral O00255 P282H Disease Neutral O00255 C246R Disease Disease O00255 E45K Disease Disease O00255 H139P Disease Disease O00255 W346R Disease Disease O00255 A546T Neutral Neutral O00255 V220M Disease Neutral O00255 L272P Disease Disease O00255 V245F Disease Disease O00255 L173P Disease Disease O00255 R420P Disease Disease O00255 I377M Disease Neutral O00255 L269P Disease Neutral O00255 C246F Disease Disease O00255 C426Y Disease Disease O00255 H139Y Disease Neutral O00255 F452S Disease Disease O00255 Q265P Disease Neutral O00255 T316P Disease Neutral O00255 R319P Disease Disease O00255 E364K Disease Neutral O00255 A416P Disease Disease O00255 D423N Disease Disease O00255 A181P Disease Disease O00255 D423H Disease Neutral O00255 W188S Disease Disease O00255 A314P Disease Disease O00255 P549S Disease Neutral O00255 G42D Disease Disease O00255 A330P Disease Neutral O00255 H139R Disease Neutral O00255 D177Y Disease Disease O00255 S160F Disease Neutral O00255 E26K Disease Neutral O00255 L449P Disease Disease O00255 A165P Disease Neutral O00255 G310D Disease Neutral O00255 P325L Disease Disease O00255 F144V Disease Neutral O00255 L228P Disease Disease O00255 S258P Disease Neutral O00255 D362H Disease Neutral O00255 W441C Disease Disease O00255 E260K Disease Neutral O00255 P378S Disease Disease O00255 S432R Disease Neutral O00255 A289E Disease Neutral O00255 A347P Disease Disease O00255 R360W Disease Disease O00255 R234L Disease Neutral O00255 V167F Disease Disease O00255 C170R Disease Disease O00255 W441R Disease Disease O00255 P325R Disease Disease O00255 E279A Disease Neutral O00255 P545S Disease Neutral O00255 C246Y Disease Disease O00255 V189E Disease Disease O00255 H186R Disease Disease O00255 I353N Disease Disease O00255 S560R Disease Neutral O00255 A390V Disease Neutral O00255 L39W Disease Neutral O00255 S159I Disease Neutral O00255 T349R Disease Neutral O00255 G110E Disease Neutral O00255 A169D Disease Disease O00255 G161D Disease Neutral O00255 P12L Disease Disease O00255 H139D Disease Disease O00255 R98L Disease Neutral O00255 G230R Disease Disease O00255 A289P Disease Neutral O00255 A247V Disease Neutral O00255 W188R Disease Disease O00255 R176Q Neutral Neutral O00255 A373D Disease Disease O00255 E184D Disease Neutral O00255 L264R Disease Disease O00255 S560N Disease Neutral O00255 A165T Disease Neutral O00255 D158V Disease Disease O00255 E45G Disease Neutral O00255 W428S Disease Disease O00255 H322Y Disease Disease O15265 P663S Neutral Neutral O15265 K264R Neutral Neutral O15265 V862M Neutral Neutral Q92535 P266S Neutral Neutral Q9NS56 P812R Neutral Neutral Q9NS56 A154T Neutral Neutral Q9NS56 N749D Neutral Neutral Q9NS56 E517K Neutral Neutral O15078 I1836V Neutral Neutral O15078 L906W Neutral Neutral O15078 W7C Disease Disease O15078 R1237H Neutral Neutral O15078 K838E Neutral Neutral Q9HBM0 D762G Neutral Neutral Q07699 C121W Disease Disease Q8N4Y2 Q77R Neutral Neutral Q8N4Y2 I248S Neutral Neutral Q8N4Y2 E153K Neutral Neutral Q8N4Y2 G173S Neutral Neutral P29400 G632D Disease Disease P29400 G866E Disease Disease P29400 G383D Disease Disease P29400 G177C Disease Disease P29400 G902V Disease Disease P29400 G129E Disease Disease P29400 G1107R Disease Disease P29400 G319R Disease Disease P02462 G562E Disease Disease Q01955 G640R Disease Disease P02462 T555P Neutral Disease P29400 G1357S Disease Disease P29400 G1211E Disease Disease P29400 G219S Disease Disease P29400 R1677Q Disease Disease P29400 G420E Disease Disease P29400 G1333S Disease Disease P29400 S1488F Disease Disease P29400 G174R Disease Disease P29400 G400E Disease Disease P29400 G1379V Disease Disease P29400 C1567R Disease Disease Q01955 R408H Neutral Neutral P29400 G1427V Disease Disease P29400 G1442D Disease Disease P29400 G1086D Disease Disease P29400 G638S Disease Disease P29400 G852R Disease Disease P29400 G292V Disease Disease P53420 V1327M Neutral Neutral P29400 P1517T Disease Disease P53420 G1201S Disease Disease P29400 G1244D Disease Disease P29400 M898V Disease Neutral Q01955 G985V Disease Disease P29400 G406V Disease Disease P29400 G681D Disease Disease P53420 G545A Neutral Disease P29400 G624D Disease Disease P29400 G1451S Disease Disease P29400 P739S Disease Neutral P29400 R1511H Disease Neutral Q01955 D1269E Neutral Neutral P29400 G1066S Disease Disease P29400 G1596D Disease Disease P29400 G1143D Disease Disease P29400 G573D Disease Disease P29400 G687E Disease Disease P29400 G295D Disease Disease P29400 G1045E Disease Disease Q01955 G1334E Disease Disease Q01955 L141P Neutral Neutral P29400 G629D Disease Disease P29400 G524D Disease Disease P02462 G749S Disease Disease P29400 G521C Disease Disease P29400 G1015V Disease Disease P29400 A430D Neutral Neutral P53420 G116E Disease Disease P29400 P739A Neutral Neutral P29400 G289V Disease Disease P29400 G374A Disease Disease P29400 G1104V Disease Disease P02462 G1130D Disease Disease P29400 G371E Disease Disease P29400 R1677P Disease Disease P29400 G114S Disease Disease P29400 G1167S Disease Disease P29400 G822R Disease Disease P53420 G999E Disease Disease P53420 P1402S Neutral Neutral P29400 G802R Disease Disease P29400 G521S Disease Disease P29400 R1410C Disease Disease P53420 G960R Disease Disease P29400 E633K Disease Neutral P53420 G897E Disease Disease P29400 G264R Disease Disease P29400 G216R Disease Disease P29400 G638V Disease Disease P29400 G796R Disease Disease P29400 C1678W Disease Disease P53420 P1132L Disease Neutral P29400 G472R Disease Disease Q01955 G853R Disease Disease P29400 G638A Disease Disease Q01955 Q1495R Neutral Neutral P29400 G1205C Disease Disease P29400 G331V Disease Disease P53420 S1403P Neutral Neutral P29400 G869R Disease Disease Q01955 G1216R Disease Disease Q01955 E162G Neutral Neutral P29400 G808E Disease Disease P29400 G953V Disease Disease P29400 G545R Disease Disease P29400 G1261E Disease Disease P29400 G1182R Disease Disease Q01955 R1215Q Disease Neutral P29400 G420V Disease Disease P29400 G567A Disease Disease P53420 I6T Neutral Neutral P29400 G1170S Disease Disease P29400 G603V Disease Disease P29400 A1498D Disease Disease Q01955 D1347E Disease Neutral P29400 G878R Disease Disease P29400 G653R Disease Disease P29400 G852E Disease Disease P29400 C1564S Disease Disease P29400 G1220D Disease Disease P29400 G466E Disease Disease P29400 G1039S Disease Disease P29400 G325E Disease Disease P29400 G1066R Disease Disease P29400 G497C Disease Disease Q01955 G297E Disease Disease P29400 G325R Disease Disease P29400 G722E Disease Disease P29400 G412V Disease Disease P29400 G1229D Disease Disease P02462 Q1334H Neutral Neutral P29400 G743D Disease Disease P29400 G1006V Disease Disease P29400 G1161R Disease Disease Q01955 L1474P Neutral Disease P29400 G811V Disease Disease P29400 G1421W Disease Disease P29400 G177R Disease Disease P29400 L1428M Neutral Neutral P02462 G1236R Disease Disease Q01955 R1661C Disease Disease P29400 G772D Disease Disease P29400 I444S Neutral Neutral P29400 G1211R Disease Disease P29400 W1538S Disease Disease P29400 G558R Disease Disease P02462 V7L Neutral Neutral Q01955 P574L Neutral Neutral P29400 G561R Disease Disease P29400 G409D Disease Disease P29400 G230R Disease Disease P29400 G621C Disease Disease P29400 G204V Disease Disease P29400 R1422C Disease Disease P29400 G129V Disease Disease Q01955 G1015E Disease Disease P29400 G609R Disease Disease P53420 G1030V Disease Disease P29400 P619S Neutral Disease P29400 G545V Disease Disease P29400 G609V Disease Disease Q01955 D326Y Neutral Neutral P29400 G1143S Disease Disease P29400 G1158R Disease Disease P29400 P1559A Neutral Disease P29400 G911E Disease Disease P29400 G239E Disease Disease P29400 K664N Neutral Neutral P53420 A931T Neutral Neutral Q01955 H451R Neutral Neutral P29400 G579E Disease Disease P29400 G1006A Disease Disease P29400 G292R Disease Disease Q01955 G1167R Disease Disease P29400 G941C Disease Disease P29400 G1196R Disease Disease P29400 G740E Disease Disease P29400 G579R Disease Disease P29400 L1649R Disease Disease P29400 G491E Disease Disease Q01955 G407R Disease Disease P29400 G494D Disease Disease Q01955 G43R Neutral Disease P29400 G1241C Disease Disease Q01955 I1330T Disease Neutral P29400 G54D Disease Disease P29400 G635D Disease Disease P29400 G872R Disease Disease P29400 G423E Disease Disease P29400 G192R Disease Disease Q01955 G532D Disease Disease P29400 G947D Disease Disease P29400 G415R Disease Disease Q01955 G739R Disease Disease P29400 G1252S Disease Disease Q01955 G1277S Disease Disease P29400 G1486A Disease Disease P29400 G669A Disease Disease P53420 P482S Neutral Neutral Q01955 G1207E Disease Disease P53420 E570Q Neutral Neutral P53420 P1004L Neutral Neutral P53420 P1572L Disease Disease P29400 G365E Disease Disease P29400 G684V Disease Disease P29400 G1030S Disease Disease P29400 R1563Q Disease Disease P29400 G1270S Disease Disease P29400 G1036V Disease Disease P29400 G1015E Disease Disease P02462 G1423R Disease Disease P29400 G298S Disease Disease Q14749 H177N Disease Disease Q14749 L50P Disease Disease Q14749 N141S Disease Disease P49411 R336Q Disease Disease Q3LXA3 T185A Neutral Neutral Q9UBL6 R397Q Neutral Disease Q9UBL6 P633L Neutral Neutral Q9UBL6 F77L Neutral Disease Q86UY8 A266E Neutral Disease Q9Y617 D100A Disease Disease P32927 G647V Neutral Neutral P32927 V652M Neutral Neutral P32927 E249Q Neutral Neutral P32927 P696S Neutral Neutral P32927 P603T Disease Neutral P51843 L466R Disease Disease P51843 L297P Disease Disease P51843 L278P Disease Disease P51843 L381H Disease Disease P51843 E377K Disease Disease P51843 N440I Disease Disease P51843 I439S Disease Disease P51843 Y380D Disease Disease P51843 V385G Disease Disease P51843 L295P Disease Disease P51843 W291C Disease Disease P51843 R267P Disease Disease P51843 R425T Disease Disease P51843 K382N Disease Disease P51843 A300V Disease Disease P51843 V287G Disease Disease P51843 R425G Disease Disease P51843 A300P Disease Disease P08700 R3C Neutral Neutral P08700 R15H Neutral Neutral P08700 N60S Neutral Neutral P08700 P27S Neutral Neutral Q9HAS3 R585H Neutral Neutral Q9HAS3 P221Q Neutral Disease Q9HAS3 L131F Neutral Neutral Q9HAS3 S5N Neutral Neutral Q9HAS3 Y113C Neutral Disease Q9HAS3 R67K Neutral Neutral Q9HAS3 I328V Neutral Neutral Q9HAS3 D62H Neutral Neutral Q9HAS3 R349Q Neutral Neutral Q9HAS3 R4K Neutral Neutral Q9HAS3 Y513F Neutral Disease Q9HAS3 L418I Neutral Neutral P33897 L654P Disease Disease P33897 S98L Disease Neutral P33897 P484R Disease Disease P33897 S149N Disease Disease P33897 K217E Disease Disease P33897 N13T Neutral Neutral P33897 G608D Disease Disease P33897 H667D Disease Disease P33897 R113P Disease Disease P33897 A626D Disease Disease P33897 R152C Disease Disease P33897 R189W Disease Disease P33897 S342P Disease Disease P33897 S606P Disease Disease P33897 L107P Disease Disease P33897 R401Q Disease Disease P33897 G266R Disease Disease P33897 G116R Disease Disease P33897 R152S Disease Neutral P33897 R113C Disease Neutral P33897 Q556R Disease Disease P33897 P218T Disease Disease P33897 N214D Disease Neutral P33897 R104C Disease Disease P33897 R617G Disease Disease P33897 L322P Disease Disease P33897 W679R Disease Disease P33897 T105P Disease Disease P33897 T105I Disease Disease P33897 V224E Disease Neutral P33897 R554H Disease Disease P33897 L220P Disease Disease P33897 L211P Disease Disease P33897 E90K Disease Disease P33897 Y174D Disease Disease P33897 C88W Disease Disease P33897 Y181C Disease Disease P33897 R617H Disease Disease P33897 R591P Disease Disease P33897 E291K Disease Disease P33897 M566K Disease Neutral P33897 D629H Disease Disease P33897 R163H Disease Disease P33897 R285P Disease Disease P33897 S108L Disease Disease P33897 L190P Disease Disease P33897 T668I Disease Neutral P33897 T693M Disease Neutral P33897 P263L Disease Disease P33897 R274W Disease Disease P33897 C631Y Disease Disease P33897 R591W Disease Disease P33897 S514R Disease Disease P33897 S606L Disease Disease P33897 D221G Disease Disease P33897 K336M Disease Neutral P33897 T254P Disease Disease P33897 E609K Disease Disease P33897 L503P Disease Disease P33897 E630G Disease Disease P33897 R591Q Disease Disease P33897 R518Q Disease Disease P33897 G277R Disease Disease P33897 R418W Disease Disease P33897 R152P Disease Disease P33897 R389G Disease Neutral P33897 A294T Disease Disease P33897 T198K Disease Disease P33897 G512S Disease Disease P33897 G529S Disease Disease P33897 P534L Disease Disease P33897 P143S Disease Neutral P33897 E271K Disease Neutral P33897 R617C Disease Disease P33897 R104H Disease Disease P33897 R182P Disease Disease P33897 S108W Disease Disease P33897 A141T Disease Disease P33897 S161P Disease Disease P33897 S636I Disease Disease P33897 K276E Disease Neutral P33897 E609G Disease Disease P33897 G507V Disease Disease P33897 T632I Disease Disease P33897 R401W Disease Disease P33897 E291D Disease Disease P33897 R163P Disease Disease P33897 F540S Disease Neutral P33897 P560R Disease Disease P33897 S103R Disease Disease P33897 D194H Disease Disease P33897 P543L Disease Disease P33897 V635M Disease Disease P33897 G298D Disease Disease P33897 G343D Disease Disease P33897 G277W Disease Disease P33897 A626T Disease Disease P33897 S213C Disease Neutral P33897 S633R Disease Disease P33897 A616V Disease Disease P33897 R152L Disease Disease P33897 N148S Disease Disease P33897 R660W Disease Disease P33897 D638Y Disease Neutral P33897 P560S Disease Disease P33897 G522W Disease Disease P33897 R518W Disease Disease P33897 A646P Disease Disease P33897 R389H Disease Neutral P33897 S633I Disease Disease P33897 S515F Disease Disease P33897 A99D Disease Disease P33897 T254M Disease Neutral P33897 Y174S Disease Disease P33897 L229P Disease Disease P33897 D200N Disease Disease P33897 Y174C Disease Disease P33897 R280C Disease Disease P33897 Q544R Disease Disease P33897 Q178E Disease Neutral P33897 W339R Disease Disease P33897 D200V Disease Disease P33897 G343S Disease Disease P33897 E302K Disease Disease P33897 P560L Disease Disease P33897 R660P Disease Disease P33897 S552P Disease Disease P33897 Y296C Disease Disease Q5T200 E1429D Neutral Neutral Q9NVV0 C254S Neutral Neutral O95298 L46V Neutral Neutral Q8WV22 S47N Neutral Neutral Q8WV22 T38R Neutral Neutral A8MPX8 A260T Neutral Neutral A8MPX8 F123L Neutral Neutral A8MPX8 R37H Neutral Neutral Q8NHU2 P74R Neutral Disease Q8NHU2 P371L Neutral Neutral Q8NHU2 V369I Neutral Neutral Q8NHU2 D505E Neutral Neutral Q8NHU2 P660L Neutral Neutral Q8NHU2 H254R Neutral Neutral Q8NHU2 V671I Neutral Neutral P28328 E55K Disease Disease Q9GZN7 E59K Neutral Neutral Q03405 L317P Neutral Neutral Q03405 E55G Neutral Neutral Q03405 K220R Neutral Neutral Q03405 T86A Neutral Neutral Q03405 R105Q Neutral Neutral Q03405 N281K Neutral Neutral Q9NZH8 Q69K Neutral Neutral Q8N5Z5 R44G Neutral Disease P18850 A145P Neutral Neutral P18850 P157S Neutral Neutral P18850 M67V Neutral Neutral P18850 M67L Neutral Neutral Q6IPR3 R110Q Neutral Neutral Q6IPR3 M121V Neutral Neutral Q15155 M493V Neutral Neutral Q15155 N490D Neutral Neutral Q15155 I1141F Neutral Neutral Q5JPE7 N726K Neutral Neutral Q5JPE7 V493M Neutral Neutral Q15155 K458N Neutral Neutral Q15155 I404V Neutral Neutral Q5JPE7 V580M Neutral Neutral Q15155 E1081K Neutral Neutral Q15155 R1195G Neutral Neutral Q5JPE7 D490N Neutral Neutral Q9H741 Q55R Neutral Neutral Q9BSA4 P11H Neutral Disease Q9BSA4 D423E Neutral Disease Q9BSA4 H85D Neutral Neutral Q9BSA4 T419I Neutral Neutral Q9BSA4 A265S Neutral Disease Q9BSA4 T262A Neutral Neutral Q14254 A279T Neutral Neutral Q9NVH1 V267M Neutral Neutral Q9NVH1 T290A Neutral Neutral Q7Z2W4 I851T Neutral Neutral Q7Z2W4 R485K Neutral Neutral Q7Z2W4 H565Q Neutral Neutral Q99567 N289S Neutral Neutral Q9ULC3 C85R Disease Disease Q9ULC3 S101A Neutral Neutral Q9ULC3 G207S Neutral Neutral Q9ULC3 K40R Neutral Disease Q96C57 G44R Neutral Neutral O43395 T494M Disease Disease P00439 M276V Disease Disease P00439 S349P Disease Disease P00439 V230I Disease Neutral P00439 R158W Disease Disease P00439 D84Y Disease Disease P00439 K42I Disease Disease P00439 Y325C Disease Disease P00439 L248P Disease Disease P00439 A104D Disease Disease P00439 A47V Disease Neutral P00439 A309V Disease Disease P00439 I65T Disease Disease P00439 D394H Disease Neutral P00439 R261Q Disease Disease P00439 S350T Disease Disease Q8IWU9 R441H Neutral Disease P00439 L212P Disease Disease P00439 P225R Disease Disease P00439 R252G Disease Disease P00439 R297C Disease Disease P00439 C265G Disease Disease P00439 F240S Disease Disease P00439 S110C Disease Neutral P00439 T92I Disease Neutral P00439 G344R Disease Disease P00439 L194P Disease Disease P00439 N207S Disease Neutral P00439 L311P Disease Disease P00439 L430P Disease Disease P00439 G148S Disease Disease P00439 A395G Disease Disease P00439 A403V Disease Neutral P00439 D394A Disease Disease P00439 A246D Disease Disease P00439 M276I Disease Disease P00439 K341R Disease Neutral P00439 S231P Disease Disease P00439 A259T Disease Disease P00439 Y387H Disease Disease P00439 A309D Disease Disease P00439 L333F Disease Disease P00439 G247V Disease Disease P00439 Q304R Disease Disease P00439 P362T Disease Neutral P00439 S310F Disease Disease P00439 C357G Disease Disease P00439 R241L Disease Neutral P00439 P175A Disease Disease P00439 L41F Disease Disease P00439 L242F Disease Neutral P00439 Y154N Disease Disease P00439 A259V Disease Disease P00439 A447D Disease Disease P00439 P211T Disease Neutral P00439 D145V Disease Disease P00439 A345T Disease Disease P00439 D143G Disease Disease P00439 R270K Disease Disease P00439 F331L Disease Disease P00439 N207D Disease Neutral P00439 T278A Disease Disease P00439 G337V Disease Neutral P00439 Q20L Disease Neutral P00439 G344V Disease Disease P00439 R53H Disease Neutral P00439 V388M Disease Disease P00439 R408W Disease Disease P00439 R155P Disease Disease P00439 R158Q Disease Disease P00439 F55L Disease Disease P00439 S231F Disease Disease P00439 K341T Disease Disease P00439 G171A Disease Disease P00439 R413P Disease Disease P00439 V245E Disease Disease P00439 R413S Disease Disease P00439 G218V Disease Disease P00439 E221G Disease Disease P00439 Y277D Disease Disease P00439 N167S Disease Neutral P00439 T124I Disease Neutral P00439 H201Y Disease Disease P00439 I283F Disease Disease P00439 P281L Disease Disease P00439 A300S Disease Disease P00439 R408Q Disease Disease P00439 A322G Disease Disease P00439 D338Y Disease Disease P00439 P225T Disease Disease P00439 D151H Disease Disease P00439 R241C Disease Disease P00439 S16P Disease Neutral P00439 L98S Disease Disease P00439 Y204C Disease Neutral P00439 E205A Disease Disease P00439 T372S Disease Neutral P00439 I318T Disease Neutral P00439 P244L Disease Disease P00439 H170R Disease Disease P00439 I306V Disease Neutral P00439 H271Y Disease Disease P00439 A322T Disease Disease P00439 S40L Disease Disease P00439 A395P Disease Disease P00439 G239S Disease Disease P00439 R169H Disease Disease P00439 F161S Disease Disease P00439 S303P Disease Disease P00439 T278N Disease Neutral P00439 H264L Disease Disease P00439 R252W Disease Disease P00439 R241H Disease Neutral P00439 I164T Disease Neutral P00439 C217G Disease Disease P00439 F263L Disease Disease P00439 D129Y Disease Disease P00439 G257C Disease Disease P00439 E178G Disease Disease P00439 D415N Disease Neutral P00439 S273F Disease Disease P00439 E76A Disease Neutral P00439 A342T Disease Disease P00439 V190A Disease Disease P00439 L348V Disease Disease P00439 S87R Disease Neutral P00439 R252Q Disease Disease P00439 I283N Disease Disease P00439 H146Y Disease Disease P00439 Y343C Disease Disease P00439 T380M Disease Disease P00439 T238P Disease Disease P00439 R270S Disease Disease P00439 I174T Disease Disease P00439 V177L Disease Disease P00439 D282N Disease Disease P00439 D222V Disease Disease P00439 L249F Disease Neutral P00439 A300V Disease Disease P00439 S67P Disease Disease P00439 L213P Disease Disease P00439 N167I Disease Disease P00439 Y414C Disease Disease P00439 H170D Disease Disease P00439 P173T Disease Disease P00439 H201R Disease Neutral P00439 C334S Disease Disease P00439 G46S Disease Neutral P00439 R68S Disease Disease P00439 L255S Disease Neutral P00439 P366H Disease Neutral P00439 S349L Disease Disease P00439 Y206D Disease Disease P00439 R157N Disease Disease P00439 K274E Neutral Neutral P00439 A345S Disease Disease P00439 E330D Disease Disease P00439 I65N Disease Disease P00439 I224M Disease Disease P00439 R176L Disease Disease P00439 L41P Disease Disease P00439 E183Q Disease Disease P00439 E280K Disease Disease P00439 Y277C Disease Disease P00439 L255V Disease Neutral P00439 Y386C Disease Disease P00439 I174V Disease Neutral P00439 R297H Disease Disease P00439 L48S Disease Disease P00439 G171R Disease Disease P00439 P314H Disease Neutral P00439 R176P Disease Disease P00439 V388L Disease Disease P00439 T418P Disease Disease P00439 F39L Disease Disease P00439 V245L Disease Disease P00439 P407S Disease Neutral P00439 R261P Disease Disease P00439 F299C Disease Disease P00439 F233L Disease Disease P00439 I269L Disease Disease P00439 F410S Disease Disease P00439 R243Q Disease Neutral P00439 E390G Disease Disease P00439 L347F Disease Neutral P00439 E56D Disease Neutral P00439 Q160P Disease Disease P00439 Y377C Disease Disease P00439 V245A Disease Disease Q6DD87 G379A Neutral Neutral P51797 G198E Neutral Disease Q8N0Z6 Q14H Neutral Neutral Q8NEV9 S59A Neutral Neutral Q8NEV9 L119P Neutral Neutral Q9BRF8 V86I Neutral Neutral Q9BRF8 A19D Neutral Neutral Q9BRF8 H290P Neutral Disease Q9BRF8 R241K Neutral Neutral P34913 R103C Neutral Neutral P34913 R287Q Neutral Disease Q709F0 R157H Neutral Neutral Q709F0 V362L Neutral Neutral O60784 M264V Neutral Disease Q13043 R310Q Neutral Neutral Q13043 V312M Neutral Neutral Q13043 P416L Neutral Neutral Q13043 I355T Neutral Neutral Q13043 H162N Neutral Neutral Q9BZJ3 V18A Neutral Neutral Q9BZJ3 V76M Neutral Disease Q9BZJ3 P15R Neutral Neutral Q96M86 I934T Neutral Neutral Q96M86 R98H Neutral Neutral Q9UBD9 R197L Disease Neutral Q6P1J9 L384P Neutral Neutral Q6P1J9 L64P Disease Disease Q96KR1 I520T Neutral Neutral Q96KR1 V461I Neutral Neutral P34972 H316Y Neutral Neutral Q96EC8 F202L Neutral Disease Q14232 N208Y Disease Disease Q13474 V65L Neutral Neutral O75610 D322A Neutral Neutral O00292 S92L Neutral Disease O00292 P286L Neutral Disease Q9NSI6 P1699L Neutral Neutral Q9NSI6 S1511P Neutral Neutral Q9NSI6 Q83E Neutral Neutral Q9NSI2 V212L Neutral Neutral Q6IC98 S159I Neutral Neutral Q96IW2 N270S Neutral Neutral Q96IW2 G138S Neutral Neutral Q10469 S290F Disease Disease Q10469 H262R Disease Disease Q10469 N318D Disease Disease P19532 T313A Neutral Neutral P19532 S96C Neutral Neutral P00480 R40H Disease Disease P00480 H202Y Disease Disease P00480 G100D Disease Disease P00480 L244Q Disease Neutral P00480 E181G Disease Disease P00480 I159T Disease Disease P00480 E87K Disease Disease P00480 G197E Disease Disease P00480 S207R Disease Disease P00480 P225T Disease Disease P00480 V339L Disease Disease P00480 G39C Disease Disease P00480 H117L Disease Disease P00480 R40C Disease Disease P00480 P225L Disease Disease P00480 T125M Disease Neutral P00480 Y345D Disease Disease P00480 L111P Neutral Disease P00480 L45P Disease Disease P00480 I172M Disease Neutral P00480 R277Q Disease Disease P00480 G197R Disease Disease P00480 T264I Disease Disease P00480 S203C Disease Disease P00480 L148F Disease Neutral P00480 K46R Neutral Neutral P00480 A209V Disease Disease P00480 A208T Disease Disease P00480 G188R Disease Disease P00480 K88N Disease Disease P00480 H214Y Disease Disease P00480 M213K Disease Disease P00480 D196Y Disease Disease P00480 I172F Disease Neutral P00480 G83D Disease Disease P00480 R277W Disease Disease P00480 A140P Disease Disease P00480 T264A Disease Neutral P00480 R330G Disease Disease P00480 M56T Disease Disease P00480 H302Q Disease Disease P00480 M206R Disease Disease P00480 L63P Disease Disease P00480 L341P Disease Disease P00480 Q270R Neutral Disease P00480 A336S Disease Disease P00480 M268T Disease Disease P00480 G83R Disease Disease P00480 C303R Disease Disease P00480 M206I Disease Disease P00480 S192R Disease Disease P00480 N198K Disease Disease P00480 L45V Disease Neutral P00480 Q216E Disease Neutral P00480 P220A Disease Disease P00480 D126G Disease Disease P00480 N47I Disease Neutral P00480 T247K Disease Neutral P00480 G50R Disease Disease P00480 H255P Disease Neutral P00480 G188V Disease Disease P00480 G269E Disease Disease P00480 T343K Disease Neutral P00480 D263N Disease Disease P00480 Y183D Disease Neutral P00480 I160S Disease Disease P00480 D263G Disease Disease P00480 P225R Disease Disease P00480 Y176C Disease Neutral P00480 T242I Disease Neutral P00480 H117R Disease Disease P00480 R94T Disease Disease P00480 T178M Disease Disease P00480 F354C Disease Neutral P00480 L201P Disease Disease P00480 L43F Neutral Disease P00480 Q180H Disease Neutral P00480 T93A Disease Disease P00480 S60L Disease Disease P00480 H302L Disease Disease P00480 Y345C Disease Disease P00480 D175V Disease Disease P00480 G195R Disease Disease P00480 H182L Disease Disease P00480 S267R Disease Disease P00480 P305H Disease Disease P00480 Y55D Disease Disease P00480 F101L Neutral Disease P00480 R129H Disease Disease P00480 L191F Disease Neutral P00480 C303Y Disease Disease P00480 N161S Disease Disease P00480 A174P Disease Disease P00480 T333A Neutral Neutral P00480 W265L Disease Disease P00480 H168Q Disease Disease P00480 R141Q Disease Disease P00480 R320L Disease Disease P00480 R26Q Disease Neutral P00480 R141P Disease Disease P00480 G79E Disease Disease P00480 E326K Disease Disease P00480 A102E Disease Disease P00480 R92Q Disease Disease P00480 H168R Disease Disease P00480 V337L Disease Neutral P00480 L139S Disease Neutral P00480 T44I Disease Neutral P00480 G162R Disease Disease P00480 L304F Disease Disease P00480 Y183C Disease Neutral P00480 L301F Disease Neutral P00480 H302Y Disease Disease P00480 S90R Disease Disease P00480 T262K Disease Disease P00480 S340P Disease Disease P00480 D196V Disease Disease Q70Z53 H16R Neutral Neutral Q70Z53 R78T Neutral Neutral P05166 G131R Disease Disease P05166 G198D Disease Disease Q9HCC0 S173L Disease Disease P05166 A468T Disease Disease Q9HCC0 E99Q Disease Disease Q9HCC0 R155Q Disease Disease P05166 R410W Disease Disease Q9HCC0 A218T Disease Disease P05166 G112D Disease Disease Q9HCC0 C167R Disease Disease P05166 I430L Disease Disease Q9HCC0 V339M Disease Disease P05166 S106R Disease Disease P05166 A153P Disease Disease Q9HCC0 R268T Disease Neutral P05166 E168K Disease Disease P05166 R44P Disease Disease P05166 M442T Disease Disease Q9HCC0 P310R Disease Disease Q9HCC0 A478G Neutral Disease P05166 T428I Disease Disease P05166 L519P Disease Disease P05166 N536D Disease Disease P05166 R512C Disease Disease P05166 R165Q Disease Disease P05166 L17M Disease Neutral P05166 V107M Disease Disease P05166 Y439C Disease Disease P05166 Y435C Disease Disease P05166 R165W Disease Disease P05166 P228L Disease Disease P05166 G188R Disease Disease Q9HCC0 R193C Disease Disease P05166 A497V Disease Disease P05166 V205D Disease Disease P05166 R67S Disease Disease Q9HCC0 I437V Disease Neutral P05166 G246V Disease Disease Q9H6E5 L442F Neutral Disease Q6ZV73 Q257R Neutral Neutral Q6PL45 I46V Neutral Neutral Q9H300 V262L Neutral Neutral Q9H300 A137G Neutral Neutral Q13492 S383F Neutral Neutral Q13492 T158P Neutral Disease Q13492 W578C Neutral Disease Q13492 F641L Neutral Neutral Q13492 Q579E Neutral Neutral Q16611 A28V Neutral Neutral Q16611 S69R Neutral Neutral Q7Z418 A198G Neutral Neutral Q7Z418 A233V Neutral Neutral Q7Z418 S231P Neutral Neutral Q7Z418 F58Y Neutral Neutral Q7Z418 E255K Neutral Neutral Q7Z418 V346I Neutral Neutral Q5VWC8 T36A Neutral Neutral P51888 N348H Neutral Disease Q13231 A442G Neutral Neutral Q13231 G102S Neutral Disease Q9BZP6 V324G Neutral Neutral O00410 T969I Neutral Neutral O00410 Y905C Neutral Disease O00410 E525K Neutral Neutral O00410 L286I Neutral Neutral O00410 E549K Neutral Disease Q8WW01 G19D Neutral Neutral Q8WW01 Q59H Neutral Disease P43681 E387G Neutral Neutral P43681 S280L Disease Disease P43681 S280F Disease Disease P43681 S517L Neutral Neutral Q14118 W14S Neutral Neutral O14793 K153R Neutral Neutral O14793 A55T Neutral Disease Q9ULK0 V529I Neutral Neutral Q96NU7 G3S Neutral Neutral Q96NU7 P360H Neutral Neutral Q8NCG7 Q664R Neutral Neutral P38570 C1041S Neutral Neutral P38570 R950W Neutral Neutral P38570 Q892H Neutral Neutral P38570 D360E Neutral Neutral Q86TU7 N278D Neutral Disease Q9NRF9 T83A Neutral Neutral Q9NRF9 E135D Neutral Neutral Q96Q83 D228E Neutral Neutral Q96Q83 R164C Neutral Disease Q99469 N262S Neutral Neutral Q9NXI6 A23T Neutral Neutral Q68DV7 I47V Neutral Neutral Q68DV7 P231L Neutral Neutral Q68DV7 R221Q Neutral Neutral Q68DV7 P686R Neutral Neutral Q68DV7 R117H Neutral Neutral Q68DV7 L418M Neutral Neutral Q7Z4H8 R319L Neutral Neutral Q6UW63 I114V Neutral Neutral P53355 G1407V Neutral Neutral P53355 M943T Neutral Neutral P53355 L1010P Neutral Disease P53355 S521A Neutral Disease P53355 K980N Neutral Neutral P53355 N1346S Neutral Neutral P53355 M1274I Neutral Neutral P53355 R979W Neutral Neutral P53355 D1009Y Neutral Neutral P53355 Y995C Neutral Neutral P53355 V416I Neutral Neutral P53355 N1348S Neutral Neutral P53355 T1020A Neutral Neutral P53355 D996E Neutral Neutral P53355 C542Y Neutral Disease P53355 R1012C Neutral Neutral P53355 E1007Q Neutral Neutral P53355 A461S Neutral Neutral Q8TCU5 N835D Neutral Neutral O60391 A845T Neutral Neutral O60391 R404W Neutral Neutral Q8TCU5 R1041Q Neutral Neutral Q8TCU5 R487G Neutral Neutral O60391 T577M Neutral Neutral O60391 T157M Neutral Neutral O60391 W414R Neutral Neutral Q8TCU5 M362V Neutral Neutral O15537 R141C Disease Disease O15537 L13P Disease Disease O15537 G135V Disease Disease O15537 C110Y Disease Neutral O15537 F108C Disease Neutral O15537 L113F Disease Neutral O15537 G140R Disease Disease O15537 C142W Disease Disease O15537 H207Q Disease Disease O15537 G109E Disease Disease O15537 R182C Disease Disease O15537 D158N Neutral Disease O15537 C219G Disease Disease O15537 L216P Disease Disease O15537 G140E Disease Disease O15537 G70S Disease Disease O15537 L103R Disease Disease O15537 P193S Disease Disease O15537 R197C Disease Disease O15537 C219R Disease Disease O15537 R141H Disease Disease O15537 E215K Disease Disease O15537 L127P Disease Disease O15537 E146D Disease Disease O15537 G109W Disease Disease O15537 L12H Disease Neutral O15537 E72D Disease Disease O15537 W163C Disease Disease O15537 Y89C Disease Disease O15537 Y155C Disease Disease O15537 R197H Disease Disease O15537 R102W Disease Disease O15537 I199T Disease Disease O15537 G74V Disease Disease O15537 W96R Disease Disease O15537 C59S Disease Disease O15537 W112C Disease Disease O15537 G178D Disease Disease O15537 R213W Disease Disease O15537 P193L Disease Disease O15537 C223R Disease Disease O15537 R209H Disease Neutral O15537 E146K Disease Disease O15537 I136T Disease Disease O15537 K222N Neutral Neutral O15537 R141G Disease Disease O15537 D143V Disease Neutral O15537 G70A Disease Disease O15537 R102Q Disease Disease O15537 P203L Disease Disease O15537 G109R Disease Disease O15537 E215Q Disease Disease O15537 P192S Disease Disease O15537 R200H Disease Disease O15537 A98E Disease Disease O15537 P192R Disease Disease O15537 R200C Disease Disease O15537 T138A Disease Disease O15537 E72K Disease Disease O15537 Y65C Disease Neutral Q9HA92 A119T Neutral Neutral Q9HA92 L126S Neutral Neutral P13010 L463F Neutral Neutral A6NJG6 R145Q Neutral Neutral Q5MJ09 K43N Neutral Neutral Q8N1G1 S886G Neutral Neutral P02649 P102R Neutral Disease P02649 T60A Neutral Neutral P02649 S314R Neutral Neutral P02649 R269G Neutral Neutral P02649 R176C Disease Neutral P02649 G145D Neutral Neutral P02649 R246C Neutral Neutral P02649 R163C Disease Neutral P02649 K164E Disease Neutral P02649 L270E Neutral Neutral P02649 E31K Disease Neutral P02649 R154C Disease Neutral P02649 R154S Disease Disease P02649 R160C Disease Neutral P02649 R292H Neutral Neutral P02649 R242Q Neutral Neutral P02649 Q64H Neutral Neutral P02649 V254E Neutral Neutral P02649 A117T Neutral Neutral P02649 C130R Disease Neutral P02649 A170P Neutral Neutral P02649 L46P Neutral Disease P02649 A124V Neutral Neutral P02649 K164Q Disease Neutral P02649 E21K Neutral Neutral P02649 R152Q Neutral Neutral P02649 Q99K Neutral Neutral Q9Y250 L475V Neutral Neutral Q9Y250 K119E Disease Neutral Q9Y250 S29P Disease Neutral Q96EK9 D191E Neutral Neutral P50502 M297I Neutral Neutral Q9C0F0 N954S Neutral Neutral Q9C0F0 M1415R Neutral Disease Q9C0F0 M1708V Neutral Neutral Q9C0F0 V1652M Neutral Neutral Q86TY3 V528F Neutral Neutral Q86TY3 A391V Neutral Neutral Q86TY3 T96I Neutral Neutral Q86TY3 Q613E Neutral Neutral P14314 S74N Neutral Neutral P14314 A291T Neutral Neutral Q13426 I134T Neutral Neutral Q13426 A56T Neutral Neutral Q13426 A247S Neutral Neutral Q13426 S12C Neutral Neutral Q13426 Q240P Neutral Neutral Q13426 E142Q Neutral Neutral O76070 E110V Neutral Neutral Q658L1 P34L Neutral Neutral Q658L1 W225R Neutral Disease Q658L1 S8G Neutral Neutral Q969X6 R565W Disease Neutral Q9BRQ6 A95S Neutral Neutral P78314 G420R Disease Neutral P78314 R415P Disease Neutral P78314 P418H Disease Neutral P78314 R415Q Disease Neutral P78314 P418L Disease Neutral P78314 G420E Disease Neutral P78314 P418R Disease Neutral P22304 D252N Disease Neutral P22304 A82V Disease Disease P22304 R88H Disease Disease P22304 H229R Disease Disease P22304 P86R Disease Disease P22304 R88L Disease Disease P22304 L314P Disease Disease P22304 I485R Disease Disease P22304 L259P Disease Disease P22304 P358R Disease Disease P22304 K227Q Disease Neutral P22304 Q121H Disease Neutral P22304 W345C Disease Disease P22304 V89F Disease Neutral P22304 N265I Disease Neutral P22304 Y225D Disease Disease P22304 P86L Disease Disease P22304 P467L Disease Disease P22304 E341K Disease Disease P22304 A79E Disease Disease P22304 L73F Disease Disease P22304 S117Y Disease Disease P22304 R468W Disease Disease P22304 Y523C Disease Disease P22304 P480L Disease Disease P22304 R313C Disease Disease P22304 S349I Disease Neutral P22304 S333L Disease Disease P22304 D334N Disease Disease P22304 E125V Disease Neutral P22304 S71N Disease Disease P22304 P480R Disease Disease P22304 C422G Disease Disease P22304 W502S Disease Disease P22304 L102R Disease Disease P22304 R88C Disease Disease P22304 D269V Disease Disease P22304 P228T Disease Disease P22304 L339R Disease Disease P22304 E434K Disease Disease P22304 S71R Disease Disease P22304 P86Q Disease Disease P22304 K347T Disease Disease P22304 D334G Disease Disease P22304 Y54D Disease Disease P22304 A85S Disease Neutral P22304 H342Y Disease Disease P22304 A82E Disease Disease P22304 W502C Disease Disease P22304 S87N Disease Disease P22304 T309A Disease Neutral P22304 P231L Disease Disease P22304 P120R Disease Disease P22304 Y490S Disease Disease P22304 E521K Disease Disease P22304 D308E Disease Disease P22304 Q465P Disease Disease P22304 P480Q Disease Neutral P22304 R95G Disease Disease P22304 L403R Disease Disease P22304 G336E Disease Disease P22304 H159P Disease Disease P22304 G134R Disease Disease P22304 A68E Disease Disease P22304 W337R Disease Disease P22304 Q293H Disease Neutral P22304 C432Y Disease Disease P22304 L196S Disease Neutral P22304 A85T Disease Neutral P22304 D198G Disease Neutral P22304 G336R Disease Disease P22304 L182P Disease Disease P22304 D148H Disease Neutral P22304 P266R Disease Disease P22304 R88P Disease Disease P22304 P160R Disease Neutral P22304 K227M Disease Neutral P22304 G340D Disease Disease P22304 Y108C Disease Disease P22304 L410P Disease Disease P22304 T118I Disease Disease P22304 H335R Disease Disease P22304 L41P Disease Disease P22304 Y348H Disease Neutral P22304 S132W Disease Neutral P22304 A346V Disease Disease P22304 D45N Disease Disease P22304 C422R Disease Disease P22304 P228L Disease Disease P22304 A205P Disease Disease P22304 K135R Disease Disease P22304 R468G Disease Disease P22304 P469H Disease Disease P22304 R468L Disease Disease P22304 P120H Disease Disease P22304 D308N Disease Disease P22304 S491F Disease Disease P22304 N115Y Disease Disease P22304 G140V Disease Disease P22304 C184W Disease Disease P22304 R468Q Disease Disease P22304 L92P Disease Disease P22304 K347Q Disease Disease P22304 R95T Disease Neutral P22304 S299I Disease Neutral P22304 H229Y Disease Disease P22304 N63D Disease Disease P22304 P266H Disease Neutral P22304 Q121R Disease Disease P22304 D478Y Disease Disease P22304 G224E Disease Disease P22304 C184F Disease Disease P22304 S143F Disease Neutral P22304 K347I Disease Disease P22304 R48P Disease Disease P22304 E521V Disease Disease P22304 Y108S Disease Neutral P22304 N181I Disease Neutral P22304 D478G Disease Neutral P22304 H138D Disease Disease P22304 L221P Disease Disease P22304 R88G Disease Disease P22304 A346D Disease Disease P22304 K135N Disease Disease P22304 G94D Disease Disease P22304 I485K Disease Disease P22304 Y264N Disease Neutral Q8TDQ0 L140R Neutral Disease Q8TEW0 E107D Neutral Neutral Q9BYG3 P144Q Neutral Neutral O43559 P221L Neutral Neutral O60308 L414I Neutral Neutral O60308 A686V Neutral Neutral O60906 R265S Neutral Neutral Q5SZD1 E137Q Neutral Neutral Q5SZD1 P235L Neutral Neutral O00141 A342V Neutral Neutral O00141 V219I Neutral Neutral Q7Z494 L1141P Disease Disease Q7Z494 S1252R Disease Disease Q7Z494 S360T Disease Neutral Q7Z494 N386S Disease Neutral Q7Z494 S1314T Disease Neutral Q7Z494 R397H Disease Neutral Q7Z494 A1221V Disease Neutral Q9BX26 P523L Neutral Neutral O95153 A586T Neutral Neutral O95153 H1118L Neutral Neutral O95153 H1728R Neutral Neutral O95153 W851R Neutral Neutral O95153 Q817R Neutral Neutral O95153 R1253C Neutral Disease O95153 A1140P Neutral Neutral O95153 G1830E Neutral Neutral O95153 Q514R Neutral Neutral O15392 E129K Neutral Neutral Q12840 R280C Disease Disease Q12840 Y276C Disease Disease Q12840 N256S Disease Disease Q12840 A361V Disease Neutral Q9H7T9 K82T Neutral Neutral Q8N9K7 S111T Neutral Neutral Q8N9K7 Q18H Neutral Neutral Q99747 K281N Neutral Neutral Q2TAL6 A120G Neutral Neutral P52945 C18R Disease Disease P52945 R197H Disease Disease P52945 D76N Disease Neutral P52945 Q59L Disease Neutral Q8N0W3 P701L Neutral Neutral Q8N0W3 A858T Neutral Neutral Q8N0W3 R939Q Neutral Neutral Q8N0W3 R939W Neutral Disease Q8N0W3 R571H Neutral Neutral Q8N0W3 V861M Neutral Neutral Q8N0W3 A521T Neutral Neutral Q8N0W3 R901W Neutral Neutral Q8N0W3 V146M Neutral Neutral P58012 S58L Disease Disease P58012 N109K Disease Disease P58012 K193R Disease Neutral P58012 G187D Neutral Neutral P58012 P285S Neutral Neutral P58012 Y258N Disease Neutral P58012 N105S Disease Disease P58012 A179G Neutral Neutral P58012 E69K Disease Neutral P58012 H104R Disease Disease P58012 S217F Disease Neutral P58012 I84S Disease Disease P58012 A66V Disease Disease P58012 L106F Disease Disease P58012 Y215C Disease Neutral Q9UBR1 A85E Disease Neutral Q96BZ4 V135M Neutral Neutral Q96BZ4 E27Q Neutral Neutral P25054 I1259T Disease Neutral P25054 G1312E Disease Neutral P25054 V890I Disease Neutral P25054 Y1027C Disease Disease P25054 R1348W Disease Neutral P25054 I880T Disease Neutral P25054 A1508V Disease Neutral P25054 N942D Disease Neutral P25054 V1326A Disease Neutral P25054 S1495G Disease Neutral P25054 L2839F Disease Neutral P25054 R414C Disease Disease P25054 A1184P Disease Neutral P25054 T1313A Disease Neutral P25054 S2621C Disease Neutral P25054 P1176L Disease Neutral P25054 D1422H Disease Neutral P25054 F1197S Disease Neutral P25054 R1171H Disease Neutral P25054 S1973T Neutral Neutral P25054 E1317Q Neutral Neutral P25054 G1120E Disease Neutral P25054 I1307K Neutral Neutral P25054 I2738T Disease Neutral P25054 G2502S Neutral Neutral P25054 S906Y Disease Neutral P25054 S784T Disease Neutral P25054 N1118D Neutral Neutral P25054 S171I Disease Neutral P25054 V1822D Neutral Neutral P25054 T1292M Neutral Neutral P25054 V1472I Disease Neutral P25054 A1296V Disease Neutral P25054 I1304V Neutral Neutral P25054 R99W Disease Neutral P25054 S722G Disease Neutral P25054 T1496S Neutral Neutral P25054 R1171C Disease Neutral P25054 E911G Disease Neutral P25054 G817C Disease Neutral Q13621 D648N Disease Neutral Q13621 V272F Disease Disease Q96NF6 R95G Neutral Neutral Q96NF6 R26G Neutral Neutral Q96NF6 I81V Neutral Neutral Q9Y231 A237T Neutral Neutral Q9Y231 W358G Neutral Disease P09326 E102Q Neutral Neutral Q6ZMI3 S141N Neutral Neutral Q5W0A0 V653F Neutral Neutral Q5W0A0 S174T Neutral Neutral Q5W0A0 L303P Neutral Neutral Q5W0A0 E178K Neutral Neutral Q5W0A0 R565C Neutral Disease Q5W0A0 P439R Neutral Neutral Q5W0A0 T427I Neutral Neutral Q5W0A0 H453R Neutral Neutral Q5W0A0 E63D Neutral Neutral Q5W0A0 E99G Neutral Neutral P26439 A82T Disease Disease P26439 T259M Disease Neutral P26439 L108W Disease Disease P26439 N100S Disease Disease P26439 E94Q Neutral Neutral P26439 L173R Disease Disease P26439 Y253N Disease Disease P26439 G129R Disease Disease P26439 L236S Disease Neutral P26439 K216E Disease Disease P26439 S213G Disease Neutral P26439 E142K Disease Disease P26439 G15D Disease Disease P14060 I79V Neutral Neutral P26439 P222Q Disease Disease P26439 A167V Disease Neutral P26439 P222T Disease Neutral P26439 P222H Disease Neutral P26439 L205P Disease Disease P26439 P155L Disease Neutral P26439 T259R Disease Disease P26439 P186L Disease Disease P26439 G294V Disease Disease Q9H2F3 T250A Neutral Neutral P14060 F286L Neutral Neutral P26439 A10V Disease Disease P26439 A10E Disease Disease P26439 A245P Disease Disease P14060 T367N Neutral Neutral P26439 Y254D Disease Disease P61803 A83T Neutral Neutral Q99720 Q2P Neutral Neutral Q99720 R211Q Neutral Neutral Q68D91 A128T Neutral Neutral Q8NBQ7 G102S Neutral Neutral Q13873 G182D Disease Disease Q13873 R491Q Disease Disease Q13873 C60Y Disease Disease Q13873 D485G Disease Disease Q13873 C118W Disease Disease Q13873 C483R Disease Disease Q13873 C117Y Disease Disease Q13873 S775N Neutral Neutral Q13873 K512T Disease Neutral Q13873 C347Y Disease Disease Q13873 C123S Disease Disease Q13873 Q82H Disease Disease Q13873 R491W Disease Disease Q13873 C123R Disease Disease Q13873 C420R Disease Disease Q13873 R899P Disease Neutral Q13873 N519K Disease Neutral Q13873 E224D Neutral Neutral Q8IWA5 R154Q Neutral Neutral Q9UBT7 I593N Neutral Disease Q9UBT7 M716R Neutral Neutral Q9UBT7 E527Q Neutral Neutral Q9UBT7 N91T Neutral Neutral Q9UBT7 E203K Neutral Neutral Q9UBT7 T424S Neutral Neutral Q4VNC1 I181M Neutral Neutral Q4VNC1 E646D Neutral Neutral Q4VNC1 V353A Neutral Disease Q6ZU11 S390L Neutral Neutral Q6ZU11 S518C Neutral Neutral Q6ZU11 I232T Neutral Neutral Q9BU70 V252A Neutral Neutral Q9BU70 S7P Neutral Neutral Q9BU70 V324M Neutral Neutral Q8TDW7 N2293S Neutral Neutral Q8TDW7 I2755V Neutral Neutral Q8TDW7 S412F Neutral Neutral Q8TDW7 V3518L Neutral Neutral Q8TDW7 V1167G Neutral Neutral Q8TDW7 V2622F Neutral Disease Q8TDW7 Q1726R Neutral Neutral Q8TDW7 S3812G Neutral Neutral Q8TDW7 I462V Neutral Neutral Q9Y4B5 D889G Neutral Neutral Q9Y4B5 R852Q Neutral Neutral Q9Y4B5 G1088S Neutral Neutral Q9Y4B5 K1202Q Neutral Neutral O43189 K304R Neutral Neutral Q8NE00 V58M Neutral Neutral Q8NE00 A439T Neutral Disease Q2HXU8 T6N Neutral Disease Q2HXU8 V116L Neutral Neutral Q5QGZ9 Q254K Neutral Neutral Q8TBX8 K241R Neutral Disease Q8TBX8 G300A Neutral Neutral P48426 N251S Neutral Neutral Q8TBX8 V84A Neutral Neutral Q96Q42 E159K Neutral Neutral Q96Q42 I94V Neutral Neutral Q96Q42 S1255F Neutral Disease Q96Q42 R1406K Neutral Neutral Q96Q42 H102R Neutral Disease Q96Q42 M368V Neutral Neutral Q9BZA8 V917F Neutral Neutral Q9BZA8 N1012K Neutral Neutral P41238 M80I Neutral Neutral Q0VDD7 Q500R Neutral Neutral Q0VDD7 G267R Neutral Neutral Q7L8W6 G41E Neutral Neutral Q7L8W6 R236P Neutral Neutral Q9HCS7 A702T Neutral Neutral Q9HCS7 V126I Neutral Neutral Q9HCS7 R454Q Neutral Neutral Q16531 L427F Neutral Neutral O00716 D389N Neutral Neutral O00716 G344R Neutral Disease P02768 E121G Neutral Disease P02768 L90P Disease Disease P02771 K187Q Neutral Neutral P02768 F73Y Neutral Neutral P02771 A570G Neutral Neutral P02768 R242P Disease Disease P02768 E420K Neutral Neutral P02768 A215T Neutral Neutral P02768 A215V Neutral Neutral P02768 Q220L Neutral Neutral P02768 K490E Neutral Neutral P02768 R242H Disease Neutral P60153 S204P Neutral Neutral P01233 S147C Neutral Neutral P01233 D137A Neutral Neutral P01233 R28W Neutral Neutral P01233 N97D Neutral Neutral P01233 R30H Neutral Neutral P01233 T18A Neutral Neutral P01233 K22R Neutral Neutral P01233 T35I Neutral Disease P01233 F4L Neutral Neutral Q8WUF8 S131N Neutral Neutral Q9NZM5 S16R Neutral Neutral Q9NZM5 Q389R Neutral Neutral Q86VD9 I456M Neutral Neutral Q86VD9 V386A Neutral Neutral Q86VD9 Q309R Neutral Neutral Q8IVD9 R235C Neutral Neutral P46013 V1559M Neutral Neutral P46013 S2793N Neutral Neutral P46013 I631L Neutral Neutral P46013 L1470W Neutral Neutral P46013 R2649H Neutral Neutral P46013 T1849A Neutral Neutral P46013 G1042S Neutral Neutral P46013 L1951I Neutral Neutral P46013 R832W Neutral Disease P46013 Q2904R Neutral Neutral P46013 T3150S Neutral Neutral P46013 N2363S Neutral Neutral P46013 Q574P Neutral Neutral P46013 E1403V Neutral Neutral P46013 L854V Neutral Neutral P46013 P2608L Neutral Neutral P46013 W238R Neutral Neutral P46013 D2760G Neutral Neutral P46013 P1622L Neutral Neutral P46013 K3217E Neutral Neutral P46013 T1247I Neutral Neutral P46013 R2845H Neutral Neutral P46013 T1120S Neutral Neutral P46013 T2868S Neutral Neutral P46013 T2720P Neutral Neutral P46013 N3097D Neutral Neutral P46013 E497D Neutral Neutral P46013 A872V Neutral Neutral P46013 T2337N Neutral Neutral P46013 N104S Neutral Neutral P46013 E3102G Neutral Neutral P46013 R1876Q Neutral Neutral P46013 I2101T Neutral Neutral P46013 R2786Q Neutral Neutral P37088 S562L Disease Disease P37088 W493R Neutral Disease P37088 G327C Disease Disease P37088 C618F Neutral Neutral P37088 T663A Neutral Neutral Q15517 S410L Neutral Neutral Q15517 D527N Neutral Neutral Q15517 S150N Neutral Neutral Q15517 S408A Neutral Neutral Q15517 M18L Neutral Neutral Q15517 S143N Neutral Neutral Q15517 S401G Neutral Neutral Q15517 L56F Neutral Neutral Q15517 S202F Neutral Neutral P01210 G247D Neutral Neutral Q6PHW0 L260P Neutral Disease Q9Y6E2 D44A Neutral Disease Q13219 S1225Y Neutral Neutral Q13219 R945S Neutral Neutral P16442 P74S Neutral Disease P16442 V277M Neutral Neutral P16442 R161H Neutral Neutral P16442 M288R Neutral Disease P16442 G235S Neutral Disease P16442 E223D Neutral Disease P16442 R63H Neutral Neutral P16442 R352G Neutral Disease P16442 K346M Neutral Disease P16442 F216I Neutral Disease P16442 M214R Neutral Disease P16442 R176G Neutral Neutral P16442 G268R Neutral Disease P16442 P257L Neutral Disease P16442 R199C Neutral Disease P16442 G35R Neutral Disease P16442 G268A Neutral Neutral P16442 D291N Neutral Disease P16442 V36F Neutral Neutral P16442 L266M Neutral Neutral P16442 P156L Neutral Disease P16442 R352W Neutral Disease P16442 R198W Neutral Neutral P16442 T163M Neutral Neutral O00303 P39L Neutral Neutral O00303 W172L Neutral Disease O00305 C104F Disease Disease P54284 R423H Neutral Neutral O60832 L72Y Disease Disease O60832 M350I Disease Disease O60832 T66A Disease Disease O60832 S121G Disease Neutral O60832 A2V Disease Neutral O60832 G402R Disease Disease O60832 F36V Disease Disease O60832 I38T Disease Disease O60832 M350T Disease Disease O60832 T49M Disease Neutral O60832 P40R Disease Disease O60832 G223D Neutral Disease O60832 A353V Disease Neutral O60832 K39E Disease Disease O60832 L321V Disease Disease O60832 G402E Disease Disease O60832 E41K Disease Neutral O60832 R65T Disease Disease Q9BXL6 R547S Neutral Neutral Q9BXL6 R883H Neutral Neutral Q8N307 S671C Neutral Neutral Q8N307 C3S Neutral Neutral Q8N307 R666W Neutral Disease Q8N307 P590L Neutral Neutral Q8N307 V18G Neutral Neutral Q8N307 I442T Neutral Neutral P33992 V258I Neutral Neutral P33992 S136T Neutral Neutral P33992 T180S Neutral Neutral Q96JJ7 P61S Neutral Disease O94955 R20Q Neutral Neutral O94955 P21R Neutral Neutral O94955 N262D Neutral Neutral Q9NUR3 L33M Neutral Neutral Q8TBB5 L155V Neutral Neutral Q8TBB5 L56V Neutral Neutral P80404 Q56R Neutral Neutral P80404 R220K Disease Disease Q9BYK8 E2049Q Neutral Neutral Q9BYK8 R1123H Neutral Neutral Q9BYK8 N788S Neutral Neutral Q9BYK8 L2016P Neutral Neutral P07686 R505Q Disease Disease P07686 K121R Neutral Neutral P07686 A543T Disease Disease P07686 I207V Neutral Neutral P07686 C309Y Disease Neutral P07686 S255R Disease Disease P07686 P417L Disease Disease P07686 Y456S Disease Disease P07686 C534Y Disease Neutral P07686 P504S Disease Disease P07686 S62L Disease Neutral Q2EN02 C130F Neutral Disease Q7Z5V6 S382T Neutral Neutral Q7Z5V6 T238N Neutral Neutral Q5VZP5 K855Q Neutral Neutral Q5VZP5 T1124N Neutral Neutral Q5VZP5 A505T Neutral Neutral Q5VZP5 R466H Neutral Neutral Q5VZP5 E265D Neutral Neutral Q8WUB2 R225G Neutral Disease Q9ULD9 N721T Neutral Neutral Q96C23 N190Y Neutral Neutral Q9ULD2 Q1201R Disease Disease Q9ULD2 A563S Disease Neutral Q9ULD2 K453T Neutral Neutral Q9ULD2 T425M Neutral Neutral Q9ULD2 Q75K Disease Neutral Q9ULD2 C148R Neutral Disease Q9ULD2 E1105Q Neutral Neutral Q9ULD2 N873H Disease Neutral Q9ULD2 K1063T Neutral Neutral Q9ULD2 K911T Neutral Neutral Q9ULD2 H575R Neutral Neutral P18848 Q22P Neutral Neutral P18848 E322D Neutral Neutral P18848 P258A Neutral Neutral Q6NSX1 I206V Neutral Neutral P04090 M28K Neutral Neutral P04090 P68Q Neutral Neutral P04808 K28M Neutral Neutral Q14457 I403T Neutral Disease Q14457 A103V Neutral Neutral O95544 N262K Neutral Neutral Q8IYS4 A241V Neutral Neutral Q8IYS4 C302R Neutral Neutral Q8IYS4 E88D Neutral Neutral Q8IYS4 P143S Neutral Neutral Q8IYS4 R354Q Neutral Neutral Q8IYS4 E232K Neutral Neutral Q8IYS4 S190L Neutral Neutral Q8IXI1 R425C Neutral Disease Q8IXI1 R245Q Neutral Neutral Q96KQ7 Y1165F Neutral Neutral Q96KQ7 T55N Neutral Neutral Q96NR2 V121I Neutral Neutral Q8WWZ1 A51D Neutral Neutral Q8WWZ1 I44T Neutral Neutral Q8TE02 D303Y Neutral Neutral P21757 F23C Neutral Neutral P21757 P275A Neutral Neutral Q14209 Q226H Neutral Neutral Q14209 G205R Neutral Neutral Q8N6T7 S46N Neutral Neutral Q9BYW2 P1962L Neutral Neutral Q9BYW2 A1868D Neutral Neutral Q9BYW2 V768L Neutral Neutral P51787 P448R Disease Neutral P51787 S225L Disease Neutral P51787 V254M Disease Neutral P51787 G345E Disease Disease P51787 R555C Disease Disease P51787 R174H Disease Disease P51787 W305S Disease Disease P51787 R366Q Disease Disease P51787 S140G Disease Neutral P51787 A341V Disease Disease P51787 A344V Disease Disease P51787 R366P Disease Disease P51787 E160K Disease Disease P51787 I313M Disease Neutral P51787 R533W Disease Neutral P51787 T391I Disease Disease P51787 R366W Disease Disease P51787 L273F Disease Disease P51787 G306R Disease Disease P51787 E261D Disease Disease P51787 Y111C Disease Disease P51787 Y184S Disease Disease P51787 A525T Disease Disease P51787 D242N Disease Neutral P51787 G168R Disease Disease P51787 E261K Disease Disease P51787 G189R Disease Disease P51787 T309R Disease Disease P51787 V417M Disease Neutral P51787 Y315S Disease Disease P51787 R243C Disease Disease P51787 W392R Disease Disease P51787 R190Q Disease Disease P51787 Y315C Disease Disease P51787 A300T Disease Disease P51787 Y281C Disease Disease P51787 G314S Disease Disease P51787 G179S Disease Disease P51787 G216R Disease Neutral P51787 G269D Disease Disease P51787 S373P Disease Disease P51787 T311I Disease Disease P51787 V307L Disease Neutral P51787 R594Q Disease Neutral P51787 R583C Disease Disease P51787 A178T Disease Disease P51787 K318N Disease Neutral P51787 D317N Disease Disease P51787 G345R Disease Disease P51787 G269S Disease Disease P51787 A341E Disease Disease P51787 W248R Disease Disease P51787 P320A Disease Neutral P51787 A194P Disease Disease P51787 G589D Disease Neutral P51787 T587M Disease Neutral P51787 S349W Disease Disease P51787 L342F Disease Disease P51787 V310I Disease Neutral P51787 A371T Disease Disease P51787 T312I Disease Disease P51787 L266P Disease Disease P51787 A178P Disease Disease P51787 S566F Disease Disease P51787 R243H Disease Disease P51787 L353P Disease Disease P51787 G325R Disease Disease P51787 G643S Neutral Neutral P51787 F157C Disease Disease P51787 R591H Disease Disease P51787 R539W Disease Neutral P51787 L250H Disease Neutral P51787 R174C Disease Disease P29374 N724S Neutral Neutral P29374 H412P Neutral Neutral P29374 A779T Neutral Neutral P03905 M294T Neutral Disease P03905 V313I Disease Neutral P03905 A79P Neutral Disease P03905 R340H Disease Disease P03905 T109P Neutral Disease P03905 I132T Neutral Disease P03905 T109A Disease Neutral Q9H5Z1 P703L Neutral Neutral P49711 K344E Disease Disease P49711 R448Q Disease Neutral P49711 H345R Disease Disease P49711 R339W Disease Disease Q9HBV2 L237S Neutral Neutral Q92913 K197Q Neutral Neutral Q92915 G42C Neutral Neutral Q92915 F145S Disease Disease Q92914 R163G Neutral Disease Q8IY92 P439L Neutral Neutral Q8IY92 S588F Neutral Neutral Q8IY92 A538V Neutral Neutral Q6NUQ1 P759L Neutral Neutral Q6NUQ1 F668S Neutral Neutral P21127 R57C Neutral Neutral Q9UQ88 R93W Neutral Neutral P21127 S414L Neutral Neutral P21127 L601Q Neutral Disease P21127 R201W Neutral Neutral P21127 I463V Neutral Neutral Q9UQ88 L399S Neutral Neutral P21127 K641N Neutral Neutral P21127 A670V Neutral Disease P58753 A9P Neutral Neutral P58753 S55N Neutral Neutral P58753 D96N Neutral Neutral P58753 R13W Neutral Neutral P58753 S180L Neutral Neutral P49902 T3A Neutral Neutral P49902 Q136R Neutral Neutral Q07812 G67R Disease Neutral Q07812 G108V Disease Disease Q16819 V469L Neutral Neutral Q16819 R476G Neutral Disease Q16819 M634V Neutral Neutral Q16819 T726M Neutral Neutral P12314 L105P Neutral Disease O75593 S113T Disease Neutral O75593 T125S Disease Neutral Q9UHW9 F415S Neutral Neutral Q9Y666 A408T Neutral Neutral Q7Z403 W125R Neutral Neutral Q9Y6Q2 Q607H Neutral Neutral Q9Y6Q2 R127T Neutral Neutral Q9Y6Q2 Q544H Neutral Neutral Q96IV0 V581I Neutral Neutral Q96IV0 Q591R Neutral Neutral P14222 I224N Disease Disease P14222 G429E Disease Disease P14222 V50M Disease Neutral P14222 V183G Disease Neutral P14222 R225W Disease Disease P14222 P345L Disease Disease P14222 C279Y Disease Disease P14222 R123H Neutral Neutral P14222 V135M Neutral Neutral P14222 N252S Disease Neutral O75923 R555W Disease Disease O75923 R1038Q Disease Neutral Q9NZM1 Y1198F Neutral Neutral O75923 R2042C Disease Disease Q9NZM1 R1783Q Neutral Disease O75923 R959W Disease Disease O75923 E1335K Disease Disease Q9NZM1 R1399C Neutral Disease O75923 R1046H Disease Neutral O75923 I1298V Disease Neutral O75923 P791R Disease Disease O75923 H1857R Disease Disease O75923 R1693Q Disease Disease O75923 I1208M Disease Neutral O75923 C456W Disease Disease O75923 R2000Q Disease Neutral O75923 G299E Disease Disease P08397 D99N Disease Disease P08397 G335D Disease Disease P08397 K98R Disease Disease P08397 A31T Disease Disease P08397 L92P Disease Disease P08397 A270D Disease Neutral P08397 D61N Disease Disease P08397 R22C Disease Disease P08397 Q34P Disease Disease P08397 A219D Disease Disease P08397 D61Y Disease Disease P08397 E250Q Disease Disease P08397 S28N Disease Disease P08397 G111R Disease Disease P08397 R167W Disease Disease P08397 A270G Disease Neutral P08397 R167Q Disease Disease P08397 L244P Disease Neutral P08397 G274R Disease Disease P08397 H256N Disease Neutral P08397 T78P Disease Disease P08397 D178N Disease Disease P08397 R26C Disease Disease P08397 C261Y Disease Disease P08397 L42S Disease Disease P08397 V90G Disease Neutral P08397 G216D Disease Disease P08397 Q217L Disease Disease P08397 L177R Disease Disease P08397 P119L Disease Disease P08397 L254P Disease Disease P08397 A252V Disease Disease P08397 A122G Disease Disease P08397 E223K Disease Disease P08397 G236S Disease Neutral P08397 V222M Disease Neutral P08397 R195C Disease Disease P08397 A55S Disease Neutral P08397 R173W Disease Disease P08397 G24S Disease Disease P08397 A31P Disease Disease P08397 M18I Disease Disease P08397 V124D Disease Disease P08397 E209K Disease Disease P08397 V202L Disease Neutral P08397 R225Q Disease Disease P08397 G280R Disease Disease P08397 S96F Disease Disease P08397 M212V Disease Neutral P08397 L85R Disease Disease P08397 C247R Disease Disease P08397 E86V Disease Neutral P08397 L343P Disease Disease P08397 E250K Disease Disease P08397 D99G Disease Disease P08397 V267M Disease Neutral P08397 L245R Disease Disease P08397 I113T Disease Disease P08397 R149Q Disease Disease P08397 L238R Disease Disease P08397 V93F Disease Disease P08397 E250V Disease Disease P08397 R173Q Disease Disease P08397 Q34R Disease Disease P08397 H256Y Disease Neutral P08397 T35M Disease Neutral P08397 R116Q Disease Disease P08397 G260D Disease Disease P08397 R201W Disease Disease P08397 E80G Disease Disease P08397 A252T Disease Disease P08397 L278P Disease Disease P08397 L81P Disease Disease P08397 R116W Disease Disease P08397 T269I Disease Neutral P08397 E250A Disease Disease P08397 C247F Disease Disease P08397 R225G Disease Disease P08397 R149L Disease Disease P08397 D99H Disease Disease P08397 R26H Disease Disease P08397 Q217H Disease Disease P08397 Q34K Disease Disease P08397 G335S Disease Disease Q9NYA4 V170L Neutral Neutral Q9NYA4 S280G Neutral Neutral Q9NYA4 V297G Neutral Neutral Q52M75 R85C Neutral Neutral Q8N2F6 P190S Neutral Neutral P28072 P107A Neutral Disease Q2WGJ9 D1110E Neutral Neutral Q86UP8 H514N Neutral Neutral Q92620 T1217A Neutral Neutral Q9H4A9 H468D Neutral Neutral P34931 T479M Neutral Disease P08107 N499S Neutral Disease P34931 T493M Neutral Disease P54652 C191S Neutral Neutral P08107 E110D Neutral Neutral P08107 I95V Neutral Neutral P54652 K496E Neutral Disease P34931 D294G Neutral Disease P34931 E602K Neutral Disease P17066 D562E Neutral Neutral P34931 A268T Neutral Neutral P17066 L198F Neutral Disease P34931 E558A Neutral Neutral P34931 A8P Neutral Disease P08107 A467V Neutral Disease P11021 N543H Neutral Neutral Q6UYE1 A83V Neutral Neutral Q86VW0 Y49F Neutral Disease O14788 M199K Disease Disease Q9NVC3 T78I Neutral Neutral Q9NVC3 L46P Neutral Neutral Q9UGM1 S442N Neutral Neutral Q9UGM1 R96Q Neutral Neutral Q92600 I143T Neutral Disease Q05066 V60A Disease Disease Q05066 P131R Disease Disease Q05066 F67V Disease Disease Q05066 R76S Disease Disease Q05066 G95E Disease Disease Q05066 A113T Disease Disease Q05066 F109S Disease Disease Q05066 P125L Disease Disease Q05066 S3L Disease Neutral Q05066 R133W Disease Disease Q05066 M64R Disease Disease Q05066 I68T Disease Disease Q05066 Y127F Disease Disease Q05066 L101H Disease Disease Q05066 I90M Disease Disease Q05066 Y127C Disease Disease Q05066 R62G Disease Disease Q05066 P108R Disease Disease Q05066 S91G Disease Disease Q05066 S18N Disease Neutral Q05066 M78T Disease Disease Q05066 K106I Disease Disease Q05066 G95R Disease Disease Q05066 M64I Disease Disease Q05066 V60L Disease Disease Q05066 N87Y Disease Disease Q8TD10 Q141L Neutral Neutral Q7Z442 R252W Neutral Neutral Q7Z442 V169M Neutral Neutral Q7Z442 N407S Neutral Neutral Q7Z442 V156I Neutral Neutral Q7Z442 L919M Neutral Neutral Q7Z442 G205R Neutral Neutral Q7Z442 Q120L Neutral Neutral Q7Z442 M1042V Neutral Neutral Q7Z442 V863A Neutral Neutral Q7Z442 L1036P Neutral Disease Q7Z442 N77K Neutral Neutral Q7Z442 R636H Neutral Neutral Q7Z442 R849H Neutral Neutral Q7Z442 W73R Neutral Neutral Q7Z442 L462V Neutral Neutral Q7Z442 V20A Neutral Neutral Q7Z442 P711L Neutral Neutral Q7Z442 K416Q Neutral Neutral Q7Z442 G785C Neutral Neutral Q7Z442 G129D Neutral Neutral Q7Z442 E221G Neutral Neutral Q7Z442 A301P Neutral Neutral Q7Z442 L173S Neutral Neutral Q7Z442 P512L Neutral Disease Q7Z442 C162S Neutral Disease Q7Z442 I183V Neutral Neutral Q99665 A625V Neutral Neutral Q99665 G420R Neutral Neutral Q99665 R149Q Neutral Disease Q99665 I185V Neutral Neutral Q99665 L808R Neutral Disease Q99665 H720R Neutral Neutral Q99665 M13V Neutral Neutral Q99665 R313G Neutral Neutral Q99665 G465D Neutral Neutral Q99665 Q426H Neutral Neutral Q99665 T201I Neutral Neutral P23560 V66M Neutral Neutral P01138 V72M Neutral Neutral P23560 T2I Disease Neutral P01138 R80Q Neutral Disease P23560 R125M Neutral Neutral P23560 Q75H Neutral Neutral P23560 R127L Neutral Disease P01138 A35V Neutral Neutral P01138 R221W Disease Disease Q8IXS0 V431I Neutral Neutral Q96P69 A330T Neutral Neutral Q96P69 R342H Neutral Neutral Q96P69 R201S Neutral Neutral Q9Y6H5 R621C Disease Neutral Q8TAQ9 I127V Neutral Neutral Q8TAQ9 L177V Neutral Neutral O75844 T137A Neutral Neutral O75844 W340R Disease Disease Q6PKH6 L17M Neutral Neutral O00339 E356K Neutral Disease P16860 M93L Neutral Neutral P16860 R47H Neutral Neutral P16860 R25L Neutral Neutral Q8TEV9 N636S Neutral Neutral Q8TEV9 R556H Neutral Neutral Q8TEV9 P524L Neutral Neutral Q9UGT4 S110T Neutral Neutral Q9UGT4 R59Q Neutral Neutral Q9UGT4 N466S Neutral Disease Q8IU68 N306I Neutral Disease P49848 C36S Neutral Neutral Q9H173 Q80R Neutral Neutral P17813 C53R Disease Disease P17813 C412S Disease Disease P17813 W149C Disease Disease P17813 G52V Disease Neutral P17813 L8P Disease Disease P17813 L306P Disease Disease P17813 L221P Disease Disease P17813 D366H Neutral Neutral P17813 V504M Disease Neutral P17813 V49F Disease Disease P17813 L107R Disease Disease P17813 T5M Neutral Neutral P17813 G413V Disease Disease P17813 S615L Disease Disease P17813 I263T Disease Disease P17813 A160D Disease Neutral Q9NRC9 L31P Neutral Disease Q8WXX0 P1971L Neutral Disease Q8WXX0 D565H Neutral Neutral Q8WXX0 K825E Neutral Neutral Q8WXX0 T2569I Neutral Neutral Q8WXX0 M2020T Neutral Neutral Q8WXX0 P3319L Neutral Disease Q8WXX0 H169P Neutral Disease Q8WXX0 A280T Neutral Neutral Q8WXX0 K675E Neutral Neutral Q8WXX0 I2809V Neutral Neutral Q8WXX0 R545C Neutral Disease Q8WXX0 E1525K Neutral Disease Q8WXX0 R3386H Neutral Disease Q8WXX0 R1886Q Neutral Neutral Q8WXX0 P1422T Neutral Neutral Q8WXX0 I315V Neutral Neutral Q8WXX0 N2459K Neutral Neutral Q8WXX0 S438N Neutral Neutral Q8WXX0 P1940L Neutral Neutral Q8N6L1 G32V Neutral Disease Q8WTQ4 R152Q Neutral Neutral Q8NDX1 G269A Neutral Neutral P38117 D128N Disease Disease P38117 T154M Neutral Neutral P38117 R164Q Disease Disease Q8NEC5 G133S Neutral Neutral Q8NEC5 I652V Neutral Neutral Q8NEC5 T730P Neutral Neutral P55017 M672I Disease Disease P55017 S555L Disease Disease P55017 V677L Disease Disease P55017 R209W Disease Disease P55017 S178L Disease Disease P55017 W172R Disease Disease P55017 D486N Disease Disease P55017 A226T Disease Disease P55017 T180K Disease Disease P55017 R158Q Disease Disease P55017 R642G Disease Disease P55017 V153M Disease Disease P55017 T60M Disease Disease P55017 G374V Disease Disease P55017 L850P Disease Disease P55017 S615L Disease Disease P55017 E68K Disease Disease P55017 L849H Disease Disease P55017 R321W Disease Neutral P55017 G729V Disease Disease P55017 R904Q Neutral Neutral P55017 G630V Disease Disease P55017 S283Y Disease Disease P55017 R145H Disease Disease P55017 G867S Disease Neutral P55017 T649R Disease Disease P55017 R642C Disease Disease P55017 R655C Disease Disease P55017 A588V Disease Disease P55017 A313V Disease Neutral P55017 A728T Neutral Neutral P55017 R655L Disease Disease P55017 G496C Disease Disease P55017 G186D Disease Neutral P55017 R955Q Disease Disease P55017 P643L Disease Disease P55017 R334W Disease Disease P55017 C985Y Disease Disease P55017 V578M Disease Neutral P55017 K284R Disease Disease P55017 T304P Disease Disease P55017 H90Y Disease Disease P55017 R852H Disease Neutral P55017 L215P Disease Disease P55017 P349L Disease Disease P55017 A569E Disease Disease P55017 L623P Disease Disease P55017 R655H Disease Disease P55017 R919C Neutral Disease P55017 R852C Disease Disease P55017 R642H Disease Disease P55017 G463E Disease Disease P55017 L738R Disease Disease P55017 G731R Disease Disease P55017 R871H Disease Neutral P55017 A464T Disease Disease P55017 C421R Disease Disease P55017 G741R Disease Disease P55017 G316V Disease Disease P55017 I154F Disease Disease P55017 D62N Disease Disease P55017 S615W Disease Disease P55017 R399C Disease Disease P55017 H69N Disease Neutral P55017 L542P Disease Disease P55017 G342A Disease Neutral P55017 K478E Disease Disease P55017 G439S Disease Disease P55017 P560H Disease Disease P55017 T163M Disease Disease P55017 G613S Disease Disease P55017 R209Q Disease Disease P55017 V677M Disease Disease P55017 R261H Disease Disease P55017 G264A Neutral Disease P55017 G230D Disease Disease P55017 A569V Disease Neutral P55017 R852S Disease Neutral P55017 R958G Disease Disease A0AV02 R181C Neutral Disease A0AV02 P266L Neutral Neutral A0AV02 R664Q Neutral Neutral A0AV02 K541R Neutral Neutral O00762 G25D Neutral Disease P22105 H1248R Neutral Neutral P22105 G2555S Neutral Neutral P22105 R511H Neutral Disease P22105 E2578G Neutral Neutral P22105 P2363H Neutral Neutral Q9Y3R4 S11R Neutral Neutral Q9Y3R4 R41Q Neutral Disease P23497 E699G Neutral Disease P23497 M433V Neutral Neutral P30084 V11A Neutral Neutral Q86YB7 N119D Neutral Neutral P30084 T75I Neutral Neutral Q9NP86 V128A Neutral Neutral Q9NP86 T65R Neutral Disease Q96ES6 G292R Neutral Disease Q16589 E28G Neutral Disease Q16589 L4V Neutral Neutral P50553 E158G Neutral Disease Q9BYD6 T25K Neutral Neutral Q9BYD6 F155S Neutral Neutral O75800 R407Q Disease Neutral Q5VVW2 A752S Neutral Neutral Q5VVW2 H108R Neutral Disease P54803 G95D Disease Neutral P54803 G270D Disease Disease P54803 T96A Disease Neutral P54803 T262I Disease Neutral P54803 I289V Neutral Neutral P54803 R515C Disease Disease P54803 P384L Disease Neutral P54803 S287F Disease Neutral P54803 G95S Disease Disease P54803 F498S Disease Disease P54803 P302A Disease Disease P54803 G43R Disease Neutral P54803 I583S Disease Disease P54803 N279T Disease Disease P54803 D528N Disease Neutral P54803 Y298C Disease Disease P54803 G268S Disease Disease P54803 A247T Disease Neutral P54803 R168C Neutral Neutral P54803 W410G Disease Disease P54803 R380W Disease Neutral P54803 A625T Neutral Neutral P54803 A576S Disease Neutral P54803 Y319C Disease Disease P54803 G537R Disease Disease P54803 T652R Disease Disease P54803 R515H Disease Disease P54803 D232N Neutral Disease P54803 S52F Disease Disease P54803 G178A Disease Neutral P54803 T452S Disease Disease P54803 I546T Neutral Neutral P54803 M101L Disease Neutral P54803 T513M Disease Neutral P54803 I234T Disease Disease P54803 I66M Disease Neutral P54803 Y551S Disease Disease P54803 R63H Disease Disease P54803 L618S Disease Disease P54803 L629R Disease Disease P54803 D171V Disease Disease P54803 V550G Disease Disease Q9NWH7 R333W Neutral Neutral Q9NWH7 C478Y Neutral Neutral O94880 R115K Neutral Neutral Q15392 Y471S Disease Disease Q15392 K306N Disease Disease Q15392 E191K Disease Disease Q15392 N294T Disease Neutral Q9UBU2 R146Q Neutral Neutral Q68BL7 T309A Neutral Neutral Q68BL7 R425Q Neutral Neutral Q9NZP8 I285V Neutral Neutral Q9Y223 A630T Disease Disease Q9Y223 R246W Disease Neutral Q9Y223 A631T Disease Disease Q9Y223 R266W Disease Neutral Q9Y223 I587T Disease Neutral Q9Y223 R162C Disease Disease Q9Y223 V216A Disease Neutral Q9Y223 A460V Disease Neutral Q9Y223 A524V Disease Disease Q9Y223 Y675H Disease Neutral Q9Y223 D225N Disease Neutral Q9Y223 R266Q Disease Neutral Q9Y223 V696M Disease Neutral Q9Y223 M171V Disease Disease Q9Y223 I557T Disease Neutral Q9Y223 C303V Disease Neutral Q9Y223 M712T Disease Disease Q9Y223 R177C Disease Disease Q9Y223 V572L Disease Neutral Q9Y223 D378Y Disease Neutral Q9Y223 D176V Disease Disease Q9Y223 R263L Disease Disease Q9Y223 R306Q Disease Neutral Q9Y223 H132Q Disease Disease Q9Y223 G576E Disease Disease Q9Y223 P36L Disease Neutral Q9Y223 G206S Disease Neutral Q9Y223 F528C Disease Disease Q9Y223 A631V Disease Disease Q9Y223 I472T Disease Disease Q9Y223 V331A Disease Disease Q9Y223 A600T Disease Disease Q9Y223 P27S Disease Neutral Q9Y223 R246Q Disease Neutral Q9Y223 N519S Disease Disease Q9Y223 I200F Disease Disease Q4AC94 R1832G Neutral Neutral Q4AC94 P773R Neutral Neutral Q4AC94 Q1219R Neutral Neutral Q4AC94 G1831W Neutral Neutral Q4AC94 S1663N Neutral Neutral Q4AC94 Y1297C Neutral Neutral Q4AC94 R997Q Neutral Neutral P12259 R334T Disease Neutral P12259 C613R Disease Disease P12259 Y1730C Disease Disease P12259 R2102H Disease Disease P12259 R2102C Disease Disease Q9HBK9 M287T Neutral Neutral Q9HBK9 T306I Neutral Disease Q9HBK9 R173W Neutral Disease O14653 R67K Neutral Neutral Q03692 G545R Neutral Disease Q03692 L614P Disease Disease Q03692 M27T Neutral Neutral Q03692 S600P Disease Disease Q03692 Y598D Disease Disease Q03692 R198H Neutral Disease Q03692 L644R Disease Disease Q03692 Q653P Disease Disease Q03692 C591R Disease Disease Q03692 W651R Disease Disease Q03692 G18R Disease Disease Q03692 V603M Neutral Disease Q03692 Y597H Disease Disease Q03692 G595E Disease Disease Q03692 G18E Disease Disease Q03692 Y582D Disease Disease Q03692 D648G Disease Disease Q03692 N617K Disease Disease Q03692 G618V Disease Disease Q03692 Y597C Disease Disease Q03692 G595R Disease Disease Q03692 S671P Disease Disease Q9Y581 F80L Neutral Neutral Q92530 F36C Neutral Neutral Q92530 H174R Neutral Neutral Q53TN4 S266N Neutral Neutral Q53TN4 R226H Disease Disease Q53TN4 M156T Neutral Disease P55157 Q244E Neutral Neutral P55157 S590I Disease Neutral P55157 H297Q Neutral Neutral P55157 E354Q Neutral Neutral P55157 I128T Neutral Neutral P55157 D384A Neutral Neutral P55157 Q95H Neutral Neutral P55157 G746E Disease Disease P55157 V168I Neutral Neutral P55157 R540H Disease Disease P55157 N780Y Disease Disease Q8IXB1 Y414C Neutral Neutral Q8IXB1 D76N Neutral Disease Q8IXB1 H646Q Neutral Neutral Q9NZL9 A293T Neutral Neutral Q6U949 T150A Neutral Neutral Q6U949 F125V Neutral Neutral Q6U949 P112T Neutral Neutral Q6U949 S106I Neutral Neutral Q8NBI3 L37F Neutral Neutral O95256 V350I Neutral Neutral P03886 A4T Disease Neutral P03886 L288P Neutral Disease P03886 M31T Disease Disease P03886 S205P Neutral Disease P03886 T87A Neutral Neutral P03886 Y277C Neutral Neutral P03886 L285P Disease Disease P03886 Y304H Disease Neutral P03886 T168A Neutral Neutral P03886 A52T Disease Neutral P03886 Y255C Neutral Disease P03886 M31V Disease Disease P03886 Y30H Disease Disease Q7LGC8 R357Q Neutral Neutral Q7LGC8 I348M Neutral Neutral Q7LGC8 R304Q Disease Disease Q5TBB1 K162T Disease Neutral Q5TBB1 V185G Disease Disease Q5TBB1 L60R Disease Disease Q5TBB1 T163I Disease Neutral Q5TBB1 H86R Disease Neutral Q5TBB1 A177T Disease Neutral Q5TBB1 Y219H Disease Disease Q9Y5B0 T340M Neutral Neutral Q9Y5B0 L755S Neutral Neutral Q9Y281 A35T Disease Neutral O15178 G177D Neutral Neutral O15178 E402K Neutral Neutral O60806 S128F Disease Disease O15178 N369S Neutral Neutral O15178 G356S Neutral Neutral O15178 V367M Neutral Neutral Q9P0M2 S193N Neutral Neutral Q9P0M2 E4K Neutral Neutral Q8TCD1 P37H Neutral Neutral Q96JM7 T183N Neutral Neutral P22792 W509R Neutral Neutral P22792 A305T Neutral Neutral P22792 V536M Neutral Neutral O43781 M239L Neutral Neutral P29323 M883V Disease Neutral P29323 D678N Neutral Disease P29323 I361V Neutral Neutral P29323 C289G Neutral Disease P29323 R199H Disease Neutral P29323 H679N Disease Disease P29323 V650A Disease Disease P29323 I909M Disease Neutral P29323 R844W Neutral Disease P29323 A279S Disease Neutral Q7LBE3 V744M Neutral Neutral O43511 V480D Disease Disease O43511 A372V Disease Disease O43511 K369E Disease Neutral O43511 G672E Disease Disease O43511 T410M Disease Disease O43511 T132I Disease Disease O43511 F335L Disease Neutral O43511 Y556C Disease Disease O43511 A411P Disease Disease P40879 C307W Neutral Disease P40879 P131R Disease Disease O43511 I490L Disease Disease O43511 L117F Disease Disease O43511 Y105C Disease Disease O43511 Q446R Disease Disease O43511 C565Y Disease Disease O43511 F667C Disease Disease O43511 S28R Disease Disease Q9BXS9 V206M Neutral Neutral O43511 G209V Disease Disease O43511 A106D Disease Disease O43511 Y530S Disease Disease O43511 Q514R Disease Neutral O43511 G139A Disease Disease P40879 H124L Disease Disease O43511 L597S Disease Disease O43511 Y78C Disease Disease O43511 Y530H Disease Neutral O43511 R409H Disease Disease O43511 G740S Neutral Neutral O43511 S552I Disease Disease O43511 G497S Disease Disease O43511 Y556H Disease Neutral O43511 N392Y Disease Disease O43511 T416P Disease Disease O43511 S252P Disease Disease O43511 V239D Disease Disease P40879 G120S Disease Disease O43511 S137P Disease Disease O43511 S133T Disease Disease O43511 L445W Disease Disease Q7LBE3 H748R Neutral Neutral O43511 V653A Disease Neutral O43511 S90L Disease Disease O43511 E29Q Disease Neutral O43511 G102R Disease Disease O43511 N457K Disease Disease O43511 V138F Disease Disease O43511 T508N Disease Neutral O43511 M147V Disease Disease P40879 D468V Disease Disease O43511 L236P Disease Disease O43511 T193I Disease Disease O43511 D724N Disease Disease O43511 I455F Disease Disease O43511 E384G Disease Disease O43511 S694P Disease Disease O43511 L676Q Disease Disease O43511 T721M Disease Disease O43511 R776C Disease Neutral O43511 D271H Disease Disease O43511 S391N Disease Disease O43511 P123S Disease Disease O43511 V609G Disease Neutral O43511 R409P Disease Disease P40879 S206P Disease Disease O43511 S666F Disease Disease O43511 H723R Disease Disease P14679 A206T Disease Disease P14679 M426K Disease Disease P14679 H404N Disease Neutral P14679 V318E Disease Disease P14679 R402Q Neutral Neutral P14679 V427G Disease Disease P17643 R326H Neutral Neutral P14679 E398A Disease Neutral P14679 S329P Disease Disease P14679 G47V Disease Disease P14679 S192Y Neutral Disease P14679 A355E Disease Neutral P14679 R299S Disease Disease P14679 R239W Disease Disease P14679 W400L Disease Disease P14679 S424F Disease Neutral P14679 K142N Neutral Disease P14679 R434I Disease Neutral P14679 G346E Disease Disease P14679 E328Q Disease Disease P14679 P205T Disease Disease P14679 S79L Disease Disease P14679 P152S Disease Neutral P14679 R422Q Disease Disease P14679 R405L Disease Neutral P14679 N371T Disease Disease P14679 Q68H Disease Disease P14679 Q378K Disease Neutral P14679 G253R Disease Disease P14679 M370T Disease Disease P14679 D240V Disease Disease P14679 W236L Disease Disease P14679 C89R Disease Disease P14679 R402L Disease Disease P14679 R299H Disease Disease P14679 V393F Disease Disease P14679 R308T Neutral Neutral P14679 A201S Disease Disease P14679 N371Y Disease Disease P14679 R217G Disease Neutral P14679 P431L Disease Disease P14679 E409D Disease Neutral P14679 A416S Disease Disease P14679 W80R Disease Disease P14679 F439V Disease Disease P14679 S361R Disease Disease P14679 T325A Disease Neutral P14679 E294G Disease Disease P14679 F176I Disease Disease P14679 S395R Disease Disease P14679 G97R Disease Disease P14679 C36Y Disease Disease P14679 S380P Disease Disease P14679 K243T Disease Neutral P14679 W236S Disease Disease P14679 S44R Disease Disease P14679 S44G Disease Neutral P14679 G109R Disease Disease P14679 V275F Disease Disease P14679 D444G Disease Disease P14679 P406L Disease Neutral P14679 M179L Disease Neutral P14679 P21S Disease Disease P14679 T373K Disease Disease P14679 D42G Disease Disease P14679 S395N Disease Neutral P14679 G446S Disease Disease P14679 M332T Disease Neutral P14679 E345G Disease Disease P14679 E398V Disease Disease P14679 H390D Disease Disease P14679 P417H Disease Disease P14679 H180N Disease Disease P14679 G419R Disease Disease P14679 R403S Disease Disease P14679 G47D Disease Disease P14679 L216M Disease Neutral P14679 D383N Disease Disease P14679 R217W Disease Neutral P14679 R77Q Disease Disease P14679 H256Y Disease Neutral P14679 S339G Disease Disease P14679 R217S Disease Neutral P14679 F134C Neutral Disease P14679 T155S Disease Disease P14679 A355P Disease Neutral P14679 W272C Disease Disease P14679 R402G Disease Disease P14679 D448N Disease Neutral P14679 C289R Disease Disease P14679 R217Q Disease Neutral P14679 V177F Disease Disease P14679 N382K Disease Disease P14679 R77W Disease Disease P14679 L288S Disease Disease P14679 N435D Disease Disease P14679 P81L Disease Disease P17643 R356Q Disease Disease P14679 D199N Disease Disease P14679 Q408H Disease Neutral P14679 C55Y Disease Disease P14679 H19Q Disease Neutral P14679 C289G Disease Disease Q15032 M270V Neutral Neutral Q15032 Q632P Neutral Neutral Q8TC36 A174T Neutral Neutral Q8TC36 E16K Neutral Neutral Q8TC36 E39D Neutral Neutral Q6P5W5 T114A Neutral Neutral Q6P5W5 G330D Disease Disease Q6P5W5 R251W Disease Neutral Q6P5W5 Q303H Disease Disease Q6P5W5 N106K Disease Neutral Q6P5W5 R95C Disease Disease Q6P5W5 G374R Disease Disease Q6P5W5 G526R Disease Disease Q6P5W5 L410P Disease Disease Q6P5W5 A357T Neutral Neutral Q6P5W5 L372P Disease Disease Q6P5W5 P200L Disease Disease Q6P5W5 T58A Neutral Neutral Q6P5W5 G630R Disease Disease Q6P5W5 C309Y Disease Disease Q6P5W5 P84L Disease Neutral O60844 T162S Neutral Neutral O60844 S32G Neutral Neutral P13611 G428D Neutral Neutral P13611 R1826H Neutral Neutral P13611 D2937Y Neutral Neutral P13611 V2315L Neutral Neutral P13611 K1516R Neutral Neutral P13611 S300L Neutral Disease P13611 F2301Y Neutral Neutral P13611 N3011K Neutral Neutral Q99795 D20N Neutral Neutral Q02413 N493T Neutral Neutral Q02413 T498N Neutral Neutral Q02413 Y841F Neutral Neutral Q96JI7 S463F Neutral Neutral Q96JI7 Y396C Neutral Neutral Q9H094 L459V Neutral Neutral Q9H094 Y114C Neutral Disease Q9BZV2 T422A Disease Disease Q9BZV2 G23V Disease Disease Q5VT99 K292E Neutral Neutral Q5VT99 L276F Neutral Neutral Q9NPL8 N76D Neutral Neutral O60279 L52F Neutral Neutral O60279 E390D Neutral Neutral O60279 R228K Neutral Neutral Q13439 Q1028K Neutral Neutral Q13439 N1552S Neutral Neutral Q68DN1 S1500F Neutral Neutral Q68DN1 T655S Neutral Neutral Q68DN1 R357G Neutral Neutral Q68DN1 V685A Neutral Neutral Q68DN1 A660E Neutral Neutral Q68DN1 D505V Neutral Neutral Q68DN1 I767T Neutral Disease Q68DN1 S1665P Neutral Neutral Q68DN1 N1613S Neutral Neutral Q68DN1 I774V Neutral Neutral Q68DN1 H1559Y Neutral Neutral P61758 M123V Neutral Neutral Q6IA69 V74L Neutral Neutral Q96C74 N103K Neutral Neutral Q96C74 R156P Neutral Neutral Q8WWY3 A216P Disease Disease Q8WWY3 A194E Disease Disease Q6L8Q7 R23W Neutral Neutral O15120 L228P Disease Disease O15120 G136R Disease Disease O15120 A239V Disease Neutral Q14210 A10T Neutral Neutral Q6UE05 A70D Neutral Neutral Q6UE05 W78R Neutral Neutral Q6UE05 I14N Neutral Disease P42701 M365T Neutral Neutral P42701 Q214R Neutral Neutral P42701 H339Q Neutral Neutral P42701 R213W Disease Neutral P42701 R156H Neutral Neutral P42701 P3Q Neutral Neutral P42701 P47S Neutral Neutral P42701 G378R Neutral Neutral Q15582 R555Q Disease Neutral Q15582 H626R Disease Disease Q15582 A546T Disease Disease Q15582 H626P Disease Disease Q15582 R666S Disease Neutral Q15582 V505D Disease Disease Q15582 T538R Disease Disease Q15582 R124C Disease Neutral Q15582 L518P Disease Disease Q15582 R124H Disease Neutral Q15582 N622K Disease Disease Q15582 F540S Disease Disease Q15582 H572R Disease Disease Q15582 R124S Disease Neutral Q15582 R124L Disease Neutral Q15582 P551Q Disease Disease Q15582 R555W Disease Disease Q15582 R496G Neutral Neutral Q15582 L569R Disease Disease Q15582 L518R Disease Disease Q15582 L269F Neutral Disease Q15582 P501T Disease Disease Q15582 I200F Neutral Disease Q15582 G623D Disease Disease Q15582 A546D Disease Disease Q15582 L509R Disease Disease Q15582 L527R Disease Disease P19838 M506V Neutral Neutral P19838 H711Q Neutral Neutral P19838 R578K Neutral Neutral P19838 A901T Neutral Neutral P19838 T489I Neutral Neutral P19838 T566I Neutral Neutral O75083 I185V Neutral Neutral Q8N0X4 I241V Neutral Neutral Q8N0X4 D28Y Neutral Neutral Q8N0X4 V128I Neutral Neutral Q96HJ9 S8A Neutral Neutral Q96IL0 A14P Neutral Neutral Q96IL0 N75S Neutral Neutral Q9BTV7 T428K Neutral Neutral O60885 S563N Neutral Neutral O60885 R669H Neutral Disease O60885 A371G Neutral Disease O60885 T598S Neutral Neutral O60885 P37S Neutral Neutral P07951 Q147P Disease Disease P06753 M8R Disease Disease P09493 E180G Disease Disease P09493 A63V Disease Neutral P09493 D175N Disease Disease P07951 R91G Disease Disease P09493 E180V Disease Disease P07951 E117A Disease Neutral Q7Z6A9 L267P Neutral Disease Q7Z6A9 S157R Neutral Neutral P08590 E143K Disease Disease P08590 R154H Disease Disease P08590 M149V Disease Disease P08590 E56G Disease Disease Q96LS8 P90L Neutral Neutral Q96M69 D302Y Neutral Neutral Q96M69 A661V Neutral Neutral Q16637 S262I Disease Neutral Q16637 I116F Disease Neutral Q16637 G279V Disease Disease Q16637 A111G Disease Neutral Q16637 A2G Disease Neutral Q16637 G279C Disease Disease Q16637 S262G Disease Neutral Q16637 G95R Disease Disease Q16637 T274I Disease Disease Q16637 Y272C Disease Disease Q16637 Q136E Disease Neutral Q16637 D44V Disease Disease Q16637 D30N Disease Neutral Q16637 G275S Disease Disease Q16637 P245L Disease Neutral Q13286 L170P Disease Disease Q13286 R334H Disease Disease Q13286 V330F Disease Disease Q13286 L101P Disease Disease Q13286 E295K Disease Disease Q13286 R334C Disease Disease Q5U649 N103K Neutral Neutral Q5U649 K51R Neutral Neutral Q5U649 K65R Neutral Neutral Q9Y375 R31L Neutral Neutral Q9Y375 A314G Neutral Neutral Q9Y375 R9H Neutral Neutral Q9Y375 E176K Neutral Neutral Q9UGN4 R111Q Neutral Neutral Q8TDQ1 R218Q Neutral Neutral Q8TDQ1 A19V Neutral Neutral Q17RM4 R534Q Neutral Neutral Q5XKL5 K136R Neutral Neutral P10144 Q55R Neutral Neutral P17538 T250A Neutral Neutral P06870 Q145E Neutral Neutral Q15661 R216Q Neutral Neutral P23946 H66R Neutral Disease P07477 A16V Disease Disease O43240 P149L Neutral Neutral P40313 H173R Neutral Neutral P07477 E79K Disease Neutral P23946 R98H Neutral Neutral P00746 V213G Disease Disease Q9Y5K2 Q197H Neutral Disease P15157 K221Q Neutral Neutral P06870 R77H Neutral Neutral P08861 W79R Neutral Neutral P20151 V18L Neutral Neutral P08246 G32V Disease Disease P07477 N29T Disease Neutral P20718 R84Q Neutral Disease Q9Y5K2 S22A Neutral Neutral Q15661 D162N Neutral Neutral P00746 C214R Disease Disease Q9UBX7 G49E Neutral Disease P00746 I248M Neutral Disease P07477 L104P Disease Disease Q15661 T215S Neutral Neutral P07477 D22G Disease Neutral P08246 V219I Neutral Neutral P07477 C139F Disease Disease P08246 P262L Neutral Neutral P07477 N29I Disease Disease P08246 V98L Neutral Neutral P24158 V119I Neutral Neutral P23946 G46R Neutral Disease P08246 P257L Neutral Neutral P12544 T121M Neutral Neutral P07288 L132I Neutral Neutral P24158 T136S Neutral Neutral Q9UBX7 R166C Neutral Neutral P08246 V177F Disease Neutral Q15661 N132K Neutral Neutral P06870 E186K Neutral Neutral Q15661 P170S Neutral Neutral P06870 V193E Neutral Disease P07477 R122C Disease Neutral P10144 Y247H Neutral Neutral P07477 K23R Disease Neutral P07477 N54S Disease Neutral Q15661 G23V Neutral Disease O43240 A50S Neutral Neutral Q9Y5K2 G159D Neutral Disease P08246 V101L Neutral Neutral Q15661 T141A Neutral Neutral P20151 R250W Neutral Disease P08246 R191Q Disease Neutral P24158 A135T Neutral Neutral P07477 R116C Disease Neutral Q99895 R80W Neutral Disease P07288 E32K Neutral Neutral Q15661 A85T Neutral Neutral P08311 N125S Neutral Neutral Q15661 A18V Neutral Neutral P07477 R122H Disease Neutral Q96D59 T82A Neutral Neutral Q96D59 R114Q Neutral Neutral Q14376 R239W Disease Disease Q14376 E165K Disease Disease Q14376 L183P Disease Disease Q14376 N34S Disease Disease Q14376 G302D Disease Disease Q14376 R335H Disease Disease Q14376 A25V Disease Disease Q14376 R169W Disease Disease Q14376 D103G Disease Neutral Q14376 K257R Disease Neutral Q14376 G319E Disease Disease Q14376 L313M Disease Disease Q14376 G90E Disease Disease Q14376 D69E Disease Disease Q14376 V94M Disease Disease Q14376 A180V Neutral Neutral Q14376 R40C Disease Disease P53621 V1040G Neutral Disease P16144 C38R Disease Disease P16144 V325D Disease Disease P16144 R1225H Disease Neutral P16144 G931D Disease Neutral P16144 D131Y Disease Disease P16144 R844L Neutral Neutral P16144 L336P Disease Disease P16144 R1281W Disease Disease P16144 L156P Disease Disease P16144 H1216Q Neutral Neutral P16144 C61Y Disease Disease P16144 G273D Disease Disease P16144 P1779L Neutral Neutral P16144 R283C Disease Disease P16144 C562R Disease Disease P16144 R252C Disease Disease P16144 Q478H Neutral Neutral P16144 C245G Disease Disease P16144 R98H Neutral Neutral Q96A22 T23R Neutral Neutral Q1ZYL8 A2T Neutral Neutral Q99466 G534S Neutral Neutral Q99466 P206L Neutral Neutral Q99466 S244L Neutral Neutral Q99466 K117Q Neutral Disease Q99466 K851R Neutral Neutral Q99466 D272G Neutral Neutral Q99466 T320A Neutral Neutral Q99466 E317Q Neutral Neutral Q99466 P204L Neutral Neutral Q16671 D426G Disease Neutral Q16671 G142V Disease Neutral Q16671 H282Q Disease Disease Q16671 R504C Disease Disease Q16671 D491H Disease Disease Q16671 R54C Disease Disease Q16671 R406Q Disease Neutral Q16671 V458A Disease Disease Q7Z3E5 R222H Neutral Neutral Q7Z3E5 L108F Neutral Neutral Q7Z3E5 I209T Neutral Neutral Q7Z4H7 S761I Neutral Neutral Q7Z4H7 H674Q Neutral Neutral Q969T7 C205S Neutral Neutral Q969T7 V201A Neutral Neutral Q8IZ08 Q5P Neutral Neutral Q96P64 E661K Neutral Disease Q14135 M32I Neutral Neutral Q6P2H3 A542T Neutral Neutral Q9NW15 V583A Neutral Neutral Q9NW15 R462Q Neutral Neutral Q9NW15 T561M Neutral Neutral Q07343 S703C Neutral Neutral Q01484 E3898K Disease Neutral Q01484 T3711N Disease Neutral Q01484 R3873W Disease Disease Q01484 L3707I Disease Neutral Q01484 E1425G Disease Neutral Q9HAD4 V329I Neutral Neutral Q9HAD4 R260C Neutral Neutral Q9HAD4 G61D Neutral Disease Q9UHJ6 E215K Neutral Neutral P13716 A274T Disease Disease P13716 G133R Disease Disease P13716 R240W Disease Disease P13716 V275M Disease Neutral P13716 K59N Neutral Neutral P13716 V153M Disease Neutral Q12882 C29R Neutral Neutral Q12882 R235W Neutral Disease Q12882 I543V Neutral Neutral Q12882 S534N Neutral Disease Q12882 R886H Neutral Disease Q12882 V732I Neutral Neutral Q12882 V995F Neutral Disease Q658N2 H212Y Neutral Neutral Q5JTZ9 A484D Neutral Neutral P49588 G275D Neutral Disease Q5JTZ9 I339V Neutral Neutral P57057 I414V Neutral Neutral P57057 D247N Neutral Disease O15353 R69C Neutral Neutral O15353 A599P Neutral Neutral O15353 R411W Neutral Neutral O15353 A283V Neutral Disease O15357 A1083G Neutral Neutral O15357 V721M Neutral Disease O15357 G1114A Neutral Neutral Q8NFJ6 L173R Disease Disease Q8NFJ6 V331M Neutral Disease Q8NFJ6 W178S Disease Neutral Q8NFJ6 T335M Neutral Disease Q8NFJ6 Q210R Disease Neutral Q8NFJ6 R85C Neutral Disease Q8NFJ6 R268C Neutral Neutral Q8NFJ6 R85H Disease Disease Q8TCW9 S40G Neutral Neutral Q8NFJ6 R164Q Disease Disease Q8NFJ6 P290S Disease Disease Q8NFJ6 M323I Disease Disease P20800 F131L Neutral Neutral P20800 P168L Neutral Neutral Q96F46 A367V Neutral Neutral Q96F46 R580H Neutral Neutral Q96KJ9 R161H Neutral Neutral Q8IZF2 T856M Neutral Neutral Q8IZF2 M604T Neutral Neutral Q9BZ19 R295C Neutral Disease O15182 V10L Neutral Neutral Q9Y6K9 R319Q Disease Neutral Q9Y6K9 D406V Disease Disease Q9Y6K9 E315A Disease Neutral Q9Y6K9 D113N Disease Neutral Q9Y6K9 M407V Disease Neutral Q9Y6K9 D311N Disease Neutral Q9Y6K9 R123W Disease Neutral Q9Y6K9 C417F Disease Disease Q9Y6K9 R173G Disease Neutral Q9Y6K9 A323P Disease Neutral Q9Y6K9 C417R Disease Disease Q9Y6K9 R175P Disease Neutral Q9Y6K9 A288G Disease Neutral Q9Y6K9 L227P Disease Disease Q9Y6K9 L153R Disease Disease Q9Y6K9 E57K Disease Neutral Q9Y6K9 C417Y Disease Disease Q6JBY9 Q384R Neutral Neutral P84996 P374T Disease Neutral P84996 L397V Disease Neutral Q07065 A348T Neutral Neutral P57071 S1481P Neutral Neutral P57071 T1376S Neutral Neutral P57071 V1342I Neutral Neutral Q5D0E6 R299Q Neutral Neutral Q9HCK1 R160K Neutral Neutral Q6UXA7 V81A Neutral Neutral Q6UXA7 N43D Neutral Neutral Q6UXA7 K165E Neutral Neutral Q6UXA7 L40F Neutral Neutral Q6UXA7 A145P Neutral Neutral Q6UXA7 G291D Neutral Neutral Q6UXA7 A83P Neutral Neutral Q6V0I7 P4972S Neutral Neutral Q6V0I7 G3524D Neutral Disease Q6V0I7 S3873N Neutral Neutral Q6V0I7 D2826N Neutral Disease Q6V0I7 A4977T Neutral Neutral Q6V0I7 K3828E Neutral Neutral Q6V0I7 E4374K Neutral Neutral Q13144 E650K Disease Disease Q13144 R113H Disease Neutral Q13144 W628R Disease Disease Q13144 T91A Disease Neutral Q13144 V430A Disease Neutral Q13144 I587V Neutral Neutral Q13144 L106F Disease Neutral Q13144 R339W Disease Disease Q13144 G386V Disease Disease Q13144 R315G Disease Neutral Q13144 V73G Disease Disease Q13144 R339P Disease Disease Q13144 R315H Disease Neutral Q13144 R339Q Disease Disease Q13144 R299H Disease Disease Q13144 R195H Disease Disease Q8TF27 I82V Neutral Neutral P08294 A91T Neutral Neutral P08294 R231G Neutral Neutral P08294 A58T Neutral Neutral Q8TD46 R89K Neutral Neutral Q8TD46 E312Q Neutral Neutral Q8TD46 Q177H Neutral Neutral Q8TD46 P121T Neutral Neutral Q96HY7 R308L Neutral Neutral Q96HY7 Y272D Neutral Disease Q96HY7 I607M Neutral Disease Q96HY7 L20F Neutral Neutral Q96HY7 N350D Neutral Neutral Q96HY6 A303T Neutral Neutral P04424 R379C Disease Disease P04424 R95C Disease Disease P04424 R193Q Disease Disease P04424 R111W Disease Disease P04424 Q286R Disease Disease P04424 R385C Disease Disease P04424 V178M Disease Neutral Q9NXG0 I695T Neutral Neutral Q9NXG0 T1376A Neutral Neutral Q9NXG0 R562C Neutral Neutral Q7Z4R2 P27T Neutral Neutral Q14117 R490T Disease Disease Q14195 A442S Neutral Neutral Q14194 V461I Neutral Neutral Q14117 W360R Disease Disease Q14117 Q334R Disease Disease Q14117 G435R Disease Disease Q14117 T68R Disease Disease Q9H040 P296L Neutral Neutral Q149N8 N1028Y Disease Disease Q149N8 S460F Disease Neutral Q149N8 Q438R Disease Neutral Q9H2C0 L309R Disease Disease Q9H2C0 R15S Disease Neutral Q9H2C0 C570Y Disease Disease Q9H2C0 R545C Disease Disease Q9H2C0 S52G Disease Disease Q9H2C0 I86F Disease Disease Q9H2C0 V82F Disease Disease Q9H2C0 E486K Disease Neutral Q9H2C0 G368R Disease Disease Q9H2C0 S79L Disease Disease Q9H2C0 I423T Disease Disease Q9H2C0 R138H Disease Neutral Q9H2C0 R269Q Disease Disease O14543 H125Y Neutral Neutral Q9BYE9 L1164M Neutral Neutral Q5U5Q3 T412P Neutral Disease P42898 P572L Disease Disease P42898 T227M Disease Disease P42898 E428A Neutral Neutral P42898 R157Q Disease Disease P42898 R51P Disease Disease P42898 P251L Disease Disease P42898 R519C Neutral Neutral P42898 E586K Disease Disease P42898 N324S Disease Disease P42898 R357C Disease Disease P42898 G387D Disease Disease P42898 E429A Neutral Neutral P42898 L323P Disease Disease P42898 R52Q Disease Neutral P42898 R325C Disease Disease P42898 T653M Neutral Neutral P42898 R335C Disease Disease P42898 R68Q Neutral Neutral P42898 R377C Disease Disease P42898 A222V Neutral Disease P42898 G422R Neutral Disease P42898 R594Q Neutral Neutral P42898 W339G Disease Disease Q02505 H2517Y Neutral Neutral Q02505 A2338V Neutral Neutral Q02505 H2517N Neutral Neutral P98171 A104V Neutral Neutral P98170 D242E Neutral Neutral P98170 S133F Neutral Disease P98170 Q423P Neutral Neutral P98170 N107S Neutral Neutral P00747 H133Q Neutral Disease P00747 V676D Neutral Neutral P00747 D472N Neutral Neutral P00747 I46R Neutral Neutral P00747 A620T Disease Disease P00747 R235H Disease Disease P00747 S591P Disease Disease P00747 R523W Neutral Neutral P00747 R408W Neutral Neutral P00747 V374F Disease Disease P00747 A494V Neutral Disease P00747 R261H Neutral Neutral P00747 R134K Neutral Neutral P00747 E57K Neutral Neutral P00747 K453I Neutral Neutral P63252 D172N Disease Neutral P63252 N216H Disease Disease P63252 V302M Disease Disease P63252 G300V Disease Disease P63252 R218W Disease Disease P63252 D71V Disease Disease P63252 R67W Disease Disease P63252 P186L Disease Disease Q14500 R6Q Neutral Neutral Q9UHL9 M652V Neutral Neutral Q86X83 Q177H Neutral Neutral Q86X83 I113L Neutral Neutral O60524 C257S Neutral Neutral Q8IYB8 P30T Neutral Neutral P27540 R430Q Neutral Disease P27540 D511N Neutral Neutral P27540 D517E Neutral Neutral P27540 P706L Neutral Neutral Q16570 A100T Neutral Neutral Q16570 G42D Neutral Neutral Q9Y2M0 G233E Neutral Neutral O75445 L555V Disease Disease O75445 R4115C Disease Disease O75445 C759F Disease Disease O75445 D644V Neutral Disease O75445 C319Y Disease Disease O75445 H610P Disease Neutral O75445 N346H Disease Neutral O75445 C163Y Disease Neutral O75445 R1486K Neutral Neutral O75445 R334W Disease Disease O75445 N3099S Neutral Neutral O75445 I2169T Neutral Neutral O75445 P761R Disease Neutral O75445 I1665T Neutral Neutral O75445 R2875Q Neutral Neutral O75445 R4674G Disease Disease O75445 D703E Neutral Neutral O75445 V218E Disease Disease O75445 A125T Neutral Neutral O75445 C419F Disease Disease O75445 S841Y Neutral Neutral O75445 N3199D Neutral Neutral O75445 I2106T Neutral Neutral O75445 T4425M Disease Disease O75445 T1515M Disease Neutral O75445 D3144N Neutral Neutral O75445 I3335M Neutral Neutral O75445 E478D Neutral Neutral O75445 C536R Disease Disease O75445 G713R Disease Disease O75445 V230M Disease Neutral O00754 R337Q Neutral Neutral O00754 T355P Disease Disease O00754 E402K Disease Neutral O00754 S453Y Disease Disease O00754 N413S Neutral Neutral O00754 R750W Disease Disease O00754 H72L Disease Disease O00754 L809P Disease Disease O00754 G801D Disease Disease O00754 W714R Disease Neutral O00754 P356R Disease Disease O00754 T312I Neutral Neutral O00754 H200L Disease Disease O00754 L278V Neutral Neutral P01189 D106N Neutral Neutral P01189 R236G Neutral Disease P01189 P62L Neutral Disease P01189 E214G Neutral Neutral P01189 S7T Neutral Neutral P01189 S9L Neutral Neutral P01189 P132A Neutral Neutral P01189 R236Q Neutral Disease Q3ZCQ2 R119Q Neutral Neutral Q3ZCQ2 R186W Neutral Neutral P07919 E51Q Neutral Neutral Q13277 E83D Neutral Neutral P32856 S42T Neutral Neutral O15457 A60V Neutral Neutral O15457 Y589C Neutral Disease O15457 A97T Neutral Neutral O15457 E162K Neutral Neutral O15457 S914N Neutral Neutral O15457 A90T Neutral Neutral Q8NAT9 M32R Neutral Neutral Q5T9Z0 Y130H Neutral Neutral Q5JVX7 V189I Neutral Neutral Q5JVX7 E85G Neutral Neutral Q9H0R4 R85Q Neutral Neutral Q9H008 Q94R Neutral Neutral A6NMW7 F533C Neutral Neutral A6NMW7 E836K Neutral Neutral P49716 R248W Neutral Disease Q9Y572 T300M Neutral Neutral Q9Y572 P492Q Neutral Neutral Q7Z4T9 S320C Neutral Neutral Q7Z4T9 S253T Neutral Neutral Q7Z4T9 P207A Neutral Neutral O60566 T40M Neutral Neutral O60566 R36Q Disease Disease O60566 E390D Neutral Neutral O60566 R550Q Disease Neutral O60566 M15T Disease Neutral O60566 V618A Disease Neutral O60566 R349Q Neutral Neutral O60566 I909T Disease Neutral O60566 L844F Disease Neutral O60566 L1012P Disease Disease O60566 R814H Disease Disease O60566 Q921H Disease Neutral Q9UMR7 H36L Neutral Neutral Q8IVF4 V480I Neutral Neutral P04629 P695L Disease Neutral P04629 L213P Disease Disease P04629 R654C Disease Disease P04629 L93P Disease Disease P04629 D674Y Disease Disease P04629 R649W Disease Disease P04629 G577R Disease Disease P04629 M587V Disease Neutral P04629 R780P Disease Disease P04629 G522R Disease Disease P04629 G714S Disease Disease Q6NVH7 D171G Neutral Neutral Q3LFD5 N325S Neutral Neutral Q3LFD5 Y130C Neutral Disease Q8TBF5 D197E Neutral Neutral Q8TBF5 P155L Neutral Disease P20933 F135S Disease Disease P20933 G252R Disease Neutral P20933 C163S Disease Disease P20933 G100E Disease Disease P20933 G252E Disease Disease P20933 C306R Disease Disease P20933 S149T Neutral Neutral P20933 G302R Disease Disease P20933 V12L Disease Neutral P20933 G60D Disease Neutral P20933 A101V Disease Disease P20933 T257I Disease Disease P20933 S72P Disease Disease P20933 R161Q Disease Neutral Q9UBM8 S428T Neutral Neutral Q92911 G543E Disease Disease Q92911 T354P Disease Disease Q92911 G93R Disease Disease Q92911 G395R Disease Disease Q92911 A102P Neutral Disease Q92911 Q267E Disease Disease Q8WTV0 V135I Neutral Neutral Q8WTV0 G167S Neutral Neutral Q8WTV0 G2S Neutral Neutral Q8WTV0 C511R Neutral Neutral Q8WTV0 S229G Neutral Neutral O15259 G342R Disease Disease Q2VWP7 I1062L Neutral Neutral Q9Y597 F9V Neutral Neutral P10912 R89K Disease Neutral P10912 V162F Neutral Disease P10912 I171T Disease Disease P10912 S244I Disease Disease P10912 V143A Disease Disease P10912 D170H Disease Disease P10912 C440F Disease Disease P10912 P579T Neutral Neutral P10912 F114S Disease Disease P10912 W68R Disease Disease P10912 V173G Disease Disease P10912 V162D Disease Disease P10912 R179C Disease Disease P10912 R229G Disease Disease P10912 I544L Neutral Disease P10912 Y226C Disease Disease P10912 E465K Neutral Disease P10912 S58L Disease Disease P10912 V162I Disease Neutral P10912 P495T Neutral Disease P10912 C56S Disease Disease P10912 R179H Neutral Neutral P10912 R229H Disease Disease P10912 E242D Disease Disease P10912 P149Q Disease Disease P10912 D262N Disease Neutral P10912 Q172P Disease Disease P10912 E62K Disease Disease P60891 L129I Disease Disease P60891 Q133P Disease Disease P60891 D183H Disease Disease P60891 N114S Disease Disease P60891 D52H Disease Disease P60891 H193Q Disease Disease P60891 A190V Disease Disease P60891 M115T Disease Disease P60891 E43D Disease Disease P60891 L152P Disease Disease Q8N5G0 A41T Neutral Neutral Q8N5G0 H76N Neutral Neutral Q8N5G0 S65N Neutral Neutral Q8N5G0 A109T Neutral Neutral Q2TBF2 T266I Neutral Neutral P16520 L280F Neutral Neutral P16520 G324E Neutral Disease P16520 W339L Neutral Disease P16520 G272S Neutral Neutral P16520 D76N Neutral Neutral Q9Y2T6 G195V Neutral Disease Q9HA77 E440K Neutral Neutral Q9HA77 Q555P Neutral Neutral Q8NCX0 E156K Neutral Neutral P05019 A187D Neutral Neutral Q9H2K0 T68I Neutral Neutral Q9H2K0 L243F Neutral Neutral Q53GS7 R590Q Neutral Neutral Q53GS7 G130D Neutral Disease Q53GS7 I243V Neutral Neutral Q9Y6G9 Q277R Neutral Neutral O43918 V80L Disease Neutral O43918 G228W Disease Disease O43918 P326L Disease Disease O43918 A21V Disease Neutral O43918 P326Q Disease Disease O43918 W78R Disease Disease O43918 P539L Disease Neutral O43918 Y90C Disease Disease O43918 S278R Neutral Neutral O43918 T16M Disease Disease O43918 K83E Disease Neutral O43918 F77S Disease Disease O43918 L29P Disease Disease O43918 C311Y Disease Disease O43918 P252L Disease Neutral O43918 G305S Neutral Disease O43918 L93R Disease Disease O43918 R15C Disease Neutral O43918 L28P Disease Disease O43918 R15L Disease Disease O43918 V301M Disease Disease O43918 Y85C Disease Disease P02748 C119G Disease Disease P02748 T279S Neutral Neutral P02748 I203V Neutral Neutral P02748 R5W Neutral Neutral O43934 S428F Neutral Neutral Q99683 D1315N Neutral Neutral Q99683 G1006R Neutral Neutral Q99683 I1250V Neutral Neutral Q99683 I1214T Neutral Neutral Q99683 T1314I Neutral Neutral Q9BSF8 T145A Neutral Neutral P19429 D196N Disease Neutral P19429 P82S Disease Neutral P19429 R145G Disease Disease P19429 D190H Disease Disease P19429 R162P Disease Disease P19429 R192H Disease Disease P19429 R79C Neutral Disease P19429 K206Q Disease Disease P19429 S166F Disease Disease P19429 L144Q Disease Disease P19429 A171T Disease Neutral P19429 R186Q Disease Neutral P19429 A157V Disease Disease P19429 K178E Disease Disease P19429 R141Q Disease Neutral P19429 R145W Disease Disease Q14790 S219T Neutral Neutral Q14790 D285H Neutral Neutral Q14790 R248W Disease Disease Q6MZN7 H123R Neutral Neutral Q6MZN7 V112G Neutral Neutral Q6MZN7 W82C Neutral Disease Q6MZN7 G93E Neutral Neutral Q6MZN7 W32R Neutral Neutral P50876 T4A Neutral Neutral Q86UC2 R398Q Neutral Neutral Q86UC2 M439T Neutral Disease Q86UC2 N201S Neutral Neutral Q86UC2 G518D Neutral Neutral Q86UC2 R213Q Neutral Neutral Q86UC2 E484K Neutral Neutral P42566 I822M Neutral Neutral Q92562 V654A Neutral Neutral Q92562 M364L Neutral Neutral Q92562 I41T Disease Disease Q8WU76 L512S Neutral Neutral Q6UW49 E191G Neutral Neutral Q6UW49 L133F Neutral Neutral Q71F23 G16S Neutral Neutral Q71F23 I157T Neutral Neutral Q71F23 I214M Neutral Neutral Q14814 P434S Neutral Neutral Q15020 E621D Neutral Neutral Q15020 V591M Disease Neutral Q15020 D23E Neutral Neutral Q149M9 G174S Neutral Neutral Q149M9 H935R Neutral Neutral Q149M9 I926N Neutral Disease Q149M9 Q900E Neutral Disease Q149M9 L211F Neutral Neutral Q149M9 D1541V Neutral Neutral Q149M9 T218A Neutral Neutral Q9H3T2 P455T Neutral Neutral O43361 A318T Neutral Neutral O43361 I684R Neutral Neutral O43361 Q156R Neutral Neutral O14974 K734N Neutral Neutral O60237 R836K Neutral Neutral O60237 V182I Neutral Neutral O14974 C116W Neutral Neutral O14974 T305P Neutral Neutral Q96GE4 M165I Neutral Neutral P43631 K237E Neutral Neutral Q14954 R91K Neutral Neutral Q9H4Z2 S294T Neutral Neutral P01258 S123T Neutral Neutral P01258 E67K Neutral Neutral P01258 G2R Neutral Neutral P01258 D57N Neutral Neutral P01258 S76R Neutral Neutral P01258 Q138P Neutral Neutral Q8N119 P115Q Neutral Disease Q8N119 A191V Neutral Neutral Q8N119 E349G Neutral Disease Q8N119 A95E Neutral Disease Q8N119 A454V Neutral Disease Q8N119 D263E Neutral Disease Q9NX55 S151P Neutral Neutral Q9HC84 T5137S Neutral Neutral Q9UJX2 E72Q Neutral Neutral Q9UJX2 P3L Neutral Neutral Q15475 Y129C Disease Disease Q15475 R110W Disease Disease Q03167 W163L Neutral Disease Q03167 S15F Neutral Neutral Q03167 A634T Neutral Neutral Q03167 S14N Neutral Neutral Q03167 G764R Neutral Neutral Q96S44 A25T Neutral Neutral Q96S44 R123Q Neutral Disease Q96S44 T129A Neutral Neutral Q96S44 T145A Neutral Neutral Q9NT68 V1719F Neutral Neutral Q6ZTQ4 Q61H Neutral Neutral Q6ZTQ4 C529Y Neutral Neutral Q6ZTQ4 V55M Neutral Neutral P29375 M865T Neutral Neutral P29375 P1190A Neutral Neutral A5YM72 P14T Neutral Neutral Q5VZT2 D100H Neutral Neutral Q5JYT7 P415L Neutral Neutral Q5JYT7 A633V Neutral Neutral Q5JYT7 K339N Neutral Neutral Q5JYT7 R1045W Neutral Neutral Q5JYT7 E940K Neutral Neutral O00505 P291S Neutral Neutral P52292 T430P Neutral Disease P52292 P165R Neutral Disease Q5SWA1 P26S Neutral Neutral Q5SWA1 N308S Neutral Neutral Q5SWA1 E144K Neutral Neutral Q5SWA1 K589E Neutral Neutral Q5SWA1 E363G Neutral Neutral P21128 E31V Neutral Neutral P21128 E31Q Neutral Neutral Q969Q1 K237E Neutral Neutral Q9H1M3 T149S Neutral Neutral Q9H1M0 T177I Neutral Neutral Q53FT3 P47A Neutral Neutral P05455 P48S Neutral Neutral Q9H503 T78S Neutral Neutral Q9H503 N3D Neutral Neutral Q14145 Q284L Disease Neutral Q14145 G430C Disease Disease Q14145 G364C Disease Disease Q14145 V167F Disease Disease Q14145 D349N Neutral Neutral Q96EB6 D3E Neutral Neutral Q13461 G196A Neutral Neutral Q13461 S300G Neutral Neutral O95447 G17S Neutral Neutral P36959 F256I Neutral Neutral P36959 A234T Neutral Disease Q8NAG6 P297T Neutral Neutral Q8NAG6 L170W Neutral Neutral Q8NAG6 V407M Neutral Neutral Q8NAG6 R395Q Neutral Neutral Q8NAG6 L80Q Neutral Disease O43556 L172R Disease Disease Q14160 E674V Neutral Neutral Q14160 L422P Neutral Neutral O43405 W117R Disease Disease O43405 V66G Disease Neutral O43405 I109N Disease Disease O43405 I402V Neutral Neutral O43405 G135R Neutral Neutral O43405 P532S Neutral Neutral O43405 G88E Disease Disease O43405 D281N Neutral Disease O43405 P51S Disease Disease O43405 A119T Disease Neutral O43405 T352S Neutral Neutral Q92625 L694S Neutral Neutral O43670 A224S Neutral Neutral Q13487 L118V Neutral Neutral Q9UQC2 P344L Neutral Neutral P02749 C325G Neutral Disease P02749 S107N Neutral Neutral P02749 W335S Neutral Disease P02749 V266L Neutral Neutral P02749 R154H Neutral Disease O15327 Y311F Neutral Disease Q16853 G700S Neutral Neutral Q16853 H167Y Neutral Neutral O75106 I5V Neutral Neutral Q16853 R441W Neutral Disease O75106 Y22C Neutral Neutral P19801 T16M Neutral Neutral O75106 R273Q Neutral Neutral Q16853 R426H Neutral Neutral Q16853 A408S Neutral Disease Q16853 T5R Neutral Disease P19801 M479I Neutral Disease Q16853 A749V Neutral Neutral Q16853 R329Q Neutral Neutral O75106 E427D Neutral Disease Q16853 A582T Neutral Neutral P19801 N659H Neutral Neutral P19801 S332F Neutral Disease Q16853 Y317H Neutral Neutral O75106 P141L Neutral Disease Q16853 I371T Neutral Neutral P19801 D645H Neutral Disease Q6UWB4 R44P Neutral Disease Q6UWB4 V212A Neutral Disease P49770 G329V Disease Disease P49770 S171F Disease Disease P49770 V316D Disease Disease P49770 E213G Disease Neutral P49770 K273R Disease Disease O15520 I156R Disease Disease O15520 C106F Disease Neutral Q9BZ23 T528M Disease Neutral Q9BZ23 L111Q Neutral Neutral Q9BZ23 L413P Disease Disease Q9BZ23 G521R Disease Disease Q9BZ23 R264W Disease Disease Q9BZ23 L282V Disease Disease Q9BZ23 R278C Disease Disease Q9BZ23 S351P Disease Disease Q9BZ23 I497T Disease Disease Q9BZ23 N355S Disease Disease Q9BZ23 T327I Disease Neutral Q9BZ23 R286C Disease Disease Q9BZ23 T234A Disease Disease Q9BZ23 G126A Neutral Neutral Q9BZ23 N404I Disease Disease Q9BZ23 S471N Disease Disease Q9BZ23 N500I Disease Disease Q9BZ23 G219V Disease Disease Q3V5L5 V70I Neutral Neutral Q53F39 V197M Neutral Neutral Q53F39 M336L Neutral Neutral Q53F39 P268A Neutral Neutral Q53F39 R138Q Neutral Disease Q9Y2Z9 V406M Neutral Neutral Q9Y2Z9 T395M Neutral Neutral Q9Y2Z9 D339V Neutral Disease Q9Y690 E193D Neutral Disease Q2VPK5 Q416R Neutral Neutral Q2VPK5 M253V Neutral Neutral Q2VPK5 V332I Neutral Neutral P09936 S18Y Neutral Neutral Q8NA66 Q69K Neutral Neutral Q8NA66 D64N Neutral Neutral Q3MIW9 R517Q Neutral Neutral Q3MIW9 E419K Neutral Neutral Q3MIW9 G337R Neutral Neutral P01588 P149Q Disease Neutral P43304 R525H Neutral Neutral Q9H161 R272P Disease Disease Q9H161 S102P Neutral Neutral Q9H161 R218Q Disease Disease Q9H161 T35R Neutral Neutral Q8TDS5 L407V Neutral Neutral Q96EL3 A4S Neutral Neutral Q96EL2 W97R Neutral Neutral Q13751 K207Q Disease Neutral Q13751 G199A Disease Neutral Q13751 P679L Disease Neutral Q13751 E210K Disease Disease Q8N7E2 D166E Neutral Neutral Q8N7E2 S287F Neutral Neutral Q03721 D318Y Neutral Disease Q03721 C520Y Neutral Neutral O14593 Q251E Neutral Neutral Q8IYT3 F324S Neutral Neutral Q8IYT3 A269V Neutral Neutral Q8IYT3 A331T Neutral Neutral Q8IYT3 V604I Neutral Neutral Q8IYT3 V683I Neutral Neutral Q6UXB8 L416V Neutral Neutral Q6UXB8 T50P Neutral Neutral Q5JSZ5 L981P Neutral Neutral Q5JSZ5 S936T Neutral Neutral P22557 I476N Disease Disease P22557 D159Y Disease Disease P22557 R448Q Disease Neutral P22557 R452C Disease Neutral P22557 T388S Disease Disease P22557 R204Q Disease Neutral P22557 R560H Disease Neutral P22557 Y199H Disease Neutral P22557 R411C Disease Disease Q9UPW0 A162V Neutral Neutral Q9UPW0 P377T Neutral Neutral Q969Y2 R368H Neutral Neutral Q969Y2 A250V Neutral Neutral Q15814 P180S Neutral Neutral Q15814 A279T Neutral Disease Q15814 A65V Neutral Neutral Q15814 G157D Neutral Neutral Q15814 P169S Neutral Neutral Q96JY0 S41A Neutral Neutral P27539 A118V Neutral Neutral Q9H9P8 H434P Disease Disease Q9H9P8 K81E Disease Disease Q9H9P8 P302L Disease Disease Q9H9P8 E176D Disease Disease Q9H9P8 H98R Disease Disease Q9H9P8 G57R Disease Disease Q9H9P8 H98Y Disease Disease Q9H9P8 R18L Neutral Neutral Q9H9P8 G55D Disease Disease Q9H9P8 Y178F Neutral Neutral Q9Y6J6 T8A Neutral Neutral Q9Y6J6 I57T Disease Disease Q9Y6J6 V65M Disease Neutral Q9Y6J6 Q9E Disease Neutral Q9Y6J6 R77W Disease Neutral Q9Y6J6 F60L Disease Neutral Q9Y6J6 A66V Neutral Neutral Q9Y6J6 T8I Neutral Disease Q9Y6J6 M54T Disease Disease Q9Y6J6 R27C Disease Disease P32189 N288D Disease Disease P32189 N232H Neutral Disease P32189 W503R Disease Disease P32189 S185N Neutral Disease P32189 D440V Disease Disease P32189 A376T Neutral Disease P02810 D66N Neutral Neutral P02810 D20N Neutral Neutral P02810 Q163K Neutral Neutral P02810 I42L Neutral Neutral P02810 R119C Neutral Neutral Q8IWS0 C99F Disease Disease Q8IWS0 H229R Disease Neutral Q8IWS0 K234E Disease Neutral Q8IWS0 C45Y Disease Disease Q8IWS0 R257G Disease Neutral P05160 R115H Neutral Disease P05160 Y543S Neutral Disease P05160 L529P Neutral Neutral P05160 D569E Neutral Neutral P05160 H350R Neutral Neutral P05160 M49V Neutral Neutral P05160 E388V Neutral Neutral P05160 I342T Neutral Disease Q13496 L202S Disease Disease Q13496 L470P Disease Disease Q13496 W346C Disease Disease Q13496 D433N Disease Neutral Q13496 Y198N Disease Disease Q13496 D431N Disease Neutral Q13496 L87P Disease Disease Q13496 P226T Disease Disease Q13496 I264S Disease Disease Q13496 R69P Disease Disease Q13496 G402R Disease Disease Q13496 N180K Disease Disease Q13496 A279G Disease Disease Q13496 R241C Disease Disease Q13496 S376N Disease Disease Q13496 V227M Disease Disease Q13496 V49F Disease Disease Q13496 W499R Disease Disease Q13496 G402A Disease Disease Q13496 R69S Disease Disease Q13496 A389D Disease Disease Q13496 Y397C Disease Disease Q13496 L70F Disease Disease Q13496 E157K Disease Disease Q13496 T186I Disease Disease Q13496 L228P Disease Disease Q13496 N189S Disease Disease Q13496 P205L Disease Disease Q13496 R184L Disease Disease Q13496 M317R Disease Disease Q13496 R184G Disease Disease Q13496 R421Q Disease Disease Q13496 P179S Disease Neutral Q13496 R241L Disease Disease Q13496 T197I Disease Disease Q13496 E404K Disease Disease Q13496 G378E Disease Disease Q13496 G378R Disease Disease Q13496 G402V Disease Disease Q13496 C444Y Disease Disease Q13496 H374D Disease Disease Q13496 W230C Disease Disease Q13496 R69C Disease Disease Q13496 I225T Disease Disease Q13496 H232R Disease Disease Q13496 S229P Disease Disease Q13496 K510N Disease Neutral Q13496 W411C Disease Disease Q13496 P199S Disease Disease Q13496 N481Y Disease Disease Q13496 V364G Disease Disease Q13496 W346S Disease Disease Q13496 Y68D Disease Disease Q13496 L391P Disease Disease Q13496 L406P Disease Disease Q13496 H469P Disease Disease P00414 V254I Neutral Neutral P00414 F35S Neutral Disease P00414 H3R Neutral Disease P00414 A200T Disease Disease P00414 Q177R Neutral Disease P00414 G78S Disease Disease P00414 V91I Neutral Neutral O43827 R140H Neutral Neutral O43827 E51D Neutral Neutral O43827 Q175H Neutral Disease Q9NQA5 R154H Neutral Neutral Q9NQA5 A563T Neutral Neutral Q9NQA5 L712F Neutral Neutral Q9H1D0 M378V Neutral Neutral Q9H1D0 C157R Neutral Disease Q9NQA5 A8V Neutral Neutral Q9H1D0 M681T Neutral Neutral Q14511 T577M Neutral Neutral O60313 T503K Disease Disease O60313 R571H Disease Neutral O60313 R290Q Disease Neutral O60313 A192V Neutral Neutral O60313 S545R Disease Disease O60313 G300E Disease Disease O60313 R445H Disease Disease O60313 P167L Neutral Neutral O60313 L396R Disease Disease O60313 N158S Neutral Neutral O60313 L939P Disease Disease Q08J23 V627I Neutral Neutral O75677 M127T Neutral Disease O75677 W94R Neutral Disease P49683 V283I Neutral Neutral P49683 D302G Neutral Neutral Q8TER5 S1189L Neutral Neutral Q8TER5 L956V Neutral Neutral Q8TER5 M1312T Neutral Neutral Q9Y6N9 E519D Neutral Neutral P32239 V125I Neutral Neutral P32239 R215H Neutral Neutral P32239 R319Q Neutral Neutral P32239 L37F Neutral Neutral O75807 A32T Neutral Neutral O75807 R251P Neutral Neutral O75807 A316P Neutral Neutral O75807 R594C Neutral Neutral O75807 K277E Neutral Neutral O75807 R31H Neutral Neutral O75807 V199A Neutral Neutral O75807 R476S Neutral Neutral O75807 A381V Neutral Neutral O75807 T597A Neutral Neutral Q8NFJ9 L503H Disease Neutral Q8NFJ9 Y434S Disease Disease Q8NFJ9 E234K Disease Neutral Q8NFJ9 L518P Disease Disease Q8NFJ9 M390R Disease Neutral Q8NFJ9 L518Q Disease Disease Q8NFJ9 H35R Disease Neutral Q8NFJ9 R160Q Disease Neutral Q8NFJ9 G305S Disease Neutral Q8NFJ9 K53E Disease Neutral Q8NFJ9 D148N Disease Neutral Q93063 M42V Neutral Neutral Q93063 D227N Disease Disease Q16394 R280G Disease Disease Q16394 P496L Disease Neutral Q16394 R340C Disease Disease Q93063 R223P Disease Disease Q93063 C85R Disease Disease Q93063 I380T Disease Disease Q16394 G339D Disease Disease Q16394 R340S Disease Disease Q16394 R280S Disease Disease Q16394 N316S Disease Neutral Q16394 A486V Disease Neutral Q16394 R340L Disease Disease Q93063 A202V Disease Neutral Q16394 R340H Disease Neutral Q93063 L152R Disease Disease Q93063 R179S Disease Neutral Q16394 D164H Disease Neutral Q16394 Q27K Disease Neutral P55198 A198T Neutral Neutral Q8WTU0 G239E Neutral Disease Q8WTU0 S142G Neutral Neutral Q8WTU0 G136S Neutral Neutral Q13610 L288F Neutral Disease P50613 G163A Neutral Neutral P50613 T285M Neutral Disease Q96QE3 P87S Neutral Neutral Q96QE3 R249K Neutral Neutral Q96QE3 E135G Neutral Neutral Q96QE3 N699H Neutral Neutral Q96QE3 T35S Neutral Neutral Q96QE3 Y1419H Neutral Neutral Q12872 P421L Neutral Neutral Q5T197 M512L Neutral Neutral O43866 D117E Neutral Disease P08123 G1012S Disease Disease P08123 T1148P Disease Disease P02461 G918E Disease Neutral P08123 G796S Disease Neutral P02461 G1014E Disease Disease P02452 G776S Disease Neutral P08123 G460S Disease Neutral P02461 G549E Disease Neutral P02452 G560S Disease Neutral P02461 G228E Disease Disease P02458 L667F Disease Neutral P02452 P1438R Neutral Disease P02452 G1154R Disease Disease P02458 G1110C Disease Disease P02461 G1173E Disease Disease P02461 G762C Disease Neutral P08123 T59P Neutral Neutral P02458 G1119R Disease Disease P02452 G809S Disease Neutral P02452 V1177I Neutral Neutral P02452 G569R Disease Neutral P02452 G1049S Disease Disease P02452 G719D Disease Neutral P02452 P205A Neutral Neutral P02458 G492V Disease Neutral P08123 V270I Neutral Neutral P02461 G264R Disease Disease P02452 G533D Disease Neutral P02452 G866S Disease Neutral P08123 P678H Neutral Neutral P08123 G973V Disease Disease P08123 G433E Disease Neutral P02461 G501R Disease Neutral P08123 A743G Neutral Neutral P08123 G955S Disease Disease P02461 G252D Disease Disease P08123 G715D Disease Neutral P02458 G948D Disease Neutral P08123 G787C Disease Neutral P08123 A483V Neutral Neutral P02452 G1091S Disease Disease P02461 G1182E Disease Disease P02452 G1181S Disease Disease P02461 G1188E Disease Disease P02452 G1025R Disease Disease P02461 G726R Disease Neutral P02461 G582S Disease Neutral P02452 G1151S Disease Disease P02461 G999R Disease Disease P02461 G666D Disease Neutral P02452 R312C Disease Neutral P02461 G444R Disease Neutral P02461 G924C Disease Neutral P02452 D1277H Disease Disease P02452 G1151V Disease Disease P02452 G422C Disease Neutral P08123 G562C Disease Neutral P02461 G252V Disease Disease P02461 G183S Disease Disease P08123 Q1354H Neutral Disease P02461 G1098V Disease Disease P02452 G1172D Disease Disease P02452 G434V Disease Neutral P02461 G210D Disease Disease P02461 G204S Disease Disease P02461 G957S Disease Disease P08123 G730C Disease Neutral P02461 G1164R Disease Disease P08123 G586R Disease Neutral P08123 L1022F Neutral Neutral P02452 G383C Disease Neutral P02461 G192V Disease Disease P02461 G1104A Disease Disease P08123 N528S Neutral Neutral P02461 G519V Disease Neutral P02461 G939D Disease Neutral P08123 G511D Disease Neutral P02461 G345R Disease Neutral P02458 T1448P Disease Disease P02461 G1185V Disease Disease P08123 G766V Disease Neutral P02452 A1075T Neutral Neutral P02461 G240R Disease Disease P02458 G780R Disease Neutral P02461 G756E Disease Neutral P02461 G852C Disease Disease P02452 L1464P Disease Disease P02458 A1051T Neutral Neutral P02452 G767S Disease Neutral P02461 G966V Disease Disease P02452 G1142S Disease Disease P02461 G960V Disease Disease P02452 G350R Disease Disease P02458 Y1391C Disease Disease P02461 G1071V Disease Disease P02458 R992G Disease Neutral P02452 G425S Disease Neutral P02458 C1485G Disease Disease P02452 G821S Disease Neutral P02458 G1188R Disease Disease P02461 G972A Disease Disease P08123 G637D Disease Neutral P02452 G851D Disease Neutral P02452 G743V Disease Neutral P08123 G997D Disease Disease P02461 G1050D Disease Disease P02458 G303D Disease Disease P02461 G936S Disease Neutral P02452 G560C Disease Neutral P02452 G1022S Disease Disease P02461 G183D Disease Disease P08123 G349C Disease Neutral P02452 G1019A Neutral Disease P08123 G892D Disease Disease P02452 G764V Disease Neutral P02458 G717V Disease Neutral P08123 G337C Disease Neutral P02458 G1170S Disease Disease P02461 G1188R Disease Disease P02461 G738V Disease Neutral P02461 G738S Disease Neutral P02461 G489E Disease Neutral P02452 G1187V Disease Disease P02452 K1430N Neutral Neutral P08123 P1101L Neutral Disease P02452 G1043S Disease Disease P02461 G540R Disease Neutral P02458 T9S Neutral Neutral P08123 G1102R Disease Disease P05997 G963R Disease Disease P08123 G334C Disease Neutral P02458 R904C Disease Neutral P02461 G225V Disease Disease P02461 G909V Disease Neutral P02452 G980V Disease Disease P08123 G949S Disease Disease P02458 G795R Disease Neutral P02452 R1141Q Neutral Neutral P02452 G398A Disease Neutral P02458 R565C Disease Disease P02452 G332R Disease Disease P02461 G699R Disease Neutral P08123 G784R Disease Neutral P02452 G1058S Disease Disease P08123 G211D Disease Disease P02452 P823A Neutral Neutral P08123 G835S Disease Neutral P02452 G272C Disease Disease P02461 G1098D Disease Disease P08123 D1189E Neutral Disease P02452 G476R Disease Neutral P02461 G657E Disease Neutral P02458 G1173R Disease Disease P02461 G1101E Disease Disease P08123 G337S Disease Neutral P02461 G327D Disease Neutral P02461 G804S Disease Neutral P02452 G1061S Disease Disease P02458 G894E Disease Neutral P08123 G1066D Disease Disease P02452 G704C Disease Neutral P08123 G778S Disease Neutral P02461 G249D Disease Disease P02452 G1106A Disease Disease P08123 G670D Disease Neutral P02452 G1082C Disease Disease P02461 G1077V Disease Disease P02461 G984T Disease Disease P02452 P1460H Neutral Disease P02461 G1167V Disease Disease P02461 G882D Disease Neutral P08123 G517R Disease Neutral P02461 G201R Disease Disease P02458 V1331I Neutral Neutral P02461 G996E Disease Disease P02461 G828W Disease Neutral P02458 G771D Disease Neutral P08123 G736C Disease Neutral P02458 G1176S Disease Disease P08123 G877C Disease Disease P02452 G1195C Disease Disease P08123 G754R Disease Neutral P02458 G375R Disease Neutral P02461 G786R Disease Neutral P02452 G224C Disease Disease P08123 G895D Disease Disease P02458 T1439M Disease Neutral P02461 G321V Disease Disease P02461 G417R Disease Neutral P02458 G1143S Disease Disease P08123 R822H Neutral Neutral P02461 G1161V Disease Disease P02458 G897V Disease Neutral P08123 G592S Disease Neutral P02452 G1100S Disease Disease P02461 G900D Disease Neutral P08123 G640S Disease Neutral P02452 G869C Disease Neutral P02452 G926C Disease Neutral P02452 W1312C Disease Disease P02458 T638I Neutral Neutral P08123 G1078C Disease Disease P02452 G527C Disease Neutral P02461 G303R Disease Disease P08123 G328S Disease Neutral P02452 G401C Disease Neutral P02458 G1197S Disease Disease P02452 G842R Disease Neutral P02458 G981S Disease Disease P02452 G719S Disease Neutral P02452 G1061D Disease Disease P02452 G1166C Disease Disease P02458 G447S Disease Neutral P02461 G1011E Disease Disease P02452 G356C Disease Neutral P02461 G879V Disease Neutral P02461 G267V Disease Disease P02461 G252R Disease Disease P02458 G909C Disease Neutral P02452 G815V Disease Neutral P02461 G1170V Disease Disease P02461 G297R Disease Disease P02458 G513S Disease Neutral P02452 G728R Disease Neutral P02452 G701C Disease Neutral P02452 G263R Disease Disease P02458 D1469H Disease Disease P02452 G353C Disease Neutral P08123 A276T Neutral Neutral P02452 G1010S Disease Disease P02458 G1017V Disease Disease P02458 G510D Disease Neutral P02458 R719C Disease Disease P08123 G634V Disease Neutral P02458 G1065V Disease Disease P02452 G845R Disease Neutral P08123 G409V Disease Neutral P08123 G547R Disease Neutral P02452 T1431P Neutral Disease P08123 A564T Neutral Neutral P02452 S1251T Neutral Neutral P02461 G552E Disease Neutral P02458 G771A Disease Neutral P02452 G275D Disease Disease P02461 G219C Disease Disease P02461 G567E Disease Neutral P02461 G1173R Disease Disease P02458 G267D Disease Disease P02458 E142D Neutral Neutral P02452 G1088A Disease Disease P02452 G656S Disease Neutral P08123 A549P Neutral Neutral P02461 G1050V Disease Disease P02458 T1390N Disease Disease P02461 G1032V Disease Disease P02452 G1022V Disease Disease P08123 G790D Disease Neutral P02461 G744V Disease Neutral P02452 G560R Disease Neutral P02458 G453D Disease Neutral P02458 G318R Disease Disease P02452 G737D Disease Neutral P02461 G1179R Disease Disease P02461 G249V Disease Disease P02461 G1170D Disease Disease P02452 T1434S Neutral Disease P02452 R1014C Disease Neutral P02458 P158L Neutral Neutral P02458 G504S Disease Neutral P02458 R989C Disease Neutral P02461 G1164E Disease Disease P08123 S1198P Neutral Disease P08123 I249N Neutral Neutral P02461 L169F Disease Neutral P08123 G1096A Disease Disease P02461 G183C Disease Disease P02452 L1388R Disease Disease P02461 G255V Disease Disease P02452 G197C Neutral Disease P02458 G774S Disease Neutral P02461 G828R Disease Neutral P02452 R564H Neutral Neutral P02452 G743S Disease Neutral P02452 Q1391K Neutral Neutral P02461 G909D Disease Neutral P08123 G751S Disease Neutral P02461 G636R Disease Neutral P02458 G1405S Neutral Neutral P02461 G1044D Disease Disease P02461 G1185D Disease Disease P02458 G969S Disease Disease P02452 G398D Disease Neutral P02461 G1176V Disease Disease P02461 G936R Disease Neutral P02461 G588D Disease Neutral P02452 G1184V Disease Disease P02461 G204D Disease Disease P02461 G1035C Disease Disease P02452 G839S Disease Neutral P08123 G331D Disease Neutral P02458 G453V Disease Neutral P02458 G855S Disease Neutral P02461 G243V Disease Disease P02458 G891R Disease Neutral P02461 G942E Disease Neutral P02461 G903E Disease Neutral P02452 G1124C Disease Disease P02458 G717S Disease Neutral P02452 G389R Disease Neutral P02452 G896C Disease Neutral P02461 G1089D Disease Disease P02452 G1076S Disease Disease P02461 G660D Disease Neutral P08123 G676V Disease Neutral Q86SQ0 P941S Neutral Neutral P49821 T423M Disease Disease P49821 I76V Neutral Neutral P49821 N277Y Neutral Neutral P49821 A341V Disease Disease Q2M3C7 G425R Neutral Neutral Q2M3C7 H847Q Neutral Neutral Q2M3C7 Q867R Neutral Neutral Q2M3C7 K617E Neutral Neutral Q9NR63 V479I Neutral Neutral Q9NR63 R191H Neutral Disease Q9NR63 A420G Neutral Neutral Q9NR63 V181M Neutral Neutral Q9NR63 E380K Neutral Disease Q9NR63 D227N Neutral Disease Q6V0L0 R245Q Neutral Neutral Q9NR63 A185V Neutral Disease Q9NR63 R473C Neutral Neutral Q9NR63 L264S Neutral Neutral P83111 R469K Neutral Neutral Q6ZUM4 Q889H Neutral Neutral Q9H0I3 D4E Neutral Neutral Q9H0I3 S6T Neutral Neutral Q8WU03 L168I Neutral Neutral Q8WU03 E160K Neutral Neutral Q6IB77 S156N Neutral Neutral Q6IB77 S17T Neutral Neutral Q8WU03 P82S Neutral Neutral Q96JA1 M615V Neutral Neutral Q96JA1 G926S Neutral Neutral Q96JA1 A957T Neutral Neutral Q96JA1 P1031R Neutral Neutral Q96JA1 Q1053P Neutral Neutral Q16543 G360E Neutral Neutral Q6NUJ5 R98G Neutral Neutral Q6NUJ5 R89C Neutral Neutral Q9H3S7 A944T Neutral Neutral Q9H3S7 P1099S Disease Neutral O43314 P1206Q Neutral Neutral O43314 R1003K Neutral Neutral O43314 T1232M Neutral Neutral O43314 E985K Neutral Neutral O43314 A944G Neutral Neutral A1L0T0 N374D Neutral Neutral P17302 R76S Disease Disease P17302 I130T Disease Neutral P17302 S27P Disease Disease P17302 G22E Disease Disease P17302 Y185H Neutral Disease P17302 A253V Neutral Neutral P17302 G143S Disease Disease P17302 R362Q Disease Neutral P17302 A40V Disease Disease P17302 Q49K Disease Disease P17302 Y98C Disease Disease P17302 L113P Disease Disease P17302 T204M Neutral Disease P17302 L90V Disease Disease P17302 R202H Disease Disease P17302 V216L Disease Disease P17302 I31M Disease Disease P17302 G21R Disease Disease P17302 T290N Neutral Neutral P17302 S18P Disease Disease P17302 A168T Neutral Neutral P17302 K102N Disease Disease P17302 D124E Neutral Neutral P17302 R148Q Neutral Disease P17302 R239W Neutral Disease P17302 S69Y Disease Disease P17302 Y17S Disease Disease P17302 K134N Disease Neutral P17302 R376Q Disease Neutral P17302 K134E Disease Neutral P17302 R202C Neutral Disease P17302 G138R Disease Neutral P17302 P283L Neutral Neutral P17302 K23T Disease Disease P16284 L125V Neutral Neutral P24592 R128G Neutral Neutral P24592 T236P Neutral Neutral P24592 R217L Neutral Disease P24592 R217Q Neutral Neutral P22692 V42G Neutral Neutral P24593 R138W Neutral Neutral Q8N9B4 N198D Neutral Neutral Q99102 G37D Neutral Neutral Q99102 S585A Neutral Neutral Q99102 T161A Neutral Neutral Q13011 E41A Neutral Neutral Q13011 G217R Neutral Disease P15428 Y217C Neutral Disease Q8N4T8 M70L Neutral Neutral Q99714 R130C Disease Disease Q99714 N247S Disease Disease Q99714 L122V Disease Neutral P35544 T53I Neutral Neutral Q06481 D632N Neutral Neutral P05067 T714I Disease Disease P05067 V717G Disease Disease P05067 A713T Disease Disease P05067 L705V Disease Disease P05067 L723P Disease Disease P05067 T714A Disease Disease P05067 E693G Disease Disease P05067 A713V Neutral Disease P05067 D694N Disease Disease P05067 V717F Disease Disease P05067 E501K Neutral Disease P05067 V717L Disease Disease P05067 E693K Disease Disease P05067 V717I Disease Neutral P05067 V715M Disease Neutral P05067 E665D Disease Neutral P05067 E693Q Disease Disease P05067 A692G Disease Neutral P05067 I716V Disease Disease P05060 A243T Neutral Neutral P05060 A353G Neutral Neutral P05060 N200H Neutral Neutral P05060 D145N Neutral Neutral P05060 R232Q Neutral Neutral P05060 K117N Neutral Neutral P05060 R417H Neutral Neutral P05060 R178Q Neutral Neutral P05060 P413L Neutral Neutral P08708 E36K Neutral Disease Q4VC05 N120T Neutral Neutral P40337 S65A Disease Neutral P40337 S65W Disease Neutral P40337 L118P Disease Disease P40337 E52K Disease Neutral P40337 W88S Disease Disease P40337 S68W Disease Neutral P40337 Y156D Disease Disease P40337 Q164R Disease Neutral P40337 P25L Disease Neutral P40337 D143E Disease Neutral P40337 L184P Disease Disease P40337 I147T Disease Neutral P40337 P81S Disease Neutral P40337 S80I Disease Neutral P40337 F119S Disease Disease P40337 L101G Disease Neutral P40337 S80R Disease Disease P40337 C162F Disease Disease P40337 N78T Disease Disease P40337 L188V Disease Neutral P40337 H191D Disease Neutral P40337 R167Q Disease Disease P40337 L118R Disease Disease P40337 N131K Disease Disease P40337 T157I Disease Disease P40337 R79P Disease Disease P40337 Y156N Disease Disease P40337 G93D Disease Disease P40337 Y112N Disease Neutral P40337 L188Q Disease Neutral P40337 L198Q Disease Neutral P40337 Q145H Disease Neutral P40337 Q96P Disease Neutral P40337 L101R Disease Disease P40337 L163P Disease Disease P40337 V155M Disease Neutral P40337 N78S Disease Neutral P40337 L158V Disease Neutral P40337 I180V Disease Neutral P40337 L128F Disease Neutral P40337 R161Q Disease Neutral P40337 S111N Disease Neutral P40337 T105P Disease Neutral P40337 H115Q Disease Neutral P40337 C162R Disease Disease P40337 L89H Disease Neutral P40337 V84L Disease Disease P40337 R64P Disease Neutral P40337 R167W Disease Disease P40337 L158P Disease Disease P40337 Y98H Disease Neutral P40337 G106D Disease Neutral P40337 P86R Disease Neutral P40337 N131T Disease Neutral P40337 E186K Disease Neutral P40337 Y156C Disease Disease P40337 S111C Disease Neutral P40337 G93C Disease Disease P40337 F136C Disease Disease P40337 A122I Disease Disease P40337 F119L Disease Disease P40337 V166D Disease Disease P40337 S65L Disease Neutral P40337 P192S Disease Neutral P40337 L116V Disease Neutral P40337 S80N Disease Neutral P40337 P86L Disease Disease P40337 R107G Disease Neutral P40337 P86A Disease Neutral P40337 C162W Disease Disease P40337 S38P Disease Neutral P40337 Y175D Disease Disease P40337 V170D Disease Disease P40337 L184R Disease Disease P40337 R82P Disease Disease P40337 E70K Disease Neutral P40337 R176W Disease Neutral P40337 L178P Disease Disease P40337 L188P Disease Disease P40337 G93S Disease Neutral P40337 F76L Disease Neutral P40337 P86S Disease Neutral P40337 F136S Disease Disease P40337 W117C Disease Disease P40337 V170F Disease Neutral P40337 Y112H Disease Neutral P40337 F76S Disease Disease P40337 F76I Disease Neutral P40337 V155G Disease Disease P40337 R161P Disease Disease P40337 V170G Disease Neutral P40337 G114R Disease Disease P40337 V166F Disease Neutral P40337 L178Q Disease Disease P40337 H115R Disease Neutral P40337 R167G Disease Neutral P40337 L89P Disease Disease P40337 P154L Disease Disease P40337 R161G Disease Neutral P40337 H115Y Disease Disease P40337 S111R Disease Neutral P40337 R200W Disease Neutral P40337 V130L Disease Neutral P40337 R107P Disease Disease P40337 C162Y Disease Disease P40337 P86H Disease Neutral P40337 G114C Disease Disease P40337 K159E Disease Neutral P40337 G114S Disease Neutral P40337 W88R Disease Disease P40337 D126Y Disease Disease P40337 L63P Disease Neutral P40337 D121G Disease Disease P40337 N78H Disease Neutral P40337 A149T Disease Neutral P40337 V74G Disease Neutral P40337 F136Y Disease Neutral P40337 Q164H Disease Neutral P40337 L198R Disease Disease Q6XYQ8 T420S Neutral Neutral Q6XYQ8 A505V Neutral Neutral Q6XYQ8 H488P Neutral Neutral O95299 A2G Neutral Neutral Q99062 Q346R Neutral Neutral Q99062 R583C Neutral Neutral Q99062 M231T Neutral Neutral Q99062 Y562H Neutral Disease Q99062 D510H Neutral Disease Q99062 E405K Neutral Neutral Q99062 R440Q Neutral Neutral Q99062 D320N Neutral Neutral O14924 I225V Neutral Neutral O14924 N1124S Neutral Neutral O14924 M277L Neutral Neutral Q9BUU2 W59S Neutral Neutral Q9BUU2 A219T Neutral Neutral Q8TBC4 K9R Neutral Neutral Q9BY12 P1088T Neutral Neutral Q9NQ48 D246N Neutral Neutral Q9NQ48 K152E Neutral Neutral Q9NQ48 Q251R Neutral Neutral Q86TU6 E21D Neutral Neutral O95977 R365L Neutral Neutral A4FU69 L237V Neutral Neutral A4FU69 K278I Neutral Neutral A4FU69 R561S Neutral Neutral Q9H3Y6 V457L Neutral Neutral Q9H3Y6 A453T Neutral Neutral Q9H3Y6 R73C Neutral Disease Q9H3Y6 S465T Neutral Neutral P42681 R336Q Neutral Disease Q9H3Y6 D377E Neutral Neutral Q9H3Y6 G75R Neutral Disease Q9H3Y6 V301L Neutral Disease Q9H3Y6 A397V Neutral Disease Q9H3Y6 P452L Neutral Disease P42681 R63C Neutral Neutral P42681 R45H Neutral Neutral Q9H3Y6 I88V Neutral Neutral A6NCF5 A516T Neutral Neutral A6NCF5 E345G Neutral Neutral A6NCF5 R176Q Neutral Neutral A6NCF5 R163H Neutral Disease P38484 Q64R Neutral Neutral P38484 T168N Disease Neutral P38484 K182E Neutral Neutral P38484 T58R Neutral Neutral P38484 E147K Neutral Neutral P37288 G6S Neutral Neutral Q6NXT6 E465K Neutral Neutral Q6NXT6 N522S Neutral Neutral P55809 T58M Neutral Disease P55809 V133E Disease Disease P55809 G219E Disease Disease P55809 G324E Disease Disease P55809 V221M Disease Disease P55809 C456F Disease Disease Q9Y4K0 M570L Neutral Neutral Q9NUQ7 N77T Neutral Neutral Q9GZQ4 M388V Neutral Neutral Q9GZQ4 P383L Neutral Neutral Q9GZQ4 T395A Neutral Neutral Q9GZQ4 F315L Neutral Disease Q9GZQ4 S298T Neutral Neutral O60216 G481R Neutral Neutral O00233 A17V Neutral Neutral P31040 A524V Disease Disease P31040 R554W Disease Disease P31040 G555E Disease Disease Q9Y653 Q306H Neutral Neutral Q9Y653 Y88C Disease Disease Q9Y653 C91S Disease Disease Q9Y653 R565W Disease Disease Q9Y653 S281R Neutral Neutral Q9Y653 C346S Disease Disease Q9Y653 R38W Disease Neutral Q9UJY4 A424P Neutral Neutral O00555 P2394S Neutral Neutral O00555 V714A Disease Disease O00555 R192Q Disease Disease O00555 T666M Disease Disease O00555 E918D Neutral Neutral O00555 P914S Neutral Neutral O00555 A21V Neutral Neutral O00555 E1015K Neutral Neutral O00555 G1105S Neutral Neutral O00555 I1810L Disease Disease Q13438 R398W Neutral Neutral Q13438 S454L Neutral Neutral Q9BUY7 T45A Neutral Neutral Q9BUY7 D31G Neutral Neutral Q9BUY7 A15V Neutral Neutral Q13555 S36P Neutral Disease Q9NQ86 N678D Neutral Neutral Q9NQ86 N456S Neutral Neutral Q9NQ86 K428R Neutral Neutral Q96IS3 G137R Disease Neutral Q96IS3 R87Q Disease Disease P49286 G24E Neutral Neutral P48039 R54W Neutral Disease P48039 A157V Neutral Neutral P49286 L66F Neutral Neutral P23276 S726A Neutral Neutral P78562 L138P Disease Disease P78562 G579V Disease Disease P78562 L160R Disease Disease P78562 Y317F Disease Neutral P78562 W530C Disease Disease P78562 Q621R Disease Disease P78562 N680K Disease Disease P23276 A163T Neutral Neutral P23276 L597P Neutral Disease P78562 R651P Disease Disease P78562 L555P Disease Disease P78562 C693Y Disease Disease P42892 T341I Neutral Neutral P78562 D237G Disease Neutral P78562 P534L Disease Disease P78562 C85Y Disease Disease P78562 C85F Disease Disease P23276 T193M Neutral Neutral P78562 R166C Disease Disease P78562 G579R Disease Disease P78562 M253I Disease Disease P78562 F252S Disease Disease P78562 W749R Disease Disease O95672 H10Q Neutral Neutral O95672 H328Y Neutral Neutral P78562 A573D Disease Disease P78562 C733S Disease Disease P78562 R567P Disease Disease P23276 R281W Neutral Disease P78562 C142F Disease Disease P78562 C746W Disease Disease P78562 F731Y Disease Disease P78562 C85R Disease Disease P78562 C77S Disease Disease P78562 F80S Disease Disease P78562 A720T Disease Neutral P78562 S141P Disease Disease Q495T6 M518T Neutral Neutral Q9NX65 Y120H Neutral Disease P18089 G211A Neutral Neutral P21917 V194G Neutral Neutral P18089 V379G Neutral Disease P21917 P329A Neutral Neutral P18089 V376I Neutral Neutral P21917 G332S Neutral Neutral P18089 V379I Neutral Neutral Q8NI22 D129E Disease Disease Q8NI22 I136T Disease Neutral Q8NHL6 L620F Neutral Neutral O75022 A574V Neutral Neutral O75022 Y405H Neutral Neutral O75022 Q59R Neutral Neutral O75022 R205Q Neutral Disease O75022 Y400H Neutral Neutral O75022 Y400F Neutral Neutral Q8NHL6 L68P Neutral Disease Q8NHL6 I142T Neutral Neutral O75022 V21M Neutral Neutral O75022 L69W Neutral Neutral O75022 Q90E Neutral Neutral O75022 H539Q Neutral Neutral O75022 S122N Neutral Neutral Q8NHL6 S155I Neutral Neutral Q14213 V201I Neutral Neutral O94985 V474A Neutral Neutral O94985 P583R Neutral Neutral O94985 F870S Neutral Disease O94985 P857H Neutral Disease O94985 S524C Neutral Neutral Q4G0U5 M509I Neutral Neutral Q4G0U5 I351V Neutral Neutral Q96BH3 D215N Neutral Disease Q96BH3 K199E Neutral Neutral Q96BH3 D170N Neutral Neutral Q96BH3 C100W Neutral Disease Q2I0M5 C107R Disease Disease Q2I0M5 Q65R Disease Disease Q2I0M5 C118Y Disease Disease Q2I0M5 C95F Disease Disease Q14353 T209M Neutral Neutral P03915 M314V Neutral Neutral P03915 G465E Disease Disease P03915 T331A Neutral Neutral P03915 E145G Disease Disease P03915 I257V Neutral Neutral P03915 S99P Neutral Disease P03915 A171V Disease Disease P03915 D393N Disease Disease P03915 F304S Neutral Disease P03915 A458T Disease Disease P03915 F124L Disease Neutral P03915 A475T Neutral Neutral P03915 F95S Neutral Neutral P03915 P17S Neutral Neutral P03915 A160V Neutral Disease P03915 N165S Neutral Disease P03915 T211P Neutral Neutral P03915 D503G Neutral Disease P03915 G146D Neutral Disease Q9UKS7 N93S Neutral Neutral Q9NYL2 Y773H Neutral Neutral Q9NYL2 A281V Neutral Neutral Q9NYL2 K784T Neutral Neutral Q9NYL2 L531S Neutral Neutral Q9NYL2 P740T Neutral Neutral Q9NYL2 T267M Neutral Neutral Q9NYL2 R580W Neutral Neutral Q8IV01 N170H Neutral Neutral P0C6C1 P427H Neutral Neutral P0C6C1 P369R Neutral Neutral P0C6C1 L442I Neutral Neutral A5PLL1 S156L Neutral Neutral Q9P2W1 Y163N Neutral Neutral Q9P1A6 T620M Neutral Neutral Q9P1A6 P419Q Neutral Neutral Q68CZ1 D1264N Neutral Neutral Q68CZ1 T615P Disease Neutral Q68CZ1 G1025S Neutral Neutral Q68CZ1 R744Q Neutral Neutral Q68CZ1 A695P Disease Disease Q14093 G208D Neutral Neutral Q14093 A319E Neutral Neutral Q14093 K190E Neutral Neutral Q15544 T68R Neutral Neutral P48444 K309N Neutral Neutral P48444 F186L Neutral Neutral Q00653 G351R Neutral Neutral Q00653 G452R Neutral Neutral Q00653 E14K Neutral Neutral O43173 K91T Neutral Neutral O43291 V200L Neutral Neutral P00156 I7T Neutral Neutral P00156 I334V Neutral Neutral P00156 N8S Neutral Disease P00156 F18L Neutral Neutral P00156 V353M Neutral Neutral P00156 A122T Neutral Neutral P00156 F276L Disease Neutral P00156 N260D Neutral Disease P00156 D171N Disease Disease P00156 A229T Neutral Neutral P00156 A39T Neutral Neutral P00156 I78T Neutral Disease P00156 I306T Neutral Neutral P00156 M316T Neutral Neutral P00156 V356M Disease Neutral P00156 A39V Neutral Neutral P00156 A329T Neutral Neutral P00156 T360A Neutral Neutral P00156 T368I Neutral Neutral P00156 T123A Neutral Neutral P00156 A87P Neutral Disease P00156 I78V Neutral Neutral P00156 A330T Neutral Neutral P00156 T194A Neutral Neutral P00156 I153T Neutral Disease P00156 A191T Neutral Neutral P00156 I164V Neutral Neutral P00156 G251D Disease Disease P00156 L236I Neutral Neutral P00156 R80H Disease Disease Q8IUR5 L706V Neutral Disease Q6UVW9 G136D Neutral Neutral Q13702 N88K Disease Disease Q13702 L14P Disease Neutral Q08431 R3S Neutral Neutral Q08431 M76L Neutral Neutral P19878 A128V Disease Disease P19878 R328K Neutral Neutral P19878 T279M Neutral Neutral P19878 R395W Disease Neutral P19878 K181R Neutral Neutral P19878 G78E Disease Disease P19878 V297A Neutral Neutral P19878 R77Q Disease Disease Q7Z410 S30T Neutral Neutral Q7Z410 R73W Neutral Neutral Q7Z410 S793N Neutral Neutral Q7Z410 E938K Neutral Neutral Q6H9L7 A94T Neutral Neutral Q6H9L7 P133A Neutral Neutral Q96QH2 Q73P Neutral Neutral Q96QH2 F76V Neutral Neutral Q96QH2 Q57K Neutral Neutral Q9Y5N6 P138Q Neutral Disease Q9Y5N6 R32W Neutral Neutral Q8ND56 R448Q Neutral Neutral O00628 T14P Disease Disease O00628 G217R Disease Disease O00628 A218V Disease Neutral Q6ZU80 H732R Neutral Neutral Q6ZU80 R16L Neutral Neutral Q9UNX4 P234A Neutral Neutral P12643 S37A Neutral Neutral P34820 H293R Neutral Neutral P12643 A106T Neutral Disease P12643 R190S Neutral Disease P12644 V152A Neutral Neutral Q9H5L6 M284I Neutral Neutral Q9H5L6 N812D Neutral Neutral Q9H5L6 L299F Neutral Neutral Q9H0Z9 A155V Neutral Neutral Q9H0Z9 A177D Neutral Disease Q9H0Z9 P189H Neutral Neutral Q8N9M5 A110V Neutral Neutral Q99856 K320E Neutral Disease Q99856 G556S Neutral Neutral Q99856 P36H Neutral Neutral Q8IXR5 R793C Neutral Neutral P18428 V166M Neutral Neutral P18428 A445T Neutral Neutral P18428 P333L Neutral Disease P18428 F436L Neutral Neutral P18428 L125I Neutral Neutral P17213 A196V Neutral Neutral P18428 P9L Neutral Neutral P18428 M242I Neutral Neutral P18428 D283G Neutral Disease P18428 L339F Neutral Disease P18428 H294R Neutral Neutral P17213 V16A Neutral Neutral P17213 K216E Neutral Neutral Q9H9J2 T138I Neutral Neutral Q5MJ08 K48N Neutral Neutral Q96M02 D262N Neutral Neutral Q96M02 R134H Neutral Neutral P30711 D141N Neutral Neutral P30711 V169I Neutral Neutral P30712 M139I Neutral Neutral P30711 A21T Neutral Disease P30711 E173K Neutral Disease P30712 E129K Neutral Neutral Q8WTR4 A480T Neutral Neutral Q9Y253 T478M Neutral Neutral Q9Y253 G263V Disease Disease Q9Y253 K589T Disease Neutral Q9Y253 R334W Neutral Neutral Q9Y253 R111H Disease Disease Q9Y253 K535E Disease Neutral Q9Y253 M647L Neutral Neutral Q9Y253 L584P Neutral Neutral Q9Y253 R361S Disease Disease Q9Y253 G209V Neutral Disease Q9Y253 T122P Disease Disease Q9Y253 M595V Neutral Neutral Q3KQV9 A319V Neutral Neutral Q16222 P418H Neutral Disease Q3KQV9 P373S Neutral Disease P50052 C268W Neutral Neutral P50052 R248K Neutral Neutral Q9H0U6 R6Q Neutral Neutral Q17RW2 G1423R Neutral Disease Q7LG56 V115L Disease Disease Q14678 S464A Neutral Neutral Q14678 E432Q Neutral Neutral Q14678 N206K Neutral Neutral Q9Y6V7 S296A Neutral Neutral Q9Y6V7 R222H Neutral Neutral P17022 Q210R Neutral Neutral P17022 M240I Neutral Disease O76075 R196K Neutral Neutral P00403 V142M Disease Neutral P00403 I30V Neutral Neutral P00403 L123P Neutral Disease P00403 A148T Neutral Neutral P00403 M29K Disease Disease P00403 D11A Neutral Disease P00403 T187M Neutral Disease Q92793 H1470R Disease Disease Q09472 P2223Q Neutral Neutral Q92793 R1664H Disease Neutral Q09472 E1013G Disease Neutral Q92793 R1378P Disease Disease Q09472 S1650Y Disease Disease Q09472 P2221Q Disease Neutral Q09472 L827P Disease Neutral Q92793 E1278K Disease Disease Q92793 T1447I Disease Disease Q92793 V1414I Neutral Neutral Q09472 T2174S Neutral Neutral Q92793 Y1175C Disease Disease Q92793 Y1450H Disease Disease Q09472 I997V Neutral Neutral Q99816 M167I Neutral Neutral Q6UWE0 N318D Neutral Neutral Q9BYG8 P23S Neutral Neutral Q9BYG8 R150K Neutral Neutral Q9BYG8 T475M Neutral Neutral Q9NXZ1 L805S Neutral Neutral Q9NXZ1 N741K Neutral Neutral O94854 E1058K Neutral Neutral O94854 I824V Neutral Neutral O94854 T969A Neutral Neutral Q9BS91 N247I Neutral Disease O00499 D151N Disease Disease O00499 K35N Disease Disease P78330 D32N Disease Disease P78330 M52T Disease Disease P60484 P246L Disease Neutral P60484 G132V Disease Disease P60484 T167P Disease Disease P60484 G165V Disease Disease P60484 S170R Disease Disease P60484 R47G Disease Disease P60484 I135V Disease Neutral P60484 I67R Disease Disease P60484 K342N Disease Disease P60484 L345Q Disease Disease P60484 R234Q Disease Neutral P60484 K289E Disease Neutral P60484 H93R Disease Disease P60484 H123Y Disease Disease P60484 G165E Disease Disease P60484 H123R Disease Disease P60484 V119L Disease Disease P60484 C136Y Disease Disease P60484 A121G Disease Disease P60484 D331G Disease Disease P60484 Y68H Disease Neutral P60484 C105F Disease Disease P60484 V290L Neutral Neutral P60484 L57W Disease Disease P60484 D107Y Disease Neutral P60484 G36E Disease Disease P60484 R15S Disease Disease P60484 G129R Disease Disease P60484 L70P Disease Disease P60484 F347L Disease Disease P60484 R130Q Disease Disease P60484 C105Y Disease Disease P60484 G129E Disease Disease P60484 A34D Disease Disease P60484 C124S Disease Disease P60484 L42R Disease Neutral P60484 D19N Disease Neutral P60484 V158L Disease Neutral P60484 H93Y Disease Disease P60484 V217I Disease Neutral P60484 M134L Disease Neutral P60484 F341V Disease Disease P60484 D252G Disease Disease P60484 C124R Disease Disease P60484 A121P Disease Disease P60484 L112P Disease Disease P60484 R130L Disease Disease P60484 F241S Disease Disease P60484 C71Y Disease Disease P60484 G165R Disease Disease P60484 Y155C Disease Disease P60484 M35R Disease Disease P60484 V343E Disease Disease Q8TCS8 I121V Neutral Neutral Q8TCS8 N590D Neutral Neutral P31641 L18V Neutral Neutral P23975 I549T Neutral Neutral P31645 L550V Neutral Neutral P31645 F465L Neutral Neutral P23975 G478S Neutral Neutral P23975 V356L Neutral Disease P31641 W236C Neutral Disease P23975 T283R Neutral Disease P23975 V449I Neutral Neutral P23975 V245I Neutral Neutral P31645 K605N Neutral Neutral P23975 T99I Neutral Disease P23975 N292T Neutral Neutral P23975 N375S Neutral Neutral P31645 G56A Neutral Neutral P23975 F528C Neutral Disease P23975 A369P Neutral Disease P23975 V69I Neutral Neutral P23975 Y548H Neutral Disease P23975 K463R Neutral Neutral P31641 I17M Neutral Neutral P31645 K201N Neutral Neutral P23975 N7K Neutral Neutral P31645 I425V Neutral Neutral P31645 I425L Neutral Disease P48029 T164S Neutral Neutral P23975 A457P Disease Disease Q8WXG9 G2379A Neutral Neutral Q8WXG9 S2764L Neutral Disease Q8WXG9 A3217V Neutral Neutral Q8WXG9 P1987L Neutral Neutral Q8WXG9 V1951I Neutral Neutral Q8WXG9 N2584S Neutral Neutral Q8WXG9 E3471K Neutral Neutral Q8WXG9 R249K Neutral Neutral Q8WXG9 L1093F Neutral Neutral Q8WXG9 G3248D Neutral Neutral Q8WXG9 L127R Neutral Disease Q8WXG9 N1985D Neutral Neutral Q8WXG9 L2004F Neutral Neutral Q8WXG9 N2345S Neutral Disease Q8WXG9 A2803T Neutral Neutral Q8WXG9 T1927M Neutral Neutral Q8WXG9 Y2232C Neutral Disease Q8WXG9 E5344G Neutral Neutral Q8WXG9 T5438A Neutral Neutral Q8TBG4 S185P Neutral Neutral P14867 A322D Disease Disease O15230 A1434G Neutral Neutral O15230 R2226H Neutral Neutral O15230 D2062N Neutral Disease O15230 H1717Y Neutral Neutral O15230 F1807S Neutral Neutral O15230 R1667W Neutral Neutral O15230 K1367E Neutral Neutral O15230 A1908T Neutral Neutral O15230 W3079R Neutral Neutral O15230 H2036R Neutral Neutral O15230 V889M Neutral Neutral O15230 R2053H Neutral Disease O15230 T1258M Neutral Neutral O15230 M1900V Neutral Neutral P98172 V189A Neutral Neutral P98172 P54L Disease Disease P98172 P119H Disease Disease P98172 T111I Disease Disease Q15768 R166Q Neutral Neutral P98172 S138F Disease Disease P98172 P119T Disease Disease P98172 S182R Disease Neutral P98172 G151V Disease Disease P98172 L98S Disease Disease P98172 I62T Disease Disease P98172 G151S Disease Disease P98172 C153S Disease Disease P98172 M158V Disease Neutral P98172 M158I Disease Disease P98172 T155P Disease Disease P98172 R154H Neutral Neutral P98172 P27R Disease Neutral P98172 P119S Disease Disease P98172 Q115P Disease Disease P98172 T137A Disease Disease P98172 C153Y Disease Disease Q9NP92 C33F Neutral Neutral Q9NP92 C33S Neutral Neutral Q32P41 E294A Neutral Neutral Q32P41 L255P Neutral Disease Q32P41 S217P Neutral Neutral P49069 V78I Neutral Neutral Q6UWY5 V113E Neutral Neutral Q6UWY5 A259T Neutral Neutral Q8N434 F385C Neutral Disease Q15848 G84R Neutral Disease Q15848 Y111H Neutral Neutral Q15848 V117M Neutral Disease Q15848 G90S Neutral Disease Q15848 H241P Neutral Neutral Q15848 I164T Neutral Disease Q15848 R221S Neutral Neutral Q15848 R112C Disease Disease Q8N655 P401A Neutral Neutral Q8N655 I535L Neutral Neutral Q8N655 N49S Neutral Neutral Q8N655 L314P Neutral Neutral P30307 G297R Neutral Disease P30307 R70C Neutral Neutral P30307 S78N Neutral Neutral P30307 S14N Neutral Neutral Q9NVH2 H425R Neutral Neutral Q9H0W7 T170M Neutral Neutral O60344 R571Q Neutral Neutral Q6GYQ0 T931A Neutral Neutral O75462 L374R Disease Disease O75462 W76G Disease Disease O75462 R81H Disease Neutral O75462 R176K Neutral Neutral Q13045 R1243H Neutral Disease O43181 T174P Neutral Neutral Q96LC7 A226V Neutral Neutral Q96LC7 R520S Neutral Neutral Q9UBV2 D162G Neutral Disease Q9BX84 S141L Disease Disease P51532 V561E Neutral Disease P51532 M1036I Neutral Neutral Q9UMR5 C5W Neutral Neutral Q9UMR5 A34E Neutral Disease Q9BUP3 G134V Disease Disease Q9BUP3 L144I Disease Neutral Q9BUP3 R197S Neutral Neutral Q9BUP3 D108Y Disease Disease Q9BUP3 R106S Disease Disease Q9BUP3 A116T Disease Disease Q68DE3 A1963V Neutral Neutral Q68DE3 A222P Neutral Neutral O43933 G843D Disease Disease O43933 L664P Disease Disease O43933 I696M Neutral Neutral P23743 H538Y Neutral Disease O95528 G142V Disease Disease O95528 T518A Neutral Neutral O95528 G246E Disease Disease O95528 E437K Disease Disease O95528 G445E Disease Disease O95528 R225H Neutral Disease O95528 S81R Disease Disease O95528 A106S Neutral Neutral O95528 R132W Disease Disease O95528 I537V Neutral Neutral O95528 R231Q Disease Disease O95528 A206T Neutral Neutral O95528 G426W Disease Disease Q96CN9 R86W Neutral Neutral Q96CN9 C87W Neutral Neutral P48551 F8S Neutral Neutral P48551 I196V Neutral Neutral P48551 F10V Neutral Neutral Q9NQW1 S527R Neutral Neutral O94979 P1055T Neutral Neutral Q9NQW1 V89A Neutral Neutral Q9NQW1 P372S Neutral Neutral Q9NQW1 Y100C Neutral Disease Q9NQW1 S332A Neutral Disease O94979 I263V Neutral Neutral Q9NQW1 A1169S Neutral Neutral O94979 P841L Neutral Neutral Q9NQW1 L129F Neutral Neutral P42771 E88D Disease Neutral P42771 E33D Disease Neutral P42771 G89S Disease Disease P42771 G122S Disease Disease P42771 N71K Disease Disease P42771 G89D Disease Disease P42771 N71S Neutral Disease P42771 R24C Disease Neutral P42771 R87P Disease Disease P42771 D84N Disease Disease P42771 H83Y Disease Disease P42771 A68L Disease Disease P42771 P81L Disease Neutral P42771 D84H Disease Disease P42771 G122R Disease Disease P42771 D108H Disease Disease P42771 E69K Disease Neutral P42771 R124H Disease Neutral P42771 G150V Disease Neutral P42771 L16P Disease Disease P42771 A68V Neutral Neutral P42771 A60T Neutral Disease P42771 L117M Disease Neutral P42771 H98P Disease Disease P42771 E120K Disease Neutral P42771 A127S Disease Neutral P42771 M53I Disease Disease P42771 A20S Disease Neutral P42771 A85T Neutral Disease P42771 R99P Disease Disease P42771 D74N Disease Disease P42771 E119Q Disease Neutral P42771 G101W Disease Disease P42771 H66Y Disease Neutral P42771 T93A Disease Disease P42771 A132P Disease Disease P42771 A20P Disease Disease P42771 A148T Neutral Neutral P42771 R24P Disease Disease P42771 A57V Disease Neutral P42771 L32P Disease Disease P42771 A102E Disease Disease P42771 V95A Disease Neutral P42771 Q50R Disease Disease P42771 R107C Disease Neutral P42771 R107H Neutral Neutral P42771 D108Y Disease Disease P42771 H83N Disease Disease P42771 L62P Disease Disease P42771 R80L Disease Disease P42771 R87W Disease Disease P42771 S56I Neutral Neutral P42771 H98Q Disease Neutral P42771 R99Q Disease Neutral P42771 A100P Neutral Disease P42771 A68T Disease Disease P42771 D14E Disease Neutral P42771 V59G Disease Disease P42771 G23D Disease Disease P42771 D84E Disease Disease P42771 H123Q Disease Disease P42771 D74V Disease Disease P42771 P114L Disease Disease P42771 G35A Disease Neutral P42771 E120A Disease Neutral P42771 L94Q Disease Disease P42771 A100L Disease Disease P42771 E69V Disease Neutral P42771 H142Y Disease Neutral P42771 R144C Disease Neutral P42771 L97R Neutral Disease P42771 D84Y Disease Disease P42771 A118T Disease Disease P42771 I49S Disease Disease P42771 E26D Disease Neutral P42771 A134V Disease Neutral P42771 I49T Neutral Disease P42771 V126D Disease Disease P42771 P48L Disease Neutral P42771 G35E Disease Disease P42771 C72G Disease Disease Q5T3J3 S599P Neutral Neutral Q5T3J3 I641M Neutral Neutral Q99217 W4S Disease Disease Q99217 P56T Disease Disease Q99217 T37I Disease Disease Q9BUV0 Y147H Neutral Neutral Q9BUV0 E239G Neutral Neutral Q9BZE9 V318M Neutral Neutral Q9BZE9 L252Q Neutral Neutral Q9BZE9 D487E Neutral Neutral Q15256 K314R Neutral Neutral P11086 R254H Neutral Neutral P11086 L217Q Neutral Disease P11086 T98A Neutral Neutral P11086 S188C Neutral Neutral P11086 W276R Neutral Neutral P11086 N9S Neutral Neutral P11086 R112C Neutral Neutral P11086 A175T Neutral Neutral P11086 L211H Neutral Disease P12757 V38A Neutral Neutral Q9BXL7 S694L Neutral Neutral Q9BXL7 T670M Neutral Neutral Q13563 W414G Disease Disease Q13563 A356P Disease Disease Q13563 R28P Neutral Neutral Q13563 I452V Neutral Neutral Q68CL5 R47C Neutral Disease Q6P3X3 R525H Neutral Neutral Q6P3X3 Y476C Neutral Disease P23142 R141Q Neutral Neutral P23142 R695H Neutral Neutral Q7L0X2 G433R Neutral Neutral Q7L0X2 G9V Neutral Neutral Q9H8E8 P214L Neutral Neutral Q9H8E8 G400V Neutral Neutral Q9H8E8 P600R Neutral Disease Q9H8E8 R442T Neutral Neutral Q9H9A7 S455N Neutral Neutral Q9H9A7 Y100H Neutral Neutral Q9UBC7 I72M Neutral Neutral Q8TEB9 A110T Neutral Neutral P11597 A390P Neutral Disease P11597 A15G Neutral Neutral P11597 V422I Neutral Neutral P11597 V385M Neutral Neutral P11597 R299C Disease Neutral P11597 V486M Neutral Neutral P11597 D459G Disease Neutral P11597 G331S Neutral Neutral P11597 R468Q Neutral Neutral P11597 R154W Neutral Neutral P11597 L168P Disease Disease P11597 V455M Neutral Neutral Q9NX52 L273M Neutral Neutral Q2M1K9 N629S Neutral Neutral Q96N96 R20W Neutral Neutral Q03169 Q282E Neutral Neutral Q03169 T565I Neutral Neutral Q03169 T580M Neutral Neutral P30043 R46Q Neutral Neutral P51172 C532Y Neutral Neutral P51172 E380Q Neutral Neutral P51172 R180P Neutral Disease P51172 G606R Neutral Neutral P51172 A472T Neutral Neutral P51172 G562S Neutral Neutral A6NGR9 T134I Neutral Neutral A6NGR9 H97Q Neutral Neutral A6NGR9 V132A Neutral Neutral O60260 G328E Disease Neutral O60260 G284R Disease Disease O60260 D394N Neutral Neutral O60260 T240R Disease Neutral O60260 R33Q Disease Neutral O60260 R256C Disease Neutral O60260 P37L Disease Neutral O60260 C212Y Disease Disease O60260 V380L Neutral Neutral O60260 D280N Disease Neutral O60260 S167N Neutral Neutral O60260 T351P Disease Neutral O60260 V15M Disease Neutral O60260 C289G Disease Disease O60260 P437L Disease Neutral O60260 R271S Neutral Neutral O60260 C441R Disease Disease O60260 C431F Disease Disease O60260 A82E Disease Neutral O60260 A46P Disease Disease O60260 C253Y Disease Disease O60260 Q100H Neutral Neutral O60260 T415N Disease Neutral O60260 K211R Disease Neutral O60260 R42P Disease Disease O60260 A339S Neutral Neutral O60260 M192V Disease Neutral O60260 R275W Disease Disease O60260 K211N Disease Disease O60260 T240M Disease Neutral O60260 R366W Neutral Disease O60260 R334C Disease Neutral O60260 G430D Disease Disease O60260 A92V Disease Neutral O60260 K161N Disease Neutral Q06250 A13T Neutral Neutral Q06250 G66A Neutral Neutral Q6RUI8 G104E Neutral Neutral Q6RUI8 V7I Neutral Neutral Q6RUI8 R84C Neutral Neutral Q8N130 A413E Disease Disease Q8N130 G337S Neutral Neutral Q8N130 R353L Disease Disease Q8N130 S138F Disease Disease Q8N130 D237N Neutral Neutral Q8N130 G196R Disease Disease Q8N130 R468W Disease Disease Q8N130 V513E Neutral Disease Q8N130 S192L Disease Disease Q8N130 G180A Neutral Neutral Q8N130 R67H Neutral Neutral Q8NI36 R529Q Disease Disease Q8NI36 A449T Disease Disease Q8NI36 N355S Disease Disease Q8NI36 I264V Neutral Neutral Q8NI36 M671V Neutral Disease Q8NI36 D658G Disease Disease Q7L014 E207Q Neutral Neutral P32780 S285F Neutral Neutral P32780 L517V Neutral Neutral P32780 R234W Neutral Disease Q9BXJ8 Q86R Neutral Neutral Q9BXJ8 T201A Neutral Disease P27352 Q23R Disease Neutral P20061 D301Y Neutral Disease P20061 R35H Neutral Neutral P27352 N255S Neutral Neutral P27352 S46L Disease Neutral Q9GZT9 P317R Disease Disease Q15835 P391H Disease Disease P32298 A142V Neutral Neutral Q15835 V380D Disease Disease P32298 R65L Neutral Neutral P32298 L425P Neutral Disease P32298 V247I Neutral Neutral P32298 V486A Neutral Neutral Q7Z429 S107N Neutral Neutral P29353 A205V Neutral Neutral Q8TAY4 Q69H Neutral Neutral Q92585 S1007N Neutral Neutral P02675 K2E Neutral Neutral P02675 P100S Neutral Neutral P02675 G430D Disease Disease P02675 L383R Disease Disease P02675 R196C Disease Disease P02675 N170H Neutral Neutral P02675 R478K Neutral Neutral P02675 P265L Neutral Disease Q6UWN8 P36T Neutral Neutral P06401 M301R Neutral Disease P06401 R625I Neutral Disease P06401 Q536P Neutral Disease P06401 S865L Neutral Neutral P06401 S344T Neutral Neutral P06401 L651V Neutral Neutral P06401 V529L Neutral Neutral P06401 A444S Neutral Neutral P06401 A120V Neutral Neutral P06401 C347S Neutral Neutral P06401 P186L Neutral Neutral P06401 V660L Neutral Neutral P06401 A50T Neutral Neutral Q96LL9 G34R Neutral Neutral Q86UK7 S453Y Neutral Neutral Q86UK7 C725S Neutral Neutral Q9NQV6 T487A Neutral Neutral Q02252 G446R Disease Disease Q96RI8 C291Y Neutral Disease Q96RI8 V265I Neutral Neutral Q96RI8 Y173C Neutral Disease Q96RI8 I37T Neutral Neutral Q96RI8 G165S Neutral Disease Q96RI8 A228V Neutral Neutral Q96RI8 V326I Neutral Neutral P30533 V311M Neutral Neutral Q7Z5N4 D1016N Neutral Disease Q7Z5N4 H1641R Neutral Disease Q8N1D0 R133G Neutral Neutral Q14978 S456P Neutral Neutral Q14978 G412V Neutral Neutral Q16665 T796A Neutral Disease Q9H0E7 A91T Neutral Neutral P78345 A114V Neutral Neutral P78345 A181G Neutral Neutral P78345 I212T Neutral Neutral P78345 E88D Neutral Neutral P27930 E181K Neutral Neutral P27930 E292K Neutral Disease P01031 T389I Neutral Neutral P01031 E1437D Neutral Neutral P01031 R449G Neutral Neutral P01031 F518S Neutral Neutral P01031 Q1043K Neutral Neutral P01031 R928Q Neutral Neutral P01031 S1310N Neutral Neutral P01031 D1037N Neutral Neutral P01031 V802I Neutral Neutral P01031 G933V Neutral Disease P01031 I1033T Neutral Neutral P01031 M1053L Neutral Neutral P01031 V145I Neutral Neutral Q9UGP4 G415R Neutral Neutral A5YKK6 D603A Neutral Neutral Q6ICL3 D245E Neutral Neutral Q6ICL3 E200K Neutral Neutral Q6ICL3 D125N Neutral Disease P30519 R137Q Neutral Disease P30519 P146L Neutral Disease Q8TDI7 S573C Neutral Neutral Q8TDI7 K123R Neutral Neutral Q8TDI7 E800Q Neutral Neutral P40937 A13T Neutral Neutral Q8N1F7 S509R Neutral Neutral Q8N1F8 R410G Neutral Neutral Q8N1F8 V563I Neutral Neutral Q8N1F8 I1085V Neutral Neutral Q8N1F8 R393H Neutral Neutral Q8N1F8 F752S Neutral Neutral Q14914 A27S Neutral Neutral Q9H0C1 L316F Neutral Neutral Q2M1V0 R83Q Neutral Disease Q2M1V0 A158V Neutral Neutral Q2M1V0 S28G Neutral Neutral Q2M1V0 P57S Neutral Neutral Q495N2 P185S Neutral Neutral Q6YBV0 P376H Neutral Disease Q6YBV0 L209I Neutral Neutral Q6YBV0 L429I Neutral Neutral Q495M3 A445V Neutral Neutral Q495N2 R190H Neutral Disease Q495N2 E415D Neutral Neutral Q495N2 K167E Neutral Neutral Q495N2 S421F Neutral Neutral Q96IZ5 H376Y Neutral Neutral Q53EZ4 L378H Neutral Neutral Q53EZ4 A99T Neutral Neutral Q53EZ4 H57Q Neutral Neutral P27918 Y414D Disease Disease P27918 G298V Disease Disease P27918 R100W Disease Disease P27918 Q343R Disease Neutral P12277 K177R Neutral Neutral P06732 L127V Neutral Neutral P06732 E83G Neutral Disease P12277 S309L Neutral Neutral P06732 G243A Neutral Disease O95988 G93R Neutral Neutral Q8WXJ9 S2N Neutral Neutral Q8IYT2 F753L Neutral Neutral Q8IYT2 T608K Neutral Neutral Q8IYT2 L60F Neutral Neutral Q8IYT2 N416S Neutral Neutral Q8IYT2 Y163F Neutral Neutral Q9UF33 F703S Neutral Neutral P00750 R164W Neutral Disease P00750 R136S Neutral Disease P00750 A34D Neutral Disease P00750 A146T Neutral Neutral Q96G91 A87T Neutral Neutral Q9BV94 A456T Neutral Neutral Q8N4C9 S152T Neutral Neutral Q8WUP2 S191F Neutral Neutral Q9ULV5 I87V Disease Neutral Q9ULV5 A20D Disease Disease Q8WXH2 I376T Neutral Disease Q8WXH2 P472T Neutral Neutral Q8WXH2 P645L Neutral Neutral Q8TDM6 P1481Q Neutral Neutral Q8TDM6 A1600V Neutral Disease Q8TDM6 Q140R Neutral Neutral Q687X5 G75D Neutral Neutral Q687X5 A122T Neutral Disease Q3ZCV2 G126C Neutral Disease P16070 T479I Neutral Neutral P16070 R417K Neutral Neutral P16070 D494H Neutral Disease P16070 T393M Neutral Neutral Q6ZMJ2 D316H Neutral Neutral Q5THJ4 A225T Neutral Neutral Q5THJ4 S1341L Neutral Neutral Q5THJ4 E1505V Neutral Neutral Q5THJ4 S1707F Neutral Disease Q92781 V177G Disease Disease Q92781 R280H Disease Disease Q92781 V132M Disease Neutral Q92781 G238W Disease Disease Q92781 G107R Disease Disease Q92781 S73F Disease Disease Q92781 G35S Disease Disease Q92781 A294P Disease Disease Q92781 V164F Disease Disease Q92781 Y281H Disease Disease Q92781 I33V Neutral Neutral Q92781 C267W Disease Disease P19075 G73A Neutral Disease A1L157 V190A Neutral Neutral P41732 E53K Neutral Disease P48509 P137S Neutral Neutral P41732 A127T Neutral Neutral P19075 S213A Neutral Neutral O60635 V87M Neutral Neutral P48509 R178H Neutral Neutral O43657 A108T Neutral Disease P48509 K132R Neutral Neutral P48509 T120M Neutral Neutral P41732 P172H Disease Neutral Q92629 E262K Disease Disease Q13326 G69R Disease Disease Q13326 S287N Neutral Neutral Q13326 G69D Disease Disease Q13326 R116H Neutral Disease Q92629 S151A Disease Neutral Q92629 Q97R Neutral Neutral Q13326 C283Y Disease Disease P19388 S44F Neutral Neutral Q13155 A129G Neutral Neutral Q15413 C693Y Neutral Neutral Q15413 V731I Neutral Neutral Q15413 S261R Neutral Neutral Q15413 I494V Neutral Neutral Q15413 E1380G Neutral Neutral O94788 E50G Neutral Neutral O94788 V348I Neutral Neutral P47895 M386V Neutral Neutral P30837 M253V Neutral Neutral P49419 K411Q Neutral Disease P49419 A171V Disease Disease P30837 A86V Neutral Disease P05091 E496K Neutral Disease P30837 T202I Neutral Disease O94788 A110V Neutral Disease P05091 E504K Neutral Disease P49419 T384A Neutral Disease O94788 E436K Neutral Disease Q9H2A2 F402S Neutral Disease P49419 E399Q Disease Neutral P49189 C116S Neutral Disease P30837 L107R Neutral Neutral P05091 E337V Neutral Neutral P00352 I177F Neutral Neutral Q8NEX5 N27T Neutral Neutral O75398 R530L Disease Disease O75398 R218K Disease Neutral O75398 T526N Disease Neutral O75398 E202D Disease Neutral O75398 E498K Disease Neutral O75398 K191N Disease Neutral O75398 E356H Disease Neutral O75398 Y397F Disease Neutral O75398 K191I Disease Disease O75398 E186V Disease Neutral O75398 Q367H Disease Neutral O75398 V370L Disease Neutral O75398 Q542H Disease Neutral O75398 S364N Disease Neutral O75398 E449K Disease Neutral O75398 A545V Disease Neutral O75398 Q468H Disease Neutral O75398 V442A Disease Neutral O75398 A545G Disease Neutral O75398 H479L Disease Neutral Q6GPH4 R132H Neutral Neutral Q6GPH4 R219I Neutral Neutral Q6GPH4 E188K Neutral Neutral Q6GPH4 E85G Neutral Neutral Q9NZR4 R166W Disease Disease Q9NZR4 H244R Disease Disease Q9NZR4 L159M Disease Neutral Q9NZR4 D144E Disease Neutral Q9NZR4 G160D Disease Neutral P58304 R227W Disease Disease P15848 L236P Disease Neutral P15848 W146S Disease Disease P15848 S65F Disease Disease P15848 W146R Disease Disease P15848 C521Y Disease Disease P15848 C405Y Disease Neutral P15848 F399L Disease Neutral P15848 P531R Disease Disease P15848 R484G Disease Neutral P15848 P116H Disease Disease P15848 M142I Disease Neutral P15848 W146L Disease Disease P15848 G302R Disease Disease P15848 L321P Disease Disease P15848 H393P Disease Disease P15848 T92M Disease Neutral P15848 G137V Disease Disease P15848 R160Q Disease Disease P15848 C192R Disease Disease P15848 S384N Disease Neutral P15848 V358M Neutral Disease P15848 G144R Disease Disease P15848 V376M Neutral Disease P15848 C117R Disease Neutral P15848 R315Q Disease Disease P15848 W312C Disease Neutral P15848 Q239R Disease Neutral P15848 L498P Disease Disease P15848 R95Q Disease Disease P15848 Y210C Disease Disease P15848 R152W Disease Disease P28222 E374K Neutral Disease P28566 S262F Neutral Disease P28222 I367V Neutral Neutral P28566 A208T Neutral Neutral P28222 F124C Neutral Neutral P28222 F219L Neutral Neutral P28221 S265L Neutral Disease O75496 N15H Neutral Neutral O75496 R54W Neutral Neutral O75496 L48F Neutral Neutral O75496 N18T Neutral Neutral Q9Y3A6 T175I Neutral Disease Q9H607 A109G Neutral Neutral Q9H607 R42L Neutral Neutral P26367 V126D Disease Disease P26367 R125C Disease Disease P26367 S43P Disease Disease P26367 R208Q Disease Disease P26367 F258S Disease Disease P26367 N17S Disease Disease P26367 A79E Disease Disease P26367 S292I Disease Neutral P26367 Q422R Disease Neutral P26367 G18W Disease Disease P26367 A33P Disease Disease P26367 I42S Disease Disease P26367 R208W Disease Disease P26367 S353A Disease Neutral P26367 R26G Disease Disease P26367 I29S Disease Disease P26367 V53L Disease Disease P26367 R44Q Disease Disease P26367 T63P Disease Disease P26367 G64V Disease Disease P26367 I29V Disease Neutral P26367 P375Q Disease Disease P26367 Q178H Disease Neutral P26367 R128C Disease Disease P26367 I87R Disease Disease P26367 S119R Disease Disease P26367 S363P Disease Disease P26367 V53D Disease Disease P26367 M381V Disease Neutral Q9NZD1 A18D Neutral Neutral Q8NFJ5 S118G Neutral Neutral Q9H902 A20E Disease Disease Q9UBU3 Q90L Neutral Neutral P23471 I3S Neutral Neutral P23471 R6L Neutral Neutral P23471 D1432G Neutral Neutral Q9NS18 K95E Neutral Neutral O15037 K261T Neutral Neutral O15037 L270W Neutral Neutral Q8TEP8 V769M Neutral Neutral Q8TEP8 T457A Neutral Neutral Q8N423 W306C Neutral Disease Q8N423 H20R Neutral Neutral Q8N423 D161E Neutral Neutral Q8N423 Y300H Neutral Neutral Q8NEY1 Q937H Neutral Neutral Q8NEY1 H1290D Neutral Neutral Q8NEY1 S1273L Neutral Neutral Q8NEY1 V1527I Neutral Neutral O15209 T310A Neutral Neutral Q9P0K1 P81R Neutral Neutral P54868 F174L Disease Disease P54868 R500H Disease Disease P54868 G212R Disease Disease P54868 Y167C Disease Disease P54868 V54M Disease Disease P41247 D134G Neutral Disease P41247 R187Q Neutral Neutral P41247 V48G Neutral Neutral P00797 Q160K Neutral Disease P07339 A58V Neutral Neutral P00797 R230K Disease Neutral P00790 D376E Neutral Disease P00797 D104N Disease Disease P00797 R33W Neutral Disease P07339 F229I Disease Disease P14091 T329I Neutral Disease P00790 Q222K Neutral Disease P00790 L353V Neutral Neutral P07339 W383C Disease Disease O96009 A310T Neutral Disease P00790 A265T Neutral Neutral P00797 G217R Neutral Disease O14862 E32K Neutral Neutral Q9UJQ7 P99S Neutral Neutral Q9H0I9 R442Q Neutral Disease Q9H0I9 Q590H Neutral Neutral O00534 S499I Neutral Neutral O00534 R757C Neutral Neutral O00534 H759R Neutral Neutral O00534 R506K Neutral Neutral Q9HC10 R794H Disease Disease Q9HC10 I515T Disease Disease Q9HC10 L1011P Disease Disease Q9HC10 P1825A Disease Disease Q9HC10 P1987R Disease Disease Q9HC10 P490Q Disease Neutral Q9HC10 R1939Q Disease Disease Q9NZN5 Y973F Neutral Neutral Q14626 P65T Neutral Neutral Q14626 R395W Neutral Neutral Q9BRX2 M221L Neutral Neutral P09603 G438R Neutral Neutral P09603 L408P Neutral Neutral P09603 S496F Neutral Neutral P09603 A531V Neutral Neutral P04275 C2773R Disease Disease P04275 C2739Y Disease Disease P04275 C1060R Disease Disease P04275 C2362F Disease Disease P04275 R1374H Disease Disease P04275 V1314L Disease Disease P04275 V1316M Disease Disease P04275 S1613P Disease Disease P04275 V1607D Disease Disease P04275 W377C Disease Neutral P04275 R1597G Disease Disease P04275 R1308C Disease Disease P04275 R1374C Disease Disease P04275 P1648S Disease Neutral P04275 N528S Disease Disease P04275 R1341Q Disease Neutral P04275 L1540P Disease Disease P04275 I1628T Disease Disease P04275 E1638K Disease Disease P04275 C788Y Disease Disease P04275 R1306W Disease Disease P04275 F1514C Disease Disease P04275 V1318L Disease Neutral P04275 W1313C Disease Disease P04275 R273W Disease Disease P04275 L1460V Disease Neutral P04275 G1609R Disease Disease P04275 P2063S Disease Neutral P04275 A1461V Disease Neutral P04275 N2546Y Disease Neutral P04275 H1268D Disease Disease P04275 G550R Disease Disease P04275 C1272R Disease Disease P04275 R1597Q Disease Disease P04275 G1324S Disease Disease P04275 V1665E Disease Neutral P04275 P1266L Disease Disease P04275 R1597W Disease Disease P26442 I181V Neutral Neutral P08833 I253M Neutral Neutral P08833 V183I Neutral Neutral O95867 L63M Neutral Neutral Q9P206 E1021K Neutral Neutral Q9P206 L310I Neutral Neutral Q9P206 P57S Neutral Neutral Q9P206 M232V Neutral Neutral Q9P206 P770L Neutral Neutral Q9P206 S114P Neutral Neutral Q92820 C6R Neutral Neutral Q92820 T151I Neutral Neutral Q92820 A31T Neutral Neutral Q9Y6N7 E1533D Disease Neutral Q9Y6N7 S1055N Disease Neutral P56178 S234R Neutral Neutral Q9NQ60 T274K Neutral Neutral Q9NQ60 N101D Neutral Neutral P10070 R151G Disease Neutral P10070 M1116I Disease Neutral P10070 P604S Disease Neutral P10070 P1226L Disease Neutral Q9UHE5 F143S Neutral Neutral Q9NS73 R22S Neutral Neutral Q9NS73 L7H Neutral Neutral Q6PIF6 E1647D Neutral Neutral Q6PIF6 Q2105R Neutral Neutral Q6PIF6 R1264Q Neutral Neutral Q6PIF6 G21S Neutral Neutral Q9BR10 P94L Neutral Disease Q495M9 L48P Disease Disease Q9NVV4 Y221H Neutral Neutral Q9NVV4 R162C Neutral Neutral Q9NVV4 C419R Neutral Disease Q9NVV4 S546N Neutral Neutral Q8N2M4 V215A Neutral Neutral P05230 G21E Neutral Disease Q8N448 S198P Neutral Neutral P19235 P488S Disease Neutral P19235 N487S Disease Neutral P19235 P380A Neutral Neutral Q9HA65 P99L Neutral Neutral Q96P56 E8G Neutral Neutral Q96P56 V57I Neutral Neutral Q6UY01 L322F Neutral Neutral Q6UY05 T120M Neutral Neutral Q5U5Z8 R349H Neutral Neutral Q5W0U4 Q293H Neutral Disease Q5W0U4 T374I Neutral Neutral Q96RP8 M418T Neutral Neutral Q96RP8 P189R Neutral Neutral Q8NI60 H85Q Neutral Neutral Q9HBQ8 A110V Neutral Neutral Q9UGP5 R438W Neutral Neutral Q9UGP5 T221P Neutral Neutral Q9NPJ1 R155L Disease Disease Q9NPJ1 R518H Disease Neutral Q9NPJ1 I339V Disease Neutral Q9NPJ1 Y37C Disease Disease Q9NPJ1 D492N Disease Neutral Q9NPJ1 G52D Disease Neutral Q9NPJ1 G49V Neutral Disease Q9NPJ1 C499S Disease Neutral Q9NPJ1 S460P Disease Neutral Q9NPJ1 S236P Disease Disease Q9NPJ1 H84Y Disease Neutral Q9NPJ1 A181P Disease Disease Q9NPJ1 T57A Disease Disease Q9NPJ1 A242S Disease Neutral Q9NPJ1 R517C Neutral Neutral Q9NPJ1 T237A Disease Neutral Q9NPJ1 D286A Disease Neutral Q9NPJ1 G532V Neutral Neutral Q9NPJ1 S511A Disease Neutral Q9NPJ1 L277P Disease Disease Q9NPJ1 I32M Disease Neutral Q9NPJ1 G345E Disease Disease Q9NPJ1 T237P Disease Neutral O43379 G1370S Neutral Neutral O43379 S850L Neutral Neutral O43379 F1385L Neutral Neutral Q9NUQ2 Y77C Neutral Disease Q9NSD5 V398I Neutral Neutral Q8NHS9 M148V Neutral Neutral Q8NHS9 Q155R Neutral Neutral Q8NHS9 T160I Neutral Neutral Q8NHS9 R112T Neutral Neutral Q6ZS02 L147V Neutral Neutral O15287 L71P Disease Disease Q9UQ53 L491F Neutral Neutral Q5JRX3 Q516H Neutral Neutral Q5JRX3 V963I Neutral Neutral Q5JRX3 I952M Neutral Neutral Q5JRX3 V397A Neutral Neutral Q5JRX3 L145V Neutral Neutral Q5JRX3 R1037Q Neutral Neutral Q5JRX3 V621I Neutral Neutral Q5JRX3 F169S Neutral Disease Q5JRX3 Q8R Neutral Neutral Q5JRX3 P969L Neutral Disease Q5JRX3 V328I Neutral Neutral Q8NET6 A271V Neutral Neutral Q8NET6 R317Q Neutral Neutral Q8NET6 A271G Neutral Neutral Q8NET6 A271E Neutral Neutral P50454 A41P Neutral Disease Q6MZT1 V255I Neutral Neutral Q9BTV4 M179T Neutral Neutral Q9BTV4 A318V Neutral Neutral Q9BTV4 K168N Neutral Neutral Q9BTV4 Y233C Neutral Neutral Q6UWV2 D228V Neutral Neutral Q6UWV2 M155V Neutral Neutral P51798 P249R Disease Disease P51798 R526W Disease Disease P51798 R767Q Disease Disease P51798 L490F Disease Disease P51798 L766P Disease Disease P51798 R762Q Disease Disease P51798 I261F Disease Disease P51798 R767W Disease Disease P51798 R286Q Disease Disease P51798 G215R Disease Disease P51798 G677V Disease Disease P51798 L614P Disease Disease P51798 V418M Neutral Neutral P51798 M332V Disease Disease P51798 G240R Disease Disease P51798 S744F Disease Neutral Q5VYY1 E73G Neutral Neutral Q5VYY1 Q148P Neutral Disease Q5VYY1 R177I Neutral Disease Q5VYY1 Y79H Neutral Neutral Q4KMZ1 P464L Neutral Neutral Q4KMZ1 F209C Neutral Neutral Q4KMZ1 C217Y Neutral Neutral P69905 K61N Neutral Disease P68871 W16G Neutral Disease P68871 E7V Neutral Disease P68871 V19M Neutral Disease P68871 A14D Neutral Disease P69905 G60D Neutral Disease P68871 K18E Neutral Disease P68871 E8G Neutral Disease P69905 N69K Neutral Disease P69905 P45L Neutral Disease P02042 T5I Neutral Disease P69891 I76T Neutral Neutral P69905 V11F Neutral Disease P68871 H3Q Neutral Disease P68871 H3L Neutral Disease P68871 V68G Neutral Disease P69905 S103R Neutral Disease P68871 K9E Neutral Disease P68871 P6R Neutral Disease P69905 L92P Neutral Disease P69892 I76T Neutral Neutral P68871 V12D Neutral Disease Q9H1H9 M1415V Neutral Neutral P28223 T25N Neutral Neutral P28223 H452Y Neutral Neutral P28223 A447V Neutral Neutral P28223 I197V Neutral Neutral Q14849 R117Q Neutral Neutral Q14849 G216A Neutral Neutral Q8NCM8 H341Y Neutral Neutral Q8NCM8 R789K Neutral Neutral Q8NCM8 T302P Neutral Disease Q8NCM8 T1288A Neutral Neutral Q8NCM8 Q4139P Neutral Disease Q8NCM8 K1413R Neutral Disease Q8NCM8 R1221K Neutral Neutral Q8NCM8 Q2871R Neutral Disease Q8NCM8 R456Q Neutral Neutral Q8NCM8 Q304L Neutral Neutral Q8NCM8 A3680V Neutral Neutral Q8NCM8 S3976N Neutral Neutral Q96M89 D99Y Neutral Neutral Q96M89 R115K Neutral Neutral P48728 R320H Disease Disease P48728 H42R Disease Disease P48728 G47R Disease Disease P48728 E211K Disease Neutral P48728 D276H Disease Disease P48728 N145I Disease Disease P48728 G269D Disease Disease O75952 S490A Neutral Neutral O75952 T74M Neutral Neutral O75952 K448R Neutral Neutral Q02094 V270I Disease Neutral Q02094 G280R Disease Disease Q9H310 G315R Neutral Disease P18577 N68S Neutral Neutral Q9H310 V143D Neutral Disease P18577 W16C Neutral Disease Q9UBD6 R202C Neutral Disease Q9H310 G76D Neutral Disease Q02094 S79N Disease Disease P18577 L60I Neutral Neutral Q02094 G380V Disease Disease Q02094 G279E Disease Disease Q6P1J6 D879H Neutral Neutral Q6P1J6 M708V Neutral Neutral Q6P1J6 G821R Neutral Disease Q6P1J6 A1318V Neutral Neutral Q6P1J6 V212L Neutral Disease Q9H114 T59A Neutral Neutral Q9H114 W88R Neutral Neutral Q9H114 R66K Neutral Neutral O60676 A142P Neutral Neutral Q9H114 Y62F Neutral Neutral Q9H114 T96M Neutral Neutral P08697 R434K Neutral Neutral P08697 A27V Neutral Neutral P08697 R33W Neutral Neutral P08697 V411M Disease Neutral Q9NR23 V328L Neutral Neutral Q9NR20 N189S Neutral Disease Q9NR20 D454V Neutral Neutral Q9NR20 A61T Neutral Neutral Q9NR20 V95I Neutral Neutral Q9NR20 A70S Neutral Neutral O60880 T68I Disease Disease O60880 P101L Disease Disease O60880 R32T Disease Disease O60880 R55L Disease Disease Q3KR16 A35T Neutral Neutral Q9H857 S91R Neutral Disease Q9Y314 T168M Neutral Neutral Q8N4W9 V61G Neutral Neutral P10828 P453H Disease Disease P10828 K342I Disease Neutral P10828 G347E Disease Disease P10828 G345S Disease Disease P10828 K443E Disease Disease P10828 R320C Disease Disease P10828 V348E Disease Disease P10828 Q340H Disease Neutral P10828 T337I Neutral Disease P10828 R320H Disease Disease P10828 C446R Disease Disease P10828 P453T Disease Disease P10828 R438H Disease Neutral P10828 R338W Disease Disease P10828 G332R Disease Disease P10828 M442V Disease Neutral P10828 G345R Disease Disease P10828 T426I Disease Neutral P10828 G345V Disease Disease P10828 P453S Disease Disease P10828 A234T Disease Neutral P10828 R316H Disease Disease P10828 A317T Disease Neutral P10828 R243W Disease Neutral P34896 L474F Neutral Neutral A1L390 R1036W Neutral Neutral Q7Z434 S409F Neutral Neutral Q53EQ6 I519M Neutral Neutral Q7RTM1 K493T Neutral Neutral Q7RTM1 V434M Neutral Neutral Q7RTM1 Q516H Neutral Neutral Q7RTM1 D309E Neutral Neutral Q7RTM1 I241V Neutral Neutral Q9UPI3 V16A Neutral Neutral P33076 A500G Neutral Neutral P33076 A658G Neutral Neutral P33076 L45V Neutral Neutral P55085 T291A Neutral Neutral P55085 S21F Neutral Neutral P55085 R270Q Neutral Disease Q96LM5 R134H Neutral Neutral Q96LM5 G93E Neutral Neutral Q96LM5 S75G Neutral Neutral Q96LM5 A46V Neutral Neutral Q96LM5 Y84C Neutral Neutral Q9NPR2 S792A Neutral Neutral P22830 P192T Disease Disease P22830 M288K Disease Disease P22830 I71K Disease Disease P22830 T283I Disease Disease P22830 F260L Disease Disease P22830 C406Y Disease Disease P22830 F417S Disease Disease P22830 H386P Disease Disease P22830 Q139L Disease Disease P22830 L182R Disease Disease P22830 S151P Disease Disease P22830 V362G Disease Neutral P22830 I186T Disease Neutral P22830 G55C Disease Neutral P22830 E178K Disease Neutral P22830 Y191H Disease Disease P22830 P334L Disease Disease P22830 C236Y Disease Disease P22830 K379N Disease Neutral P22830 P62R Disease Neutral P22830 C406S Disease Disease P22830 M267I Disease Disease P22830 R96Q Neutral Neutral Q9H0D6 R743M Neutral Neutral Q9P2N6 V707I Neutral Neutral Q6ZMC9 F273L Neutral Neutral Q96P44 L277P Neutral Disease Q96P44 P827A Neutral Neutral Q96P44 G560S Neutral Disease Q96P44 L821P Neutral Neutral Q96P44 I495T Neutral Disease Q96P44 T343M Neutral Neutral Q96P44 A747D Neutral Neutral P49768 G206A Disease Disease P49768 L271V Disease Disease P49810 M239I Disease Disease P49768 L219P Disease Disease P49768 M146V Disease Disease P49768 C92S Disease Disease P49768 Y115H Disease Disease P49768 A260V Disease Disease P49768 L282R Disease Disease P49768 A231T Disease Neutral P49768 M139V Disease Neutral P49768 E120K Disease Disease P49768 P436Q Disease Disease P49768 S169P Disease Disease P49810 M239V Disease Disease P49768 F205L Neutral Disease P49768 A246E Disease Disease P49768 G209R Disease Disease P49810 T122P Disease Disease P49768 S390I Disease Disease P49768 V96F Disease Disease P49768 N135D Disease Disease P49768 S169L Disease Disease P49768 C410Y Disease Disease P49768 I143F Disease Disease P49768 T147I Disease Disease P49768 W165C Disease Disease P49768 L250S Disease Disease P49768 R269H Disease Disease P49768 L174M Disease Disease P49768 L113P Disease Disease P49768 Y115C Disease Disease P49768 G384A Disease Disease P49768 N405S Disease Disease P49768 S289C Disease Disease P49768 H163R Disease Disease P49768 A426P Disease Disease P49768 M139I Disease Neutral P49768 L262F Disease Neutral P49768 A79V Disease Disease P49768 F105L Disease Disease P49768 P264L Disease Disease P49768 A431E Disease Disease P49768 M233L Disease Disease P49768 V82L Disease Disease P49810 V148I Disease Neutral P49768 E280A Disease Disease P49768 I143T Disease Disease P49768 L173W Disease Disease P49768 L286V Disease Disease P49768 P267S Disease Disease P49768 L166P Disease Disease P49768 I213T Disease Disease P49768 E318G Neutral Neutral P49768 T116N Disease Disease P49768 G378E Disease Disease P49768 C263R Disease Disease P49768 L392V Disease Disease P49768 M139K Disease Disease P49768 M233T Disease Disease P49768 H163Y Disease Disease P49768 M146L Disease Disease P49768 R278T Disease Disease P49768 G209V Disease Disease P49768 E280G Disease Disease P49810 N141I Disease Disease P49768 M139T Disease Neutral P49768 A231V Disease Disease P49768 R269G Disease Disease P49768 G266S Disease Disease P49768 E120D Disease Neutral P49768 P117L Disease Disease P49768 P436S Disease Disease P49768 A409T Disease Disease P49768 A285V Disease Disease P49768 L171P Disease Disease P49810 R62H Disease Neutral P49768 P267T Disease Disease P49768 M146I Disease Disease O00622 R334W Neutral Neutral P29279 H83D Neutral Neutral Q9BSK4 H500Y Neutral Disease Q9BQ50 R180C Neutral Neutral Q9NXA8 F285L Neutral Neutral Q8N5I4 E297K Neutral Disease Q5SRE5 N1587K Neutral Neutral Q5SRE5 A1419V Neutral Neutral Q4L235 A747V Neutral Neutral Q4L235 D1030Y Neutral Neutral Q4L235 T865A Neutral Neutral Q4L235 V774I Neutral Neutral Q4L235 K368R Neutral Neutral Q6L9W6 R265Q Neutral Neutral Q6L9W6 G59S Neutral Neutral Q6L9W6 K411R Neutral Neutral O43252 S587L Neutral Disease O95340 E10K Neutral Neutral O95340 V291M Neutral Neutral O43252 L270F Neutral Disease O95340 M281L Neutral Neutral O95340 R432K Neutral Neutral Q96RD7 H5Q Neutral Neutral Q96RD7 I272V Neutral Neutral P04632 M224V Neutral Neutral Q5VZ03 S76C Neutral Neutral Q8TCU4 D2672H Neutral Neutral Q8TCU4 S2574N Neutral Neutral Q8TCU4 V671G Neutral Neutral Q8TCU4 S2111R Neutral Neutral P55771 G51S Disease Disease P55771 A240P Neutral Disease P40200 T280M Disease Neutral P40200 A142P Neutral Neutral Q93033 S525R Neutral Disease Q93033 R988C Neutral Neutral Q93033 N225S Neutral Neutral Q93033 V415M Neutral Neutral Q93033 R518Q Neutral Neutral Q93033 V965I Neutral Neutral P42785 T444S Neutral Neutral P42785 E112D Neutral Neutral P52740 P135L Neutral Neutral Q9BV87 T262I Neutral Neutral Q9BV87 P366L Neutral Disease Q9BV87 P292L Neutral Neutral Q9BV87 P383L Neutral Neutral Q7Z3K6 N530S Neutral Neutral Q7Z3K6 N432D Neutral Neutral Q7Z3K6 N414K Neutral Neutral Q7Z3K6 D126G Neutral Neutral O00182 G5S Neutral Neutral Q693B1 G22S Neutral Neutral Q6KC79 A1246G Disease Neutral Q6KC79 G2312R Disease Disease Q6KC79 R2298H Disease Disease Q6KC79 R1856T Disease Disease Q6KC79 C1311R Disease Disease Q6KC79 R1789L Disease Disease Q6KC79 Y2440H Disease Disease Q6KC79 L1312P Disease Disease Q6KC79 L1348R Disease Disease Q6KC79 R2298C Disease Neutral Q6KC79 A2390T Disease Neutral Q6KC79 D1803V Disease Disease Q6KC79 G2381A Disease Neutral Q6KC79 Y2430C Disease Disease Q8WVP7 T228A Neutral Neutral Q96DC7 T299S Neutral Neutral Q96F45 N509K Neutral Disease Q9H9Q4 C123R Disease Disease Q9H9Q4 H89R Neutral Neutral Q9H9Q4 A14T Neutral Neutral Q9H9Q4 R57G Disease Neutral Q9H9Q4 Q256L Neutral Neutral Q53H12 V3M Neutral Neutral Q9Y4U1 R189S Disease Neutral Q9Y4U1 H122R Disease Disease Q9Y4U1 R161Q Disease Neutral Q9Y4U1 R206W Disease Disease Q9Y4U1 W157C Disease Disease Q9Y4U1 L193P Disease Disease Q9Y4U1 R206P Disease Disease Q9Y4U1 L116P Disease Disease Q9Y4U1 Y130H Disease Neutral Q9Y4U1 G147D Disease Disease Q9Y4U1 R161G Disease Neutral Q9Y4U1 S271G Neutral Neutral Q9Y4U1 G147A Disease Disease Q9Y4U1 G156D Disease Disease Q9Y4U1 Q27R Disease Neutral Q8N556 S403C Neutral Neutral Q8N556 V518M Neutral Neutral P07585 E273Q Neutral Disease P07585 T268M Neutral Neutral P31994 Y205F Neutral Neutral P31994 I232T Neutral Neutral P31994 Y258D Neutral Neutral O94762 D480G Neutral Neutral Q9NP59 D157G Disease Disease Q9NP59 D270V Disease Neutral Q9NP59 G267D Disease Neutral Q9NP59 N144D Disease Neutral Q9NP59 R561G Neutral Neutral Q9NP59 G80V Disease Disease Q9NP59 P443L Neutral Neutral Q9NP59 M432V Neutral Neutral Q9NP59 D181V Disease Disease Q9NP59 Q182H Disease Neutral Q9NP59 Q248H Neutral Neutral Q9NP59 Y64N Disease Disease Q9NP59 A77D Disease Disease Q9NP59 N144T Disease Neutral Q9NP59 N144H Disease Neutral Q9NP59 G323V Disease Disease P32418 E692V Neutral Disease O75330 R332H Neutral Neutral O75330 R92C Neutral Neutral O75330 V368A Neutral Neutral O75330 N305K Neutral Neutral O75330 A484V Neutral Neutral P52961 P105L Neutral Neutral P52961 P126R Neutral Neutral Q96AE7 I145L Neutral Neutral O95813 A65G Neutral Neutral O95813 R19W Neutral Neutral O95813 V179I Neutral Neutral Q8TBN0 Q49R Neutral Neutral Q8TBN0 H323Y Neutral Neutral Q6P9G0 F20L Neutral Neutral Q96MA6 D130G Neutral Disease Q96MA6 I5T Neutral Neutral Q9BPU9 M11I Neutral Neutral Q6PJW8 S87L Neutral Neutral Q6PJW8 R399C Neutral Neutral Q6PJW8 S28N Neutral Neutral P02790 R83W Neutral Disease P46098 R344H Neutral Neutral P46098 R409Q Neutral Neutral P46098 P391R Neutral Neutral O95264 V183I Neutral Neutral O95264 Y129S Neutral Disease P46098 A33T Neutral Neutral O95264 S156R Neutral Disease P46098 S253N Neutral Disease O95264 I143T Neutral Disease Q5VW38 A189P Neutral Neutral Q8IUX8 D535N Neutral Disease Q8IUX8 R164C Neutral Disease Q8IUX8 E66K Neutral Neutral Q8IUX8 L508F Neutral Neutral Q53H54 W28R Neutral Neutral P10767 R191W Neutral Disease P10767 A63V Neutral Neutral P10767 V36A Neutral Neutral P10767 D174V Neutral Disease Q8TF05 I470V Neutral Neutral Q8TF05 S595N Neutral Neutral Q8TF05 E43K Neutral Neutral Q92854 A72T Neutral Neutral Q04760 C19Y Neutral Neutral Q04760 E111A Neutral Disease P63092 R385H Disease Neutral P63092 K338N Disease Disease P19087 G183D Neutral Disease P63092 W281R Disease Disease Q14344 V221L Neutral Disease P63092 V159M Disease Disease P63092 R201L Disease Disease P63092 R231H Disease Disease P30679 C147Y Neutral Disease P63092 R280G Disease Disease P63092 R280K Disease Neutral P63092 R165C Disease Disease P63092 E259V Disease Disease P63092 F246S Disease Disease P11488 G38D Disease Disease P63092 R258W Disease Disease P63092 T242I Disease Disease P63092 R201S Disease Disease P63092 S250R Disease Disease P63092 R201H Disease Disease P63092 P115L Disease Neutral P63092 R201G Disease Disease P63092 D156N Disease Disease P63092 Q227R Disease Disease P63092 R201C Disease Disease P63092 A366S Disease Disease P63092 L99P Disease Disease Q06190 D745N Neutral Neutral P51570 G349S Disease Disease P51570 R68C Disease Disease P51570 R239Q Disease Disease P51570 V338A Neutral Neutral P51570 V32M Disease Neutral P51570 H44Y Disease Disease P51570 G36R Disease Disease P51570 P28T Disease Disease P51570 G346S Disease Disease P51570 A384P Disease Disease P51570 G274D Neutral Neutral P51570 A198V Disease Disease P51570 I184M Neutral Disease P51570 T288M Disease Disease Q9NUZ1 T78M Neutral Disease Q9NUZ1 P358L Neutral Disease Q9Y2M2 P29L Neutral Neutral Q9P0W5 A481V Neutral Neutral Q8TBZ2 A387T Neutral Neutral Q8TBZ2 R688W Neutral Neutral Q8TBZ2 S910R Neutral Neutral Q8TBZ5 E243A Neutral Neutral Q8TBZ5 L28P Neutral Neutral Q86VV4 A111D Neutral Neutral Q86VV4 A271V Neutral Neutral Q86VV4 R70T Neutral Neutral P09210 S112T Neutral Neutral P09210 V149A Neutral Disease O15217 T163A Neutral Neutral P08263 T19I Neutral Neutral Q7RTV2 V55I Neutral Neutral O15217 L100P Neutral Disease P09210 P110S Neutral Neutral P09210 E210A Neutral Neutral Q14520 E393Q Neutral Neutral Q14520 G534E Neutral Disease Q14520 V90I Neutral Neutral Q96PC2 Y378S Neutral Disease Q96PC2 A308V Neutral Neutral Q96PC2 V312I Neutral Neutral Q96PC2 R60W Neutral Neutral O15455 L412F Neutral Disease O15455 S737T Neutral Neutral Q9H5V8 R525Q Neutral Neutral Q9H5V8 G709D Neutral Neutral A4D1T9 T119P Neutral Neutral A0FGR8 C210S Neutral Neutral A0FGR8 S638G Neutral Neutral Q12809 P632S Disease Disease Q12809 P1016L Neutral Neutral Q12809 K525N Neutral Disease Q12809 K638E Disease Disease Q12809 N33T Disease Disease Q12809 G53R Disease Disease Q12809 R531Q Disease Disease Q12809 S818L Disease Disease Q12809 P1026L Neutral Neutral Q12809 R528P Neutral Disease Q12809 G628S Disease Disease Q12809 T474I Disease Disease Q12809 F805C Disease Disease Q12809 H70R Disease Neutral Q12809 Y611H Disease Disease Q12809 F805S Disease Disease Q12809 F640L Disease Disease Q12809 P1020S Neutral Neutral Q12809 T613M Disease Disease Q12809 N629S Disease Neutral Q12809 R181Q Neutral Neutral Q12809 G572C Disease Disease Q12809 G604S Disease Neutral Q12809 F29L Disease Disease Q12809 G47V Disease Disease Q12809 R312C Disease Neutral Q12809 G572R Disease Disease Q12809 Y569H Disease Disease Q12809 T65P Disease Disease Q12809 A78P Disease Disease Q12809 R752W Disease Disease Q12809 G626S Disease Disease Q12809 R534C Disease Disease Q12809 G584S Disease Neutral Q12809 T436M Disease Neutral Q12809 N470D Disease Disease Q12809 M645L Disease Disease Q12809 A490T Neutral Disease Q12809 L86R Disease Disease Q12809 N629K Disease Disease Q12809 I593T Disease Neutral Q12809 L552S Disease Disease Q12809 P1016S Neutral Neutral Q12809 L615V Disease Disease Q12809 P72Q Disease Neutral Q12809 A614V Disease Disease Q12809 R176W Disease Neutral Q12809 W585C Disease Disease Q12809 V630L Disease Disease Q12809 K897T Neutral Neutral Q12809 C66G Disease Disease Q12809 R823W Disease Disease Q12809 A561V Disease Disease Q12809 A561T Disease Disease Q12809 P347S Disease Neutral Q12809 R922W Disease Neutral Q12809 N861I Disease Disease Q12809 P451L Disease Disease Q12809 I593R Disease Neutral Q12809 P917L Disease Neutral Q12809 R582C Disease Neutral Q12809 R752Q Disease Disease Q12809 A558P Disease Disease Q12809 N588D Disease Neutral Q12809 N629D Disease Neutral Q12809 N588K Disease Neutral Q12809 V630A Disease Neutral Q12809 N633S Disease Neutral Q12809 F627L Disease Disease Q12809 R100G Disease Disease Q12809 L564P Disease Disease Q12809 R56Q Disease Disease Q12809 R1055Q Neutral Neutral Q12809 V612L Disease Disease Q12809 G601S Disease Neutral Q12809 E637K Disease Disease Q12809 D609N Disease Neutral Q12809 V822M Disease Disease Q9NPC4 G187D Neutral Disease Q9NPC4 Q163R Neutral Neutral Q9NPC4 P251L Neutral Disease Q9NPC4 M37V Neutral Neutral Q99708 H387Y Neutral Neutral Q9Y5Z7 G268A Neutral Neutral O43182 D791E Neutral Neutral Q9P0U3 D350G Neutral Neutral Q9P0U3 I193V Neutral Neutral Q8IX90 T254A Neutral Neutral Q9UKA8 T236N Neutral Neutral Q9P0N8 A54T Neutral Neutral Q8IYF3 E451K Neutral Neutral Q8IYF3 K130R Neutral Neutral Q8IUN9 C35R Neutral Neutral Q9NUV9 E128D Neutral Neutral Q9BY44 E582K Neutral Neutral Q9BY44 S97T Neutral Neutral P20930 G3436A Neutral Neutral Q96J65 A102E Neutral Neutral Q96J65 I9L Neutral Neutral Q96J65 K894M Neutral Neutral Q96J65 F1349L Neutral Disease Q96J66 R19H Neutral Neutral Q96J65 E1191A Neutral Neutral Q96J65 T989S Neutral Neutral Q96J66 G180R Neutral Disease Q96J65 N587Y Neutral Neutral Q96J65 Y1013H Neutral Disease Q96J65 R1117C Neutral Neutral Q6UXI9 M476T Neutral Neutral Q6UXI9 Q159H Neutral Neutral Q6UXI9 V234I Neutral Neutral Q6UXI9 G473S Neutral Neutral Q53HV7 R105W Neutral Disease Q53HV7 G15V Neutral Neutral Q6VMQ6 R530K Neutral Neutral Q6VMQ6 E278K Neutral Neutral Q6VMQ6 N348I Neutral Neutral P40305 S106F Neutral Neutral P10645 R398W Neutral Neutral P10645 E176K Neutral Neutral P10645 G315S Neutral Neutral P10645 D369N Neutral Neutral P10645 A274G Neutral Neutral P10645 R271W Neutral Neutral P10645 P388L Neutral Neutral P10645 G382S Neutral Neutral P10645 E264D Neutral Neutral P10645 L332P Neutral Neutral Q9Y297 A543S Neutral Neutral Q9Y297 P592H Neutral Neutral Q8N456 R31H Neutral Disease Q8N456 G7V Neutral Disease P22888 A572V Disease Disease P22888 I575L Disease Disease P22888 T577I Disease Disease P22888 L457R Disease Disease P22888 M571I Disease Neutral P22888 D578H Disease Disease P22888 A593P Disease Disease P22888 E354K Disease Disease P22888 I625K Disease Disease P22888 D578E Disease Disease P22888 S306N Neutral Neutral P22888 D578Y Disease Disease P22888 C343S Disease Disease P22888 C543R Disease Disease P22888 C131R Disease Disease P22888 C581R Disease Disease P22888 D564G Disease Neutral P22888 A568V Disease Disease P22888 D578G Disease Disease P22888 S616Y Disease Disease P22888 N284S Neutral Disease P22888 I542L Disease Disease P22888 M398T Disease Disease P22888 A373V Disease Disease Q9C0J1 L87P Neutral Neutral Q9C0J1 S83T Neutral Neutral Q9C0J1 P6A Neutral Neutral O95343 R257P Disease Disease O95343 V250A Disease Disease O95343 R257W Disease Disease O95343 H173P Disease Disease O95343 G69D Disease Neutral O95343 V92G Disease Disease O95343 P231R Disease Disease O95343 I105V Disease Neutral O95343 L226V Disease Neutral O95343 T202I Disease Disease Q8N6M8 R114Q Neutral Neutral Q9UKX5 L1094V Neutral Neutral Q9UKX5 M471L Neutral Neutral P17301 K534E Neutral Disease O75578 A702T Neutral Disease Q9UKX5 R524L Neutral Disease P17301 N927S Neutral Neutral P56199 E1108G Neutral Neutral O75578 R725Q Neutral Neutral Q9UKX5 L972P Neutral Neutral O75578 R381Q Neutral Neutral Q9UKX5 V433M Neutral Neutral O75578 R668W Neutral Neutral O75578 R691H Neutral Neutral P17301 K1127Q Neutral Neutral P56199 T480M Neutral Neutral Q9UKX5 Q891K Neutral Neutral Q9UKX5 I1003M Neutral Neutral P17301 N691K Neutral Disease P56199 I961M Neutral Neutral Q8N157 I49N Neutral Neutral Q8N157 R723Q Disease Disease Q8N157 T856S Neutral Neutral Q8N157 Q1018P Neutral Neutral Q8N157 S761L Neutral Disease Q8N157 S1123F Neutral Neutral Q8N157 P1140S Neutral Neutral Q8N157 R830W Neutral Disease Q8N157 V443D Disease Disease Q8N157 R548H Neutral Neutral Q8N157 Y933C Neutral Neutral Q8NBJ9 T631M Neutral Neutral Q8NBJ9 V636I Neutral Neutral Q8N6P7 R518G Neutral Neutral Q8N6P7 M407V Neutral Neutral Q8N6P7 S130P Neutral Neutral Q8N6P7 A209S Neutral Neutral Q8N6P7 V205I Neutral Neutral Q8N6P7 L222P Neutral Disease Q16790 Q326R Neutral Neutral Q16790 V33M Neutral Neutral Q96MR6 A183S Neutral Neutral Q96MR6 N241D Neutral Neutral Q96MR6 C345S Neutral Neutral Q8TBB6 G330R Neutral Disease Q7Z333 R332W Disease Disease Q7Z333 T3I Disease Neutral Q7Z333 M274I Disease Neutral Q7Z333 P1331L Neutral Neutral Q7Z333 I2587V Neutral Neutral Q7Z333 R1252G Neutral Neutral Q7Z333 E1192D Neutral Neutral Q7Z333 W305C Disease Disease Q7Z333 S2612G Neutral Neutral Q7Z333 P2213L Disease Disease Q7Z333 A660G Neutral Neutral Q7Z333 P1061L Neutral Neutral Q7Z333 P413L Disease Disease Q7Z333 R1294C Disease Neutral Q7Z333 L389S Disease Disease Q7Z333 Q653K Disease Neutral Q7Z333 T1855A Neutral Neutral Q7Z333 N603D Disease Neutral Q7Z333 V1386I Neutral Neutral Q7Z333 F1152C Neutral Neutral Q7Z333 R2136H Disease Neutral Q7Z333 P2368R Disease Neutral Q7Z333 F1756S Disease Disease Q9Y6Y9 P157S Neutral Neutral Q92563 G353S Neutral Disease O43557 L120V Neutral Neutral Q06643 G70E Neutral Neutral Q06643 A111P Neutral Disease Q06643 L87F Neutral Neutral O43557 E214K Neutral Neutral Q06643 S84R Neutral Neutral O43557 S32L Neutral Neutral Q06643 A122D Neutral Neutral Q9UMX6 E155D Neutral Neutral Q8TCG2 S78P Neutral Neutral Q01459 D310Y Neutral Neutral P04155 A34D Disease Neutral P04155 T32K Disease Neutral P04155 T32I Disease Neutral P04155 E37K Disease Neutral P04155 G55V Disease Disease Q8IWZ5 A579E Neutral Neutral Q8IWZ5 V475M Neutral Neutral Q17RD7 A10V Neutral Neutral Q17RD7 R131L Neutral Neutral Q9UBC3 H814R Disease Disease Q9UBC3 L664P Disease Disease Q9UBC3 A766P Disease Disease Q9UBC3 R840Q Disease Disease Q9UBC3 A585V Disease Disease Q9UBC3 V726G Disease Disease Q9UBC3 V818M Disease Disease Q9UBC3 A603T Disease Disease Q9UBC3 V699G Disease Disease Q9UBC3 G663S Disease Disease Q9UBC3 V606A Disease Neutral Q9UBC3 D817G Disease Disease Q9UBC3 S270P Disease Disease Q9UBC3 R54P Neutral Neutral P51816 L1185M Neutral Neutral Q9BZY9 R118C Neutral Neutral Q9BZY9 V232I Neutral Neutral Q9BZY9 E421K Neutral Neutral Q9H1I8 P423S Neutral Neutral Q9H1I8 D407H Neutral Neutral Q9H1I8 R639L Neutral Neutral Q9H1I8 R509Q Neutral Neutral Q14207 Q1191R Neutral Neutral Q14207 V621I Neutral Neutral Q14207 L399M Neutral Neutral Q14207 L540F Neutral Neutral Q14207 N999K Neutral Neutral Q14207 V608A Neutral Neutral Q14207 V575I Neutral Neutral Q14207 L973V Neutral Neutral Q14207 E967Q Neutral Neutral Q14207 V987A Neutral Neutral Q14207 I295L Neutral Neutral Q14207 I483L Neutral Neutral Q14207 V447M Neutral Disease Q15911 S72A Neutral Neutral Q15911 T428P Neutral Neutral Q15911 E460Q Neutral Neutral Q15911 A3374V Neutral Neutral Q15911 P3421A Neutral Neutral Q15911 V777A Neutral Neutral O60292 G1371S Neutral Neutral O60292 P1450A Neutral Neutral Q9H2X6 R1027Q Neutral Neutral Q9H2X6 R792Q Neutral Neutral Q86Z02 G310C Neutral Neutral O14958 V76M Neutral Neutral O14958 D307H Disease Disease O14958 T66A Neutral Neutral O15264 A282V Neutral Neutral O15264 S41L Neutral Disease P53778 T244M Neutral Disease O15264 A300T Neutral Neutral P53778 D230N Neutral Neutral P27361 E323K Neutral Disease P53778 T103M Neutral Neutral Q96M96 M298R Disease Disease Q9NWX6 L232P Neutral Neutral P12110 D621N Disease Disease P12109 K121R Disease Neutral P12109 G341D Disease Neutral P12110 R680H Neutral Neutral P12110 S399N Neutral Neutral P12110 G271S Disease Disease P12109 G305V Disease Neutral O75251 P23L Neutral Neutral O75251 V122M Disease Disease Q9BXB7 M133V Neutral Neutral Q9BXB7 M526T Neutral Neutral Q9BXB7 R283Q Disease Neutral Q9BXB7 G147E Neutral Neutral Q9BXB7 N50S Neutral Neutral Q9BXB7 E90G Neutral Neutral Q9BXB7 V423M Neutral Neutral Q9BXB7 V286M Neutral Neutral Q9BXB7 Q564R Neutral Neutral Q9BXB7 A509V Neutral Neutral Q9BXB7 E78K Neutral Neutral P04066 S68L Disease Disease Q9BTY2 Y371H Neutral Neutral P04066 P10R Neutral Neutral Q9BTY2 V356M Neutral Neutral P04066 C269S Neutral Neutral P04066 G65D Disease Disease P04066 Q286R Neutral Neutral P04066 L410R Disease Disease Q9UJA3 Q63K Neutral Neutral Q9Y5K5 I197F Neutral Disease Q9Y5K1 T36A Neutral Neutral Q9Y5K1 R211W Neutral Neutral Q8ND07 K496E Neutral Neutral O15119 Y149S Disease Disease O15119 L143P Disease Disease Q6ISU1 A183T Neutral Neutral Q6ISU1 V106I Neutral Neutral Q9BT09 M145I Neutral Neutral Q9BT09 S231I Neutral Neutral Q9UGI9 P71A Neutral Neutral P15941 V1117M Neutral Neutral P15941 S1142N Neutral Neutral P61916 S67P Disease Neutral P61916 V39M Disease Neutral P61916 P86L Neutral Neutral O43613 R279Q Neutral Neutral O43613 I408V Neutral Neutral Q3KPI0 T121N Neutral Disease Q3KPI0 M198V Neutral Neutral Q86UK0 E2064K Neutral Neutral Q86UK0 G1651S Disease Neutral Q86UK0 G1251D Neutral Disease Q86UK0 S459T Neutral Neutral Q86UK0 E550G Neutral Neutral Q86UK0 G1381E Disease Disease Q86UK0 N1380S Disease Disease Q86UK0 R1514H Disease Disease Q86UK0 R1546C Neutral Disease Q86UK0 E1539K Disease Disease Q86UK0 D2365N Disease Disease Q86UK0 T777S Neutral Neutral P35869 P517S Neutral Neutral P35869 V570I Neutral Neutral P35869 R554K Neutral Neutral P35869 M786V Neutral Neutral O00421 V168M Neutral Neutral O00421 I243V Neutral Neutral O00421 F167Y Neutral Neutral Q9NTJ4 V960I Neutral Neutral Q8NCF5 R33W Neutral Neutral Q92626 Q1261R Neutral Disease O60759 D37N Neutral Neutral Q5DID0 T698P Neutral Neutral Q5DID0 N274D Neutral Neutral Q5DID0 E1115K Neutral Neutral Q5DID0 N1309H Neutral Neutral Q5DID0 M559T Neutral Neutral Q5DID0 V850I Neutral Neutral Q5DID0 R447Q Neutral Neutral Q5DID0 V173L Neutral Disease Q5DID0 I639T Neutral Neutral Q5DID0 N274H Neutral Neutral Q5DID0 D1208N Neutral Neutral Q5DID0 S1027N Neutral Neutral Q5DID0 G1068S Neutral Disease Q8N1D5 F191L Neutral Neutral P56373 A383V Neutral Neutral Q6DN90 V882I Neutral Neutral Q53ET0 M147V Neutral Neutral Q53ET0 R379C Neutral Neutral Q6UUV7 S72N Neutral Neutral Q6UUV7 L346S Neutral Disease P59796 E136D Neutral Neutral P59796 P157S Neutral Disease P59796 F13L Neutral Neutral P59796 V140M Neutral Disease P59796 V188A Neutral Disease P22352 F128L Neutral Disease P59796 D161G Neutral Neutral O75715 L85V Neutral Neutral P59796 Q58H Neutral Disease P59796 Y72N Neutral Disease P59796 Y53H Neutral Neutral P59796 Q6L Neutral Neutral O43423 E204G Neutral Neutral O43423 Y140H Neutral Disease O43423 A23V Neutral Neutral O43423 R71K Neutral Neutral Q8TCT9 A259P Neutral Disease Q86V21 I118V Neutral Neutral Q99988 T48S Neutral Neutral Q15198 H23Y Disease Neutral Q96FG2 R66C Neutral Neutral Q96FG2 T70I Neutral Neutral Q7RTZ1 T539I Neutral Neutral Q7RTZ1 N410T Neutral Neutral Q7RTZ1 R413G Neutral Neutral Q7RTZ1 H526Q Neutral Neutral Q7RTZ1 R19Q Neutral Neutral Q7RTZ1 G381E Neutral Neutral Q7RTZ1 P292S Neutral Neutral Q7Z3D6 D502N Neutral Neutral Q7Z3D6 R10C Neutral Neutral O76041 N654K Neutral Disease O76041 T728A Neutral Neutral O76041 A219D Neutral Disease O76041 M351V Neutral Neutral O76041 Q187H Neutral Neutral P42167 L427F Neutral Neutral Q8N5W8 P2L Neutral Neutral O15503 A27T Neutral Neutral P31152 V38M Neutral Neutral P31152 R371P Neutral Neutral Q86V48 D868N Neutral Neutral Q86V48 G458S Neutral Neutral Q86V48 Q461K Neutral Neutral P48448 A50T Neutral Disease Q8N8I6 R119C Neutral Disease Q8N8I6 V50L Neutral Neutral A0AVK6 I674V Neutral Neutral Q9BVK2 T47P Disease Disease Q9BVK2 N222S Neutral Neutral Q9BVK2 I439T Neutral Neutral Q9BVK2 G275D Disease Disease Q8NBX0 G418R Neutral Disease Q5JWF2 P459R Disease Neutral Q5JWF2 A436D Disease Neutral Q8IX03 R250C Neutral Neutral Q9Y6H6 R83H Disease Neutral P78559 S1938R Neutral Neutral P78559 S2056R Neutral Neutral P78559 A353S Neutral Neutral P78559 T830A Neutral Neutral P78559 K336T Neutral Neutral P78559 D1461N Neutral Neutral P78559 I1102T Neutral Neutral P78559 A335S Neutral Neutral P78559 K1605N Neutral Neutral P78559 P1827A Neutral Neutral P78559 Q1553H Neutral Neutral P78559 H2214Y Neutral Neutral P78559 A1881P Neutral Neutral P78559 K364Q Neutral Neutral P78559 F72L Neutral Disease P78559 A357S Neutral Neutral P78559 R1185H Neutral Neutral P78559 N1078S Neutral Neutral P78559 K485Q Neutral Neutral P78559 A1912V Neutral Neutral P78559 A1690S Neutral Neutral P78559 D1245N Neutral Neutral P78559 W1650C Neutral Neutral P78559 D2327V Neutral Neutral Q17RP2 R59W Neutral Neutral Q17RP2 Q327R Neutral Neutral Q8IY51 V439I Neutral Neutral Q8TD31 K546R Neutral Neutral Q8TD31 E275D Neutral Neutral Q8TD31 S164R Neutral Neutral Q8TD31 Q639H Neutral Neutral Q8TD31 R417W Neutral Neutral Q8TD31 R627Q Neutral Neutral Q8TD31 R103W Neutral Disease Q8TD31 S776C Neutral Neutral Q8TD31 A733V Neutral Neutral Q8TD31 L179Q Neutral Disease Q8TD31 G575C Neutral Neutral Q8TD31 R102Q Neutral Neutral Q8TD31 R417Q Neutral Neutral Q8TD31 A367T Neutral Neutral Q8TD31 R109W Neutral Neutral Q96MD2 S443A Neutral Neutral Q96MD2 I139M Neutral Neutral Q96PL5 A4V Neutral Neutral Q96PL5 G263E Neutral Neutral Q96PL5 C259R Neutral Neutral Q96PL5 H26Y Neutral Neutral O94777 T76S Neutral Neutral P15391 L174V Neutral Neutral P15391 R514H Neutral Neutral P49638 G246R Disease Disease P49638 R221W Disease Disease P49638 R59W Disease Disease P49638 E141K Disease Disease P49638 R192H Disease Disease P49638 T172S Neutral Neutral P49638 H101Q Disease Neutral P49638 A120T Disease Neutral P23942 P216L Disease Disease P23942 L45F Disease Neutral P23942 G266D Disease Disease P23942 G167S Disease Disease P23942 R220W Disease Disease P23942 F211L Disease Disease Q03395 T108M Neutral Neutral Q03395 G118A Neutral Neutral P23942 L185P Disease Disease P23942 G208D Disease Disease P23942 G305D Disease Neutral P23942 Y184S Disease Disease P23942 G167D Disease Disease P23942 R13W Disease Disease Q03395 M271T Neutral Neutral Q03395 A265T Neutral Neutral P23942 C165Y Disease Disease P23942 G68R Disease Disease P23942 P216S Disease Disease Q03395 R242Q Neutral Neutral P23942 R172G Disease Disease P23942 K310R Neutral Neutral P23942 C213R Disease Disease P23942 N244H Disease Disease P23942 L126R Disease Disease P23942 C214S Disease Disease P23942 V268I Disease Neutral P23942 S212G Disease Disease P23942 D157N Disease Disease P23942 P210R Disease Disease P23942 P313L Neutral Neutral Q03395 G75D Neutral Disease P23942 R220Q Disease Disease Q03395 P60T Neutral Neutral Q03395 R16H Neutral Neutral P23942 K153R Disease Neutral P23942 D173V Disease Disease P23942 S212T Disease Disease P23942 P210S Disease Disease P23942 N244K Disease Disease Q03395 R229H Neutral Neutral P24043 L2564P Disease Disease P24043 C862R Disease Disease P24043 C527Y Disease Disease Q14498 A2V Neutral Neutral P41180 R66C Disease Disease P41180 A986S Neutral Neutral P41180 C582Y Disease Disease P41180 Q681H Disease Neutral P41180 A116T Disease Neutral P41180 R795W Disease Disease P41180 R227L Disease Neutral P41180 Q1011E Neutral Neutral P41180 P951T Neutral Neutral P41180 P39A Disease Neutral P41180 G143E Disease Disease P41180 G557E Disease Disease P41180 R227Q Disease Neutral P41180 E297K Disease Disease P41180 F806S Disease Disease P41180 L616V Disease Disease P41180 R185Q Disease Disease P41180 R62M Disease Neutral P41180 T138M Disease Neutral P41180 L174R Disease Disease P41180 R990G Neutral Neutral P41180 C851S Neutral Disease Q9ULV1 M105V Disease Neutral Q9ULV1 M157V Disease Neutral Q6P474 L580R Neutral Neutral Q6P474 L580F Neutral Neutral Q6P474 R144G Neutral Neutral Q6P474 P19L Neutral Neutral Q6P474 M360V Neutral Neutral P30518 Q92R Disease Neutral P30518 N321D Disease Disease P30518 R137L Disease Disease P30518 F287L Disease Disease P30518 R137C Disease Disease P30518 D85N Disease Disease P30518 A163P Disease Disease P30518 P95L Disease Disease P30518 V206D Disease Disease P30559 A16S Neutral Neutral P30518 D191G Disease Neutral P30518 Y205C Disease Disease P30518 C319R Disease Disease P30518 S127F Disease Disease P30518 G122R Disease Disease P30518 A132D Disease Disease P30518 V88M Disease Disease P30518 V277A Disease Disease P30518 I46K Disease Disease P30518 N321K Disease Disease P30518 R137H Disease Disease P30518 I130F Disease Disease P30518 F214S Disease Disease P30518 L44P Disease Disease P30518 L62P Disease Disease P30518 N55D Disease Disease P30518 L83Q Disease Disease P30518 G107E Disease Disease P30518 P217T Disease Disease P30518 G201D Disease Neutral P30518 I209F Disease Disease P30518 R113W Disease Disease P30518 P286S Disease Disease P30518 P173S Disease Disease P30518 L309R Disease Disease P30518 C112R Disease Disease P30518 S315R Disease Disease P30518 R104C Disease Neutral P30518 L94Q Disease Disease P30518 L83P Disease Disease P30518 L219R Disease Disease P30518 R202C Disease Disease P30518 R106C Disease Neutral P30559 A218T Neutral Neutral P30518 A84D Disease Disease P30518 P322H Disease Disease P30518 M272K Disease Disease P30518 A294P Disease Disease P30518 W323S Disease Disease P30518 F105V Disease Disease P30518 S167L Disease Disease P30518 S126F Disease Disease P30518 L289P Disease Disease P30518 P322S Disease Disease P30518 W323R Disease Disease P30518 L81F Disease Disease P30518 S167T Disease Disease P30518 N321Y Disease Disease P30518 N317K Disease Disease P30518 R143P Disease Disease P30518 L43P Disease Disease P30518 L135P Disease Disease P30518 P286R Disease Disease P30518 Q174L Disease Disease P30518 C112Y Disease Disease P30518 Y128S Disease Disease P30518 T207N Disease Disease P30518 R181C Disease Disease P30518 W99R Disease Disease P30518 M123K Disease Disease P30518 L219P Disease Disease P30518 L59P Disease Disease P30518 W164S Disease Disease P30518 G185C Disease Disease P30518 L309P Disease Disease P30518 L53R Disease Disease P30518 L292P Disease Disease P30518 P286L Disease Disease P30518 R203C Disease Disease P30518 T204N Disease Disease P30518 N55H Disease Disease P30518 L282P Disease Disease P30518 H80R Disease Disease Q9NRC6 A3275G Neutral Neutral Q9NRC6 R1345H Neutral Neutral Q9NRC6 R1367T Neutral Neutral Q9NRC6 Q2862R Neutral Neutral Q96PN8 S235L Neutral Disease Q96PN8 A140T Neutral Neutral Q8NG48 R680S Neutral Neutral Q8NG48 A331V Neutral Neutral Q8NG48 M406V Neutral Neutral Q8NG48 E641D Neutral Neutral Q8NG48 I541V Neutral Neutral Q8NG48 I29V Neutral Neutral Q8NG48 S472T Neutral Neutral Q8IUF8 A386T Neutral Neutral O00311 T472I Neutral Neutral O00311 Q23P Neutral Neutral O00311 S498A Neutral Neutral O00311 K441R Neutral Neutral O00311 G112W Neutral Disease O00311 F162L Neutral Neutral O00311 E209D Neutral Neutral O00311 I99V Neutral Neutral O00311 I208M Neutral Neutral Q86VM9 H440R Neutral Neutral Q86VM9 A368T Neutral Neutral Q96JG9 T3636A Neutral Neutral Q96JG9 P1420L Neutral Neutral Q96JG9 A2710T Neutral Neutral Q96JG9 E3630Q Neutral Neutral Q96JG9 R2129K Neutral Neutral Q96JG9 L2670Q Neutral Neutral Q96JG9 G2358R Neutral Neutral Q96JG9 D2749V Neutral Neutral Q96JG9 H2848R Neutral Neutral Q96JG9 K1162E Neutral Neutral Q96JG9 R366S Neutral Neutral Q00839 F711L Neutral Neutral O95154 N215D Neutral Neutral O43488 Q157H Neutral Neutral O43488 C214Y Neutral Disease O95154 T323A Neutral Neutral O43488 A142T Neutral Neutral O95154 V138M Neutral Disease P07492 S4R Neutral Neutral Q01726 D84E Neutral Disease Q01726 R163Q Neutral Disease Q01726 A171S Neutral Neutral Q01726 V92M Neutral Neutral Q01726 D294H Neutral Disease Q01726 V156L Neutral Disease Q01726 G104S Neutral Disease Q01726 G89R Neutral Disease Q01726 T95M Neutral Neutral Q01726 F196L Neutral Disease Q01726 I155T Neutral Disease Q01726 R151C Neutral Disease Q01726 I120T Neutral Neutral Q01726 V60L Neutral Neutral Q01726 A166G Neutral Neutral Q01726 R67Q Neutral Disease Q01726 R160W Neutral Disease Q01726 R162P Neutral Disease Q5VVY1 S148P Neutral Neutral Q14249 L12S Neutral Neutral P25063 A57V Neutral Neutral P25063 T44S Neutral Neutral Q9NP85 G92C Disease Neutral Q9NP85 P20L Disease Neutral Q9NP85 R291W Disease Disease Q9NP85 R138Q Disease Disease Q9NP85 D160G Disease Disease Q9NP85 V180M Disease Disease Q5JNZ3 R486C Neutral Neutral Q5JNZ3 K511Q Neutral Neutral Q9P0V3 A197T Neutral Neutral Q9P0V3 M155T Neutral Neutral Q9NQG7 V552M Neutral Neutral Q9NQG7 Q625H Neutral Neutral Q9NQG7 L443V Neutral Neutral Q9NQG7 H606Y Neutral Disease Q9NQG7 E229G Neutral Neutral Q8TF72 L146H Neutral Neutral Q8TF72 A278G Neutral Neutral Q8TF72 L1289P Neutral Disease Q8TF72 A468P Neutral Neutral Q5T1B1 E144G Neutral Neutral P62424 A24V Neutral Neutral O96020 N387S Neutral Neutral A7MBM2 G1145S Neutral Neutral A7MBM2 C56S Neutral Neutral A7MBM2 P47A Neutral Neutral A7MBM2 G388E Neutral Neutral A7MBM2 R1247W Neutral Neutral O94885 P298Q Neutral Neutral O94885 Q884R Neutral Neutral O60337 P622L Neutral Neutral Q6ZSC3 I259V Neutral Neutral Q8N5B7 C75R Neutral Neutral Q9HC35 V382I Neutral Neutral Q9HC35 E283K Neutral Disease Q32P44 Q620K Neutral Disease Q9HC35 S978L Neutral Neutral Q9HC35 K398R Neutral Neutral Q7Z4Q2 R302S Neutral Neutral P37173 R528C Disease Disease P37173 T315M Disease Neutral P37173 Y336N Disease Disease P37173 M36V Neutral Neutral P37173 N435S Disease Neutral P37173 V447A Disease Disease P37173 R460C Disease Disease P37173 M373I Neutral Neutral P37173 R460H Disease Disease P37173 L452M Disease Neutral P37173 R537C Disease Disease P37173 R528H Disease Disease P37173 S449F Disease Disease P37173 V439A Neutral Disease P37173 G357W Disease Disease P37173 V387M Disease Neutral P37173 L308P Disease Disease P37173 E526Q Disease Neutral P37173 A355P Disease Disease P37173 V191I Neutral Neutral Q9UMW8 T169M Neutral Neutral O43196 P29S Neutral Neutral O43196 L377F Neutral Disease O43196 P786S Neutral Neutral O43196 V206F Neutral Neutral O43196 L85F Neutral Neutral O43196 R351G Neutral Neutral O43196 Y202C Neutral Disease Q5T4J0 P316L Neutral Disease P51159 L130P Disease Disease P51149 K32E Neutral Neutral P51149 V162M Disease Disease P01112 G12V Disease Disease P51159 L84F Neutral Neutral P01116 G12C Disease Disease P51149 N161T Disease Disease P01116 P34R Disease Disease P01116 G12R Disease Disease P51159 A152P Disease Disease P01116 G12D Disease Disease Q9H0T7 L191P Neutral Disease P51149 K157N Disease Disease P01116 G12V Disease Disease P01111 G13R Disease Disease Q96AX2 A188P Neutral Disease P01111 Q61R Disease Disease P01112 G13C Disease Disease P51159 T85P Neutral Disease Q9NP72 A198T Neutral Neutral P61106 A4T Neutral Neutral P01116 Q61H Disease Disease P51159 W73G Disease Disease P01112 Q61L Disease Disease P01116 T58I Disease Disease P01116 G12S Disease Disease P01111 G12C Disease Disease P01116 G13D Disease Disease P51149 L129F Disease Disease P51159 T62S Neutral Disease P01112 G12S Disease Disease P01116 G60R Disease Disease P01116 V14I Disease Disease P01112 G12A Disease Disease P62070 Q72L Disease Disease P01112 G13D Disease Disease P01116 A59T Disease Disease Q9H628 M163V Neutral Neutral Q969F2 T257K Neutral Disease Q8WYA1 N340S Neutral Neutral Q8WYA1 A574V Neutral Neutral P04004 R268Q Neutral Disease P04004 A122S Neutral Neutral P04004 T400M Neutral Neutral O00115 R314L Neutral Disease Q5VWN6 R1075P Neutral Neutral Q5VWN6 V1679A Neutral Neutral Q5VWN6 S2404N Neutral Neutral O60513 Q116E Neutral Neutral P14784 S83F Neutral Neutral P14784 D391E Neutral Neutral P14780 F571V Neutral Disease P14780 R668Q Neutral Neutral P14780 N38S Neutral Neutral P14780 R279Q Neutral Neutral P14780 A20V Neutral Neutral P14780 P574R Neutral Neutral P14780 E82K Neutral Disease P14780 N127K Neutral Disease P14780 R239H Neutral Neutral Q9BW71 G521W Neutral Neutral Q92826 T41M Neutral Neutral P00734 P386T Neutral Neutral P00734 T165M Neutral Neutral Q96RT1 K1207E Neutral Disease Q96RT1 S274L Neutral Neutral Q96RT1 S1112L Neutral Neutral Q96RT1 K746E Neutral Neutral Q99500 R243Q Neutral Disease Q08AI6 A194T Neutral Neutral Q12834 R479Q Neutral Neutral Q12834 V402M Neutral Neutral P35240 N220Y Disease Disease P35240 L535P Disease Disease P35240 R351H Neutral Disease P35240 Q538P Disease Disease P35240 I273F Disease Disease P35240 L360P Disease Disease P35240 K364I Disease Neutral P35240 F62S Disease Disease P35241 D490N Neutral Neutral P35241 K328E Neutral Neutral P15311 A494P Neutral Neutral P35241 D578N Disease Neutral P35240 E106G Disease Neutral P35240 T352M Disease Neutral P35240 L234R Disease Disease P15311 R180C Neutral Disease P15311 L532V Neutral Neutral Q8WVK2 S114F Neutral Neutral Q8WVK2 T81I Neutral Neutral Q9NWS1 V400M Neutral Neutral Q6UDR6 G73S Neutral Disease Q8NHW6 P7L Neutral Neutral P11171 V214I Neutral Neutral Q6EMK4 E384A Neutral Neutral Q9H993 P77R Neutral Disease Q9H195 A698V Neutral Neutral Q9H195 H877Y Neutral Neutral P23368 P114L Neutral Disease P23409 A90D Disease Disease P23409 A112S Disease Disease Q9UEE5 E362K Neutral Neutral Q9UEE5 M167T Neutral Neutral Q9UEE5 E126D Neutral Neutral Q9UEE5 E286Q Neutral Neutral Q9BWT7 R289Q Neutral Neutral Q15776 P163L Neutral Neutral Q9BRR0 R3T Neutral Neutral Q16670 R220S Neutral Neutral Q9BRR0 F34L Neutral Neutral Q9BRR0 K200E Neutral Neutral Q9BRR0 H246Q Neutral Neutral Q9BRR0 K200T Neutral Neutral Q9BRR0 G33V Neutral Neutral P17029 V26A Neutral Disease Q9BRR0 V189M Neutral Neutral Q6NSZ9 P325A Neutral Neutral Q8IXZ2 M6I Neutral Neutral Q8IXZ2 E151D Neutral Neutral Q8IXZ2 G452S Neutral Neutral Q8IXZ2 F149Y Neutral Neutral Q8IXZ2 S399G Neutral Neutral Q9BR11 R101Q Neutral Neutral Q9Y3I1 M115I Neutral Neutral P48307 V102A Neutral Neutral Q86YA3 T978I Neutral Neutral Q86YA3 N410S Neutral Neutral Q86YA3 E451G Neutral Neutral Q9NPH0 M316V Neutral Neutral Q9UI10 Y489H Disease Disease Q9UI10 R306G Neutral Disease Q9UI10 R374C Disease Disease Q9UI10 R357Q Disease Neutral Q9UI10 C465R Disease Neutral Q9UI10 A228V Disease Disease O43681 N332S Neutral Neutral Q8N6Q3 A3P Neutral Neutral Q8N6Q3 L119F Neutral Neutral Q8N6Q3 F379S Neutral Neutral Q8N6Q3 R323Q Neutral Neutral Q8N6Q3 L251I Neutral Neutral Q8N6Q3 A348T Neutral Neutral Q9UFB7 A9T Neutral Neutral Q8TBC5 G379E Neutral Neutral Q13596 D466N Neutral Neutral Q8WWB7 I223V Neutral Neutral Q8WWB7 V94I Neutral Neutral Q8WWB7 P203S Neutral Neutral Q2M243 T353M Neutral Neutral Q2M243 M267T Neutral Neutral Q2M243 Q54E Neutral Neutral Q07864 E1399Q Neutral Neutral Q07864 A252V Neutral Neutral Q07864 F695I Neutral Disease Q07864 Y1395C Neutral Neutral Q07864 A1712V Neutral Neutral Q07864 K1857R Neutral Neutral Q07864 N336S Neutral Disease Q07864 N1396S Neutral Neutral Q07864 R1382C Neutral Neutral Q07864 C1935Y Neutral Neutral Q07864 R260Q Neutral Neutral Q07864 P99L Neutral Neutral Q07864 R2165H Neutral Disease Q07864 E1577A Neutral Neutral Q07864 A2040V Neutral Neutral Q9H244 R265W Disease Neutral Q9H244 R256Q Disease Neutral Q9BPV8 M158T Neutral Disease Q15751 G3517R Neutral Disease Q15751 L1278F Neutral Neutral Q15751 T1995A Neutral Neutral Q15751 A1696G Neutral Neutral Q15751 D3722E Neutral Neutral Q15751 S3152F Neutral Neutral Q15751 V2220I Neutral Neutral Q15751 S1572A Neutral Neutral Q15751 A2816T Neutral Neutral Q15751 G1411V Neutral Neutral Q15751 H1447N Neutral Disease Q15751 L1088F Neutral Neutral Q9BQD3 P157A Neutral Neutral P21953 R183P Disease Disease P21953 H206R Disease Disease P21953 G278S Disease Disease P15169 G178D Disease Disease Q92968 I326T Disease Neutral Q9UI32 L581P Neutral Neutral Q6UWP7 I290V Neutral Neutral Q96CV9 R545Q Disease Neutral Q96CV9 S308P Neutral Disease Q96CV9 H26D Disease Neutral Q96CV9 E103D Disease Neutral Q96CV9 H486R Disease Neutral Q96CV9 P201S Neutral Neutral Q96CV9 E322K Neutral Neutral Q96CV9 E50K Disease Neutral Q96CV9 S216R Neutral Neutral Q96CV9 M98K Neutral Neutral Q96CV9 T357P Neutral Neutral Q9UMD9 T210M Neutral Disease Q9UMD9 M231I Neutral Neutral Q9UMD9 M703V Neutral Neutral Q9UMD9 R1303Q Disease Neutral Q9UMD9 G633D Disease Disease Q9UMD9 G428S Neutral Neutral Q9UMD9 G627V Disease Disease Q9UMD9 D1370G Neutral Neutral Q9UMD9 M238T Neutral Neutral Q9UMD9 S265C Disease Neutral Q6P995 V304I Neutral Neutral Q9HC97 R125S Neutral Neutral Q9HC97 A25T Neutral Neutral Q9HC97 T108M Neutral Disease Q9HC97 S294R Neutral Neutral Q9HC97 T253M Neutral Neutral Q9HC97 V76M Neutral Neutral Q9HC97 V29I Neutral Neutral P24394 V579I Neutral Neutral P24394 S436L Neutral Neutral P24394 S503P Neutral Neutral P24394 S786P Neutral Neutral P24394 P675S Neutral Neutral P24394 Q576R Neutral Neutral P24394 S387L Neutral Neutral P24394 I75V Neutral Neutral P24394 C431R Neutral Neutral P24394 E400A Neutral Neutral P24394 S752A Neutral Neutral O15143 K37N Neutral Disease Q9H2S5 A304E Neutral Neutral Q9H2S5 S203P Neutral Neutral Q9H2S5 D268N Neutral Disease Q9H2S5 A245T Neutral Disease Q99797 R340Q Neutral Neutral Q99797 A137V Neutral Disease Q99797 R453H Neutral Disease Q99797 S488G Neutral Neutral Q6UWV6 L4P Neutral Disease Q6UWR7 S419G Neutral Neutral P04141 I117T Neutral Neutral P04141 T115I Neutral Neutral Q8TAZ6 I122T Neutral Neutral Q7Z304 N294S Neutral Neutral Q56NI9 W539G Disease Disease Q56NI9 A80V Neutral Neutral P43628 P229L Neutral Neutral P43626 P37R Neutral Disease P43628 H34Q Neutral Neutral P43627 R37P Neutral Neutral P43626 H203R Neutral Neutral P43626 R266C Neutral Disease P43628 V9A Neutral Neutral P43628 A304T Neutral Disease P43628 R242I Neutral Disease P43626 P135L Neutral Disease P43628 H71R Neutral Neutral P43628 Q56E Neutral Neutral P43626 P175T Neutral Neutral P43626 K237E Neutral Neutral P43626 V5F Neutral Disease P43628 L32R Neutral Disease P43628 R318H Neutral Disease P43626 D184N Neutral Neutral P10643 R521S Disease Disease P10643 R220Q Disease Neutral P13671 S470F Neutral Neutral P10643 R687H Disease Neutral P10643 S389T Neutral Neutral P10643 T587P Neutral Neutral P13671 K397E Neutral Neutral P13671 A119E Neutral Neutral P10643 K420Q Neutral Disease P10643 E682Q Disease Neutral P10643 G379R Disease Disease Q9BTX3 D82Y Neutral Neutral Q8IYM0 E553Q Neutral Neutral Q8IYM0 V397M Neutral Neutral Q6P158 S433G Neutral Neutral Q6ZN11 I68M Neutral Neutral Q9BV29 K2I Neutral Neutral Q96KR7 P154L Neutral Neutral Q3MJ13 L819F Neutral Neutral Q3MJ13 S833A Neutral Neutral Q6DN14 R612K Neutral Neutral Q15050 R191L Neutral Disease P51681 L55Q Neutral Neutral P49238 V147I Neutral Neutral P51686 M284V Neutral Neutral P49682 A363T Neutral Neutral P25024 M31R Neutral Neutral P51679 L130V Neutral Neutral P49238 V249I Neutral Neutral P51677 G21D Neutral Neutral P49238 T57A Neutral Neutral P49238 T280M Neutral Neutral P51677 C218S Neutral Neutral P25025 R80C Neutral Neutral P51681 C20S Neutral Disease P51681 S215L Neutral Disease P49682 R292Q Neutral Neutral P51681 A29S Neutral Neutral P51681 A335V Neutral Neutral P51681 I12L Neutral Disease P25024 R335C Neutral Disease P51681 Y339F Neutral Neutral O00590 Y373S Neutral Neutral P51681 R223Q Neutral Disease P25024 A306T Neutral Neutral P25024 S342L Neutral Disease P25024 S276T Neutral Neutral P51681 I42F Neutral Disease P25024 R71C Neutral Neutral P51679 C178S Neutral Neutral P51681 R60S Neutral Neutral P51681 G301V Neutral Disease P49238 V122I Neutral Neutral P51681 A73V Neutral Neutral P25024 M268L Neutral Neutral P51686 I92V Neutral Neutral Q92901 P291L Neutral Neutral Q5JR12 L213F Neutral Neutral Q5JR12 V236I Neutral Neutral Q8N6Y0 M439V Neutral Neutral Q8N6Y0 V525M Neutral Neutral Q9H892 M468L Neutral Neutral Q9H892 L73M Neutral Neutral P54725 T200M Neutral Neutral P54725 T131A Neutral Neutral P54725 R179Q Neutral Neutral P54727 A249V Neutral Neutral Q9NYW5 F7S Neutral Neutral P59533 A49P Neutral Disease Q9NYW5 R3Q Neutral Neutral Q9NYW4 Y167C Neutral Disease Q9NYW5 V96L Neutral Neutral Q9NYW7 R206W Neutral Disease P59538 R35W Neutral Neutral P59538 Q217E Neutral Neutral P59538 M162L Neutral Neutral Q9NYW4 R213Q Neutral Disease P59533 I296V Neutral Neutral Q9NYW4 S26I Neutral Disease Q9NYW3 T263S Neutral Neutral Q9NYW7 R111H Neutral Disease P59544 Y203C Neutral Neutral Q9NYW5 S171N Neutral Neutral P59538 V240I Neutral Neutral P59538 A227V Neutral Disease Q9NYW3 M304I Neutral Neutral Q9NYW1 V187A Neutral Neutral Q9NYW0 M156T Neutral Neutral Q9NYW5 T74M Neutral Neutral Q9NYW4 P113L Neutral Neutral P59533 A262V Neutral Disease Q9NYW2 M308V Neutral Neutral Q96M63 R274H Neutral Neutral Q96M63 P413L Neutral Neutral Q7Z695 P626L Neutral Neutral Q7Z695 S307P Neutral Disease Q7Z695 V418M Neutral Neutral Q7Z695 P622L Neutral Neutral Q7Z695 V418L Neutral Neutral Q01658 E171D Neutral Neutral Q96SI1 G64S Neutral Disease P43403 R465H Disease Disease P43403 S518R Disease Disease P43405 R45H Neutral Neutral Q14397 G256S Neutral Disease Q14397 E77G Neutral Disease Q14397 P446L Neutral Neutral Q14397 R540Q Neutral Neutral Q9BX59 G151R Neutral Neutral Q96NW4 P761R Neutral Neutral Q96NW4 S657G Neutral Neutral Q03518 V518I Neutral Neutral Q03519 A513S Neutral Disease Q03518 G419C Neutral Neutral Q03518 G17R Neutral Neutral Q03519 V379I Neutral Neutral Q03519 T665A Neutral Disease Q03518 D637G Neutral Neutral Q03518 V458L Neutral Disease Q03519 M577V Neutral Neutral Q03518 I333V Neutral Neutral Q03518 P7S Neutral Neutral Q03519 A565T Neutral Neutral Q03519 R56K Neutral Neutral Q03519 R651C Neutral Disease Q03519 A374T Neutral Disease Q03519 V467I Neutral Neutral Q03518 A370V Neutral Neutral Q03518 R659Q Disease Disease Q03518 R648Q Neutral Disease P00367 R318K Disease Neutral P00367 R322C Disease Disease P00367 S498L Disease Neutral P00367 R274C Disease Disease P00367 Y319C Disease Disease P00367 H507Y Disease Disease P00367 E349A Disease Neutral P00367 S270C Disease Disease P00367 S501P Disease Disease P00367 G499D Disease Disease P00367 R318T Disease Disease P00367 G499S Disease Disease P00367 R322H Disease Disease Q13489 K260R Neutral Neutral Q13489 R401K Neutral Neutral Q13490 A506V Neutral Neutral Q13490 M453V Neutral Neutral Q13490 P549S Neutral Neutral Q8WUY1 E93Q Neutral Disease Q14943 R166H Neutral Neutral Q15397 V297L Neutral Neutral Q15397 R289P Neutral Neutral Q9P2A4 R44Q Neutral Neutral Q14114 E46D Neutral Neutral Q14114 W466C Neutral Disease Q14114 S653T Neutral Disease Q14114 Q607R Neutral Disease Q14114 R952Q Neutral Neutral Q14114 I611L Neutral Disease Q14114 V453M Neutral Disease A2RUC4 S50G Neutral Neutral A0AVT1 A224T Neutral Neutral Q9H816 R46L Neutral Disease Q9H816 D462N Neutral Neutral Q9H816 H61Y Neutral Disease Q8IYW5 P401Q Neutral Neutral Q8IYW5 K387R Neutral Neutral Q14587 T175M Neutral Neutral Q9H0B3 S285T Neutral Neutral Q9H0B3 Y648F Neutral Neutral Q9H0B3 L44P Neutral Neutral Q9H0B3 M359T Neutral Neutral Q9H0B3 L235V Neutral Neutral Q9H0B3 P823R Neutral Neutral Q9H0B3 P908H Neutral Neutral Q0P611 T7S Neutral Neutral Q0P611 T7A Neutral Neutral Q0P611 I117V Neutral Neutral P49959 R572Q Disease Neutral P49959 R305W Disease Disease P49959 S104C Disease Disease P49959 D468G Neutral Neutral P49959 R503H Disease Neutral P49959 M157V Neutral Neutral P49959 N117S Disease Disease P49959 M698V Neutral Neutral O00476 G182R Neutral Disease O00476 A81T Neutral Disease Q8N7Z5 R758G Neutral Neutral Q8N7Z5 D1609E Neutral Neutral Q8N7Z5 R1777K Neutral Neutral Q8N7Z5 D702N Neutral Neutral Q8IVJ8 H107Y Neutral Disease Q5TAH2 A505G Neutral Neutral Q5TAH2 T481M Neutral Neutral Q5TAH2 R934S Neutral Neutral Q9BT51 L11V Neutral Neutral Q9UNZ2 D290N Neutral Neutral Q96B70 R477P Neutral Neutral Q96B70 H131R Neutral Neutral P23786 R631C Disease Disease P23786 P227L Disease Disease P23786 D213G Disease Disease P23786 R296Q Disease Disease P23786 P50H Disease Disease P23786 Y628S Disease Disease P23786 P604S Disease Disease P23786 D553N Disease Disease P23786 E174K Disease Disease P23786 Y210D Disease Disease P23786 F383Y Disease Neutral P23786 M214T Disease Disease P23786 G600R Disease Disease P23786 S588C Neutral Disease P23786 G549D Disease Disease P23786 R151Q Disease Disease P23786 Q550R Disease Neutral P23786 R503C Disease Disease P23786 Y479F Disease Neutral P23786 V368I Neutral Neutral P23786 F448L Disease Disease P23786 S113L Disease Disease P23786 F352C Neutral Disease P23786 M647V Neutral Neutral O60494 P1297L Disease Disease O95197 A6E Neutral Neutral Q5T7B8 D50E Neutral Disease Q5T7B8 M140V Neutral Neutral Q15822 A125T Neutral Neutral Q15822 I279N Disease Disease Q15822 T22I Neutral Neutral O75352 G73E Disease Disease O75352 L119P Disease Disease O75352 L74S Disease Disease Q8IWJ2 R1197G Neutral Neutral Q96NY7 D632G Neutral Disease Q9C0F1 G147S Neutral Neutral Q6P4F1 Y268H Neutral Neutral Q6P4F1 L59F Neutral Neutral Q6P4F1 R371P Neutral Disease Q6P4F1 L368V Neutral Neutral Q14679 L364P Neutral Disease Q14679 S524G Neutral Neutral Q14679 N17S Neutral Neutral Q14679 E34Q Neutral Neutral Q14679 A852S Neutral Neutral Q14679 R418H Neutral Disease Q14679 G518S Neutral Neutral P80303 Q338E Neutral Neutral Q8N5M1 W94G Disease Disease Q96SQ7 P150L Neutral Neutral P22301 G15R Disease Disease Q9BZ71 A80T Neutral Neutral Q9HB63 Y205H Neutral Neutral P51788 G715E Disease Neutral Q8N6C7 R73S Neutral Neutral Q8N6C7 H91Q Neutral Neutral Q9H720 T2P Neutral Neutral Q9H720 N689H Neutral Neutral Q6UQ28 S142P Neutral Neutral Q6UX73 Y363H Neutral Neutral Q6UX73 L296S Neutral Neutral Q96FE7 T251S Neutral Neutral Q96ET8 D12A Neutral Neutral Q14197 L77F Neutral Neutral Q14197 R8P Neutral Disease P46091 I307V Neutral Neutral Q96GQ7 G766S Neutral Neutral Q9UPZ3 L417M Neutral Neutral Q96D15 R250W Neutral Neutral O43852 R4Q Neutral Neutral Q5T653 S300F Neutral Neutral P05156 A300T Neutral Neutral P05156 H418L Disease Disease P05156 G243D Disease Disease Q9Y232 A60G Neutral Neutral Q9Y232 T2A Neutral Neutral Q9Y232 V48A Neutral Neutral Q9Y232 S9P Neutral Neutral Q9Y239 E266K Neutral Disease O60522 T398A Neutral Neutral O60522 R192Q Neutral Neutral O60522 Q1014E Neutral Neutral O60664 I56V Neutral Neutral O60664 A275V Neutral Neutral Q5VTY9 N450S Disease Neutral Q5VTY9 G448E Disease Disease Q5VTY9 S182N Neutral Disease Q9Y5X4 G88V Disease Disease Q9Y5X4 L353V Disease Disease Q9Y5X4 L263P Disease Disease Q9Y5X4 M407K Disease Disease Q9Y5X4 A256E Disease Disease Q9Y5X4 G56R Disease Disease Q9Y5X4 V302I Neutral Neutral Q9Y5X4 V232I Neutral Neutral Q9Y5X4 R76Q Disease Neutral Q9Y5X4 M163T Neutral Neutral Q9Y5X4 L336P Disease Disease Q9Y5X4 E140G Neutral Neutral Q9Y5X4 W234S Disease Disease Q9Y5X4 E121K Disease Neutral Q9Y5X4 R104W Disease Disease Q9Y5X4 R385P Disease Disease Q9Y5X4 R309G Disease Disease Q9Y5X4 R311Q Disease Disease Q9Y5X4 R97H Disease Disease Q9Y5X4 R76W Disease Disease P30304 R182W Neutral Neutral P30304 S88F Neutral Neutral P30304 R182G Neutral Neutral P30305 E548K Neutral Disease P41250 G580R Disease Disease P41250 E125G Disease Disease P41250 G294R Disease Disease P41250 L183P Disease Disease O14525 G1270R Neutral Neutral P18440 R117T Neutral Neutral P18440 T207I Neutral Neutral P11245 Y208H Neutral Disease P11245 G286E Neutral Neutral P11245 T193M Neutral Neutral P18440 D251V Neutral Neutral P18440 I263V Neutral Neutral P18440 R187Q Neutral Neutral P11245 I114T Neutral Disease P11245 K282T Neutral Neutral P11245 R64Q Neutral Disease P11245 Q145P Neutral Disease P18440 M205V Neutral Neutral P11245 R197Q Neutral Neutral P18440 S214A Neutral Neutral P11245 L137F Neutral Disease P11245 P228L Neutral Neutral P18440 V149I Neutral Neutral P11245 K268R Neutral Neutral P11245 L24I Neutral Disease P11245 R64W Neutral Disease P18440 E261K Neutral Neutral P18440 R64W Neutral Disease P11245 D122N Neutral Disease O60502 E602K Neutral Neutral O60502 G46E Neutral Neutral Q9H8M2 A293T Neutral Neutral Q9H8M2 A170T Neutral Neutral Q27J81 P1096S Neutral Neutral Q27J81 T1135M Neutral Neutral Q9BVP2 M367V Neutral Neutral Q9BVP2 Q39R Neutral Neutral A4QPB2 T61M Neutral Neutral P04035 I638V Neutral Neutral Q96HA8 I32V Neutral Neutral Q96HA8 R134C Neutral Neutral Q96HA8 F116I Neutral Disease Q96HA8 N93S Neutral Neutral Q8HWS3 E6K Neutral Neutral Q8HWS3 T688A Neutral Neutral Q8HWS3 S743N Neutral Neutral Q96BT3 P115L Neutral Neutral O60812 V258D Neutral Neutral P20138 I242L Neutral Neutral P20138 V294L Neutral Neutral P20138 R202W Neutral Disease P20138 F243L Neutral Disease P20138 R69G Neutral Disease Q8N9C0 L130R Neutral Disease Q8N9C0 M559V Neutral Neutral Q8N9C0 S503I Neutral Neutral Q8N9C0 A94P Neutral Neutral Q8N9C0 R472Q Neutral Neutral Q8N9C0 V414I Neutral Neutral Q8N9C0 L677F Neutral Neutral P30154 G15A Disease Neutral P30154 V545A Disease Disease P30154 V448A Disease Neutral P30154 S365P Disease Disease P30154 D504G Disease Disease P30154 K343E Disease Neutral P30154 G8R Disease Neutral P30154 L101P Disease Disease P30154 L499I Disease Neutral P30154 V500G Disease Neutral P30154 G90D Disease Neutral P30154 V498E Disease Disease P30154 P65S Disease Disease Q96JL9 A251E Neutral Disease Q16890 R62K Neutral Neutral P13489 P170L Neutral Disease Q8NI51 Q525E Neutral Neutral Q8NI51 A177T Neutral Neutral Q8NI51 E50Q Neutral Neutral P22413 L91P Disease Disease P22413 N179S Neutral Disease P22413 Y268H Neutral Disease P22413 R886T Neutral Neutral O14638 V620M Neutral Neutral P22413 Y371F Disease Neutral O14638 S786N Neutral Disease P22413 K173Q Neutral Neutral P22413 R774C Disease Neutral P22413 T779P Neutral Disease P22413 L579F Disease Neutral P22413 G342V Disease Disease P22413 S287F Disease Neutral Q9P2P6 Y3383C Neutral Neutral Q9P2P6 D70N Neutral Neutral Q9P2P6 R2591H Neutral Neutral Q9P2P6 N3297D Neutral Neutral Q9P2P6 R1124C Neutral Neutral Q9P2P6 Y3321C Neutral Neutral Q9P2P6 A2119V Neutral Neutral Q9P2P6 P1634L Neutral Neutral Q9P2P6 T2769I Neutral Neutral Q9P2P6 P2783S Neutral Neutral Q9P2P6 R2929G Neutral Neutral Q9Y6L6 D462G Neutral Disease Q9Y6L6 D241N Neutral Neutral Q9Y6L6 N130D Neutral Neutral Q9Y6L6 N432D Neutral Disease Q9Y6L6 R152K Neutral Neutral Q9Y6L6 E667G Neutral Neutral Q8NE63 G421S Neutral Neutral Q8NE63 A106T Neutral Neutral Q8NE63 R481C Neutral Neutral Q8NE63 R302Q Neutral Disease Q8NE63 S406R Neutral Neutral Q8NE63 A386T Neutral Neutral Q8NE63 V171M Neutral Disease Q8NE63 T381M Neutral Neutral O00204 L51S Neutral Neutral O00204 M301I Neutral Disease O00204 V240I Neutral Neutral O00204 P345L Neutral Neutral Q6ZVN8 W191C Disease Disease Q6ZVN8 G320V Disease Disease Q6ZVN8 A168D Disease Disease Q6ZVN8 G250V Disease Disease Q6ZVN8 R288W Disease Disease Q6ZVN8 S205R Disease Disease Q6ZVN8 C321W Disease Disease Q6ZVN8 C80R Disease Disease Q6ZVN8 G99R Disease Disease Q6ZVN8 S85P Disease Neutral Q6ZVN8 D172E Disease Disease Q6ZVN8 F170S Disease Disease Q6ZVN8 I222N Disease Disease Q6ZVN8 L101P Disease Disease Q01151 R182Q Neutral Neutral P07332 M323V Neutral Neutral P07332 R85C Neutral Neutral P07332 R246Q Neutral Neutral Q8NI77 I735V Neutral Neutral Q96L12 L8F Neutral Neutral Q96L12 V274I Neutral Neutral Q96L12 D248G Neutral Disease Q9NUM3 E64D Neutral Neutral Q9NUM3 R285C Neutral Neutral Q9NUM3 M221T Neutral Neutral Q8N6R0 M105V Neutral Neutral Q8N6R0 M359I Neutral Neutral Q5TID7 F172S Neutral Disease Q9UNA0 R614H Neutral Disease Q9UNA0 P692L Neutral Disease Q9UNA0 A138G Neutral Neutral Q8N9H8 Q220R Neutral Neutral Q8IY82 C766R Neutral Neutral Q8IY82 L433P Neutral Neutral Q8IY82 N581K Neutral Neutral Q8IY82 S186C Neutral Neutral Q9NV66 H632R Neutral Neutral Q9NV66 D671N Neutral Disease Q9NV66 G462V Neutral Disease Q86XK3 D81G Neutral Neutral Q01968 Y513C Disease Disease Q01968 Y479C Disease Disease Q01968 R318C Disease Disease Q01968 H375Y Disease Disease Q01968 V508D Disease Disease Q01968 A797P Disease Disease Q01968 R337P Disease Disease Q01968 I533S Disease Disease Q01968 H524R Disease Disease Q01968 R500Q Disease Disease Q01968 V372G Disease Disease Q01968 I768N Disease Disease Q01968 H524Q Disease Disease Q01968 R500G Disease Disease Q01968 N424D Disease Disease Q01968 G421E Disease Disease Q01968 C498Y Disease Disease Q01968 F463S Disease Disease Q01968 G357E Disease Disease Q01968 D451G Disease Disease Q01968 S522R Disease Disease Q01968 P526L Disease Disease Q8TEB1 R207H Neutral Neutral Q9P2T0 R267Q Neutral Neutral Q9P2T0 H297Y Neutral Neutral Q9P2T0 R202I Neutral Disease Q9P2T0 D353N Neutral Neutral O00567 V576A Neutral Neutral O00567 I121V Neutral Neutral O00567 M475T Neutral Neutral P07814 A296P Neutral Neutral P07814 I1043V Neutral Neutral P07814 H334Q Neutral Neutral P07814 E308D Neutral Neutral P07814 P893H Neutral Neutral P07814 T1399N Neutral Neutral P07814 S1107F Neutral Neutral P45381 P183H Disease Neutral P45381 H244R Disease Disease P45381 I143T Disease Neutral P45381 R168H Disease Neutral P45381 V186F Disease Disease P45381 P280S Disease Disease P45381 F295S Disease Disease P45381 C152Y Disease Neutral P45381 A305E Disease Neutral P45381 D249V Disease Disease P45381 M195R Disease Disease P45381 E285A Disease Disease P45381 D114Y Disease Disease P45381 I16T Disease Neutral P45381 P280L Disease Disease P45381 D114E Disease Disease P45381 G27R Disease Disease P45381 D68A Disease Disease P45381 A287T Disease Disease P45381 R168C Disease Disease P45381 Y231C Disease Neutral P45381 E24G Disease Disease P45381 H21P Disease Disease P45381 C152W Disease Neutral P45381 P181T Disease Disease P45381 C152R Disease Disease P45381 G123E Disease Disease P45381 C310G Neutral Neutral P45381 G274R Disease Disease P45381 A57T Disease Disease Q9BWN1 P359L Neutral Neutral Q7L590 K669R Neutral Neutral Q7L590 T541S Neutral Neutral Q7L590 K134R Neutral Neutral Q14990 S216N Neutral Neutral P12104 A55T Neutral Neutral Q9BV38 L213F Neutral Neutral Q9BV38 A172T Neutral Neutral Q9BV38 V264I Neutral Neutral P56645 S1081C Neutral Neutral P56645 A1007T Neutral Neutral P56645 V639G Neutral Disease P56645 P827L Neutral Neutral P56645 T1010I Neutral Neutral P56645 M1028T Neutral Neutral P56645 P856A Neutral Neutral P56645 H1149R Neutral Neutral Q9H4B6 A185D Disease Disease O95905 R281G Neutral Neutral Q5BJF6 T710S Neutral Neutral P22694 R106Q Neutral Neutral P17612 R46Q Neutral Neutral P17612 L41V Neutral Disease P17612 S264C Neutral Neutral P22612 H268D Neutral Neutral P22612 I251N Neutral Neutral Q6ZV23 I287V Neutral Neutral P29120 N221D Neutral Disease P29120 G483R Disease Neutral P29120 R80Q Neutral Neutral P29120 Q665E Neutral Neutral P29120 S690T Neutral Neutral P59817 N136S Neutral Neutral P59817 N246S Neutral Neutral P59817 K71N Neutral Neutral P59817 L486F Neutral Neutral P59817 R488S Neutral Neutral Q86YH2 V522G Neutral Neutral P59817 G249A Neutral Neutral P59817 N278D Neutral Neutral Q86YH2 A256E Neutral Neutral P59817 Y137S Neutral Neutral P59817 L276F Neutral Neutral Q05086 G290V Neutral Neutral Q05086 C44Y Neutral Disease Q05086 S372P Neutral Disease Q05086 R62H Neutral Neutral Q05086 A201T Neutral Neutral Q9H336 A286S Neutral Neutral Q9H0B8 T322S Neutral Neutral Q9H0B8 S105G Neutral Neutral Q9UHQ9 N44S Neutral Neutral Q695T7 L242P Disease Disease Q96N87 L478P Neutral Disease Q96N87 I32T Neutral Disease Q695T7 E501K Disease Disease Q96N87 C12S Neutral Neutral Q695T7 R57C Disease Disease Q695T7 D173N Disease Neutral Q695T7 V252I Neutral Neutral Q695T7 R240Q Neutral Disease Q9NP91 A9G Neutral Neutral Q9C026 L653F Neutral Neutral Q8NAE3 F96V Neutral Neutral Q8WW38 A403G Neutral Neutral Q8WW38 E782D Neutral Neutral Q8WW38 S657G Disease Neutral Q8WW38 A1055V Neutral Neutral Q8WW38 E30G Disease Neutral O43286 G61S Neutral Disease O43286 Y371D Neutral Disease Q14146 V778G Neutral Neutral Q9BUA6 M46T Neutral Disease Q5SQ64 P34Q Neutral Neutral Q5SQ64 P39S Neutral Neutral Q5SQ64 A107T Neutral Neutral Q5SQ64 R167K Neutral Neutral Q86XR2 L543F Neutral Neutral Q86XR2 T229I Neutral Neutral Q86XR2 G603S Neutral Neutral P49137 A361S Neutral Disease P49137 A173G Neutral Neutral Q6ZNC4 A35S Neutral Neutral Q96HP0 P555L Neutral Disease Q96HP0 P250L Neutral Neutral Q96HP0 V1420L Neutral Neutral Q96HP0 R665G Neutral Neutral P51654 W296R Disease Disease P35680 S465R Disease Disease P35680 G492S Neutral Neutral Q96DF8 A31V Neutral Neutral Q96DF8 V336M Neutral Neutral Q96DF8 A423V Neutral Neutral P49755 S64Y Neutral Neutral Q6ZPD9 M350V Neutral Neutral P55895 M285R Disease Disease P55895 C41W Disease Disease P55895 C478Y Disease Disease P55895 R229Q Disease Disease P62906 T154P Neutral Disease Q9BT22 L325M Neutral Neutral Q9BT22 Q342P Disease Disease Q9BT22 S150R Disease Disease Q9BT22 S267N Neutral Neutral Q9BT22 D429E Neutral Neutral Q9BT22 S285L Disease Disease Q9BT22 Q455R Neutral Neutral P35453 Q317R Disease Disease P35453 S244A Neutral Neutral P35453 I314L Disease Disease P35453 R298W Disease Disease P35453 S308C Disease Disease A8MPS7 A263T Neutral Neutral O75419 V376M Neutral Neutral O75419 V81I Neutral Neutral P33981 D758N Neutral Neutral P33981 A97V Neutral Neutral Q96CA5 E223Q Neutral Neutral Q8IV50 S164F Neutral Neutral Q8IV50 I107V Neutral Neutral O43795 E969K Disease Neutral Q8WU90 V342E Neutral Disease Q8N335 L178F Neutral Neutral P21695 I54V Neutral Neutral P21695 A113P Neutral Disease P11511 R435C Disease Disease P11511 W39R Neutral Disease P11511 R375C Disease Disease P11511 R365Q Disease Disease P11511 R264C Neutral Disease P11511 T201M Neutral Neutral P11511 C437Y Disease Disease P20585 T1054A Neutral Neutral P20585 F709L Neutral Neutral P20585 R949Q Neutral Neutral P20585 T1045A Neutral Neutral P20585 V79I Neutral Neutral Q6NVU6 V47L Neutral Neutral Q96H72 P346L Neutral Neutral Q96H72 G28E Neutral Neutral Q9UP65 D411N Neutral Neutral Q9UP65 E21K Neutral Neutral Q9UP65 V142F Neutral Disease Q9UP65 P203S Neutral Neutral Q9UP65 T226S Neutral Neutral Q9UP65 R430C Neutral Neutral Q9UP65 A127V Neutral Neutral Q9UP65 R148G Neutral Neutral Q9UP65 T360P Neutral Disease Q9UP65 A38P Neutral Neutral Q9UP65 P151L Neutral Neutral Q9UP65 I143V Neutral Neutral Q9UGM3 R364G Neutral Disease Q9UGM3 G607V Disease Disease Q9UGM3 P856S Neutral Disease Q9UGM3 S52W Neutral Neutral Q9UGM3 R1176W Neutral Neutral Q9UGM3 Q337L Neutral Neutral Q9UGM3 T1961P Neutral Disease Q9UGM3 P65L Neutral Neutral Q9UGM3 P42T Neutral Disease Q9UGM3 T649M Neutral Neutral Q9UGM3 V60A Neutral Neutral Q9UGM3 P357S Neutral Disease Q9UGM3 M1169T Neutral Neutral Q9UGM3 R656W Neutral Disease Q9UGM3 Q420H Disease Neutral Q9UGM3 H1084Y Neutral Disease Q9UGM3 S54L Neutral Neutral Q9UGM3 T780M Neutral Neutral Q9UGM3 V1545M Neutral Disease Q9UGM6 G50S Neutral Disease Q9UGM6 A267P Neutral Disease Q9H4G1 H109P Neutral Neutral Q96MF6 P79H Neutral Neutral Q9NQZ5 R65P Neutral Neutral A6NDA9 K179N Neutral Neutral A6NDA9 T510P Neutral Neutral A6NDA9 C28Y Neutral Disease A6NDA9 V496A Neutral Neutral A6NDA9 L220F Neutral Neutral P21549 P11L Neutral Disease P21549 I244T Disease Neutral P21549 G170R Disease Disease P21549 F152I Disease Neutral P21549 R233C Disease Disease P21549 S205P Disease Disease P21549 S187F Disease Disease P21549 G156R Disease Disease P21549 G116R Disease Disease P21549 G82E Disease Disease P21549 G41V Disease Disease P21549 I340M Neutral Neutral P21549 G41R Disease Disease P21549 D183N Disease Disease P21549 R233H Disease Neutral Q5JU00 P35L Neutral Neutral Q5JU00 F261S Neutral Disease Q5JU00 H53R Neutral Neutral O75343 N316H Neutral Neutral O75343 M128I Neutral Neutral O75343 Y55C Neutral Disease P55040 R43G Neutral Neutral P04196 G436R Neutral Neutral P04196 H340R Neutral Neutral P04196 P204S Neutral Neutral P04196 I180T Neutral Neutral P04196 N493I Neutral Neutral P04196 D118G Neutral Neutral P04196 R448C Neutral Neutral Q9C0G0 N972T Neutral Neutral Q6ZP29 S16N Neutral Neutral P09919 A174T Neutral Neutral P09919 L157M Neutral Neutral Q9BX79 G339S Neutral Neutral Q9BX79 L517F Neutral Neutral Q9BX79 M527I Neutral Neutral Q9BX79 P90L Disease Neutral Q9BX79 T321P Disease Neutral Q9BX79 P293L Disease Disease Q9BX79 R655C Disease Disease Q9BX79 T644M Disease Disease Q96BA8 A411T Neutral Neutral P22309 I294T Disease Disease Q9HAW7 N129K Neutral Neutral P22309 A511P Neutral Disease P22309 Q357R Disease Disease P22309 A478D Disease Disease Q9HAW9 C277Y Neutral Disease P22309 H39D Disease Disease P22309 L175Q Disease Neutral Q9HAW9 M212L Neutral Neutral P54855 K523T Neutral Neutral P22309 G377V Disease Disease P22309 W461R Disease Disease P22309 H376R Disease Disease P22309 W354R Disease Disease P06133 D458E Neutral Neutral P22310 P24T Neutral Neutral Q9HAW8 T202I Neutral Disease P22309 A401P Disease Disease P22309 S375F Disease Disease P19224 A510P Neutral Disease P54855 D85Y Neutral Neutral P22309 P229Q Disease Neutral P22309 P387S Disease Disease P22309 K428E Disease Disease P22309 R336W Disease Disease P22309 F83L Disease Neutral P22309 Y486D Disease Disease P22309 A368T Disease Disease Q9HAW9 A173G Neutral Neutral P19224 R184S Neutral Neutral P22309 L15R Disease Disease P22309 C177R Disease Disease P22309 G71R Disease Disease P22309 G276R Disease Disease P22309 G308E Disease Disease P22309 V225G Disease Neutral Q9HAW9 G154A Neutral Neutral P22309 R367G Disease Disease P22309 R403C Disease Disease P06133 F109L Neutral Neutral P19224 S70Y Neutral Disease P19224 S7A Neutral Neutral Q9HAW7 W208R Neutral Neutral Q9HAW9 T202A Neutral Disease Q9HAW9 K132R Neutral Neutral P22309 S381R Disease Disease P22309 Q331R Disease Disease P22309 R209W Disease Disease P22309 A292V Disease Neutral Q9HAW8 M59I Neutral Neutral P22309 R336L Disease Disease P22309 G395V Disease Disease Q9Y4X1 G308R Neutral Disease Q6NUS8 C121G Neutral Disease P22309 E291V Disease Disease P22309 N400D Disease Disease P22309 R336Q Disease Disease P19224 T181A Neutral Neutral P06133 F396L Neutral Disease P22309 P34Q Disease Disease Q9HAW7 R131K Neutral Neutral P16662 H268Y Neutral Disease Q8N2Y8 P654L Neutral Neutral Q8N2Y8 A73T Neutral Neutral P01308 R89H Disease Disease P01308 R89L Disease Disease P01308 H34D Disease Disease Q496A3 G8R Neutral Neutral Q155Q3 K300R Neutral Neutral Q9BUI4 H243R Neutral Neutral O60733 R70Q Neutral Neutral O60733 R632W Disease Neutral O60733 K545T Disease Neutral O60733 D183N Neutral Neutral O60733 A343T Neutral Neutral O60733 V310E Disease Neutral O60733 S774T Neutral Neutral O60733 R63G Neutral Neutral O60733 V58I Neutral Neutral Q9Y6J3 K85N Neutral Neutral Q9UBQ7 R170Q Neutral Disease Q7Z3H4 E220D Neutral Neutral P13726 T36A Neutral Neutral P13726 R163W Neutral Disease P13726 I145V Neutral Neutral Q8WTQ1 I10V Neutral Neutral Q9UL12 E372D Neutral Neutral Q9UI17 G530A Neutral Disease Q9UI17 S279P Neutral Neutral Q8NCN5 Y109H Neutral Disease Q9UL12 R614H Neutral Disease Q9UL12 M648V Neutral Neutral Q9UI17 H109R Disease Disease Q9UL12 G22C Neutral Neutral Q9UI17 P646S Neutral Neutral P78324 V57A Neutral Neutral P78324 F133L Neutral Disease P78324 Q235R Neutral Neutral P78324 E189Q Neutral Disease P78324 E219G Neutral Neutral P78324 E77K Neutral Disease P78324 R275T Neutral Neutral P78324 A75G Neutral Neutral P78324 R125Q Neutral Neutral P78324 S109G Neutral Disease P78324 P459L Neutral Neutral P78324 N81H Neutral Neutral P78324 R250Q Neutral Disease P78324 S44L Neutral Disease P78324 V270I Neutral Neutral P78324 A20P Neutral Neutral P78324 P352L Neutral Neutral P78324 S107C Neutral Neutral P78324 I52T Neutral Neutral P78324 Q442R Neutral Neutral P78324 P338S Neutral Neutral P78324 H54R Neutral Neutral P78324 S96L Neutral Neutral P78324 V301L Neutral Neutral P78324 S366P Neutral Neutral P78324 Q260L Neutral Neutral P78324 E95D Neutral Neutral P78324 W68R Neutral Disease P78324 V262M Neutral Neutral P78324 R369Q Neutral Neutral P78324 K213N Neutral Neutral P78324 S107R Neutral Neutral P78324 D40E Neutral Neutral P78324 T180S Neutral Neutral P78324 I61N Neutral Disease P78324 A388E Neutral Neutral P78324 G356S Neutral Neutral P78324 P490L Neutral Neutral P78324 V221I Neutral Neutral P78324 S50T Neutral Neutral Q5KU26 I487V Neutral Neutral Q5KU26 P522S Neutral Neutral Q5KU26 K91E Neutral Neutral Q5KU26 G606S Neutral Disease P21580 A125V Neutral Disease P21580 A766P Neutral Neutral P21580 F127C Neutral Disease O43826 S55R Disease Disease O43826 G339C Disease Disease O43826 G149E Disease Disease O43826 G88D Disease Disease O43826 G50R Disease Disease O43826 R28H Disease Disease O43826 G339D Disease Disease O43826 N27K Disease Neutral O43826 L85P Disease Disease O43826 G150R Disease Disease O43826 A367T Disease Disease O43826 I278N Disease Disease O43826 N198I Disease Neutral O43826 S54R Disease Disease O43826 W118R Disease Disease O43826 G68R Disease Disease O43826 G376S Disease Disease O43826 C183R Disease Disease O43826 P191L Disease Disease O43826 L229P Disease Disease O43826 C176R Disease Neutral O43826 R300H Disease Disease O43826 R28C Disease Disease O43826 G20D Disease Disease O43826 H301P Disease Disease O43826 Y24H Disease Neutral O43826 Q133P Disease Disease O43826 A373D Disease Disease O43826 P153L Disease Disease Q9BQS7 A595T Neutral Neutral Q9H2C2 G101E Neutral Disease O15547 R232H Neutral Disease P36871 K68M Neutral Disease P36871 Y420H Neutral Disease P36871 R221C Neutral Disease P36871 V501I Neutral Neutral Q9BVW5 A267S Neutral Neutral Q9BVW5 P53R Neutral Neutral Q9BVW5 A111G Neutral Neutral P16152 P131S Neutral Neutral O75828 C4Y Neutral Neutral O75828 M235L Neutral Disease O75828 L84V Neutral Disease O75828 V93I Neutral Neutral O75828 V244M Neutral Disease O75828 P131S Neutral Neutral Q9C0B1 A405V Neutral Neutral Q9UK61 I1435V Neutral Neutral Q9UK61 R1046T Neutral Neutral Q9UK61 A831G Neutral Neutral Q6PGP7 R1296S Neutral Neutral Q6PGP7 L437V Neutral Neutral Q8WTW3 N392S Neutral Neutral Q5VWJ9 D83H Neutral Disease Q8TDR4 H145R Neutral Neutral P35222 S33F Disease Disease P35222 M688V Neutral Neutral P35222 S33L Disease Disease P14923 M696L Neutral Neutral P35222 S23R Disease Neutral P35222 D32G Disease Neutral P35222 T41I Disease Neutral P35222 S45P Disease Neutral P35222 S45F Disease Neutral P35222 T41A Disease Neutral P35222 S37Y Disease Disease P35222 G34E Disease Disease P35222 S37F Disease Disease P35222 G34R Disease Disease P35222 D32A Disease Neutral P35222 S33Y Disease Disease P35222 S37A Disease Neutral P35222 S37C Disease Disease P35222 D32Y Disease Disease P35222 I35S Disease Disease P23508 S751C Neutral Neutral P23508 S490L Disease Neutral P23508 P486L Disease Neutral P23508 R267L Disease Neutral P23508 R506Q Disease Neutral P23508 A698V Disease Neutral Q53SZ7 R222C Neutral Neutral Q53SZ7 R194G Neutral Neutral Q32MH5 V560I Neutral Neutral Q32MH5 Q135R Neutral Neutral Q67FW5 A341T Neutral Neutral Q96T53 G231E Neutral Neutral O75112 I345M Disease Neutral O75112 T206I Disease Neutral O75112 V635I Neutral Neutral O75112 S189L Disease Neutral O75112 D673N Disease Neutral O75112 V55I Neutral Neutral P00748 W505C Disease Disease P00748 R372P Disease Disease P00748 T328K Disease Neutral P00748 G589R Disease Disease P00748 G545D Neutral Neutral P00748 A340G Neutral Neutral P00748 D461N Disease Disease P00748 L414M Disease Neutral P00748 Y605H Neutral Neutral P00748 Y53C Disease Disease P00748 T328R Disease Neutral P00748 Q440K Disease Disease P00748 R417Q Disease Disease P00748 R142P Disease Disease P00748 A411T Disease Disease P00748 P342Q Neutral Neutral P00748 C590S Disease Disease P00748 P207A Neutral Neutral P31431 F12L Neutral Neutral Q5QGT7 Q82R Neutral Neutral P02746 G40D Disease Disease P02747 G34R Disease Disease Q9BXJ0 Q44R Neutral Neutral P02745 E23K Neutral Neutral Q9BXJ0 S163R Disease Disease Q9BR77 S25R Neutral Neutral Q9BR77 M335T Neutral Neutral Q9NPB8 T273I Neutral Disease Q86SQ4 K230Q Neutral Neutral Q8NCR6 P233Q Neutral Disease Q9NVI1 V86A Neutral Neutral Q9NVI1 Q686K Neutral Neutral Q9NVI1 S742C Neutral Neutral Q9NVI1 P55L Neutral Neutral Q15542 S130A Neutral Neutral Q9H1P6 R26H Neutral Neutral Q9H1P6 I99V Neutral Neutral Q15131 C358Y Neutral Neutral Q15131 P96L Neutral Disease Q15131 N168S Neutral Disease Q15131 R342H Neutral Neutral Q9UK23 I465T Neutral Neutral O43502 R249C Neutral Disease O43502 I144T Neutral Neutral O43502 T287A Neutral Neutral O43505 T253S Neutral Neutral Q13261 N182T Neutral Neutral O75631 A154P Neutral Neutral Q8IYG6 R12Q Neutral Neutral Q8IYG6 R507G Neutral Neutral Q8IYG6 D523H Neutral Neutral Q86Y26 T973N Neutral Neutral Q86Y26 R1113H Neutral Neutral Q86Y26 V785E Neutral Neutral Q86Y26 P985R Neutral Neutral Q86Y26 T781M Neutral Neutral Q86Y26 L22P Neutral Neutral Q16548 G82D Neutral Neutral Q16548 C19Y Neutral Neutral Q16548 N39K Neutral Neutral Q8NE18 A308S Neutral Neutral Q9NWQ9 L16V Neutral Neutral Q96PD6 S162P Neutral Disease Q3SYC2 M9V Neutral Neutral Q3SYC2 C313Y Neutral Neutral Q8WWF8 R75Q Neutral Neutral Q8WWF8 M191V Neutral Disease O15266 R153L Disease Disease O15266 R173C Disease Disease O15266 R168W Disease Disease O15266 L132V Disease Disease Q92539 S734L Disease Disease Q70J99 H858Q Neutral Disease Q70J99 K867E Neutral Neutral O75153 A633V Neutral Neutral P10909 D328N Neutral Neutral P10909 S396L Neutral Neutral P10909 N317H Neutral Neutral Q96KX1 S36Y Neutral Neutral O00391 A294S Neutral Neutral O00391 G200A Neutral Disease O00391 R256M Neutral Disease O00391 N591H Neutral Neutral O00391 H444R Neutral Neutral O00391 N114S Neutral Neutral Q9NUQ8 R510H Neutral Neutral Q9NUQ8 P503L Neutral Disease Q0VD83 A419P Neutral Neutral P53384 P39A Neutral Disease Q8TB37 N198T Neutral Neutral Q14746 N304K Neutral Neutral Q96LY2 T169M Neutral Neutral Q96LY2 R346H Neutral Neutral Q96AQ1 G302R Neutral Neutral Q7RTT9 V79E Neutral Disease Q7RTT9 N124K Neutral Disease Q7RTT9 P429T Neutral Disease P02750 P133S Neutral Neutral Q9BZD2 I239V Neutral Neutral Q9BZD2 V326I Neutral Neutral Q9BZD2 V452E Neutral Neutral Q14542 D5Y Neutral Neutral Q9BZD2 F158S Neutral Neutral Q14542 P94L Neutral Disease Q14542 N68K Neutral Neutral Q9BZD2 R18G Neutral Neutral Q9H228 L318Q Neutral Disease Q8IWZ3 G228C Neutral Neutral Q8IWZ3 L175M Neutral Neutral Q8IWZ3 N1760S Neutral Neutral O75179 H2560Y Neutral Neutral Q13224 S407N Neutral Neutral Q12879 K270E Neutral Neutral Q9HC52 G317V Neutral Neutral O14757 V312M Neutral Neutral O14757 R156Q Neutral Disease O14757 E223V Neutral Neutral O14757 V471I Neutral Neutral Q9NZJ0 T694K Neutral Neutral Q9NZJ0 A436V Neutral Neutral P98066 Q144R Neutral Disease Q99640 P417R Neutral Neutral Q99640 R246H Neutral Neutral Q99640 E103Q Neutral Neutral Q99640 R140C Neutral Disease Q99640 V445A Neutral Neutral Q99640 E351K Neutral Neutral O14921 L150F Neutral Neutral Q15695 S155G Neutral Neutral Q15695 S444N Neutral Neutral P01854 W359L Neutral Disease Q04446 Y329S Disease Disease Q04446 R524Q Disease Disease Q04446 R515C Disease Disease Q04446 L224P Disease Disease Q04446 T265S Neutral Neutral Q04446 H545R Disease Disease Q04446 V334I Neutral Disease Q04446 R190G Neutral Disease Q04446 T507A Neutral Neutral Q04446 R515H Disease Disease Q04446 F257L Disease Disease Q04446 H628R Disease Disease Q9Y6N5 I264T Neutral Neutral Q9BWV7 Q529H Neutral Neutral Q9BWV7 G425R Neutral Neutral Q9BWV7 T127A Neutral Neutral Q9BWV7 L202P Neutral Disease Q9BWV7 G445S Neutral Neutral Q9BWV7 G3R Neutral Neutral Q9BTT6 I193V Neutral Neutral P0C2Y1 E170D Neutral Disease Q9BXM0 V882A Neutral Neutral Q9BXM0 R1132G Neutral Neutral Q9BXM0 E495Q Neutral Neutral Q9BXM0 P1083R Neutral Neutral Q9BXM0 E1259K Neutral Neutral Q9BXM0 R1411C Neutral Neutral Q9BXM0 I921M Neutral Neutral Q9BXM0 K935E Neutral Disease Q9BXM0 A406T Neutral Neutral P18146 S145R Neutral Neutral P18146 N144K Neutral Neutral P18146 E219D Neutral Neutral Q9UDT6 R977P Neutral Neutral Q3MIX3 R17S Neutral Neutral P51801 F4L Neutral Neutral P51801 Y432H Disease Disease P51801 E578K Neutral Neutral P51800 Y315F Neutral Neutral P51801 S88R Neutral Disease P51800 R83G Neutral Neutral P51801 A349D Disease Disease P51800 R45H Neutral Disease P51801 A204T Disease Neutral P51801 R438C Disease Disease P51801 V334L Neutral Neutral P51801 V104I Neutral Neutral P51801 I419V Neutral Neutral P51800 A287V Neutral Neutral P51801 G214A Neutral Disease P51801 T562M Neutral Neutral P51801 P124L Disease Disease P51801 N143H Neutral Disease P51800 M67I Neutral Disease P51800 A447T Neutral Neutral Q6PJG9 V340A Neutral Neutral Q8NFT8 P433L Neutral Neutral Q8N766 S347N Neutral Neutral Q8N766 S345T Neutral Neutral Q8N766 L295S Neutral Neutral Q9H267 S514G Neutral Disease Q9H267 L30P Disease Disease Q14444 A263D Neutral Neutral Q14444 R616H Neutral Neutral Q14444 Q588H Neutral Neutral Q86X45 T232I Neutral Neutral Q86X45 I466T Neutral Neutral Q8IUH2 P96Q Neutral Neutral Q92947 R257Q Disease Disease Q92947 H403R Disease Neutral Q92947 R128G Disease Neutral Q92947 A298T Neutral Disease Q92947 A421V Disease Disease Q92947 C375R Disease Disease Q92947 P278S Disease Neutral Q92947 R138G Disease Neutral Q92947 N392D Disease Disease Q92947 R227P Disease Disease Q92947 L179R Disease Disease Q92947 G390A Disease Disease Q92947 L283P Disease Disease Q92947 Y295H Disease Disease Q92947 E365K Disease Neutral Q92947 L309W Disease Neutral Q92947 G178R Disease Disease Q92947 R88C Disease Neutral Q92947 V400M Disease Disease Q92947 S139L Disease Neutral Q92947 G354R Disease Disease Q92947 A195T Disease Disease Q92947 V148I Disease Neutral Q92947 G354S Disease Neutral Q92947 A293T Disease Neutral Q92947 G101R Disease Disease Q92947 R402W Disease Disease Q92947 R313W Disease Disease Q92947 R402Q Disease Disease Q92947 A382T Disease Disease Q92947 A122V Disease Disease Q92947 L407P Disease Disease Q92947 A349T Disease Neutral Q92947 N406K Disease Disease Q92947 R383C Disease Neutral Q92947 T416I Disease Disease Q92947 A298V Neutral Disease Q92947 R257W Disease Disease Q92947 R355H Disease Disease Q92947 R294W Disease Disease Q92947 F236L Disease Disease Q92947 A421T Disease Neutral Q92947 G390R Disease Disease Q92947 R355C Disease Neutral Q92947 C115Y Disease Disease Q92947 R161Q Disease Disease Q92947 Q333E Disease Disease Q92947 C308S Disease Neutral Q92947 R386Q Disease Disease Q92947 M266V Disease Disease Q92947 E414K Disease Disease Q92947 R94L Disease Neutral Q92947 M191T Disease Neutral Q92947 S305L Disease Disease Q92947 R383H Disease Disease Q92947 A433E Disease Disease Q92947 T429M Disease Disease Q8N6G2 K231N Neutral Neutral Q7Z7A3 A107V Neutral Neutral Q15653 R339W Neutral Neutral Q96GD4 T179M Neutral Neutral Q96GD4 A52V Neutral Neutral Q96GD4 H100Q Neutral Neutral Q96GD4 T298M Neutral Neutral P38936 S31R Neutral Neutral P38936 D149G Neutral Neutral Q8N0U6 Y106C Neutral Disease Q9P2H3 H105Q Disease Disease Q9P2H3 A701P Disease Disease Q9P2H3 T586S Neutral Neutral Q5QJU3 A134V Neutral Neutral Q8N7L0 R134C Neutral Neutral P82251 G63R Disease Disease Q9UM01 S238F Disease Disease Q9UM01 S489P Disease Disease P82251 I241T Disease Neutral P82251 A182T Disease Neutral P82251 W69L Disease Disease P82251 A331V Disease Disease Q9UM01 G54V Disease Disease Q9UM01 L124P Disease Disease P82251 A382T Disease Neutral P82251 G105R Disease Neutral P82251 S379R Disease Disease P82251 A224V Disease Disease P82251 I44T Disease Disease Q9UM01 T5I Disease Neutral P82251 L223M Neutral Neutral Q9UM01 A140P Disease Disease P82251 V330M Disease Neutral Q9UM01 S53L Disease Disease P82251 G195R Disease Disease P82251 R333W Disease Disease Q9UM01 K191E Disease Disease P82251 A70V Disease Neutral Q9UM01 S386R Disease Disease Q9UM01 L334R Disease Disease Q9UM01 G338D Disease Disease P82251 I187F Disease Disease Q9UM01 F152L Disease Neutral P82251 G259R Disease Disease P82251 T123M Disease Disease P82251 P52L Disease Disease Q9UM01 R333M Disease Disease Q9UM01 N365Y Disease Neutral Q9UM01 T188I Disease Disease P82251 P261L Disease Disease Q9UM01 M50K Disease Disease P82251 A354T Disease Disease Q9UM01 L261P Disease Disease P82251 W230R Disease Disease P82251 A126T Disease Disease P82251 V170M Disease Disease Q9UM01 E251D Disease Disease O95231 L42P Neutral Neutral O95231 M79V Neutral Neutral Q2TAC2 D777N Neutral Neutral Q2TAC2 A778T Neutral Neutral Q2TAC2 M834T Neutral Neutral Q2TAC2 Q811K Neutral Neutral Q2TAC2 Q321R Neutral Neutral Q2TAC2 E237Q Neutral Neutral Q2TAC2 R775G Neutral Neutral Q2TAC2 M480V Neutral Neutral Q86VP3 T185A Neutral Neutral P20396 L8V Neutral Neutral Q9Y5J6 G90S Neutral Neutral Q8WYP3 S197T Neutral Neutral Q16635 C118R Disease Disease Q16635 R94S Disease Disease Q16635 G197R Disease Disease Q09428 G7R Disease Disease Q09428 K719T Disease Disease Q09428 G1378R Disease Disease Q09428 I1424V Disease Neutral Q09428 M233R Disease Disease Q09428 G1381S Disease Disease Q09428 R1486K Disease Disease Q09428 L1551V Disease Neutral Q09428 R1493Q Disease Disease Q09428 D1471N Disease Disease Q09428 C435R Disease Disease Q09428 F686S Disease Disease Q09428 R841G Disease Disease Q09428 R1420C Disease Neutral Q09428 F591L Disease Neutral Q09428 S1369A Neutral Neutral Q09428 L582V Disease Disease Q09428 L1543P Disease Disease Q09428 V187D Disease Disease Q09428 G70E Disease Disease Q09428 R1393H Disease Neutral Q09428 R1182Q Disease Neutral Q09428 R1214Q Disease Disease Q09428 R74W Disease Disease Q09428 K1384Q Disease Neutral Q09428 D810N Neutral Disease Q09428 R1352P Disease Disease Q09428 E1506K Disease Disease Q09428 R1493W Disease Disease Q09428 V1572I Neutral Neutral Q09428 E501K Disease Disease Q09428 L1349Q Disease Neutral Q09428 G111R Disease Neutral Q09428 N406D Disease Neutral Q09428 H1023Y Disease Disease Q09428 K889T Disease Neutral Q09428 R1418H Disease Disease O60706 A1513T Disease Neutral Q09428 N1295K Disease Disease Q09428 L508P Disease Disease Q09428 R1352H Disease Neutral Q09428 K1336N Disease Neutral Q09428 C418R Disease Disease Q09428 V21D Disease Disease Q09428 V86A Disease Neutral Q09428 G1400R Disease Disease Q09428 T1130P Disease Neutral Q09428 L104V Neutral Neutral Q09428 F27S Disease Disease Q09428 P551R Disease Disease Q09428 R834C Neutral Disease Q09428 N188S Disease Neutral Q09428 A116P Disease Disease Q09428 H125Q Disease Neutral Q09428 D310N Disease Neutral Q09428 R620C Disease Neutral Q09428 D1471H Disease Disease Q09428 R1436Q Disease Disease Q09428 L1450P Disease Disease Q09428 R1379C Disease Disease Q09428 S1386F Disease Disease Q09428 R495Q Disease Disease Q09428 R1214W Disease Disease Q09428 F132L Disease Neutral Q09428 V1550D Disease Disease Q09428 V560M Neutral Disease Q09428 G1478R Disease Disease Q09428 V1360M Disease Neutral Q09428 L503P Disease Disease Q09428 D673N Neutral Neutral Q09428 T1138M Disease Neutral Q09428 S956F Disease Neutral Q09428 G716V Disease Disease Q09428 R275Q Neutral Neutral Q09428 L1147R Disease Neutral Q09428 V1360G Neutral Disease Q09428 R74Q Disease Neutral Q09428 G1342E Disease Disease Q09428 A1457T Disease Neutral Q09428 L213R Disease Disease P36551 R331W Disease Disease P36551 G189S Disease Disease P36551 L214R Disease Disease P36551 R328C Disease Disease P36551 G197W Disease Disease P36551 N272H Neutral Neutral P36551 K404E Disease Disease P36551 P249S Disease Disease P36551 S208F Disease Disease P36551 V135A Disease Neutral P36551 E201K Disease Disease P36551 R447C Disease Disease P36551 W427R Disease Disease P36551 H295D Disease Disease P36551 G280R Disease Disease P36551 V294I Neutral Neutral P36551 P249R Disease Disease P06734 R284Q Neutral Neutral P06734 R62W Neutral Neutral Q9H2Y9 L33F Neutral Neutral Q86XQ3 N204K Neutral Neutral Q8NEL0 R38Q Neutral Neutral Q3T8J9 M1418V Neutral Neutral P14770 N61S Disease Neutral P14770 F71S Disease Neutral P14770 L7P Disease Neutral P14770 L56P Disease Neutral P14770 C24R Disease Disease P14770 A156T Disease Neutral P14770 D37G Disease Neutral P14770 C113Y Disease Disease P49761 R486C Neutral Disease Q9BQ52 G806R Disease Neutral Q9BQ52 D436N Neutral Neutral Q9BQ52 A541T Neutral Neutral Q9BQ52 G487R Disease Disease Q9BQ52 R781H Disease Neutral Q9BQ52 S52F Neutral Neutral Q9BQ52 S627L Neutral Neutral Q9BQ52 S217L Neutral Neutral Q9BQ52 E622V Disease Disease Q9BQ52 R211Q Disease Neutral Q96B97 P382L Neutral Neutral Q9Y5K6 N581K Neutral Neutral Q9H0B6 P517S Neutral Neutral Q2KHT3 G906E Neutral Neutral Q5SZB4 K415R Neutral Neutral Q5SZB4 R381Q Neutral Neutral Q5SZB4 R248K Neutral Neutral Q5SZB4 R312Q Neutral Neutral Q6SJ96 R31P Neutral Neutral Q3KP66 C538R Neutral Neutral Q9UJQ1 D12G Neutral Neutral Q9UJQ1 Q103E Neutral Neutral Q9UJQ1 I81V Neutral Neutral Q9UJQ1 S158G Neutral Neutral Q14653 E377K Neutral Disease Q14653 R96Q Neutral Neutral Q14653 S427T Neutral Neutral P30566 D430N Disease Disease P30566 P318L Disease Disease P30566 D422Y Disease Disease P30566 V364M Disease Disease P30566 S31N Neutral Disease P30566 L423V Disease Disease P30566 S447P Disease Disease P30566 K246E Disease Disease P30566 R396H Disease Disease P30566 R374W Disease Disease P30566 R190Q Disease Neutral P30566 P100A Disease Neutral P30566 R141W Disease Disease P30566 Y114H Disease Disease P30566 K147M Neutral Neutral P30566 A2V Disease Neutral P30566 D268N Disease Disease P30566 S395R Disease Disease P30566 R452P Disease Disease P30566 T450S Disease Neutral P30566 I72V Disease Neutral P30566 L311V Disease Neutral P30566 S438P Disease Disease P30566 R396C Disease Disease P30566 M26L Disease Disease P30566 R303C Disease Disease P30566 A3V Disease Neutral P30566 R194C Disease Disease P30566 R426H Disease Disease Q711Q0 H666Q Neutral Neutral Q711Q0 N208K Neutral Neutral Q99445 R54C Neutral Disease Q13685 I250V Neutral Disease Q9HC24 T88I Neutral Neutral O75976 H505N Neutral Neutral O75976 K36E Neutral Neutral O75976 T899I Neutral Neutral O75976 E454G Neutral Neutral Q96KJ4 A139T Neutral Neutral Q96KJ4 S597G Neutral Neutral Q96KJ4 D463V Neutral Neutral Q580R0 P203L Neutral Neutral Q9BUJ0 R32Q Neutral Neutral Q9BUJ0 C61W Neutral Neutral Q9H3G5 A435V Neutral Disease Q6NTF7 R18L Neutral Neutral Q6NTF7 K121E Neutral Neutral Q6NTF7 E178D Neutral Neutral Q6NTF7 G105R Neutral Neutral Q6NTF7 K121N Neutral Disease Q9NRB3 P52H Neutral Neutral Q9NRB3 R109S Neutral Neutral Q9NRB3 A145P Neutral Disease Q9NRB3 P94L Neutral Neutral Q9NRB3 T61S Neutral Neutral P47901 R364H Neutral Neutral P47901 S267G Neutral Neutral P47901 K65N Neutral Neutral P47901 G191R Neutral Disease Q8WTP8 S88C Neutral Neutral Q8WTP8 D140N Neutral Neutral Q8WTP8 P15L Neutral Neutral Q9P2D7 E205D Neutral Neutral Q9P2D7 V441L Neutral Neutral Q9P2D7 R1663C Neutral Disease Q9P2D7 V1502M Neutral Neutral Q13950 T205R Disease Disease Q13950 R193C Disease Disease Q13950 R169Q Disease Disease Q13950 L113R Disease Disease Q13950 F121C Disease Disease Q13950 R190W Disease Disease Q13950 C123R Disease Disease Q13950 R225W Disease Disease Q13950 R225Q Disease Disease Q13950 T200A Disease Disease Q13950 L199F Disease Disease Q13950 F197S Disease Disease Q13950 S118R Disease Disease Q13950 M175R Disease Disease Q13950 Q209R Disease Disease Q13950 G511S Disease Neutral Q13950 R190Q Disease Disease Q13950 S191N Disease Disease Q8N612 M491T Neutral Neutral Q8N612 Q754H Neutral Neutral Q8N612 R619L Neutral Neutral Q9HB65 Q11E Neutral Neutral A8K0R7 P531S Neutral Neutral A8K0R7 V693M Neutral Neutral A8K0R7 F731L Neutral Neutral Q4G0A6 R324K Neutral Neutral Q4G0A6 A355V Neutral Neutral Q4G0A6 S262L Neutral Neutral Q4G0A6 M322T Neutral Neutral Q4G0A6 D183A Neutral Neutral Q4G0A6 M655V Neutral Neutral P05305 K198N Neutral Neutral Q96Q27 P160S Neutral Neutral P07225 G482C Disease Disease P07225 N258S Disease Disease P07225 R561G Disease Disease P07225 Y485C Disease Disease P07225 K196E Disease Neutral O60909 Q122H Neutral Neutral Q9UBP5 T96A Neutral Disease Q9UBP5 V140M Neutral Neutral Q9NQ87 H47R Neutral Neutral Q9UBP5 L100S Neutral Disease Q9UBP5 D98A Neutral Disease Q9Y210 R895C Disease Disease Q9Y210 P112Q Disease Disease Q9Y210 S270T Disease Disease Q9Y210 N143S Disease Disease Q9Y210 E897K Disease Disease Q9Y210 N157T Neutral Neutral Q99741 D295N Neutral Neutral Q99741 R378H Neutral Disease Q99741 T299M Neutral Neutral Q99741 V441I Neutral Neutral Q99741 T238A Neutral Neutral O15552 L211H Neutral Disease Q9BUN8 I171V Neutral Neutral P01023 C972Y Neutral Disease P01023 V1000I Neutral Neutral P01023 R704H Neutral Disease P01023 D639N Neutral Neutral P01023 L815Q Neutral Disease P14868 L426F Neutral Disease A8K855 S186G Neutral Neutral A8K855 M262T Neutral Neutral A8K855 F27I Neutral Neutral A8K855 R375K Neutral Neutral A8K855 T248I Neutral Neutral P20908 G530S Disease Disease P13942 E1628D Neutral Neutral P20908 G1489D Disease Disease P25940 V1691I Neutral Neutral P13942 G808E Disease Disease P13942 E824K Neutral Neutral P13942 D593G Neutral Neutral P13942 P1316T Neutral Neutral P25940 R134H Neutral Neutral P13942 P621T Disease Neutral P25940 V1428M Neutral Neutral P13942 P879L Neutral Neutral P25940 I1594M Neutral Neutral P25940 R1207P Neutral Neutral P13942 G1441E Disease Disease P12107 G1516V Disease Disease P13942 G661R Disease Disease P13942 R1600Q Neutral Disease P12107 G625V Disease Disease P20908 C1639S Disease Disease P13942 R1034C Disease Disease P12107 G676R Disease Disease O15232 E252K Neutral Disease O15232 T120M Disease Neutral O15232 F105S Disease Disease O15232 A128P Disease Disease O15232 P11S Neutral Neutral O15232 A219D Disease Disease O15232 I192N Disease Disease O15232 V194D Disease Disease O15232 T303M Disease Neutral O15232 R121W Disease Disease O15232 E134K Disease Disease O15232 C304S Disease Disease P00740 W431G Disease Disease P00740 K387E Disease Neutral P00740 C102R Disease Disease P04070 R32C Disease Neutral P04070 G343D Disease Disease P04070 R272C Disease Neutral P00740 C396F Disease Disease P00740 G58R Disease Disease P00740 A397P Disease Disease P04070 S161R Disease Disease P00740 I112S Disease Disease P00740 L321Q Disease Disease P00740 C407R Disease Disease P04070 R328C Disease Neutral P00740 N113K Disease Disease P00740 C97S Disease Disease P04070 R57W Disease Disease P00740 D410H Disease Disease P04070 N298D Disease Neutral P04070 G334S Disease Disease P04070 V76M Disease Neutral P04070 R271W Disease Disease P00740 V228F Disease Disease P00740 R449Q Disease Neutral P00740 V227F Disease Disease P00740 E67K Disease Disease P00740 P333H Disease Neutral P00740 Y91C Disease Disease P00740 M394K Disease Disease P04070 R394W Disease Disease P00740 I344L Disease Disease P00740 S411G Disease Disease P00740 G432V Disease Disease P00740 R43W Disease Disease P00740 A279T Disease Neutral P00740 C178W Disease Disease P00740 L318R Disease Disease P00740 V419E Disease Neutral P00740 C119F Disease Disease P00740 T194A Neutral Neutral P04070 F118L Disease Disease P04070 G392R Disease Disease P04070 G418D Disease Disease P04070 R51C Disease Neutral P00740 G357R Disease Disease P00740 S49P Disease Disease P00740 N48I Disease Disease P00740 W453R Disease Disease P04070 A388T Disease Disease P00740 G125E Disease Disease P00740 C170F Disease Disease P00740 E79D Disease Disease P00740 R43Q Disease Disease P00740 W356C Disease Disease P00740 I136T Disease Neutral P00740 R191H Disease Neutral P00740 T426P Disease Disease P00740 I316F Disease Disease P00740 C252Y Disease Disease P00740 R226Q Disease Disease P00740 C155F Disease Disease P00740 V30I Disease Neutral P00740 R226W Disease Disease P00740 G357E Disease Disease P00740 Q167H Disease Neutral P00740 C178R Disease Disease P04070 A301V Disease Disease P00740 R191C Disease Neutral P00740 P101R Disease Disease P00740 C134Y Disease Disease P00740 G58A Disease Disease P04070 G114R Disease Neutral P00740 R379Q Disease Neutral P04070 G145R Disease Disease P00740 I7F Neutral Neutral P00740 C119R Disease Disease P04070 T340M Disease Disease P04070 R194C Disease Disease P00740 V227D Disease Disease P00740 A366D Disease Disease P00740 I17N Disease Disease P00740 E291V Disease Neutral P04070 R328H Disease Neutral P00740 R46S Disease Disease P04070 R42H Disease Disease P00740 G351D Disease Disease P00740 Q241K Disease Disease P00740 C268W Disease Neutral P00740 G253R Disease Disease P04070 R220W Disease Disease P00740 F395I Disease Neutral P00740 G442R Disease Disease P00740 E124K Disease Disease P00740 C108S Disease Disease P04070 T436N Disease Neutral P00740 L52S Disease Disease P00740 R449W Disease Neutral P00740 N306S Disease Neutral P04070 R42C Disease Disease P04070 R271Q Disease Neutral P00740 E54G Disease Disease P04070 I445M Disease Disease P00740 G125V Disease Disease P00740 R46T Disease Disease P00740 L383F Disease Neutral P04070 A43T Neutral Disease P04070 Q226H Disease Disease P04070 C183R Disease Disease P04070 P321L Disease Disease P00740 Y115C Disease Disease P00740 R75Q Disease Disease P00740 R43L Disease Disease P00740 G106D Disease Disease P00740 P414T Disease Disease P00740 Q241H Disease Disease P04070 R220Q Disease Neutral P00740 I390F Disease Neutral P04070 R211W Disease Disease P00740 C382Y Disease Disease P04070 P289L Disease Neutral P00742 L7I Neutral Neutral P00740 G125R Disease Disease P00740 G413R Disease Disease P04070 P369L Disease Neutral P00742 A152T Neutral Disease P04070 C147Y Disease Disease P00740 D110N Disease Disease P00742 Q30H Neutral Neutral P04070 G433S Disease Disease P00740 I454T Disease Disease P00740 E66V Disease Disease P00740 L383I Disease Neutral P04070 H108N Disease Neutral P00740 G432S Disease Disease P04070 D401N Disease Disease P00740 R294G Disease Neutral P04070 P210L Disease Neutral P04070 R38W Disease Disease P00740 G442E Disease Disease P22891 R295H Neutral Neutral P04070 A178P Disease Disease P22891 E70K Neutral Disease P00740 C435Y Disease Disease P00740 C396S Disease Disease P00740 S411I Disease Disease P00740 E73K Disease Disease P04070 R220P Disease Disease P04070 R189W Disease Neutral P04070 L265F Disease Neutral P00740 R226G Disease Disease P04070 G89C Disease Disease P04070 C426Y Disease Disease P04070 H253Q Disease Disease P00740 E433A Disease Neutral P04070 G423S Disease Disease P04070 E62A Disease Disease P00740 G106S Disease Disease P04070 R57G Disease Disease P00740 F55C Disease Disease P00740 S169C Disease Disease P04070 R57Q Disease Disease P04070 S312L Disease Neutral P00740 G160E Disease Disease P04070 V367A Disease Neutral P00740 E73V Disease Disease P00740 N283D Disease Neutral P00740 W431R Disease Disease P04070 R211Q Disease Disease P04070 G109R Disease Disease P00740 T342M Disease Disease P00740 G253E Disease Disease P00740 K45N Disease Disease P04070 Y441H Disease Disease P00740 R379G Disease Neutral P00742 G192R Neutral Neutral P00740 R404T Disease Neutral P00740 R294Q Disease Neutral P00740 S430T Disease Disease P00740 C252S Disease Disease P00740 F71S Disease Disease P00740 F395L Disease Neutral P00740 G363W Disease Disease P00740 P333T Disease Neutral P00740 C407S Disease Disease P04070 A388V Disease Disease P00740 T461P Neutral Disease P00740 T84R Disease Disease P00740 E433K Disease Disease P00740 A265T Disease Disease P00740 F424V Disease Neutral P00740 G139D Disease Disease P04070 A301T Disease Disease P00740 C28R Disease Disease P04070 M385I Disease Disease P04070 H149P Disease Disease P00740 H302R Disease Disease P04070 W444C Disease Disease P00740 V228L Disease Disease P00740 K362E Disease Neutral P04070 E49D Disease Disease P04070 A309T Disease Neutral P04070 H244Y Disease Neutral P04070 I243T Disease Disease P00740 Y450C Disease Disease P00740 Q96P Disease Disease P04070 S294N Disease Neutral P00740 C28Y Disease Neutral P04070 S312P Disease Neutral P00740 I443T Disease Disease P00740 G412E Disease Disease P00740 D93G Disease Disease P00740 A436V Disease Disease P04070 G324R Disease Disease P00740 G139S Disease Disease P00740 E53A Disease Disease P04070 W14G Disease Disease P00740 T342K Disease Disease Q68BL8 Y10C Neutral Neutral Q68BL8 W470R Neutral Neutral O95050 F254C Neutral Disease O95050 M205V Neutral Neutral O95050 E219G Neutral Neutral O95050 N246S Neutral Neutral O95050 R258H Neutral Neutral O95050 D28N Neutral Neutral Q6PEZ8 R44W Neutral Disease P55212 A109T Neutral Neutral P55212 T182S Neutral Neutral P55212 E35K Neutral Disease Q96ER9 F360S Neutral Neutral Q9HBH7 A40V Neutral Neutral Q9HBH7 A17V Neutral Neutral Q9HBH7 M14V Neutral Neutral Q9HBH7 S11N Neutral Neutral Q9HBH7 M66I Neutral Neutral Q9HBH7 V9L Neutral Neutral Q9HBH7 S13I Neutral Neutral Q8NEF3 H32L Neutral Neutral Q8NEF3 E354G Neutral Neutral Q8NEF3 S144N Neutral Neutral Q8NEF3 K341N Neutral Neutral O14669 G116C Neutral Neutral Q9H0R6 N263S Neutral Neutral Q9H0R6 A11V Neutral Neutral Q9UK53 N359S Disease Disease Q9UK53 C358S Disease Disease Q9UK53 A335D Disease Neutral A0PJX8 R284H Neutral Neutral Q9UBT2 L307R Neutral Disease P24855 R244Q Neutral Neutral P24855 A246P Neutral Disease P24855 R107G Neutral Disease P24855 R2S Neutral Neutral P24855 V114M Neutral Neutral P24855 Q31E Neutral Neutral P24855 P154A Neutral Disease P24855 C231Y Neutral Disease P24855 G127R Neutral Disease P24855 R207C Neutral Disease P24855 G262D Neutral Disease Q14896 R809H Disease Neutral Q14896 D228N Disease Neutral Q14896 R667P Disease Disease Q14896 R501Q Disease Neutral Q14896 H257P Disease Disease Q14896 R667H Disease Disease Q14896 N947T Disease Disease Q14896 R281Q Neutral Neutral Q14896 V189I Neutral Neutral Q14896 E450Q Disease Disease Q14896 R326Q Disease Neutral Q14896 Q997R Disease Neutral Q14896 R833W Disease Neutral Q14896 G506R Disease Disease Q14896 R833T Disease Neutral Q00872 H481Q Neutral Neutral Q14896 R732C Disease Disease Q14896 G489R Disease Disease Q14896 E541Q Disease Disease Q14896 L544M Neutral Neutral Q14896 R382W Neutral Neutral Q14324 V625I Neutral Neutral Q14896 V256I Disease Neutral Q14896 Y237S Disease Disease Q14896 C565R Disease Disease Q14896 G279A Disease Neutral Q14896 L352P Disease Disease Q14896 R819Q Disease Neutral Q14896 Q997E Disease Neutral Q14896 L383V Neutral Disease Q14896 R1001W Neutral Disease Q14896 T59A Disease Neutral Q14896 R1001Q Disease Disease Q14896 V219L Disease Neutral Q14896 P872H Disease Neutral Q14896 G5R Disease Neutral Q14896 P161S Disease Neutral Q14896 D603V Disease Neutral Q14324 R1090H Neutral Neutral Q14896 I1130T Disease Neutral Q14896 R457H Disease Disease Q14896 E258K Disease Disease Q14896 K810R Disease Disease Q14896 P607L Disease Neutral Q14896 V1114I Disease Neutral Q14896 A521T Neutral Disease Q14896 A1193T Disease Disease Q14896 V158M Neutral Neutral Q14896 A1254T Disease Disease Q14896 F1112I Disease Neutral Q14896 D604N Disease Neutral Q14896 R282W Disease Neutral Q14896 G278E Disease Neutral Q14896 A832T Disease Neutral Q14896 R1047C Neutral Disease Q14896 S236G Disease Neutral Q14896 A832V Disease Neutral Q14896 D769N Disease Disease Q14896 P1002Q Disease Disease Q14896 G522W Disease Disease Q14896 V895M Disease Neutral Q14896 R653H Disease Neutral Q14896 R501W Disease Disease Q14896 R494Q Disease Neutral Q14324 G52S Neutral Neutral Q14896 W791R Disease Disease Q14896 G415S Neutral Disease Q14896 N754K Disease Disease Q86WB0 T271A Neutral Neutral Q86WB0 R363H Neutral Neutral Q86WB7 V409I Neutral Neutral Q86WB7 Y387H Neutral Neutral Q86WB7 M403T Neutral Neutral Q86WB7 V445A Neutral Neutral Q86WB7 V292I Neutral Neutral Q8IZM9 M70L Neutral Disease Q96QD8 N48K Neutral Neutral Q8WUX1 M451T Neutral Disease O00444 E830D Neutral Neutral O00444 W519S Neutral Neutral O00444 P317L Neutral Neutral O00444 S232T Neutral Neutral O00444 A226T Neutral Neutral O00444 R146H Neutral Neutral O00444 N449D Neutral Neutral O00444 Y86C Neutral Disease Q5VZK9 A639G Neutral Neutral Q5VZK9 N1117S Neutral Neutral Q5VZK9 V77I Neutral Neutral Q5VZK9 P545L Neutral Neutral Q8ND23 L1022M Neutral Neutral Q8IZN3 T334M Neutral Neutral Q676U5 T300A Neutral Neutral Q8N0S2 E132D Neutral Neutral Q8N0S2 P317A Neutral Neutral Q8N0S2 K183R Neutral Neutral Q8NA92 R70H Neutral Disease Q8NA92 K112R Neutral Neutral Q8NA92 P157S Neutral Neutral Q0VAF6 L111M Neutral Neutral P34981 N10K Neutral Neutral P25189 K236E Disease Neutral P25189 T124M Disease Disease P25189 I62M Disease Neutral P25189 G123C Disease Disease P25189 D118N Disease Neutral P25189 T65A Disease Neutral P25189 K130R Disease Neutral P25189 G110D Disease Disease P25189 S44F Disease Disease P25189 S63F Disease Disease P25189 R244L Neutral Neutral P25189 V136E Disease Disease P25189 T139N Disease Neutral P25189 C127Y Disease Disease P25189 D134E Disease Disease P25189 R98S Disease Disease P25189 R98C Disease Disease P25189 I30M Disease Neutral P25189 K138N Disease Neutral P25189 S78W Disease Disease P25189 G137S Disease Neutral P25189 D109N Disease Disease P25189 I114T Disease Disease P25189 D128N Disease Disease P25189 S78L Disease Neutral P25189 I135L Disease Neutral P25189 S51F Disease Disease P25189 V58F Disease Disease P25189 L170R Disease Disease P25189 D75V Disease Disease P25189 A221T Disease Neutral P25189 R98H Disease Disease P25189 S54C Disease Disease P25189 I99T Disease Neutral P25189 V92M Disease Neutral P25189 P132L Disease Disease P25189 Y68C Disease Disease P25189 V146F Disease Disease P25189 I112T Disease Disease P25189 D35Y Disease Disease P25189 I89N Disease Disease P25189 N131K Disease Disease P25189 R98P Disease Disease P25189 S63C Disease Neutral P25189 H81R Disease Disease P25189 D128E Disease Neutral P25189 N122S Disease Disease P25189 T34I Disease Disease P25189 Y82C Disease Disease P25189 D60H Disease Neutral P25189 D134N Disease Disease P25189 G167A Disease Neutral P25189 I162M Disease Neutral P25189 N116H Disease Disease P25189 D134G Disease Disease P25189 I62F Disease Neutral P25189 G163R Disease Disease P25189 G103E Disease Disease P25189 D90E Disease Neutral P25189 S140T Disease Neutral P25189 T124K Disease Disease P25189 I135T Disease Disease P25189 T65I Disease Disease P25189 K96E Disease Neutral P25189 G167R Disease Disease P25189 W101C Disease Disease P25189 S54P Disease Disease P25189 T143M Disease Neutral P25189 G93E Disease Disease P25189 E97V Disease Disease P25189 V32F Disease Disease P25189 Y145S Disease Neutral P22749 T119I Neutral Neutral Q9H845 R477Q Neutral Neutral Q5T481 P173T Neutral Neutral Q5T481 W768S Neutral Neutral Q96DR7 F203S Neutral Neutral Q96DR7 L29V Neutral Neutral Q5T6X5 P91S Neutral Disease P35251 R613L Neutral Neutral P35251 Q955K Neutral Neutral P35251 S1146L Neutral Neutral P35251 E692D Neutral Neutral P35251 I598V Neutral Neutral Q9NVQ4 L127S Neutral Neutral Q9NVQ4 A117T Neutral Neutral P08034 V13L Disease Disease P08034 Y151S Disease Disease P08034 V177A Disease Disease P08034 E208G Disease Disease P08034 C168Y Disease Disease P08034 T86S Disease Disease P08034 H94Q Disease Disease P08034 F69L Disease Disease P08034 H126Y Disease Disease P08034 S49P Disease Disease P08034 A40T Disease Disease P08034 P158R Disease Disease P08034 C179R Disease Disease P08034 R142W Disease Disease P08034 S26L Disease Disease P08034 V136A Disease Disease P08034 Y135C Disease Disease P08034 S49Y Disease Disease P08034 I127S Disease Disease P08034 T55A Disease Disease P08034 W24C Disease Disease P08034 C53S Disease Disease P08034 P172L Disease Disease P08034 L81F Disease Neutral P08034 F141L Disease Disease P08034 F149V Disease Disease P08034 P158A Disease Neutral P08034 L25P Disease Disease P08034 P172S Disease Disease P08034 L204V Disease Disease P08034 V37M Disease Disease P08034 G159D Disease Disease P08034 S50P Disease Disease P08034 V38M Disease Disease P08034 R164W Disease Disease P08034 W3R Disease Disease P08034 Y157C Disease Disease P08034 W133R Disease Disease P08034 S11G Disease Neutral P08034 L156R Disease Disease P08034 C173R Disease Disease P08034 L239I Disease Neutral P08034 S85C Disease Neutral P08034 R219H Disease Neutral P08034 I28N Disease Disease P08034 G21D Disease Disease P08034 C201R Disease Disease P08034 F193C Disease Disease P08034 R75Q Disease Disease P08034 V35M Disease Disease P08034 W3S Disease Disease P08034 K124N Disease Disease P08034 G59R Disease Disease P08034 R22G Disease Disease P08034 I20S Disease Disease P08034 P172R Disease Disease P08034 E208K Disease Disease P08034 W77S Disease Disease P08034 C168R Disease Disease P08034 T8I Disease Neutral P08034 H16P Disease Disease P08034 C201Y Disease Disease P08034 T55I Disease Disease P08034 L108P Disease Disease P08034 L90H Disease Neutral P08034 R164Q Disease Neutral P08034 V125D Disease Disease P08034 I30T Disease Disease P08034 L89P Disease Disease P08034 R183S Disease Disease P08034 L56F Disease Neutral P08034 N205S Disease Disease P08034 L83P Disease Disease P08034 M34T Disease Disease P08034 V91M Disease Disease P08034 R22Q Disease Disease P08034 R264C Disease Neutral P08034 F193L Disease Disease P08034 F29L Disease Neutral P08034 L9W Disease Disease P08034 T55R Disease Disease P08034 P172A Disease Disease P08034 T8P Disease Neutral P08034 V181A Disease Disease P08034 K104T Disease Disease P08034 V13M Disease Disease P08034 P158S Disease Neutral P08034 I28T Disease Neutral P08034 T191A Disease Neutral P08034 V139M Disease Disease P08034 P184L Disease Disease P08034 S138N Disease Disease P08034 R22P Disease Disease P08034 S198F Disease Disease P08034 L25F Disease Disease P08034 R215W Disease Disease P08034 R215Q Disease Neutral P08034 F180L Disease Disease P08034 H100Y Disease Neutral P08034 M194V Disease Disease P08034 R238H Disease Neutral P08034 L90V Disease Neutral P08034 T130I Disease Disease P08034 R75P Disease Disease P08034 F180S Disease Disease P08034 G12S Disease Disease P08034 I213V Disease Neutral P08034 P70A Disease Disease P08034 V181M Disease Disease P08034 I203N Disease Disease P08034 V63I Disease Neutral P08034 P87A Disease Disease P08034 S128P Disease Disease P08034 R183H Disease Disease P08034 T86N Disease Disease P08034 Q80R Disease Disease P08034 N205I Disease Disease P08034 T86A Disease Disease P08034 V192F Disease Disease P08034 E186K Disease Disease P08034 K103E Disease Disease P08034 M34K Disease Disease P08034 V120E Disease Neutral P08034 R142E Disease Disease P08034 R107W Disease Disease P08034 R183C Disease Disease P08034 S182T Disease Neutral P08034 V189I Disease Neutral P08034 R230C Disease Disease P08034 R220G Disease Neutral P08034 K187E Disease Disease P08034 F235C Disease Neutral P08034 Y65H Disease Disease P08034 E41K Disease Disease P08034 R15Q Disease Neutral P08034 Y7C Disease Neutral P08034 C64F Disease Disease P08034 P184R Disease Disease P08034 V23A Disease Disease P08034 F153S Disease Disease P08034 P87L Disease Disease P08034 F149I Disease Disease P08034 C60F Disease Disease P08034 Y211H Disease Neutral P08034 R75W Disease Disease P08034 A39V Disease Disease P08034 W44L Disease Disease P08034 G199R Disease Disease P08034 V189G Disease Disease P08034 L156F Disease Disease P08034 M93V Disease Disease P08034 V95M Disease Disease P08034 L204F Disease Disease P08034 H94D Disease Disease P08034 E102G Disease Disease P08034 S26W Disease Disease P08034 C280G Disease Neutral P08034 P87S Disease Disease P08034 A40V Disease Disease P08034 I30N Disease Disease P08034 G159S Disease Disease P08034 L131P Disease Disease P08034 A147D Disease Disease P08034 Y160H Disease Disease P08034 N14K Disease Disease P08034 W133C Disease Disease P08034 S85F Disease Disease P08034 C64S Disease Disease P08034 M34V Disease Disease P08034 Y65C Disease Disease P08034 A161P Disease Neutral P08034 V177E Disease Disease P08034 G59C Disease Disease P08034 I127M Disease Disease P08034 M34I Disease Disease P08034 Q57H Disease Disease P08034 R230L Disease Neutral P08034 R142Q Disease Disease P08034 A39P Disease Disease P08034 D178Y Disease Disease P08034 H94Y Disease Disease P08034 E146K Disease Disease P08034 R15W Disease Neutral P08034 V84I Disease Neutral P08034 V43M Disease Disease P08034 R219C Disease Disease Q8WV19 I109V Neutral Neutral P26651 V324F Neutral Neutral P26651 I259F Neutral Neutral P26651 P37S Neutral Neutral Q9H3P7 E187D Neutral Neutral O14686 R4949H Neutral Disease Q9Y603 P212L Neutral Disease P51854 I152T Neutral Disease P51854 L24F Neutral Disease Q8N159 A518T Disease Neutral Q8N159 A279P Disease Disease Q8N159 L430P Disease Disease Q8N159 S410P Disease Disease Q8N159 W484R Disease Disease Q8N159 C200R Disease Disease Q9HD34 S11A Neutral Neutral Q96L73 M2250I Neutral Neutral Q96L73 S726P Neutral Neutral Q96L73 A691T Neutral Neutral Q96L73 L1091I Neutral Neutral Q96L73 L1637P Disease Disease Q96L73 R2005Q Disease Neutral Q96L73 M2261T Neutral Neutral Q96L73 Y1997C Disease Disease Q96L73 G1955D Disease Disease Q96L73 C2183S Disease Disease Q96L73 H2143Q Disease Disease Q96L73 C1925R Disease Disease Q96L73 G1792V Disease Disease Q96L73 C1674W Disease Disease Q96L73 I1687N Disease Disease Q96L73 R2017Q Disease Disease Q96L73 V614L Neutral Neutral Q96L73 R1984Q Disease Disease Q96L73 H1616L Disease Disease Q96L73 A1036P Neutral Neutral Q96L73 R2017W Disease Disease Q9Y2V3 D44E Neutral Neutral Q9Y2V3 R192Q Disease Disease Q9NPI5 E178K Neutral Neutral Q9GZR2 R141K Neutral Neutral Q9GZR2 T283A Neutral Neutral Q13569 G199S Neutral Neutral Q13569 V367M Neutral Neutral Q9Y620 D418Y Disease Neutral Q9Y620 D97H Neutral Neutral Q9Y620 N593S Disease Disease Q9Y620 L30V Neutral Neutral Q12962 I92T Neutral Neutral Q6ZW61 Q386R Neutral Neutral Q6ZW61 N238K Neutral Neutral Q6ZW61 P159L Disease Neutral Q6ZW61 G540V Disease Disease Q6ZW61 N461H Neutral Neutral Q6ZW61 I39T Neutral Neutral Q6ZW61 I170V Neutral Neutral Q6ZW61 R484K Neutral Neutral Q6ZW61 S429T Neutral Neutral Q6ZW61 K195R Neutral Neutral Q6ZW61 A615V Neutral Neutral Q6ZW61 E126D Neutral Neutral Q6ZW61 A289P Disease Disease Q6ZW61 D467N Neutral Neutral Q8NES3 F188L Disease Disease Q9NX31 V74G Neutral Neutral Q13018 M292V Neutral Neutral Q13018 P177S Neutral Disease Q13018 G1106S Neutral Neutral Q9UBG0 H1156R Neutral Neutral Q13018 H300D Neutral Neutral Q13018 R142Q Neutral Neutral Q13018 I279V Neutral Neutral P22897 T167I Neutral Neutral Q9UBG0 V43I Neutral Neutral Q13018 R404H Neutral Neutral P17735 G362V Disease Disease Q9H9A5 P736S Neutral Neutral P10415 A43T Neutral Neutral P10415 P59S Disease Neutral P10415 V93I Disease Neutral P10415 T7S Neutral Neutral Q12948 F112S Disease Disease Q12948 S131L Disease Disease Q12948 I87M Disease Disease Q12948 M161K Neutral Disease Q99958 S125L Disease Disease Q12948 I126M Disease Neutral Q12948 S82T Disease Disease O95925 H92R Neutral Neutral Q8NFW1 G320S Neutral Disease Q8NFW1 A938D Neutral Neutral Q8NFW1 P703T Neutral Neutral Q9NX58 H265R Neutral Neutral Q9NX58 D151Y Neutral Neutral A5D8W1 S22R Neutral Neutral A5D8W1 T885M Neutral Disease A5D8W1 V490M Neutral Neutral A5D8W1 R306C Neutral Disease A5D8W1 P459L Neutral Neutral O15151 I175T Neutral Neutral O15151 T406I Neutral Neutral Q14204 H4029Q Neutral Neutral Q14204 D3902N Neutral Disease O43164 R297Q Neutral Neutral O43164 A705T Neutral Neutral P36269 I475V Neutral Neutral P19440 S51L Neutral Disease P19440 N419D Neutral Disease P19440 V272A Neutral Neutral P36269 Q332H Neutral Neutral P19440 K52E Neutral Disease P36269 L11I Neutral Neutral P36269 K330R Neutral Neutral P19440 A177V Neutral Disease Q13421 R309P Neutral Disease Q13421 M601V Neutral Neutral Q13421 A72V Neutral Neutral Q53HC0 S70C Neutral Neutral Q53HC0 R281H Neutral Neutral Q92730 P44R Neutral Disease Q969S8 G584C Neutral Neutral Q86VQ3 D357G Neutral Neutral Q86VQ3 K341E Neutral Neutral Q86VQ3 A461T Neutral Neutral Q86VQ3 R487T Neutral Neutral Q5VTJ3 T133P Neutral Neutral Q5VTJ3 H259N Neutral Neutral Q9NR55 V11I Neutral Neutral Q15067 I312M Neutral Neutral Q15067 T153I Neutral Disease A4UGR9 A2910T Neutral Neutral A4UGR9 P450A Neutral Neutral A4UGR9 R1626H Neutral Disease A4UGR9 I1488T Neutral Neutral A4UGR9 Y457H Neutral Neutral A4UGR9 V2607I Neutral Neutral A4UGR9 G2728D Neutral Neutral A4UGR9 S2553N Neutral Neutral A4UGR9 H2595Y Neutral Neutral A4UGR9 I1397T Neutral Neutral A4UGR9 L2423R Neutral Disease A4UGR9 Y2975C Neutral Neutral A4UGR9 N1833S Neutral Neutral A4UGR9 G3202E Neutral Disease A4UGR9 I3022V Neutral Neutral Q6NUQ4 V351M Neutral Neutral Q9GZT6 L10F Neutral Neutral Q13191 N883D Neutral Neutral Q13191 R584K Neutral Neutral Q13501 S399P Disease Neutral Q13501 M404T Disease Neutral Q13501 P392L Disease Neutral Q13501 M404V Disease Neutral Q13501 G411S Disease Disease Q13501 A117V Neutral Neutral Q13501 P387L Disease Neutral Q13501 G425R Disease Disease Q13501 E274Q Neutral Neutral P12694 G290R Disease Disease P12694 I326T Disease Disease P12694 Q190K Disease Disease P12694 A253T Disease Disease P12694 T151M Neutral Neutral P12694 F409C Disease Disease P12694 R159W Disease Disease P12694 Y413C Disease Disease P12694 Y438N Disease Disease P12694 P39H Neutral Neutral Q12908 A171S Neutral Neutral Q12908 T262M Disease Disease Q12908 L243P Disease Disease Q12908 V98I Neutral Neutral Q12908 V159I Neutral Neutral P03928 F21S Neutral Disease P03928 M28T Neutral Neutral P03928 L17P Neutral Disease P78383 R81H Neutral Neutral P07320 R15C Disease Disease P07316 R90T Neutral Disease P07320 E107A Disease Disease P07320 P24T Disease Neutral P07320 P24S Disease Neutral P11844 P148L Neutral Disease P53673 V36M Neutral Neutral P07315 F6L Neutral Disease P07315 T5P Disease Disease P53673 T84M Neutral Neutral P53673 L69P Disease Disease P07320 R59H Disease Disease P07316 L111I Neutral Neutral P07316 S73I Neutral Disease P07320 M102V Neutral Neutral P07315 R48H Neutral Neutral Q96C86 G73E Neutral Neutral P12319 K84R Neutral Neutral P12319 S101N Neutral Disease Q685J3 S1242T Neutral Neutral Q685J3 C1375R Neutral Neutral Q685J3 K227Q Neutral Neutral Q685J3 I1130T Neutral Neutral Q685J3 T1246S Neutral Neutral Q685J3 P1249A Neutral Neutral Q685J3 L1348P Neutral Neutral Q685J3 R4482Q Neutral Neutral Q685J3 G272E Neutral Neutral Q685J3 T982M Neutral Neutral Q685J3 T1246N Neutral Neutral Q685J3 R942S Neutral Neutral Q685J3 D4334N Neutral Neutral Q9Y275 A105T Neutral Neutral Q01432 N310K Disease Disease Q01432 R185W Neutral Neutral Q01432 V311L Disease Disease Q01432 Q712P Disease Disease Q01432 Y455H Neutral Neutral P23109 R388W Disease Disease Q01432 W450R Disease Disease Q01432 R402C Disease Disease P23109 R425H Disease Disease Q01432 M324T Disease Disease Q01432 R573C Disease Disease Q01432 R331C Disease Disease Q01432 P585L Disease Disease Q01432 A320V Disease Neutral Q8IYR0 G170A Neutral Neutral Q8IYR0 R154K Neutral Neutral P36957 P384T Neutral Disease P36957 A213P Neutral Neutral Q8N9R6 H122Q Neutral Neutral Q8N9R6 V73I Neutral Neutral P49759 S61F Neutral Neutral P49759 M440T Neutral Neutral Q9HAZ1 L352F Neutral Neutral P49759 R118G Neutral Neutral Q9HAZ1 I363V Neutral Neutral P49759 P307S Neutral Neutral Q9ULL8 D970G Neutral Disease Q9ULL8 S1089L Disease Neutral Q9UI42 G303C Neutral Disease Q96IY4 A169T Neutral Neutral Q9UI42 P157T Neutral Neutral Q8N4T0 S173C Neutral Neutral P48052 E80G Neutral Disease Q8WXQ8 P79S Neutral Neutral Q8N4T0 F45L Neutral Disease Q8WXQ8 L336S Neutral Neutral P15088 M171T Neutral Disease Q8WXQ8 E338D Neutral Neutral Q96IY4 T347I Neutral Neutral Q76LX8 R398H Disease Disease Q76LX8 C1024G Disease Disease Q76LX8 R268P Disease Disease Q76LX8 C508Y Disease Disease Q76LX8 R102C Disease Disease Q76LX8 R193W Disease Disease Q76LX8 A250V Disease Disease Q76LX8 G1239V Disease Neutral Q76LX8 T1226I Neutral Neutral Q76LX8 A1033T Neutral Neutral Q76LX8 H96D Disease Disease Q76LX8 A900V Neutral Neutral Q76LX8 W390C Disease Disease Q76LX8 P457L Neutral Neutral Q76LX8 I673F Disease Disease Q76LX8 C908Y Disease Disease Q76LX8 R1123C Disease Disease Q76LX8 Q456H Neutral Neutral Q76LX8 E740K Neutral Neutral Q76LX8 Q448E Neutral Neutral Q76LX8 S903L Neutral Neutral Q76LX8 H234Q Disease Disease Q76LX8 R528G Disease Disease Q76LX8 R1336W Disease Disease Q76LX8 C951G Disease Disease Q76LX8 T196I Disease Disease Q76LX8 R625H Neutral Neutral Q76LX8 C1213Y Disease Disease Q76LX8 R692C Disease Disease Q76LX8 V88M Disease Disease Q76LX8 G982R Neutral Disease Q3BBV0 V612M Neutral Neutral Q3BBV0 N31K Neutral Neutral Q3BBV0 A510T Neutral Neutral Q3BBV0 R663C Neutral Neutral Q3BBV0 K726E Neutral Neutral Q3BBV0 I20M Neutral Disease Q3BBV0 C591G Neutral Neutral Q3BBV0 H712D Neutral Neutral Q3BBV0 Q850K Neutral Disease Q3BBV0 Q734P Neutral Disease Q70CQ4 A552T Neutral Neutral Q70CQ4 D445Y Neutral Neutral Q70CQ4 I538T Neutral Neutral Q70CQ4 R931L Neutral Neutral Q70CQ4 Q532H Neutral Neutral O43294 Q129H Neutral Neutral Q16666 K202E Neutral Neutral Q16666 Y413N Neutral Neutral Q16666 R409S Neutral Neutral Q16666 S179T Neutral Neutral Q16666 D103H Neutral Neutral Q16666 T723S Neutral Neutral Q9H0E2 A222S Neutral Neutral A2RRH5 L133P Neutral Neutral A2RRH5 A697V Neutral Neutral A2RRH5 V393L Neutral Neutral A2RRH5 R437H Neutral Neutral A2RRH5 P470L Neutral Neutral P56378 I9V Neutral Neutral P12429 S19N Neutral Neutral P12429 I219N Neutral Disease P13928 A6S Neutral Neutral O76027 D166G Neutral Disease P12429 P251L Neutral Disease P12429 F291S Neutral Disease O76027 R225Q Neutral Disease Q9UJ72 M71L Neutral Neutral P13928 G177A Neutral Neutral P07355 V98L Neutral Neutral P06028 T84S Neutral Neutral P06028 T48M Neutral Neutral A6PVY3 I3S Neutral Neutral Q8NEM8 E122Q Neutral Neutral Q8NEM8 F45Y Neutral Neutral Q8NEM8 T360I Neutral Neutral P15516 R41Q Neutral Neutral Q8N3C0 C1800W Neutral Disease Q8N3C0 V1930M Neutral Disease Q8N3C0 V1050I Neutral Neutral Q8N3C0 S1995C Neutral Neutral Q8N3C0 Y2176C Neutral Neutral Q8N3C0 L146F Neutral Neutral A6NC98 D886A Neutral Neutral A6NC98 D193E Neutral Neutral A6NC98 W639R Neutral Neutral Q96NZ9 R101H Neutral Neutral Q96NZ9 G81S Neutral Neutral P31391 S321F Neutral Disease P31391 V284F Neutral Disease P31391 N83T Neutral Neutral P01135 V109M Neutral Neutral Q13137 V248A Neutral Neutral Q13137 P389A Neutral Neutral Q13137 G227R Neutral Neutral Q13137 T273A Neutral Neutral Q13137 G140E Neutral Neutral P20309 V65I Neutral Neutral Q9UPQ7 A783V Neutral Neutral Q9UPQ8 Y441S Disease Neutral Q9UPQ8 C99S Disease Disease Q7L513 R349Q Neutral Neutral Q9BZW2 F42L Neutral Neutral Q9BZW2 V332A Neutral Neutral Q13183 F254L Neutral Disease Q9BZW2 R277H Neutral Neutral Q9BZW2 N174S Neutral Neutral Q13183 V477M Neutral Disease Q13183 A310P Neutral Neutral Q9BZW2 V44I Neutral Neutral Q9BZW2 Q157E Neutral Neutral Q13183 I550V Neutral Neutral Q13183 P385S Neutral Disease Q9BZW2 Y205C Neutral Neutral Q9BZW2 I392T Neutral Neutral Q13183 L44F Neutral Neutral P68133 D288G Disease Disease P63261 K118M Disease Disease P68133 G270C Disease Disease P62736 H373P Neutral Disease P68133 N117S Disease Neutral P68133 I138M Disease Neutral P68133 D294V Disease Disease P68032 E101K Disease Disease P68133 M271R Disease Disease P68133 M134V Disease Disease P68133 E261V Disease Disease P68133 L96P Disease Disease P68133 V165L Disease Disease P62736 T320A Neutral Neutral P68133 V372F Disease Disease P68133 G17R Disease Disease P68133 N282K Disease Neutral P68133 Q265L Disease Disease P68032 A297S Disease Neutral P63261 T89I Disease Disease Q9H568 R245C Neutral Disease P63261 V370A Disease Neutral P60709 R183W Disease Disease P68133 P334S Disease Disease P68133 I359L Disease Disease P63261 P332A Disease Disease Q9H568 A3S Neutral Neutral P68133 H42Y Disease Disease P42025 V93A Neutral Neutral P68032 A333P Disease Neutral P63261 T278I Disease Neutral P68133 R258H Disease Disease P68133 R185G Disease Disease P63261 P264L Disease Disease P68133 G184D Disease Disease P68133 L223P Disease Disease Q8TDY3 G247R Neutral Disease P68032 R314H Disease Disease P68032 E363G Disease Disease P68133 R185C Disease Disease P62736 T196S Neutral Neutral P68032 P166A Disease Disease Q96DB9 H176R Neutral Neutral Q96DB9 S35A Neutral Neutral Q9Y5E7 G760D Neutral Neutral Q9NRJ7 R525Q Neutral Neutral Q9Y5E6 K41R Neutral Neutral Q9Y5E7 L674P Neutral Disease Q9UN66 K305E Neutral Neutral Q9NRJ7 G532S Neutral Disease Q9Y5E6 R414S Neutral Disease Q9Y5E3 Y747H Neutral Disease Q9UN66 F767L Neutral Disease Q9UN66 E244Q Neutral Neutral Q9Y5E2 E120K Neutral Disease Q9Y5E3 H636Q Neutral Disease Q9UN66 K199N Neutral Neutral Q9Y5E2 E187K Neutral Disease Q9Y5E3 V231I Neutral Neutral Q9Y5E2 V389L Neutral Neutral Q9Y5E4 I156T Neutral Neutral Q9Y5E7 V128I Neutral Neutral Q9Y5F1 T420I Neutral Neutral Q9UN66 A322V Neutral Neutral Q9Y5E3 L232F Neutral Neutral Q9Y5F2 Q4R Neutral Neutral Q9Y5E6 E207K Neutral Neutral Q9Y5E5 A421T Neutral Neutral Q00013 E448Q Neutral Neutral P52757 H204R Neutral Disease P09913 D352E Neutral Neutral Q8NDZ2 S221F Neutral Neutral Q8NDZ2 R772H Neutral Neutral Q8NDZ2 R463K Neutral Neutral P00492 G70E Disease Disease P00492 V8G Disease Neutral P00492 A50P Disease Disease P00492 D80V Disease Disease P00492 D201Y Disease Disease P00492 C206Y Disease Disease P00492 I132T Disease Disease P00492 M143K Disease Disease P00492 F74L Disease Disease P00492 L78V Disease Disease P00492 A50V Disease Disease P00492 I42F Disease Disease P00492 R45K Disease Disease P00492 L131S Disease Disease P00492 H204R Disease Disease P00492 V53M Disease Disease P00492 H204D Disease Disease P00492 T168I Disease Neutral P00492 D20V Disease Disease P00492 V53A Disease Disease P00492 V130D Disease Disease P00492 S104R Disease Disease P00492 M57T Disease Disease P00492 G58R Disease Disease P00492 M54L Disease Neutral P00492 I42T Disease Disease P00492 I132M Disease Disease P00492 F199V Disease Disease P00492 D177V Disease Disease P00492 P176L Disease Disease P00492 G71R Disease Disease P00492 R51P Disease Disease P00492 D201N Disease Neutral P00492 R51G Disease Disease P00492 D194E Disease Disease P00492 A161S Disease Neutral P00492 G16S Disease Disease P00492 D194N Disease Disease P00492 R48H Disease Disease P00492 D135G Disease Disease P00492 D201G Disease Disease P00492 G7D Disease Neutral P00492 S162R Disease Disease P00492 D177Y Disease Disease P00492 L41P Disease Disease P00492 S110L Disease Disease P00492 I183T Disease Disease P00492 G16D Disease Disease P00492 Y195C Disease Disease P18507 K328M Disease Disease P24046 H21R Neutral Neutral P18507 R82Q Disease Disease P18507 R177G Disease Disease Q99928 T352A Neutral Neutral Q8NC24 Q283E Neutral Neutral Q8NC24 G196R Neutral Neutral Q8NC24 L133I Neutral Neutral Q8NC24 S128P Neutral Neutral P56851 L5V Neutral Neutral P82921 R51Q Neutral Neutral Q13772 C350R Neutral Disease Q13772 P474R Neutral Neutral Q13772 F154L Neutral Disease Q13772 S94L Neutral Neutral Q13772 L561P Neutral Disease Q8TA86 H137L Disease Disease Q8TA86 K210R Neutral Neutral Q8TA86 D170G Disease Neutral P43235 G146R Disease Disease P43235 A277V Disease Disease P43235 L309P Disease Disease P43235 G79E Disease Disease P25774 R113W Neutral Neutral P25774 S161T Neutral Neutral Q9Y3C8 Y90C Neutral Disease O75306 P352A Neutral Neutral O75306 P20T Neutral Neutral O75306 P229A Neutral Neutral Q13323 E19K Neutral Neutral Q13323 L148P Neutral Disease Q7Z3S7 R863H Neutral Neutral Q7Z3S7 V327I Neutral Neutral Q7Z3S7 T869M Neutral Neutral Q6ZN55 R332Q Neutral Neutral Q6ZN55 R785Q Neutral Neutral Q9H3D4 P279H Disease Neutral Q9H3D4 D351H Disease Disease Q9H3D4 R243W Disease Disease Q9H3D4 R318H Disease Disease Q9H3D4 R319H Disease Disease Q9H3D4 R319C Disease Disease Q9H3D4 R337Q Disease Disease Q9H3D4 R266Q Disease Disease Q9H3D4 I549T Disease Neutral Q9H3D4 C345R Disease Disease Q9H3D4 R343W Disease Disease Q9H3D4 P348S Disease Disease Q9H3D4 C308Y Disease Disease Q9H3D4 Q204L Disease Disease Q9H3D4 D351G Disease Disease Q9H3D4 A187P Disease Disease Q9H3D4 R319S Disease Disease Q9H3D4 C347S Disease Disease Q9H3D4 D603H Neutral Neutral Q9H3D4 S560A Disease Neutral Q9H3D4 R243Q Disease Disease Q9H3D4 R318Q Disease Disease Q9H3D4 S580P Disease Neutral Q9H3D4 S129L Neutral Neutral Q9H3D4 K232E Disease Disease Q9H3D4 K233E Disease Disease Q9H3D4 S311N Disease Disease Q9H3D4 R318C Disease Disease Q9H3D4 S184L Disease Disease Q9H3D4 R343Q Disease Disease P22102 L21F Neutral Disease P22102 V421I Neutral Neutral P22102 D752G Neutral Neutral Q2NKJ3 V820I Neutral Neutral Q2NKJ3 V1005I Neutral Neutral Q9H4I9 R46G Neutral Neutral Q6GPH6 G280R Neutral Neutral Q6GPH6 S428C Neutral Neutral Q6GPH6 T463M Neutral Neutral Q9BQN1 R621Q Neutral Neutral Q14CZ8 M218V Neutral Neutral Q9H0M4 T153A Neutral Neutral O15013 V700I Neutral Neutral O15013 T357I Disease Neutral Q9HBG4 R807Q Disease Disease Q9HBG4 P524L Disease Disease Q13488 D517N Disease Disease Q9HBG4 A2V Neutral Neutral Q9HBG4 G175D Disease Disease Q9HBG4 R449H Disease Disease Q13488 R444L Disease Disease Q13488 A141P Disease Disease Q9HBG4 G820R Disease Disease Q13488 P775R Disease Neutral Q9HBG4 M580T Disease Disease Q13488 G405R Disease Disease P35221 A179V Neutral Neutral P35221 P219S Neutral Neutral Q7L5N7 M163I Neutral Neutral Q16584 A282G Neutral Neutral Q16584 P252H Neutral Neutral Q16584 D151V Neutral Disease Q8WXD5 G140D Neutral Neutral P22674 L161M Neutral Neutral Q9Y4X3 I78V Neutral Neutral Q9Y4X3 L96F Neutral Neutral Q6UXD7 S170P Neutral Disease P02735 G15S Neutral Neutral Q6W2J9 P85L Disease Disease P18509 D54G Neutral Neutral Q9Y227 K354E Neutral Neutral Q9NQZ7 V276A Neutral Neutral Q8WV44 D438G Neutral Disease Q8WV44 A78T Neutral Neutral P20273 Y639H Neutral Neutral P20273 E203K Neutral Neutral P20273 G745D Neutral Neutral P20273 A34T Neutral Disease P20273 R669C Neutral Disease P20273 S664G Neutral Neutral O43731 V199G Neutral Disease Q9UFD9 R1419C Neutral Neutral P55058 M425I Neutral Neutral P55058 F444L Neutral Neutral P55058 R380W Neutral Neutral P55058 R282Q Neutral Neutral P55058 R372H Neutral Neutral P55058 T487K Neutral Neutral P55058 S124Y Neutral Neutral Q8TBY8 E193K Neutral Neutral Q8TBY8 A172T Neutral Neutral Q8TBY8 R381L Neutral Neutral Q8TBY8 K650T Neutral Neutral P43246 P622L Disease Disease P43246 D660G Disease Neutral P43246 C199R Disease Disease P43246 T8M Neutral Neutral P43246 L390F Neutral Disease P43246 V161D Disease Disease P43246 G322D Neutral Disease P43246 R96H Neutral Disease P43246 T807S Neutral Neutral P43246 N835H Neutral Disease P43246 Y43C Neutral Disease P43246 N127S Neutral Disease P43246 H639Y Disease Disease P43246 R524P Disease Disease P43246 M688I Disease Disease P43246 I216V Disease Neutral P43246 A636P Disease Disease P43246 G692R Disease Disease P43246 M779I Neutral Neutral P43246 S323C Disease Neutral P43246 K845E Disease Neutral P43246 E562V Disease Neutral P43246 T905R Disease Neutral P43246 I145M Neutral Neutral P43246 C697R Disease Disease P43246 C697F Disease Disease P43246 L911R Neutral Disease P43246 N596S Neutral Neutral P43246 I770V Neutral Neutral P43246 R106K Neutral Neutral P43246 S554R Disease Disease P43246 V163G Disease Disease P43246 G674S Disease Disease P43246 H46Q Disease Disease P43246 A305T Disease Disease P43246 A834T Disease Disease P43246 C641G Neutral Neutral P43246 D167H Neutral Disease P43246 N139S Disease Disease P43246 P670L Neutral Disease Q8N0T5 L93S Neutral Neutral Q8N0T5 L11F Neutral Neutral Q8N0T5 S60P Neutral Neutral P04003 Y357H Neutral Neutral P04003 I300T Neutral Neutral P04003 W473L Neutral Disease Q3YBM2 T70A Neutral Neutral Q3YBM2 R94S Neutral Neutral Q3YBM2 P55S Neutral Neutral Q3YBM2 A134T Neutral Neutral Q3YBM2 R180W Neutral Neutral Q15735 S333I Neutral Neutral O15056 E1468G Neutral Neutral Q6ZRI0 S691P Neutral Neutral Q6ZRI0 W2908S Neutral Neutral Q6ZRI0 A918T Neutral Neutral Q6ZRI0 R2749Q Neutral Neutral Q6ZRI0 A1398G Neutral Neutral Q6ZRI0 R1074Q Neutral Neutral Q6ZRI0 T374S Neutral Neutral Q6ZRI0 A1831V Neutral Neutral Q6ZRI0 T658M Neutral Neutral Q6ZRI0 A1111V Neutral Disease Q6ZRI0 P1646L Neutral Neutral Q6ZRI0 P1128L Neutral Disease Q6ZRI0 T1946M Neutral Neutral P00966 T119I Disease Disease P00966 R279Q Disease Disease P00966 A118T Disease Disease P00966 R363G Disease Disease P00966 P96S Disease Disease P00966 E191K Disease Disease P00966 G117S Disease Disease P00966 V69A Disease Disease P00966 R363Q Disease Disease P00966 A192V Disease Disease P00966 R157C Disease Disease P00966 W179R Disease Disease P00966 R86C Disease Disease P00966 K310R Disease Disease P00966 R86H Disease Neutral P00966 E270Q Disease Disease P00966 G117D Disease Disease P00966 R95S Disease Disease P00966 S18L Disease Disease P00966 R108L Disease Disease P00966 R265H Disease Disease P00966 R363L Disease Disease P00966 G14S Disease Disease P00966 G324S Disease Disease P00966 E283K Disease Disease P00966 C19R Disease Disease P00966 T389I Disease Neutral P00966 R363W Disease Disease P00966 K310Q Disease Disease P00966 G390R Disease Disease P00966 S180N Disease Disease P00966 V269M Disease Disease P00966 G280R Disease Disease P00966 R157H Disease Disease P00966 R304W Disease Disease P00966 R272C Disease Disease P00966 G362V Disease Disease Q5JUK9 N35D Neutral Neutral Q5JUK9 G53S Neutral Neutral Q5SNV9 W782R Neutral Neutral Q5SNV9 R944H Neutral Neutral Q5SNV9 R1215H Neutral Neutral Q5SNV9 P453S Neutral Neutral Q5SNV9 C1295S Neutral Neutral Q5SNV9 W955R Neutral Neutral Q5SNV9 R602W Neutral Neutral Q5SNV9 R544Q Neutral Neutral Q5SNV9 S848I Neutral Neutral Q5SNV9 R800C Neutral Neutral Q5SNV9 R1451G Neutral Neutral O43432 P496A Neutral Neutral Q6ZWT7 T501A Neutral Neutral Q7Z3U7 A548T Neutral Neutral Q6UXH1 D182E Neutral Neutral Q6UXH1 E325G Neutral Neutral Q6UXH1 S295A Neutral Neutral P00739 D339H Neutral Neutral Q9UHG0 S221G Neutral Neutral Q9BTP7 I192T Neutral Neutral Q9BTP7 S158L Neutral Neutral Q66K79 P5L Neutral Neutral Q66K79 T501M Neutral Neutral Q8TC71 S227P Neutral Neutral Q8TC71 K483R Neutral Neutral Q6T4P5 A690V Neutral Neutral Q6T4P5 I193T Neutral Neutral Q9P225 T3600I Neutral Neutral Q9P225 S312T Neutral Disease Q9P225 A100V Neutral Neutral Q9P225 E1326G Neutral Disease Q9P225 R2548H Neutral Neutral Q6RW13 A143V Neutral Neutral P27695 Q51H Neutral Neutral P27695 I64V Neutral Neutral P27695 D148E Neutral Neutral Q9H221 M655V Neutral Disease Q9H221 G575R Neutral Disease Q9H221 R405H Disease Disease Q9H221 Y641F Neutral Neutral Q9H221 T400K Neutral Neutral Q9H221 D19H Neutral Neutral Q9H221 L572P Disease Disease Q9H221 E238K Neutral Disease Q9H221 P231T Disease Neutral Q9H221 A259V Neutral Disease Q9H221 G574R Disease Disease Q9H221 Y54C Neutral Disease Q9H221 R184H Disease Disease Q9H221 L501P Disease Disease Q9H221 R543S Disease Neutral Q9H221 V632A Neutral Neutral Q9H221 V210M Neutral Disease Q9H221 G574E Disease Disease Q9H221 R263Q Disease Disease Q9H221 L596R Disease Disease Q9H227 D106N Neutral Neutral Q9H227 R213P Neutral Disease Q9H227 C354R Neutral Neutral P14598 D166N Neutral Neutral P14598 R90H Neutral Disease P14598 K258E Neutral Disease P14598 R42Q Disease Disease P14598 G262S Neutral Disease P14598 S99G Neutral Neutral P14598 T160S Neutral Neutral P14598 A308V Neutral Neutral Q7L4I2 H88R Neutral Neutral Q9Y2W1 A201V Neutral Neutral Q5T5S1 D129A Neutral Neutral Q5T5S1 T421N Neutral Neutral Q5T5S1 L113R Neutral Disease Q5T5S1 R342W Neutral Neutral Q5T5S1 M38T Neutral Neutral O43374 R432P Neutral Disease O95294 T58M Neutral Neutral O43374 Y731C Neutral Disease O95294 H321R Neutral Neutral O95294 V11L Neutral Neutral O43374 M352V Neutral Neutral O95295 S112C Neutral Neutral Q6PEW0 S182G Neutral Neutral Q6PEW0 V240I Neutral Neutral Q6PEW0 T295A Neutral Neutral Q9C056 V209A Neutral Neutral Q969H9 S51A Neutral Neutral Q8N9Y4 A28T Neutral Neutral Q9BRB3 T14A Neutral Neutral Q06432 G196S Neutral Neutral Q9Y2Q0 T673M Neutral Neutral Q96EY8 R19H Neutral Neutral Q96EY8 R19Q Neutral Neutral Q96EY8 R191W Disease Disease Q96EY8 M239K Neutral Neutral Q96EY8 I96T Disease Disease Q96EY8 R186W Neutral Disease Q96EY8 A135T Disease Neutral Q96EY8 E193K Disease Disease Q6IQ20 S152A Neutral Neutral Q6IQ20 D389N Neutral Neutral Q8IYI0 A23V Neutral Neutral Q99959 S140F Disease Neutral Q99959 C796R Disease Disease Q99959 S615F Disease Disease Q99959 K654Q Disease Disease Q6ZWJ8 G47E Neutral Neutral Q96LU7 A118S Neutral Neutral Q96LU7 M210L Neutral Neutral Q96LU7 S88L Neutral Neutral Q86XL3 Y122H Neutral Neutral Q86XL3 Q148E Neutral Neutral Q86XL3 H720R Neutral Neutral Q5TEA6 H687Q Neutral Neutral Q9P267 S677N Neutral Neutral Q86WV6 R71H Neutral Neutral Q86WV6 R293Q Neutral Neutral Q86WV6 H232R Neutral Neutral Q16270 L11F Neutral Neutral O95954 R299P Disease Disease O95954 R135C Disease Disease O95954 A438E Neutral Neutral P35613 G269V Neutral Neutral O76095 L16F Neutral Neutral Q53T94 E462D Neutral Neutral Q53T94 V282I Neutral Neutral Q53T94 T487M Neutral Neutral Q53T94 T351A Neutral Neutral Q53T94 A6S Neutral Neutral Q9UJY1 K141N Disease Disease Q9UJY1 K141E Disease Disease Q7RTS9 E87K Disease Neutral Q7RTS9 N469Y Disease Disease Q7Z7A1 P216L Neutral Neutral Q7Z7A1 V56I Neutral Neutral Q7Z7A1 A889T Neutral Neutral Q6PIU1 D22G Neutral Neutral Q15654 L296F Neutral Disease Q8NHQ1 S135N Neutral Neutral P38935 V275I Neutral Neutral P38935 E334K Disease Neutral P38935 R694W Neutral Neutral P38935 S201L Neutral Neutral P38935 H213R Disease Disease P38935 V580I Disease Disease P38935 E928K Neutral Disease P38935 L192P Disease Disease P38935 T671A Neutral Neutral P38935 T879K Disease Neutral P38935 C241R Disease Disease P38935 L426P Disease Disease P38935 L364P Disease Disease P38935 R603H Disease Disease P38935 R637C Disease Disease P38935 D974E Disease Neutral P38935 G586C Disease Disease P38935 L361P Disease Disease P38935 D565N Disease Disease P38935 L577P Disease Disease P38935 T221A Disease Disease P38935 N583I Disease Disease P38935 E514K Disease Disease P38935 E382K Disease Disease P08571 N204D Neutral Neutral P27987 P552Q Neutral Neutral P27987 S408A Neutral Neutral Q96RL7 Y2721C Disease Disease Q96RL7 S1452P Disease Neutral Q96RL7 I90K Disease Disease Q6DN72 S427G Neutral Neutral Q5M9Q1 H162Y Neutral Neutral Q5M9Q1 Y96C Neutral Disease Q5M9Q1 G398E Neutral Neutral Q5M9Q1 T152N Neutral Neutral Q8WVC6 N84I Neutral Disease Q8N6W0 F65L Neutral Disease Q96J87 R152P Neutral Disease Q9GZU1 D362Y Disease Disease Q9GZU1 T232P Disease Disease Q9GZU1 R403C Disease Disease Q9GZU1 F465L Disease Disease Q9GZU1 V446L Disease Disease Q9GZU1 L106P Disease Disease Q9GZU1 L447P Disease Disease O75074 V708A Neutral Neutral Q86WR7 A412V Neutral Neutral Q8N726 P58S Neutral Neutral Q16378 R120Q Neutral Neutral Q16378 R96Q Neutral Neutral O95218 R207G Neutral Neutral P08684 T363M Neutral Disease P08684 M445T Neutral Neutral P20815 I488T Neutral Disease P08684 S222P Neutral Disease P20815 A337T Neutral Neutral P08684 D174H Neutral Disease P08684 G56D Neutral Disease P08684 R162Q Neutral Disease Q9HB55 P340A Neutral Neutral P08684 K96E Neutral Disease P08684 P416L Neutral Disease P08684 S252A Neutral Neutral P24462 R409T Neutral Neutral P20815 I371V Neutral Neutral P20815 R28C Neutral Disease P08684 L373F Neutral Neutral P08684 T185S Neutral Neutral P08684 L15P Neutral Disease P08684 P218R Neutral Disease P08684 L293P Neutral Disease P08684 R130Q Neutral Disease P08684 I431T Neutral Neutral P20815 Q200R Neutral Neutral P20815 F446S Neutral Disease P08684 F189S Neutral Neutral P08684 P467S Neutral Neutral P20815 H30Y Neutral Neutral P08684 T349N Neutral Neutral P08684 V170I Neutral Neutral P08684 I118V Neutral Neutral P20815 T398N Neutral Neutral P20815 D277E Neutral Neutral Q92904 T12A Neutral Neutral Q92904 T54A Disease Neutral Q8IYS1 K333E Neutral Neutral O43602 L85S Disease Disease O43602 R238H Disease Disease O43602 T264I Disease Neutral O43602 G265E Disease Disease O43602 Y167D Disease Disease O43602 T84I Disease Disease O43602 S89R Disease Neutral O43602 G142A Disease Disease O43602 A113S Disease Disease O43602 L139R Disease Disease O43602 A293S Disease Disease O43602 R220C Disease Disease O43602 D128H Disease Neutral O43602 N242K Disease Disease O43602 R220L Disease Disease O43602 R144S Disease Disease O43602 I292N Disease Disease O43602 Y167H Disease Disease O43602 T245A Disease Disease O43602 N242I Disease Disease O43602 I146T Disease Disease O43602 P233L Disease Disease O43602 G109E Disease Disease O43602 V278I Disease Neutral O43602 A293V Disease Disease O43602 R131G Disease Disease O43602 F285L Disease Neutral O43602 R101H Disease Disease O43602 R101L Disease Disease O43602 I256T Disease Disease O43602 I292T Disease Disease O43602 D104N Disease Disease O43602 G265V Disease Disease O43602 G295D Disease Disease O43602 K92N Disease Neutral O43602 R228C Disease Disease O43602 T245R Disease Disease O43602 P233R Disease Disease O43602 R120L Disease Disease O43602 R234W Disease Disease O43602 N102D Disease Disease P51648 G185A Disease Disease P30838 G309E Neutral Disease P51648 V64D Disease Disease P51648 L106R Disease Disease P51648 S415N Disease Neutral P51648 F419S Disease Disease P51648 G406R Disease Disease P51648 M328I Disease Disease P51648 P121L Disease Disease P51648 I45F Disease Disease P51648 T184R Disease Disease P51648 R423H Disease Disease P51648 R228C Disease Neutral P51648 C237Y Disease Disease P30838 A134S Neutral Disease P51648 K266N Disease Neutral P51648 K447E Disease Disease P51648 D245N Disease Neutral P51648 C226W Disease Disease P51648 C214Y Disease Disease P51648 N386S Disease Disease P51648 T184M Disease Disease P51648 H411Y Disease Disease P51648 G412R Disease Disease P51648 P114L Disease Disease P51648 S365L Disease Neutral P51648 P315S Disease Disease P51648 Y279N Disease Neutral P30838 P329A Neutral Neutral P49914 T202A Neutral Neutral Q9H1C7 C90S Neutral Neutral Q99638 M307T Neutral Neutral Q99638 S100A Neutral Neutral Q99638 C3F Neutral Neutral Q99638 H239R Neutral Neutral Q8TB36 R282C Disease Disease Q8TB36 R120Q Disease Neutral Q8TB36 R310Q Disease Neutral Q8TB36 R161H Disease Disease P62917 I98V Neutral Neutral Q5FWE3 Q138E Neutral Neutral Q5FWE3 L860I Neutral Neutral Q15398 G69E Neutral Neutral Q8IV42 G206R Neutral Neutral P20849 Q621R Neutral Neutral P20849 K870R Neutral Neutral P20849 S339P Neutral Neutral P20849 L882V Neutral Neutral Q05329 G326A Neutral Disease Q05329 K124N Neutral Disease Q99259 S12C Disease Neutral Q05329 P153Q Neutral Disease Q99259 V474G Neutral Disease Q05329 G232E Neutral Disease Q05329 G12R Neutral Neutral Q99259 I228L Neutral Neutral Q99259 R532Q Neutral Neutral Q99259 F565L Neutral Disease Q05329 K286R Neutral Neutral Q05329 R375Q Neutral Disease Q8NDB2 R650C Neutral Neutral Q8NDB2 A383T Neutral Neutral Q8NDB2 R61H Neutral Neutral Q96GY0 A156T Neutral Neutral P01127 I88V Neutral Neutral Q9BSK1 R350S Neutral Neutral Q99467 N53K Neutral Neutral Q99467 S99R Neutral Neutral Q14966 V1726M Neutral Neutral Q14966 I110V Neutral Neutral Q14966 N980S Neutral Neutral Q14966 A1912V Neutral Neutral Q8NEN0 M166T Neutral Neutral Q8NEN0 N433D Neutral Neutral O43435 F148Y Disease Neutral O43435 G310S Disease Neutral O43435 H194Q Disease Neutral O15533 R260T Neutral Neutral Q13740 L315M Neutral Neutral Q13740 T301M Neutral Neutral Q13740 V352M Neutral Neutral Q13740 G229D Neutral Disease Q13740 N258S Neutral Neutral Q9BVJ6 V487A Neutral Neutral Q5TAP6 G85V Neutral Neutral Q5TAP6 T101A Neutral Neutral Q9H8X9 R341Q Neutral Neutral Q9H8X9 R372H Neutral Neutral Q53GL0 P21A Neutral Neutral Q6SJ93 P731A Neutral Neutral P52743 R112Q Neutral Neutral P52743 Q181H Neutral Neutral O94812 D582A Neutral Neutral Q12768 N471D Disease Neutral Q12768 L619F Disease Neutral Q12768 V626F Disease Disease P01730 R265W Neutral Neutral P01730 K191E Neutral Neutral P01730 F227S Neutral Disease Q969Z4 A332V Neutral Neutral O95995 E199K Neutral Neutral Q9HBB8 D389N Neutral Neutral Q9HBB8 S357R Neutral Neutral Q5T6F0 R131Q Neutral Neutral Q5VU92 D19G Neutral Neutral P09132 A4T Neutral Neutral Q9NVR5 D259G Neutral Neutral Q13163 A427V Neutral Neutral Q13163 H118R Neutral Neutral O94833 L2011V Neutral Neutral O94833 N1319K Neutral Neutral O94833 H1116Y Neutral Neutral P07204 P501L Neutral Neutral P07204 G79A Neutral Neutral P07204 D486Y Disease Neutral P07204 P495S Neutral Neutral P07204 A43T Neutral Neutral P07204 A473V Neutral Neutral Q8N720 E52D Neutral Disease Q9NZW4 Y6D Disease Disease Q9NZW4 P17T Disease Disease Q9NZW4 V18F Disease Disease Q8IUG1 G92R Neutral Neutral Q8IUG1 C34S Neutral Disease Q8NDY8 M141T Neutral Neutral Q9UKI8 R121C Neutral Neutral Q9Y276 R144Q Disease Neutral Q9Y276 V353M Disease Neutral Q9Y276 R306H Disease Neutral Q9Y276 P99L Disease Disease Q9Y276 V327A Disease Neutral Q9Y276 S78G Disease Neutral Q9Y276 R184C Disease Disease Q9Y276 R45C Disease Disease Q9Y276 R183H Disease Disease Q9Y276 R114W Disease Disease Q9Y276 S277N Disease Neutral Q9Y276 Q302E Disease Disease Q9Y276 R155P Disease Disease Q9Y276 G35R Disease Disease Q96PE2 G450E Neutral Neutral Q96PE2 A1465D Neutral Neutral Q99814 G537W Disease Neutral O75333 K101T Neutral Disease Q5JPH6 S457G Neutral Neutral P57052 L116V Neutral Neutral O75570 N2S Neutral Neutral O75570 L324V Neutral Disease Q8IZY2 T319A Neutral Neutral Q8IZY2 Q1686R Neutral Neutral Q8IZY2 R1349Q Neutral Neutral Q8IZY2 G1527A Neutral Neutral Q8IZY2 R463H Neutral Neutral Q8IZY2 E188G Neutral Neutral Q8IZY2 N718T Neutral Disease Q8IZY2 H395R Neutral Neutral Q8IZY2 A2045S Neutral Neutral P10082 T72R Neutral Neutral P07954 G282V Disease Disease P07954 R233H Disease Disease P07954 M328R Disease Disease P07954 N107T Disease Disease P07954 F312C Disease Disease P07954 H180R Disease Disease P07954 Q185R Disease Disease P07954 A308T Disease Disease P07954 D425V Disease Disease P07954 A117P Disease Disease P07954 K230R Disease Disease Q14690 D1871A Neutral Neutral Q14690 A623S Neutral Neutral Q14690 L1216F Neutral Neutral P31268 T18A Neutral Neutral Q9NP78 V121M Neutral Neutral Q14191 K125N Disease Neutral Q14191 K135E Disease Disease Q8IVL0 A45T Neutral Neutral Q8IVL1 K109R Neutral Neutral Q8IVL1 E1041D Neutral Neutral Q8IVL1 V2374I Neutral Neutral Q8IVL0 S210W Neutral Neutral Q8IVL1 Q491H Neutral Neutral Q8IVL1 A1077P Neutral Neutral O15553 T267I Disease Neutral O15553 H478Y Disease Neutral O15553 L649P Disease Disease O15553 L110P Disease Neutral O15553 M680L Disease Neutral O15553 G678E Disease Disease O15553 E167D Disease Neutral O15553 E656A Disease Disease O15553 K695M Disease Neutral O15553 E230K Disease Neutral O15553 S108R Disease Neutral O15553 K695R Disease Neutral O15553 M680I Disease Neutral O15553 R408Q Disease Neutral O15553 E163A Disease Neutral O15553 P646L Disease Disease O15553 M694V Disease Disease O15553 E148Q Disease Neutral O15553 P758S Disease Disease O15553 R761H Disease Neutral O15553 V704I Disease Neutral O15553 E474K Disease Neutral O15553 E319K Disease Neutral O15553 F743L Disease Disease O15553 M694I Disease Disease O15553 R653H Disease Neutral O15553 F585L Neutral Neutral O15553 P780T Disease Neutral O15553 I591T Disease Neutral O15553 T177I Disease Neutral O15553 D661N Disease Neutral O15553 S675N Disease Neutral O15553 P369S Disease Neutral O15553 G632S Disease Neutral O15553 E148V Disease Neutral O15553 R42W Disease Neutral O15553 T681I Disease Neutral O15553 V726A Disease Neutral O15553 M694L Disease Neutral O15553 F479L Disease Neutral O15553 I641F Disease Neutral O15553 I720M Disease Disease O15553 A744S Disease Neutral O15553 Q440E Neutral Neutral O15553 P705S Disease Neutral O15553 I640M Disease Neutral O15553 R202Q Neutral Neutral O15553 Y688C Disease Disease Q8WXG1 L42R Neutral Neutral P10768 G190E Neutral Disease P10768 G257D Neutral Disease P06737 R715S Neutral Disease P06737 V222I Neutral Neutral P06737 R425P Neutral Disease P11217 R602W Disease Disease P11217 G686R Disease Disease P06737 I806L Neutral Disease P11217 E655K Disease Disease P11216 D502N Neutral Neutral P11217 G205S Disease Disease P11217 Q666E Disease Disease P06737 N377K Disease Disease P11217 L397P Disease Disease P11217 A704V Disease Neutral P11217 A687P Disease Disease P06737 N339S Disease Disease P11216 A303S Neutral Disease P11217 N685Y Disease Disease P11217 R194W Disease Disease P06737 V231E Neutral Disease P11217 E349K Disease Disease P11217 K543T Disease Disease P11217 T488N Disease Disease P11217 W798R Disease Disease P11217 L116P Disease Disease P06737 V698G Neutral Disease P11217 L292P Disease Disease P11217 A660D Disease Disease Q5R387 Q140R Neutral Neutral Q8TF08 H26Q Neutral Neutral P98174 R610Q Disease Disease P98174 E380A Disease Disease P98174 R443H Disease Disease P98174 S205I Disease Neutral P98174 R522H Disease Neutral P98174 P312L Disease Neutral O14836 C104R Disease Disease O14836 A181G Disease Neutral O14836 R202H Disease Neutral P15814 P142L Disease Disease P55211 E114D Neutral Neutral P55211 G176R Neutral Disease P55211 S99L Neutral Neutral P55211 I185M Neutral Neutral P55211 L106V Neutral Neutral P55211 R173H Neutral Neutral P55211 R192C Neutral Disease P55211 Q221R Neutral Neutral P55211 A28V Neutral Neutral P55211 T102I Neutral Neutral Q12864 E739A Neutral Neutral Q12864 I446T Neutral Neutral O75309 H257Y Neutral Neutral O75309 L191F Neutral Neutral Q12864 D734E Neutral Disease Q12866 I871T Disease Neutral Q12866 E540K Disease Neutral Q12866 S661C Disease Neutral Q99728 C557S Neutral Neutral Q99728 Q564H Disease Disease Q99728 R378S Neutral Neutral Q99728 P24S Neutral Neutral Q99728 S241C Neutral Neutral Q99728 C645R Neutral Neutral Q99728 R658C Neutral Neutral Q99728 V695L Disease Neutral Q99728 S186G Neutral Neutral Q99728 S728F Neutral Disease Q99728 V507M Neutral Neutral Q99728 S761N Disease Neutral Q53H76 S284N Neutral Disease Q53H76 S23I Neutral Neutral Q53H76 R110H Neutral Neutral P10746 P53L Disease Neutral P10746 A104V Disease Neutral P10746 V82F Disease Neutral P10746 G188W Disease Neutral P10746 Y19C Disease Disease P10746 G188R Disease Neutral P10746 L4F Disease Neutral P10746 T62A Disease Disease P10746 T228M Disease Disease P10746 G225S Disease Disease P10746 I129T Disease Disease P10746 A66V Disease Neutral P10746 S47P Disease Neutral P10746 A69T Disease Disease P10746 I219S Disease Disease P10746 S212P Disease Neutral P10746 V3F Disease Neutral P10746 C73R Disease Disease P10746 V99A Disease Disease Q8WXE9 S851A Neutral Neutral Q8WXE9 S307P Neutral Neutral Q9H0W5 K507N Neutral Neutral O15213 V341A Neutral Disease Q5VTT5 G662R Neutral Disease P54296 E81K Neutral Neutral Q5VTT5 I1066T Neutral Neutral P54296 L321V Neutral Neutral Q5VTT5 P853S Neutral Neutral Q5VTT5 D892A Neutral Neutral P54296 T776M Neutral Neutral Q5VTT5 D528G Neutral Neutral Q5VTT5 F1041L Neutral Neutral P54296 T182M Neutral Neutral P54296 S601Y Neutral Neutral P54296 V701I Neutral Neutral Q5VTT5 Q435R Neutral Disease Q5VTT5 R775Q Neutral Neutral P54296 E1284D Neutral Neutral Q5VTT5 R1124Q Neutral Neutral Q5VTT5 M344T Neutral Neutral Q5VTT5 T266M Neutral Neutral P54296 V363I Neutral Neutral P54296 L1022F Neutral Neutral Q9Y4B4 F1369L Neutral Neutral P01374 T60N Neutral Neutral P01374 H51P Neutral Disease P01374 T125P Neutral Neutral P01374 C13R Neutral Neutral Q99706 H371N Neutral Neutral Q99706 A209P Neutral Neutral Q99706 Y53C Neutral Disease Q99706 L87V Neutral Neutral Q99706 D271N Neutral Neutral Q99706 T138A Neutral Neutral Q16558 E65K Neutral Neutral Q9UBK2 T612M Neutral Neutral Q9UBK2 G482S Neutral Neutral P35914 D42E Disease Disease P35914 D42H Disease Disease P35914 H233R Disease Disease P35914 E279K Disease Disease P35914 D42G Disease Disease P35914 R41Q Disease Disease P35914 V70L Disease Neutral P09544 R299W Neutral Disease O14905 T106M Neutral Neutral O00755 R292C Disease Disease P09544 L5R Neutral Neutral P56705 E216G Disease Disease O00755 A109T Disease Disease P16403 A18V Neutral Neutral Q02809 W612C Disease Disease Q02809 H706R Disease Disease O60568 R286W Neutral Neutral Q02809 G678R Disease Disease O00469 R598H Disease Disease O00469 T608I Disease Disease O00469 G601V Disease Disease Q02809 W446G Disease Disease Q02809 A667T Disease Disease Q9P242 T205A Neutral Neutral Q9P242 P586T Neutral Neutral Q9BY42 V171M Neutral Neutral Q9BY42 T159A Neutral Neutral Q9NVL1 P30R Neutral Neutral Q9NVL1 S7A Neutral Neutral Q9NVL1 A70V Neutral Neutral Q9UBM7 S169L Disease Disease Q9UBM7 G410S Disease Disease Q9UBM7 K198E Disease Neutral Q9UBM7 R242C Disease Disease Q9UBM7 G244R Disease Disease Q9UBM7 A247V Disease Neutral Q9UBM7 R443C Disease Disease Q9UBM7 G138V Disease Disease Q9UBM7 I145L Disease Neutral Q9UBM7 H119L Disease Neutral Q9UBM7 R450L Disease Disease Q9UBM7 R362C Disease Disease Q9UBM7 R404S Disease Disease Q9UBM7 R352Q Disease Disease Q9UBM7 F255L Disease Neutral Q9UBM7 V281M Disease Disease Q9UBM7 E448K Disease Disease O76062 T299I Neutral Neutral Q9UBM7 L68P Disease Disease Q9UBM7 S113C Disease Neutral Q9UBM7 L157P Disease Disease Q9UBM7 G147D Disease Disease Q9UBM7 S397L Disease Disease Q9UBM7 R446Q Disease Disease Q9UBM7 W182L Disease Disease Q9UBM7 L109P Disease Disease Q9UBM7 T154M Disease Disease Q9UBM7 W248C Disease Disease Q9UBM7 C183Y Disease Disease Q9UBM7 R352W Disease Disease Q9UBM7 T93M Disease Neutral Q9UBM7 W182C Disease Disease Q9UBM7 V326L Disease Neutral Q9UBM7 F235S Disease Disease Q9UBM7 C380Y Disease Disease Q9UBM7 R242H Disease Disease Q9UBM7 G410R Disease Disease Q9UBM7 C311Y Disease Disease Q9UBM7 Q107H Disease Disease Q9UBM7 P51S Disease Disease Q9UBM7 C311G Disease Disease Q9UBM7 H405Y Disease Disease Q9UBM7 V353A Disease Neutral Q9UBM7 Y324H Disease Disease Q9UBM7 I297T Disease Disease Q9UBM7 C380R Disease Neutral Q9UBM7 H426P Disease Disease Q9UBM7 R404C Disease Disease Q9UBM7 T289I Disease Disease Q9UBM7 L99P Disease Disease Q9UBM7 C380S Disease Neutral Q9UBM7 G344R Disease Disease Q9UBM7 Y408H Disease Disease Q9UBM7 E448Q Disease Disease Q92838 D298H Disease Neutral Q92838 A349T Disease Neutral Q92838 G255C Disease Neutral Q92838 G255D Disease Neutral Q92838 R156H Disease Neutral Q92838 G299S Disease Neutral Q92838 G291R Disease Neutral Q92838 R65G Disease Disease Q92838 R156C Disease Neutral Q92838 H252Y Disease Neutral Q92838 R357P Disease Disease Q92838 R155C Disease Neutral Q92838 F302S Disease Disease Q92838 H252L Disease Neutral Q92838 C332Y Disease Disease Q92838 W274G Disease Disease Q92838 H54Y Disease Neutral Q92838 A356D Disease Disease Q92838 R69L Disease Neutral Q92838 E63K Disease Neutral Q92838 G224A Disease Neutral Q92838 G291W Disease Neutral Q92838 T378M Disease Neutral Q92838 P209L Disease Neutral Q92838 Y61H Disease Neutral Q92838 G269V Disease Disease Q92838 L55R Disease Disease Q92838 C60R Disease Neutral Q9UKZ9 P292T Neutral Disease Q8NFQ6 V269A Neutral Neutral Q8NFQ6 V302L Neutral Neutral Q8NFQ6 S451P Neutral Neutral Q06609 R150Q Disease Neutral Q14565 M200V Neutral Disease P41218 S156R Neutral Neutral P41218 H357Y Neutral Disease P41218 V286L Neutral Disease Q9H3R0 V1039I Neutral Neutral O75164 V877G Neutral Disease O75164 E482A Neutral Neutral Q9H3R0 Q767E Neutral Neutral Q9H3R0 D396N Neutral Neutral Q9H211 A135V Neutral Neutral Q9H211 A537V Neutral Neutral Q9H211 R172C Neutral Neutral Q9H211 E456A Neutral Neutral A1A5B4 R399C Neutral Disease A1A5B4 V391I Neutral Neutral Q587I9 R38G Neutral Neutral Q8N8Y2 E295K Neutral Neutral Q8N8Y2 G272R Neutral Neutral Q9Y4F4 L511V Neutral Neutral Q9Y4F4 E416Q Neutral Neutral Q9P1V8 K454E Neutral Neutral Q9P1V8 L18P Neutral Neutral Q9P1V8 K370E Neutral Neutral P98073 E641K Neutral Disease P98073 S732P Neutral Disease P98073 T65I Neutral Neutral P98073 Y828C Neutral Disease P98073 Q134E Neutral Neutral P98073 N660H Neutral Neutral P98073 S545C Neutral Neutral P98073 K77R Neutral Neutral Q8TC05 T103I Neutral Neutral Q8TC05 R489H Neutral Neutral Q8TC05 P552L Neutral Neutral Q8TC05 V383I Neutral Neutral Q96LZ7 G259D Neutral Disease Q9NWR8 Y253F Neutral Neutral Q9NWR8 I255V Neutral Neutral Q12981 Q14H Neutral Disease Q14164 E128K Neutral Disease Q14164 I543M Neutral Neutral Q14164 E515D Neutral Neutral Q14164 A602V Neutral Neutral Q14164 A371T Neutral Neutral Q14164 G660E Neutral Neutral Q14164 T483M Neutral Neutral Q14164 P713L Neutral Neutral Q03431 R150C Disease Disease Q03431 H223R Disease Disease Q03431 I458R Disease Disease Q03431 P132L Disease Disease Q03431 T410P Disease Disease Q03431 T410R Disease Disease Q8N5Y8 S280P Neutral Neutral Q13107 Y620C Neutral Disease Q14246 A298V Neutral Disease Q14246 S140R Neutral Neutral P48960 R367Q Neutral Neutral Q9UHX3 L614F Neutral Neutral Q9UHX3 T605I Neutral Disease Q14246 A57T Neutral Neutral Q14246 V424I Neutral Neutral Q14246 V589I Neutral Neutral Q14246 N254S Neutral Neutral Q14246 V724L Neutral Neutral Q9UHX3 S665F Neutral Disease Q14246 V539I Neutral Neutral Q14246 Q496K Neutral Neutral Q14246 D174N Neutral Neutral Q14246 T389M Neutral Neutral Q14246 F691C Neutral Disease Q86YB8 D129V Neutral Neutral Q86YB8 H465Q Neutral Neutral Q9BUT1 N70S Neutral Neutral Q7Z591 Q1097R Neutral Neutral Q7Z591 R1119Q Neutral Neutral Q7Z591 S1303P Neutral Neutral Q7Z591 Y1327C Neutral Neutral Q7Z591 P624L Neutral Neutral O00206 C246S Neutral Neutral O00206 R763H Neutral Disease O00206 F342Y Neutral Neutral O00206 Q834H Neutral Neutral O00206 D299G Neutral Disease O00206 Q188R Neutral Neutral O00206 T175A Neutral Neutral O00206 S400N Neutral Neutral O00206 E474K Neutral Neutral O00206 Q510H Neutral Neutral O00206 L385F Neutral Neutral O00206 N329S Neutral Neutral O00206 T399I Neutral Neutral O00206 K694R Neutral Neutral O00206 F443L Neutral Disease P07992 F231L Disease Neutral P07992 A266T Neutral Disease O95561 S137N Neutral Neutral O95561 M97V Neutral Neutral P40692 L607H Disease Neutral P40692 K618T Disease Neutral P40692 L559R Disease Disease P40692 N551T Disease Neutral P40692 H718Y Neutral Disease P40692 A441T Disease Neutral P40692 R226L Disease Disease P40692 S295T Disease Neutral P40692 E578G Disease Disease P40692 L582V Disease Neutral P40692 V326A Disease Disease P40692 S93G Disease Neutral P40692 V716M Disease Neutral P40692 R325Q Neutral Neutral P40692 I68N Disease Disease P40692 Y379C Disease Disease P40692 V506A Disease Neutral P40692 A128P Disease Disease P40692 A111V Disease Disease P40692 T117R Disease Disease P40692 I107R Disease Disease P40692 A586P Disease Disease P40692 N64S Disease Disease P40692 R217G Neutral Disease P40692 A492T Disease Neutral P40692 M35R Disease Disease P40692 K618A Disease Disease P40692 R182K Disease Neutral P40692 Q542L Disease Disease P40692 V384D Neutral Disease P40692 S406N Neutral Neutral P40692 S193P Disease Disease P40692 L729V Neutral Neutral P40692 P603R Disease Neutral P40692 K751R Disease Neutral P40692 R265H Neutral Disease P40692 S44F Disease Disease P40692 P28L Disease Disease P40692 T662P Disease Neutral P40692 V213M Disease Neutral P40692 R69K Disease Neutral P40692 G22A Neutral Disease P40692 G67R Disease Disease P40692 L549P Disease Disease P40692 L588P Disease Disease P40692 G101D Disease Disease P40692 R659P Disease Disease P40692 Q689R Neutral Neutral P40692 R659L Disease Disease P40692 V185G Disease Disease P40692 H329P Disease Disease P40692 P648S Disease Disease P40692 I565F Disease Neutral P40692 K84E Disease Disease P40692 R217C Disease Disease P40692 R687W Disease Neutral P40692 T117M Disease Disease P40692 Q62K Disease Disease P40692 P309S Neutral Disease P40692 G244V Neutral Disease P40692 I32V Neutral Neutral P40692 L574P Disease Disease P40692 F80V Disease Disease P40692 R182G Disease Disease P40692 G244D Disease Disease P40692 G67W Disease Disease P40692 A681T Disease Disease P40692 L622H Disease Disease P40692 C77R Disease Disease P40692 I219V Neutral Neutral P40692 R18C Disease Disease Q5BIV9 T7M Neutral Neutral Q5SVZ6 V73M Neutral Neutral Q6PCD5 I564V Neutral Neutral Q6PCD5 I770T Neutral Neutral Q6PCD5 R392K Neutral Neutral Q6PCD5 T90N Neutral Neutral Q8NHR7 P31R Neutral Neutral Q06187 R520Q Disease Disease Q06187 Y40C Disease Disease Q06187 V626G Disease Neutral Q06187 H362Q Disease Disease Q06187 V319A Disease Disease Q06187 K430E Disease Disease Q06187 R28P Disease Disease Q06187 H364P Disease Disease Q06187 R28C Disease Disease Q06187 D521H Disease Disease Q06187 F644S Disease Disease Q06187 R544K Disease Disease Q06187 G302E Disease Disease Q06187 V535F Disease Disease Q06187 A582V Disease Disease Q06187 G594E Disease Disease Q06187 T33P Disease Disease Q06187 R525G Disease Disease Q06187 A508D Disease Disease Q06187 R562P Disease Disease Q06187 G594R Disease Disease Q06187 K430R Disease Disease Q06187 W563L Disease Disease Q06187 T117P Disease Neutral Q06187 R28H Disease Disease Q06187 Q127H Disease Neutral Q06187 L512P Disease Disease Q06187 N526K Disease Disease Q06187 Y39S Disease Disease Q06187 P619T Disease Disease Q06187 M477R Disease Disease Q06187 R307G Disease Disease Q06187 E445D Disease Disease Q06187 D521N Disease Disease Q06187 P619A Disease Disease Q06187 C506Y Disease Disease Q06187 R562W Disease Disease Q06187 M509I Disease Disease Q06187 G462D Disease Disease Q06187 V64D Disease Disease Q06187 S592P Disease Disease Q06187 S115F Disease Disease Q06187 R307T Disease Disease Q06187 E589K Disease Disease Q06187 M630K Disease Disease Q06187 C502F Disease Disease Q06187 K19E Disease Neutral Q06187 R288W Disease Disease Q06187 R641C Disease Disease Q06187 E589D Disease Disease Q06187 L518R Disease Disease Q06187 S366F Disease Disease Q06187 L295P Disease Disease Q06187 R372G Disease Disease Q06187 R544G Disease Disease Q06187 G613D Disease Disease Q06187 L11P Disease Disease Q06187 L647P Disease Disease Q06187 Y40N Disease Disease Q06187 V113D Disease Disease Q06187 L408P Disease Disease Q06187 M587L Disease Neutral Q06187 Y598C Disease Disease Q06187 Y334S Disease Disease Q06187 N365Y Disease Disease Q06187 Y476D Disease Disease Q06187 L652P Disease Disease Q06187 A607D Disease Disease Q06187 K12R Disease Disease Q06187 C506R Disease Disease Q06187 Y361C Disease Disease Q06187 A523E Disease Disease Q06187 R525Q Disease Disease Q06187 L358F Disease Disease Q06187 C155R Disease Disease Q06187 M630T Disease Disease Q06187 S14F Disease Disease Q06187 R641H Disease Disease Q06187 I429N Disease Disease Q06187 R525P Disease Disease Q06187 G414R Disease Disease Q06187 C633Y Disease Disease Q06187 C502W Disease Disease Q06187 F559S Disease Neutral Q06187 E567K Disease Neutral Q06187 I370M Disease Disease Q06187 D308E Disease Neutral Q06187 D521G Disease Disease Q06187 L369F Disease Disease Q06187 C154S Disease Disease Q06187 R288Q Disease Disease Q06187 I61N Disease Disease Q06187 M509V Disease Disease Q06187 A622P Disease Disease Q06187 P619S Disease Disease Q06187 W581R Disease Disease Q06187 F583S Disease Neutral Q06187 S578Y Disease Disease Q06187 V64F Disease Disease Q06187 T184P Disease Neutral Q06187 Y418H Disease Disease Q06187 K27R Disease Neutral Q06187 G462V Disease Disease Q06187 L542P Disease Disease Q06187 L512Q Disease Disease Q06187 C155G Disease Disease Q06187 G302R Disease Disease Q06187 F644L Disease Disease Q06187 F25S Disease Neutral Q06187 E589G Disease Disease Q9Y2R2 R620W Neutral Neutral P25105 A224D Neutral Neutral P25105 N338S Neutral Neutral Q9NNZ6 Q100R Neutral Neutral Q8WWZ8 S237P Neutral Disease P51168 P616S Disease Neutral P51168 P618R Disease Neutral P51168 Y620H Disease Disease P51168 G37S Disease Disease P51168 P617S Disease Neutral P51168 P616L Disease Disease Q7L5A8 P97A Neutral Neutral P19174 S739T Neutral Neutral P16885 R268W Neutral Neutral P16885 H244R Neutral Neutral P19174 T209N Neutral Neutral P19174 I813T Neutral Neutral P19174 S279G Neutral Neutral Q9GZV4 E42D Neutral Neutral Q96MN9 A72V Neutral Neutral Q96MN9 P249S Neutral Neutral Q96MN9 P106L Neutral Neutral Q15648 S1240G Neutral Neutral Q9BV36 T289I Neutral Neutral Q9BV36 H347R Neutral Neutral Q9BV36 G172D Neutral Neutral Q9BV36 R139W Neutral Disease Q9BV36 L153P Neutral Neutral Q9BV36 D163N Neutral Neutral Q9BV36 R35W Disease Disease Q9BV36 V374A Neutral Neutral Q9C009 Q61P Neutral Neutral Q9C009 T60P Neutral Neutral Q8N283 N978D Neutral Neutral Q8N283 P428S Neutral Neutral Q8IY26 S140W Neutral Neutral O00584 R236W Neutral Neutral Q9BXJ7 T41I Disease Neutral P17181 T359M Neutral Neutral P17181 V307I Neutral Neutral P17181 V168L Neutral Neutral Q6P2M8 Q262H Neutral Neutral O95201 A255D Neutral Neutral O95201 T43A Neutral Neutral Q9H7B2 A41G Neutral Neutral Q9H7B2 G60S Neutral Neutral Q1MX18 Q450R Neutral Neutral P50747 L237P Disease Disease P50747 G581S Disease Disease P50747 G582R Disease Disease P50747 T462I Disease Disease P50747 R508W Disease Disease P50747 V550M Disease Neutral P50747 V333E Disease Neutral P50747 N511K Disease Disease P50747 L216R Disease Disease P50747 D571N Disease Disease Q96D46 E6K Neutral Neutral P08174 R52L Neutral Neutral P00491 E89K Disease Disease P00491 A174P Disease Disease P00491 G51S Neutral Neutral P00491 R234P Disease Disease P00491 Y192C Disease Disease P00491 D128G Disease Disease Q96RI0 P310L Neutral Disease Q96RI0 R215Q Neutral Disease Q96RI0 F296V Neutral Disease Q96RI0 A120T Neutral Neutral P11686 N138T Neutral Neutral P11686 A116D Disease Disease P11686 N186S Neutral Neutral P11686 E66K Disease Neutral P11686 L188Q Disease Disease P11686 R167Q Disease Neutral P11686 I73T Disease Neutral P28070 I234T Neutral Disease P28070 M95I Neutral Neutral Q8N4T4 H306R Neutral Neutral P35475 P496L Disease Disease P35475 H82P Disease Disease P35475 G409R Disease Neutral P35475 F602I Disease Neutral P35475 R619G Disease Neutral P35475 S423R Disease Neutral P35475 R383H Disease Neutral P35475 V454I Neutral Neutral P35475 R89W Disease Disease P35475 L490P Disease Neutral P35475 R628P Disease Disease P35475 T366P Disease Neutral P35475 A327P Disease Disease P35475 L238Q Disease Disease P35475 D349Y Disease Disease P35475 E182K Disease Disease P35475 S260F Disease Neutral P35475 G51D Disease Disease P35475 G208D Disease Disease P35475 W626R Disease Disease P35475 P533R Disease Disease P35475 R89Q Disease Disease P35475 L346R Disease Disease P35475 V279A Neutral Neutral P35475 L218P Disease Neutral P35475 R105Q Neutral Neutral P35475 R363C Disease Disease P35475 A361T Neutral Neutral P35475 N350I Disease Disease P35475 D349N Disease Disease P35475 A79V Disease Neutral P35475 A75T Disease Disease P35475 R489P Disease Neutral P35475 Q380R Disease Neutral P35475 M504T Disease Neutral P35475 M133I Disease Neutral P35475 G116R Neutral Neutral P35475 R492P Disease Disease P35475 T388R Disease Neutral P35475 H33Q Neutral Neutral Q9UBP4 G335R Neutral Neutral Q7RTU1 T40S Neutral Neutral Q7RTU1 R25Q Neutral Neutral Q9BZQ2 V563M Neutral Neutral O95243 S342P Neutral Neutral O95243 D568H Neutral Neutral O95243 A273T Neutral Neutral O95243 I358T Neutral Neutral O95243 E346K Neutral Neutral O95243 C61R Neutral Neutral O95243 A273S Neutral Neutral Q9BZJ4 L247F Neutral Neutral Q8TBP6 K186Q Neutral Neutral Q8TBP6 T123I Neutral Neutral O75771 R232Q Neutral Neutral O75771 A225T Neutral Neutral O75771 E233G Neutral Neutral O75771 R165Q Neutral Neutral O75771 R24S Neutral Neutral O43653 E39K Neutral Neutral Q2TAZ0 G948R Neutral Neutral Q2TAZ0 A627V Neutral Neutral Q2TAZ0 V175I Neutral Neutral Q5XX13 I23N Neutral Disease Q5XX13 A821T Neutral Neutral Q9UPQ0 T759M Neutral Neutral Q96IZ2 V202I Neutral Neutral P04440 M105I Neutral Neutral P01913 F193V Neutral Neutral P01913 Y66N Neutral Disease Q30154 L28S Neutral Neutral P04229 Q99E Neutral Neutral Q30134 G115V Neutral Neutral P01913 L96I Neutral Neutral P01913 G115V Neutral Neutral P13761 T106N Neutral Disease P01911 Y59H Neutral Neutral P04440 K98R Neutral Neutral P04229 G164D Neutral Disease P13760 L96I Neutral Neutral P04440 L37V Neutral Neutral P04440 L207M Neutral Disease P04229 V114A Neutral Neutral P04229 Y76F Neutral Disease P04229 A169T Neutral Disease P79483 R40C Neutral Disease Q30134 F96I Neutral Neutral P13760 G115V Neutral Neutral P04440 G114E Neutral Neutral P04229 R100E Neutral Neutral P04229 Q178H Neutral Disease P79483 V114A Neutral Disease P13765 L234F Neutral Disease P04229 R33Q Neutral Disease P04440 P115A Neutral Neutral P04440 A85E Neutral Disease P13760 K100R Neutral Neutral P04229 Y107H Neutral Disease P04229 Q39E Neutral Disease P04229 Q99D Neutral Disease P04440 F38Y Neutral Neutral P13761 R58S Neutral Disease P04229 R100A Neutral Neutral P01913 H59S Neutral Neutral P04229 L96I Neutral Neutral P13765 R18Q Neutral Neutral P79483 V236M Neutral Disease P04229 V236M Neutral Disease P04229 Q99H Neutral Disease P04440 E62Q Neutral Disease P04440 M105V Neutral Neutral P04229 V171M Neutral Disease P04229 G115V Neutral Neutral P04229 T13A Neutral Neutral P04229 A103E Neutral Neutral P04440 I244T Neutral Disease P13760 K100E Neutral Disease P13760 D86S Neutral Disease P04229 T210I Neutral Neutral P13760 A103E Neutral Neutral P04440 A65V Neutral Neutral Q30134 S86D Neutral Neutral P01911 I96F Neutral Disease P04229 Y89S Neutral Disease P01913 D86V Neutral Disease P79483 G102A Neutral Neutral P13760 Q99D Neutral Disease P01913 Y89S Neutral Disease P04440 M116V Neutral Neutral P01913 R80T Neutral Neutral P04440 G40V Neutral Disease P20039 R100E Neutral Neutral P04229 R33K Neutral Disease Q30154 G154A Neutral Disease P04440 E86D Neutral Disease P04229 T106N Neutral Disease P04229 A29S Neutral Disease P01911 V115G Neutral Neutral P01918 D167G Neutral Neutral P01913 D86S Neutral Disease P01913 H59Y Neutral Neutral P04229 S66Y Neutral Neutral P04229 R195Q Neutral Neutral P04440 K98E Neutral Disease P04440 F64Y Neutral Neutral P04229 Q253E Neutral Disease P04229 A102G Neutral Disease P13761 V107Y Neutral Neutral P04229 G74R Neutral Disease P13765 V244I Neutral Neutral P20039 G115V Neutral Neutral P59020 G23V Neutral Neutral P59020 R76L Neutral Neutral P07602 C388F Disease Disease P07602 C241S Disease Disease P07602 N215H Disease Disease P07602 T217I Disease Disease P07602 L349P Disease Disease P07602 N215K Disease Disease Q5VZ19 V101I Neutral Neutral Q5VZ19 R67Q Neutral Neutral P31151 E28D Neutral Neutral Q9Y2D1 L121P Neutral Neutral Q8IVT5 S225P Neutral Neutral O94822 S403L Neutral Neutral Q5DX21 T39P Neutral Neutral Q5DX21 E333D Neutral Neutral Q96G97 N88S Disease Neutral Q96G97 S90L Disease Disease Q96G97 A212P Disease Disease Q86VE3 W92R Neutral Neutral Q12894 R438Q Neutral Neutral Q9BRP8 E66Q Neutral Neutral Q8IVI9 E473G Neutral Neutral Q9ULV8 H405Y Neutral Neutral P36897 R487W Disease Disease P37023 G211D Disease Disease P37023 W399S Disease Disease P37023 R411W Disease Disease P36894 C82Y Disease Disease P37023 A347P Disease Disease P37023 G223R Disease Disease P37023 L337P Disease Disease P37023 A482V Disease Disease P36894 R443C Disease Disease P36897 K232E Disease Disease Q04771 R206H Disease Disease P37023 S333I Disease Neutral P37023 R479L Disease Disease P37023 R374W Disease Disease P36894 A338D Disease Disease P37023 W50C Disease Neutral P36894 C130R Disease Disease P37023 C77W Disease Disease P36897 S241L Disease Neutral P37023 L285F Disease Neutral P37023 E407D Disease Disease P37023 C51Y Disease Disease P36897 R487P Disease Disease O00238 R486W Disease Neutral P36897 Y291C Neutral Disease P36897 M318R Disease Disease P36894 C124R Disease Disease P37023 F425L Disease Neutral P36896 F146L Neutral Disease P37023 R484W Disease Neutral P36894 P2T Neutral Neutral P37023 A306P Disease Neutral P37023 R67Q Disease Neutral P37023 E215K Disease Disease P37023 K487T Disease Neutral P37023 C344Y Disease Disease P37023 I398N Disease Disease P37023 E379K Disease Disease P36894 V450M Neutral Disease P37023 R411Q Disease Disease P37023 G48R Disease Neutral P36897 D400G Disease Disease P36896 L408V Neutral Neutral P36897 T200I Disease Disease P37023 R67W Disease Disease P37023 K229R Disease Disease P37023 F425V Disease Neutral O00238 I200K Disease Disease P37023 I245N Neutral Neutral P37023 P424T Disease Disease P37023 R374Q Disease Disease P37023 P378L Disease Disease P37023 M376V Disease Disease P36894 C376Y Disease Disease O00238 R486Q Disease Neutral P37023 R411P Disease Disease P36897 V153I Neutral Neutral P37023 H314Y Disease Disease P36897 R487Q Disease Neutral P36894 M470T Disease Neutral P36894 Y62D Disease Disease P37023 M376R Disease Disease P37023 D397G Disease Disease P37023 D179A Disease Disease P37023 N96D Disease Disease Q8IWE5 I32T Neutral Neutral Q6XYB7 S158F Neutral Neutral Q9Y2F5 K596E Neutral Neutral Q9Y2F5 S391C Neutral Neutral Q9Y2F5 G1058D Neutral Neutral Q9Y2F5 Q1597P Neutral Neutral Q9Y2F5 T1054A Neutral Neutral Q9Y2F5 I901V Neutral Neutral A0AVI4 L83I Neutral Neutral P13521 Y61H Neutral Disease P13521 D535G Neutral Neutral P13521 R421G Neutral Neutral P13521 P564L Neutral Neutral P13521 D294G Neutral Neutral Q02083 V151I Neutral Neutral O60934 Q216K Neutral Neutral O60934 V210F Neutral Neutral O60934 L574I Neutral Neutral O60934 P266L Neutral Neutral O60934 K105N Neutral Disease O60934 T497A Neutral Neutral O60934 R215W Neutral Neutral O60934 S93L Disease Neutral O60934 D95N Disease Neutral O60934 E185Q Neutral Neutral O60934 L150F Disease Neutral O60934 I171V Disease Neutral P59894 E7G Neutral Neutral P59894 V83M Neutral Neutral A2A3K4 L571Q Neutral Neutral Q9H7U1 S819P Neutral Neutral Q9H7U1 N84S Neutral Neutral Q9H7U1 C755Y Neutral Neutral Q9H7U1 P821S Neutral Neutral Q9HCJ1 M48T Disease Disease Q9HCJ1 P5T Disease Disease Q9HCJ1 W292R Disease Disease Q9HCJ1 P5L Disease Disease Q9HCJ1 G389R Disease Neutral Q9HCJ1 C331R Disease Disease Q8WXF7 R217Q Disease Disease Q8WXF7 A161P Disease Disease Q8WXF7 H247P Disease Disease Q8WXF7 H258R Disease Neutral Q8WXF7 R239C Disease Disease Q8WXF7 S259Y Disease Disease P51956 P60R Neutral Disease P51956 E477K Neutral Neutral P51956 R259G Neutral Disease P51956 R122H Neutral Neutral P51956 D461N Neutral Neutral P51956 P170L Neutral Disease P51956 H23L Neutral Neutral P51956 E305D Neutral Neutral Q9H668 T151A Neutral Neutral Q9H668 S248C Neutral Neutral Q15165 A148G Neutral Neutral Q15166 E146K Neutral Neutral P27169 Q192R Neutral Neutral Q15166 A179D Neutral Disease P27169 M55L Neutral Neutral P27169 I102V Neutral Neutral Q15165 V172L Neutral Disease Q15165 C311S Neutral Neutral P49675 A203D Neutral Disease P49675 R182L Disease Disease P49675 R121W Neutral Disease P49675 A218V Disease Neutral P49675 L275P Disease Neutral P49675 E169G Disease Disease P49675 E169K Disease Disease P49675 R217T Disease Disease P49675 M225T Disease Neutral Q5FVE4 A143V Neutral Disease Q5FVE4 R650S Neutral Disease Q5FVE4 G586D Neutral Neutral Q5FVE4 K152R Neutral Disease Q5FVE4 E626Q Neutral Disease Q5FVE4 G584D Neutral Neutral Q5FVE4 R624K Neutral Neutral Q5FVE4 P601R Neutral Disease Q10981 I140F Neutral Disease Q10981 I25V Neutral Neutral Q10981 G258S Neutral Disease Q10981 D172N Neutral Neutral Q10981 R138C Neutral Disease Q14181 S588N Neutral Neutral Q14181 G583R Neutral Neutral Q8IWA6 I46V Neutral Neutral Q8IWA6 V393I Neutral Neutral Q8IWA6 T115A Neutral Neutral Q16581 V136A Neutral Neutral Q8WXD2 S125N Neutral Neutral Q8WXD2 M233V Neutral Neutral P08235 S815R Disease Neutral P08235 L979P Disease Disease P08235 P759S Disease Disease P08235 G633R Disease Disease P08235 N770K Disease Disease P08235 S818L Disease Disease P08235 Q776R Disease Disease P08235 C645S Disease Disease P08235 E972G Disease Disease P08235 S805P Disease Disease P08235 L769P Disease Disease P08235 R659S Disease Disease P08235 L924P Disease Disease Q7RTR2 V567M Neutral Disease Q5T1B0 A742V Neutral Neutral Q5T1B0 E991Q Neutral Neutral O43529 V20L Neutral Disease O43529 D258N Neutral Disease Q7L3S4 D207N Neutral Disease P12270 S960N Neutral Neutral Q9HC38 M282I Neutral Neutral P36575 L44F Neutral Neutral P10523 R384C Neutral Disease P10523 P364L Neutral Disease P10523 I76V Neutral Neutral P10523 T125M Neutral Neutral P10523 V378I Neutral Neutral P10523 R84C Neutral Disease P10523 V403I Neutral Neutral Q9H9V9 D65E Neutral Neutral Q9H9V9 A461V Neutral Neutral Q9H9V9 A11V Neutral Neutral Q9H9V9 G16C Neutral Neutral Q9NZ56 R1468H Neutral Neutral O14986 A415T Neutral Neutral P07101 R337H Neutral Disease P07101 T494M Neutral Disease P07101 V112M Neutral Neutral P07101 T276P Neutral Disease P07101 V499M Neutral Disease O14678 A304T Neutral Neutral O14678 E368K Neutral Neutral P11801 N301S Neutral Neutral Q8TAI1 G62R Neutral Neutral Q9H3H5 Y170C Disease Disease Q9UBW5 N529D Neutral Neutral Q9UBW5 S48N Neutral Neutral Q96BY7 T398I Neutral Neutral Q96BY7 Q214E Neutral Neutral Q9UJQ4 H888R Disease Disease Q9UJQ4 L507R Neutral Neutral Q9UJQ4 I798L Neutral Neutral Q2TBE0 Y890C Neutral Neutral Q2TBE0 H439Y Neutral Neutral Q2TBE0 G533R Neutral Neutral Q2TBE0 P206T Neutral Neutral Q2TBE0 H441Q Neutral Neutral P09601 P106L Neutral Neutral P09601 D7H Neutral Neutral Q7Z6M1 D313G Neutral Neutral Q7Z6M1 H73Y Neutral Neutral Q7Z6M1 R60G Neutral Disease Q7Z6M1 M333I Neutral Neutral Q7Z6M1 T67P Neutral Disease P29803 R376G Neutral Disease P08559 R72C Disease Disease P08559 R10P Disease Disease P08559 G162R Disease Disease P08559 R263Q Disease Disease P08559 R288H Disease Disease P08559 H292L Disease Disease P08559 P217L Disease Disease P08559 Y243N Disease Neutral P08559 R302H Disease Disease P08559 M282L Neutral Neutral P29803 M280L Neutral Neutral P08559 F205L Disease Neutral P08559 D315N Disease Disease P08559 H113D Disease Disease P08559 R302C Disease Disease P08559 V167M Disease Disease P08559 M210V Disease Disease P08559 T231A Disease Disease P08559 D258A Disease Disease P08559 A199T Disease Disease P08559 R378H Disease Disease P08559 R263G Disease Disease Q9H8J5 V55I Neutral Neutral Q9H8J5 N375Y Neutral Neutral Q5T0L3 V69A Neutral Neutral Q5T0L3 R217H Neutral Neutral Q96JP5 V37I Neutral Neutral Q96JP5 S207G Neutral Neutral P32004 R751P Disease Disease P32004 S674C Disease Neutral P32004 G452R Disease Disease P32004 V752M Disease Neutral P32004 A415P Disease Disease P32004 E309K Disease Neutral P32004 I219T Disease Disease P32004 I179S Disease Disease P32004 Y194C Disease Neutral P32004 R473C Disease Disease P32004 R739W Neutral Disease P32004 D202Y Disease Neutral P32004 R386C Disease Disease P32004 A691T Disease Disease P32004 A691D Disease Disease P32004 Y784C Disease Disease P32004 H30N Neutral Neutral P32004 S542P Disease Neutral P32004 R184Q Disease Disease P32004 K655E Disease Neutral P32004 W335C Disease Disease P32004 R632P Disease Disease P32004 A426D Disease Neutral P32004 G370R Disease Disease P32004 L482P Disease Neutral P32004 G268D Disease Disease P32004 G698R Disease Disease P32004 R184W Disease Neutral P32004 G121S Disease Disease P32004 C264Y Disease Disease P32004 G1239E Neutral Neutral P32004 S1224L Disease Disease P32004 V768F Disease Disease P32004 P240L Disease Disease P32004 S1194L Disease Disease P32004 W335R Disease Neutral P32004 D598N Disease Disease P32004 V421D Disease Neutral P32004 N408I Disease Disease P32004 P941L Disease Disease P32004 C497Y Disease Disease P32004 H210Q Disease Neutral P32004 V768I Neutral Neutral P32004 M741T Disease Neutral P32004 W9S Disease Disease P32004 L935P Disease Disease P32004 Y1070C Disease Neutral P32004 D770N Disease Neutral P00738 E194K Neutral Disease P00738 N193D Neutral Disease P00738 D397H Neutral Neutral P08493 K53E Neutral Neutral P08493 T102A Neutral Neutral P11277 R1403Q Neutral Neutral P11277 D1151N Neutral Neutral P11277 A2018G Disease Neutral P11277 N439S Neutral Neutral P11277 W2024R Disease Disease P11277 L2025R Disease Disease P11277 S2019P Disease Disease P11277 H1374R Neutral Neutral P11277 A2053P Disease Disease P11277 G1408R Neutral Disease P11277 S613I Neutral Neutral P11277 A2023V Disease Disease P34995 T223M Neutral Neutral P34995 A71T Neutral Neutral P34995 H256R Neutral Neutral Q5TAX3 D796Y Neutral Neutral Q8TDX9 V312F Neutral Disease Q8TDX9 K1272E Neutral Neutral Q8TDX9 E2410K Neutral Neutral Q8TDX9 R1053P Neutral Neutral P35250 A232V Neutral Disease Q8IYE1 S547T Neutral Neutral Q66K74 S411C Neutral Disease Q66K74 P538Q Neutral Neutral Q2TAK8 G551A Neutral Neutral Q2TAK8 R219G Neutral Neutral Q8N1W1 H780N Neutral Neutral Q8N1W1 H1640Q Neutral Neutral Q8N1W1 W225R Neutral Neutral Q8N1W1 S544L Neutral Neutral Q8N1W1 R585K Neutral Neutral Q8N1W1 P1548S Neutral Neutral Q8N1W1 P284Q Neutral Neutral Q8N1W1 R98M Neutral Neutral P25205 I590L Neutral Disease P25205 S105G Neutral Neutral P25205 R774W Neutral Neutral P25205 F287L Neutral Neutral P25205 E777K Neutral Neutral P25205 D280V Neutral Disease Q16769 Q71R Neutral Neutral Q9NXS2 P214L Neutral Neutral Q9H936 P206L Disease Neutral P40763 M143I Neutral Neutral P40763 V637L Disease Neutral P40763 T389I Disease Neutral P40763 R382L Disease Disease P40763 R423Q Disease Disease P40763 V637M Disease Disease P40763 F384S Disease Disease P40763 Y657C Disease Disease P40763 F561Y Neutral Disease P40763 F621V Disease Disease P40763 R382Q Disease Disease P40763 H437Y Disease Disease P40763 T622I Disease Disease P40763 Q32K Neutral Disease P42224 L706S Disease Disease P40763 S611N Disease Disease P40763 F384L Disease Disease P42224 L600P Disease Disease P51692 A630P Disease Disease P40763 R382W Disease Disease Q03426 I268T Disease Disease Q03426 G309S Disease Disease Q03426 L39P Disease Disease Q03426 T356M Neutral Neutral Q03426 N301T Disease Disease Q03426 A148T Disease Neutral Q03426 L265R Disease Disease Q03426 L265P Disease Disease Q03426 G202R Disease Disease Q03426 G326R Disease Disease Q03426 S150L Disease Disease Q03426 V377I Disease Neutral Q03426 V132I Disease Neutral Q03426 S52N Neutral Neutral Q03426 V310M Disease Disease Q03426 G376V Disease Disease Q03426 L264F Disease Neutral Q03426 R215Q Disease Neutral Q03426 P167L Disease Disease Q03426 H20Q Disease Disease Q03426 S135L Disease Disease Q03426 A334T Disease Disease Q03426 H20N Disease Disease Q03426 G211E Disease Disease Q03426 V250I Disease Disease Q03426 T243I Disease Disease Q03426 H20P Disease Disease Q03426 G335S Neutral Disease Q03426 G171R Disease Neutral O43526 N780T Neutral Neutral O43526 A306T Disease Disease O43526 K554N Disease Disease O43526 S247W Disease Disease O43526 M208V Disease Neutral O43526 H228Q Disease Neutral O43526 R214W Disease Disease O43526 R207W Disease Disease O43526 Y284C Disease Disease O43526 R333Q Disease Disease O43526 L243F Disease Disease Q6NXR0 D135N Neutral Disease Q9P1Y6 A1374V Neutral Neutral Q9P1Y6 E1231A Neutral Neutral Q9P1Y6 A1449V Neutral Neutral Q8N441 P362Q Neutral Neutral Q8N441 P464L Neutral Neutral Q6EEV6 M55V Neutral Disease Q9Y6A1 D433E Neutral Neutral Q9Y6A1 A200P Disease Disease Q9Y6A1 V428D Disease Disease Q9Y6A1 V327I Neutral Neutral Q9Y6A1 S537R Disease Disease Q9Y6A1 G76R Disease Disease Q9Y6A1 R251Q Neutral Neutral Q9Y6A1 R251W Neutral Neutral Q9UKY4 A54E Neutral Neutral P43489 R10C Neutral Neutral Q96EX1 L14V Neutral Neutral Q17R55 V216I Neutral Neutral Q17R55 P3S Neutral Neutral Q17R55 C160R Neutral Neutral Q92882 L159F Neutral Neutral P10619 Y395C Disease Disease P10619 Q49R Disease Disease P10619 Y249N Disease Neutral P10619 F440V Disease Disease P10619 S90L Disease Disease P10619 W65R Disease Disease Q8NCI6 V431M Neutral Neutral Q8NCI6 R121P Neutral Neutral Q8TBZ3 P159H Neutral Disease Q8IU81 M24I Neutral Neutral Q68CP4 M510K Disease Disease Q68CP4 D590V Disease Disease Q68CP4 G452S Disease Disease Q68CP4 E499K Disease Disease Q68CP4 R372C Disease Disease Q68CP4 P311L Disease Disease Q68CP4 S569L Disease Disease Q68CP4 P599L Disease Disease P49454 Y1018D Neutral Neutral P49454 T1105I Neutral Neutral P49454 M701V Neutral Neutral P49454 G1033R Neutral Neutral P49454 K1539R Neutral Neutral P49454 H494Q Neutral Neutral P49454 A1515T Neutral Neutral P49454 N3202K Neutral Neutral P49454 Q754E Neutral Neutral P49454 L1412S Neutral Neutral P49454 E2011A Neutral Neutral P49454 R815H Neutral Neutral P49454 R300C Neutral Neutral Q8N1S5 A111T Neutral Neutral Q13416 M106K Neutral Disease Q13416 R521Q Neutral Neutral O95379 S151C Neutral Disease Q8WVP5 A118V Neutral Neutral Q5T7N2 V246A Neutral Neutral Q5T7N2 R27S Neutral Neutral Q5T7N2 T613I Neutral Neutral Q5T7N2 P549T Neutral Neutral Q5T7N2 V309M Neutral Neutral Q5T7N2 K329N Neutral Neutral Q8N769 H26Y Neutral Neutral O95571 L185R Disease Disease O95571 T136A Disease Disease O95571 Y38C Disease Disease O95571 R163W Disease Disease Q8IUH4 R99K Neutral Disease P15918 L885R Disease Disease P15918 R561C Disease Disease P15918 E880K Neutral Disease P15918 R449K Neutral Disease P15918 E722K Disease Disease P15918 R975Q Disease Disease P15918 S169L Neutral Disease P15918 E669G Disease Disease P15918 D302E Neutral Disease P15918 R396L Disease Disease P15918 C328Y Disease Disease P15918 R244G Neutral Disease P15918 A156V Neutral Disease P15918 K820R Neutral Disease P15918 D429G Disease Disease P15918 R561H Disease Disease P15918 P525S Neutral Disease P15918 R624C Disease Disease P15918 R624H Disease Disease P15918 R559S Disease Disease P15918 Y912C Disease Disease P15918 R396H Disease Disease P15918 R247H Neutral Neutral P15918 R249H Neutral Neutral P15918 R737H Disease Disease P15918 S401P Disease Disease P15918 D887N Neutral Neutral P15918 R396C Disease Disease P15918 M435V Disease Neutral Q9UK55 Q384P Neutral Disease Q9UK55 T161S Neutral Neutral Q9UK55 G139R Neutral Disease Q9UK55 K46R Neutral Neutral Q9UK55 G271S Neutral Neutral Q9UK55 S61G Neutral Neutral P02818 R94Q Neutral Neutral O95498 V241I Neutral Neutral O95497 T336A Neutral Neutral O95498 D112E Neutral Neutral Q9NY84 T89A Neutral Disease O95498 T349S Neutral Neutral Q9NY84 H33R Neutral Disease O95497 D146N Neutral Neutral O95497 N131S Neutral Disease O95497 A63T Neutral Neutral O95498 T17N Neutral Neutral Q9NY84 E91K Neutral Disease O95497 T26I Neutral Neutral O95497 E296D Neutral Neutral O95497 V136L Neutral Disease O95497 I373T Neutral Neutral O95498 L404M Neutral Neutral O95498 V30A Neutral Disease O95497 A325E Neutral Neutral Q9NY84 V222A Neutral Neutral Q92698 V444E Disease Disease Q92698 P63H Disease Neutral Q92698 G325R Disease Disease Q92698 K151E Neutral Neutral P11117 S320F Neutral Neutral P11117 R29Q Neutral Neutral P33241 Q229K Neutral Neutral P33241 A100T Neutral Neutral Q9BYH1 M430I Neutral Neutral Q9BYH1 W185L Neutral Neutral Q5T0T0 P92S Neutral Disease Q5T0T0 Y266H Neutral Neutral P49279 D543N Neutral Neutral P49281 E399D Disease Disease P49279 A318V Neutral Neutral P49281 G212V Disease Disease P49279 Q30R Neutral Neutral P49281 R416C Disease Disease P06213 A1162E Disease Disease P06213 R1119W Disease Disease P06213 W1220L Disease Disease P06213 T937M Disease Disease P06213 G58R Disease Disease P06213 A1055V Disease Disease P06213 P1205L Disease Disease P06213 R926W Disease Disease P06213 R1158Q Disease Disease P06213 L120Q Disease Disease P06213 R1201Q Disease Disease P06213 N42K Disease Disease P06213 I925T Disease Disease P06213 F409V Disease Disease P06213 K487E Disease Neutral P06213 P220L Disease Disease P06213 N489S Disease Disease P06213 C301Y Disease Neutral P06213 L89P Disease Disease P06213 T858A Disease Neutral P06213 A1075D Disease Disease P06213 G386S Disease Disease P06213 R113P Disease Disease P06213 R279H Disease Disease P06213 W439S Disease Disease P06213 I1143T Disease Disease P06213 R1020Q Disease Disease P06213 M1180I Disease Disease P06213 G1035V Disease Disease P06213 S350L Disease Disease P06213 G393R Disease Disease P06213 L260P Disease Disease P06213 R762S Disease Disease P06213 V55A Disease Disease P06213 R1158W Disease Disease P06213 P997T Disease Disease P06213 R1201W Disease Disease P06213 A119V Disease Disease P06213 N458D Disease Disease P06213 A1161T Disease Disease P06213 R1191Q Disease Disease P06213 I146M Disease Disease P06213 W1227S Disease Disease P06213 D86G Disease Disease P06213 H236R Disease Disease P06213 E1206K Disease Disease P06213 R1378Q Disease Neutral P06213 E1206D Disease Disease P06213 C280Y Disease Disease P06213 R279C Disease Disease P06213 V167L Disease Neutral P05546 A7T Neutral Neutral P05546 K237R Neutral Neutral P05546 R208H Disease Disease P05546 T442M Neutral Disease P05546 H60P Neutral Neutral Q53R12 A27V Neutral Neutral O14730 S447L Neutral Neutral O14730 L336V Neutral Disease O14730 R441Q Neutral Disease Q9NR48 T1771A Neutral Neutral Q9NUJ1 I251V Neutral Neutral O00220 R209T Neutral Neutral O00220 T33I Neutral Neutral O00220 H141R Neutral Neutral O00220 E228A Neutral Neutral P25116 S166G Neutral Neutral O43156 A671V Neutral Neutral O43156 R1028K Neutral Neutral O43156 R450H Neutral Neutral O43156 A979T Neutral Neutral Q9BYV1 T212I Neutral Neutral Q9BYV1 V140I Neutral Neutral Q9BYV1 S102N Neutral Neutral Q9BYV1 V498L Neutral Neutral Q6P2P2 S483G Neutral Neutral Q6P2P2 C747Y Neutral Neutral Q5M775 M293L Neutral Neutral P78417 A236V Neutral Neutral P78417 S86C Neutral Disease Q9H4Y5 N142D Neutral Neutral P78417 A140D Neutral Disease P78417 E208K Neutral Neutral Q86VP6 A952V Neutral Disease Q5VVB8 N60I Neutral Disease Q5VVB8 E86G Neutral Neutral Q5VVB8 F80L Neutral Neutral Q5VVB8 F111V Neutral Neutral O75056 D303N Neutral Neutral O75056 T329I Neutral Neutral O75056 V208I Neutral Neutral Q6W0C5 E51Q Neutral Neutral Q6XZF7 C1413W Neutral Neutral P35325 P39S Neutral Neutral O43175 V425M Disease Neutral O43175 V490M Disease Neutral O95628 A7G Neutral Neutral Q8N3L3 A11T Neutral Neutral Q8N3L3 P650A Neutral Neutral Q2KHM9 V501M Neutral Neutral Q2KHM9 P566L Neutral Neutral Q2KHM9 E375D Neutral Neutral Q2KHM9 R896Q Neutral Neutral Q2KHM9 N444D Neutral Neutral Q2KHM9 P466L Neutral Neutral Q2KHM9 H201Q Neutral Neutral Q2KHM9 E375G Neutral Neutral Q96A59 R60K Neutral Neutral P55084 G59D Disease Disease P55084 L121P Disease Disease P55084 D263G Disease Disease P24752 G379V Disease Disease P55084 R61H Disease Disease P55084 R61C Disease Disease P24752 N93S Disease Disease P55084 D242G Disease Disease P24752 A333P Disease Disease P55084 T133P Disease Disease P24752 A5P Neutral Neutral P55084 G280D Disease Neutral P55084 R117G Disease Disease P24752 N158D Disease Disease P55084 R247H Disease Disease P24752 G183R Disease Disease P55084 P294L Disease Disease P24752 A301P Disease Disease Q9BWD1 K211R Neutral Disease P24752 I312T Disease Disease P55084 R444K Disease Disease P55084 P294R Disease Disease P09110 E172D Neutral Neutral P24752 A380T Disease Disease P24752 G152A Disease Disease P55084 G301S Disease Disease P24752 T297M Disease Disease Q6R2W3 M155V Neutral Neutral Q8N2G6 E43V Neutral Neutral Q9Y2Y1 S24A Neutral Neutral Q6P3S1 V216M Neutral Neutral Q9BVN2 S362F Neutral Neutral P52701 D1213V Neutral Disease P52701 Y538S Neutral Neutral P52701 S503C Neutral Neutral P52701 V1260I Neutral Neutral P52701 A25V Neutral Neutral P52701 K13T Neutral Neutral P52701 I886V Neutral Neutral P52701 V800L Neutral Neutral P52701 R468H Neutral Disease P52701 S65L Neutral Neutral P52701 E221D Neutral Neutral P52701 P623A Neutral Neutral P52701 S580L Neutral Neutral P52701 L396V Neutral Neutral P52701 E220D Neutral Neutral P52701 V1232L Neutral Neutral P52701 V878A Neutral Neutral P52701 G39E Neutral Neutral P52701 S144I Neutral Neutral P52701 M492V Neutral Neutral P52701 Q698E Neutral Neutral P52701 R1321G Neutral Disease P52701 E1234Q Neutral Neutral Q6NUT2 S51A Neutral Neutral Q6NUT2 A41V Neutral Neutral Q6NUT2 M37V Neutral Neutral Q6NUT3 Y182H Neutral Disease Q6NUT3 R476C Neutral Neutral Q6NUT3 R243H Neutral Neutral P33991 E460G Neutral Neutral P33991 L650M Neutral Neutral P03952 A178T Neutral Neutral P03951 C339F Neutral Disease P03952 T358A Neutral Neutral P03952 H208P Neutral Disease P03951 F301L Disease Disease P03952 R560Q Neutral Disease P03952 S269C Neutral Neutral P03952 F311V Neutral Neutral P03951 A430V Disease Disease P03951 Q244R Disease Neutral P03951 R326C Disease Disease P03951 P66L Neutral Neutral P03951 L320P Disease Neutral P03951 W399R Neutral Disease P03952 S381A Neutral Neutral P03951 T322I Disease Disease P03951 S594R Disease Disease P03951 E341K Disease Neutral P03952 H202Q Neutral Neutral P03951 T493I Disease Neutral P03951 W246C Disease Disease P03951 F460V Disease Neutral P03951 T404N Disease Neutral P03951 I308F Neutral Neutral P03952 N143S Neutral Neutral P03952 Q442P Neutral Disease P03951 S266N Disease Neutral P03951 D34H Disease Disease P03952 A210E Neutral Disease Q9BXF9 E410D Neutral Disease Q9BXF9 V296A Neutral Neutral Q9BXF9 G282A Neutral Neutral O00411 E555A Neutral Neutral P30968 S217R Disease Disease P30968 Y284C Disease Disease P30968 E90K Disease Neutral P30968 A171T Disease Disease P30968 N10K Disease Neutral P30968 R262Q Disease Neutral P30968 R139H Disease Disease P30968 Q106R Disease Neutral P30968 A129D Disease Disease P30968 S168R Disease Disease O14792 P22T Neutral Neutral Q86SJ6 I644L Neutral Neutral Q86SJ6 I535T Neutral Neutral Q6V702 I237V Neutral Neutral Q6V702 T155M Neutral Neutral Q86UQ0 T216R Neutral Neutral Q8NA56 L94P Neutral Disease Q8NA56 A276T Neutral Neutral Q8NA56 H140Y Neutral Neutral O15085 H1427R Neutral Neutral Q86SH4 T50S Neutral Neutral Q8IYU4 Q143K Neutral Neutral Q8IYU4 R171C Neutral Neutral Q8IYU4 G379W Neutral Neutral Q8IYU4 G259D Neutral Disease Q8IYU4 Q455E Neutral Neutral Q8IYU4 A275V Neutral Neutral Q8IYU4 D92V Neutral Disease Q8IYU4 H274Y Neutral Neutral Q96LI9 R187H Neutral Neutral Q96LI9 R24C Neutral Neutral Q99999 V29M Neutral Neutral P16410 T17A Neutral Neutral Q17RQ9 V118L Neutral Neutral Q07889 P655L Neutral Neutral Q07889 Y702H Disease Neutral Q07889 R552K Disease Neutral Q07889 W729L Disease Neutral Q07890 L672I Neutral Neutral Q07889 W432R Disease Disease Q07889 D309Y Disease Neutral Q07889 I733F Disease Neutral Q07889 H1320R Neutral Neutral Q07889 Q977R Neutral Neutral Q07889 E108K Disease Neutral Q07889 M269R Disease Disease Q07889 E433K Disease Disease Q07889 R552S Disease Neutral Q07889 C441Y Disease Disease Q07889 T266K Disease Neutral Q07889 L550P Disease Disease Q07889 Y337C Disease Neutral Q07889 G434R Disease Disease Q07889 S548R Disease Disease Q07889 E846K Disease Neutral Q07889 R552G Disease Neutral Q12887 T196K Disease Neutral Q12887 D336G Disease Disease Q12887 D336V Disease Disease Q12887 N204K Disease Disease Q12887 P225L Disease Disease Q5VTQ0 V354I Neutral Neutral Q3KP44 V344M Neutral Neutral P57058 R157W Neutral Disease P57058 R591C Neutral Neutral P57058 E625K Neutral Neutral P57058 M648T Neutral Neutral Q86VH2 R300Q Neutral Disease Q86VH2 I213V Neutral Neutral Q13370 A87V Neutral Neutral P17275 L230V Neutral Neutral P05412 T297M Neutral Neutral A1A4Y4 T94K Neutral Neutral A1A4Y4 E17D Neutral Neutral P06396 D214Y Disease Disease P06396 D214N Disease Disease P13385 V22A Neutral Neutral P13385 Y43D Neutral Neutral P07196 E396K Disease Disease P07196 N98S Disease Disease P07196 D468N Neutral Neutral P07196 P22S Disease Neutral P07196 Q332P Disease Disease P07196 P8Q Disease Neutral P07196 E90K Disease Disease P07196 P8L Disease Neutral P07196 P8R Disease Neutral P07196 L336P Disease Disease O94830 T186M Neutral Neutral Q53HL2 K12N Neutral Neutral P21817 M2423K Disease Disease P21817 R614C Disease Disease Q92736 N4104K Disease Disease Q92736 P4902L Disease Neutral P21817 S1489N Neutral Neutral Q92736 V4653F Disease Disease P21817 R471C Neutral Neutral P21817 G2434R Disease Disease P21817 T2206R Disease Disease P21817 R2163P Disease Disease P21817 G248R Disease Neutral P21817 R2454C Disease Disease P21817 G2060C Neutral Neutral P21817 R2163H Disease Neutral Q92736 S2246L Disease Disease P21817 R163C Disease Disease P21817 G341R Disease Disease Q92736 L433P Disease Disease P21817 R533H Disease Neutral P21817 R2458C Disease Disease Q92736 G1886S Neutral Neutral P21817 R2435H Disease Disease Q92736 R2474S Disease Disease P21817 R109W Disease Disease P21817 R2454H Disease Disease Q92736 V2306I Disease Neutral P21817 S1342G Neutral Neutral P21817 Y522S Disease Disease P21817 R1109K Neutral Neutral P21817 Q3756E Neutral Neutral Q92736 N2386I Disease Disease P21817 I403M Disease Neutral P21817 R614L Disease Disease P21817 T2206M Disease Disease P21817 R2458H Disease Disease Q92736 P2328S Disease Disease Q92736 Q2958R Neutral Neutral Q92736 R4497C Disease Disease Q92736 R4959Q Disease Neutral P21817 M485V Neutral Neutral P21817 R552W Disease Neutral P21817 R2163C Disease Disease Q92736 Q4201R Disease Disease P21817 P1787L Neutral Neutral P21817 R2435L Disease Disease P21817 V2168M Disease Neutral P21817 C35R Disease Disease Q7Z2Z2 I617V Neutral Neutral Q7Z2Z2 E478D Neutral Neutral Q7Z2Z2 K711R Neutral Neutral Q96EV8 P272S Neutral Neutral O75843 S377F Neutral Neutral O43747 P685H Neutral Neutral Q9H069 R191W Neutral Neutral Q9UN36 G48V Neutral Disease Q9Y512 I345V Neutral Neutral O94851 L1106P Neutral Neutral O94851 I220V Neutral Neutral O94851 R1089Q Neutral Neutral O60307 G883S Neutral Neutral O15393 K449N Neutral Neutral O15393 S254C Neutral Disease O15393 E329Q Neutral Neutral O15393 V160M Neutral Disease O15393 D491N Neutral Neutral P18084 L428V Neutral Neutral P05106 L288P Disease Disease P05106 C586R Disease Disease P05107 Q354H Neutral Neutral P05106 R240W Disease Disease P05107 N351S Disease Disease P05106 V453I Neutral Neutral P05106 Y141C Disease Disease P05106 I330N Disease Disease P05106 R240Q Disease Neutral P05107 R586W Disease Neutral P05107 G169R Disease Disease P05107 K196T Disease Neutral P05106 H306P Disease Disease P05107 G273R Disease Disease P05106 C532Y Disease Disease P05107 S138P Disease Disease P05107 D128N Disease Disease P05106 C400Y Disease Disease P05106 R242Q Disease Neutral P05106 L59P Neutral Neutral P05106 C568R Disease Disease P05106 R515Q Neutral Neutral P05106 S188L Disease Neutral P05106 R169Q Neutral Neutral P05106 M150V Disease Disease P05106 L143W Disease Disease P05107 P178L Disease Disease P05106 D145Y Disease Disease P05106 G598S Disease Neutral P05106 D243V Disease Disease P05106 R119W Disease Disease P05106 M321L Disease Neutral P05107 L149P Disease Disease P05106 D145N Disease Disease P05107 R593C Disease Disease P05106 S778P Disease Disease P05106 C601R Disease Disease P05107 G284S Disease Disease P05106 L222P Disease Disease P05106 G605S Disease Disease P05106 C586F Disease Disease O60687 T287S Neutral Neutral O60687 N327S Disease Neutral P78539 P225S Neutral Neutral P78539 S413F Neutral Neutral O60687 Y72S Disease Neutral Q8TEU8 V96M Neutral Neutral Q2M2I3 A91T Neutral Neutral Q2M2I3 R372H Neutral Neutral Q2M2I3 P311L Neutral Neutral Q8IUX1 A198V Neutral Neutral Q9HCI6 V81M Neutral Neutral Q9HCI6 F75L Neutral Neutral Q8WWK9 I323V Neutral Neutral P49815 R1743Q Disease Disease P49815 A607T Neutral Neutral P49815 L309Q Neutral Disease P49815 Y1549C Disease Disease P49815 R1240W Disease Neutral P49815 L361P Disease Disease P49815 E1783Q Disease Neutral P49815 L292P Disease Disease P49815 I490V Neutral Neutral P49815 V963M Disease Neutral P49815 H137R Disease Neutral P49815 R261P Disease Disease P49815 R1743P Disease Disease P49815 L1594M Disease Neutral P49815 F615S Neutral Disease P49815 N525S Disease Neutral P49815 A614D Disease Disease P49815 Y1650C Disease Disease P49815 M286T Neutral Neutral P49815 P1450R Neutral Neutral P49815 N1643K Disease Disease P49815 P816L Disease Disease P49815 R905W Disease Disease P49815 M449I Disease Neutral P49815 L1027P Disease Disease P49815 M895V Disease Disease P49815 V1673L Neutral Disease P49815 D1295V Disease Neutral P49815 G1787S Neutral Neutral P49815 C227Y Disease Disease P49815 L160V Neutral Neutral P49815 D1084E Disease Neutral P49815 P1709L Disease Disease P49815 H1620Y Disease Disease P49815 D1636N Neutral Neutral P49815 M286V Neutral Neutral P49815 A862V Neutral Neutral P49815 A536V Neutral Neutral P49815 R261W Neutral Disease P49815 A1712E Disease Disease P49815 T94P Neutral Neutral P49815 G1791S Neutral Neutral P49815 Y407D Disease Neutral P49815 K599M Disease Neutral P49815 N1643I Disease Disease P49815 L826M Disease Neutral P49815 H593R Neutral Disease P49815 A1429S Neutral Neutral P49815 H1773P Disease Neutral P49815 R611W Disease Disease P49815 L717R Disease Disease P49815 I463V Neutral Neutral P49815 S1282G Neutral Neutral P49815 R905Q Disease Disease P49815 G440S Neutral Neutral P49815 A583T Neutral Disease P49815 R367Q Neutral Neutral P49815 P1315S Disease Neutral P49815 V1144M Disease Neutral P49815 G294E Disease Disease P49815 S1653F Disease Disease P49815 P1675L Disease Disease P49815 L1750F Disease Neutral P49815 L1744P Disease Disease P49815 N1651S Disease Neutral P49815 C696Y Disease Neutral P49815 N486I Disease Neutral P49815 R1200W Disease Disease P49815 S1498N Disease Disease P49815 N1681K Disease Disease P49815 K258N Disease Disease P49815 R611Q Disease Disease P49815 S1341R Neutral Neutral P49815 N331K Disease Disease P49815 P1497R Disease Disease P49815 V769E Disease Disease P49815 D647N Disease Neutral P49815 R1329H Disease Neutral P49815 D1690Y Disease Disease P49815 S1704T Disease Disease P49815 P378L Neutral Neutral P49815 F320L Disease Neutral P49815 P1227L Disease Neutral Q00597 S26F Neutral Neutral Q00597 L496R Disease Disease Q00597 G139E Neutral Disease Q00597 L554P Disease Disease Q00597 Q465R Neutral Neutral Q00597 I312V Neutral Neutral Q00597 I80T Neutral Neutral Q00597 V449M Neutral Neutral Q00597 L190F Neutral Neutral Q00597 D195V Disease Disease O95838 R523H Neutral Neutral O95838 D470N Neutral Neutral O95838 H22L Neutral Neutral Q96Q04 L929V Neutral Neutral Q92851 A414V Disease Neutral Q92851 Y446C Neutral Disease Q92851 I406L Disease Neutral Q92851 L285F Disease Neutral Q92851 V410I Neutral Neutral Q92851 M147T Disease Neutral Q8NEY4 N143D Neutral Disease Q8N5A5 S61R Neutral Neutral P05155 A456E Disease Disease P05155 R466S Disease Disease P05155 P498R Disease Disease P05155 A465V Disease Neutral P05155 T308S Neutral Disease P05155 C130Y Disease Disease P05155 V480M Neutral Neutral P05155 P498S Disease Disease P05155 A458V Disease Disease P05155 P489R Disease Neutral P05155 Q474E Neutral Disease P05155 D39E Neutral Neutral P05155 G345R Disease Disease P05155 R466C Disease Disease P05155 L481R Disease Disease P05155 L481P Disease Disease P05155 V56A Neutral Neutral P05155 G429R Disease Disease P05155 G493E Disease Disease P05155 V473E Disease Disease P05155 V454E Disease Disease P05155 T394P Disease Neutral P05155 R466L Disease Disease P05155 A458T Disease Disease P05155 F477S Disease Disease P05155 V473M Disease Neutral P05155 D408V Disease Disease P05155 R466H Disease Disease P05155 T467P Disease Neutral Q9NSE4 I522V Neutral Neutral Q6PJQ5 V286A Neutral Neutral Q8TES7 G65V Neutral Neutral Q8TES7 P371S Neutral Neutral Q8TES7 C574S Neutral Neutral Q8TES7 R151G Neutral Neutral P48643 H147R Disease Disease Q8IYB7 P12S Neutral Neutral P51582 N178T Neutral Neutral P51582 P191L Neutral Neutral P51582 V168M Neutral Neutral Q03001 K1319N Neutral Neutral P56539 V57M Disease Disease P56539 P29L Disease Disease P56539 T64S Disease Neutral P56539 T64P Disease Disease P56539 N33K Disease Disease P56539 R27Q Disease Disease P56539 V44E Disease Disease P56539 L87P Disease Disease P56539 A46V Disease Disease P56539 D28E Disease Disease P56539 P105L Disease Disease P56539 G56S Disease Neutral P56539 A93T Disease Disease P56539 R126H Neutral Neutral P56539 A46T Disease Disease P56539 S53G Disease Disease P56539 C72W Disease Neutral Q8TBZ9 D48H Neutral Neutral Q8TBZ9 I126V Neutral Neutral Q8TBZ9 E221K Neutral Neutral Q8TBZ9 C186S Neutral Neutral Q8TBZ9 E221A Neutral Neutral Q86XE0 S354Y Neutral Neutral Q86XE0 A282V Neutral Disease Q86XE0 H155N Neutral Neutral Q9H611 I640N Neutral Neutral Q8NFM7 T255M Neutral Neutral Q8NFM7 V301M Neutral Neutral Q9UJN7 G59C Neutral Neutral Q9UJN7 K51R Neutral Neutral P50281 S8P Neutral Neutral P51511 G609R Neutral Neutral P50281 R431H Neutral Disease P51511 R622W Neutral Neutral P50281 M355I Neutral Disease P51511 P350L Neutral Neutral P50281 D273N Neutral Neutral P51511 D596G Neutral Neutral P51511 L200P Neutral Disease P50281 I233V Neutral Neutral P50281 R6K Neutral Neutral P50281 R302W Neutral Neutral P50281 A4T Neutral Neutral P49005 N303S Neutral Neutral Q96PX8 L552M Neutral Neutral Q9UBK8 C432R Disease Disease Q9UBK8 G581R Disease Disease Q9UBK8 S284T Neutral Neutral Q9UBK8 P477R Neutral Disease Q9UBK8 L202S Neutral Neutral Q9UBK8 L360V Neutral Neutral Q9UBK8 K377R Neutral Neutral Q9UBK8 H622Y Neutral Neutral Q9UBK8 I49M Neutral Neutral Q9UBK8 G514R Disease Disease Q9UBK8 A156T Disease Disease Q9UBK8 V83M Disease Disease Q9UBK8 R442C Neutral Disease Q8TF40 I844V Neutral Neutral Q8TF40 V738L Neutral Neutral Q8TF40 Q648R Neutral Neutral Q8TF40 S354L Neutral Disease Q8TF40 C76G Neutral Neutral Q5HYK3 A152T Neutral Disease Q8N1I0 P1718L Disease Neutral Q8N1I0 E606Q Neutral Neutral Q8N1I0 P1733A Neutral Neutral Q8N1I0 P1917L Neutral Neutral Q8N1I0 S1926L Neutral Neutral Q8N1I0 V1884M Disease Neutral Q8N1I0 T87I Disease Neutral Q8N1I0 K1059T Disease Disease Q8N1I0 S1755P Disease Neutral Q92608 S1746T Neutral Neutral Q8N1I0 V1914I Neutral Neutral Q92608 T1779S Neutral Neutral Q9H7D0 E1836K Neutral Neutral Q9H7D0 Q250R Neutral Neutral Q9UKA4 S721C Neutral Neutral O00587 R302C Neutral Neutral Q9UHC7 V243L Neutral Disease Q15572 T791M Neutral Neutral Q15572 H518Y Neutral Disease Q15572 P793L Neutral Neutral Q15572 A591G Neutral Neutral Q15572 P573L Neutral Neutral Q15572 S387L Neutral Neutral Q15572 S304F Neutral Neutral Q15572 G635S Neutral Neutral Q15572 R816H Neutral Neutral Q15572 R357H Neutral Neutral Q15572 L575M Neutral Neutral O00241 M229I Neutral Disease O00241 R53H Neutral Neutral O00241 P363A Neutral Neutral O00241 R23G Neutral Neutral P51878 V201L Neutral Neutral P51878 R152H Neutral Neutral P51878 F13L Neutral Neutral Q9Y6E0 A414V Neutral Neutral Q9Y6E0 L426I Neutral Neutral Q13233 C443S Neutral Disease Q13233 S92N Neutral Neutral A4D1P6 L257P Neutral Neutral P35070 C7G Neutral Neutral P35070 L124M Neutral Neutral O60602 N592S Neutral Neutral O60602 P112A Neutral Neutral O60602 F616L Neutral Neutral O60602 T82I Neutral Neutral Q9UMS6 T573A Neutral Neutral P60174 F241L Disease Disease P60174 G73A Disease Disease P60174 V232M Disease Disease P60174 E105D Disease Disease P60174 V155M Disease Neutral P60174 I171V Disease Neutral P60174 C42Y Disease Disease Q49AG3 P77S Neutral Neutral Q49AG3 A17V Neutral Neutral Q49AG3 Q47R Neutral Neutral O43913 R166C Neutral Disease O43913 G37R Neutral Disease O43913 K52N Neutral Neutral Q6VVB1 C26S Disease Disease Q6VVB1 P69A Disease Neutral Q6VVB1 L87P Disease Disease Q6VVB1 Q302P Disease Neutral Q6VVB1 F33S Disease Neutral Q6VVB1 D146N Disease Neutral Q6VVB1 P111L Neutral Neutral P56750 A82T Neutral Disease P56748 S151P Neutral Neutral Q8N6F1 L90P Disease Disease O95500 V85D Disease Disease Q8N6F1 Q57E Disease Disease Q8N6F1 L13F Neutral Disease O95471 A197V Neutral Neutral O95471 A133T Neutral Neutral P56748 T129A Neutral Neutral O95500 T4M Neutral Neutral Q8N6F1 G20D Disease Disease P56747 I143V Neutral Neutral Q96RS0 V576I Neutral Neutral Q96RS0 F754C Neutral Neutral Q96RS0 I511T Neutral Neutral Q96RS0 I160V Neutral Neutral Q96RS0 T16I Neutral Neutral Q14568 T235A Neutral Neutral Q14568 C312Y Neutral Neutral P17900 M69V Neutral Neutral P17900 C138R Disease Disease P17900 I59V Neutral Neutral P17900 A19T Neutral Neutral P17900 R169P Disease Disease Q92759 R337Q Neutral Disease Q14289 E970K Neutral Neutral Q14289 K838T Neutral Neutral Q14289 Q359E Neutral Neutral Q14289 L808P Neutral Disease Q14289 R698H Neutral Disease Q14242 M62I Neutral Neutral Q14242 P246S Neutral Neutral Q8IWX9 S100L Neutral Disease Q8IWX9 D160E Neutral Neutral Q8IWX9 I115V Neutral Neutral P01909 V73L Neutral Neutral P01907 M230V Neutral Neutral P01907 Q241R Neutral Neutral P01907 T49S Neutral Disease P01907 Y48F Neutral Neutral P01907 M18T Neutral Neutral P01907 V17M Neutral Neutral P01909 C70Y Neutral Disease P01909 I88M Neutral Disease P01909 T49S Neutral Disease P01909 R78S Neutral Neutral P01907 D25G Neutral Disease P01909 V229M Neutral Neutral P01907 F238L Neutral Disease P01907 C34Y Neutral Neutral P01907 R70Q Neutral Disease P01909 F237L Neutral Neutral P01907 Q57E Neutral Neutral P01907 A210T Neutral Neutral P01906 V227A Neutral Neutral P01903 V16L Neutral Neutral P01907 A11T Neutral Neutral P01909 L91V Neutral Disease P01907 L8M Neutral Neutral P01909 Q57E Neutral Neutral P01909 V73D Neutral Disease P01907 F41S Neutral Neutral P01909 Y48F Neutral Neutral P01909 R240Q Neutral Disease P01909 M8L Neutral Neutral P01909 T86R Neutral Neutral P01909 A11T Neutral Neutral P01909 S41F Neutral Disease P01907 Q152H Neutral Neutral P01903 V242L Neutral Neutral P01907 T130I Neutral Disease Q9BV79 L96F Neutral Neutral Q9GZM5 A5V Neutral Neutral Q8NFU5 M349I Neutral Neutral P52569 C376F Neutral Disease P52569 V20M Neutral Neutral P52569 A531T Neutral Neutral Q86X59 P186L Neutral Neutral Q9UMX9 V507L Neutral Disease Q9UMX9 D157N Disease Neutral Q9UMX9 A486V Disease Neutral Q9UMX9 P58S Disease Disease Q9UMX9 E272K Neutral Neutral Q9UMX9 P58A Disease Disease Q9UMX9 T500P Neutral Neutral Q9UMX9 G188V Disease Disease Q9UMX9 L374F Neutral Disease Q9UMX9 A477T Disease Disease Q9UMX9 L361P Disease Disease Q9UMX9 W202C Disease Disease Q9UMX9 Y317C Disease Disease Q9NVU0 S46A Neutral Neutral Q68CQ7 R210H Neutral Disease Q9UNA4 T706A Neutral Neutral Q9UNA4 I236M Neutral Disease Q9UNA4 E251K Neutral Disease Q9UNA4 F507S Neutral Disease Q9UNA4 R71G Neutral Disease Q9UNA4 H449R Neutral Neutral Q9UNA4 C535R Neutral Disease O95711 M160V Neutral Neutral O95711 S93P Neutral Neutral Q9UBC9 L149V Neutral Neutral Q9UBC5 F600L Neutral Neutral Q9UBC5 G662E Disease Neutral Q9UBC5 G674D Disease Disease Q9UBC5 S797F Disease Neutral Q9UBC5 S910P Disease Disease Q9UBC5 V306M Disease Neutral Q9UBC5 E385D Disease Disease Q9BYI3 L53P Disease Disease P10646 V292M Neutral Neutral P48552 V1079F Neutral Neutral P48552 H221R Neutral Neutral P48552 I441V Neutral Neutral P48552 R448G Neutral Neutral P48552 S803L Neutral Neutral P48552 Y315F Neutral Neutral O60447 Q612H Neutral Neutral O60447 V336I Neutral Neutral Q8NEU8 A433V Neutral Neutral Q9NX57 N134S Neutral Neutral Q9NR71 A346S Neutral Neutral Q9NR71 T51A Neutral Neutral Q96C45 S348G Neutral Neutral Q96C45 K39R Neutral Neutral Q96C45 A715T Neutral Neutral Q96C45 N139K Neutral Disease Q96C45 T415M Neutral Neutral Q96C45 A542T Neutral Neutral Q96C45 L603S Neutral Neutral Q96C45 K569R Neutral Neutral Q96C45 V18A Neutral Disease Q96C45 S640A Neutral Neutral Q96C45 S417P Neutral Disease Q96C45 S223N Neutral Neutral Q8WWZ3 E152K Disease Neutral Q8NBF1 F157L Neutral Neutral O95486 T302I Neutral Neutral O95486 T396M Neutral Neutral O95486 S261G Neutral Neutral Q9C000 M1119V Neutral Neutral Q9C000 V1059M Neutral Neutral Q9C000 M1184V Neutral Neutral Q9C000 T246S Neutral Neutral Q9C000 T878M Neutral Neutral Q9C000 R404Q Neutral Disease Q9C000 R1366C Neutral Neutral Q9C000 V1241L Neutral Neutral Q9C000 H1069Y Neutral Neutral Q9C000 L155H Neutral Neutral P03901 C32R Disease Disease P03901 M36I Neutral Disease P03901 V65A Disease Neutral P03901 I61T Neutral Disease P03901 N57S Neutral Neutral P28358 M319K Disease Disease Q8WW52 A416V Neutral Neutral Q8WW52 I119T Neutral Neutral Q8WW52 G546D Neutral Neutral Q8WW52 D51N Neutral Neutral Q8WW52 N87D Neutral Neutral Q8WW52 G526A Neutral Neutral P08138 S205L Neutral Neutral P42261 D487N Neutral Disease P39086 L902S Neutral Neutral P42262 Q608R Neutral Disease P39086 A332V Neutral Disease P42261 F588L Neutral Neutral P42261 I548M Neutral Disease P39086 A870V Neutral Neutral P42263 F525L Neutral Disease P39086 R862Q Neutral Disease P39086 I757V Neutral Neutral P42261 P521T Neutral Neutral P42261 A536S Neutral Neutral Q8NEW7 R92W Disease Disease Q8NEW7 R84W Disease Disease Q8NEW7 R81C Disease Disease P26718 A72T Neutral Neutral P26718 N177S Neutral Neutral Q5JPB2 G845R Neutral Neutral Q5JPB2 S1513P Neutral Neutral Q8N7M0 E49D Neutral Neutral Q9NPG4 H385N Neutral Neutral Q9NPG4 S640N Neutral Neutral P21731 C68S Neutral Neutral P21731 A160T Neutral Neutral P21731 E94V Neutral Disease P21731 V217I Neutral Neutral P21731 V80E Neutral Disease P21731 V176E Neutral Disease Q9UGK8 G457E Neutral Neutral Q9UGK8 K429E Neutral Neutral Q8IYL9 I231L Neutral Neutral O43149 P1972L Neutral Neutral O43149 Q2369E Neutral Neutral O43149 S1437A Neutral Neutral O43149 V30A Neutral Neutral O43149 V2014I Neutral Neutral O43149 L2303P Neutral Disease O43149 I1021V Neutral Neutral O43149 A2421T Neutral Neutral O43149 Y2301H Neutral Neutral O43149 P2051S Neutral Neutral P03923 M64V Disease Disease P03923 Y165C Neutral Disease P03923 V31A Neutral Neutral P03923 I58V Neutral Neutral P03923 Y59C Disease Disease P03923 A74V Disease Disease P03923 I33V Neutral Neutral P03923 G36S Disease Disease P03923 L60S Disease Disease P03923 I26M Disease Disease P03923 M64I Disease Disease P03923 A72V Disease Disease Q14D04 R365Q Neutral Neutral Q14D04 M319V Neutral Neutral Q14D04 L329V Neutral Neutral Q14D04 S271C Neutral Neutral Q14D04 S208C Neutral Neutral Q14D04 V263G Neutral Neutral Q14D04 S522P Neutral Neutral P05186 C489S Disease Disease P05186 A177T Disease Neutral P05186 V459M Disease Disease P05186 N170D Disease Neutral P05186 S445P Disease Disease P05186 F327G Disease Disease P05186 E298K Disease Neutral P05186 G339R Disease Disease P05186 R272H Disease Disease P05186 R391H Disease Disease P05186 G456R Disease Disease P05186 Y263H Neutral Neutral P05186 E235G Disease Disease P05186 M62L Disease Disease P05186 A51V Disease Disease P05186 A348T Disease Disease P05186 T411A Disease Disease P05186 T68M Disease Disease P05186 Y297D Disease Disease P05186 D306V Disease Disease P05186 S181L Disease Neutral P05186 D378V Disease Disease P05186 E354D Disease Neutral P05186 G473S Disease Disease P05186 G75S Disease Disease P05186 E291K Disease Neutral P05186 V423A Disease Neutral P05186 T134N Disease Neutral P05186 A51S Disease Disease P05186 Q76R Disease Disease P05186 D294Y Disease Neutral P05186 H171R Disease Disease P05186 E311K Disease Disease P05186 L289F Disease Disease P05186 H381R Disease Disease P05186 V382I Disease Neutral P05186 D294A Disease Disease P09923 H298L Neutral Neutral P05186 Y436H Disease Neutral P05186 A468T Disease Disease P05186 R450C Disease Disease P05187 P25L Neutral Disease P05186 D189E Disease Neutral P10696 L273M Neutral Neutral P05186 G491R Disease Disease P05186 R71H Disease Disease P05186 G249V Disease Disease P05186 G162V Disease Disease P05186 G220A Disease Disease P05186 I490F Disease Disease P05186 G334D Disease Disease P05186 R246S Disease Disease P05186 G326R Disease Disease P05186 E476K Disease Disease P05186 H171Y Disease Disease P05186 G220V Disease Disease P05186 R272L Disease Disease P05186 R223Q Disease Disease P05186 Q207P Disease Disease P05186 T148I Disease Neutral P05186 P108L Disease Disease P05186 R152H Disease Neutral P05186 C201Y Disease Disease P05186 S17F Disease Neutral P05186 M295T Disease Disease P05186 E191G Disease Disease P10696 Q34E Neutral Neutral P05186 R450H Disease Neutral P05186 G63V Disease Disease P05186 K224E Disease Neutral P05186 F327L Disease Disease P05186 I212F Disease Disease P05186 N211D Disease Disease P05186 R71P Disease Disease P05186 R136H Disease Neutral P05186 G426D Disease Disease P05186 A399S Disease Neutral P05186 E452K Disease Disease P05186 V522A Neutral Neutral P05186 R391C Disease Disease P05186 A111T Disease Disease P05186 G63R Disease Disease P05186 A33V Disease Disease P05186 Y28C Disease Disease P05186 R71S Disease Disease P05186 N417S Disease Disease P05186 N478I Disease Disease P05186 G162S Disease Disease P05186 A116T Disease Disease P05186 G120R Disease Disease P05186 R184W Disease Disease P05186 T134H Disease Neutral P05186 G426C Disease Disease P05186 E191K Disease Neutral P05186 M62V Disease Disease P05186 A114G Disease Disease P05186 A179T Disease Disease P10696 L316R Neutral Disease P05186 G129R Disease Disease P05186 A176T Disease Disease P05186 L414M Disease Neutral P05186 V128M Disease Neutral P05186 L275P Disease Disease P05186 L299P Disease Disease P05186 R71C Disease Disease P05186 A132V Disease Neutral P10696 G527E Neutral Neutral P05186 A40V Disease Neutral P05186 D406G Disease Disease P05186 R223W Disease Disease P05186 P292T Disease Neutral O75900 F91L Neutral Neutral Q16363 H498Y Neutral Neutral Q16363 P1119R Neutral Disease Q16363 S1117G Neutral Neutral Q9C0K1 A391T Neutral Disease Q15043 P33L Neutral Neutral Q86YJ5 Q257H Neutral Neutral Q86YJ5 T307P Neutral Neutral Q8WXU2 A332V Neutral Disease Q8WXU2 N38K Neutral Neutral Q8WXU2 G191E Neutral Neutral Q8WXU2 S420C Neutral Neutral Q8WXU2 V91I Neutral Neutral Q8WXU2 P2S Neutral Neutral Q96GC5 E6G Neutral Neutral Q08334 K47E Neutral Neutral Q9BT25 G83R Neutral Neutral P10244 S427G Neutral Neutral Q13705 P176R Neutral Neutral Q13705 R40H Disease Neutral Q13705 V494I Disease Neutral Q8IW93 E238Q Neutral Neutral Q8IW93 G163R Neutral Disease P51674 V242L Neutral Neutral Q5TD97 V211M Neutral Disease Q15361 R401Q Neutral Neutral Q15361 E35K Neutral Neutral Q15361 V303A Neutral Neutral Q15361 G360V Neutral Neutral Q15361 A290S Neutral Neutral Q99645 S150C Neutral Disease Q8N196 A158T Disease Neutral Q8N196 P635S Neutral Neutral Q8N196 A296T Disease Neutral Q8N196 T552M Disease Neutral Q8N196 V693M Neutral Neutral Q8N196 L556V Neutral Neutral Q8N196 G365R Disease Neutral Q8IV53 A23T Neutral Neutral Q8IV53 R489C Neutral Neutral Q8IV53 A542V Neutral Neutral O75360 R73H Disease Disease O75360 R73C Disease Disease O75360 R120C Disease Disease O75360 F117I Disease Disease O75360 A142T Neutral Neutral P29274 A50V Neutral Neutral P29274 R300H Neutral Disease P29274 G392R Neutral Neutral P00846 V213I Neutral Neutral P00846 A80T Neutral Neutral P00846 F117L Neutral Neutral P00846 T112A Neutral Neutral P00846 L37P Neutral Disease P00846 T59A Neutral Neutral P00846 T53I Neutral Neutral P00846 L217P Disease Disease P00846 I204T Neutral Neutral P00846 G16S Neutral Disease P00846 T133A Neutral Neutral P00846 S182L Neutral Neutral P00846 H61Y Neutral Neutral P00846 F193L Neutral Neutral P00846 L156R Disease Disease P00846 S219G Neutral Neutral P00846 A11T Neutral Disease P00846 I192V Neutral Neutral P00846 I14V Neutral Neutral P00846 M60T Neutral Neutral P00846 A7T Neutral Disease P00846 I121V Neutral Neutral P00846 T33S Neutral Neutral P00846 I192T Disease Neutral P00846 A155T Neutral Neutral P00846 A177T Neutral Neutral P00846 H90Y Neutral Neutral P00846 L156P Disease Disease P00846 T178A Neutral Neutral Q9H422 Q142R Neutral Neutral Q9H422 C191R Neutral Disease Q9H422 S500N Neutral Disease Q9H422 P729L Neutral Neutral Q9H422 G170E Neutral Neutral O94804 R322W Neutral Disease O94804 M710T Neutral Neutral O94804 S853L Neutral Neutral O94804 K277E Disease Disease O94804 T336I Neutral Neutral O94804 R268C Neutral Neutral O94804 S905T Neutral Neutral O94804 C947Y Neutral Disease O94804 N467S Neutral Neutral Q14642 K45R Neutral Neutral Q9UF12 R525Q Neutral Disease Q9UF12 P91R Neutral Neutral Q6ZNG2 V171M Neutral Neutral P60602 A28P Neutral Neutral Q5FWF5 T221M Neutral Neutral Q9NS91 E6A Neutral Neutral Q9NS91 Q302R Neutral Neutral Q9NS91 I307V Neutral Neutral Q96IZ0 G137A Neutral Neutral Q96IZ0 P78R Neutral Neutral Q96IZ0 P42L Neutral Neutral Q96IZ0 E202A Neutral Neutral Q06124 N58K Disease Disease Q06124 T73I Disease Disease Q06124 D61N Disease Disease Q06124 E69Q Disease Disease Q06124 R502L Disease Disease Q06124 T42A Disease Neutral Q06124 A72G Disease Neutral Q06124 R502W Disease Disease Q06124 Q510R Disease Disease Q06124 G507R Disease Neutral Q06124 G468A Disease Disease Q06124 F71K Disease Disease Q06124 Y62D Disease Disease Q06124 A465T Disease Disease Q06124 E76D Disease Neutral Q06124 G507A Disease Neutral Q06124 E76V Disease Disease Q06124 Q256R Disease Neutral Q06124 I282V Disease Neutral Q06124 N308D Disease Disease Q06124 Q79P Disease Disease Q06124 E76G Disease Disease Q06124 L564F Disease Neutral Q06124 E76K Disease Disease Q06124 Q510P Disease Disease Q06124 F285L Disease Neutral Q06124 D61V Disease Disease Q06124 S506T Disease Neutral Q06124 E139D Disease Neutral Q06124 T2I Disease Neutral Q06124 F285S Disease Neutral Q06124 R505K Disease Disease Q06124 A72V Disease Neutral Q06124 M508V Disease Neutral Q06124 A72S Disease Neutral Q06124 Q79R Disease Neutral Q06124 A72T Disease Neutral Q06124 D61G Disease Disease Q06124 N308S Disease Neutral Q06124 Y279C Disease Disease Q06124 D61Y Disease Disease Q06124 D106A Disease Neutral Q06124 Y63C Disease Disease Q06124 T472M Disease Disease Q06124 E69K Disease Neutral Q06124 T415M Disease Neutral Q06124 I309V Disease Neutral Q06124 G60A Disease Disease Q06124 Y279S Disease Neutral Q06124 E76A Disease Neutral Q06124 Q514P Disease Disease Q9UL59 L128H Neutral Neutral Q9UL59 I185R Neutral Neutral O15344 L626P Disease Disease O15344 I536T Disease Disease O15344 L295P Disease Disease O15344 C266R Disease Disease Q13360 T112M Neutral Neutral Q6ZN79 K142Q Neutral Neutral Q13360 D94G Neutral Neutral Q01831 K928Q Neutral Neutral Q01831 L48F Neutral Neutral Q01831 L16V Neutral Neutral Q01831 R671H Neutral Neutral Q01831 P334H Disease Neutral Q01831 T689M Neutral Neutral Q01831 K939Q Neutral Neutral Q01831 K86R Neutral Neutral Q01831 V499A Neutral Neutral Q01831 M513I Neutral Neutral Q01831 Q632E Neutral Neutral Q01831 R314Q Neutral Neutral Q01831 R492H Neutral Neutral Q8IX01 S206G Neutral Neutral Q9Y6H8 N63S Disease Disease P48165 I247M Disease Neutral Q9Y6H8 F32L Disease Disease Q9Y6H8 M299L Neutral Neutral Q9Y6H8 P187L Disease Disease P48165 V64G Disease Disease P48165 R198Q Disease Disease Q9Y6H8 R76H Disease Disease P48165 E48K Disease Disease P48165 V44E Disease Disease P48165 P88S Disease Disease Q96FE5 S183F Neutral Neutral Q7L985 R507H Neutral Neutral Q9UHI8 A227P Neutral Neutral Q5T686 G41A Neutral Neutral Q9NZV5 T137A Neutral Neutral Q9NZV5 C142Y Neutral Neutral Q9NZV5 K502N Neutral Neutral P25021 N217D Neutral Neutral P25021 K231R Neutral Neutral P25021 V268M Neutral Neutral Q01534 P195R Neutral Neutral Q01534 I216F Neutral Disease Q9Y5S1 G17A Neutral Neutral Q8IX21 S541Y Neutral Neutral O60931 G308R Disease Disease O60931 G169D Disease Disease O60931 Q222R Disease Disease O60931 S139F Disease Disease O60931 L338P Disease Disease O60931 D305G Disease Disease O60931 P200L Disease Disease O60931 V42I Disease Neutral O60931 W182R Disease Disease O60931 N288K Disease Disease O60931 G197R Disease Disease O60931 D305Y Disease Disease O60931 N177T Disease Disease O60931 S298N Disease Disease O60931 D205N Disease Disease O60931 L158P Disease Disease O60931 D346N Disease Disease O60931 I133F Disease Disease O60931 K292R Disease Disease O60931 N323K Disease Neutral O60931 K280R Disease Disease O60931 G339R Disease Disease O60931 G110V Disease Disease Q96I15 F276S Neutral Neutral Q96I15 K52E Neutral Disease Q96I15 A175T Neutral Neutral Q9H6Y2 R50C Neutral Disease Q9H6Y2 R151C Neutral Disease Q9H6Y2 S210F Neutral Neutral Q9H6Y2 Y235C Neutral Disease P0C263 E20K Neutral Neutral P0C263 A41E Neutral Neutral P0C263 G102D Neutral Neutral O95976 N186K Neutral Neutral O95976 F173S Neutral Disease O95976 Q74R Neutral Neutral O43822 T150I Neutral Neutral Q8IXW0 T44A Neutral Neutral Q15491 G46R Neutral Neutral Q9NR99 L2531V Neutral Neutral Q9NVE4 F217L Neutral Neutral Q8IYX7 P63S Neutral Neutral Q8IYX7 K27E Neutral Neutral Q9C0C6 L31F Neutral Neutral Q96PW8 V431I Neutral Neutral O75822 A141T Neutral Neutral P28698 I331V Neutral Neutral P52789 A314P Neutral Disease Q2TB90 R721W Neutral Disease P19367 L529S Disease Disease Q2TB90 T124I Neutral Disease Q2TB90 D54G Neutral Disease P52789 D881N Neutral Neutral P52789 A314V Neutral Neutral P52789 T331I Neutral Neutral P52789 L148F Neutral Disease P52789 R844K Neutral Neutral P52789 R775Q Neutral Neutral P52789 Q142H Neutral Neutral Q2TB90 L204P Neutral Disease P52789 R801Q Neutral Disease P52789 R497Q Neutral Neutral P19367 T680S Disease Disease Q2TB90 N917K Neutral Neutral P19367 L776M Neutral Disease P52789 R274C Neutral Disease P52789 A387S Neutral Disease P52789 R353C Neutral Disease P12235 L98P Disease Disease P12235 D104G Disease Disease P12235 A90D Disease Disease P05141 R111L Neutral Disease P12235 V289M Disease Disease P12235 A114P Disease Disease Q6ZRM9 F205L Neutral Neutral Q6ZRM9 V158M Neutral Neutral Q6ZRM9 A149V Neutral Neutral Q6H3X3 T70R Neutral Disease Q5GAN3 S139A Neutral Neutral Q14188 P81S Neutral Neutral Q14188 I64T Neutral Disease Q14186 D401N Neutral Neutral Q14721 P825S Neutral Neutral Q99759 A325G Neutral Neutral Q99759 V281M Neutral Neutral Q99759 A435G Neutral Neutral Q16585 M100K Disease Disease Q16585 L108R Disease Disease Q16585 I119F Disease Neutral Q16585 G167S Disease Neutral Q16585 T151R Disease Neutral Q16585 R91L Disease Disease Q16585 R91P Disease Disease Q16585 R91C Disease Disease Q92681 N271S Neutral Neutral Q92681 C191W Neutral Disease Q92681 F62L Neutral Neutral O00175 I29L Neutral Neutral Q9H0K4 A50V Neutral Neutral Q8NEG0 M71V Neutral Neutral Q8NEG0 R30G Neutral Disease P22735 R389H Disease Disease P22735 R323Q Disease Disease P22735 N289T Disease Disease P22735 R143C Disease Disease P22735 R396L Disease Disease P22735 D802V Neutral Disease P22735 R142H Disease Disease P22735 D102V Disease Disease P22735 R307W Disease Disease P22735 D132N Neutral Neutral P22735 R143H Disease Disease P22735 S42Y Disease Neutral P22735 G218S Disease Disease P22735 V379L Disease Disease Q5SXH7 V337I Neutral Neutral Q13867 I443V Neutral Neutral Q96LB9 G126S Neutral Neutral Q96LA9 S83L Neutral Neutral Q96LA9 N25K Neutral Neutral Q96LB2 I36V Neutral Neutral Q96LB1 N16H Neutral Disease Q96LA9 F8L Neutral Neutral Q96LB1 F78L Neutral Disease Q96LB1 N62S Neutral Neutral Q96LA9 Y54C Neutral Disease Q96LB0 C82R Neutral Neutral Q96LA9 A182V Neutral Neutral Q96LB0 D169N Neutral Neutral Q92806 A366V Neutral Neutral Q02535 A105T Neutral Neutral Q02535 S111A Neutral Neutral O96002 S36A Neutral Neutral O15054 S305L Neutral Neutral Q8N5D6 D200N Neutral Disease Q8N5D6 L20F Neutral Neutral Q8N5D6 T248I Neutral Neutral Q8N5D6 L79P Neutral Disease Q8N5D6 S21G Neutral Neutral Q8N5D6 R163W Neutral Disease Q8N5D6 I291F Neutral Disease Q8N5D6 Q238P Neutral Disease P26998 R105Q Neutral Disease P26998 G165R Disease Disease P26998 V159I Neutral Neutral P26998 D113H Neutral Disease Q32MQ0 M235V Neutral Neutral O14656 D264H Neutral Disease O14656 D216H Neutral Neutral Q5T5J6 H536R Neutral Neutral Q5T5J6 N821D Neutral Neutral Q5T5J6 L638F Neutral Neutral Q5T5J6 I148V Neutral Neutral Q8NHY6 A620V Neutral Neutral Q6PF06 V234G Neutral Disease Q6PF06 V242A Neutral Neutral P41229 E698K Disease Disease P41229 L731F Disease Disease P41229 D402Y Disease Disease Q9BY66 V1186L Neutral Neutral P41229 R750W Disease Disease P41229 A388P Disease Disease P41229 F642L Disease Disease P41229 Y751C Disease Disease P41229 D87G Disease Disease P41229 S451R Disease Disease P21266 V224I Neutral Neutral P09488 K173N Neutral Neutral P09211 A114V Neutral Disease P09211 I105V Neutral Neutral Q03013 S2P Neutral Neutral Q03013 A160V Neutral Neutral P09488 S210T Neutral Neutral Q8N9B5 A592V Neutral Neutral Q8N9B5 M364L Neutral Neutral Q8N9B5 H720R Neutral Neutral Q9Y4G2 R377H Neutral Neutral Q9P1W9 G138D Neutral Neutral Q9P1W9 I280V Neutral Neutral Q9HCR9 R804H Neutral Disease Q9HCR9 R867G Neutral Disease Q8N1W0 V458A Neutral Neutral Q8N1W0 G363D Neutral Neutral Q8N1W0 P419S Neutral Neutral P01833 T555I Neutral Disease P01833 G365S Neutral Disease P01833 A580V Neutral Neutral Q96J77 L118F Neutral Neutral Q9Y6D5 E209K Disease Neutral Q9H222 M622V Neutral Neutral Q9H222 C600Y Neutral Disease Q9H222 R419H Disease Disease Q9H222 Q604E Neutral Neutral Q9H222 R389H Disease Disease Q9H222 N437K Disease Disease Q9H222 I523V Neutral Neutral Q9H222 R550S Disease Neutral Q9H222 E146Q Disease Disease Q9H222 R419P Disease Disease Q9H222 T517S Neutral Neutral Q8WUA8 S248N Neutral Neutral Q8WUA8 V308I Neutral Neutral Q8WUA8 D344E Neutral Neutral Q8WUA8 R208C Neutral Disease P15248 T117M Neutral Neutral Q9ULG6 G553D Neutral Neutral Q9ULG6 S44P Neutral Neutral Q9ULG6 A517D Neutral Neutral Q9ULG6 G553S Neutral Neutral Q9ULG6 A477V Neutral Neutral Q9ULG6 E161V Neutral Neutral Q9ULG6 Y418H Neutral Neutral Q9ULG6 T646I Neutral Neutral Q9ULG6 H673R Neutral Neutral Q9ULG6 R436L Neutral Neutral Q9ULG6 N590K Neutral Neutral Q9ULG6 K627E Neutral Neutral Q5VU43 R25L Neutral Disease Q5VU43 I49T Neutral Disease Q5VU43 N13S Neutral Neutral Q5VU43 A167T Neutral Neutral Q9BXC9 N70S Disease Neutral Q9BXC9 A504V Neutral Neutral Q9BXC9 R643H Disease Neutral Q9BXC9 R315Q Disease Disease Q9BXC9 L349W Disease Neutral Q9BXC9 R632P Disease Disease Q9BXC9 A122V Neutral Neutral Q9BXC9 V75G Disease Disease Q9BXC9 R23P Disease Disease Q9BXC9 D174E Disease Neutral Q9BXC9 T558I Disease Neutral Q9BXC9 D104A Disease Neutral Q9BXC9 R315W Disease Disease Q9BXC9 I123V Neutral Neutral Q9Y2J4 D731E Neutral Neutral Q96MS0 R703P Disease Disease Q96MS0 G361E Disease Neutral Q96MS0 Q1369R Neutral Neutral Q96MS0 E319K Disease Neutral Q96MS0 L5P Disease Disease Q96MS0 S705P Disease Neutral Q96MS0 V423M Neutral Neutral Q96MS0 I66L Disease Disease Q15526 Y274D Disease Disease Q15526 G124R Disease Disease Q15526 I246T Disease Disease Q15526 G124E Disease Disease Q8N0V4 Q452R Neutral Neutral O95970 S473L Disease Disease O95970 C42G Disease Disease O95970 C46R Disease Disease O95970 L26R Disease Disease O95970 E383A Disease Disease O95970 F318C Disease Disease Q8N0V4 R444Q Neutral Neutral Q86VZ4 P92R Neutral Neutral Q86VZ4 R351H Neutral Neutral Q92576 H1834Y Neutral Neutral P42684 P996R Neutral Neutral P42684 K930R Neutral Neutral P42684 V946M Neutral Neutral P42684 T1101A Neutral Neutral P42684 S1085N Neutral Neutral Q9P266 A1095G Neutral Neutral Q9P266 R957G Neutral Neutral Q9P266 E487D Neutral Neutral Q9P266 S1002T Neutral Neutral Q9P266 D494N Neutral Neutral Q9P266 E729A Neutral Neutral P06858 A427T Neutral Neutral P06858 S199C Disease Neutral P06858 A288T Neutral Disease P06858 P234L Disease Disease P06858 N318S Disease Neutral P06858 L392V Disease Neutral P06858 D36N Neutral Disease P06858 G222E Disease Disease P06858 T379A Neutral Neutral P06858 R102S Disease Neutral P06858 V370M Neutral Neutral Q13201 T805A Neutral Neutral Q13201 T58A Neutral Neutral Q13201 T964R Neutral Neutral Q13201 G883D Neutral Neutral Q8N511 V158I Neutral Neutral Q8N511 L166V Neutral Neutral Q9ULE3 H156P Neutral Disease Q9ULE3 E729K Neutral Neutral Q9ULE3 I777T Neutral Neutral Q6P5S2 C308G Neutral Disease Q01638 A78E Neutral Neutral P46459 T476M Neutral Disease Q96B96 G107S Neutral Neutral Q96B96 D154E Neutral Neutral O95239 L422W Neutral Disease Q92766 G1384R Neutral Neutral Q92766 G195R Neutral Neutral Q92766 G783V Neutral Disease Q92766 L1467P Neutral Neutral Q92766 D1171N Neutral Neutral Q92766 S1499Y Neutral Neutral P19419 G144S Neutral Neutral P19419 S183N Neutral Neutral O14960 V58I Neutral Neutral Q9GZW5 P110T Neutral Disease Q9GZW5 A185T Neutral Neutral Q13888 V236L Neutral Neutral Q13888 I151M Neutral Neutral Q8N0Z8 R103Q Neutral Neutral Q8NEV8 M512L Neutral Neutral Q8NEV8 R328Q Neutral Neutral Q8NEV8 L853P Neutral Neutral Q8NEV8 D1240N Neutral Neutral Q8NEV8 D1967N Neutral Disease Q8NEV8 V525F Neutral Disease Q8NEV8 N676S Neutral Neutral Q8NEV8 D777N Neutral Neutral Q8NEV8 E137V Neutral Neutral Q8NEV8 R1663G Neutral Neutral Q8NEV8 C1311R Neutral Neutral Q8NEV8 R19G Neutral Disease Q8NEV8 V899A Neutral Neutral Q8NEV8 R118L Neutral Neutral Q8NEV8 N892Y Neutral Neutral Q86X24 T267I Neutral Neutral Q8IXJ9 P815L Neutral Neutral Q8IXJ9 L1325F Neutral Neutral A4D256 I296L Neutral Disease A4D256 P238S Neutral Neutral Q15466 R57W Disease Neutral Q15466 R213C Disease Disease Q15466 G189E Disease Neutral Q15466 A195S Disease Neutral Q9NVX7 D330N Neutral Neutral P51161 T79M Neutral Neutral P07148 T94A Neutral Neutral P51161 S55Y Neutral Disease P07148 A54T Neutral Neutral P51161 R33H Neutral Disease P24539 T152N Neutral Neutral P24539 T152M Neutral Neutral O60779 S143F Disease Disease O60779 G172D Disease Disease O60779 D93H Disease Disease Q7Z3C6 S592G Neutral Neutral Q8NEH6 Y244H Neutral Neutral Q8NEH6 E426G Neutral Neutral Q8NEH6 C10Y Neutral Neutral Q8NEH6 Q55P Neutral Disease Q8NEH6 I216T Neutral Neutral Q14154 A95T Neutral Neutral Q14154 A247T Neutral Neutral Q14154 F128L Neutral Neutral Q14154 R468C Neutral Neutral Q14152 E386K Neutral Disease Q96H22 D84E Neutral Neutral Q9H583 N1967D Neutral Neutral Q9H583 N1694S Neutral Neutral Q9H583 E2017G Neutral Neutral Q9H583 V1854A Neutral Neutral O95450 V245I Neutral Neutral O95450 P1177S Neutral Neutral Q969P6 R525W Neutral Neutral Q9NSI5 R49T Neutral Neutral Q9NSI5 R170W Neutral Neutral Q9NSI5 N156K Neutral Neutral Q9NSI5 D350E Neutral Neutral Q8NFZ5 A396V Neutral Neutral O75914 A380E Disease Disease O75914 R67C Disease Disease Q8WX93 M224I Neutral Neutral Q8WX94 R693P Disease Disease Q8WX94 V319I Neutral Neutral Q8WX94 R693W Disease Disease Q8WX94 N913S Disease Disease Q8WX94 T971A Neutral Neutral P22033 A377E Disease Disease P22033 G94R Disease Disease P22033 N189K Disease Disease P22033 R228Q Disease Neutral P22033 Y316C Disease Disease P22033 I69V Neutral Neutral P22033 A197E Disease Disease P22033 T566R Disease Disease P22033 R108H Disease Disease P22033 G203R Disease Disease P22033 Y231N Disease Disease P22033 D640Y Disease Disease P22033 G623R Disease Disease P22033 A191E Disease Disease P22033 S148L Disease Disease P22033 V633G Disease Disease P22033 R108G Disease Disease P22033 L617R Disease Disease P22033 M700K Disease Disease P22033 G312V Disease Disease P22033 Q218H Disease Disease P22033 G703R Disease Disease P22033 G637R Disease Disease P22033 D156N Disease Disease P22033 A137V Disease Disease P22033 P86L Disease Disease P22033 L328P Disease Disease P22033 H678R Disease Disease P22033 M186V Disease Disease P22033 Q293P Disease Disease P22033 T370P Disease Disease P22033 H627R Disease Disease P22033 C560Y Disease Disease P22033 F573S Disease Disease P22033 L518P Disease Disease P22033 G717V Disease Disease P22033 G158V Disease Disease P22033 R616C Disease Disease P22033 A499T Neutral Neutral P22033 R369H Disease Disease P22033 P615R Disease Disease P22033 F638I Disease Disease P22033 R369C Disease Disease P22033 L281S Disease Disease P22033 R93H Disease Disease P22033 G427D Disease Disease P22033 G642R Disease Disease P22033 L347R Disease Disease P22033 G145S Disease Disease P22033 K621N Disease Disease P22033 V368D Disease Disease P22033 G87E Disease Disease P22033 G637E Disease Disease P22033 P615T Disease Disease P22033 N388H Disease Disease P22033 G215S Disease Disease P22033 G630E Disease Disease P22033 V669E Disease Disease P22033 F174S Disease Disease P22033 R532H Neutral Neutral P22033 G648D Disease Disease P22033 P95R Disease Disease P22033 N219Y Disease Disease P22033 L305S Disease Disease P22033 R694W Disease Disease P22033 V671I Neutral Neutral P22033 G215C Disease Disease P22033 L328F Disease Disease P22033 G626C Disease Disease P22033 H350Y Disease Disease P22033 S306F Disease Disease P22033 H386N Disease Disease P22033 H265Y Disease Disease P22033 G291E Disease Disease P22033 S262N Disease Disease P22033 G94V Disease Disease P22033 A535P Disease Disease P22033 Q109R Disease Disease P22033 Y587C Disease Disease P22033 T230I Disease Disease P22033 Q624R Disease Disease P22033 T598A Neutral Neutral P22033 A324T Disease Disease P22033 G426R Disease Disease P22033 R108C Disease Disease P22033 Q383H Disease Disease P22033 Q383P Disease Disease P22033 W105R Disease Disease P22033 L685R Disease Disease Q8IUR6 T483A Neutral Neutral Q96F25 V14M Neutral Neutral P06731 A340D Neutral Neutral P06731 E398K Neutral Neutral P06731 R664S Neutral Neutral Q93074 R963W Disease Neutral Q93074 N1009S Disease Neutral P28065 R60H Neutral Neutral Q9BXU8 Q120H Neutral Neutral P02792 A96T Disease Disease Q8IZQ1 I3032V Neutral Neutral Q9H306 W304L Neutral Disease P03956 I191V Neutral Neutral Q9H306 R22W Neutral Neutral P08254 K45E Neutral Neutral P22894 G154E Neutral Disease P22894 D193V Neutral Disease O60882 V275A Neutral Neutral P22894 V436A Neutral Disease P39900 G469R Neutral Neutral O60882 I169L Neutral Disease Q9H306 M24T Neutral Neutral P22894 S3C Neutral Neutral Q9H306 D447N Neutral Neutral P22894 K87E Neutral Neutral P45452 F75S Disease Disease Q9H306 V30M Neutral Neutral P03956 Q29P Neutral Disease P22894 N246Y Neutral Neutral Q9H306 E266V Neutral Neutral P22894 K460T Neutral Neutral Q9H306 I477V Neutral Neutral O60882 D139N Neutral Neutral P45452 D390G Neutral Neutral P22894 T32I Neutral Neutral P39900 N357S Neutral Neutral P03956 R405Q Neutral Neutral P45452 H2L Neutral Neutral O60882 T281P Neutral Disease O60882 T18K Neutral Neutral P03956 S406T Neutral Neutral P03956 D252G Neutral Disease O60290 I178T Neutral Neutral Q96PQ1 Y494S Neutral Disease Q96PQ1 P81T Neutral Disease Q96PQ1 T478M Neutral Neutral Q96PQ1 H217Q Neutral Neutral Q9BWE0 P88S Neutral Disease Q9BWE0 L14P Neutral Disease Q9BWE0 R92H Neutral Disease Q96EG3 Q153R Neutral Neutral Q9BWE0 A97V Neutral Neutral P50750 G231A Neutral Neutral P50750 F59L Neutral Disease Q16610 F167I Disease Disease Q16610 S535F Neutral Neutral Q16610 G528R Neutral Neutral Q16610 T130M Neutral Neutral Q16610 G415S Neutral Neutral Q13936 G406R Disease Disease Q13936 A2169T Neutral Neutral Q13936 A752T Neutral Disease Q13936 G402S Disease Disease P46100 Y2084H Disease Neutral P46100 R1742K Disease Neutral P46100 C1614R Disease Disease P46100 L192F Disease Disease P46100 P190S Disease Neutral P46100 C220Y Disease Disease P46100 V1552F Disease Disease P46100 C200S Disease Disease P46100 R246C Disease Disease P46100 V1538G Disease Disease P46100 R2271G Disease Neutral P46100 Y1847C Disease Disease P46100 L1645S Disease Neutral P46100 V194I Disease Neutral P46100 Q929E Neutral Neutral P46100 C243F Disease Disease P46100 G249C Disease Disease P46100 D2035V Disease Disease P46100 N1860S Neutral Neutral P46100 R246L Disease Disease P46100 N179S Disease Neutral P46100 Y2163C Disease Disease P46100 C220R Disease Disease P46100 G740E Neutral Neutral P46100 L409S Disease Disease P46100 K1650N Disease Neutral P46100 I2050T Disease Neutral P46100 P190L Disease Disease P46100 P190A Disease Disease P46100 G175E Disease Disease P46100 G249D Disease Disease P46100 W222S Disease Disease P46100 P1713S Disease Disease P46100 H1609R Disease Disease P46100 R2131Q Disease Disease P46100 P596S Neutral Neutral P46100 T1621M Disease Neutral P46100 Q219P Disease Neutral Q6JQN1 Q200R Neutral Neutral Q6JQN1 T216P Neutral Neutral Q6JQN1 A880V Neutral Neutral Q6JQN1 D463N Neutral Disease Q96DG6 Y155C Neutral Disease P50336 G232R Disease Disease P50336 R168C Neutral Disease P50336 R152C Disease Disease P50336 P256R Neutral Neutral P50336 R59W Disease Disease P50336 R304H Neutral Neutral Q96FF7 V340A Neutral Neutral P26885 C97Y Neutral Disease P26885 A25T Neutral Neutral Q6XZB0 G364E Neutral Disease Q6XZB0 D444E Neutral Neutral Q6XZB0 E431K Neutral Disease P03971 H506Q Disease Disease P03971 V12G Disease Neutral P03971 Q185E Neutral Neutral P03971 I49S Neutral Neutral P03971 V477A Disease Neutral P03971 L70P Disease Disease P03971 R194C Disease Neutral P03971 Q325R Neutral Neutral P03971 R123W Disease Neutral P03971 G101V Disease Disease P03971 C525Y Disease Disease P03971 Y167C Disease Disease Q8IZ02 L241I Neutral Neutral Q6NYC8 P356L Neutral Neutral Q4ZG55 D1687N Neutral Neutral Q4ZG55 V122A Neutral Neutral Q4ZG55 R973Q Neutral Neutral Q4ZG55 L1814V Neutral Neutral Q4ZG55 N77T Neutral Neutral Q4ZG55 Y1463C Neutral Disease Q4ZG55 V346M Neutral Neutral Q9Y251 N260S Disease Neutral Q8WWQ2 Y579F Neutral Neutral Q8WWQ2 A315T Neutral Neutral Q0JRZ9 M371V Neutral Neutral Q32P28 G349R Neutral Disease Q32P28 P506R Neutral Disease Q32P28 M549I Neutral Neutral Q9UKK9 I123T Neutral Neutral Q8N944 P340S Neutral Neutral Q9UM07 A82V Neutral Neutral Q9UM07 A112G Neutral Neutral Q9UM07 S275F Neutral Neutral Q9UM07 R131T Neutral Neutral Q9UM07 P102T Neutral Neutral Q9UM07 D89N Neutral Disease Q9UM07 S55G Neutral Neutral Q9UM07 M164T Neutral Neutral Q8IZF7 I467V Neutral Neutral Q8IZF7 Q148R Neutral Neutral P50053 A43T Disease Disease P50053 R159G Neutral Neutral P50053 G40R Disease Disease P50053 V49I Neutral Neutral Q96NY8 F53L Neutral Neutral Q5T5C0 N436S Neutral Neutral P20783 G76E Neutral Neutral Q8IX19 I167V Neutral Neutral Q8NH09 V48M Neutral Neutral P06127 R461H Neutral Neutral P06127 P224L Neutral Neutral P57075 Q286R Neutral Neutral P57075 L28F Neutral Neutral P57075 S18G Neutral Neutral Q96NB3 I16V Neutral Neutral Q96NB3 F135L Neutral Neutral Q96NB3 S93P Neutral Neutral Q96NB3 S154T Neutral Neutral Q96NB3 Q99H Neutral Neutral O43819 R171W Disease Disease O43819 S225F Disease Disease O43819 R20P Neutral Neutral O43819 E140K Disease Neutral Q8N614 M212T Neutral Neutral Q8N614 Y48C Neutral Disease Q9NR83 E233D Neutral Neutral P12955 L435F Neutral Neutral P12955 G278D Disease Disease P12955 R184Q Disease Disease P12955 D276N Disease Disease P12955 G448R Disease Disease O60303 V1597I Neutral Neutral O60303 R885Q Neutral Neutral O60303 R1368Q Neutral Neutral O60303 A535S Neutral Neutral O60303 T1267A Neutral Neutral O60303 T522M Neutral Neutral Q9N2K0 V81L Neutral Neutral Q9N2K0 F150L Neutral Neutral Q9NSC7 V80A Neutral Neutral Q9NZU0 H400Q Neutral Neutral Q5TC84 S47P Neutral Neutral Q9C0B2 G628C Neutral Disease Q9C0B2 S50I Neutral Neutral Q9C0B2 I363V Neutral Neutral P05090 T178K Neutral Neutral P05090 S115L Neutral Disease P05090 F15S Neutral Neutral P41273 P17A Neutral Neutral O14832 P173S Disease Neutral O14832 E197Q Disease Disease O14832 R245Q Disease Neutral O14832 D177G Disease Disease O14832 F257S Disease Disease O14832 Q176K Disease Disease O14832 P29S Disease Neutral O14832 N83Y Disease Neutral O14832 I199F Disease Disease O14832 N269H Disease Disease O14832 R275Q Disease Disease O14832 W193R Disease Disease O14832 R275W Disease Disease O14832 H220Y Disease Disease O14832 H175R Disease Disease O14832 G204S Disease Disease Q96G46 R185G Neutral Neutral Q96G46 D609N Neutral Neutral Q12791 D434G Disease Neutral O75489 P249Q Neutral Neutral O60663 C60F Disease Disease O60663 C95Y Disease Disease O60663 C95F Disease Disease O60663 C60Y Disease Disease O60663 C123Y Disease Disease O60663 R226P Disease Disease O60663 S218P Disease Disease O60663 C60W Disease Disease O60663 N246K Disease Disease O60663 C57R Disease Disease O60663 C123F Disease Disease O60663 A213P Disease Disease O60663 C63R Disease Disease O60663 D83G Disease Disease O60663 H54Y Disease Disease O60663 W243C Disease Disease O60663 H54N Disease Disease O60663 R200Q Disease Disease O60663 H114Y Disease Disease O60663 C120S Disease Disease O60663 H54Q Disease Disease O60663 C36R Disease Disease O60663 C60G Disease Disease O60663 C80W Disease Disease O60663 L58W Disease Disease O60663 C117Y Disease Disease O60663 C142W Disease Disease O60663 C36S Disease Disease O60663 A230V Disease Disease O60663 L229P Disease Disease Q9BQP7 S15C Neutral Neutral P11150 T405M Disease Neutral Q9Y5X9 R312H Neutral Neutral Q17RR3 F450Y Neutral Disease P11150 S440N Neutral Neutral Q9Y5X9 G96S Neutral Disease P11150 V342I Neutral Neutral P11150 N215S Neutral Neutral P11150 S289F Disease Disease Q9Y5X9 T111I Neutral Neutral P11150 D409A Neutral Disease Q17RR3 L2F Neutral Neutral P11150 L356F Neutral Neutral P11150 V95M Neutral Disease Q17RR3 F332L Neutral Neutral Q9Y5X9 G26S Neutral Neutral Q68D06 N4S Neutral Neutral Q68D06 A50T Neutral Neutral Q7Z7L1 D301N Neutral Neutral Q68D06 E652K Neutral Neutral Q7Z7L1 V121F Neutral Neutral Q08AF3 P787L Neutral Disease Q08AF3 A797V Neutral Neutral Q7Z7L1 Y822C Neutral Disease Q8TEC5 V687I Neutral Neutral Q8TEC5 R592W Neutral Neutral Q8TEC5 C267R Neutral Neutral Q8TEC5 A710G Neutral Neutral Q71RS6 T111A Neutral Neutral Q9NQ38 K420E Neutral Neutral Q9BXY0 Q277R Neutral Neutral Q96AY2 I350T Neutral Neutral Q96AY2 I49V Neutral Neutral Q96AY2 E69D Neutral Neutral Q5VWP3 I159V Neutral Neutral Q5VWP3 T320S Neutral Neutral Q5VWP3 R6H Neutral Neutral Q3ZCQ3 S114L Neutral Disease O43516 A495G Neutral Neutral Q9H4L7 R140C Neutral Neutral Q9H4L7 S247N Neutral Neutral Q9H4L7 S245Y Neutral Neutral Q9H4L7 S66F Neutral Neutral Q9H4L7 P351Q Neutral Neutral Q9H4L7 L135F Neutral Neutral Q9H4L7 A301V Neutral Neutral Q9H4L7 V972A Neutral Disease O75128 A1015P Neutral Neutral O75128 D577A Neutral Neutral O75128 D927N Neutral Neutral O75128 V607I Neutral Neutral P61278 A11V Neutral Neutral P61278 N61T Neutral Neutral Q9HC21 G177A Disease Disease Q8TEQ6 Q682R Neutral Neutral Q13049 D487N Disease Disease Q13049 T257R Neutral Neutral Q13049 P130S Disease Neutral Q13049 R408C Neutral Disease Q99707 H920D Disease Disease Q99707 R61K Neutral Neutral Q99707 P1173L Disease Neutral Q99707 C255Y Neutral Disease Q99707 D919G Neutral Neutral Q9Y2L1 T326R Neutral Neutral Q9Y2L1 N269S Neutral Neutral Q8TF46 N747S Neutral Neutral Q8TF46 I518V Neutral Neutral Q8TF46 D614G Neutral Disease Q8N6I1 A6T Neutral Neutral P00568 R128W Disease Disease P00568 E123Q Neutral Disease Q8N0S6 I117F Neutral Neutral Q14541 M190I Neutral Disease P41235 R136W Disease Neutral P41235 T139I Neutral Neutral P41235 E285Q Disease Disease P41235 P445S Neutral Neutral P41235 V402I Disease Neutral Q5T619 N111K Neutral Neutral O75487 E391D Neutral Neutral Q9Y625 V412M Neutral Neutral O75487 A442V Neutral Neutral Q8IY34 F349I Neutral Disease Q8IVF5 R1101C Neutral Disease Q8IVF5 D1572E Neutral Neutral Q6ZQY2 R77C Neutral Disease Q6ZQY2 G3R Neutral Neutral Q96JN2 D218H Neutral Neutral Q96JN2 E1049Q Neutral Neutral Q96LX7 P321L Neutral Neutral Q96LX7 I525V Neutral Neutral Q6IAA8 S73L Neutral Neutral Q9NVL8 Y235C Neutral Neutral P03891 Q63R Neutral Disease P03891 F325L Neutral Neutral P03891 I57T Neutral Neutral P03891 V43I Neutral Neutral P03891 I69V Neutral Neutral P03891 N150D Disease Neutral P03891 P42L Neutral Disease P03891 G259S Disease Disease P03891 T185A Neutral Neutral P03891 N150S Neutral Neutral P03891 A331S Disease Neutral P03891 A265V Neutral Disease P03891 A265T Neutral Neutral P03891 S148P Neutral Neutral P03891 I278T Neutral Neutral P03891 L237M Neutral Neutral P03891 A331T Neutral Neutral P03891 T119A Neutral Neutral P03891 N88S Neutral Neutral P03891 I159T Neutral Neutral P03891 T333A Neutral Neutral P02766 A65D Disease Neutral P02766 T79K Disease Neutral P02766 I93V Disease Neutral P02766 G73E Disease Disease P02766 I88L Disease Neutral P02766 E62G Disease Neutral P02766 R124H Neutral Neutral P02766 R124C Neutral Neutral P02766 E62D Disease Neutral P02766 S72P Disease Neutral P02766 Y98F Disease Neutral P02766 L78R Disease Disease P02766 K90N Disease Neutral P02766 A65S Disease Neutral P02766 L78H Disease Disease P02766 V50G Disease Disease P02766 F53L Disease Neutral P02766 N144S Disease Neutral P02766 P44S Disease Disease P02766 V50L Disease Neutral P02766 G26S Neutral Neutral P02766 C30R Disease Disease P02766 D38G Disease Disease P02766 E74G Disease Neutral P02766 E74K Disease Neutral P02766 S97Y Disease Disease P02766 I127M Disease Neutral P02766 S70I Disease Neutral P02766 I104T Disease Neutral P02766 A117G Disease Neutral P02766 V142I Disease Neutral P02766 S70R Disease Neutral P02766 F84L Disease Disease P02766 V48M Disease Neutral P02766 G67V Disease Neutral P02766 G121S Neutral Disease P02766 A117S Disease Disease P02766 L32P Disease Disease P02766 K55N Disease Neutral P02766 V40I Disease Neutral P02766 W61L Disease Disease P02766 E81G Disease Neutral P02766 T69I Disease Disease P02766 G67A Disease Neutral P02766 D58A Disease Neutral P02766 L75P Disease Neutral P02766 L75Q Disease Neutral P02766 T80A Disease Neutral P02766 A65T Disease Neutral P02766 G67E Disease Neutral P02766 R54T Disease Neutral P02766 I127V Disease Neutral P02766 E81K Disease Neutral P02766 A140S Disease Neutral P02766 S43N Disease Neutral P02766 Y134H Disease Disease P02766 Y136S Disease Disease P02766 F53I Disease Neutral P02766 V142A Disease Neutral P02766 A56P Disease Disease P02766 I104N Disease Disease P02766 D58V Disease Disease P02766 T69A Disease Disease P02766 F64S Disease Neutral P02766 D38E Disease Disease P02766 M33I Neutral Neutral P02766 E109Q Disease Neutral P02766 G67R Disease Neutral P02766 V50M Disease Neutral P02766 I104S Disease Neutral P02766 Y134C Disease Disease P02766 H110N Neutral Neutral P02766 F53V Disease Neutral P02766 D94H Neutral Disease P02766 V50A Disease Neutral P02766 E109K Disease Disease P02766 A111S Disease Neutral P02766 P122R Neutral Neutral P02766 V91A Disease Neutral P02766 L131M Disease Neutral P02766 Y89H Disease Disease P02766 T126N Disease Disease Q92831 N386S Neutral Neutral Q9BZG8 S389R Disease Neutral Q9BZG8 A7V Disease Neutral Q9BZG8 L335V Disease Neutral Q9BZG8 A34D Disease Disease P07202 R665W Disease Disease P07202 S398T Neutral Disease P07202 E378K Disease Neutral P07202 Q660E Disease Disease P07202 G771R Disease Disease P07202 D796Y Disease Disease P07202 G533C Disease Disease P07202 R693W Disease Disease P07202 A257S Neutral Neutral P07202 G493S Disease Disease P07202 V839I Disease Neutral P07202 Y453D Disease Disease P07202 A53P Disease Disease P07202 L458P Disease Disease P07202 G590S Disease Neutral P07202 A326T Disease Disease P07202 R648Q Disease Disease P07202 V847A Neutral Neutral P07202 C808R Disease Disease P07202 M706V Neutral Neutral P07202 L793P Neutral Neutral P07202 T725P Neutral Neutral P07202 V433M Disease Disease P07202 R846W Neutral Neutral P07202 E799K Disease Neutral P07202 N307T Disease Neutral P07202 P499L Disease Disease P07202 R491H Disease Disease P07202 I447F Disease Disease P07202 W527C Disease Disease P07202 V618M Neutral Neutral P07202 D240N Disease Disease P07202 A373S Neutral Neutral Q9HC62 T301K Neutral Neutral P27448 V452A Neutral Neutral P43026 C400Y Disease Disease P43026 S276A Neutral Neutral P43026 M173V Disease Disease P43026 R438L Disease Neutral P43026 E491K Disease Disease P43026 R163G Neutral Neutral P43026 L441P Disease Disease P43026 H440L Disease Neutral P43026 S439T Disease Neutral P43026 S475N Disease Disease O00507 P1035S Neutral Neutral O00507 T1060A Neutral Neutral Q9Y4F9 E424K Neutral Neutral Q9Y4F9 E495K Neutral Neutral Q9Y4F9 S452C Neutral Neutral Q9Y4F9 V320M Neutral Neutral Q9Y4F9 R520C Neutral Neutral Q9Y4F9 A145G Neutral Neutral Q16518 Y144D Disease Disease Q16518 R44Q Disease Disease Q16518 A132T Disease Neutral Q16518 E417Q Disease Disease Q16518 N321K Disease Neutral Q16518 H68Y Disease Disease Q16518 R515W Disease Disease Q16518 R91W Disease Neutral Q16518 L341S Disease Disease Q16518 R91Q Disease Neutral Q16518 P363T Disease Neutral Q16518 A393G Disease Disease Q16518 A434V Neutral Neutral Q16518 V452G Disease Disease Q16518 L22P Disease Disease Q16518 V287F Disease Disease Q16518 H182Y Disease Disease Q16518 G40S Disease Disease Q16518 Y368H Disease Disease Q16518 Y431C Disease Disease Q14003 F448L Disease Neutral Q14003 R420H Disease Disease Q6P6B1 Q244P Neutral Neutral Q6P6B1 H287R Neutral Neutral Q6P6B1 R59H Neutral Neutral Q86UA6 K103N Neutral Neutral Q96QS3 R332P Disease Disease Q96QS3 A521T Disease Neutral Q96QS3 L343Q Disease Disease Q96QS3 P353L Disease Disease Q96QS3 R332H Disease Disease Q96QS3 P353R Disease Disease Q96QS3 G286S Disease Neutral Q96QS3 L33P Disease Disease Q96QS3 T333N Disease Disease O95969 P53L Neutral Neutral O95969 V80A Neutral Neutral Q9H987 P707L Neutral Neutral Q9BWW9 T272M Neutral Neutral Q9BWW9 S406C Neutral Neutral Q9BWW9 T323M Neutral Neutral Q5TBC7 D90N Neutral Neutral O15431 P25A Neutral Neutral P41091 K125R Neutral Neutral P17677 V59I Neutral Neutral Q9Y4D7 M870V Neutral Neutral Q6NT16 V204I Neutral Neutral Q8IWX8 N199H Neutral Neutral P11413 R198P Disease Disease P11413 N126D Neutral Neutral P11413 R439P Disease Disease P11413 R387C Disease Disease P11413 G410D Disease Disease P11413 V394L Disease Neutral P11413 V68M Neutral Disease Q86SX6 A146T Neutral Neutral Q13562 R111L Disease Disease Q13562 A45T Neutral Neutral Q13562 P197H Neutral Neutral Q9HD90 K68T Neutral Neutral P08887 D358A Neutral Neutral O95947 S178F Neutral Disease O95947 P179S Neutral Disease P57082 G6A Neutral Neutral Q99593 R237W Disease Disease Q99593 Q49K Disease Neutral P57082 Q531R Disease Neutral Q99593 R237Q Disease Disease P57082 A314V Neutral Neutral Q99593 G80R Disease Disease P57082 A35V Neutral Neutral Q99593 I54T Disease Neutral P57082 G248V Disease Disease A5PLN7 H505R Neutral Neutral A5PLN7 L748V Neutral Neutral A5PLN7 K332E Neutral Neutral A5PLN7 R722W Neutral Neutral A5PLN7 K437E Neutral Neutral A5PLN7 P532L Neutral Neutral O95567 C46R Neutral Disease O95567 T210R Neutral Neutral Q96L16 N52S Neutral Neutral Q2M329 E96K Neutral Neutral Q15022 N216I Neutral Neutral Q01453 G150C Disease Disease Q01453 V65F Disease Disease Q01453 T118M Disease Disease Q01453 L147R Disease Disease Q01453 L16P Disease Disease Q01453 S22F Disease Disease Q01453 S149R Disease Disease Q01453 G100R Disease Disease Q01453 C109R Disease Disease Q01453 G150D Disease Disease Q01453 D37V Disease Disease Q01453 R157G Neutral Disease Q01453 H12Q Disease Disease Q01453 R157W Disease Disease Q01453 A67T Disease Disease Q01453 S79C Disease Disease Q01453 A67P Disease Disease Q01453 S72P Disease Disease Q01453 L80P Disease Disease Q01453 L105R Disease Disease Q01453 W28R Disease Disease Q01453 L19P Disease Disease Q01453 G107V Disease Disease Q01453 S79P Disease Disease Q01453 S76I Disease Disease Q01453 S72W Disease Disease Q01453 M69K Disease Disease Q01453 S72L Disease Disease Q01453 L80R Disease Disease Q01453 T23R Disease Disease Q01453 G93R Disease Disease Q01453 G100E Disease Disease Q01453 I137V Neutral Neutral Q01453 L71P Disease Disease Q01453 V30M Disease Disease O75683 R163W Neutral Neutral O75683 T311M Neutral Neutral O75683 T175M Neutral Neutral P54687 E321K Neutral Disease P09848 G1363S Disease Disease P09848 V362I Neutral Neutral P09848 N1639S Neutral Disease P09848 Q268H Disease Neutral P09848 V219I Neutral Neutral Q86Y91 Q518R Neutral Neutral Q9UBC1 C224R Neutral Neutral P02786 G142S Neutral Neutral P07550 I159L Neutral Neutral P07550 T164I Neutral Neutral P07550 K375R Neutral Neutral P07550 I159F Neutral Neutral P07550 Q27E Neutral Neutral P07550 V34M Neutral Disease P07550 S220C Neutral Neutral P07550 R16G Neutral Neutral Q03164 A53V Neutral Neutral Q03164 S2319T Neutral Neutral Q03164 Q2387R Neutral Neutral Q03164 A30G Neutral Neutral Q03164 P2354R Neutral Neutral Q03164 E502K Neutral Neutral Q03164 V3714I Neutral Neutral Q03164 S3773A Neutral Neutral P30048 A218T Neutral Disease P30048 S55R Neutral Neutral P30048 T234I Neutral Disease Q8NBF2 V314I Neutral Neutral Q4LDR2 E17V Neutral Neutral Q96K30 T220K Neutral Neutral Q6P4I2 R249H Neutral Neutral Q12923 Y2081D Neutral Neutral Q12923 L1419P Neutral Disease Q12923 I1522M Neutral Neutral Q12923 E1625K Neutral Neutral P52333 R582W Disease Disease O60674 A377E Neutral Disease P52333 V722I Disease Neutral O60674 G127D Neutral Disease P52333 E481G Disease Disease O60674 R1063H Neutral Neutral P52333 Y100C Disease Disease O60674 V617F Disease Disease P52333 C759R Disease Disease P52333 P151R Disease Neutral P52333 D169E Disease Neutral P52333 G589S Disease Disease O60674 K607N Disease Disease O60674 L393V Neutral Neutral O60674 K346R Neutral Neutral P52333 L910S Disease Disease P23458 N961K Neutral Neutral Q07837 T341A Disease Neutral Q07837 M467K Disease Disease Q07837 P128Q Disease Disease Q07837 R181Q Disease Neutral Q07837 E268K Disease Disease Q07837 T216M Disease Disease Q07837 E482K Disease Disease Q07837 R584T Disease Disease Q07837 F599S Disease Disease Q07837 P508A Disease Disease Q07837 G398R Disease Disease Q07837 R365W Disease Disease Q07837 P615T Disease Disease Q07837 L678P Disease Disease Q07837 R362C Disease Disease Q07837 G481V Disease Disease Q07837 Y582H Disease Disease Q07837 M467T Disease Disease Q07837 T652R Disease Neutral Q07837 M618I Neutral Neutral Q07837 R452W Disease Disease Q07837 Y151C Disease Disease Q07837 N253K Disease Disease Q07837 G600E Disease Disease Q07837 F648S Disease Neutral Q07837 Y461H Disease Neutral Q07837 Q510R Disease Disease Q07837 R362H Disease Disease Q17R89 V463M Neutral Neutral Q8N9V3 R320S Neutral Neutral Q8N9V3 H223D Neutral Neutral Q8N9V3 K215T Neutral Neutral Q8N9V6 L153I Neutral Disease Q9NR50 R225Q Disease Neutral Q9NR50 A87V Disease Disease P15924 I305F Neutral Disease P15924 Y1512C Neutral Neutral P15924 R1255K Disease Neutral P15924 S299R Disease Disease P15924 R1775I Disease Neutral P15924 N287K Disease Disease P15924 R1738Q Neutral Disease P15924 R2366C Disease Disease Q9GZT5 P302T Neutral Neutral Q99436 V39A Neutral Neutral P78380 K167N Neutral Neutral P05452 A55S Neutral Neutral P05452 V58M Neutral Neutral O75596 Q197K Neutral Neutral P05452 S106G Neutral Neutral P18031 G381S Neutral Neutral P18031 P387L Neutral Neutral P19320 G413A Neutral Neutral P19320 I716L Neutral Neutral P19320 S318F Neutral Disease P19320 T384A Neutral Neutral Q9BXT8 K346N Neutral Neutral Q9BXT8 S501G Neutral Neutral Q9BXT8 G467S Neutral Neutral Q709C8 S2913N Neutral Neutral Q709C8 R974K Neutral Neutral Q709C8 Y1302C Neutral Disease Q709C8 I1495V Neutral Neutral Q709C8 T1485A Neutral Neutral Q709C8 V2322M Neutral Neutral Q709C8 R153H Neutral Neutral Q709C8 I1132V Neutral Neutral Q709C8 S1592Y Neutral Neutral Q96M53 Q237R Neutral Neutral Q96HP8 T122A Neutral Neutral Q96HP8 L187F Neutral Neutral Q96HP8 T208A Neutral Neutral Q86UK5 R950W Disease Neutral Q86UK5 I283R Disease Disease Q8IZ57 I41V Neutral Neutral Q9Y283 P482R Disease Neutral Q9Y283 L493S Disease Disease Q6UWL2 H524Q Neutral Neutral Q8ND61 G42D Neutral Disease Q8ND61 A176T Neutral Neutral Q8ND61 S230Y Neutral Neutral Q8ND61 D65N Neutral Neutral Q8ND61 I407V Neutral Neutral Q8ND61 L422V Neutral Neutral Q8ND61 A298T Neutral Neutral P53004 A3T Neutral Neutral P53004 Q56R Neutral Neutral P53004 L37V Neutral Neutral P14151 F193L Neutral Neutral P14151 N369D Neutral Neutral P14151 E201Q Neutral Neutral P14151 P213S Neutral Neutral P60368 N15D Neutral Neutral P60331 P39L Neutral Disease P60368 A117P Neutral Neutral P60368 P107T Neutral Disease P60411 C182Y Neutral Disease P60014 T72P Neutral Neutral P60368 R241G Neutral Disease P60412 Y213S Neutral Neutral P60370 V235L Neutral Disease P60370 D20N Neutral Disease P60370 P268R Neutral Neutral Q96EN8 S120N Neutral Neutral Q96EN8 V541L Neutral Neutral Q96EN8 H703N Neutral Neutral Q96EN8 M358V Neutral Neutral Q96EN8 G184S Neutral Neutral Q96EN8 A57P Disease Disease Q96EN8 I170T Neutral Disease Q96EN8 R225H Neutral Neutral Q96EN8 T294I Disease Disease Q96EN8 V867A Neutral Neutral Q96EN8 D495N Neutral Neutral P51460 A60T Neutral Neutral P51460 N110K Disease Disease P51460 R102H Neutral Neutral P51460 V43L Neutral Disease P51460 R102C Disease Neutral P51460 P49S Neutral Neutral P51460 A24G Neutral Neutral P51460 P93L Disease Neutral Q08999 Y210C Neutral Neutral Q8TDI8 M654V Disease Neutral Q8TDI8 D572N Disease Disease P35498 Y426N Disease Disease P35498 N985I Disease Disease P35498 R1648H Disease Disease Q15858 L869H Disease Disease Q15858 V1309F Disease Disease P35498 T875M Disease Neutral P35498 T112I Disease Disease P35498 E1881D Disease Neutral P35498 A1685V Disease Disease P35498 T1909I Disease Disease P35498 L986F Disease Disease P35498 R393H Disease Disease P35498 W1812G Disease Disease Q99250 R188W Disease Disease Q99250 R1319Q Disease Disease Q99250 R19K Neutral Neutral P35498 G177E Disease Disease P35498 T297I Disease Neutral P35498 F1463S Disease Neutral P35498 K1270T Disease Disease Q15858 T1475I Disease Disease P35498 W1434R Disease Disease Q99250 R524Q Neutral Neutral P35498 M960V Disease Disease P35498 S1231R Disease Disease P35498 M1852T Disease Disease P35498 D188V Disease Disease P35498 I252N Disease Disease P35498 N1011I Disease Disease P35498 I1656M Disease Disease P35498 F1808L Disease Disease Q99250 L1330F Disease Disease P35498 W1204R Disease Disease P35498 S1362P Disease Disease Q99250 F385Y Neutral Neutral P35498 S103G Disease Disease P35498 V1390M Disease Neutral Q15858 I1472T Disease Neutral Q15858 V1309D Disease Disease Q9NY46 V1107A Neutral Neutral Q15858 S241T Disease Neutral P35498 F1831S Disease Disease P35498 V1428A Disease Disease P35498 P1632S Disease Disease P35498 C959R Disease Disease P35498 G979R Disease Disease P35498 R946C Disease Neutral P35498 P1668A Disease Neutral Q99250 L1563V Disease Disease P35498 V983A Disease Disease P35498 I227S Disease Disease Q15858 F1473V Disease Disease Q99250 R223Q Disease Disease Q15858 I859T Disease Disease P35498 F1692S Disease Disease P35498 R1657C Disease Disease P35498 R931C Disease Disease Q15858 M1638K Disease Disease P35498 Y790C Disease Disease P35498 A1685D Disease Disease P35498 T808S Disease Disease Q99250 V892I Disease Neutral P35498 G265W Disease Disease Q15858 M932L Neutral Disease Q15858 R1007C Disease Disease Q15858 V1310F Disease Disease P35498 F902C Disease Disease P35498 Y1781C Disease Disease Q15858 F1460V Disease Disease P35498 Y1684C Disease Disease P35498 Q1450R Disease Disease P35498 V1611F Disease Disease P35498 W280R Disease Neutral P35498 H939Q Disease Neutral P35498 A1067T Neutral Neutral P35498 E78D Disease Neutral Q15858 D1919G Neutral Disease P35498 G1674R Disease Disease Q9NY46 L1813S Neutral Disease P35498 M1780T Disease Disease P35498 G1749E Disease Disease Q99250 L1003I Disease Neutral Q15858 R1161W Neutral Disease P35498 F1263L Disease Disease P35498 T1709I Disease Disease P35498 M145T Disease Neutral P35498 F1661S Disease Neutral P35498 V944A Disease Disease P35498 V1353L Disease Neutral P35498 W190R Disease Disease P35498 G1233R Disease Disease P35498 L1461I Disease Neutral P35498 L1265P Disease Disease Q9NY46 S606T Neutral Neutral P35498 R101Q Disease Disease P35498 R946H Disease Neutral P35498 Q1489K Disease Disease P35498 M934I Disease Disease P35498 G343E Disease Disease P35498 R1648C Disease Disease P35498 L1355P Disease Neutral Q9BSJ8 R764C Neutral Disease P54886 R84Q Disease Neutral Q99457 P224A Neutral Neutral Q6N021 M218V Neutral Neutral Q6N021 P29R Neutral Neutral Q6N021 P363L Neutral Neutral Q6N021 A912G Neutral Neutral Q6ZN57 R142G Neutral Neutral Q6ZN57 Q113H Neutral Neutral Q9NQZ8 V105I Neutral Neutral Q9BZW5 P59S Neutral Neutral Q9BZW5 I17T Neutral Disease Q9Y6U7 A322T Neutral Neutral Q6P1Q0 V84I Neutral Neutral P78363 E1087K Disease Disease P78363 A407V Disease Neutral O95477 N1800H Disease Neutral P78363 L1525P Disease Disease P78363 R220C Disease Neutral P78363 V77E Disease Disease P78363 R1108H Disease Disease P78363 E2096K Disease Disease P78363 C1488Y Disease Disease P78363 R2030Q Disease Disease P78363 P68R Disease Disease P78363 R1820P Disease Disease P78363 R1300Q Disease Neutral P78363 S765N Disease Neutral P78363 G550R Disease Disease P78363 R1443H Disease Neutral P78363 P1380L Disease Disease P78363 G863A Disease Disease P78363 S206R Disease Neutral P78363 R1129L Disease Disease P78363 A854T Disease Neutral P78363 L2035P Disease Disease O95477 R230C Disease Neutral P78363 H2128R Disease Disease P78363 R572P Disease Disease P78363 S1696N Disease Neutral P78363 W339G Disease Disease P78363 S336C Disease Disease P78363 C75G Disease Disease P78363 R1517S Disease Neutral P78363 L2060R Disease Disease P78363 E1036K Disease Neutral P78363 T716M Disease Neutral P78363 L1940P Disease Disease O95477 C1477R Disease Disease P78363 N1805D Disease Neutral P78363 R653C Disease Neutral P78363 W821R Disease Disease P78363 T971N Disease Disease P78363 E1885K Disease Disease O95477 D1099Y Disease Disease P78363 Q957R Disease Disease P78363 H1406Y Disease Neutral P78363 V1896D Disease Disease P78363 A60V Disease Neutral P78363 R572Q Disease Disease O95477 R1680W Disease Disease P78363 V1693I Disease Neutral P78363 T1019M Disease Neutral P78363 T1428M Disease Neutral P78363 K1031E Disease Neutral P78363 R1705L Disease Disease P78363 N96D Disease Disease P78363 R1640W Disease Disease P78363 G1439D Disease Disease P78363 S445R Disease Disease P78363 N965S Disease Disease P78363 C1490Y Disease Disease P78363 G1977S Disease Disease O95477 M1091T Disease Disease P78363 L2027F Disease Disease P78363 A1794D Disease Disease P78363 V935A Disease Neutral P78363 G607W Disease Disease P78363 W1408R Disease Neutral P78363 A1598D Disease Neutral P78363 L541P Disease Disease P78363 A60T Disease Neutral P78363 G1508C Disease Disease P78363 V849A Disease Disease P78363 L1631P Disease Disease P78363 R333W Disease Disease P78363 R2107H Disease Disease P78363 Y340D Disease Disease P78363 C54Y Disease Disease P78363 L244P Disease Disease P78363 R943W Disease Disease P78363 F525C Disease Disease P78363 N96H Disease Disease P78363 T1253M Disease Neutral P78363 V1433I Disease Neutral P78363 C2150Y Disease Disease O95477 A1046D Disease Disease O95477 S1506L Disease Disease P78363 L1250P Disease Disease P78363 C230S Disease Disease P78363 T897I Disease Neutral P78363 G978C Disease Disease P78363 D249G Disease Disease P78363 V767D Disease Disease P78363 T1019A Disease Neutral P78363 A1038V Disease Neutral O95477 Q597R Disease Disease O95477 P85L Disease Neutral P78363 R1108L Disease Disease P78363 V1884E Disease Disease P78363 R24H Disease Neutral P78363 E1022K Disease Disease P78363 M1733T Disease Disease P78363 C1488R Disease Disease P78363 Q1513R Disease Neutral P78363 T1526M Disease Disease P78363 F608I Disease Disease P78363 E1399K Disease Neutral O95477 I1517R Disease Disease P78363 V2050L Disease Neutral P78363 S1071L Disease Disease P78363 G851D Disease Disease P78363 Y2071F Disease Disease P78363 R2139W Disease Disease P78363 G1961E Disease Neutral P78363 P1776L Disease Disease P78363 F1440V Disease Disease P78363 G1091E Disease Disease P78363 K2160R Disease Neutral P78363 A60E Disease Disease P78363 C1488F Disease Disease P78363 E1087D Disease Disease P78363 G991R Disease Disease P78363 I824T Disease Neutral P78363 R1129C Disease Disease P78363 F1440S Disease Disease P78363 Q635K Disease Neutral P78363 R2038W Disease Disease P78363 F873L Disease Disease P78363 S1689P Disease Disease P78363 R2263L Disease Disease P78363 R1898H Disease Neutral P78363 N58K Disease Disease P78363 H1838Y Disease Neutral P78363 N247S Disease Disease P78363 S1736P Disease Disease P78363 C764Y Disease Disease P78363 L11P Disease Disease P78363 R1640Q Disease Disease P78363 L1430P Disease Disease P78363 A192T Disease Neutral P78363 I1562T Disease Neutral O95477 W590S Disease Neutral P78363 P309R Disease Neutral P78363 E2131K Disease Disease P78363 L1014R Disease Disease P78363 V1072A Disease Neutral P78363 R2106C Disease Disease P78363 L1388P Disease Disease P78363 T1537M Disease Disease P78363 S765R Disease Disease P78363 G1748R Disease Disease O95477 P2150L Disease Neutral P78363 G1975R Disease Disease P78363 S974P Disease Disease P78363 A549P Disease Disease P78363 C2150R Disease Disease P78363 G65E Disease Disease P78363 N380K Disease Neutral O95477 D1289N Disease Neutral P78363 D645N Disease Disease P78363 R2149L Disease Disease P78363 T300N Disease Neutral P78363 G2146D Disease Disease P78363 R1108C Disease Disease P78363 R18W Disease Disease P78363 D1532N Disease Neutral P78363 G607R Disease Disease P78363 D523E Disease Neutral P78363 P68L Disease Disease P78363 L1970F Disease Disease P78363 Q190H Disease Neutral P78363 E471K Disease Neutral P78363 T972N Disease Disease P78363 W1408L Disease Disease P78363 G818E Disease Disease P78363 R1097C Disease Disease P78363 R602W Disease Disease P78363 L1971R Disease Disease P78363 S100P Disease Disease P78363 R2077W Disease Disease P78363 Q1703K Disease Neutral P78363 S1063P Disease Disease P78363 V643M Disease Neutral P78363 R537C Disease Neutral P78363 L686S Disease Disease P78363 V931M Disease Disease O95477 F2009S Disease Neutral P78363 R1843W Disease Disease O95477 A255T Disease Neutral P78363 R602Q Disease Neutral P78363 L1201R Disease Disease P78363 N1799D Disease Disease P78363 G1578R Disease Neutral P78363 T959I Disease Neutral P78363 T1112N Disease Disease P78363 V989A Disease Neutral P78363 D1204N Disease Neutral P78363 G72R Disease Disease P78363 P1486L Disease Disease O95477 R587W Disease Disease P78363 E1122K Disease Disease P78363 R2107C Disease Disease P78363 G1886E Disease Disease P78363 R2077G Disease Disease P78363 I156V Disease Neutral P78363 Q636H Disease Neutral P78363 P1780A Disease Neutral P78363 V1429A Disease Neutral O95477 N935S Disease Disease O95477 N935H Disease Disease P78363 E328V Disease Disease P78363 R212C Disease Neutral P78363 R1055W Disease Disease P78363 Y1652D Disease Neutral O95477 T929I Disease Neutral P78363 L797P Disease Disease P78363 L1729P Disease Disease O95477 R2081W Disease Disease O95477 A937V Disease Disease P78363 L2229P Disease Disease P78363 L2241V Disease Disease P78363 L1763P Disease Disease O95180 E1974G Neutral Neutral P55769 T19N Neutral Neutral O00192 R909W Neutral Neutral O60716 Y217C Neutral Disease O00192 R912W Neutral Neutral O60716 R915K Neutral Neutral O00192 R909Q Neutral Neutral O00192 R906Q Neutral Neutral O00192 P220L Neutral Neutral O00192 V175A Neutral Neutral O60716 S171F Neutral Neutral O60716 R464C Neutral Neutral O95425 A189V Neutral Neutral O95425 A1235P Neutral Neutral O95425 S1688P Neutral Disease Q9NY56 N61K Neutral Neutral Q4AE62 M137I Neutral Neutral Q96T23 S465P Neutral Neutral P02654 T71S Neutral Neutral P02654 I16M Neutral Neutral Q6ZU65 P1308A Neutral Neutral P43119 V25M Neutral Neutral O95394 D466N Neutral Neutral Q8NFF2 V596I Neutral Neutral Q6PIJ6 S592P Neutral Neutral Q9NWL6 M434T Neutral Neutral Q9NWL6 R190G Neutral Neutral Q6X4W1 T480A Disease Neutral Q15796 R133C Disease Disease Q15796 L440R Disease Disease Q15796 D450E Disease Disease Q15796 P445H Disease Disease Q8NDX9 R176C Neutral Disease Q8NDX9 D102N Neutral Neutral Q8NDX9 S131Y Neutral Neutral P50542 S600W Disease Disease P50542 N526K Disease Disease P21589 T376A Neutral Neutral P82279 C587Y Disease Disease P82279 I989T Disease Disease P82279 G1205R Disease Neutral P82279 T745M Disease Disease P82279 C1181R Disease Neutral P82279 N894S Disease Neutral P82279 C480G Disease Disease P82279 C383Y Disease Disease P82279 I205T Neutral Neutral P82279 A1354T Disease Neutral P82279 T289M Neutral Neutral P82279 M1041T Disease Neutral P82279 E710Q Disease Disease P82279 C480R Disease Disease P82279 Y433C Disease Disease P82279 C891G Disease Disease P82279 R769Q Neutral Neutral P82279 C948Y Disease Disease P82279 F144V Disease Neutral P82279 G850S Disease Disease P82279 C195F Disease Neutral P82279 L1071P Disease Disease P82279 V578E Disease Neutral P82279 R1383H Disease Neutral P82279 C1321S Disease Disease P82279 R905Q Neutral Neutral P82279 I1100R Disease Disease P82279 C250W Disease Neutral P82279 R764C Disease Disease P82279 R1331H Neutral Neutral P82279 Q679E Neutral Neutral P82279 L1107P Disease Disease P82279 I1100T Disease Neutral P82279 S1025I Disease Disease P82279 V162M Disease Neutral P82279 A161V Disease Neutral P82279 D584Y Disease Disease P82279 N1317H Disease Neutral P82279 N986I Disease Disease P82279 C681Y Disease Disease P82279 M741T Disease Disease P82279 G1103R Disease Disease P82279 R769H Neutral Neutral P82279 P836T Disease Disease P82279 G846R Disease Disease P82279 C1218F Disease Neutral P82279 L1107R Disease Disease P82279 I852T Disease Disease P82279 D837H Disease Neutral P82279 G959S Disease Neutral Q9NU23 K46E Neutral Neutral Q9NU22 A4044S Neutral Neutral Q9NU22 F440V Neutral Neutral Q9NU22 S1559N Neutral Neutral O00763 I2141V Neutral Neutral O00763 I552V Neutral Neutral O00763 A651T Neutral Disease O75829 V175I Neutral Neutral P42081 S170N Neutral Neutral P42081 A310T Neutral Neutral P42081 D323N Neutral Neutral Q9UHM6 G444D Neutral Neutral Q9UHM6 T394I Neutral Neutral Q9UHM6 P10L Neutral Neutral P01344 P173Q Neutral Neutral P01344 K120N Neutral Neutral P01344 K180N Neutral Neutral P35225 R130Q Neutral Neutral Q5SW79 G213S Neutral Neutral O95825 A39T Neutral Disease O43525 G310V Disease Disease O43525 W309R Disease Disease O43525 D305G Disease Disease Q5T442 P90S Disease Disease Q5T442 M286T Disease Disease Q5T442 Y272D Disease Neutral Q58G82 T97M Neutral Neutral Q8NBM8 E390D Neutral Neutral Q8NBM8 P5A Neutral Neutral Q8WV48 S190F Neutral Neutral Q8WV48 S242C Neutral Neutral Q8WV48 I220V Neutral Neutral Q8IYA7 R40H Neutral Neutral Q13057 S55Y Neutral Neutral O43194 A50V Neutral Neutral Q9BY79 R54G Neutral Neutral Q9BY79 G449S Neutral Neutral Q9BY79 I182T Disease Disease Q9BY79 I119V Neutral Neutral Q9BY79 Q514H Neutral Neutral Q9BY79 V136M Neutral Neutral Q86W50 N479S Neutral Neutral Q96DW6 R66G Neutral Disease Q9NZN4 G57S Neutral Neutral Q9HC16 Q275E Neutral Neutral Q9HC16 H186R Neutral Neutral Q8IUX4 A178T Neutral Neutral Q8IUX4 R48P Neutral Disease Q8IUX4 A108S Neutral Neutral Q9UH17 K62E Neutral Neutral Q9UH17 T146K Neutral Neutral Q8IUX4 V231I Neutral Neutral Q8IUX4 Q61L Neutral Neutral Q9UH17 S109A Neutral Neutral Q9UH17 P98L Neutral Neutral Q8IUX4 Y307C Neutral Disease Q8IUX4 P97L Neutral Neutral Q9NRM1 R763Q Neutral Neutral Q9NRM1 F576L Neutral Neutral Q9NRM1 I648T Neutral Neutral Q9NRM1 P724L Neutral Neutral P56192 A683D Neutral Disease P04278 R25H Neutral Neutral P04278 P185L Neutral Disease P04278 R22H Neutral Neutral P04278 D356N Neutral Neutral O42043 V348I Neutral Neutral O42043 C97Y Neutral Neutral O42043 V534I Neutral Neutral O42043 V272I Neutral Neutral Q96JA4 R584G Neutral Neutral Q96JA4 Y177N Neutral Neutral Q9BRU9 P215L Neutral Neutral Q9BRU9 K195Q Neutral Neutral Q9BRU9 H170R Neutral Neutral Q9P202 R423P Neutral Disease Q9P202 M613T Neutral Neutral Q9P202 H364R Neutral Neutral Q9P202 V783A Neutral Neutral Q9P202 N796K Neutral Neutral Q9P202 Q752H Neutral Neutral Q9P202 A440T Neutral Neutral Q9P202 T813M Neutral Neutral Q9P202 P562A Neutral Neutral Q04912 S434L Neutral Neutral Q04912 R504C Neutral Neutral Q04912 Q322R Neutral Neutral Q04912 R1335G Neutral Neutral Q04912 R523Q Neutral Neutral Q04912 G356D Neutral Neutral Q04912 Y1360C Neutral Disease Q04912 V900M Neutral Neutral Q04912 R185C Neutral Neutral Q04912 R75S Neutral Neutral Q04912 G465D Neutral Disease Q04912 R1304G Neutral Disease Q04912 P95T Neutral Neutral Q04912 N440S Neutral Neutral Q04912 Q613P Neutral Neutral Q8WZ74 L1213V Neutral Neutral Q8N3P4 H1165Y Neutral Neutral Q8N3P4 V83I Neutral Neutral Q8N3P4 I1364T Neutral Neutral Q8N3P4 R1372H Neutral Neutral Q8TAK5 V62I Neutral Neutral Q6UW10 N37S Neutral Neutral P45844 F668L Neutral Neutral P56177 S136C Neutral Disease P30291 S472I Neutral Disease P30291 G210C Neutral Neutral Q9H8H2 R843Q Neutral Neutral Q9H8H2 I799V Neutral Neutral Q8NCV1 G44E Neutral Neutral Q8NCV1 G307R Neutral Neutral Q08752 L302I Neutral Neutral Q08752 G335E Neutral Neutral Q08752 R49C Neutral Disease Q9NRI5 R264Q Neutral Neutral Q9NRI5 G5V Neutral Neutral Q9NRI5 S704C Neutral Neutral Q9NRI5 L607F Neutral Neutral O60393 G482S Neutral Neutral O60393 F517L Neutral Neutral O60393 R360Q Neutral Neutral O60393 R355H Disease Neutral O60393 D452N Neutral Neutral P50416 L484P Disease Disease P50416 R123C Disease Disease P50416 Y498C Disease Disease P50416 P479L Disease Disease P50416 C304W Disease Disease P50416 E360G Disease Neutral P50416 D454G Disease Disease Q92523 I66V Neutral Neutral P50416 A275T Neutral Neutral Q92523 E531K Neutral Neutral Q92523 G320D Neutral Disease Q92523 S427C Neutral Disease P50416 R357W Disease Disease P50416 G710E Disease Disease P50416 A414V Disease Disease P50416 G709E Disease Neutral Q92523 S664Y Neutral Disease P50416 T314I Disease Disease Q96P20 F523C Disease Disease Q86W25 N781S Neutral Disease Q96P20 M662T Disease Neutral Q96P20 F573S Disease Disease Q96P20 A439T Disease Neutral Q96P20 L305P Disease Disease Q96P20 E627G Disease Neutral Q86W25 Q247R Neutral Disease Q9NX02 A1052E Neutral Neutral Q96P20 V198M Disease Neutral Q96P20 T436N Disease Disease Q96P20 A439V Disease Disease Q96P20 F309S Disease Neutral Q9NX02 R364K Neutral Disease Q96P20 Y859C Disease Neutral Q96P20 A352V Disease Disease Q96P20 D303N Disease Disease Q96P20 T348M Disease Neutral Q96P20 R260W Disease Disease Q96P20 G569R Disease Disease Q96P20 H358R Disease Neutral P56159 Y85N Neutral Disease P56159 T366A Neutral Neutral Q5T4S7 T1107A Neutral Neutral Q5T4S7 G4924R Disease Disease Q5T4S7 V5084M Neutral Neutral Q5T4S7 M4867L Neutral Neutral Q6NXR4 L425R Neutral Neutral Q6NXR4 E63G Neutral Neutral Q96JM4 I29N Neutral Neutral Q96JM4 A912T Neutral Neutral Q96JM4 C83Y Neutral Neutral P78368 E194G Neutral Neutral Q9HCP0 V329I Neutral Neutral P78368 I196T Neutral Neutral Q9HCP0 R206K Neutral Disease P78368 Y206H Neutral Disease P78368 Y206C Neutral Disease P78368 R207S Neutral Disease P78368 F189L Neutral Disease P78368 E208Q Neutral Disease P78368 R217C Neutral Disease P78368 T223M Neutral Neutral Q68CR1 I401V Neutral Neutral Q15527 G213S Neutral Neutral Q63HN1 D203E Neutral Neutral Q63HN1 V229M Neutral Neutral Q63HN1 N72K Neutral Disease P23945 N680S Neutral Neutral P23945 I545T Disease Disease P23945 S128Y Disease Disease P23945 A419T Disease Neutral P23945 P519T Disease Disease P23945 D224V Disease Disease P23945 F591S Disease Neutral P23945 L601V Disease Neutral P23945 R573C Disease Disease P23945 P348R Disease Disease P23945 T449A Disease Neutral P23945 D567N Disease Disease P23945 T449I Disease Disease P23945 A189V Disease Disease P23945 S524R Neutral Neutral P23945 T307A Neutral Neutral P23945 I160T Disease Disease Q96BN8 S227N Neutral Neutral Q86XN7 V571A Neutral Neutral Q86XN7 S847T Neutral Neutral P28329 R482G Disease Disease P28329 V506L Disease Neutral P28329 L210P Disease Disease P28329 I305T Disease Neutral P28329 E441K Disease Disease P28329 S498L Disease Disease P28329 P211A Disease Neutral P28329 R560H Disease Disease P28329 I336T Disease Disease P28329 A120T Neutral Neutral P28329 A392G Neutral Neutral P28329 R420C Disease Disease P09237 G137D Neutral Disease P09237 R77H Neutral Neutral P09237 P241L Neutral Disease Q9NRE1 I260M Neutral Neutral Q9NRE1 K43E Neutral Neutral Q99542 T491M Neutral Neutral Q99542 P488T Neutral Neutral Q99542 R103C Neutral Disease Q05655 M494V Neutral Disease Q05655 S375F Neutral Disease Q05655 N348S Neutral Disease Q05655 L410F Neutral Neutral Q05655 M593V Neutral Neutral Q53GQ0 S280L Neutral Disease Q3SXM5 C327S Neutral Neutral Q3SXM5 P248S Neutral Disease Q9ULE6 R721C Neutral Neutral Q9ULE6 S141L Neutral Neutral P30038 V470I Neutral Neutral P30038 P16L Neutral Neutral P30038 S352L Disease Disease Q9Y4J8 P121L Disease Neutral Q96EY4 Q65P Neutral Neutral Q96EY4 I176T Neutral Neutral O15169 G650S Disease Neutral O15169 P345L Disease Disease O15169 G425S Disease Neutral O15169 L106R Disease Disease Q9Y4K4 I446V Neutral Neutral Q9Y4K4 R552Q Neutral Neutral Q9Y4K4 A334T Neutral Neutral Q9Y4K4 P407L Neutral Neutral Q9Y4K4 T633M Neutral Disease Q9Y4K4 N473K Neutral Neutral P22223 Q563H Neutral Neutral P55287 T255M Neutral Neutral P22223 R503H Disease Disease P22223 V237M Neutral Neutral Q9ULB4 Y6C Neutral Neutral P22223 R477H Neutral Disease Q9ULB4 A38V Neutral Neutral P22223 N322I Disease Neutral P55287 M275I Neutral Neutral P33151 T517I Neutral Neutral P33151 I503T Neutral Neutral P55289 E86K Neutral Neutral P55287 S373A Neutral Disease O75695 C108G Disease Disease O75695 C86Y Disease Disease O75695 R118C Disease Disease O75695 D338Y Neutral Neutral O75695 E138G Disease Disease O75695 L253R Disease Disease O75695 P95L Disease Disease O75695 R282W Neutral Neutral O75695 L188P Disease Disease O75695 C67Y Disease Disease O75695 R118H Disease Disease O75695 R118L Disease Disease Q9H3U5 P24S Neutral Neutral Q9H3U5 K168E Neutral Disease Q9H3U5 I220V Neutral Neutral Q92954 R180W Neutral Disease P14415 T199A Neutral Neutral Q8NHS3 G385R Neutral Neutral Q8NHS3 A423V Neutral Neutral Q8NHS3 V109G Neutral Disease Q8NHS3 G310D Disease Disease Q8NHS3 G429D Disease Disease Q6AZY7 F467L Neutral Neutral Q6AZY7 M325T Neutral Neutral Q6AZY7 P551S Neutral Neutral Q6AZY7 R130Q Neutral Neutral Q6AZY7 V428I Neutral Neutral Q6AZY7 R423Q Neutral Neutral P18505 H421Q Neutral Neutral P18505 I429N Neutral Disease Q9Y6X6 M385T Neutral Neutral Q9Y6X6 P831A Neutral Neutral Q6P1N0 T801M Neutral Neutral Q6P1N0 T635S Neutral Neutral Q6P1N0 T339P Neutral Neutral Q96F81 E103K Neutral Neutral Q6ZRQ5 N419D Neutral Neutral Q6ZRQ5 T564M Neutral Neutral Q6ZRQ5 P1015L Neutral Neutral Q6ZRQ5 V875A Neutral Neutral Q7Z6E9 V555A Neutral Neutral Q9H095 A112D Neutral Neutral Q96AV8 L72F Neutral Neutral Q96AV8 M626V Neutral Neutral Q96AV8 Q854H Neutral Neutral Q5VV43 A311T Disease Neutral Q5VV43 T142P Neutral Neutral Q5VV43 G919A Neutral Neutral Q8N292 A83T Neutral Neutral O95551 R268Q Neutral Neutral O95551 Q249E Neutral Neutral Q9HD43 K781N Neutral Neutral Q9HD43 E823K Neutral Disease Q9HD43 I1076V Neutral Neutral Q9HD43 L543F Neutral Neutral Q9HD43 H348Y Neutral Neutral Q86WI1 H923R Neutral Neutral Q86WI1 D3607E Neutral Neutral Q86WI1 A957E Neutral Neutral Q86WI1 Y943H Neutral Neutral Q86WI1 T1192A Neutral Neutral Q86WI1 W373C Neutral Disease Q86WI1 H3050Q Neutral Neutral Q86WI1 Y440H Neutral Neutral Q86WI1 T1539R Neutral Neutral Q86WI1 I3411V Neutral Neutral Q86WI1 R1514S Neutral Neutral Q86WI1 L3862F Neutral Neutral Q86WI1 V4220I Neutral Neutral Q86WI1 L1965V Neutral Neutral Q86WI1 V3080I Neutral Neutral Q9H875 D106Y Neutral Neutral Q9H875 S7A Neutral Neutral O43150 E748D Neutral Neutral Q96LQ0 T83I Neutral Neutral O14940 R319Q Disease Disease O14940 R73W Disease Disease O14940 G324E Disease Disease O14940 G127D Disease Disease O14940 G126D Disease Disease Q9UHR4 S460T Neutral Neutral P31930 N301S Neutral Neutral P31930 D215H Neutral Disease Q494U1 R539P Neutral Neutral P12111 G1679E Disease Disease P12111 D2831H Neutral Neutral Q9UQ90 T503A Neutral Neutral Q9UQ90 R688Q Neutral Disease Q5T6L9 S540G Neutral Neutral Q01094 R252H Neutral Neutral Q01094 G393S Neutral Neutral Q01094 V276M Neutral Neutral Q01094 T311N Neutral Neutral Q8WVX3 Q17R Neutral Neutral Q8WVX3 P32H Neutral Neutral P19623 L149V Neutral Neutral O60443 V207M Neutral Neutral O60443 P142T Neutral Neutral Q5U623 A543T Neutral Neutral Q5U623 T537I Neutral Neutral Q96KR6 P126S Neutral Neutral Q9BXK5 P360S Neutral Neutral Q9BXK5 I55V Neutral Neutral Q8TC90 I379M Neutral Neutral Q13472 C596Y Neutral Disease Q9UHP6 T42M Neutral Neutral P51649 V487E Disease Disease P51649 P382L Disease Disease P51649 G268E Disease Disease P51649 N255S Disease Disease P51649 H180Y Neutral Disease P51649 G533R Disease Disease P51649 C93F Disease Disease P51649 V406I Neutral Neutral P51649 C223Y Disease Disease P51649 T233M Disease Disease P51649 P182L Neutral Disease P51649 P382Q Disease Disease P51649 G409D Disease Disease P51649 G176R Disease Disease P51649 N335K Disease Disease O75912 L153F Neutral Neutral Q9Y3Q4 S672R Disease Neutral P63000 D63G Neutral Disease P63000 T108I Neutral Neutral P15153 D57N Disease Disease P63000 V93G Neutral Disease P63000 V182E Neutral Neutral P63000 N26D Neutral Neutral P63000 K133E Neutral Disease P63000 F28L Neutral Disease P63000 P180S Neutral Neutral P63000 V93I Neutral Neutral P63000 A59T Neutral Disease P63000 K130R Neutral Neutral P63000 T135I Neutral Neutral Q96EA4 S586L Neutral Neutral Q96EA4 H508Y Neutral Neutral P57773 V497I Neutral Neutral P40818 A827G Neutral Neutral P40818 D443G Neutral Neutral Q401N2 A152T Neutral Neutral Q6ZS82 A96S Neutral Neutral P24298 H14N Neutral Neutral Q00325 G72E Disease Disease P28290 P836L Neutral Neutral P28290 R833W Neutral Neutral Q7Z5H3 T410K Neutral Neutral Q7Z5H3 R612C Neutral Neutral Q96F05 A150T Neutral Neutral Q96F05 G97V Neutral Neutral Q93015 R145S Disease Disease Q93015 T207S Disease Neutral P21854 P234L Neutral Disease Q7Z478 P630H Neutral Disease P13598 R256Q Neutral Neutral P13598 R199H Neutral Neutral P13598 A37T Neutral Neutral Q7Z4H9 V161L Neutral Neutral Q7Z4H9 G71R Neutral Neutral Q7Z4H9 V198M Neutral Neutral Q7Z4H9 G237S Neutral Neutral Q7Z4H9 R127Q Neutral Neutral P18065 A140D Neutral Neutral Q5XG87 N326S Neutral Neutral Q5XG87 G396S Neutral Neutral Q8N5V2 M111T Neutral Neutral Q8N5V2 R78G Neutral Neutral O95625 G44S Neutral Neutral Q9BUD6 P40L Neutral Neutral Q9BUD6 L242V Neutral Neutral Q9BUD6 E122A Neutral Neutral Q9C0D4 S105P Neutral Neutral Q9C0D4 S523N Neutral Neutral Q03468 W851R Disease Neutral Q03468 P1042L Disease Neutral Q03468 R670W Disease Disease Q03468 V957G Disease Disease Q92614 A958V Neutral Neutral Q86WV1 S242G Neutral Neutral O75563 A202S Neutral Neutral O75563 S253T Neutral Neutral Q86WV1 S161G Neutral Neutral Q6ZUT3 A226T Disease Neutral Q6ZUT3 A266P Disease Disease Q6ZUT3 S281L Neutral Neutral Q6ZUT3 S340L Disease Neutral Q6ZUT3 R468H Neutral Neutral Q6ZUT3 G24E Disease Disease Q6ZUT3 G24R Disease Disease Q6ZUT3 Y301C Disease Disease Q6ZUT3 C271Y Disease Disease Q6ZUT3 N221D Disease Disease Q6ZUT3 L142R Disease Disease Q6ZUT3 L231V Disease Neutral O94813 S1277F Neutral Disease O94813 S636P Neutral Disease O75094 R395Q Neutral Disease O75094 E994G Neutral Neutral O75094 G618S Neutral Neutral Q9BQ31 V225L Neutral Neutral Q9BQ31 A450T Neutral Neutral P19526 D148Y Neutral Disease P19526 Y154H Neutral Disease P19526 Y241H Neutral Disease P19526 A12V Neutral Neutral P19526 E348K Neutral Disease Q2LD37 T4352A Neutral Neutral Q2LD37 I978T Neutral Neutral Q2LD37 T4786A Neutral Neutral P29033 L79P Disease Disease P29033 D179N Disease Disease P29033 F191L Neutral Disease P29033 D50Y Disease Disease P29033 I203K Disease Disease P29033 R75W Disease Disease P29033 M34T Neutral Disease P29033 C202F Disease Disease P29033 M93I Disease Disease P29033 R32H Disease Disease P29033 N54K Disease Disease P29033 W77R Disease Disease P29033 R32L Neutral Disease P29033 S17F Disease Disease P29033 R127H Neutral Neutral P29033 C169Y Neutral Disease P29033 I203T Neutral Neutral P29033 G160S Neutral Disease P29033 D66H Disease Disease P29033 D159V Disease Disease P29033 E129K Disease Disease P29033 I111T Neutral Neutral P29033 L214P Disease Disease P29033 G12R Disease Disease P29033 D50N Disease Neutral P29033 S113R Disease Neutral P29033 L90P Disease Disease P29033 T123N Neutral Neutral P29033 F83L Neutral Disease P29033 G59A Disease Disease P29033 W44C Disease Disease P29033 G59S Disease Disease P29033 A197S Disease Neutral P29033 R184Q Disease Disease P29033 R75Q Disease Disease P29033 V27I Neutral Neutral P29033 Q80K Disease Disease P29033 V37I Disease Neutral P29033 R143W Disease Disease P29033 R143Q Disease Disease P29033 E114G Neutral Neutral P29033 V84L Disease Disease P29033 R184P Disease Disease P29033 R165W Neutral Disease P29033 V95M Disease Disease P29033 W44S Disease Disease P29033 V178A Disease Disease O95990 P19L Disease Disease O95990 L15M Disease Neutral P15529 S240P Disease Disease P15529 P165S Disease Disease Q5VU97 M414T Neutral Neutral O75351 I58M Neutral Disease Q8IZF5 A404T Neutral Neutral Q96NY9 R180P Neutral Neutral Q96NY9 L189F Neutral Neutral Q96NY9 R350W Neutral Disease Q96NY9 R37H Neutral Neutral Q96NY9 Q481H Neutral Neutral P16278 R59H Disease Disease P16278 G494C Disease Disease P16278 L162S Disease Neutral P16278 G579D Disease Disease P16278 R121S Disease Disease P16278 Y316C Disease Disease P16278 R457Q Disease Disease P16278 W509C Disease Disease P16278 Q408P Disease Disease P16278 R201H Disease Neutral P16278 T500A Disease Neutral P16278 D491N Disease Disease P16278 P549L Disease Disease P16278 D214Y Disease Neutral P16278 D151Y Disease Disease P16278 W273L Disease Disease P16278 R482H Disease Disease P16278 R521C Neutral Disease P16278 L155R Disease Disease P16278 R49C Disease Disease P16278 R590H Disease Disease P16278 R208C Disease Disease P16278 Y83H Disease Disease P16278 R201C Disease Disease P16278 Y270D Disease Disease P16278 Y591C Disease Disease P16278 R68W Disease Disease P16278 R59C Disease Disease P16278 R590C Disease Disease P16278 G134V Disease Disease P16278 L10P Neutral Neutral P16278 G438E Disease Disease P16278 P263S Disease Disease P16278 K578R Disease Disease P16278 G123R Disease Disease P16278 R482C Disease Disease P16278 N266S Disease Neutral P16278 T239M Disease Disease P16278 H281Y Disease Disease P16278 E632G Disease Neutral P16278 V240M Disease Neutral P16278 R148S Disease Disease P16278 D491Y Disease Disease P16278 S532G Neutral Neutral P16278 I51T Disease Disease P16278 T82M Disease Disease P16278 Y591N Disease Disease P16278 G272D Disease Disease P16278 V216A Disease Neutral P16278 D332N Disease Disease P16278 N484K Disease Disease O75459 L75P Neutral Neutral O60729 I341T Neutral Disease O60729 I302T Neutral Disease Q8IW41 M67I Neutral Neutral Q8IW41 R282K Neutral Neutral Q96MC9 P233S Neutral Neutral Q96MC9 T259M Neutral Neutral Q96MC9 G213A Neutral Neutral P17020 R227H Neutral Neutral P17020 E105K Neutral Neutral O95170 F143L Neutral Neutral P23434 N73S Neutral Neutral P23434 L21S Neutral Neutral Q8WXI8 S32G Neutral Disease Q9H2A7 V181A Neutral Neutral Q9H2A7 I123T Neutral Neutral O95810 E130D Neutral Neutral P26358 H97R Neutral Neutral Q9UHN6 I1010V Neutral Neutral Q9UHN6 R291H Neutral Neutral Q9UHN6 S1254N Neutral Neutral Q9UHN6 P765S Neutral Neutral Q9UHN6 D423E Neutral Neutral Q9UHN6 G1280D Neutral Neutral Q9UHN6 R245K Neutral Neutral Q9BYZ2 P30L Neutral Disease Q9BYZ2 I326T Neutral Neutral Q9BYZ2 V14M Neutral Neutral Q06710 C57Y Disease Disease Q06710 L62R Disease Disease Q06710 R31H Disease Disease Q06710 F329L Neutral Neutral Q06710 Q40P Disease Disease Q9Y233 L303P Neutral Disease Q9Y215 P59Q Disease Disease Q9Y215 C444Y Disease Disease Q9Y215 Y430S Disease Disease Q9Y215 D342E Disease Neutral Q9Y215 R410Q Disease Neutral Q6S9Z5 R173H Neutral Disease Q16594 T6M Neutral Neutral Q8NBW4 T182S Neutral Neutral Q9UIJ5 M356I Disease Neutral Q9UIJ5 S306F Disease Neutral Q06265 S425T Neutral Neutral Q8TDU9 L329S Neutral Neutral Q3KQV3 Q110R Neutral Neutral Q9UPE1 G114E Neutral Neutral Q9UPE1 E233K Neutral Disease Q9UPE1 R101C Neutral Disease Q5VZ89 N1107H Neutral Neutral Q5VZ89 T1030A Neutral Neutral Q8N4F7 M159V Neutral Neutral Q8N4F7 I315M Neutral Neutral Q8N4F7 L307F Neutral Neutral Q8N4F7 N322I Neutral Disease P51580 Y180F Neutral Neutral P51580 A154T Disease Disease P51580 A80P Disease Disease P51580 Y240C Disease Disease P51580 L49S Neutral Disease P51580 H227Q Disease Neutral P51580 R215H Disease Neutral Q3KNS1 M584I Neutral Disease Q3KNS1 C407G Neutral Disease Q3KNS1 R372K Neutral Neutral Q3KNS1 M521T Neutral Neutral Q3KNS1 T126A Neutral Neutral Q3KNS1 A224G Neutral Neutral Q3KNS1 D473G Neutral Neutral Q3KNS1 L152P Neutral Disease Q9NQ36 P843R Neutral Disease Q9NQ36 Q712H Neutral Neutral Q8IWY4 G398R Neutral Disease Q9NQ36 T591M Neutral Neutral Q8IWY4 S648P Neutral Neutral Q9NQ36 T791S Neutral Neutral Q9NQ36 V752G Neutral Disease O14523 R413W Neutral Neutral O75072 C250G Disease Disease O75072 R307Q Disease Disease O75072 Q358P Disease Neutral O75072 R179T Disease Disease Q99705 N32D Neutral Neutral Q99705 Y250H Neutral Neutral Q99705 T411M Neutral Neutral Q99705 P377S Neutral Disease Q99705 T25M Neutral Neutral Q99705 R210H Neutral Neutral Q99705 D28V Neutral Neutral Q99705 T305M Neutral Neutral Q7Z7J5 R131Q Neutral Neutral P24530 W276C Disease Neutral P24530 G57S Disease Neutral P24530 P383L Disease Disease P24530 S305N Disease Neutral P24530 F292L Disease Neutral P24530 R76M Neutral Neutral P24530 F112V Neutral Disease P24530 R319W Disease Disease P24530 T244M Neutral Disease P24530 M374I Disease Disease P24530 A183G Disease Neutral P24530 P5T Neutral Neutral P24530 L17F Neutral Neutral P24530 L7Q Neutral Neutral O15273 P90L Disease Neutral O15273 L74H Neutral Neutral O15273 R87Q Disease Neutral O15273 R153H Disease Neutral O15273 T137I Disease Neutral O15273 E132Q Disease Neutral O15273 R70W Disease Neutral P32247 T53P Neutral Disease P32247 L162Q Neutral Neutral Q9H1Q7 Q22H Neutral Neutral Q8N1I2 V47L Neutral Neutral Q13253 E48K Disease Neutral Q13253 I220N Disease Disease Q13253 R167G Disease Neutral Q13253 Y222C Disease Disease Q13253 C184Y Disease Disease Q13253 A36P Disease Neutral Q13253 W217G Disease Disease Q13253 P35A Disease Neutral Q13253 P35S Disease Neutral Q13253 W205C Disease Disease Q13253 G189C Disease Neutral Q13253 R204L Disease Neutral Q13253 P187S Disease Neutral Q13253 P35R Disease Disease Q13253 Y222D Disease Disease Q13253 P223L Disease Disease Q13258 E301A Neutral Neutral Q13258 R7C Neutral Disease Q7Z4F1 R48W Neutral Neutral Q7Z4F1 M139V Neutral Neutral Q6MZW2 R158H Neutral Neutral Q6MZW2 M757T Neutral Neutral Q02487 N11S Neutral Neutral Q02487 I776V Neutral Neutral Q9Y2I8 I225V Neutral Neutral Q5H9L4 S308G Neutral Neutral Q5H9L4 R458H Neutral Neutral Q5H9L4 E61K Neutral Neutral Q5H9L4 L34P Neutral Neutral O15254 D497N Neutral Neutral O15254 E34A Neutral Neutral P21452 R375H Neutral Neutral P21452 I23T Neutral Neutral Q8NFQ5 P149T Neutral Neutral Q8NFQ5 T16M Neutral Neutral Q8NFQ5 V97I Neutral Neutral Q8NFQ5 S347G Neutral Neutral Q9UHF4 V259I Neutral Neutral Q9UHF4 L382F Neutral Neutral Q7L3V2 R116H Neutral Neutral Q7L3V2 D123Y Neutral Disease Q15760 I189V Neutral Neutral P10916 A13T Disease Disease P10916 P95A Disease Neutral P10916 R58Q Disease Neutral P10916 F18L Disease Disease P10916 D166V Disease Disease P10916 E22K Disease Neutral P10916 G57R Neutral Disease Q02297 M463K Neutral Neutral Q02297 R38Q Neutral Neutral P42772 A50V Disease Neutral P42772 G47E Disease Disease Q7Z3Z2 R47C Neutral Neutral Q7Z3Z2 D195V Neutral Neutral Q7Z3Z2 G35R Neutral Neutral Q7Z3Z2 R167K Neutral Neutral Q7Z3Z2 R68W Neutral Neutral Q12982 S24T Neutral Neutral Q96CU9 V145I Neutral Neutral Q96CU9 A343P Neutral Disease P51857 L106P Disease Disease O60218 P87S Neutral Neutral P17516 S145C Neutral Neutral P15121 L73V Neutral Neutral P15121 H42L Neutral Disease P42330 R66Q Neutral Disease P52895 L172Q Neutral Neutral Q96JD6 K86R Neutral Neutral O60218 D313N Neutral Neutral Q5T2L2 R50H Neutral Disease P17516 C170Y Neutral Disease P42330 P180S Neutral Neutral P17516 G135E Neutral Disease P51857 P198L Disease Neutral P17516 L311V Neutral Neutral P15121 G204S Neutral Disease O60218 M286T Neutral Disease P15121 T288I Neutral Neutral P42330 R170C Neutral Neutral P17516 R250Q Neutral Disease P42330 M175I Neutral Neutral P15121 I15F Neutral Disease Q96JD6 C52G Neutral Neutral P42330 Q5H Neutral Neutral O43914 Y111H Neutral Neutral Q8IWL1 Q223K Neutral Neutral P11226 G57E Neutral Disease Q8IWL2 R219W Neutral Disease Q8IWL2 V19A Neutral Neutral Q8IWL2 N9T Neutral Neutral P11226 G54D Neutral Disease Q8IWL1 V50L Neutral Neutral Q8IWL2 Q223K Neutral Neutral P11226 R52C Neutral Disease Q8IWL1 N9T Neutral Neutral Q8IWL1 A91P Neutral Neutral Q8IWL2 L50V Neutral Neutral Q9NYK1 Q11L Neutral Neutral Q9NR97 M10V Neutral Neutral Q9NYK1 A448V Neutral Neutral Q9BQE5 I245V Neutral Neutral Q9BQE5 R182C Neutral Neutral Q9H6L2 L6V Neutral Neutral P55290 L121S Neutral Neutral Q96EZ4 A159V Neutral Neutral Q05823 G59S Neutral Neutral Q05823 R592H Neutral Disease Q05823 D541E Neutral Neutral Q05823 A289T Neutral Neutral Q05823 R462Q Neutral Neutral Q05823 I97L Neutral Neutral Q05823 S406F Neutral Neutral Q7Z6J9 N347K Neutral Neutral Q7Z6J9 D4E Neutral Neutral Q7Z6J9 H38Q Neutral Neutral Q7Z6J9 V437A Neutral Neutral Q96AQ6 G357D Neutral Neutral Q6UXZ3 R189W Neutral Disease Q08708 T71I Neutral Disease Q6P1M3 R748H Neutral Neutral Q6P1M3 G1001S Neutral Neutral Q9NYI0 T186M Neutral Neutral Q9NYI0 T186P Neutral Neutral Q9NYI0 P293L Neutral Neutral Q8IUI8 L389P Neutral Disease Q9NVU7 C575S Neutral Neutral Q9NVU7 V660I Neutral Neutral Q9NVU7 A490D Neutral Neutral Q9NVU7 K258Q Neutral Neutral P01042 G163S Neutral Neutral P01042 L212P Neutral Neutral P01042 M178T Neutral Neutral P01042 I197M Neutral Neutral Q15029 G773V Neutral Disease Q15024 L274V Neutral Neutral Q15024 R169Q Neutral Neutral Q8IY50 S231C Neutral Neutral Q86XK2 T126S Neutral Neutral P26951 V323L Neutral Neutral P26951 E77G Neutral Neutral P26951 S123T Neutral Neutral P26951 A12T Neutral Neutral P22061 I120V Neutral Neutral Q8N3K9 P4063L Neutral Disease Q8N3K9 K2906N Neutral Neutral Q8N3K9 D190G Neutral Neutral Q8N3K9 K3583E Neutral Neutral Q8N3K9 T2693I Neutral Neutral Q8N3K9 G591D Neutral Neutral Q8N3K9 K2383E Neutral Neutral Q8N3K9 A1333V Neutral Neutral Q8N3K9 A1875V Neutral Neutral Q8N3K9 H3358Q Neutral Neutral Q8N3K9 L1669S Neutral Neutral Q8N3K9 G349D Neutral Neutral Q8N3K9 S1920G Neutral Neutral Q8N3K9 V1006A Neutral Neutral Q8N3K9 I1380V Neutral Neutral Q8N3K9 D1917G Neutral Neutral Q8N3K9 Y64C Neutral Neutral Q8N3K9 A1567E Neutral Neutral Q8N3K9 I1713N Neutral Neutral Q8N3K9 A1295V Neutral Neutral Q8N3K9 I1721V Neutral Neutral Q8N3K9 G2935R Neutral Neutral Q8N3K9 S1599A Neutral Neutral Q8N3K9 Q175H Neutral Neutral Q8N3K9 V2262L Neutral Neutral Q8N3K9 I1309V Neutral Neutral Q8N3K9 R3927Q Neutral Neutral Q8N6T3 V184M Neutral Neutral O94993 V749M Neutral Neutral P19827 S263T Neutral Neutral P19827 Q595R Neutral Neutral P19827 E585V Neutral Disease P19827 G695C Neutral Disease P19827 D844E Neutral Neutral P29372 A258V Neutral Neutral P29372 K22Q Neutral Neutral P29372 Y71H Neutral Neutral P29372 R141Q Neutral Disease P29372 R120C Neutral Disease P29372 A298S Neutral Neutral P29372 P64L Neutral Neutral Q8N137 P578Q Neutral Neutral Q9Y5I7 L145P Disease Disease Q9Y5I7 F232C Disease Disease Q9Y5I7 L151P Disease Disease Q9Y5I7 A209T Disease Disease Q9Y5I7 R149L Disease Disease Q9Y5I7 L151F Disease Neutral Q9Y5I7 G198A Disease Neutral Q9Y5I7 H141D Disease Neutral Q9Y5I7 S235P Disease Disease Q9Y5I7 G239R Disease Disease Q9Y5I7 G191R Disease Disease Q9Y5I7 L167P Disease Disease Q9Y5I7 R216T Disease Disease Q9Y5I7 G233D Disease Disease Q9Y5I7 L151W Disease Neutral Q9Y5I7 M71R Disease Disease Q9Y5I7 G198D Disease Disease Q9Y5I7 S235F Disease Disease Q9NVZ3 D149A Neutral Disease Q8NC96 D224N Neutral Neutral Q9NNX1 K296R Neutral Neutral P04114 R490W Disease Disease P04114 R3527Q Disease Disease P04114 R3558C Disease Disease Q6Q788 G185C Neutral Neutral Q6Q788 S19W Neutral Neutral Q6Q788 D37E Neutral Neutral Q6Q788 V153M Neutral Neutral Q6ZQW0 R230W Neutral Disease O75061 S671N Neutral Neutral Q99502 D429G Disease Disease Q99502 L583P Disease Disease Q99502 G426S Disease Disease Q99502 L505R Disease Disease Q99502 P20A Neutral Neutral Q99502 S487P Disease Disease Q99502 R440Q Disease Disease Q7Z353 F397S Neutral Neutral Q7Z353 A193T Neutral Neutral Q96ST8 V398A Neutral Neutral Q96ST8 R194W Neutral Neutral Q8TAT5 P117R Neutral Neutral Q8TAT5 R520G Neutral Neutral Q8TAT5 Q172H Neutral Neutral Q8TAT5 H471Q Neutral Neutral Q8TAT5 H286R Neutral Neutral Q8TAT5 I346V Neutral Neutral Q8TAT5 V76M Neutral Neutral Q8TAT5 A547S Neutral Disease Q8TAT5 H556R Neutral Neutral Q8TAT5 L443P Neutral Neutral Q8TAT5 R38C Neutral Neutral Q5VTL7 V354A Neutral Neutral Q5VTL7 S310N Neutral Neutral Q5VTL7 P686L Neutral Neutral Q5VTL7 N368S Neutral Neutral Q9UDX4 D335E Neutral Neutral O76054 R11K Neutral Neutral Q9UDX4 I103T Neutral Disease Q9UDX3 S3G Neutral Neutral Q9UDX4 R214H Neutral Disease A6NC57 C251R Neutral Disease A6NC57 E392K Neutral Disease A6NC57 A599T Neutral Neutral A6NC57 A174S Neutral Disease P06400 R358G Disease Neutral P06400 E746G Neutral Neutral P06400 K616E Disease Neutral P06400 R661W Disease Disease P06400 S567L Disease Disease P06400 H549Y Disease Disease P06400 M457R Disease Disease P06400 Q436K Neutral Neutral P06400 C712R Disease Disease P06400 K447Q Disease Neutral P06400 A525G Neutral Disease P06400 R500G Disease Neutral P06400 V654E Disease Disease P06400 R358Q Disease Neutral P06400 A635P Disease Neutral P06400 C706Y Disease Disease P06400 E72Q Disease Neutral P06400 E137D Disease Neutral P06400 K530R Disease Disease P06400 G310E Disease Neutral P06400 L662P Disease Disease P06400 I185T Disease Neutral P06400 H673P Disease Disease P06400 N803K Disease Disease P06400 L657P Disease Disease P06400 Q685P Disease Disease P12318 H167R Neutral Neutral P06746 P242R Neutral Disease Q9UN88 L15I Neutral Neutral Q9UN88 F478I Neutral Neutral P31358 I41M Neutral Neutral P49917 I658V Neutral Neutral P49917 A3V Neutral Neutral P49917 R278H Disease Disease P49917 L539F Neutral Neutral P49917 D62H Neutral Disease P49917 P231S Neutral Neutral P49917 A857T Neutral Neutral P49917 G469E Disease Disease P49917 T9I Neutral Neutral Q14957 R1209S Neutral Neutral Q53R41 E384Q Neutral Neutral Q53R41 M467V Neutral Neutral Q53R41 C446G Neutral Disease A8MXV4 R43Q Neutral Neutral P54710 G41R Disease Disease Q9GZX7 M139V Disease Disease Q9GZX7 R25C Neutral Disease Q9GZX7 R24W Disease Disease Q9GZX7 F151S Disease Disease Q9GZX7 L106P Disease Disease Q9GZX7 W80R Disease Disease Q9BQ65 Q250E Neutral Neutral Q9H0E9 T490M Neutral Neutral Q9Y6S9 R21Q Neutral Neutral Q9Y6S9 P121L Neutral Neutral Q9Y6S9 R332W Neutral Neutral O76024 V871M Neutral Neutral O76024 I333V Neutral Neutral O76024 R708C Neutral Disease O76024 P16L Neutral Neutral O76024 I720V Neutral Neutral O76024 P292S Disease Neutral O76024 G576S Neutral Neutral O76024 K634T Disease Neutral O76024 R611H Neutral Neutral O76024 G107R Neutral Disease O76024 A559T Neutral Neutral O76024 G437R Disease Neutral O76024 P885L Disease Neutral O76024 G695V Disease Disease O76024 Y669C Disease Disease O76024 A133T Disease Neutral O76024 I802V Neutral Neutral O76024 L829P Disease Disease O76024 R629W Disease Neutral O76024 P724L Disease Disease O76024 G780R Disease Neutral O76024 R818C Disease Neutral O76024 R456H Neutral Disease O76024 K193Q Neutral Neutral O76024 A602V Neutral Neutral O76024 G736S Disease Disease O76024 W700C Disease Disease O76024 G831D Disease Disease O76024 Y110N Disease Disease O76024 S443I Disease Disease O76024 R457S Disease Disease O76024 E737K Neutral Disease O76024 A326V Neutral Neutral O76024 C690R Disease Disease O76024 A126T Disease Neutral O76024 A716T Disease Neutral O76024 V779M Disease Neutral O76024 I296S Disease Neutral O76024 A684V Neutral Neutral O76024 A58V Disease Neutral O76024 G674R Neutral Disease O76024 E169K Disease Neutral O76024 P504L Disease Disease O76024 T699M Disease Neutral Q9H147 A183T Neutral Neutral Q16854 L250S Disease Disease Q16854 E227K Disease Disease Q16854 R142K Disease Disease Q8N5U0 P242S Neutral Neutral P23582 R82Q Neutral Neutral Q96GX9 R7W Neutral Neutral Q96GX9 M181V Neutral Neutral Q96GX9 C76Y Neutral Disease Q96GX9 H23R Neutral Disease Q9HB14 G389A Neutral Neutral Q9BVM2 L156S Neutral Neutral Q9BVM2 S56R Neutral Neutral Q9Y2T7 G9V Neutral Neutral Q9Y2T7 S63P Neutral Neutral P16989 T75A Neutral Neutral P22570 P352S Neutral Neutral P22570 G213V Neutral Neutral P22570 R123Q Neutral Disease P22570 T472A Neutral Neutral P22570 R251W Neutral Neutral P22570 T345M Neutral Disease P22570 P248L Neutral Neutral P22570 R7L Neutral Neutral P22570 R301C Neutral Disease P01583 A114S Neutral Neutral P01583 N125D Neutral Neutral P01583 R85Q Neutral Neutral P01583 D176H Neutral Neutral P01583 D138N Neutral Disease Q14129 A117V Neutral Neutral P57727 G111S Neutral Neutral P57727 D173N Neutral Neutral P57727 I253V Neutral Neutral P57727 A426T Neutral Disease P57727 V53I Neutral Neutral Q9NRS4 R177Q Neutral Neutral P04198 R393S Disease Disease P01106 N11S Neutral Disease P01106 G160C Neutral Neutral P04198 R393H Disease Disease P01106 V170I Neutral Neutral P01106 A322V Neutral Neutral P04198 R394H Disease Disease Q9UQP3 T499M Neutral Neutral Q9UQP3 T941M Neutral Neutral Q9UQP3 W807R Neutral Neutral Q9UQP3 P930L Neutral Neutral Q9UQP3 D289N Neutral Neutral Q6UXB1 T66S Neutral Neutral Q5SW96 S202P Neutral Neutral Q5SW96 S202H Disease Neutral P98160 C1532Y Disease Disease O95428 A461V Neutral Neutral O95428 L1192V Neutral Neutral O95428 R896G Neutral Neutral O95428 N356H Neutral Neutral O95428 H628R Neutral Neutral O95428 Q723H Neutral Neutral O95428 S1260T Neutral Neutral O95428 S33G Neutral Neutral O95428 V443I Neutral Neutral O95428 T1201M Neutral Disease O95428 A191T Neutral Neutral O94827 F703S Disease Disease Q8TD35 G9W Neutral Neutral Q6WKZ4 M1185T Neutral Neutral P49639 H73R Neutral Neutral P49639 E189A Neutral Neutral O75325 L518V Neutral Neutral O75325 P7L Neutral Neutral P41182 H676Y Neutral Neutral P41182 A493T Neutral Disease Q8N7C7 F221L Neutral Neutral Q8IX29 R75Q Neutral Neutral Q8IX29 M254I Neutral Neutral Q8TF30 R345Q Neutral Neutral Q8TF30 R686H Neutral Neutral Q8TF30 Q340K Neutral Neutral Q8N567 P15A Neutral Neutral Q96LD8 T207A Neutral Neutral Q99490 N939D Disease Neutral Q99490 V947M Disease Neutral Q99490 E767V Disease Neutral Q99490 G507S Neutral Neutral Q99490 A651V Disease Neutral Q99490 V455A Disease Neutral Q99490 S1022P Disease Neutral Q99490 R518G Disease Neutral Q9NZT2 S577T Neutral Neutral P46087 L73S Neutral Neutral Q6P047 F15L Neutral Neutral P23526 D86N Neutral Disease P51955 C410Y Neutral Neutral P51955 N354S Neutral Neutral Q9BYF1 N638S Neutral Neutral Q9BYF1 K26R Neutral Neutral Q53FE4 E91K Neutral Neutral Q53FE4 G64E Neutral Neutral Q53FE4 S85P Neutral Neutral Q9H444 D129V Disease Disease Q9BY43 G153R Neutral Disease Q9H444 E161K Disease Disease O75791 L319F Neutral Neutral Q9H4I8 S46N Neutral Neutral Q9P2G1 L1016M Neutral Neutral Q8NEE6 D692G Neutral Neutral Q8NEE6 Y565C Neutral Disease Q8NEE6 M74I Neutral Neutral Q8NEE6 I535V Neutral Neutral Q8NEE6 G313A Neutral Disease Q9Y3A5 I87S Disease Disease Q9Y3A5 R169C Disease Disease Q9Y3A5 N8K Disease Disease Q9Y3A5 E44G Disease Disease Q9Y3A5 I212T Disease Disease Q9Y3A5 K67E Disease Disease Q9Y3A5 R126T Disease Disease Q3KQU3 R104W Neutral Neutral P33316 P100S Neutral Neutral Q0VF96 L1101V Neutral Neutral Q0VF96 M1270V Neutral Neutral Q0VF96 P380T Neutral Neutral Q0VF96 S459F Neutral Neutral Q0VF96 A511T Neutral Neutral Q6UWZ7 A239T Neutral Neutral Q93088 R239Q Neutral Neutral Q5U5R9 P19A Neutral Neutral P54802 R565Q Disease Disease P54802 Y92H Disease Disease P54802 G79C Disease Neutral P54802 H100R Neutral Disease P54802 G737R Neutral Neutral P54802 E705K Disease Disease P54802 R643C Disease Disease P54802 P358L Disease Neutral P54802 E452K Disease Neutral P54802 F48L Disease Disease P54802 L561R Disease Disease P54802 L682R Disease Disease P54802 P115S Disease Disease P54802 Y140C Disease Disease P54802 R565W Disease Disease P54802 R643H Disease Disease P54802 F314L Disease Disease P54802 R482W Disease Disease P54802 R565P Disease Disease P54802 C277F Disease Disease P54802 G292R Disease Disease P54802 R674H Disease Disease P54802 P521L Disease Disease P54802 A664V Disease Neutral P54802 L280P Disease Disease P54802 E153K Disease Disease P54802 P243L Disease Disease Q9UHC1 T942I Neutral Neutral Q9UHC1 D826N Neutral Neutral Q9UHC1 G1163D Neutral Neutral Q9UHC1 L492V Neutral Neutral Q9UHC1 S817G Disease Neutral Q9UHC1 V723I Neutral Neutral Q9UHC1 K231Q Neutral Neutral Q9UHC1 N1007S Disease Neutral Q9UHC1 D1105E Neutral Neutral Q9UHC1 E1451K Disease Neutral Q9UHC1 F120S Neutral Neutral Q9UHC1 R600Q Neutral Neutral Q9UHC1 S966P Neutral Neutral Q9UHC1 T606P Neutral Disease Q9UHC1 P844L Neutral Neutral Q9UHC1 V420I Neutral Neutral Q9UHC1 D1073N Neutral Neutral Q9UHC1 G1319R Neutral Neutral Q9UHC1 S845G Neutral Neutral Q9UHC1 A1394T Disease Disease Q9UHC1 H494R Neutral Neutral Q9UHC1 Y720C Neutral Neutral Q9UHC1 R93G Neutral Disease Q9UHC1 V741F Neutral Neutral Q9UHC1 N499S Disease Neutral Q9UHC1 E624Q Disease Neutral Q9UHC1 R797H Neutral Neutral Q9UHC1 G981S Disease Neutral Q9UHC1 R647C Disease Neutral Q9UHC1 Q24E Disease Disease Q9BQL6 A534T Neutral Neutral Q9BQL6 R526K Neutral Neutral P51690 R111P Disease Disease P51690 G245R Disease Disease P51690 T481M Disease Disease P08842 W372R Disease Disease P08842 S341L Disease Disease P08842 W372S Disease Disease P51690 P578S Disease Disease P51690 C492Y Disease Disease P08842 Q560P Disease Disease P51690 G117R Disease Disease P08842 C446Y Disease Disease P51690 R183H Neutral Neutral P51690 R12S Disease Disease P51690 G424S Neutral Disease P08842 G380R Disease Disease P51690 I80N Disease Disease P08842 H444R Disease Disease P51690 G137V Disease Disease P46778 F15S Neutral Disease Q9Y5Y7 V315M Neutral Neutral Q9Y5Y7 W116R Neutral Disease Q9Y5Y7 T214I Neutral Neutral Q5S007 R1441G Disease Disease Q5S007 I1122V Disease Neutral Q5S007 G2385R Disease Neutral Q5S007 S1096C Disease Disease Q5S007 R1441C Disease Disease Q5S007 R793M Disease Neutral Q5S007 S1228T Disease Neutral Q5S007 P1542S Disease Neutral Q5S007 G2019S Disease Disease Q5S007 I1371V Disease Neutral Q5S007 M1869T Disease Neutral Q5S007 I2012T Disease Neutral Q5S007 R1941H Disease Disease Q5S007 R1514Q Disease Neutral Q5S007 I2020T Disease Neutral Q5S007 Q930R Disease Neutral Q5S007 Y1699C Disease Disease Q5S007 T2356I Disease Neutral Q5S007 V1598E Disease Disease Q5S007 R1441H Disease Disease Q9NRH3 M413V Neutral Disease Q3ZCM7 L345F Neutral Disease Q71U36 S419L Disease Disease Q13748 V75L Neutral Disease Q9H4B7 Q43P Neutral Disease P04350 A365V Neutral Neutral Q71U36 P263T Disease Disease Q71U36 L286F Disease Disease Q13748 V440M Neutral Neutral Q71U36 R402H Disease Disease Q9H4B7 Q43H Neutral Disease Q71U36 I188L Disease Disease A6NHL2 R250W Neutral Disease Q71U36 R402C Disease Disease Q9NY65 Q301R Neutral Disease A6NHL2 Q135H Neutral Neutral Q71U36 E447K Neutral Neutral Q71U36 R264C Disease Disease Q8WWH5 R167K Neutral Neutral Q96GR4 P69S Neutral Disease Q96GR4 Q172L Neutral Disease Q9NQE9 G36A Neutral Neutral O15205 S160C Neutral Disease O15205 C162F Neutral Disease O15205 L51S Neutral Disease O15205 S95P Neutral Disease O15205 I68T Neutral Disease O15205 A99G Neutral Neutral Q9NRM0 R294H Neutral Neutral Q9NRM0 V282I Neutral Neutral Q9NRM0 R25G Neutral Neutral Q9NRM0 L350P Neutral Disease O43272 L357P Disease Disease P48507 I209M Neutral Neutral O94927 P213L Neutral Neutral O94927 A277D Neutral Neutral Q9H3S5 F365L Neutral Neutral Q8NBR9 P22T Neutral Neutral Q2M3A8 G142V Neutral Neutral Q2M3A8 S135F Neutral Neutral Q2M3A8 E6A Neutral Neutral Q8WWF5 R163H Neutral Disease Q8WWF5 R78Q Neutral Neutral Q8WWF5 D192N Neutral Neutral Q8WWF5 A157S Neutral Neutral Q8WWF5 R163C Neutral Disease Q8WWF5 V100I Neutral Neutral Q8WWF5 P37S Neutral Neutral Q8WWF5 V159A Neutral Neutral Q6UXH9 A305T Neutral Neutral Q9Y2U8 D260Y Neutral Neutral Q8N2S1 T1141M Neutral Neutral Q8N2S1 P679A Neutral Neutral Q8N2S1 T787A Neutral Neutral Q8N2S1 V194I Neutral Neutral Q8N2S1 T820A Neutral Neutral Q8N2S1 R635G Neutral Disease Q8TCZ9 M997K Disease Neutral Q8TCZ9 D2761Y Disease Disease Q8TCZ9 D703N Disease Disease Q8TCZ9 G223S Disease Neutral Q8TCZ9 V1789L Disease Neutral Q8TCZ9 P3783S Disease Neutral Q8TCZ9 Y2863C Disease Neutral Q8TCZ9 T36M Disease Neutral Q8TCZ9 I3468V Disease Neutral Q8TCZ9 P1486L Disease Disease Q8TCZ9 S1867N Disease Neutral Q8TCZ9 N3175D Disease Disease Q8TCZ9 C1249W Disease Disease Q8TCZ9 I307T Disease Disease Q8TCZ9 C2422G Disease Disease Q8TCZ9 V2032L Disease Neutral Q8TCZ9 G326V Disease Disease Q8TCZ9 A17V Disease Neutral Q8TCZ9 R1624W Disease Neutral Q8TCZ9 F253L Disease Neutral Q8TCZ9 I473S Disease Disease Q8TCZ9 V3036G Disease Neutral Q8TCZ9 G1123S Disease Neutral Q8TCZ9 I3167L Disease Neutral Q8TCZ9 R496P Disease Neutral Q8TCZ9 I2957T Disease Disease Q8TCZ9 H3124Y Disease Disease Q8TCZ9 D1942G Disease Neutral Q8TCZ9 I3553T Disease Neutral Q8TCZ9 F372L Disease Neutral Q8TCZ9 P805L Disease Neutral Q8TCZ9 R3482C Disease Disease Q8TCZ9 G1971D Disease Disease Q8TCZ9 I3177T Disease Neutral Q8TCZ9 C1472Y Disease Disease Q8TCZ9 D3293V Disease Neutral Q8TCZ9 T1781I Disease Neutral Q8TCZ9 Y486H Disease Neutral Q8TCZ9 I3081V Disease Neutral Q8TCZ9 L2772P Disease Disease Q8TCZ9 I1998T Disease Disease Q8TCZ9 P1389T Disease Disease Q8TCZ9 D2962G Disease Disease Q8TCZ9 S2861G Disease Neutral Q8TCZ9 I2331K Disease Disease Q8TCZ9 A1030E Disease Disease Q8TCZ9 V1741M Disease Neutral Q8TCZ9 C2688F Disease Neutral Q8TCZ9 W656C Disease Disease Q8TCZ9 C3622Y Disease Disease Q8TCZ9 G1122S Disease Disease Q8TCZ9 P739L Disease Neutral Q8TCZ9 I757L Disease Neutral Q8TCZ9 S1664F Disease Neutral Q8TCZ9 V3471G Disease Neutral Q8TCZ9 C3346R Disease Disease Q8TCZ9 I2303F Disease Neutral Q8TCZ9 I222V Disease Neutral Q8TCZ9 E3502V Disease Disease Q8TCZ9 S1833L Disease Neutral Q8TCZ9 S2983L Disease Neutral Q8TCZ9 L2134P Disease Disease Q8TCZ9 Q1917R Disease Neutral Q8TCZ9 T899P Disease Neutral Q8TCZ9 Y1838C Disease Disease Q8TCZ9 T2641A Disease Neutral Q8TCZ9 E1995G Disease Neutral Q8TCZ9 R760H Disease Neutral Q8TCZ9 E3529Q Disease Neutral Q8TCZ9 S3018F Disease Disease Q8TCZ9 L1407R Disease Disease Q8TCZ9 S1584I Disease Disease Q8TCZ9 N3175S Disease Disease Q53S58 D267E Neutral Neutral Q53S58 G29A Neutral Neutral Q53S58 I32V Neutral Neutral Q9NUU6 F319L Neutral Neutral Q9NWS6 H239R Neutral Neutral Q9NWS6 L129V Neutral Neutral Q8TBE0 Q298K Neutral Neutral Q8TBE0 D182H Neutral Neutral Q8TBE0 E26G Neutral Neutral Q13825 A240V Disease Disease Q969J3 S41C Neutral Neutral Q969J3 D191N Neutral Neutral Q8TAM1 L376F Neutral Neutral Q8TAM1 L414S Disease Neutral Q8TAM1 S311A Disease Neutral Q8TAM1 G677V Disease Disease Q8TAM1 Y613C Disease Disease Q8TAM1 R34P Disease Disease Q8TAM1 Y197C Disease Neutral Q8TAM1 Y613H Disease Neutral Q8TAM1 L170S Disease Disease Q8TAM1 S329L Disease Neutral Q8TAM1 V240G Disease Neutral Q8TAM1 C91W Disease Disease Q8TAM1 L308F Disease Neutral Q8TAM1 P363L Disease Neutral Q8TAM1 R49W Disease Disease Q8TAM1 C195W Disease Disease Q8TAM1 K579R Disease Neutral Q8TAM1 T689P Disease Neutral Q9BQF6 Q546H Neutral Neutral Q9BQF6 K79Q Neutral Neutral Q96DS6 V47F Neutral Disease Q58WW2 V547A Neutral Neutral Q16082 G111S Neutral Disease P55822 A188V Neutral Neutral P46063 V102I Neutral Neutral P46063 K487T Neutral Neutral P46063 D495H Neutral Neutral Q96JM3 P604R Neutral Neutral Q96JM3 L568V Neutral Neutral Q9HCP6 M403V Neutral Neutral Q8TBC3 Q507L Neutral Disease Q9BY15 E127Q Neutral Neutral Q96BN2 R198Q Neutral Neutral Q8NFR9 P402S Neutral Neutral Q8NFR9 S417T Neutral Neutral Q8NFR9 Y219C Neutral Neutral A1L4L8 C11S Neutral Neutral Q9NYJ7 G385D Disease Disease Q9NYJ7 L218P Neutral Disease P13498 P156Q Disease Neutral P13498 H72Y Neutral Neutral P13498 S118R Disease Disease P13498 H94R Disease Disease P13498 R90Q Disease Disease P13498 G24R Disease Disease Q9NUN5 D469E Neutral Neutral Q9NUN5 T144A Neutral Disease Q9NUN5 I395V Neutral Neutral P37287 G239R Disease Disease P37287 G48V Disease Disease P37287 R19W Disease Neutral P37287 D40H Disease Disease P37287 H128R Disease Disease P37287 N297D Disease Neutral P37287 G48A Disease Disease P37287 S155F Disease Disease P37287 G48D Disease Disease Q6IQ23 V693I Neutral Neutral Q6IQ23 A248V Neutral Neutral Q6IQ23 L241I Neutral Neutral Q6IQ23 Q279R Neutral Neutral Q6P087 A173P Neutral Neutral Q6P087 D26H Neutral Neutral P14410 L620P Disease Disease P14410 C1229Y Disease Disease P14410 Q1098P Disease Disease P14410 T694P Disease Disease P14410 S594P Disease Disease P14410 L341P Disease Disease P14410 G1073D Disease Disease P14410 Q117R Disease Neutral P14410 V15F Neutral Neutral P14410 T1802S Neutral Neutral P14410 F1745C Disease Disease P14410 V577G Disease Neutral P14410 R1367G Disease Disease P14410 I1523M Neutral Disease P14410 A231T Neutral Neutral P01877 V335A Neutral Neutral P01877 V326I Neutral Neutral P01877 F279Y Neutral Disease P01877 D296E Neutral Neutral P01877 P93S Neutral Neutral P01877 P102R Neutral Neutral P01876 E176D Neutral Neutral P16050 V239M Neutral Neutral P16050 N103K Neutral Neutral Q9BYJ1 V500F Disease Disease P18054 Q261R Neutral Neutral P16050 R205Q Neutral Neutral P16050 A461P Neutral Disease O75342 H578Q Disease Disease P16050 D90H Neutral Neutral O15296 R656Q Neutral Neutral O15296 I676V Neutral Neutral O75342 L426P Disease Disease O15296 I647V Neutral Neutral P09917 E254K Neutral Neutral P18054 N322S Neutral Neutral P18054 A298T Neutral Disease P16050 G102V Neutral Disease P16050 T560M Neutral Neutral Q9BYJ1 R396S Disease Disease P18054 E259K Neutral Neutral P18054 R430H Neutral Disease Q9UKW4 T298S Neutral Neutral Q9UKW4 Q618H Neutral Neutral Q9GZL7 E286G Neutral Neutral Q9GZL7 Y89C Neutral Neutral Q9GZL7 M72V Neutral Neutral P23327 S96A Neutral Neutral P23327 S43N Neutral Neutral Q9UH90 V87A Neutral Neutral Q9UH99 G671S Neutral Disease Q8N3J2 K310Q Neutral Neutral Q8N3J2 L468V Neutral Neutral Q8N3J2 L163F Neutral Neutral P16499 N216S Neutral Neutral P35913 Y212H Neutral Disease P16499 S344R Disease Disease P16499 K827Q Neutral Neutral P35913 E166K Neutral Neutral P51160 E834G Neutral Neutral P35913 L527P Disease Disease P16499 V277A Neutral Disease P51160 D157E Neutral Disease P16499 Q569K Disease Disease P35913 I535N Disease Disease P35913 L854R Disease Disease P16499 P293L Neutral Neutral P35913 H258N Disease Disease P51160 K822N Neutral Disease P16499 V391M Neutral Disease P16499 R102S Disease Disease P35913 R552Q Disease Disease P16499 S573P Disease Disease P35913 G576D Disease Disease P35913 L699R Disease Disease P16499 R102H Disease Disease P35913 H557Y Disease Disease P35913 L228H Disease Disease P16499 G850V Neutral Neutral P35913 L228I Neutral Neutral P35913 R74C Disease Neutral P35913 Y219H Disease Neutral Q8N371 E302D Neutral Neutral A6NGQ2 A92V Neutral Neutral A6NGQ2 A18T Neutral Neutral Q8IY47 Q166K Neutral Neutral Q8IY47 E189G Neutral Neutral Q8IY47 T193P Neutral Disease Q8IY47 L534I Neutral Neutral Q8IY47 P254R Neutral Disease Q8IY47 P301R Neutral Disease Q8IY47 S594Y Neutral Neutral Q9P109 V321I Neutral Neutral Q9P109 P439S Neutral Neutral P16930 G337S Disease Disease P16930 P261L Disease Disease P16930 V166G Disease Disease P16930 G207D Disease Disease P16930 F62C Disease Disease P16930 N16I Disease Disease P16930 A134D Disease Disease P16930 D233V Disease Disease P16930 Q64H Disease Disease P16930 G158D Disease Disease P16930 C193R Disease Disease P16930 P249T Disease Disease P16930 R341W Disease Disease P16930 P342L Disease Disease P16930 F405H Disease Disease P16930 G369V Disease Disease P16930 R381G Disease Disease P16930 W234G Disease Disease P16930 T294P Disease Disease Q9Y4C4 L163V Neutral Neutral Q9Y4C4 P892L Neutral Neutral P27635 N202S Neutral Disease P07360 H124N Neutral Neutral P07360 R69Q Neutral Neutral P07911 C248W Disease Disease P07911 C300G Disease Disease P07911 C126R Disease Disease P07911 C148Y Disease Disease P07911 C217R Disease Disease P07911 C223Y Disease Disease P07911 C77Y Disease Disease P07911 N128S Disease Disease P07911 C255Y Disease Disease P07911 T225K Disease Disease P07911 G103C Disease Disease Q6DJT9 P458T Neutral Neutral Q05C16 M206V Neutral Neutral Q05C16 M137V Neutral Neutral Q05C16 T282A Neutral Neutral Q05C16 K281R Neutral Neutral O75084 G196E Neutral Neutral O75084 G24S Neutral Neutral O75084 A487V Neutral Disease Q9Y3T6 V347M Neutral Neutral Q9Y3T6 R185K Neutral Neutral Q9Y3T6 L403R Neutral Disease Q9Y3T6 A136T Neutral Neutral Q96P09 Y196H Neutral Neutral P19622 L121F Neutral Neutral Q96JP9 H53Q Neutral Neutral Q96JP9 P532A Neutral Neutral Q96JP9 A243V Neutral Neutral Q96JP9 A212T Neutral Neutral Q9BZ95 R383P Neutral Disease Q05BV3 I269V Neutral Neutral P01160 V32M Neutral Neutral P09758 D216E Neutral Neutral P09758 D173A Neutral Neutral P16422 M115T Neutral Neutral O75582 P574L Neutral Neutral P51812 R114W Disease Disease P51812 H127Q Disease Disease Q15418 K335T Neutral Neutral P51812 R729Q Disease Disease O75582 Y599C Neutral Disease P51812 G75V Disease Disease P51812 A225V Disease Disease P51812 S227A Disease Neutral P51812 G431D Disease Disease O75582 D554N Neutral Neutral P51812 D154Y Disease Disease P51812 V82F Disease Disease P35443 A420V Neutral Neutral P35443 A387P Neutral Neutral P35443 L55Q Neutral Disease P35443 V646I Neutral Neutral Q13287 S16L Neutral Neutral Q969V4 V332I Neutral Neutral Q9UIF3 R46C Neutral Disease Q969V4 I146V Neutral Neutral Q969V4 R254C Neutral Disease A6BM72 H242R Neutral Neutral Q5VY80 R26G Neutral Neutral Q5VY80 L106R Neutral Disease Q5VY80 M85T Neutral Neutral O95278 G279S Disease Disease O95278 R91P Disease Disease O95278 R108C Disease Disease O95278 F84L Disease Neutral O95278 E28K Disease Neutral O95278 P301L Disease Disease O95278 T187A Disease Neutral O95278 Y294N Disease Disease O95278 R171H Disease Disease O95278 W32G Disease Disease O95278 Q293L Disease Disease O95278 S25P Disease Neutral O95278 G240S Disease Neutral O95278 E114D Neutral Neutral O95278 T194I Disease Neutral O95278 F88L Disease Disease O15204 M121T Neutral Neutral O15204 N444S Neutral Neutral P28067 H162Q Neutral Neutral P28067 R210C Neutral Disease P28067 G181A Neutral Neutral P28067 R210H Neutral Disease P28067 V166I Neutral Neutral P28067 D163H Neutral Neutral Q9UGN5 D235G Neutral Neutral Q9UGN5 N168S Neutral Neutral Q9UGN5 I285V Neutral Neutral Q9UGN5 R296Q Neutral Neutral Q9UGN5 S161N Neutral Neutral Q96T54 M253L Neutral Neutral Q96T54 S21G Neutral Neutral Q96T54 R296Q Neutral Neutral Q6ZUX7 I102V Neutral Neutral Q9H9F9 I483V Neutral Neutral Q9H9F9 P580L Neutral Neutral Q9H9F9 R298L Neutral Neutral O95475 T165A Disease Disease O95475 H141N Neutral Neutral P19784 E188A Neutral Neutral Q9UHV2 T31A Neutral Neutral A6H8M9 R5K Neutral Neutral Q16619 A92T Neutral Neutral Q8IZ20 H189N Neutral Neutral Q8IV48 L16P Neutral Neutral Q86US8 H1233R Neutral Neutral Q86US8 K294Q Neutral Neutral Q86US8 A972T Neutral Neutral Q86US8 R291P Neutral Neutral Q86US8 N341T Neutral Neutral Q8N2A8 R108H Neutral Neutral Q8N2A8 L42P Neutral Disease Q8NCL9 C30R Neutral Neutral Q8NCL9 R261C Neutral Disease Q8NCL9 Y80H Neutral Neutral Q01804 A194G Neutral Neutral Q01804 A216T Neutral Neutral O60762 S248P Disease Disease O60762 R92G Disease Disease O75762 E179K Neutral Neutral O75762 C3R Neutral Neutral O75762 N186K Neutral Neutral O75762 H1018R Neutral Neutral Q9Y2I9 V752I Neutral Neutral Q9Y2I9 Q296H Neutral Disease P24821 Q2008E Neutral Neutral P24821 V605I Neutral Neutral P24821 Q539R Neutral Disease P24821 Q680R Neutral Neutral P24821 A1781T Neutral Disease Q15111 W684C Neutral Disease Q9UPR0 P809H Neutral Disease Q15111 D445N Neutral Disease Q9UPR0 Q211R Neutral Neutral Q15111 P454S Neutral Disease Q9UPR0 V635M Neutral Neutral Q9UPR0 A742V Neutral Disease Q15111 S937N Neutral Neutral Q15111 V667I Neutral Neutral Q9UPR0 H890R Neutral Neutral Q15111 S546F Neutral Neutral Q8NA57 R322H Neutral Neutral Q8NA57 Q306R Neutral Neutral Q7Z4H3 R64C Neutral Disease Q9UKM9 G251S Neutral Neutral Q9UKM9 Q215R Neutral Neutral Q68D10 K617R Neutral Neutral Q68D10 S317F Neutral Neutral Q68D10 R447Q Neutral Neutral P48047 K98R Neutral Neutral Q66I50 R13S Neutral Neutral Q66I50 R16P Neutral Disease Q66I50 Y9C Neutral Neutral Q8IYU8 Q260L Neutral Disease P46663 A250V Neutral Neutral Q9Y6I8 V204I Neutral Neutral O95436 V45A Neutral Neutral O95436 G106R Disease Disease O95436 G634D Neutral Disease Q99440 N15K Neutral Disease Q9NP31 N52S Neutral Neutral Q9UKK3 G1280R Neutral Neutral Q9UKK3 G1265A Neutral Neutral Q9Y252 N48S Neutral Neutral P60372 R62C Neutral Neutral P60372 I159V Neutral Neutral Q8WXK8 N993K Neutral Neutral Q8WXK8 H1116Y Neutral Neutral P19957 T34P Neutral Neutral Q8NFG4 R320Q Disease Neutral Q8NFG4 S79W Disease Neutral Q8NFG4 A445T Disease Neutral Q8NFG4 A238V Disease Neutral Q8NFG4 R392G Disease Neutral Q8NFG4 A444S Disease Neutral Q7RTY1 T258K Neutral Neutral Q7RTY1 D461E Neutral Neutral Q7Z2E3 V277G Disease Disease Q7Z2E3 L237P Disease Disease Q7Z2E3 H215R Disease Disease Q7Z2E3 A212V Disease Disease Q7Z2E3 R213H Disease Disease Q7Z2E3 D281G Disease Disease Q7Z2E3 W293R Disease Disease Q7Z2E3 P220L Disease Disease Q7Z2E3 K211Q Disease Disease Q8TD26 H2161Q Neutral Neutral Q2NL82 H750Q Neutral Neutral Q2NL82 K727Q Neutral Disease Q2NL82 S386G Neutral Neutral Q2NL82 N719S Neutral Neutral P17028 G331W Neutral Neutral P17028 N220S Neutral Neutral Q9UGU0 S722G Neutral Neutral Q9UGU0 M1165I Neutral Neutral Q9UGU0 T485N Neutral Neutral Q9UGU0 S1325N Neutral Neutral Q9Y5T4 R35G Neutral Neutral Q68D51 D2E Neutral Neutral Q68D51 D170G Neutral Neutral P13945 T265M Neutral Neutral P13945 W64R Neutral Neutral P13945 R353C Neutral Disease P13945 E249K Neutral Neutral Q9HBU1 T19A Neutral Neutral Q3KNW5 I114V Neutral Neutral Q3KNW5 S6F Neutral Neutral Q9Y2A9 H328R Neutral Neutral Q03591 Y157H Neutral Neutral Q03591 Q175E Neutral Neutral Q03591 V159L Neutral Neutral O14813 A72V Disease Neutral Q6IWH7 V67I Neutral Neutral Q9NSC2 G1265E Neutral Neutral Q9NSC2 S159G Neutral Neutral Q6ZU52 S61R Neutral Neutral P25929 K374T Neutral Neutral O43837 A3V Neutral Neutral Q96KN8 A93P Neutral Neutral P13073 Y38F Neutral Neutral Q7Z4T8 R124C Neutral Neutral Q92922 P1075H Neutral Neutral P43146 M1017V Neutral Neutral P43146 P1375H Disease Neutral P43146 R201G Neutral Disease P43146 M168T Disease Disease Q92859 P534L Neutral Neutral Q6PGQ7 S210L Neutral Neutral Q6PGQ7 S308F Neutral Neutral Q9BYX4 H843R Neutral Neutral Q9BYX4 H460R Neutral Neutral Q9BYX4 A946T Neutral Neutral Q9UKE5 G910E Neutral Neutral O95819 S712T Neutral Neutral Q9UKE5 A999T Neutral Neutral Q9UKE5 K778E Neutral Neutral Q8N4C8 A514T Neutral Neutral Q8N4C8 I1200V Neutral Neutral Q5HY92 S96L Neutral Neutral Q5HY92 K565R Neutral Disease Q5HY92 R448C Neutral Disease P25942 P227A Neutral Neutral P25942 S35G Disease Neutral P25942 C26Q Disease Disease P25942 C83R Disease Disease P25942 S124L Neutral Neutral P25942 S39T Disease Neutral Q5RHP9 R555H Neutral Neutral Q5RHP9 I636V Neutral Neutral Q5RHP9 H691R Neutral Neutral Q5RHP9 P264A Neutral Neutral Q5RHP9 L1056V Neutral Neutral Q5RHP9 V1528M Neutral Neutral P23470 Q639R Neutral Neutral P23470 G574S Neutral Neutral Q9P0W8 V74M Neutral Neutral Q6PB30 Y28F Neutral Neutral O14521 H50R Neutral Neutral O14521 D92Y Disease Disease O14521 P81L Disease Disease O14521 G12S Neutral Neutral O14521 Y114C Disease Disease O14521 H102L Disease Disease O14521 L139P Disease Disease Q6UX04 P256A Neutral Neutral O95073 R226K Neutral Neutral Q0IIN9 L84I Neutral Neutral P00395 T10A Neutral Disease P00395 G224A Neutral Disease P00395 L196I Disease Neutral P00395 F235S Neutral Disease P00395 M273T Disease Disease P00395 S142F Disease Disease P00395 F305L Neutral Neutral P00395 I280T Disease Disease P00395 F94C Neutral Disease P00395 T415A Neutral Neutral P00395 V155L Neutral Neutral Q8TC41 V89I Neutral Neutral Q02318 R395S Disease Disease Q02318 R479C Disease Neutral Q02318 G145E Disease Disease Q02318 R474W Disease Disease Q02318 R474Q Disease Disease Q02318 R405Q Disease Disease Q02318 R395C Disease Disease O15528 V166L Neutral Disease Q8NBS3 N150S Neutral Neutral Q8NBS3 R869C Disease Disease Q8NBS3 S213P Disease Neutral Q8NBS3 M483T Neutral Disease Q8NBS3 R869H Disease Disease Q8NBS3 M856V Disease Disease Q8NBS3 R488K Disease Disease Q8NBS3 R755Q Disease Disease Q8NBS3 T833M Disease Disease Q8NBS3 S489L Disease Disease Q8NBS3 Q408H Neutral Neutral Q8NBS3 M848I Neutral Neutral Q8NBS3 R804H Disease Disease Q8NBS3 K409N Neutral Disease Q8NBS3 T708A Neutral Neutral Q8NBS3 A160T Neutral Neutral Q8NBS3 G464D Disease Disease Q8NBS3 V824M Disease Disease Q8NBS3 L843P Disease Disease P32245 V103I Neutral Neutral P32245 G181D Neutral Disease P32245 S127L Neutral Neutral P32245 T112M Neutral Neutral P32245 P78L Neutral Disease P32245 G252S Neutral Disease P32245 I251L Neutral Neutral P32245 R165Q Neutral Disease P32245 I226T Neutral Disease P32245 I317T Neutral Neutral P32245 D37V Neutral Disease Q68CJ6 R328Q Neutral Neutral Q68CJ6 S474N Neutral Neutral Q68CJ6 P23R Neutral Neutral Q68CJ6 S180G Neutral Neutral O75146 V782M Neutral Neutral P48167 G251D Disease Disease Q8IXA5 H100R Neutral Neutral Q8IXA5 C80Y Neutral Neutral Q53HC5 V542M Neutral Disease Q96NJ5 D146G Neutral Neutral Q96NJ5 N129S Neutral Neutral P58418 M120K Disease Neutral P58418 N48K Disease Disease P58418 L150P Disease Disease Q9Y6Y8 K644E Neutral Neutral Q9UMR3 I152M Disease Disease O75443 L1820F Disease Disease O75443 C1619S Disease Disease O75443 G1824D Disease Disease O75443 C1057S Disease Disease P30988 P463L Neutral Neutral P53396 E175D Neutral Neutral P23280 M68L Neutral Neutral P23280 Q37L Neutral Neutral P22748 R14W Disease Disease P22748 R219S Disease Disease P23280 S90G Neutral Neutral P23280 T55M Neutral Neutral P23280 G70A Neutral Disease O43307 G55A Disease Disease Q9BY49 F297L Neutral Neutral Q9BY49 E149K Neutral Disease P20936 C540Y Disease Disease P20936 I401V Disease Neutral P20936 R398L Disease Disease P20936 K400E Disease Neutral Q7Z3T8 T192I Neutral Neutral Q7Z3T8 T598I Neutral Neutral Q7Z3T8 G1055S Neutral Neutral Q9UJ78 C137F Neutral Neutral Q9UJ78 I125V Neutral Neutral O15255 S152W Neutral Neutral P09001 M261T Neutral Disease Q9UHF7 R908Q Disease Disease Q9UHF7 R952C Disease Neutral Q9UHF7 S654L Neutral Neutral Q9UHF7 R908P Disease Disease Q9UHF7 V894D Disease Disease Q9UHF7 A919T Disease Disease Q9UHF7 R952H Disease Neutral Q9UHF7 T901P Disease Neutral Q9NYU1 A323T Neutral Neutral Q9NYU1 M994L Neutral Neutral Q9NYU1 A328S Neutral Neutral Q96CX3 M17V Neutral Neutral Q13007 V131L Neutral Neutral Q13007 Y124H Neutral Neutral Q13007 H125R Neutral Neutral Q14002 F120I Neutral Neutral P04839 H222Y Disease Disease P04839 G389A Disease Disease P04839 C244Y Disease Disease P04839 P339H Disease Disease P04839 H209Q Disease Disease P04839 R54M Disease Disease P04839 A55D Disease Disease P04839 A57E Disease Disease P04839 D500G Disease Disease P04839 A224G Disease Neutral P04839 M405R Disease Disease P04839 E309K Disease Disease P04839 C244R Disease Disease P04839 H209Y Disease Disease P04839 W516R Disease Disease P04839 G389E Disease Disease P04839 C59R Disease Disease P04839 W453R Disease Disease P04839 L420P Disease Disease P04839 G408E Disease Disease P04839 H119R Disease Disease P04839 P304R Disease Disease P04839 G364R Neutral Neutral P04839 G20R Disease Disease P04839 W516C Disease Disease P04839 V534D Disease Disease P04839 H101R Disease Disease P04839 G408R Disease Disease P04839 H222N Disease Disease P04839 G322E Disease Neutral P04839 R356P Disease Disease P04839 G223L Disease Disease P04839 C244S Disease Disease P04839 H101Y Disease Disease P04839 R54S Disease Disease P04839 H209R Disease Disease P04839 D517E Neutral Neutral P04839 S333P Disease Disease P04839 S344F Disease Disease P04839 C537R Disease Disease P04839 P415H Disease Disease P04839 A156T Disease Neutral P04839 E225V Disease Disease P04839 H222R Disease Disease P04839 P415L Disease Disease P04839 H303N Disease Disease P04839 H338Y Disease Disease P04839 Y41D Disease Disease P04839 I325F Disease Disease P04839 S422P Disease Disease O95755 P50L Neutral Neutral O95755 N308D Neutral Disease Q6ZW49 M979V Neutral Neutral Q9BZE2 E460D Neutral Neutral Q9BZE2 A46S Neutral Neutral Q9BZE2 Y3D Neutral Neutral Q9NYK6 Q117R Neutral Neutral Q9NYK6 D136E Neutral Neutral Q9UJT1 M76T Neutral Disease Q9NS68 V405I Neutral Neutral Q9NS68 S31T Neutral Neutral Q9Y4D2 P889L Neutral Neutral Q6P093 A186S Neutral Neutral Q6P093 L343I Neutral Disease P22760 I281V Neutral Neutral P04179 E66V Neutral Disease P04179 I82T Neutral Neutral P04179 G76R Neutral Disease P04179 S10I Neutral Neutral P04179 R156W Neutral Disease P04179 A16V Neutral Neutral Q7Z6J4 Q32H Neutral Neutral O60225 E19Q Neutral Neutral O60220 C66W Disease Disease Q8NE62 E40A Neutral Disease Q9H2M9 T863A Neutral Neutral Q9H2M9 S1092T Neutral Neutral Q9H2M9 G1052C Disease Disease P39060 V1076I Neutral Neutral P39060 G111R Neutral Neutral P39060 P1121R Neutral Neutral P39060 Q49L Neutral Neutral Q53FZ2 K367N Neutral Neutral Q08AH1 I479V Neutral Neutral Q08AH3 S513L Neutral Neutral Q08AH3 A561T Neutral Neutral Q6NUN0 Q159H Neutral Neutral Q6NUN0 P352R Neutral Disease Q53FZ2 P308T Neutral Neutral Q08AH1 I515T Neutral Neutral Q6NUN0 T533M Neutral Neutral Q53FZ2 L100P Neutral Disease Q6NUN0 H360R Neutral Neutral P54219 V249I Neutral Neutral P54219 A101P Neutral Neutral P54219 L392V Neutral Disease P54219 S98T Neutral Neutral P54219 I202T Neutral Neutral P54219 F82C Neutral Neutral P54219 G140R Neutral Disease P54219 I136T Neutral Neutral P54219 F84S Neutral Neutral P54219 I164M Neutral Disease P54219 A74V Neutral Neutral P54219 T4P Neutral Neutral P04150 R477H Disease Disease P04150 R23K Neutral Neutral P04150 G679S Disease Disease P04150 L112F Neutral Neutral P04150 V729I Disease Neutral P04150 F65V Neutral Neutral P04150 D233N Neutral Neutral P04150 N363S Neutral Neutral P04150 D641V Disease Neutral P04150 F29L Neutral Neutral P04150 I559N Disease Neutral P04150 C421Y Disease Disease P04150 L753F Disease Neutral P04150 I747M Disease Neutral Q13402 E1327K Disease Disease Q13402 T1566M Disease Neutral Q13402 Y1719C Disease Neutral Q13402 C1666G Neutral Disease Q13402 G2187D Disease Disease Q13402 R302H Disease Disease Q13402 R1240Q Disease Disease Q13402 R1873W Disease Disease Q13402 T165M Disease Disease Q13402 A198T Disease Disease Q13402 G2137E Disease Disease Q13402 R756W Disease Disease Q13402 G519D Disease Disease Q13402 I134N Disease Disease Q13402 G2163S Disease Disease Q13402 E968D Disease Neutral Q13402 H133D Disease Disease Q13402 R244P Disease Disease Q13402 V597I Neutral Neutral Q13402 R853C Disease Disease Q13402 L1087P Disease Neutral Q13402 A1288P Disease Disease Q13402 L16S Disease Neutral Q13402 E1170K Disease Disease Q13402 R241C Disease Disease Q13402 T204A Disease Disease Q13402 R212H Disease Disease Q13402 A26E Disease Neutral Q13402 L1858P Disease Disease Q13402 P503L Disease Disease Q13402 F1992I Neutral Disease Q13402 D2142N Neutral Neutral Q13402 E450Q Disease Disease Q13402 N458I Disease Disease Q13402 R241S Disease Disease Q13402 G25R Disease Disease Q13402 L651P Disease Disease Q13402 I1954L Neutral Neutral Q13402 G214R Disease Disease Q13402 R1343S Disease Disease Q13402 R1743W Disease Neutral Q13402 M599I Disease Neutral Q13402 I205V Neutral Neutral Q13402 C1666S Neutral Disease Q13402 A826T Disease Neutral Q13402 K164R Disease Disease Q13402 R90P Disease Disease Q13402 G1740S Neutral Neutral Q13402 V67M Disease Disease Q13402 R212C Disease Disease Q13402 A457V Disease Disease Q13402 R1883Q Disease Disease Q13402 A397D Disease Disease Q13402 G955S Disease Neutral Q13402 G163R Disease Disease Q13402 R1602Q Disease Neutral Q13402 G722R Disease Disease Q13402 P1887L Disease Disease Q13402 A1628S Disease Neutral Q53QW1 E168K Neutral Neutral Q53QW1 S261P Neutral Neutral Q53QW1 Q79R Neutral Neutral Q53QW1 V11L Neutral Neutral Q9Y646 S138N Neutral Disease Q9P275 V271I Neutral Neutral Q9P275 K814N Neutral Neutral Q9P275 Q806R Neutral Neutral Q9P275 R775Q Neutral Neutral Q9P275 I489M Neutral Neutral Q9P275 R828C Neutral Neutral Q6ZUB1 D704E Neutral Neutral Q6ZUB1 D1202G Neutral Neutral Q6ZUB1 T335P Neutral Neutral Q6ZUB1 R1350H Neutral Neutral Q6ZUB1 D682E Neutral Neutral P43629 I75L Neutral Neutral P43629 S333C Neutral Neutral Q8N743 I168V Neutral Neutral P43629 L13F Neutral Neutral P43630 P40A Neutral Neutral P43629 S2L Neutral Disease P43630 E158D Neutral Disease P43629 I68V Neutral Neutral P43630 R166H Neutral Disease P43630 A228P Neutral Neutral P43629 G259R Neutral Disease P43629 M23V Neutral Neutral P43630 I252T Neutral Neutral P43630 L113V Neutral Disease Q5W0V3 L408I Neutral Neutral Q5W0V3 F631L Neutral Neutral Q0VG06 A817T Neutral Neutral Q0VG06 L660P Neutral Neutral Q8NCL8 C22G Neutral Neutral O00566 L425M Neutral Neutral O00566 E634K Neutral Neutral O00566 E229D Neutral Neutral Q9GZV9 P195S Neutral Neutral Q9GZV9 R179W Disease Neutral Q9GZV9 R179Q Disease Neutral Q9GZV9 R176Q Disease Neutral Q9GZV9 T239M Neutral Neutral Q9GZV9 S71G Disease Neutral Q6P531 R40W Neutral Neutral Q6P531 A58V Neutral Neutral Q14999 Q1246G Disease Neutral Q14999 Q813R Neutral Neutral Q14999 L1014R Disease Disease Q14999 H1464P Disease Neutral Q86XI6 G48E Neutral Neutral Q8N9V7 K796E Neutral Neutral Q8N9V7 P673A Neutral Neutral Q8N9V7 R43C Neutral Neutral Q8N9V7 Q1352R Neutral Neutral Q8N9V7 Q483R Neutral Neutral Q8N9V7 Q88P Neutral Neutral Q8N9V7 V196I Neutral Neutral O15499 R47C Neutral Neutral P08908 P16L Neutral Neutral P08908 P184L Neutral Neutral P08908 I28V Neutral Neutral P35462 S9G Neutral Neutral P08908 R220L Neutral Neutral P08908 G273D Neutral Disease P08908 G22S Neutral Neutral Q5VUM1 Q46R Neutral Neutral Q8N4P6 R483H Neutral Neutral Q8N4P6 S503A Neutral Neutral O43638 P292A Neutral Neutral Q9HCQ7 V121M Neutral Neutral Q9HCQ7 D42G Neutral Neutral Q9HCQ7 M32I Neutral Neutral Q12906 D50H Neutral Neutral Q12904 P79A Neutral Neutral Q12904 T104A Neutral Neutral Q9P2K2 K486E Neutral Neutral P08118 I25M Neutral Neutral P08118 V98L Neutral Neutral P08118 L17S Neutral Neutral P08118 E91G Neutral Neutral P08118 I87T Neutral Disease P08118 D80A Neutral Disease P08118 Q53R Neutral Neutral P08118 W52R Neutral Neutral P08118 D92G Neutral Neutral P62324 Q141E Neutral Neutral P62324 N139S Neutral Neutral Q15047 A824P Neutral Neutral Q15047 N236S Neutral Neutral Q15047 P506S Neutral Neutral Q15047 A824G Neutral Disease Q9H3J6 A134T Neutral Neutral Q9BT04 T400I Neutral Neutral Q9BT04 A34S Neutral Neutral Q9BT04 G175D Neutral Neutral Q9H2X0 M630L Neutral Neutral Q8NBB6 V28M Neutral Neutral Q9NY33 R678H Neutral Neutral Q9NY33 Q145H Neutral Neutral Q9NY33 R76H Neutral Neutral Q06787 I304N Disease Disease Q06787 A145S Neutral Neutral Q06787 R546H Neutral Neutral Q9HD23 P35S Neutral Neutral Q9UBY8 R24G Disease Disease Q9UBY8 A155V Neutral Neutral Q9UBY8 L16M Disease Neutral Q9UBY8 H92Y Neutral Neutral Q9UBY8 W263C Disease Disease Q9UBY8 T170M Disease Neutral Q9UBY8 R204C Disease Disease Q8IV77 V553E Neutral Neutral P42127 V13A Neutral Neutral P42127 Q61P Neutral Neutral Q96A40 C152Y Neutral Neutral Q6BDI9 D101N Neutral Disease Q6BDI9 E206D Neutral Neutral Q9GZX6 S158G Neutral Neutral Q86YE8 G166A Neutral Disease Q8IYX0 E69G Neutral Disease Q9H707 W242C Neutral Neutral Q08AN1 H451R Neutral Neutral P51814 D357E Neutral Neutral Q96N22 S226L Neutral Neutral Q9NYW8 G229E Neutral Disease Q8NDP4 L427S Neutral Neutral Q96LX8 T30S Neutral Neutral Q08ER8 H246L Neutral Neutral Q15928 K124E Neutral Disease Q68DY9 C182W Neutral Disease Q9UJL9 C13Y Neutral Neutral Q8TC21 T130K Neutral Neutral Q9HAH1 R137C Neutral Disease Q8NEK5 T73A Neutral Neutral Q9UJW8 A41V Neutral Neutral Q86Y25 F546L Neutral Neutral Q8N8J6 T129M Neutral Neutral Q9UK10 T679S Neutral Neutral Q96GE5 C595R Neutral Disease Q68DY9 M218L Neutral Neutral Q8NEM1 S132F Neutral Disease Q96PE6 E28K Neutral Disease Q9BS31 G352D Neutral Disease Q96ND8 F324I Neutral Neutral Q9UK13 P337A Neutral Neutral Q9HCX3 E367K Neutral Neutral Q2VY69 K546E Neutral Disease Q9BR84 T251N Neutral Neutral Q96PE6 I379V Neutral Neutral Q8NEM1 D330G Neutral Neutral Q03923 K60T Neutral Disease Q8N9F8 D166A Neutral Neutral Q96PE6 N157D Neutral Disease Q08ER8 R107Q Neutral Neutral Q6PF04 I135R Neutral Neutral Q86XN6 Q603E Neutral Neutral P17035 K465Q Neutral Disease Q03923 F270S Neutral Neutral Q6P9A1 S124P Neutral Disease Q14929 P59L Neutral Disease Q6PF04 D84N Neutral Neutral Q8TC21 V470G Neutral Neutral Q96RE9 Q336H Neutral Neutral Q6P9A1 T169M Neutral Neutral Q2M3X9 P412L Disease Neutral Q5HYK9 T540A Neutral Neutral Q9NZL3 K640E Neutral Disease A6NK53 S247P Neutral Neutral Q6ZMW2 R165H Neutral Disease Q6IV72 D166V Neutral Neutral Q02386 R255K Neutral Neutral Q7Z3V5 K593E Neutral Disease Q02386 T299A Neutral Neutral Q15937 T31I Neutral Neutral Q15928 K358N Neutral Neutral Q86Y25 E553K Neutral Neutral Q96N22 H15D Neutral Neutral Q96PE6 R7K Neutral Neutral Q9UIE0 D441E Neutral Neutral Q68DY1 N31D Neutral Neutral Q86XN6 S528G Neutral Neutral Q96PE6 L69M Neutral Neutral Q7Z340 N218S Neutral Neutral Q6ZMW2 R130P Neutral Disease Q9HCX3 L121P Neutral Neutral Q6ECI4 K254R Neutral Neutral Q15928 R349K Neutral Neutral Q8TAW3 A149V Neutral Neutral Q02386 R504K Neutral Neutral Q6V9R5 K205E Neutral Neutral Q8IYX0 H120R Neutral Disease P51508 S179N Disease Neutral Q6P280 V98L Neutral Disease Q15935 L20W Neutral Disease Q6ZNA1 N809S Neutral Neutral Q08ER8 M573V Neutral Neutral Q9BS31 A469T Neutral Neutral O75820 R221K Neutral Neutral Q02386 P303R Neutral Neutral Q15935 G460R Neutral Disease Q9UJW8 C272S Neutral Neutral Q8IYX0 C223S Neutral Neutral Q9NV72 R455C Neutral Neutral Q7Z398 I359T Neutral Neutral Q14590 H292P Neutral Neutral Q9UK13 R557G Neutral Neutral Q8IZC7 M121L Neutral Neutral Q9H0M5 L321V Neutral Neutral Q7Z340 R550W Neutral Disease Q86XN6 I168V Neutral Disease Q08ER8 V439D Neutral Neutral Q6ZN06 R231K Neutral Neutral Q86Y25 E250K Neutral Neutral Q9UK13 R256C Neutral Neutral Q7Z3V5 E252D Neutral Neutral Q6P9A1 T64A Neutral Neutral Q2M3X9 T343M Neutral Neutral Q5VIY5 G477R Neutral Neutral Q6P9A1 G262S Neutral Neutral P51814 P153L Disease Neutral Q9NZL3 H162L Neutral Neutral Q9UIE0 S310C Neutral Neutral Q0VGE8 L162S Neutral Neutral P17035 R179G Neutral Neutral Q8IVC4 T301A Neutral Neutral Q08ER8 P55A Neutral Neutral Q14929 R368C Neutral Neutral Q9Y3M9 V17I Neutral Disease Q9BUY5 A4V Neutral Neutral Q8N9Z0 P216R Neutral Neutral Q06732 R145C Neutral Neutral Q15937 R51G Neutral Disease P51508 I499V Neutral Neutral Q6ZN06 Y439F Neutral Neutral P51508 G117V Neutral Disease Q96C28 H94P Neutral Neutral P52736 S193T Neutral Neutral Q03936 Q492R Neutral Neutral Q9HBT8 Y90H Neutral Neutral Q8NEK5 S58A Neutral Neutral Q9Y2H8 C89R Neutral Disease Q5HYK9 K260R Neutral Neutral Q08ER8 E287V Neutral Disease Q14584 P519L Neutral Neutral P51508 S185L Neutral Neutral Q7Z3V5 L573H Neutral Neutral P17035 T524M Neutral Neutral Q49AA0 V113L Neutral Disease Q6ECI4 V23L Neutral Disease P17027 S28G Neutral Neutral Q96PQ6 Q19H Neutral Neutral Q5JVG2 G502D Neutral Disease Q8N8J6 R727K Neutral Neutral Q7Z3V5 Q189H Neutral Neutral Q68DY1 N68H Neutral Neutral Q9UK13 V165M Neutral Neutral Q6PF04 K93E Neutral Neutral P17097 G188R Neutral Neutral Q6P9A1 H110Q Neutral Neutral Q8NEP9 K515T Neutral Neutral Q0VGE8 N80I Neutral Neutral Q15935 P179S Neutral Neutral P51508 A3V Neutral Neutral Q14588 V16I Neutral Neutral P51508 N157S Neutral Neutral Q8IVC4 P142S Neutral Neutral P52736 G194E Neutral Disease Q9UK13 T519S Neutral Disease Q8NEM1 N525D Neutral Neutral Q6ZNA1 M219I Neutral Neutral Q03923 G184R Neutral Neutral Q9UIE0 F434Y Neutral Neutral Q16587 E117K Neutral Neutral P52737 Y107C Neutral Neutral Q6V9R5 F178L Neutral Neutral A6NK53 T531K Neutral Disease Q02386 A187T Neutral Neutral Q8N9K5 I188T Neutral Neutral Q8IYX0 Y212H Neutral Neutral Q8N8J6 T360I Neutral Neutral Q96GE5 G46V Neutral Disease Q96NG8 R69T Neutral Disease P51814 I167R Neutral Neutral Q9Y2H8 Q43R Neutral Disease Q86XN6 S122I Neutral Disease Q9UJW8 W89C Neutral Neutral Q9UK13 I179F Neutral Neutral Q5SXM1 K144E Neutral Neutral Q9NV72 I116T Neutral Neutral Q6ECI4 I418T Neutral Neutral Q9NV72 P4L Neutral Disease Q9UK10 Q50R Neutral Neutral Q5VIY5 H374R Neutral Disease Q400G9 R491H Neutral Neutral Q56P03 Q168E Neutral Neutral Q9BZE0 T492A Neutral Neutral P06280 M187V Disease Disease P06280 R112H Disease Disease P06280 I91T Disease Disease P06280 H46Y Disease Neutral P06280 R363H Disease Neutral P06280 C172R Disease Disease P06280 P259L Disease Disease P06280 G328R Disease Disease P06280 G128E Disease Disease P06280 R227Q Disease Disease P06280 D92Y Disease Disease P06280 C52S Disease Disease P06280 L89P Disease Disease P06280 P409A Disease Disease P06280 G183D Disease Disease P06280 W236L Disease Disease P06280 N298S Disease Disease P06280 R49L Disease Disease P06280 S148R Disease Disease P06280 C202Y Disease Disease P06280 C172Y Disease Disease P06280 A377D Disease Disease P06280 A156V Disease Disease P06280 F113L Disease Disease P06280 N263S Disease Disease P06280 R301Q Disease Disease P06280 Y134S Disease Disease P06280 L32P Disease Disease P06280 C56G Disease Disease P06280 W287G Disease Disease P06280 Y86C Disease Disease P06280 M267I Disease Disease P06280 E341K Disease Neutral P06280 M284T Disease Disease P06280 I242N Disease Disease P06280 R49S Disease Neutral P06280 D93G Disease Disease P06280 D266N Disease Disease P06280 L131P Disease Disease P06280 W162C Disease Disease P06280 R356W Disease Disease P06280 C56F Disease Disease P06280 G373D Disease Disease P06280 M296V Disease Disease P06280 W47G Disease Disease P06280 R342Q Disease Disease P06280 Q327K Disease Disease P06280 C223G Disease Neutral P06280 D266H Disease Disease P06280 G144V Disease Disease P06280 P259R Disease Disease P06280 D92H Disease Disease P06280 A288D Disease Disease P06280 P146S Disease Disease P06280 I219N Disease Disease P06280 P40S Disease Disease P06280 P40L Disease Disease P06280 G261D Disease Disease P06280 V269A Disease Disease P06280 N298K Disease Disease P06280 W226R Disease Disease P06280 Q279E Disease Neutral P06280 D244H Disease Disease P06280 Q280H Disease Neutral P06280 G85D Disease Disease P06280 Q279H Disease Disease P06280 S297F Disease Disease P06280 D266V Disease Disease P06280 I289F Disease Disease P06280 G163V Disease Disease P06280 G35R Disease Disease P06280 N272K Disease Disease P06280 Y216D Disease Disease P06280 C378Y Disease Disease P06280 G361R Disease Neutral P06280 L89R Disease Disease P06280 M72V Disease Neutral P06280 W162R Disease Disease P06280 C56Y Disease Disease P06280 C94Y Disease Disease P06280 C142R Disease Disease P06280 D244N Disease Neutral P06280 F113S Disease Disease P06280 R49P Disease Disease P06280 G138R Disease Disease P06280 T410A Disease Neutral P06280 S65T Disease Neutral P06280 Q321E Disease Disease P06280 P409T Disease Neutral P06280 N320Y Disease Disease P06280 D165V Disease Disease P06280 W287C Disease Disease P06280 E66Q Disease Disease P06280 N298H Disease Disease P06280 V316E Disease Disease P06280 S235C Disease Neutral P06280 A156T Disease Disease P06280 E59K Disease Neutral P06280 W340R Disease Disease P06280 G258R Disease Disease P06280 G373S Disease Disease P06280 E358K Disease Disease P06280 D170V Disease Disease P06280 D231N Disease Disease P06280 C142Y Disease Disease P06280 S148N Disease Disease P06280 L166V Disease Neutral P06280 N272S Disease Disease P06280 M42V Disease Disease P06280 C202W Disease Disease P06280 N224D Disease Disease P06280 N320K Disease Disease P06280 W95S Disease Disease P06280 C94S Disease Disease P06280 D264V Disease Disease P06280 G260A Disease Disease P06280 P205T Disease Disease P06280 D313Y Disease Disease P06280 A97V Disease Neutral P06280 R100K Disease Disease P06280 A143T Disease Disease P06280 M296I Disease Neutral P06280 H46R Disease Neutral P06280 A31V Disease Disease P06280 N34S Disease Disease P06280 C52R Disease Disease P06280 N224S Disease Disease P06280 A143P Disease Disease P06280 R100T Disease Disease P06280 W236C Disease Disease P06280 A230T Disease Neutral P06280 N215S Disease Neutral P06280 A20P Disease Disease P06280 G328A Disease Neutral P06280 P265R Disease Disease P06280 R112C Disease Disease P53634 G139R Disease Disease P53634 Y294H Disease Neutral P53634 Y340C Disease Neutral P53634 R272P Disease Disease P53634 V249F Disease Disease P53634 Q286R Disease Disease P53634 D236Y Disease Disease P53634 Y412C Disease Disease P53634 V129E Disease Neutral P53634 G301S Disease Disease P53634 H127P Disease Disease P53634 R272H Disease Disease P53634 H405N Disease Disease P53634 I453V Neutral Neutral P53634 Y347C Disease Neutral P53634 E401K Neutral Disease P53634 Q252L Disease Disease P53634 W429C Disease Disease P53634 E447G Disease Neutral P53634 Y304N Disease Disease P53634 G300S Disease Disease P53634 H405R Disease Disease P53634 C291Y Disease Disease P53634 W39S Disease Disease P53634 Q312R Disease Neutral P53634 T153I Neutral Neutral P53634 G300D Disease Disease P53634 R339C Disease Neutral P53634 E319G Disease Disease P53634 G301V Disease Disease O15527 R46Q Disease Disease O15527 R229Q Neutral Disease O15527 D322N Neutral Neutral O15527 S326C Neutral Neutral O15527 G12E Disease Neutral O15527 S232T Disease Neutral O15527 A85S Disease Neutral O15527 A288V Neutral Neutral O15527 S320T Neutral Neutral O15527 R154H Disease Disease O15527 R131Q Disease Disease P06702 H20R Neutral Disease Q502X0 E48K Neutral Neutral Q9UGM5 G202S Neutral Disease Q8NFB2 M179V Neutral Disease Q8NFB2 C243S Neutral Neutral Q5MJ10 T8I Neutral Neutral O43699 L251F Neutral Disease Q9Y336 K100E Neutral Neutral Q9Y336 A316D Neutral Disease Q9Y336 S125N Neutral Neutral Q9Y336 N147K Neutral Disease Q9Y336 K131Q Neutral Neutral Q9NYZ4 S170P Neutral Neutral O43699 L46V Neutral Neutral Q9Y336 V349A Neutral Neutral Q9Y336 A315E Neutral Neutral Q12770 V798I Neutral Neutral Q13698 R1539C Neutral Disease Q13698 L458H Neutral Disease Q13698 R1239G Disease Disease Q13698 R528H Disease Disease Q13698 R1239H Disease Disease Q9UL58 M376V Neutral Neutral Q9UL58 M119V Neutral Neutral P45880 A24V Neutral Neutral Q8N9N8 S159N Neutral Neutral Q8N9N8 D23N Neutral Neutral O43353 L268V Neutral Disease O43353 I259T Neutral Neutral O43353 K313N Neutral Neutral P11532 F3228L Disease Neutral P11532 Y231N Disease Disease P11532 C3340Y Disease Disease P11532 A3421V Disease Neutral P11532 A171P Disease Disease P11532 H2921R Disease Neutral P11532 A168D Disease Disease P11532 K18N Disease Disease P11532 D645G Disease Neutral P11532 K773E Disease Neutral P11532 L54R Disease Disease P11532 D3335H Disease Disease P11532 T279A Disease Neutral P11532 N1672K Disease Neutral P22966 I444T Neutral Disease P22966 R705Q Neutral Neutral P22966 R712S Neutral Neutral P22966 T613M Neutral Disease P22966 F477V Neutral Neutral P22966 S32P Neutral Neutral P22966 T342M Neutral Neutral P22966 S49G Neutral Neutral P22966 Q722P Neutral Neutral Q9Y385 G55V Neutral Disease Q9Y385 L229V Neutral Neutral Q24JQ0 L131F Neutral Neutral P78556 V47M Neutral Neutral Q9UH65 Q505E Neutral Neutral Q9H4E7 R578H Neutral Neutral Q9H4E7 N287T Neutral Neutral P48201 G93E Neutral Disease Q06055 M141K Neutral Disease Q06055 S58I Neutral Disease Q7Z3J2 A506V Neutral Neutral Q7Z3J2 Y32C Neutral Disease Q7Z3J2 N186I Neutral Neutral Q6UX06 S36P Neutral Neutral Q04721 C444Y Disease Disease Q04721 V1667F Neutral Neutral P46531 Q300R Neutral Neutral P41181 L121F Neutral Disease P41181 E258K Disease Neutral P41181 Q57P Neutral Disease P41181 V194I Neutral Neutral Q5XXA6 G983R Neutral Neutral Q5XXA6 F608S Neutral Disease Q5T160 I331V Neutral Neutral Q5T160 D367G Neutral Disease Q5T160 K291R Neutral Neutral P43115 M169L Neutral Neutral P43115 P375L Neutral Neutral P43115 N366S Neutral Neutral O95399 S74N Neutral Neutral Q13591 V246L Neutral Disease Q13591 S792L Neutral Neutral Q8N5N7 L127F Neutral Neutral Q5QJE6 A430V Neutral Neutral Q5QJE6 Y676F Neutral Neutral Q5QJE6 T341A Neutral Neutral Q5QJE6 E309D Neutral Neutral Q96DN2 P842R Neutral Neutral Q9NZ94 R451C Disease Neutral Q96AD5 L219F Neutral Neutral Q96AD5 P195L Disease Disease Q96AD5 N252K Neutral Disease Q96AD5 L481P Neutral Neutral P98168 G376S Neutral Neutral P98169 A736T Neutral Neutral P98169 D764N Neutral Neutral P98169 N760S Neutral Neutral P98169 T791R Neutral Neutral P98161 R2888G Neutral Neutral P98161 P3193L Neutral Disease P98161 H2638R Neutral Neutral P98161 Q2735L Neutral Neutral P98161 M3678T Disease Neutral P98161 H2921P Disease Disease P98161 R4136G Disease Disease P98161 G3139V Neutral Disease P98161 V1956E Disease Disease P98161 L2816P Disease Disease P98161 S3562N Neutral Neutral P98161 A3512V Neutral Neutral P98161 V3375M Disease Neutral P98161 Q4225P Disease Disease P98161 A88V Neutral Neutral P98161 R3753W Disease Disease P98161 L3511V Disease Neutral P98161 T2708M Neutral Neutral P98161 R2392P Disease Disease P98161 S2423F Disease Neutral P98161 V2782M Neutral Neutral P98161 R4276W Disease Neutral P98161 S4190F Neutral Neutral P98161 G4032D Disease Disease P98161 Y2379C Neutral Disease P98161 V2768M Disease Neutral P98161 L3852P Disease Disease P98161 P2674S Neutral Neutral P98161 Q3016R Disease Neutral P98161 L13Q Disease Neutral P98161 V4058A Neutral Neutral P98161 M2764T Disease Neutral P98161 P1786L Neutral Neutral P98161 G1166S Disease Disease P98161 R324L Disease Disease P98161 R2765C Neutral Neutral P98161 P2734T Neutral Neutral P98161 W1399R Neutral Neutral P98161 R2329W Disease Neutral P98161 L2763V Disease Neutral P98161 I4045V Neutral Neutral P98161 E2771K Disease Neutral P98161 F3066L Neutral Disease P98161 E3632D Neutral Neutral P98161 R2791Q Disease Neutral P98161 D2604N Neutral Neutral P98161 W139C Disease Disease P98161 H3311R Neutral Neutral P98161 W967R Disease Disease P98161 E2548Q Neutral Neutral P98161 Y2336D Disease Disease P98161 M2760T Disease Neutral P98161 G3560R Disease Neutral P98161 G2814R Neutral Neutral P98161 T2649I Disease Neutral P98161 D3815N Disease Neutral P98161 R3039C Disease Neutral P98161 T2582M Neutral Neutral P98161 Q2519L Disease Neutral P98161 R2985G Disease Neutral P98161 R2408C Disease Neutral P98161 T3510M Neutral Neutral P98161 L2696R Disease Neutral P98161 V3285I Disease Neutral P98161 L845S Disease Disease P98161 A2752D Disease Disease P98161 R3247H Disease Neutral P98161 V2905I Neutral Neutral P98161 R4154C Disease Disease P98161 R2746P Neutral Neutral P98161 T3382M Disease Neutral P98161 L2993P Disease Disease P98161 A4059V Neutral Neutral P98161 D2972N Neutral Neutral P98161 V3008L Disease Neutral P98161 T2250M Disease Neutral P98161 E2966D Neutral Neutral P98161 R1995H Neutral Neutral P98161 S75F Disease Neutral P98161 P2471L Disease Disease P98161 I2826T Disease Disease P98161 R3719Q Disease Neutral P98161 G2858S Disease Disease P98161 R2761P Disease Disease P60660 T103P Neutral Disease P30101 K415R Neutral Neutral Q9UBS4 I264V Neutral Neutral Q15269 F551I Neutral Disease Q15269 D25N Neutral Disease O15018 D1343E Neutral Neutral O15018 T1425M Neutral Neutral O15018 R2247Q Neutral Neutral O15018 A1649V Neutral Neutral O15018 T1274A Neutral Neutral O15018 Q1258K Neutral Neutral Q9BRT8 A8V Neutral Neutral Q08050 S643P Neutral Neutral Q08050 P673L Neutral Neutral Q08050 F450L Neutral Neutral Q08050 P669R Neutral Neutral Q08050 A402E Neutral Neutral P60328 R17H Neutral Neutral P35557 T209M Disease Disease P35557 E70K Disease Disease P35557 T228M Disease Disease P35557 K414E Disease Neutral P35557 E256K Disease Disease P35557 I110T Disease Disease P35557 F150S Disease Disease P35557 V455M Disease Neutral P35557 G261E Disease Disease P35557 G80S Disease Disease P35557 E221K Disease Neutral P35557 G385V Disease Disease P35557 W257R Disease Disease P35557 A11T Neutral Neutral P35557 R392C Disease Disease P35557 C213R Disease Disease P35557 L309P Disease Disease P35557 E300Q Disease Disease P35557 M107T Neutral Neutral P35557 G175R Disease Disease P35557 A53S Disease Neutral P35557 V367M Disease Disease P35557 V203A Disease Disease P35557 C382Y Disease Disease P35557 R36W Disease Disease P35557 S131P Disease Disease P35557 G261R Disease Disease P35557 D4N Neutral Neutral P35557 L164P Disease Disease P35557 G80A Disease Disease P35557 M210K Disease Disease P35557 A119D Disease Disease P35557 H137R Disease Neutral P35557 Y108H Disease Neutral P35557 M210T Disease Disease P35557 A188T Disease Disease P35557 G227C Disease Disease P35557 T168P Disease Disease P35557 E300K Disease Disease P35557 A384T Disease Disease P35557 G299R Disease Disease P35557 S336L Disease Disease P35557 V226M Disease Disease P35557 E279Q Disease Neutral P35557 V182M Disease Disease P35557 A259T Disease Disease Q9Y5W3 R145P Neutral Neutral Q9Y5W3 L104P Neutral Neutral Q2TAM9 D120N Neutral Neutral A6NKF1 L185P Neutral Disease A6NKF1 T8P Neutral Neutral Q8NBV8 T152M Neutral Neutral Q8NBV8 R143Q Neutral Neutral Q2M2W7 V92I Neutral Neutral O60331 D253N Disease Disease Q9H0K6 I343V Neutral Neutral Q9H0K6 K264E Neutral Neutral Q9H0K6 I92M Neutral Neutral P50616 K319R Neutral Neutral Q9H6U8 P506L Neutral Neutral Q9H6U8 E523K Disease Neutral Q9H6U8 V289I Neutral Neutral Q9H6U8 Y287C Disease Disease P09622 T104K Neutral Neutral P09622 L331V Neutral Neutral Q8N394 A315T Neutral Neutral Q8N394 Y443S Neutral Disease Q8IWC1 Q628R Neutral Neutral Q8IWC1 E502A Neutral Neutral Q8NCR3 F242L Neutral Neutral Q8NCR3 W183L Neutral Disease Q9NWW5 M241T Disease Disease Q9NWW5 G123D Disease Disease Q9NWW5 W300R Disease Disease Q9NWW5 R62H Disease Disease Q9NWW5 Y221S Disease Disease Q9NWW5 E72Q Disease Neutral Q9NWW5 P299L Disease Disease Q9UNN8 S219G Neutral Neutral Q7RTP0 G106R Disease Disease Q7RTP0 T45R Disease Disease Q9BWP8 H219R Neutral Neutral P54136 F397Y Neutral Neutral P54136 V3I Neutral Neutral O75638 W138R Neutral Neutral O75638 E89Q Neutral Neutral O75638 R6Q Neutral Neutral Q99715 G3058S Neutral Disease Q12765 Q338R Neutral Neutral Q96FV2 E273Q Neutral Neutral Q96FV2 V323M Neutral Neutral Q96FV2 S411G Neutral Neutral Q96FV2 Q330R Neutral Neutral Q0VDG4 V179A Neutral Neutral Q96FV2 K103R Neutral Neutral O95868 S34T Neutral Neutral O95868 L9V Neutral Neutral P39019 P47L Disease Disease P39019 L18P Disease Disease P39019 T55M Disease Neutral P39019 R56Q Disease Disease P39019 A61E Disease Disease P39019 R62W Disease Disease P39019 L131P Disease Disease P39019 R62Q Disease Disease P39019 W52R Disease Disease P39019 R101H Disease Disease P39019 G120R Disease Disease P39019 V15F Disease Disease Q8N6H7 S411N Neutral Neutral Q9H3N8 A138V Neutral Disease Q9H3N8 H206R Neutral Neutral O75845 Y46S Disease Disease O75845 G211D Disease Disease O75845 R29Q Disease Disease P54845 S50T Disease Neutral Q9UHG2 A31T Neutral Neutral Q01518 C236G Neutral Neutral P40123 Y316C Neutral Neutral Q01518 I245S Neutral Neutral P40123 T311A Neutral Neutral Q01518 Y249D Neutral Neutral Q01518 G229C Neutral Neutral Q01518 C247G Neutral Neutral Q01518 S256A Neutral Neutral Q7Z7G8 G2645D Disease Neutral Q7Z7G8 Y2341C Disease Disease Q7Z7G8 N2993S Disease Neutral Q7Z7G8 L2193R Disease Disease Q6UXN2 W73R Neutral Neutral Q6UXN2 T168I Neutral Neutral Q6UXN2 T146K Neutral Neutral Q9UIA9 C835Y Neutral Disease Q9UIA9 E398D Neutral Neutral Q9Y6D9 S29L Disease Neutral Q9Y6D9 T299A Disease Neutral Q9Y6D9 R556C Disease Neutral Q9Y6D9 E569K Disease Neutral Q9Y6D9 R360Q Disease Neutral Q9Y6D9 R556H Disease Neutral Q9Y6D9 E516K Disease Neutral Q9Y6D9 R572H Disease Neutral Q9Y6D9 E511K Neutral Neutral Q9Y6D9 R558H Disease Neutral Q9Y6D9 N160S Neutral Neutral Q9Y6D9 T500M Neutral Neutral Q9Y6D9 R59C Disease Neutral Q92519 H4R Neutral Neutral O75173 D304N Neutral Disease O75173 R626Q Neutral Neutral O75173 P552T Neutral Disease O75173 T4I Neutral Neutral O75173 M369V Neutral Disease O75173 R836K Neutral Neutral O75173 T564A Neutral Neutral Q96RR1 W315L Disease Disease Q96RR1 A359T Disease Neutral Q96RR1 R354P Disease Disease Q96RR1 V368I Disease Neutral Q96RR1 A475P Disease Disease Q96RR1 S369Y Disease Neutral Q96RR1 L381P Disease Disease Q96RR1 K319E Disease Neutral Q96RR1 T457I Disease Neutral Q96RR1 K319T Disease Neutral Q96RR1 S369P Disease Neutral Q96RR1 I367T Disease Disease Q96RR1 W474C Disease Disease Q96RR1 P335L Disease Neutral Q96RR1 R374Q Disease Neutral P07902 F117S Disease Disease P07902 H184Q Disease Disease P07902 M142V Disease Disease P07902 L282V Disease Neutral P07902 Q118H Disease Neutral P07902 R51Q Disease Disease P07902 K127E Disease Neutral P07902 H132Y Disease Neutral P07902 T138M Disease Neutral P07902 Q212H Disease Neutral P07902 R123G Disease Disease P07902 V125A Disease Neutral P07902 R262P Disease Neutral P07902 Q252H Disease Disease P07902 M336L Disease Neutral P07902 D28Y Disease Disease P07902 R259W Disease Disease P07902 I198T Disease Neutral P07902 R258C Disease Disease P07902 Y323D Disease Disease P07902 L62M Neutral Neutral P07902 Q317H Disease Disease P07902 M142K Disease Disease P07902 Q317R Disease Disease P07902 N314D Neutral Neutral P07902 S45L Disease Disease P07902 V150L Disease Disease P07902 R272G Disease Disease P07902 D98N Disease Disease P07902 I32N Disease Disease P07902 H319Q Disease Disease P07902 R148G Disease Disease P07902 V151A Disease Neutral P07902 F294Y Disease Disease P07902 P183T Disease Disease P07902 W167R Disease Disease P07902 F171S Disease Disease P07902 R148Q Disease Neutral P07902 R67C Disease Neutral P07902 S192N Disease Neutral P07902 I198M Disease Neutral P07902 G179D Disease Disease P07902 S135W Disease Disease P07902 L139P Disease Disease P07902 G55C Disease Disease P07902 Q188R Disease Disease P07902 E291K Disease Disease P07902 M129T Disease Disease P07902 H114L Disease Neutral P07902 S143L Disease Disease P07902 Y209C Disease Disease P07902 Y209S Disease Disease P07902 D113N Disease Neutral P07902 K229N Disease Neutral P07902 A320T Disease Disease P07902 V44M Disease Disease P07902 L289R Disease Disease P07902 L74P Disease Disease P07902 R204P Disease Disease P07902 R123Q Disease Neutral P07902 W249R Disease Disease P07902 E308K Disease Disease P07902 R148W Disease Disease P07902 Y323H Disease Disease P07902 P325L Disease Disease P07902 W154G Disease Disease P07902 Y251S Disease Disease P07902 Q344K Disease Neutral P07902 A199T Disease Neutral P07902 K334R Disease Disease P07902 F194L Disease Disease P07902 Q38P Disease Disease P07902 K285N Disease Disease P07902 R328H Disease Disease P07902 V44L Disease Disease P07902 C130Y Disease Disease P07902 R333W Disease Disease P07902 S329F Disease Disease P07902 L217P Disease Disease P07902 A330V Disease Disease P07902 R51L Disease Disease P07902 T350A Disease Disease P07902 A81T Disease Disease P07902 S135L Disease Disease P07902 P324S Disease Disease P07902 Y251C Disease Disease P07902 R231H Disease Disease P07902 E203K Disease Disease P07902 L226P Disease Disease P07902 R333Q Disease Disease P07902 N97S Disease Disease P07902 R333G Disease Disease P07902 R201H Disease Neutral P07902 L195P Disease Disease Q2TBA0 C617R Neutral Neutral Q2TBA0 N345S Neutral Neutral P12830 E336D Neutral Neutral P12830 N315S Disease Neutral P12830 H123Y Disease Neutral P12830 E880K Neutral Disease P12830 C695R Neutral Disease P55283 K625R Neutral Neutral P12830 T470I Neutral Neutral P12830 T340A Disease Neutral P19022 A21T Neutral Neutral P12830 R598Q Disease Neutral P12830 V487A Disease Neutral P19022 I212L Neutral Neutral P19022 N845S Neutral Neutral P12830 D370A Disease Neutral P19022 A118T Neutral Neutral P12830 V832M Neutral Neutral P12830 T193P Disease Disease P12830 D244G Disease Neutral P19022 S196T Neutral Neutral P12830 L630V Neutral Neutral P12830 V473D Disease Neutral P12830 A617T Disease Neutral P12830 A592T Disease Neutral P12830 L711V Disease Neutral P12830 S838G Disease Neutral P12830 E463Q Disease Neutral P12830 L478P Neutral Disease Q8N442 L58P Neutral Disease Q8N442 T329I Neutral Disease Q8NCT1 A79T Neutral Neutral Q8NCT1 P358S Neutral Neutral Q8NCT1 S347P Neutral Neutral Q9HA64 A57V Neutral Disease Q8N1Q8 D197G Neutral Neutral Q8N1Q8 Y55S Neutral Disease Q8N1Q8 L206V Neutral Neutral Q5T1C6 S38C Neutral Neutral Q5T1C6 L17R Neutral Neutral Q9NRW4 R119H Neutral Disease P42574 E190D Neutral Disease Q9NZH6 T42A Neutral Neutral Q9NZH6 D218N Neutral Neutral Q9NZH6 W164R Neutral Neutral Q9NZH6 P108L Neutral Neutral Q9NZH6 R152W Neutral Neutral Q9NZH6 G31V Neutral Neutral Q9ULE0 A495T Neutral Neutral Q9ULE0 Y593C Neutral Neutral Q9UM44 N344K Neutral Neutral Q9UM44 I30T Neutral Neutral Q9UM44 S364R Neutral Neutral Q96I51 R30G Neutral Neutral Q04656 G853R Disease Disease P35670 E1064A Disease Disease P35670 A14D Neutral Neutral P35670 L641S Disease Neutral P35670 G96D Neutral Disease P35670 R969Q Disease Neutral P35670 G1101R Disease Disease P35670 G943S Disease Disease P35670 L1373R Disease Disease P35670 E1173K Disease Disease Q04656 L706R Disease Disease P35670 V446L Neutral Neutral P35670 A1168S Disease Neutral P35670 D1222V Disease Disease P35670 Q1095P Disease Disease P35670 C1104F Disease Disease Q04656 G1369R Disease Disease Q04656 G1300E Disease Disease P35670 R778W Disease Disease P35670 N1270S Disease Disease P35670 G1341D Disease Disease P35670 G711W Disease Disease Q04656 T669I Neutral Disease P35670 C985Y Disease Disease P35670 G710A Disease Neutral P35670 R919W Disease Disease P35670 A1278V Disease Disease P35670 V864I Neutral Neutral P35670 V949G Disease Neutral P35670 Y741C Disease Disease Q04656 G727R Disease Disease P35670 W1353R Disease Disease P35670 D1267A Disease Disease Q04656 V767L Disease Disease P35670 I1148T Disease Neutral P35670 S744P Disease Disease P35670 R778Q Disease Neutral P35670 S693C Disease Neutral P35670 R1041W Disease Disease P35670 E1068G Disease Disease Q04656 G1118D Disease Disease P35670 G711E Disease Disease P35670 R1322P Disease Disease P35670 V1216M Disease Disease P35670 L795R Disease Disease P35670 F1094L Disease Neutral P35670 L1327V Disease Neutral Q04656 G1019D Disease Disease P35670 P1098R Disease Disease P35670 R875G Neutral Neutral P35670 G1213V Disease Disease P35670 G1099S Disease Disease Q04656 G860V Disease Disease P35670 E1064K Disease Disease Q04656 C1000R Disease Disease Q04656 L1100P Disease Disease P35670 R778L Disease Disease Q04656 A1007V Disease Disease P35670 G1176R Disease Disease P35670 D765G Disease Neutral P35670 G1355C Disease Disease P35670 M769V Disease Neutral Q04656 N1304K Disease Disease P35670 L708P Disease Disease P35670 G710R Disease Disease P35670 G1186S Disease Disease P35670 H1207R Neutral Neutral P35670 T935M Disease Disease P35670 D918E Disease Disease P35670 G626A Disease Disease P35670 R1038K Disease Neutral Q04656 D1305A Disease Disease P35670 P690L Disease Disease P35670 H1069Q Disease Disease P35670 D765N Disease Disease P35670 A1063V Disease Neutral P35670 V1140A Neutral Neutral Q04656 G1302R Disease Disease P35670 Q1142H Disease Neutral P35670 T977M Disease Disease P35670 P1273L Disease Disease Q04656 R703H Neutral Neutral P35670 G710S Disease Neutral P35670 I1102T Disease Disease P35670 N565S Neutral Neutral P35670 G869V Disease Disease P35670 Q898R Disease Disease Q04656 I1345F Disease Neutral Q04656 I1464V Neutral Neutral P35670 R778G Disease Disease P35670 L1083F Disease Neutral P35670 V1262F Disease Disease P35670 G1089V Disease Neutral Q04656 S1397F Disease Disease P35670 T1220M Disease Disease Q04656 A1362V Disease Disease P35670 T1031I Disease Disease Q04656 G1302V Disease Disease P35670 G711R Disease Disease P35670 S721P Disease Disease P35670 I390V Neutral Neutral Q04656 G1015D Disease Disease P35670 P992L Disease Disease P35670 V1297I Neutral Neutral P35670 G1266R Disease Disease P35670 L776V Neutral Disease Q04656 A1325V Disease Disease P35670 G1089E Disease Disease P35670 V1109M Neutral Disease P35670 W1153R Disease Neutral P35670 D918N Disease Disease P35670 V1146M Disease Disease P35670 R1151H Disease Neutral P35670 L492S Disease Disease Q04656 A629P Disease Disease P35670 I1336T Disease Disease P35670 L1043P Disease Disease P35670 G1355S Disease Disease P35670 P768H Disease Neutral P35670 G691R Disease Disease P35670 G1061E Disease Disease P35670 L1373P Disease Disease P35670 D1271N Disease Disease P35670 R723G Neutral Disease P35670 G1266V Disease Disease P35670 M769R Disease Disease P35670 G943D Disease Disease Q04656 R844H Disease Neutral P35670 M769I Disease Disease P35670 V1239G Disease Disease P35670 L795F Disease Disease P35670 P1245S Neutral Disease P35670 K952R Neutral Neutral P35670 R616W Disease Disease P35670 G85V Disease Disease P35670 L466V Neutral Neutral Q04656 G876R Disease Disease P35670 M1169T Disease Neutral Q04656 G1315R Disease Disease P35670 K832R Neutral Neutral P35670 T1232P Disease Disease P35670 N41S Disease Neutral Q04656 L1006P Disease Disease P35670 T1033S Disease Disease P35670 A1003T Disease Disease P35670 L1255I Disease Disease P35670 T1033A Disease Disease P35670 S975Y Disease Disease P35670 A1003V Disease Disease Q04656 Q924R Disease Disease P35670 T737R Disease Disease P35670 V1106D Disease Disease P35670 P1052L Disease Disease P35670 I967F Disease Disease P35670 A1358S Disease Disease Q04656 G876E Disease Disease P35670 A1183G Disease Disease P35670 S1310R Disease Disease P35670 A1183T Disease Disease P35670 A874V Disease Disease P35670 G891V Disease Disease P35670 G1111D Disease Neutral P35670 M645R Disease Disease P35670 S406A Neutral Neutral P35670 P760L Disease Disease P35670 Y713C Disease Disease P35670 R1041P Disease Disease P35670 V456L Neutral Neutral P35670 G869R Disease Disease P35670 D642H Disease Disease P35670 G1186C Disease Disease P35670 A1018V Disease Disease P35670 T933P Disease Disease Q04656 K1282E Disease Disease P35670 V995A Neutral Disease Q04656 D1044G Disease Disease P35670 D1222Y Disease Disease P35670 S1363F Disease Disease P35670 V890M Disease Disease P35670 L1305P Disease Disease Q04656 L873R Disease Disease P35670 I747F Disease Neutral P35670 P840L Disease Disease P35670 R616Q Disease Neutral P35670 W1153C Disease Disease P35670 M1169V Neutral Neutral P35670 R919G Disease Disease P35670 S921N Disease Neutral P35670 I857T Disease Disease P35670 T1434M Disease Neutral P35670 T1143N Neutral Neutral Q04656 G1255R Disease Disease P35670 G1035V Disease Disease Q04656 S637L Disease Neutral P35670 M665I Disease Disease Q04656 S1344R Disease Disease P35670 D1279G Disease Disease P35670 K1248N Disease Disease Q9GZQ3 A6T Neutral Neutral P11177 P344S Disease Disease P11177 Y132C Disease Disease P11177 L31V Neutral Neutral Q68J44 S137R Neutral Disease Q5IJ48 A351T Disease Neutral Q5IJ48 T1110M Neutral Neutral Q5IJ48 H746Q Neutral Neutral Q5IJ48 R534Q Disease Neutral Q5IJ48 R610W Neutral Neutral Q5IJ48 G159A Neutral Disease Q5IJ48 M145T Neutral Neutral Q92887 F562L Neutral Neutral O95255 R1314W Disease Disease Q92887 R353H Neutral Disease O95255 R765Q Disease Disease Q92887 V1188E Neutral Neutral O95255 R265G Neutral Disease O95255 I1424T Disease Disease O95255 K281E Neutral Neutral O95255 I319V Neutral Neutral O95255 G1354R Disease Disease Q92887 R1150H Disease Disease O15438 Q1365R Neutral Neutral P33527 C43S Neutral Disease Q92887 M246L Neutral Neutral O95255 L673P Disease Disease O95255 V614A Neutral Neutral O95255 R1314Q Disease Disease O95255 V1298F Disease Disease O15438 S607N Neutral Neutral O95255 S1121W Disease Disease O15438 G11D Neutral Neutral Q92887 I670T Neutral Neutral O15438 R1286G Neutral Neutral O95255 R1339C Disease Disease O15438 S346F Neutral Disease O95255 N411K Disease Disease Q92887 D333G Neutral Neutral P33527 S1512L Neutral Disease Q92887 T1273A Neutral Neutral O95255 R1138P Disease Disease O95255 H632Q Neutral Neutral Q92887 C1515Y Neutral Disease O95255 A1303P Disease Disease P33527 R1058Q Neutral Neutral O95255 W1241C Neutral Neutral O95255 G61D Neutral Disease P33527 T117M Neutral Neutral Q92887 V417I Neutral Neutral O95255 Q1347H Disease Disease O95255 T1301I Disease Disease Q92887 S281N Neutral Neutral O95255 D1361N Disease Disease P33527 R433S Neutral Disease Q92887 K495E Neutral Neutral O95255 W64R Neutral Neutral O95255 R1268Q Neutral Disease Q92887 Q1382R Disease Disease O95255 A455P Disease Disease Q92887 A1450T Neutral Disease Q92887 I1173F Disease Disease O95255 R1114P Disease Disease Q92887 N1063S Neutral Neutral O95255 G1203D Disease Disease P33527 R633Q Neutral Disease O95255 N497K Neutral Neutral O95255 G1321S Disease Disease O95255 R1138Q Disease Disease O15438 R1297H Neutral Disease Q92887 R1181L Neutral Neutral O95255 F568S Disease Disease Q92887 L849R Neutral Disease O95255 R1138W Disease Disease O95255 G207R Neutral Disease Q92887 P1291L Neutral Disease Q92887 T486I Neutral Neutral O95255 T364R Disease Disease O15438 R1381S Neutral Disease P33527 R723Q Neutral Disease O95255 L953H Neutral Disease Q92887 I1036T Neutral Disease Q92887 S789F Neutral Disease O15438 R1348C Neutral Disease Q92887 R768W Disease Disease P33527 T73I Neutral Neutral O95255 G1302R Disease Disease Q92887 I982V Neutral Neutral O95255 R518Q Disease Disease Q8TAA9 A116T Neutral Neutral Q8TAA9 E347A Neutral Neutral Q8TAA9 V239I Disease Neutral Q8TAA9 M328T Disease Neutral Q8TAA9 R274Q Disease Disease Q8N815 T145P Neutral Disease Q8WUM4 S730L Neutral Neutral Q8N3J5 N94K Neutral Disease P15289 A314T Disease Neutral P15289 Y201C Disease Disease P15289 D335V Disease Disease P15289 S96L Disease Disease P15289 G122S Disease Disease P15289 R288C Disease Neutral P15289 R384C Disease Disease P15289 A464V Neutral Neutral P15289 H397Y Disease Neutral P15289 P82L Disease Disease P15289 N350S Neutral Neutral P15289 L76P Neutral Disease P15289 G86D Disease Disease P15289 E382K Disease Neutral P15289 P426L Disease Neutral P15289 C300F Disease Neutral P15289 W193C Neutral Neutral P15289 D169N Disease Neutral P15289 S250Y Disease Disease P15289 G99D Disease Disease P15289 F356V Neutral Neutral P15289 P231T Disease Disease P15289 G154D Disease Neutral P15289 G245R Disease Neutral P15289 T391S Neutral Neutral P15289 P136L Disease Disease P15289 P167R Disease Neutral P15289 R311Q Disease Disease P15289 I179S Disease Disease P15289 K367N Disease Disease P15289 R390Q Disease Disease P15289 R84Q Disease Disease P15289 L135P Disease Disease P15289 G309S Disease Disease P15289 C172Y Disease Neutral P15289 D152Y Disease Disease P15289 P425T Disease Neutral P15289 G119R Disease Disease P15289 R496H Neutral Neutral P15289 P155R Disease Neutral P15289 R370W Disease Disease P15289 P377L Disease Neutral P15289 A224V Disease Neutral P15289 S96F Disease Disease P15289 R244C Disease Neutral P15289 S295Y Disease Neutral P15289 R244H Disease Neutral P15289 R370Q Disease Disease P15289 T274M Disease Disease P15289 N440S Neutral Disease P15289 A212V Disease Neutral P15289 R390W Disease Disease P15289 S95N Disease Neutral Q7L4E1 V100A Neutral Neutral Q7L4E1 G212S Neutral Neutral Q7L4E1 E78K Neutral Neutral Q9NUL3 M198V Neutral Neutral Q9H898 T201A Neutral Neutral P46779 R66L Neutral Disease Q5VT97 I406M Neutral Neutral Q5VT97 V1079I Neutral Neutral Q5VT97 V491I Neutral Neutral Q5T749 C113R Neutral Disease Q5T749 V37A Neutral Neutral Q5T749 Q14H Neutral Neutral Q5T749 P532T Neutral Neutral Q5T749 R168H Neutral Neutral Q5T749 C413S Neutral Neutral P37058 S65L Disease Disease P37058 S232L Disease Neutral P37058 Q176P Disease Disease P37058 P282L Disease Disease P37058 E215D Disease Disease P37058 N130S Disease Disease P37058 C268Y Disease Neutral P37058 R80W Disease Disease P37058 R80Q Disease Disease P37058 V205E Disease Disease P37058 A203V Disease Disease P37058 A56T Disease Disease P37058 M235V Disease Disease P37058 V31I Neutral Neutral P37058 G289S Neutral Disease P37058 F208I Disease Neutral A7MD48 R547S Neutral Neutral A7MD48 S243N Neutral Neutral A7MD48 R406Q Neutral Neutral P28360 V114G Disease Neutral P28360 G91D Disease Neutral P35548 R172H Disease Disease P35548 T129M Neutral Neutral P28360 M61K Disease Disease P28360 E78V Disease Neutral P28360 G116E Disease Neutral P35548 P148H Disease Neutral P28360 R151S Disease Neutral P28360 R196P Disease Disease P35548 L154P Disease Disease Q86X27 N225S Neutral Disease Q5W0Q7 P384S Neutral Neutral Q5W0Q7 E173G Neutral Neutral Q5W0Q7 T1043S Neutral Neutral Q5W0Q7 S950N Neutral Neutral Q5W0Q7 L531S Neutral Neutral Q5W0Q7 S739C Neutral Neutral Q5W0Q7 A522P Neutral Neutral Q9Y5F9 A722T Neutral Neutral Q9UN74 P184S Neutral Neutral Q9Y5I3 Y732C Neutral Neutral Q9Y5F9 P684S Neutral Neutral Q9Y5H8 I318V Neutral Neutral Q9Y5I3 N449H Neutral Disease Q9Y5H4 V152I Neutral Neutral Q9Y5H8 C759Y Neutral Disease Q9Y5F6 D570G Neutral Neutral Q9Y5H2 F104L Neutral Disease Q9Y5H6 N403T Neutral Neutral Q9Y5H6 S78N Neutral Disease Q9Y5H9 V106L Neutral Neutral P08910 R253Q Neutral Neutral Q9H2U2 K282N Neutral Disease Q9NXK6 I24T Neutral Disease Q86XH1 K452R Neutral Neutral Q7Z5L9 A254V Neutral Neutral Q8N0X2 K425T Neutral Neutral Q8N0X2 Q361H Neutral Neutral Q86X02 D300E Neutral Neutral P53671 R213C Neutral Disease P53667 R422Q Neutral Disease P53671 P296R Neutral Neutral P53667 G190A Neutral Neutral P53671 G35S Neutral Neutral P53667 S247N Neutral Neutral P53671 D45N Neutral Neutral P53671 R418C Neutral Disease P04920 R311W Neutral Neutral P04920 G26E Neutral Neutral P04920 L1204F Neutral Neutral P04920 E202V Neutral Neutral Q15058 P1633A Neutral Neutral Q63HQ2 R111H Neutral Neutral Q63HQ2 W229R Neutral Neutral Q63HQ2 H576N Neutral Neutral Q63HQ2 T473M Neutral Neutral P31327 T544M Disease Neutral P31327 G1376S Neutral Neutral P31327 F1266S Neutral Disease P31327 V457G Disease Disease P31327 L843S Disease Disease P31327 K875E Disease Disease P31327 H337R Disease Disease P31327 T1406N Neutral Neutral P31327 Q810R Disease Disease P31327 M1283L Neutral Disease P31327 T344A Neutral Neutral P31327 S918P Disease Disease P31327 R850H Disease Disease Q8IYS0 L644P Neutral Disease Q3LIE5 L92R Neutral Neutral Q3LIE5 E337G Neutral Neutral Q13510 Y36C Disease Disease Q13510 M72V Neutral Neutral Q13510 G235R Disease Disease Q13510 V369I Neutral Neutral Q13510 Q22H Disease Neutral Q13510 L182V Disease Disease Q13510 A246V Neutral Neutral Q13510 E138V Disease Disease Q13510 H23D Disease Neutral Q13510 D124E Neutral Neutral Q13510 P362R Disease Disease Q13510 T222K Disease Neutral Q13510 R254G Disease Disease Q13510 V93I Neutral Neutral Q13510 N320D Disease Disease Q13510 V97E Disease Neutral Q9BYT8 P704S Neutral Neutral Q16633 Q194R Neutral Neutral Q16633 T141A Neutral Neutral Q1HG43 S313G Neutral Neutral O43548 A352G Neutral Neutral O95932 M58V Neutral Neutral Q08188 S249N Neutral Neutral P00488 R682H Disease Neutral Q08188 I163L Neutral Disease P00488 T551I Neutral Neutral Q08188 R654G Neutral Disease P00488 L589Q Neutral Neutral P21980 M330R Disease Disease P00488 V651I Neutral Neutral P16452 A112T Disease Disease P00488 P565L Neutral Neutral P00488 V35L Neutral Neutral P00488 Q652E Neutral Neutral Q08188 K562R Neutral Neutral P00488 V40I Neutral Neutral P16452 R280Q Disease Disease Q08188 K13T Neutral Neutral O43548 P67S Neutral Disease P21980 I331N Disease Disease O43548 G113C Disease Disease P00488 Y205F Neutral Disease O43548 T109M Neutral Neutral O75916 W299R Disease Disease Q684P5 L202M Neutral Neutral Q8NDL9 G649D Neutral Neutral P49748 R613W Disease Disease P49748 F458L Disease Neutral P49748 V174M Disease Disease P49748 R459W Disease Disease P49748 G290D Disease Disease P49748 K382Q Disease Disease P49748 G441D Disease Disease P49748 L243R Disease Disease P49748 L602I Disease Neutral P49748 R469W Disease Disease P49748 V283A Disease Disease P49748 G185S Disease Disease P49748 G294E Disease Disease P49748 R366C Disease Disease P49748 S623F Neutral Disease P49748 A281D Disease Disease P49748 D454N Disease Neutral P49748 L502P Disease Disease P49748 V317A Disease Disease P49748 A490P Disease Disease P49748 L17F Neutral Neutral P49748 K299N Disease Disease P49748 R456H Disease Neutral P49748 R450H Disease Disease P49748 A213P Disease Disease P49748 R469Q Disease Disease P49748 T158N Disease Neutral P49748 R453Q Disease Disease P49748 K247T Disease Disease P49748 M352V Disease Neutral P49748 G43D Disease Neutral P49748 E534K Disease Neutral P49748 Q159R Disease Neutral P49748 R366H Disease Disease P49748 E218K Disease Disease P49748 K247E Disease Disease P49748 A359S Neutral Neutral P49748 R615Q Disease Neutral P49748 T260M Disease Neutral P49748 D405H Disease Disease P49748 G463E Disease Disease Q8IWL8 Q7R Neutral Neutral P28069 P24L Disease Neutral P28069 R143Q Disease Disease P28069 E174G Disease Disease P28069 W193R Disease Disease P28069 D227Y Neutral Disease P28069 R271W Disease Disease P28069 F135C Disease Disease P28069 Q4R Neutral Disease P28069 P239S Disease Disease P28069 A158P Disease Disease Q8N4U5 A82S Neutral Neutral Q9NUJ3 H109Q Neutral Disease Q8N4U5 D261N Neutral Neutral Q9NUJ3 K178R Neutral Neutral Q8N4U5 A41T Neutral Neutral Q8WWU5 R429Q Neutral Disease Q8WWU5 G253A Neutral Neutral O60294 R141S Neutral Neutral O60294 V67L Neutral Neutral O60294 T518A Neutral Neutral O60294 C149Y Neutral Neutral P33993 G473S Neutral Disease P33993 R114Q Neutral Neutral P33993 N144S Neutral Neutral Q64LD2 K59R Neutral Neutral Q64LD2 H149R Neutral Neutral Q64LD2 W88R Neutral Neutral Q96T59 R24Q Neutral Neutral Q9NRM6 N458S Neutral Neutral Q9NRM6 I451T Neutral Neutral Q9NRM6 F278L Neutral Neutral Q9NRM6 C499R Neutral Disease Q8IWN7 P2279L Neutral Neutral Q8IWN7 P44A Neutral Neutral Q8IWN7 G2149V Neutral Neutral Q8IWN7 A1563V Neutral Neutral Q8IWN7 E795K Neutral Neutral Q8IWN7 P792L Neutral Neutral Q8IWN7 A1789V Neutral Neutral Q8IWN7 R136H Neutral Neutral Q8IWN7 R56C Neutral Disease Q8IWN7 P1575R Neutral Neutral Q8IWN7 E2220K Neutral Neutral Q8IWN7 E1324G Neutral Neutral Q8IWN7 S1585L Neutral Neutral Q8IWN7 G2322E Neutral Neutral Q8IWN7 R860W Neutral Neutral Q8IWN7 H2415R Neutral Neutral Q8IWN7 G1420E Neutral Neutral Q8IWN7 E2026A Neutral Neutral Q8IWN7 A1285S Neutral Neutral Q8IWN7 A624T Neutral Neutral Q8IWN7 G1335R Neutral Neutral Q8IWN7 A2034T Neutral Neutral Q8IWN7 G2365R Neutral Neutral Q8IWN7 D1969V Neutral Neutral Q8IWN7 W1146R Neutral Neutral Q8IWN7 A487V Neutral Neutral Q8IWN7 T112S Neutral Neutral Q8IWN7 G1319A Neutral Neutral Q8IWN7 K2251E Neutral Neutral Q8IWN7 G1896D Neutral Neutral Q8IWN7 Q2168H Neutral Neutral O75899 Y628F Neutral Neutral O75899 T869A Neutral Neutral Q13127 Q762K Neutral Neutral Q13127 P797L Neutral Neutral Q13127 V626I Neutral Neutral Q13127 E692D Neutral Neutral Q96Q89 E490D Neutral Neutral Q96Q89 N756I Neutral Neutral Q96Q89 H789L Neutral Neutral Q96Q89 R1177C Neutral Neutral Q96Q89 D1011E Neutral Neutral Q96Q89 I1789V Neutral Neutral Q96Q89 E1127Q Neutral Neutral Q96Q89 A50G Neutral Neutral Q96Q89 N1219S Neutral Neutral Q96Q80 A211V Neutral Neutral Q96PI1 P45S Neutral Neutral Q7Z3E1 R406S Neutral Neutral Q8TCU6 S1559T Neutral Neutral Q8TCU6 V1240I Neutral Neutral Q8TCU6 K1340E Neutral Neutral P41159 V110M Neutral Neutral P41159 V94M Neutral Neutral Q6S5H4 M43V Neutral Neutral Q6S5H4 Q286E Neutral Neutral Q86YR6 S113G Neutral Neutral Q6S5H4 A568V Neutral Neutral Q6S5H4 M535K Neutral Neutral Q6S5H4 C68R Neutral Disease Q6S5H4 H30D Neutral Disease Q6S5H4 N88D Neutral Neutral Q6S5H4 C64W Neutral Neutral Q6S5H4 K511E Neutral Neutral Q6S5H4 T77K Neutral Neutral Q86YR6 V135I Neutral Neutral Q9ULI3 V980L Neutral Neutral Q9ULI3 F602S Neutral Neutral Q9ULI3 M1039T Neutral Neutral P55773 M106V Neutral Neutral P51671 A23T Neutral Neutral Q99616 A5S Neutral Neutral P80075 K69Q Neutral Neutral Q16663 I24T Neutral Neutral Q5VST6 Q169K Neutral Disease Q9Y2E5 V446M Neutral Neutral Q9Y2E5 S541N Neutral Neutral Q9Y2E5 V320M Neutral Neutral Q9Y2E5 P243Q Neutral Neutral Q6NY19 D288Y Neutral Neutral Q6NY19 R359H Neutral Neutral Q6NY19 A485T Neutral Neutral Q9H8X3 S27C Neutral Neutral Q9H8X3 K119R Neutral Neutral Q9H8X3 W91R Neutral Disease Q9Y6I7 L16S Neutral Neutral Q8TD07 Y82N Neutral Neutral Q8TD07 R12H Neutral Neutral Q8TD07 R128H Neutral Neutral Q8TD07 V237L Neutral Neutral Q9Y5Q5 Y13C Neutral Neutral Q9Y5Q5 R525H Neutral Neutral P11717 I1908M Neutral Neutral P11717 A724T Neutral Neutral P11717 G604S Neutral Neutral P11717 G231D Neutral Disease P11717 A2459V Neutral Neutral P11717 R1335H Neutral Neutral P11717 K512Q Neutral Neutral P11717 G856S Neutral Neutral P11717 T1107M Neutral Neutral P11717 D273G Neutral Neutral P11717 L817V Neutral Disease P11717 G1315E Neutral Disease P11717 G1860D Neutral Disease P11717 R1832H Neutral Neutral P11717 G1619R Neutral Neutral P11717 V1124I Neutral Neutral P11717 R91H Neutral Neutral P11717 P203L Neutral Neutral P11717 L252V Neutral Neutral P11717 R529Q Neutral Neutral P11717 T1184S Neutral Neutral P11717 N2020S Neutral Neutral Q16659 L290V Neutral Neutral Q3SXY7 M376T Neutral Neutral Q3SXY7 M209L Neutral Neutral Q3SXY7 T359A Neutral Neutral Q86WZ0 V613A Neutral Neutral Q86WZ0 L587H Neutral Disease Q86WZ0 W596G Neutral Disease Q7Z4N8 D400N Neutral Neutral Q9H1B5 T801R Neutral Neutral Q9H1B5 R305T Neutral Neutral P53370 R209Q Neutral Disease Q8TCW7 T197A Neutral Neutral Q8TCW7 N29S Neutral Neutral Q8TCW7 I12F Neutral Neutral P10721 C691S Neutral Disease P10721 F584L Disease Disease P10721 V559D Disease Disease P10721 L656P Disease Disease P10721 G812V Disease Disease P10721 R791G Disease Disease P10721 D816V Disease Disease P10721 T847P Disease Disease P10721 V532I Neutral Neutral P10721 G601R Disease Disease P10721 R796G Disease Disease P10721 F584C Disease Disease P10721 M541L Neutral Neutral P10721 G664R Disease Disease P10721 V559A Disease Neutral P10721 E583K Disease Disease P10721 K550I Disease Disease P10721 D816Y Disease Disease P10721 S715N Neutral Neutral Q24JP5 R699H Neutral Neutral Q24JP5 A969V Neutral Neutral Q7RTY7 S672F Neutral Disease Q7RTY7 W228G Neutral Neutral Q7RTY7 K330E Neutral Neutral Q7RTY7 G754R Neutral Disease Q7RTY7 P934S Neutral Neutral Q7RTY7 R133C Neutral Neutral Q7RTY7 I444T Neutral Neutral Q7RTY7 P881A Neutral Neutral Q7Z614 P35L Neutral Neutral P05112 C27R Neutral Disease Q9P2D3 S1601P Neutral Disease P56696 G321S Disease Disease P56696 W276S Disease Disease P56696 G285C Disease Disease P56696 L274H Disease Disease P56696 G285S Disease Disease P56696 L281S Disease Disease Q9BRQ3 R260Q Neutral Neutral Q9BRQ3 G36C Neutral Neutral Q9BRQ3 P263L Neutral Neutral P06276 Y61C Disease Disease P06276 D98G Disease Neutral P06276 F446S Disease Disease P23141 S75N Neutral Neutral P23141 D203E Neutral Neutral Q6NT32 H344Q Neutral Disease P22303 P135A Neutral Disease P06276 P128S Disease Disease P22303 R34Q Neutral Neutral P06276 G143D Disease Disease P06276 A229T Disease Disease P06276 T52M Disease Neutral P06276 E488K Disease Disease P23141 R199H Neutral Disease P06276 Q546L Disease Neutral P06276 L335P Disease Disease P06276 G393R Disease Disease Q6NT32 D537E Neutral Neutral P06276 E283D Neutral Neutral P06276 R543C Disease Disease O00748 R34W Neutral Disease P06276 D198E Disease Disease Q6NT32 G499R Neutral Disease P06276 N124Y Disease Disease P22303 H353N Neutral Neutral P06276 F56I Disease Neutral P06276 T271M Disease Neutral P06276 L358I Disease Neutral P06276 E525V Disease Disease P06276 T278P Disease Neutral P06276 W499R Disease Disease P06276 L153F Disease Neutral P06276 D98H Disease Disease P06276 S226G Disease Disease Q6NT32 E261K Neutral Disease P06276 F502L Disease Disease P06276 R414C Disease Disease P06276 A567T Disease Neutral P22303 V333E Neutral Disease P06276 Y156C Disease Disease P06276 V170M Disease Disease P06276 P65S Disease Disease P06276 A356D Disease Disease P06276 A227V Disease Disease P06276 K295R Disease Neutral Q6NT32 R71Q Neutral Disease P06276 G418V Disease Neutral O00748 R206H Neutral Disease Q14314 G53E Neutral Neutral Q96CB5 S148F Neutral Neutral Q96CB5 Q131R Neutral Neutral Q8N3D4 D569V Neutral Neutral Q8N3D4 T648I Neutral Neutral Q8N3D4 T599I Neutral Neutral Q8N3D4 R307Q Neutral Neutral Q8N3D4 V538G Neutral Neutral P42357 R322P Disease Disease P42357 P259L Disease Disease P42357 V439I Neutral Neutral P42357 R208L Disease Disease P42357 R206T Disease Neutral Q8N4B4 P10S Neutral Neutral Q8N4B4 I363M Neutral Neutral Q8N4B4 L231F Neutral Neutral Q8IU54 N188D Neutral Neutral Q16647 F171L Neutral Neutral Q16647 R379S Neutral Disease P22680 N233S Neutral Neutral Q16647 P38L Neutral Disease Q16647 E154A Neutral Neutral Q16647 P500S Neutral Neutral P22680 F100S Neutral Disease Q16647 S118R Neutral Neutral Q9UNU6 R234H Neutral Neutral P22680 D347N Neutral Neutral Q16647 R236C Neutral Neutral Q9BYG7 T134A Neutral Neutral Q9BYG7 R39S Neutral Neutral Q2M296 R315G Neutral Neutral Q2M296 L45V Neutral Neutral Q2M296 S296C Neutral Neutral Q01196 S433R Neutral Disease Q01196 R139Q Disease Disease Q01196 S431R Neutral Disease Q01196 R174Q Disease Disease P98153 V473A Neutral Neutral O94856 T159M Neutral Neutral Q63ZY6 A90V Neutral Neutral Q63ZY6 K303R Neutral Neutral Q63ZY6 C272R Neutral Neutral Q63ZY6 W47S Neutral Disease P10586 Y440C Neutral Disease P10586 D552N Neutral Neutral Q8WXG6 L1040F Neutral Neutral Q8WXG6 P696T Neutral Neutral Q8WXG6 V751M Neutral Neutral Q8WXG6 R968G Neutral Disease P29972 G165D Neutral Disease P09466 Q126K Neutral Neutral O14830 S120R Neutral Disease Q9UBR4 Y111C Disease Disease P35232 V88A Disease Disease P35232 R105H Disease Neutral O75665 S435R Disease Neutral O75665 A79T Disease Disease O75665 S74F Disease Neutral O43708 K32E Neutral Neutral O43708 T82M Neutral Disease O43708 R42G Neutral Neutral O43708 N133H Neutral Neutral Q16572 R11Q Neutral Neutral Q16572 A13P Neutral Neutral Q16572 E520A Neutral Neutral Q16572 R29W Neutral Disease Q9BYC5 T267K Neutral Neutral Q6ZN84 Y449C Neutral Neutral Q9Y448 P92S Neutral Neutral Q9Y448 R75L Neutral Disease Q9Y448 A40E Neutral Disease Q15125 R110Q Disease Disease Q15125 R147H Disease Disease Q15125 R147G Disease Disease Q15125 E80K Disease Disease Q99985 V337M Neutral Disease Q13214 T415I Disease Neutral Q9NS98 I232T Neutral Disease Q13275 A474G Neutral Disease Q13275 L503M Neutral Neutral O95025 K701Q Neutral Neutral Q13214 D397H Disease Disease Q13214 R348C Disease Disease Q9UBT6 I612V Neutral Neutral Q9UBT6 S832N Neutral Neutral Q9UBT6 T595I Neutral Neutral O00443 T1415A Neutral Neutral P00390 I261V Neutral Neutral P00390 P314H Neutral Disease P00390 E297D Neutral Neutral P00390 G232S Neutral Disease P00390 R153C Neutral Neutral O75600 R39C Neutral Disease Q9BZD4 S229L Neutral Neutral Q9BZD4 S239R Neutral Neutral Q9H9Y4 Q227R Neutral Neutral Q9H9Y4 R264G Neutral Neutral A2IDD5 W252R Neutral Neutral Q92817 Q433R Neutral Neutral Q92817 N49S Neutral Neutral P26842 A59T Neutral Neutral A6NL08 A235D Neutral Disease A6NCV1 R120C Neutral Disease Q8NGJ5 A207V Neutral Neutral Q8NG98 T133M Neutral Disease Q9H209 L246F Neutral Disease Q96KK4 R89S Neutral Disease A6NMS3 I206V Neutral Neutral Q8NH55 L234P Neutral Disease Q8NGF8 T237N Neutral Disease Q8NGN3 V195E Neutral Neutral A6NKK0 S230T Neutral Disease Q8NGK5 S305R Neutral Neutral Q8NGR8 T27P Neutral Disease Q8N162 Y169C Neutral Neutral O60404 R7S Neutral Neutral Q8NGY5 Q261R Neutral Neutral Q8NGC2 V118M Neutral Neutral A6NM03 R87L Neutral Neutral Q8NGG5 M21V Neutral Neutral Q8N146 I201V Neutral Neutral A6NF89 T190I Neutral Disease Q9P1Q5 V233M Neutral Neutral Q8NGS4 F18S Neutral Neutral Q8NG75 S164G Neutral Neutral Q8NH49 P282S Neutral Disease A6NMU1 C277R Neutral Disease Q8NG98 H131Q Neutral Disease P30954 M112I Neutral Disease Q8NH51 I275M Neutral Neutral Q8NGJ7 M288T Neutral Disease A6NM03 R299G Neutral Neutral Q8NGI8 L289F Neutral Disease Q8NGK3 R302C Neutral Disease Q8NGI7 Q123R Neutral Neutral A6NIJ9 L181P Neutral Neutral Q8NGS6 K263T Neutral Neutral A6NJZ3 L13Q Neutral Disease Q8NGY5 R293H Neutral Disease Q8NGL4 C62Y Neutral Neutral Q8NG99 F281V Neutral Neutral Q8NG98 D52G Neutral Disease Q9Y585 W293C Neutral Disease Q8NGC7 R146H Neutral Neutral Q9GZM6 R122H Neutral Disease Q8NH60 I128V Neutral Neutral Q8IXE1 C260R Neutral Neutral Q9GZK4 D63N Neutral Neutral Q8N0Y5 K139N Neutral Neutral A6NH00 R305W Neutral Disease O60403 S171F Neutral Disease Q8NGE3 P88L Neutral Neutral Q8NGK1 Y125S Neutral Disease O76001 I261M Neutral Neutral Q8NGK5 S9L Neutral Neutral Q8NH51 L122R Neutral Neutral Q8NG98 S75C Neutral Neutral Q8NGJ1 M263T Neutral Neutral A6NGY5 D301Y Neutral Neutral Q8NG98 C139Y Neutral Disease Q8NGH9 F257L Neutral Neutral Q8NH49 D246N Neutral Neutral Q8NGJ1 S151T Neutral Neutral Q96KK4 F60L Neutral Disease Q8NGY2 L156V Neutral Neutral Q9H344 T134A Neutral Neutral Q8N628 P67S Neutral Neutral O95007 R143C Neutral Disease Q8N148 V295A Neutral Disease Q9H207 K41M Neutral Neutral O60431 F211L Neutral Neutral Q8NGZ5 P24A Neutral Disease Q8NGP3 K270R Neutral Disease Q8NGG5 A84T Neutral Neutral P58173 Q270R Neutral Neutral Q8NGS4 F94S Neutral Disease Q15617 A247V Neutral Disease Q7Z3T1 M275T Neutral Neutral Q8NGC7 I107T Neutral Neutral Q8NH43 M101K Neutral Disease Q9NZP5 M200I Neutral Neutral Q8NH59 T146I Neutral Neutral Q8N127 R122L Neutral Disease A6ND48 D50N Neutral Disease Q8NGJ0 I52V Neutral Neutral Q96RD1 H165D Neutral Neutral Q8N146 R295K Neutral Neutral Q8NGE1 I37V Neutral Neutral Q8NGK2 T139I Neutral Disease Q9UGF5 M7T Neutral Neutral Q8NH43 S93F Neutral Disease Q8NGH9 R228H Neutral Disease Q7Z3T1 C169S Neutral Disease Q8N0Y5 I124V Neutral Neutral Q9Y4A9 G16R Neutral Disease Q8NH64 V196A Neutral Disease Q9Y3N9 M81V Neutral Disease Q8NGL4 R236L Neutral Disease Q8NGI2 I218N Neutral Neutral O76099 S210P Neutral Neutral Q8NGE0 Y279H Neutral Disease O76002 H74Y Neutral Neutral A6ND48 S170N Neutral Neutral Q8N628 T19A Neutral Neutral Q8NGM9 F205S Neutral Neutral Q8NGJ1 E11Q Neutral Disease Q8NGP2 G36V Neutral Neutral Q8NGL2 S287P Neutral Neutral Q9Y3N9 D296N Neutral Disease A6NH00 T179A Neutral Neutral Q8NGL4 R124H Neutral Disease Q9H346 R304W Neutral Disease Q8N148 R269K Neutral Neutral O76099 V126I Neutral Neutral Q8NGJ1 F102S Neutral Disease Q8NG98 A279D Neutral Disease Q8NGL3 S249A Neutral Neutral Q8NH60 L141Q Neutral Neutral Q8NH87 V117M Neutral Neutral O95006 T170A Neutral Neutral Q8NGS8 I282V Neutral Neutral O95006 Y278H Neutral Disease O95918 F30I Neutral Neutral Q8NGH9 F49L Neutral Neutral Q96RD1 C130Y Neutral Neutral A6NGY5 R74M Neutral Neutral Q8NH18 M136I Neutral Disease Q8NH51 V173I Neutral Neutral Q8NGR3 W271R Neutral Neutral Q8NH43 G109S Neutral Neutral Q8NGY2 I159F Neutral Neutral Q8NH43 M40V Neutral Neutral Q8NGS8 F32L Neutral Neutral Q8NGZ5 V120L Neutral Neutral Q8NG98 M136I Neutral Disease Q8NGS4 T254M Neutral Disease Q8NGN6 T5S Neutral Neutral Q8NGM9 R133K Neutral Neutral A6NGY5 F73S Neutral Neutral Q8NGL1 V118M Neutral Neutral Q8NH49 P165L Neutral Disease Q8NG98 S84N Neutral Neutral Q9GZK7 A165T Neutral Neutral A6NHA9 S240F Neutral Disease A6NMU1 Y180S Neutral Neutral Q8NGY2 R6Q Neutral Neutral Q8NGN4 Q172R Neutral Neutral Q8NH87 T83I Neutral Disease O60404 S293N Neutral Disease Q8NGF8 C63Y Neutral Disease Q8NGI2 I106T Neutral Disease Q8NGA0 Y252C Neutral Disease Q8NGH9 R184M Neutral Neutral Q8NH70 L188I Neutral Neutral Q9Y5P0 I36V Neutral Neutral Q8NGT7 A223T Neutral Neutral Q8NGI4 F197L Neutral Neutral O60404 L14I Neutral Disease Q8NG95 M29V Neutral Neutral Q8NH60 V226I Neutral Neutral O43749 F75S Neutral Neutral Q9UGF5 V278M Neutral Neutral Q8NH85 A274V Neutral Neutral Q9NZP2 P181A Neutral Disease Q8NH93 V106A Neutral Neutral Q8NGF7 L80I Neutral Disease Q8NH53 F247I Neutral Neutral Q8NGJ8 I57N Neutral Disease P34982 R25Q Neutral Neutral Q9H346 I251T Neutral Neutral Q8NGC7 C259R Neutral Disease O95221 S294N Neutral Neutral Q9GZK6 L14I Neutral Neutral Q96RC9 Y131H Neutral Disease Q8NH87 Y112C Neutral Disease Q8NGP2 M114L Neutral Neutral Q8NH72 I133T Neutral Neutral Q8NH69 A163P Neutral Disease Q7Z3T1 V190I Neutral Neutral O76002 A146V Neutral Neutral A6NKK0 I153L Neutral Disease Q8NGM9 R298K Neutral Neutral Q8NH85 C122R Neutral Neutral Q8NGD1 V135L Neutral Neutral Q8IXE1 N191D Neutral Neutral A6NKK0 T181I Neutral Neutral A6NCV1 L61F Neutral Disease Q8NGX0 F117L Neutral Neutral Q9Y585 R260C Neutral Neutral Q8NGC7 S7Y Neutral Neutral Q8NGM9 F200L Neutral Neutral Q8NGZ5 L167P Neutral Disease A6NCV1 Y75C Neutral Neutral A6ND48 V36A Neutral Neutral O95918 A48V Neutral Neutral Q96KK4 M100V Neutral Neutral Q7Z3T1 E196D Neutral Neutral P30954 I62M Neutral Neutral Q96R67 V283L Neutral Neutral Q8NGV0 V200L Neutral Neutral Q8NGL9 T76A Neutral Neutral Q96KK4 M310R Neutral Disease Q9H344 R151P Neutral Disease Q8NGN6 T136S Neutral Neutral Q8NGL0 M81R Neutral Disease Q9H344 R122C Neutral Disease Q8NH55 D209G Neutral Disease O95918 T220A Neutral Neutral Q8NGI0 H264R Neutral Disease Q8NH59 V211M Neutral Neutral Q8NGA5 N100K Neutral Neutral Q8NGE3 V200M Neutral Neutral Q9NZP0 A234S Neutral Disease Q9H208 I240T Neutral Neutral A6NHG9 Y189C Neutral Neutral P47881 R125Q Neutral Disease Q8NG98 L292M Neutral Disease Q96KK4 R121C Neutral Disease Q8NGN3 R235G Neutral Disease A6NKK0 S148T Neutral Neutral A6NGY5 H232R Neutral Neutral A6NMU1 D87G Neutral Neutral Q9H209 R221H Neutral Neutral Q8NGJ7 G59E Neutral Neutral O76002 A218T Neutral Neutral Q8NGJ5 T196I Neutral Neutral Q9H346 D213E Neutral Disease Q8NGJ1 D96G Neutral Neutral A6NDH6 V108I Neutral Neutral P30953 A143T Neutral Neutral Q8NGJ1 D111A Neutral Disease Q8N127 Y310C Neutral Neutral Q8NH93 N121D Neutral Neutral O60412 T118M Neutral Neutral Q8NG98 C139R Neutral Neutral Q9H343 V164L Neutral Neutral A6NKK0 V150I Neutral Neutral Q9Y5P0 M147T Neutral Neutral Q8NH87 C53R Neutral Neutral A6NM03 Y28C Neutral Disease Q96KK4 F161L Neutral Neutral Q96KK4 P160S Neutral Neutral Q8N146 P137S Neutral Neutral A6NHA9 C252Y Neutral Disease Q8NGJ8 L178R Neutral Neutral O60404 R54H Neutral Neutral Q8NH85 F184L Neutral Neutral O76001 R226Q Neutral Neutral Q8NH87 F61V Neutral Disease Q8NGN4 S136T Neutral Neutral Q8NGC7 L32V Neutral Disease Q8NGM9 L55R Neutral Disease Q8NGJ6 R267G Neutral Disease Q8NGT0 T91S Neutral Neutral Q9H346 R154C Neutral Disease A6NDH6 S148T Neutral Neutral Q96RD1 T222I Neutral Disease A6NJZ3 T222A Neutral Neutral Q8NH54 M51T Neutral Neutral Q8NGD3 R319K Neutral Neutral Q8NH90 M92I Neutral Neutral Q9GZK3 Q234R Neutral Neutral Q8NGZ4 V258M Neutral Neutral A6NHG9 G64R Neutral Disease Q8NH43 D2N Neutral Neutral A6NH00 M197R Neutral Disease Q8NH85 I7T Neutral Neutral Q8NGG4 E22V Neutral Neutral Q8NGK6 T41I Neutral Neutral Q8NH83 N6S Neutral Disease Q8NGK0 E96Q Neutral Disease Q9H208 K258T Neutral Neutral Q8NH43 R52S Neutral Neutral Q9Y585 G256C Neutral Neutral Q8NGJ0 D183N Neutral Disease Q8NH59 R178H Neutral Neutral Q8N148 S237F Neutral Disease Q8NGC7 Y236H Neutral Disease Q8NGS4 M101V Neutral Neutral O60431 I292T Neutral Disease Q15612 I163M Neutral Neutral Q8NH79 T190N Neutral Disease Q8NGM9 I92V Neutral Neutral Q96RD1 V246I Neutral Disease Q8NH69 R189C Neutral Neutral Q8TCB6 S10N Neutral Disease Q8NH70 K303M Neutral Neutral O60431 Y252S Neutral Disease A6NCV1 R2G Neutral Disease A6NH00 A221S Neutral Neutral O76001 T113A Neutral Neutral Q96KK4 V246M Neutral Disease A6NDH6 T167S Neutral Neutral Q8NGI9 P172L Neutral Disease Q9H209 R262Q Neutral Neutral Q8NGA5 H144R Neutral Neutral Q8NGK3 R124C Neutral Disease Q9H346 Y221F Neutral Disease Q96KK4 P174Q Neutral Neutral Q8NGS8 M258T Neutral Disease A6NET4 G44D Neutral Disease Q96RB7 S171N Neutral Neutral Q8NG98 L162P Neutral Disease O95918 F30S Neutral Neutral Q8NGI0 S249A Neutral Neutral Q8IXE1 S234T Neutral Neutral A6NM03 R54P Neutral Disease Q8NH59 C153R Neutral Neutral Q96KK4 L255I Neutral Neutral Q8NGS8 C189Y Neutral Disease Q8NH55 T165I Neutral Neutral Q8NGY5 I194T Neutral Neutral O60404 V224M Neutral Neutral Q8NG92 Y266S Neutral Neutral A6NH00 G39S Neutral Neutral Q8NH64 M81T Neutral Neutral Q8NGC2 Q234R Neutral Neutral Q8NH55 E309K Neutral Neutral Q8NGA0 W141C Neutral Neutral Q13606 F76S Neutral Neutral Q8NGL3 L290P Neutral Disease Q9H344 R263H Neutral Disease Q8NH76 P277S Neutral Neutral Q8NGK9 A156T Neutral Neutral Q8NGH9 V176I Neutral Neutral Q9P1Q5 P285S Neutral Disease Q8NH90 G4V Neutral Disease A6NH00 W49R Neutral Disease Q9H208 H207R Neutral Neutral Q8NGJ8 Q60E Neutral Neutral O60431 P139R Neutral Neutral Q8N162 H120Y Neutral Neutral A6NL08 L141F Neutral Neutral Q96KK4 P57S Neutral Disease Q96KK4 R138W Neutral Disease O76100 Q183E Neutral Neutral Q8NH60 A77T Neutral Neutral A6NCV1 G86D Neutral Disease Q7Z3T1 M272K Neutral Neutral Q8NGR8 R211P Neutral Disease Q8NGQ4 E12D Neutral Neutral Q8NGL2 I46F Neutral Disease Q96RB7 V280L Neutral Disease O76002 A111T Neutral Neutral Q8NH53 R167C Neutral Disease Q9NZP2 L209P Neutral Disease A6NHA9 K288R Neutral Neutral A6NGY5 T20A Neutral Neutral Q8NGG5 P27T Neutral Disease Q8NGY5 A10T Neutral Neutral Q8NGZ6 F215L Neutral Neutral Q8NH87 A259S Neutral Neutral Q8NGC9 T301S Neutral Neutral Q7Z3T1 R179C Neutral Neutral O95006 A98V Neutral Neutral Q8NGY1 N294T Neutral Disease O76001 V228I Neutral Neutral Q8NGM9 L283P Neutral Neutral Q8NGS8 M290T Neutral Disease Q8NH64 E8K Neutral Disease Q8NGJ6 T288M Neutral Neutral Q8NGT0 E24D Neutral Neutral Q8NGZ5 R236G Neutral Neutral Q8NGD0 T116I Neutral Neutral Q8NGC7 L195F Neutral Neutral Q8NGS7 A19D Neutral Neutral Q96R28 A237T Neutral Disease Q9H343 A252S Neutral Neutral Q8WZ84 L194P Neutral Disease P35555 C1053R Disease Disease Q75N90 V1326I Neutral Neutral P35555 R1530C Disease Disease P35555 C1770F Disease Disease P35555 N2223H Disease Disease P35555 E1073K Disease Neutral P35556 C1252W Disease Neutral P35555 D2127E Disease Neutral P35555 R545C Disease Disease P35555 C711Y Disease Disease Q75N90 L1904P Neutral Disease P35555 C862R Disease Disease P35555 E1200G Disease Neutral Q75N90 S1293N Neutral Neutral P35555 C129Y Disease Disease P35555 Y1219C Disease Disease P35555 E913G Disease Disease P35555 C1928G Disease Neutral P35556 V964I Neutral Neutral P35555 C2489R Disease Disease P35555 T1887I Disease Neutral P35555 C166F Disease Disease P35555 C1265R Disease Disease P35555 C1074R Disease Disease P35555 C652S Disease Disease Q75N90 P1958H Neutral Neutral P35555 C781Y Disease Disease P35555 C2038Y Disease Disease P35555 D723A Disease Neutral P35555 C890R Disease Disease P35555 C123Y Disease Disease P35555 C2307S Disease Disease P35555 C1284G Disease Neutral P35555 D654N Disease Disease P35555 C1339Y Disease Neutral P35555 C921G Disease Disease P35555 C1876Y Disease Disease P35555 C1513R Disease Disease Q75N90 S1614G Neutral Neutral Q75N90 R1806Q Neutral Neutral P35555 C628K Disease Disease P35555 R1137P Disease Neutral P35555 R1790P Disease Disease P35555 I1048T Disease Neutral P35555 A705T Disease Neutral P35555 T2101M Neutral Neutral P35555 C776G Disease Neutral P35555 C2571R Disease Disease P35555 C1928R Disease Neutral P35555 S681Y Disease Neutral P35555 P1837S Disease Neutral P35555 Y746C Disease Neutral P35555 N2624K Disease Disease P35555 C2251R Disease Disease P35555 C504F Disease Disease P35555 P2154R Disease Neutral P35555 C2511R Disease Disease P35555 C1117G Disease Disease P35555 P1148A Neutral Neutral P35555 C1791Y Disease Disease P35555 C1278S Disease Neutral P35555 C1129Y Disease Disease P35555 G592D Disease Disease P35555 D723V Disease Neutral P35555 P1424A Disease Neutral P35555 C1564Y Disease Disease P35555 R62C Disease Disease P35555 C2142Y Disease Disease P35555 C1589F Disease Disease P35555 C2111Y Disease Disease P35555 C224R Disease Disease P35555 C1971Y Disease Disease P35555 G1796E Disease Disease P35555 D1155N Disease Disease P35555 C2581F Disease Disease P35555 R1170H Disease Neutral P35555 C1044Y Disease Disease P35555 C661R Disease Disease P35555 R2335W Disease Neutral P35555 R439G Disease Disease P35555 Y20C Disease Neutral P35555 A2385T Disease Neutral P35555 C1806Y Disease Neutral P35555 C661Y Disease Disease P35555 C1055G Disease Neutral P35555 C2339Y Disease Disease P35555 I2269T Disease Disease P35555 C1833S Disease Disease P35555 G985R Disease Disease P35555 R122C Disease Disease P35555 D1113V Disease Neutral P35555 C996R Disease Disease P35555 R636I Disease Neutral P35555 C1806S Disease Neutral P35555 E2610K Disease Neutral P35555 C1998Y Disease Disease P35555 E2447K Disease Disease P35555 A2160P Disease Neutral P35555 C1249S Disease Neutral P35555 C776Y Disease Disease Q75N90 D2610E Neutral Neutral P35555 C1402R Disease Disease P35555 S115C Disease Neutral P35555 C596Y Disease Disease P35555 C734F Disease Disease P35556 E390K Disease Neutral P35555 R2726W Disease Disease P35555 H2623P Disease Neutral P35555 N1893K Disease Disease P35555 C1086W Disease Disease P35555 C1631G Disease Disease P35555 Y2629C Disease Disease P35555 G2618R Disease Neutral P35555 R627C Disease Disease P35555 N548I Disease Neutral P35555 M1576T Disease Neutral P35555 D490Y Disease Disease P35555 C2605R Disease Disease P35555 C2111R Disease Disease P35555 C2151W Disease Disease P35555 C2221F Disease Disease P35555 C1374S Disease Neutral P35555 G2627R Disease Disease P35555 Y1101C Disease Neutral P35555 G1475E Disease Disease P35555 R240C Disease Neutral P35556 C1141F Disease Disease P35555 C890G Disease Disease P35555 G985E Disease Disease P35555 C1333S Disease Neutral P35555 C587Y Disease Disease P35555 R114C Disease Disease P35555 C177R Disease Disease P35555 C1928Y Disease Neutral P35555 G560S Disease Disease P35555 C2500R Disease Disease P35555 C2406Y Disease Disease P35556 P2770S Neutral Neutral P35555 W217G Disease Disease P35555 C1153Y Disease Disease P35555 C750G Disease Neutral Q75N90 R935L Neutral Disease P35555 I1909T Disease Neutral P35555 C1242Y Disease Neutral Q75N90 N662D Neutral Neutral P35555 A1337P Disease Disease P35555 C1223Y Disease Disease P35555 G2668C Disease Neutral P35555 R2282W Disease Neutral P35555 C2085R Disease Disease P35555 C781R Disease Disease P35555 C1977Y Disease Disease P35555 C1663R Disease Disease P35555 C2442W Disease Disease P35555 C832Y Disease Disease P35555 C166S Disease Disease P35555 C2221S Disease Disease Q75N90 G119A Neutral Neutral P35555 C1055W Disease Disease P35555 V984I Disease Neutral P35555 C2099W Disease Disease P35555 C2258R Disease Neutral P35555 Y2474C Disease Disease P35555 C1610G Disease Disease P35556 D1114H Disease Neutral P35555 C89F Disease Disease P35555 C111R Disease Disease P35555 G1475S Disease Disease P35555 E1325Q Disease Neutral P35555 C570Y Disease Disease P35555 N2144S Disease Neutral P35555 G1058D Disease Disease P35555 C1793W Disease Disease P35555 K1043R Disease Neutral P35555 C1117Y Disease Disease P35555 C748Y Disease Neutral P35555 C2663S Disease Disease P35555 K1023N Disease Neutral P35555 W366C Disease Disease P35555 C683R Disease Disease Q75N90 V938F Neutral Disease P35555 C1429S Disease Disease P35556 C1252Y Disease Disease P35556 C1433S Disease Disease P35555 C908R Disease Disease P35555 C1663Y Disease Disease P35555 Y635C Disease Disease P35555 C1564F Disease Disease P35555 C2605Y Disease Disease Q75N90 R473Q Neutral Neutral P35555 C685W Disease Disease P35555 P1424S Disease Neutral P35555 N1382S Disease Neutral P35555 C926R Disease Disease P35555 C476G Disease Disease P35555 E2570K Disease Neutral P35555 C1791R Disease Disease P35555 C2500Y Disease Disease P35555 A27T Neutral Neutral P35555 C2652G Disease Disease Q75N90 N1869K Neutral Neutral P35555 C1389R Disease Disease P35555 C816S Disease Disease P35555 G2536R Disease Disease P35555 C598W Disease Disease P35555 C2221G Disease Disease P35555 C1055Y Disease Neutral P35555 I2585T Disease Neutral P35556 P2427T Neutral Disease P35555 E1366K Disease Neutral P35555 C1835Y Disease Disease P35555 C541Y Disease Neutral P35555 N1173K Disease Disease P35555 Y1261C Disease Neutral P35555 N1131Y Disease Disease P35555 R2680C Disease Disease P35555 C1153S Disease Disease P35555 D1404Y Disease Disease P35555 D1072G Disease Neutral P35555 C154S Disease Disease P35555 Y1261D Disease Neutral P35555 R1915S Disease Neutral P35555 C2535W Disease Disease P35555 G1013R Disease Disease P35555 C1900Y Disease Disease Q75N90 R1083W Neutral Neutral P35555 C1171W Disease Disease P35555 C1895R Disease Disease P35555 C2592S Disease Disease Q8N7X0 I310T Neutral Neutral P31751 I188V Neutral Neutral P31751 R208K Neutral Neutral P59092 C49Y Neutral Disease O15055 S662G Disease Disease Q8IZL8 T1126S Neutral Neutral P30613 G341A Disease Disease P30613 K348N Disease Disease P30613 I342F Disease Disease P30613 G458D Disease Disease P30613 G275R Disease Disease P30613 V134D Disease Disease P30613 I314T Disease Disease P30613 R163C Disease Disease P30613 G263R Disease Disease P30613 R532Q Disease Neutral P30613 A115P Disease Disease P30613 E387G Disease Disease P30613 G37E Disease Neutral P30613 A352D Disease Disease P30613 I90N Disease Disease P30613 I153T Disease Disease P30613 V552M Disease Disease P30613 R569Q Disease Disease P30613 D339H Disease Disease P30613 G364D Disease Disease P30613 A336S Disease Disease P30613 A431T Disease Disease P30613 A468G Disease Disease P30613 G222A Disease Disease P30613 R531C Disease Disease P30613 A495V Disease Disease P30613 E172Q Disease Neutral P30613 Q421K Disease Disease P30613 T408A Disease Disease P30613 T384M Disease Disease P30613 A392T Disease Disease P30613 A295V Disease Neutral P30613 R337Q Disease Disease P30613 G263W Disease Disease P30613 R86P Disease Disease P30613 R426Q Disease Disease P30613 G95R Disease Disease P30613 A394D Disease Disease P30613 S485F Disease Disease P30613 R359H Disease Disease P30613 M107T Disease Disease P30613 S130Y Disease Neutral P30613 R479H Disease Disease P30613 V335M Disease Disease P30613 R488Q Disease Disease P30613 S80P Disease Disease P30613 G557A Disease Disease P30613 A459V Disease Disease P30613 F287V Disease Disease P30613 I219T Disease Disease P30613 D293N Disease Disease P30613 E427A Disease Neutral P30613 R559G Disease Disease P30613 G332S Disease Disease P30613 R490W Disease Disease P30613 A495T Disease Disease P30613 D331N Disease Disease P30613 I357T Disease Disease P30613 A468V Disease Disease P30613 N393S Disease Disease P30613 V368F Disease Disease P30613 R359C Disease Disease P30613 D281N Disease Disease P30613 R486W Disease Disease P30613 D390N Disease Disease P30613 A394V Disease Disease P30613 T408I Disease Disease P30613 S376I Disease Disease P30613 I310N Disease Disease P30613 G341D Disease Disease P30613 N393K Disease Disease P30613 G511R Disease Disease P30613 T477A Disease Neutral P30613 R498C Disease Disease P14618 G204V Neutral Disease P30613 N361D Disease Disease P30613 D331E Disease Disease P30613 S120F Disease Disease P30613 R532W Disease Disease P30613 R337P Disease Disease P30613 V460M Disease Neutral P30613 R426W Disease Disease P30613 G111R Disease Disease P30613 G159V Disease Disease P30613 N566K Disease Disease P30613 R385W Disease Disease P30613 E315K Disease Disease P30613 R510Q Disease Disease P30613 V506I Neutral Neutral P30613 R504L Disease Disease P30613 E427D Disease Disease P30613 V288L Disease Disease P30613 R498H Disease Disease P30613 L155P Disease Disease Q8NHX9 G734E Neutral Neutral Q8NHX9 L564P Neutral Disease Q8NHX9 K376R Neutral Neutral Q9H2I8 S153F Neutral Neutral Q92834 C302Y Disease Disease Q92834 A262G Disease Disease Q92834 S76I Neutral Disease Q92834 Q184H Neutral Neutral Q92834 G215V Disease Disease Q92834 D312Y Disease Disease Q92834 G43E Disease Disease Q92834 R425K Neutral Neutral Q92834 D312N Disease Disease Q92834 I289V Disease Neutral Q92834 G267R Disease Disease Q92834 N345D Neutral Neutral Q92834 P235S Disease Disease Q92834 T99N Disease Disease Q92834 T533M Neutral Neutral Q92834 F130C Disease Neutral Q92834 C250Y Disease Disease Q92834 G436D Disease Neutral Q92834 G60V Disease Disease Q92834 G173R Disease Disease Q92834 G275S Disease Disease Q92834 G267E Disease Disease Q92834 I431V Neutral Neutral Q92834 G566E Neutral Neutral Q92834 H98Q Disease Disease Q92834 C250R Disease Disease Q92834 I75V Disease Neutral Q92834 R127G Disease Disease Q92834 E285G Disease Disease Q92834 G43R Disease Disease Q92834 G320R Disease Disease Q92834 S152L Disease Neutral Q92834 C302R Disease Disease Q14566 E35V Neutral Disease Q14566 E806K Neutral Neutral Q92521 K551T Neutral Neutral Q92521 L484S Neutral Disease Q92521 I68L Neutral Neutral Q92521 M162T Neutral Neutral Q92521 W299L Neutral Neutral Q6NX45 V147I Neutral Neutral Q6NX45 S83N Neutral Neutral Q6NX45 P65L Neutral Neutral P23352 K666M Neutral Neutral P23352 C172R Disease Disease P23352 F517L Disease Neutral P23352 S396L Disease Neutral P23352 R262P Disease Disease P23352 N267K Disease Disease P23352 R668H Neutral Neutral P23352 N304S Disease Neutral P23352 E514K Disease Neutral P23352 W571R Disease Disease P23352 C163Y Disease Disease P23352 V534I Neutral Neutral Q96G28 D243G Neutral Neutral Q96G28 I246F Neutral Neutral Q02127 K7Q Neutral Neutral P15382 S74L Disease Disease P15382 W87R Disease Disease P15382 D85N Neutral Neutral P15382 L51H Disease Disease P15382 R32H Disease Neutral P15382 T7I Disease Neutral P15382 D76N Disease Neutral P15382 R98W Disease Disease P15382 V47F Disease Neutral P15382 V109I Disease Neutral P15382 P127T Disease Neutral P15382 S38G Neutral Neutral Q8IY18 V306I Neutral Neutral Q8IY18 C308R Neutral Neutral P17927 T1408I Neutral Neutral P17927 I1615V Neutral Neutral P17927 H1850D Neutral Neutral P17927 K1590E Neutral Neutral P17927 P1827R Neutral Neutral P17927 T1408M Neutral Neutral P17927 H1208R Neutral Neutral P17927 R1601G Neutral Neutral Q8IYD8 V878L Neutral Neutral Q8IYD8 S175F Neutral Neutral Q8IYD8 P1812A Neutral Neutral Q8TE67 P356S Neutral Neutral Q8TE67 G163S Neutral Neutral Q8TE67 H293Y Neutral Neutral A2RUS2 S143N Neutral Neutral A2RUS2 Q364R Neutral Neutral Q9NQ50 R129H Neutral Neutral Q9UJ90 E114Q Neutral Neutral P28331 R241Q Neutral Disease P28331 V649F Neutral Neutral Q9BZE1 L322V Neutral Neutral Q9BZE1 C366S Neutral Neutral O14746 H412Y Neutral Neutral O14746 K902N Disease Disease O14746 A279T Neutral Neutral O14746 A1062T Neutral Neutral Q9ULF5 T87S Neutral Neutral Q96BI1 R70C Disease Neutral Q96BI1 R293Q Neutral Neutral Q96BI1 S217F Disease Neutral P49427 D227H Neutral Neutral P81133 A371V Neutral Neutral P81133 P352T Neutral Neutral P01270 S23P Disease Neutral P01270 C18R Disease Disease P46199 I556V Neutral Neutral Q8NFU7 A256V Neutral Neutral Q8NFU7 I1123M Neutral Neutral Q8NFU7 S193T Neutral Neutral Q8NFU7 N1018S Neutral Neutral Q8NFU7 D162G Neutral Neutral O43593 D1012N Disease Disease O43593 T1022A Disease Neutral O43593 V1136D Disease Disease Q99551 A294T Neutral Neutral Q96KG7 V206I Neutral Neutral Q96KG7 R1072K Neutral Neutral A2PYH4 P115S Neutral Neutral A2PYH4 V117I Neutral Neutral Q96D31 R91W Disease Disease Q96D31 S218G Neutral Neutral O43364 M196L Neutral Disease Q96FI4 D252N Neutral Neutral Q9UNA1 N417S Disease Neutral Q6P1K2 M137I Neutral Neutral Q6P1K2 Q75R Neutral Neutral Q6PD74 I132L Neutral Neutral Q9NQ90 S501A Neutral Neutral Q9NQ90 V108A Neutral Neutral Q9UIF7 G393D Disease Disease Q9UIF7 G500E Neutral Neutral Q9UIF7 L526M Neutral Neutral Q9UIF7 R531Q Neutral Neutral Q9UIF7 Y176C Disease Disease Q9UIF7 Q335H Neutral Neutral Q9UIF7 Q411R Disease Neutral Q9UIF7 V22M Neutral Neutral Q9UIF7 P402S Disease Disease Q9UIF7 S512F Neutral Neutral Q9UIF7 W128R Disease Disease Q9BQA5 V493A Neutral Neutral Q9BQA5 K352R Neutral Neutral Q9BQA5 S78C Neutral Neutral Q9BQA5 P4S Neutral Neutral P36507 F57C Disease Disease Q02750 F53S Disease Disease Q02750 Y130C Disease Disease Q96A28 D164H Neutral Neutral Q96A28 V86M Neutral Neutral Q96A28 E181K Neutral Neutral Q96A28 L127I Neutral Disease Q96NR8 T49M Disease Disease Q96NR8 S175P Disease Disease Q96NR8 R161Q Neutral Disease Q96NR8 I51N Disease Disease Q96NR8 H151D Disease Disease Q96NR8 Y226C Disease Disease Q96NR8 P230A Disease Disease Q96NR8 H151N Disease Neutral Q96NR8 L99I Disease Neutral Q8NC44 P419Q Neutral Neutral Q8NC44 R374H Neutral Neutral Q8N344 S485G Neutral Neutral Q8N344 D104N Neutral Neutral Q8N344 D68N Neutral Neutral Q8N344 P464S Neutral Neutral Q9Y4H2 G1057D Neutral Neutral Q9Y4H2 H789Y Neutral Neutral P35568 D1137N Neutral Neutral P35568 S1043Y Disease Neutral P35568 P158R Neutral Disease P35568 S892G Neutral Neutral P35568 G971R Neutral Neutral P35568 C1095Y Disease Disease Q9Y4H2 G882A Neutral Neutral P35568 A512P Neutral Disease P35568 S809F Neutral Neutral P35568 M209T Neutral Disease Q9Y4H2 G879S Neutral Neutral Q9Y4H2 V999M Neutral Neutral Q9GZV8 K244E Neutral Neutral Q96M95 A144T Neutral Neutral Q14994 V133G Neutral Neutral Q969S2 P304T Neutral Neutral Q969S2 R103W Neutral Neutral Q969S2 R257L Neutral Neutral Q969S2 T70S Neutral Neutral Q969S2 R103Q Neutral Neutral P08709 V295D Neutral Neutral P08709 A352T Neutral Neutral P08709 R413Q Neutral Neutral P08709 E445K Neutral Neutral P08709 T367S Neutral Neutral Q9H3M9 L266F Neutral Neutral Q9H3M9 G332D Neutral Neutral P54252 M212V Neutral Neutral Q07157 H1110R Neutral Neutral Q07157 N1605S Neutral Neutral Q07157 N471S Neutral Disease Q07157 I790V Neutral Neutral Q07157 D1347A Neutral Neutral Q07157 P930L Neutral Neutral O95229 A4S Neutral Neutral Q8IYL2 R352G Neutral Neutral O15389 P499A Neutral Neutral O15389 F322S Neutral Neutral O15389 M215V Neutral Neutral O15389 V72A Neutral Disease Q96IP4 T318A Neutral Neutral Q9P2K1 V660I Neutral Neutral Q9P2K1 E376A Neutral Neutral Q9NSU2 E321G Neutral Neutral Q9NSU2 V256D Disease Disease Q9NSU2 D255N Disease Neutral Q9NSU2 R169H Disease Neutral Q9NSU2 D73N Disease Disease Q9UQF2 S59N Disease Neutral Q9NZC9 I548N Disease Disease Q9NZC9 K647Q Disease Disease Q9NZC9 A468P Disease Disease Q9NZC9 R645C Disease Disease Q9NZC9 R586W Disease Disease Q9NZC9 S579L Disease Disease Q9NZC9 K647T Disease Disease Q9NZC9 R820H Disease Disease Q9NZC9 R644W Disease Disease Q9NZC9 T705I Disease Neutral Q9NZC9 R764Q Disease Disease Q96DD7 M159I Neutral Neutral P49736 E166Q Neutral Neutral P49736 G501R Neutral Disease P49736 V667M Neutral Neutral P49736 A396T Neutral Disease P49736 L135F Neutral Neutral P49736 A727T Neutral Disease P49736 D68E Neutral Neutral Q06330 P425S Neutral Disease Q06330 K291E Neutral Neutral Q06330 R419Q Neutral Neutral Q06330 A456V Neutral Neutral Q06330 D334H Neutral Neutral P08581 K1244R Disease Neutral P08581 H1106D Disease Neutral P08581 Y1230D Disease Disease P08581 E168D Neutral Neutral P08581 Y1230C Disease Disease P08581 H1094L Disease Neutral P08581 M1250I Disease Disease P08581 H1094Y Disease Neutral P08581 M1131T Disease Disease P08581 M1250T Disease Neutral P08581 R970C Neutral Neutral P08581 I316M Neutral Neutral P08581 P991S Disease Neutral P08581 P773L Disease Neutral P08581 S156L Neutral Neutral P08581 R143Q Neutral Neutral P08581 L238S Neutral Disease P08581 N375S Neutral Neutral P08581 Y1230H Disease Disease P08581 T1173I Disease Neutral P08581 D1228N Disease Disease P08581 V1220I Disease Neutral P08581 V1092I Disease Disease P08581 L1195V Disease Disease P08581 H1094R Disease Neutral P08581 D1228H Disease Disease P08581 V1188L Disease Disease P08581 A320V Neutral Disease Q8IZP7 K265R Neutral Disease Q5JT82 N156S Neutral Neutral O43612 L16R Disease Neutral Q9UHW5 V244A Neutral Disease Q9UHW5 A52V Neutral Neutral Q8TBJ5 S250W Neutral Disease Q8TBJ5 P164T Neutral Neutral O00429 S71T Neutral Neutral O00429 E426D Neutral Neutral Q9NTJ5 Y434F Neutral Neutral Q99626 S293P Neutral Neutral Q8NEK8 D185E Neutral Neutral P43694 S52F Disease Disease P43694 S377G Neutral Neutral P43694 G296S Disease Disease Q4LDE5 G332A Neutral Neutral Q4LDE5 L1330M Neutral Neutral Q4LDE5 R1956K Neutral Disease Q4LDE5 V507I Neutral Neutral Q4LDE5 M1444L Neutral Neutral Q4LDE5 I1157V Neutral Neutral Q4LDE5 P3233T Neutral Neutral Q4LDE5 I2925V Neutral Neutral Q4LDE5 Q581H Neutral Neutral Q4LDE5 I637V Neutral Neutral Q4LDE5 F3164I Neutral Neutral Q4LDE5 K899R Neutral Neutral Q4LDE5 G428S Neutral Neutral Q4LDE5 K1416Q Neutral Neutral Q4LDE5 T2610A Neutral Neutral Q4LDE5 A2753V Neutral Neutral Q4LDE5 T3562M Neutral Neutral Q4LDE5 E1813A Neutral Neutral Q4LDE5 L1651V Neutral Neutral Q9ULL4 M1535T Neutral Neutral Q9ULL4 V598I Neutral Neutral Q8N8M0 S63F Neutral Neutral Q9Y4R8 Q146R Neutral Neutral Q9Y4R8 Q674R Neutral Neutral Q9Y4R8 E7G Neutral Neutral O75712 E183K Disease Disease O75712 G12R Disease Disease O75712 R42P Disease Disease O75712 C86S Disease Disease Q9NTQ9 R103C Neutral Disease O75712 I141V Disease Neutral O75712 F137L Disease Neutral O75712 V200I Neutral Neutral O75712 R32W Neutral Disease Q9NTQ9 F137L Disease Disease O75712 G12D Disease Disease Q9NTQ9 E204A Neutral Disease Q8TBH0 R192H Neutral Disease Q8TBH0 A244T Neutral Neutral Q8TBH0 L396P Neutral Neutral Q8TBH0 R181H Neutral Neutral Q96M34 G312S Neutral Neutral Q96M34 Q193H Neutral Neutral Q96M34 D99G Neutral Neutral Q96M34 D473E Neutral Neutral Q96M34 N45T Neutral Neutral Q6ZVD7 E608D Neutral Neutral Q6ZVD7 N825I Disease Neutral Q6ZVD7 R18P Disease Neutral Q6ZVD7 Y153H Disease Neutral Q9NQT6 A24S Neutral Neutral Q9NQT6 H428L Neutral Disease Q96T68 V473M Neutral Neutral Q96T68 E117G Neutral Neutral O75363 Q24K Neutral Neutral O75363 V163A Neutral Neutral O75363 G255E Neutral Neutral O75363 S583P Neutral Neutral Q6UB98 S818N Neutral Neutral Q6UB98 K906R Neutral Neutral Q6UB98 P277A Neutral Neutral Q6UB98 S171T Neutral Neutral O15522 G16A Neutral Neutral P29965 T254M Disease Neutral P29965 G227V Disease Disease P29965 G144E Disease Disease P29965 H224Y Disease Neutral P29965 W140R Disease Disease P29965 G116S Disease Neutral P29965 A208D Disease Disease P29965 A235P Disease Neutral P29965 G116R Disease Neutral P29965 K143T Disease Neutral P29965 G226A Disease Neutral P29965 G219R Neutral Neutral P29965 L258S Disease Neutral P29965 V126A Disease Neutral P29965 T147N Disease Neutral P29965 A123E Disease Disease P29965 V126D Disease Neutral P29965 W140G Disease Disease P29965 T176I Disease Disease P29965 G38R Disease Disease P29965 G257S Disease Neutral P29965 W140C Disease Disease P29965 T211N Disease Neutral P29965 L231S Disease Disease P29965 H125R Disease Neutral P29965 L155P Disease Disease P29965 Q174R Disease Disease P29965 Y170C Disease Disease P29965 L195P Disease Disease P29965 A173D Disease Neutral P29965 M36R Disease Disease P29965 G257D Disease Disease P29965 V237E Disease Disease Q9H0C3 R90H Neutral Neutral Q6UX27 G163S Neutral Neutral Q9BRR8 H724R Neutral Neutral Q9BRR8 E909K Neutral Neutral Q9BRR8 L476P Neutral Disease Q9BRR8 L728S Neutral Neutral Q96KK3 I489V Neutral Neutral Q16254 T293P Neutral Neutral P54577 G41R Disease Disease P54577 E196K Disease Disease P54577 Q170H Neutral Disease P04049 L613V Disease Neutral P04049 S257L Disease Disease P04049 T491I Disease Disease P04049 V263A Disease Neutral P04049 S259F Disease Disease P04049 D486G Disease Disease P04049 R256S Disease Disease P04049 D486N Disease Disease P04049 P261A Disease Disease P04049 T491R Disease Neutral P04049 T260R Disease Neutral P04049 S612T Disease Neutral P04049 P261L Disease Disease P04049 P261S Disease Disease Q5VUB5 P465S Neutral Neutral Q8NA03 L411F Neutral Neutral Q8NA03 R354H Neutral Neutral Q8NA03 C402R Neutral Neutral Q8NA03 E374G Neutral Neutral Q8NA03 N64D Neutral Neutral Q8NA03 G528A Neutral Neutral Q9NZV7 A110T Neutral Neutral P02656 K78E Disease Neutral Q96SN8 R1045T Neutral Neutral Q96SN8 V1540L Neutral Neutral Q96SN8 E289Q Neutral Neutral Q96EW2 S64A Neutral Neutral O15360 D252G Disease Neutral O15360 L210R Disease Disease O15360 P1324L Disease Neutral O15360 D1359Y Disease Disease O15360 F1262L Disease Neutral O15360 G809D Neutral Neutral O15360 V761E Neutral Neutral O15360 Y843D Disease Disease O15360 D598N Disease Neutral O15360 R1400H Disease Disease O15360 T266A Neutral Neutral O15360 L244F Disease Neutral O15360 Q1128E Disease Neutral O15360 A1346T Disease Neutral O15360 L817P Disease Neutral O15360 R1055L Disease Disease O15360 L845P Disease Disease O15360 P739L Neutral Neutral O15360 Q869P Disease Disease O15360 T1328A Neutral Neutral O15360 H1417D Disease Neutral O15360 W1302R Disease Disease O15360 T1131A Disease Neutral O15360 H1110P Disease Disease O15360 R951W Neutral Disease O15360 A181V Disease Neutral O15360 R1055W Disease Disease O15360 S1088F Disease Neutral O15360 H492R Disease Neutral O15360 N8K Disease Neutral O15360 L660P Disease Neutral O15360 R435C Disease Disease O15360 V6D Neutral Neutral O15360 L1249P Disease Disease O15360 S858R Disease Neutral O15360 M1360I Disease Neutral O15360 R951Q Neutral Neutral O15360 V1287I Neutral Neutral O15360 G501S Neutral Neutral O15360 L1082P Disease Disease O15360 R1117G Disease Neutral O00214 V55M Neutral Neutral O00214 Y18F Neutral Neutral O00214 C35R Neutral Disease P46734 R175W Disease Disease P46734 R26T Neutral Neutral P46734 L215V Disease Neutral P17676 G195S Neutral Neutral O95140 R94W Disease Disease O95140 R94Q Disease Disease O95140 K357N Disease Disease O95140 R280H Disease Disease O95140 R364W Disease Disease O95140 Q276R Disease Disease O95140 H361Y Disease Disease O95140 L76P Disease Disease O95140 P251A Disease Disease O95140 T206I Disease Disease O95140 W740S Disease Neutral O95140 V69F Disease Neutral Q96QA5 R18Q Neutral Neutral Q96QA5 E130K Neutral Neutral Q96QA5 L128V Neutral Neutral Q9HBE5 G484S Neutral Neutral Q9HBE5 S318R Neutral Neutral Q9HBE5 R191C Neutral Neutral O00338 Y128H Neutral Disease P50225 R37Q Neutral Disease P50226 T7I Neutral Neutral P50225 R213H Neutral Disease O00338 S255A Neutral Neutral P50225 N235T Neutral Disease O43704 L145V Neutral Neutral O75897 D5E Neutral Neutral P50225 M223V Neutral Neutral Q6IMI6 M194T Neutral Disease P50225 E151D Neutral Neutral Q6IMI6 Y148C Neutral Disease P50226 T235N Neutral Neutral P49888 D22Y Neutral Disease Q6IMI6 G179R Neutral Disease Q9BQS8 A679V Neutral Neutral Q9BQS8 G321A Neutral Neutral Q9BQS8 Q250R Neutral Neutral Q9BQS8 N1001D Neutral Neutral Q9BQS8 R282H Neutral Neutral Q9BQS8 T381M Neutral Neutral Q5T4F7 G7A Neutral Neutral P15056 G469R Disease Disease P15056 D594G Disease Disease P15056 L485F Disease Disease P15056 E501K Disease Disease P15056 Q257R Disease Neutral P15056 G469E Disease Disease P15056 A246P Disease Disease P15056 L597R Disease Disease P15056 G466A Disease Disease P15056 R462I Disease Neutral P15056 F595L Disease Disease P15056 F468S Disease Disease P15056 K499E Disease Neutral P15056 G466E Disease Disease P15056 V600D Disease Disease P15056 I463S Disease Disease P15056 E586K Disease Neutral P15056 P301S Neutral Neutral P15056 G464E Disease Disease P15056 G464V Disease Disease P15056 V600E Disease Disease P15056 E501G Disease Disease P15056 K601E Disease Neutral P15056 S467A Disease Neutral P15056 G466V Disease Disease P15056 N581D Disease Disease P15056 G469A Disease Disease P15056 G596V Disease Disease Q9UP83 I365V Neutral Neutral Q9UP83 L330F Neutral Neutral Q9UP83 P558S Neutral Neutral Q8IYX3 R122W Neutral Neutral Q8IYX3 A436T Neutral Neutral Q8IYX3 R199W Neutral Disease Q8IYX3 G121R Neutral Neutral Q8IYX3 R96C Neutral Neutral P29966 A274V Neutral Neutral P29966 P250L Neutral Neutral Q9NWN3 I470N Neutral Neutral Q9NWN3 L533P Neutral Neutral Q6PID8 S2L Neutral Neutral Q6PID8 L437I Neutral Neutral Q6PID8 I274V Neutral Neutral Q6PID8 E295G Neutral Disease Q6PID8 D183G Neutral Disease Q14CZ0 N221S Neutral Neutral Q6IA86 T543P Neutral Disease Q6IA86 T128P Neutral Neutral Q6IA86 E795G Neutral Neutral Q6IA86 H806P Neutral Disease Q6IA86 V305M Neutral Neutral Q6IA86 I541T Neutral Neutral Q6IA86 T815P Neutral Neutral Q6IA86 H359R Neutral Disease Q14183 G48S Neutral Neutral Q9H2D6 G1019R Disease Neutral Q9NQG6 R169W Neutral Neutral Q9NQG6 D264N Neutral Neutral Q96C03 R354Q Neutral Neutral Q96C03 G324E Neutral Neutral Q9NQG6 T89M Neutral Neutral Q9NQG6 G78R Neutral Neutral P08236 L176F Disease Disease P08236 Y495C Disease Disease P08236 A354V Disease Disease P08236 G136R Disease Disease P08236 R374C Disease Disease P08236 L649P Neutral Neutral P08236 R577L Disease Disease P08236 P408S Disease Disease P08236 Y508C Disease Disease P08236 P415L Disease Neutral P08236 R611W Disease Disease P08236 Y626H Disease Disease P08236 E150K Disease Disease P08236 K606N Disease Disease P08236 R216W Disease Disease P08236 P148S Disease Neutral P08236 Y320C Disease Disease P08236 K350N Disease Disease P08236 S52F Disease Neutral P08236 G572D Disease Neutral P08236 R382H Disease Disease P08236 R477W Disease Disease P08236 Y320S Disease Neutral P08236 R382C Disease Disease P08236 A619V Disease Disease P08236 H351Y Disease Disease P08236 C38G Disease Neutral P08236 W627C Disease Disease P08236 R435P Disease Neutral O14842 R211H Neutral Disease O95045 R10S Neutral Neutral O95045 M78L Neutral Neutral Q8TDS4 R311C Neutral Disease P49019 R253H Neutral Neutral P49019 M317I Neutral Neutral Q9BXC0 H43Q Neutral Neutral P49019 M346I Neutral Neutral P49019 P173T Neutral Neutral P49019 L198F Neutral Neutral Q9BXC0 D253E Neutral Neutral Q8TDS4 M317I Neutral Neutral P49019 G350S Neutral Neutral Q6ZYL4 L21P Disease Disease Q499Z3 A30T Neutral Neutral Q499Z3 R144T Neutral Neutral Q499Z3 R128S Neutral Neutral Q99735 A101V Neutral Disease P82980 M115L Neutral Neutral P82980 E70Q Neutral Disease Q9UIQ6 S86P Neutral Neutral Q9UIQ6 I963V Neutral Neutral Q9UIQ6 A763T Neutral Neutral P50570 R369Q Disease Neutral P50570 S619W Disease Disease P50570 A618T Disease Disease P50570 R369W Disease Disease P50570 K562E Disease Disease P50570 E368K Disease Disease P50570 P263L Neutral Disease P50570 S619L Disease Disease P50570 R465W Disease Neutral Q5VWX1 G308A Neutral Disease Q9H3H9 G68A Neutral Neutral Q9H3H9 D19G Neutral Neutral Q969F9 R397W Disease Neutral Q33E94 N687S Neutral Neutral Q04826 E187L Neutral Disease P30447 L180W Neutral Disease Q30201 V53M Neutral Disease Q30201 R224G Disease Disease P30460 F91S Neutral Neutral P04439 G186A Neutral Disease Q04826 V17L Neutral Neutral P30487 I104T Neutral Neutral P10321 S101N Neutral Neutral P16188 Q86E Neutral Neutral P10321 T363A Neutral Neutral P30453 I3V Neutral Neutral Q29836 I90K Neutral Disease P16190 M358V Neutral Neutral P01891 V36M Neutral Disease P03989 Y83H Neutral Disease P30459 N90K Neutral Neutral Q29960 H153D Neutral Neutral P30495 S101N Neutral Neutral Q29865 V319A Neutral Neutral P16189 N90K Neutral Neutral Q9TNN7 F140S Neutral Disease P10321 S140F Neutral Disease P30483 S191W Neutral Neutral P30499 D138N Neutral Neutral P30460 Y140D Neutral Disease P30464 H137Y Neutral Neutral P30508 S101N Neutral Neutral P05534 G131W Neutral Disease P16188 W176R Neutral Neutral P01891 W180L Neutral Neutral P30457 D114A Neutral Neutral Q04826 S91F Neutral Disease Q29963 W180L Neutral Neutral Q29836 N87E Neutral Neutral P30460 V176E Neutral Neutral P30450 A100E Neutral Disease P30512 H126D Neutral Neutral P30495 T121R Neutral Neutral P30466 L180R Neutral Disease P01892 T187E Neutral Neutral P18464 L180D Neutral Disease P30505 T176E Neutral Neutral P30499 N92K Neutral Neutral P05534 L119V Neutral Disease P03989 N121S Neutral Neutral P30460 N138D Neutral Neutral Q30201 G93R Disease Disease P04222 Y140S Neutral Disease P10319 W171L Neutral Disease P01891 H175L Neutral Neutral P04439 E176V Neutral Neutral P04222 N104K Neutral Disease P30501 I10L Neutral Neutral P30459 R23W Neutral Disease P30487 K69T Neutral Neutral P30475 C91Y Neutral Neutral Q30201 A176V Disease Neutral P30450 I306V Neutral Neutral P30493 L140Y Neutral Neutral P30685 Y98D Neutral Disease P30484 D98G Neutral Neutral P30488 W191S Neutral Disease Q04826 W171L Neutral Disease P30493 T121R Neutral Neutral P30493 E176V Neutral Neutral P30461 L140S Neutral Neutral P30464 S91C Neutral Neutral P16188 S33Y Neutral Neutral P30475 M122T Neutral Disease P04222 I119L Neutral Neutral P03989 V176E Neutral Neutral P30491 V176E Neutral Neutral P10314 E185D Neutral Disease P01891 M121R Neutral Disease P13746 K168E Neutral Disease P30504 S35A Neutral Neutral Q07000 H137Y Neutral Neutral P10321 L171W Neutral Neutral P04222 D138V Neutral Neutral Q04826 H137Y Neutral Neutral P10314 R175H Neutral Disease P30501 N92K Neutral Neutral P30464 A48S Neutral Disease P30495 L140Y Neutral Neutral P30479 N104K Neutral Disease P30447 Y31C Neutral Disease P18465 V121R Neutral Neutral P30504 V52L Neutral Disease P01892 Y123C Neutral Disease P30493 T187E Neutral Neutral P10314 Q138R Neutral Neutral P18465 H137Y Neutral Neutral P30481 D85E Neutral Neutral P30483 Q139R Neutral Disease P05534 F123Y Neutral Neutral P18465 D138N Neutral Neutral P30453 P129S Neutral Neutral P30443 A100E Neutral Disease P30495 W119L Neutral Neutral P13747 G104R Neutral Disease P13747 R128G Neutral Neutral P13746 E43K Neutral Disease Q95365 N101S Neutral Neutral P10319 V176A Neutral Neutral P13746 F133L Neutral Neutral P30481 L187T Neutral Neutral P30457 R187E Neutral Neutral P18463 T104N Neutral Neutral Q07000 N90K Neutral Neutral P30453 K90N Neutral Neutral P30685 L127V Neutral Neutral P30450 D140N Neutral Disease Q30201 Q283P Disease Disease P30479 V127L Neutral Disease P30685 G107D Neutral Disease P10321 L119F Neutral Disease P03989 A235G Neutral Neutral Q9TNN7 K201E Neutral Neutral P01892 A260E Neutral Disease P30459 Q86G Neutral Neutral Q04826 N138D Neutral Neutral P30508 K90N Neutral Neutral P01892 T97I Neutral Neutral P16188 R80G Neutral Neutral P01891 R138H Neutral Neutral Q30201 R66C Disease Neutral P30495 L127V Neutral Neutral P05534 G89R Neutral Neutral P30457 S28W Neutral Disease P30499 Y140F Neutral Neutral Q04826 Y140N Neutral Disease P30464 P274L Neutral Disease P30685 G40V Neutral Disease P30504 W38R Neutral Neutral P30475 R121S Neutral Neutral P01892 V119L Neutral Neutral P30490 E176V Neutral Neutral P30462 L180R Neutral Disease Q30201 R330M Disease Disease P30450 R187L Neutral Disease P30450 W180Q Neutral Neutral P04439 G199R Neutral Disease P03989 S155R Neutral Neutral P01891 W180Q Neutral Neutral Q07000 G40S Neutral Disease Q9TNN7 N138D Neutral Neutral Q04826 L180R Neutral Disease P05534 H27Q Neutral Disease Q95365 I104T Neutral Neutral P30475 Y33D Neutral Disease P16188 Q94H Neutral Neutral Q29718 D186G Neutral Neutral P01892 L180Q Neutral Neutral P01892 L180W Neutral Disease Q04826 S121T Neutral Neutral Q29963 D33Y Neutral Neutral P05534 Q180L Neutral Neutral P30504 M327V Neutral Disease P30453 R121I Neutral Neutral P30460 L119W Neutral Disease P30493 S155R Neutral Neutral P01889 V306I Neutral Neutral P30493 L127V Neutral Neutral P05534 A5G Neutral Neutral P30685 L133F Neutral Disease P30460 D180R Neutral Neutral P05534 T206A Neutral Neutral Q29960 N104K Neutral Disease P30495 N138D Neutral Neutral P01889 R180D Neutral Disease P30492 Y33H Neutral Disease P04222 V127L Neutral Disease P30443 D114A Neutral Neutral P01892 A173T Neutral Neutral P30464 R121T Neutral Disease P13746 A176E Neutral Neutral P30466 R121N Neutral Disease P30495 Y195H Neutral Disease Q95604 L10I Neutral Disease P30491 N101S Neutral Neutral P30453 Q138R Neutral Neutral Q95365 N87E Neutral Neutral P30508 A97T Neutral Neutral P01891 Q94H Neutral Neutral P01892 H94Q Neutral Neutral Q04826 V176E Neutral Neutral P01892 W191G Neutral Disease P30466 S91F Neutral Disease P01892 V176E Neutral Neutral P18464 S155R Neutral Neutral P30491 I118T Neutral Neutral P30464 L119W Neutral Disease P30495 V176E Neutral Neutral P05534 M121R Neutral Disease P30508 N104K Neutral Disease P01889 D138N Neutral Neutral P01892 Y123F Neutral Disease P30499 E5A Neutral Neutral P30505 G199R Neutral Disease P30461 T121R Neutral Neutral P30486 S121R Neutral Neutral P16189 A114D Neutral Disease Q95365 C91S Neutral Neutral P18463 Y195H Neutral Disease P30499 S202T Neutral Neutral Q29836 I76V Neutral Neutral P30487 L56Q Neutral Neutral P30487 T65A Neutral Neutral P30498 F91C Neutral Neutral P30447 K151N Neutral Neutral Q30201 E277K Neutral Disease P03989 D101S Neutral Neutral Q30201 T217I Neutral Neutral P30479 N138D Neutral Neutral P30493 S101N Neutral Neutral Q29836 T97A Neutral Neutral P30485 D101S Neutral Neutral P30460 S121R Neutral Neutral Q04826 V127L Neutral Disease P30493 W119L Neutral Neutral P10321 L180D Neutral Disease P30499 M272V Neutral Neutral P30443 F33S Neutral Neutral P30501 E5A Neutral Neutral P30481 D180R Neutral Neutral P03989 D101N Neutral Neutral P30443 I121M Neutral Disease P30508 W180R Neutral Neutral P10314 M121I Neutral Disease P30685 R121S Neutral Disease P30461 E187L Neutral Disease P16189 M121I Neutral Disease P10321 A348V Neutral Disease P30460 S101N Neutral Neutral P10321 M331K Neutral Disease P10321 N104K Neutral Disease P30493 E82A Neutral Disease P01891 D140H Neutral Disease P10321 E201K Neutral Disease P30504 G40S Neutral Disease P01891 T97I Neutral Neutral P30459 G103A Neutral Neutral Q29960 Q180W Neutral Neutral P30499 E179Q Neutral Neutral P30508 G144V Neutral Disease P16190 R41S Neutral Disease P30488 L127V Neutral Neutral Q29836 E69G Neutral Neutral P30464 S91Y Neutral Neutral P10319 R121W Neutral Disease P30455 V182A Neutral Neutral P30475 S35A Neutral Neutral P30475 C91S Neutral Neutral P30685 L180R Neutral Disease P30505 L180R Neutral Disease P30461 Y183C Neutral Disease Q30201 H63D Disease Disease P01892 R121M Neutral Disease P01892 W131G Neutral Neutral Q04826 Y140S Neutral Disease P30459 T97A Neutral Neutral Q07000 H45R Neutral Neutral Q30201 V295A Disease Neutral Q95365 Y98D Neutral Disease P30460 N87D Neutral Neutral P30479 W119L Neutral Neutral P30461 L169R Neutral Neutral Q04826 S121R Neutral Neutral P30510 R45H Neutral Disease P30493 T187L Neutral Neutral Q95365 E69T Neutral Neutral P30475 L180R Neutral Disease Q30201 V59M Neutral Disease P16189 Q138R Neutral Neutral P30498 D98Y Neutral Neutral Q04826 L9V Neutral Disease P01892 F33Y Neutral Neutral P10314 P129S Neutral Neutral P01892 M162K Neutral Disease P30501 K202T Neutral Neutral Q30201 R6S Disease Neutral P10314 L180Q Neutral Neutral P03989 H138D Neutral Neutral P30443 R41S Neutral Disease P01892 Q67R Neutral Neutral P01892 E190D Neutral Disease P30491 Y195H Neutral Disease P30450 N90K Neutral Neutral P30491 L127V Neutral Neutral Q30201 S65C Disease Neutral Q95365 T187M Neutral Neutral Q29836 E100V Neutral Neutral P30475 L119W Neutral Disease P30479 R121S Neutral Disease P30505 T162K Neutral Disease P04222 G115R Neutral Disease P30504 S33Y Neutral Neutral P04222 I118T Neutral Neutral Q95365 C91F Neutral Neutral P30481 N101S Neutral Neutral Q07000 T97A Neutral Neutral P30481 D140Y Neutral Neutral P01891 S129P Neutral Disease P30685 D138N Neutral Neutral P30493 L180R Neutral Disease P01891 D98H Neutral Disease P30510 S101N Neutral Neutral P30453 W180L Neutral Neutral Q95604 A24T Neutral Disease P30475 V36M Neutral Disease Q95365 E82G Neutral Disease P30508 R121W Neutral Disease P30475 Y123S Neutral Disease P30504 E73A Neutral Neutral P01891 R138E Neutral Neutral P10314 Q168K Neutral Neutral Q30201 C282Y Disease Disease P04222 S101N Neutral Neutral P30499 Y140S Neutral Disease Q04826 L119W Neutral Disease P30462 S35A Neutral Neutral P30453 L312I Neutral Neutral P30490 H195Y Neutral Neutral P05534 T187R Neutral Neutral P03989 D140Y Neutral Disease Q9TNN7 V218I Neutral Neutral Q07000 L140S Neutral Neutral P18462 Y33F Neutral Disease P30466 N87E Neutral Neutral P13746 R187T Neutral Neutral P10319 L187T Neutral Neutral P30685 T69E Neutral Neutral P16188 T55A Neutral Neutral P30466 T187E Neutral Neutral P30475 N87E Neutral Neutral P18462 H94Q Neutral Neutral P04439 L180Q Neutral Neutral P30460 D180L Neutral Neutral P30685 S140Y Neutral Neutral P30685 S140F Neutral Disease P30508 S101G Neutral Neutral P30475 R121T Neutral Disease P30495 L180W Neutral Disease Q29960 S101N Neutral Neutral P30475 N138D Neutral Neutral P30495 E69T Neutral Neutral P30475 F140S Neutral Disease P05534 Q180W Neutral Neutral P30450 E176V Neutral Neutral P01891 D140Y Neutral Disease P30491 N101D Neutral Neutral P30481 D180L Neutral Neutral P18464 E176V Neutral Neutral P01892 K90N Neutral Neutral P30685 F91S Neutral Neutral P30487 T48A Neutral Neutral P30512 N90H Neutral Neutral P30480 Y33H Neutral Disease P18465 L180R Neutral Disease P18464 H195Y Neutral Neutral P03989 T104N Neutral Neutral P30499 R180W Neutral Disease P30510 T97A Neutral Neutral P10314 L133F Neutral Disease P30504 R180L Neutral Neutral P18464 W191G Neutral Disease P30475 Q168R Neutral Neutral P30685 N87E Neutral Neutral P01891 D140V Neutral Disease Q29960 C157W Neutral Neutral P30685 A48S Neutral Disease P18465 S140Y Neutral Neutral P13746 T345S Neutral Neutral P30475 D98Y Neutral Neutral P18465 V127L Neutral Disease Q95365 S35A Neutral Neutral P01892 D54N Neutral Disease Q04826 Q204E Neutral Disease P10314 V176E Neutral Neutral P30501 S364C Neutral Neutral Q30201 I105T Disease Neutral P01889 S121R Neutral Neutral P04222 K90N Neutral Neutral P13747 R178G Neutral Disease P04222 R121S Neutral Disease P16190 H195Y Neutral Neutral P10321 S123Y Neutral Neutral P03989 D140H Neutral Disease P30481 E87N Neutral Disease P30443 G80R Neutral Disease P30481 T65A Neutral Neutral P30501 E179Q Neutral Neutral P10321 T187L Neutral Neutral P04439 D185E Neutral Neutral P30491 S140F Neutral Disease P05534 E86G Neutral Neutral Q30201 Q127H Disease Disease Q04826 E87N Neutral Disease P30493 T121S Neutral Neutral P30511 S272P Neutral Disease P30495 L140S Neutral Neutral P30491 Y123S Neutral Disease P01892 H98D Neutral Neutral Q9TNN7 A223V Neutral Neutral Q04826 T167S Neutral Neutral P30461 N138D Neutral Neutral P10319 G86E Neutral Neutral P30464 W180L Neutral Neutral P30460 S121T Neutral Neutral Q29836 A93R Neutral Neutral P30455 E185D Neutral Disease P01889 E187L Neutral Neutral P16188 H21Q Neutral Neutral P30464 E87N Neutral Disease P30466 H195Y Neutral Neutral P30443 V182A Neutral Neutral P10314 S101N Neutral Neutral P30450 F60L Neutral Neutral P16188 L180W Neutral Disease P30443 R180L Neutral Neutral P30485 T104N Neutral Neutral P13746 H175R Neutral Neutral P30466 Y98D Neutral Disease P30443 M91V Neutral Neutral P30499 V328M Neutral Disease P30504 R45H Neutral Disease P01892 A65G Neutral Neutral P30499 W243R Neutral Neutral Q07000 L140F Neutral Neutral Q30201 G43D Disease Disease P30499 S364C Neutral Neutral P10321 K90N Neutral Neutral Q8TEM1 I608V Neutral Neutral Q8TEM1 A944P Neutral Disease Q8TEM1 A755V Neutral Neutral Q8TEM1 M1096I Neutral Neutral Q8TEM1 D1430E Neutral Neutral Q8TEM1 A297T Neutral Neutral Q8TEM1 L1752S Neutral Neutral Q8TEM1 V1787M Neutral Neutral Q8TEM1 P821A Neutral Neutral Q8TEM1 R786L Neutral Neutral Q5BVD1 S144G Neutral Neutral Q5BVD1 I111V Neutral Neutral P12524 S362T Neutral Neutral Q5JTC6 K292N Disease Neutral P00387 L149P Disease Disease P00387 T117S Neutral Neutral P00387 G292D Disease Disease P00387 R58Q Disease Neutral Q6BCY4 N209D Neutral Neutral P00387 L73P Disease Disease P00387 C204Y Disease Disease P00387 A179V Disease Disease P00387 S66P Neutral Disease Q6BCY4 E15A Neutral Neutral P00387 V106M Disease Disease P00387 C204R Disease Disease P00387 S128P Disease Disease Q8WUX2 R82G Neutral Disease Q8NBV4 T174M Neutral Neutral Q8NBV4 L267V Neutral Neutral Q8IYT1 G319D Neutral Neutral Q8TC56 V599I Neutral Neutral Q8IYT1 N551D Neutral Neutral Q8IYT1 N253S Neutral Neutral Q8IYT1 T577M Neutral Neutral Q8TC56 M564T Neutral Neutral Q8TC56 A543V Neutral Neutral Q8IYT1 N22D Neutral Neutral P39905 D150N Disease Neutral P39905 P21S Disease Neutral P39905 R93W Disease Neutral P39905 T154S Disease Neutral P39905 I211M Disease Neutral Q86W34 D30N Neutral Neutral Q9UQV4 E32G Neutral Neutral Q9UQV4 I318V Neutral Neutral P00736 E184K Neutral Neutral P00736 S152L Neutral Neutral O00187 Y371D Neutral Disease P09871 V327L Neutral Neutral O00187 R439H Neutral Disease P00736 Y131H Neutral Neutral O00187 H155R Neutral Neutral P00736 H163Y Neutral Disease P09871 R383H Neutral Neutral O00187 V377A Neutral Neutral P09871 R119H Neutral Disease P00736 G261R Neutral Disease Q13243 A160S Neutral Disease Q08AI8 L309P Neutral Neutral P43034 H277P Disease Neutral P43034 H149R Disease Disease P43034 S169P Disease Disease P43034 G162S Disease Neutral P43034 D317H Disease Disease P43034 R241P Disease Neutral P43034 F31S Disease Disease Q8N468 G314A Neutral Neutral Q8N468 L228I Neutral Neutral P41968 V81I Neutral Neutral P41968 T6K Neutral Neutral Q9P0P0 Y118H Neutral Neutral P21964 A102T Neutral Neutral P21964 V158M Neutral Neutral P21964 A72S Neutral Neutral P21964 C34S Neutral Neutral P21964 A146V Neutral Disease Q7L7X3 A855T Neutral Neutral A2VDJ0 N1254S Neutral Neutral A2VDJ0 I604V Neutral Neutral A2VDJ0 S1110Y Neutral Neutral A2VDJ0 A1392P Neutral Neutral A2VDJ0 M645T Neutral Neutral P01037 P31L Neutral Neutral P01037 R131M Neutral Neutral P01034 L94Q Disease Disease P01037 H4Y Neutral Neutral P01037 K135N Neutral Neutral P01037 N129D Neutral Neutral P28325 C46R Neutral Neutral P01034 A25T Neutral Neutral Q7Z6I6 L591V Neutral Neutral Q7Z6I6 F70L Neutral Neutral O43683 G20D Neutral Disease O43683 E36D Disease Neutral O43683 N534D Neutral Neutral O43683 Y259C Disease Neutral O43683 S492Y Disease Neutral O43683 P648R Disease Neutral O43683 H265N Disease Neutral O00217 R102H Disease Disease O00217 P79L Disease Disease P51826 S358N Neutral Neutral P51826 N494S Neutral Neutral O43908 S29I Neutral Neutral O43908 S104N Neutral Neutral P32942 S525T Neutral Neutral P05362 P352L Neutral Neutral P05362 V315M Neutral Neutral P05362 R397Q Neutral Neutral P05362 K155N Neutral Disease P05362 K469E Neutral Neutral P05362 K56M Neutral Neutral P05362 R478W Neutral Neutral P05362 G241R Neutral Neutral Q6ICG8 Q285H Neutral Neutral Q6ICG8 C170F Neutral Neutral Q6ICG8 Q5E Neutral Neutral Q6ICG8 D121G Neutral Neutral Q5XG99 A180G Neutral Neutral Q5XG99 A157V Neutral Neutral Q5XG99 A161V Neutral Neutral P14416 P310S Neutral Neutral P14416 V154I Disease Neutral P14416 S311C Neutral Disease Q9H2N8 R121C Neutral Neutral Q86UD4 N182D Neutral Neutral Q12950 G136D Neutral Neutral Q12950 I134F Neutral Disease Q12950 I152V Neutral Neutral P57679 S307P Disease Neutral P57679 R443Q Disease Neutral P57679 G403S Neutral Neutral P57679 Q74P Neutral Neutral P57679 T449K Neutral Neutral P57679 R576Q Neutral Neutral P57679 R760Q Neutral Neutral P57679 D953G Neutral Neutral P57679 T372M Neutral Neutral P57679 Y258H Neutral Neutral P57679 A114V Neutral Neutral P01266 Q2170R Neutral Neutral P01266 P2149L Neutral Neutral P01266 Q830E Neutral Neutral P01266 A1936T Neutral Neutral P01266 M1028V Neutral Neutral P01266 C1264R Disease Neutral P01266 Q515E Neutral Neutral P01266 S734A Neutral Neutral P01266 P1463H Neutral Neutral P01266 H1043Y Neutral Disease P01266 R1979W Neutral Neutral P01266 C1996S Disease Disease P01266 Q135H Neutral Neutral P01266 D1312G Neutral Neutral P01266 I1059T Neutral Neutral P01266 R2242H Neutral Disease P01266 W1437R Neutral Neutral P01266 R2530Q Neutral Neutral P01266 G653D Neutral Neutral P01266 D2091E Neutral Neutral P01266 Q870H Disease Neutral P01266 R1999W Neutral Neutral P01266 D1838N Neutral Neutral P01266 W2501R Neutral Disease O76090 G135S Disease Neutral O76090 A10V Disease Disease O76090 D303E Disease Disease O76090 L100R Disease Disease O76090 V235M Disease Disease O76090 E306D Disease Disease O76090 E525A Neutral Neutral O76090 T307A Disease Disease O76090 A243T Disease Disease O76090 S209N Disease Neutral O76090 A10T Disease Disease O76090 V9A Disease Disease O76090 T307I Disease Disease O76090 L207I Disease Neutral O76090 I73N Disease Disease O76090 D301E Disease Disease O76090 Q58L Disease Disease O76090 I201T Disease Disease O76090 F17C Disease Disease O76090 L82V Disease Disease O76090 F305S Disease Disease O76090 E300D Disease Disease O76090 E306G Disease Disease O76090 P297S Disease Disease O76090 E578V Neutral Neutral O76090 W102R Disease Disease O76090 P101T Disease Disease O76090 R141H Disease Disease O76090 T241N Disease Disease O76090 N11I Disease Disease O76090 N308S Disease Disease O76090 S16F Disease Neutral O76090 I295T Disease Disease O76090 F80L Disease Disease O76090 F298S Disease Disease O76090 D302H Disease Disease O76090 N133K Disease Neutral O76090 R218C Disease Disease O76090 E300K Disease Disease O76090 R92C Disease Disease O76090 V89A Disease Disease O76090 R47H Disease Neutral O76090 S27R Disease Disease O76090 L41P Disease Disease O76090 T6R Disease Disease O76090 V311G Disease Disease O76090 L224P Disease Disease O76090 T6P Disease Disease O76090 D104H Disease Disease O76090 A146K Disease Disease O76090 I310T Disease Disease O76090 G26R Disease Disease O76090 L294V Disease Disease O76090 R92S Disease Disease O76090 L21V Disease Disease O76090 R218S Disease Disease O76090 L67V Neutral Neutral O76090 N296S Disease Disease O76090 R25Q Disease Disease O76090 R25W Disease Disease O76090 V235L Disease Disease O76090 Y85H Disease Disease O76090 L140R Disease Disease O76090 Y227N Disease Disease O76090 F276L Disease Disease O76090 L567F Neutral Neutral O76090 K30R Disease Disease O76090 N296H Disease Disease O76090 P297A Disease Disease O76090 F113L Disease Neutral O76090 E119Q Disease Disease O76090 W93C Disease Disease O76090 E557K Neutral Neutral O76090 Q293K Disease Disease O76090 T561A Neutral Neutral O76090 V9M Disease Disease O76090 R13H Disease Neutral O76090 T91I Disease Neutral O76090 W24C Disease Disease O76090 Q96H Disease Disease O76090 R218Q Disease Disease O76090 G299E Disease Disease O76090 D302G Disease Disease O76090 N99K Disease Disease O76090 S231R Disease Disease O76090 R218H Disease Disease O76090 D104E Disease Disease O76090 L224M Disease Disease O76090 Y29H Disease Disease O76090 T237R Disease Disease O76090 D301N Disease Disease O76090 D302V Disease Disease O76090 D312N Disease Disease O76090 A195V Disease Disease O76090 Y227C Disease Disease O76090 C221W Disease Disease O76090 A243V Disease Disease O76090 R92H Disease Disease P59942 E42K Neutral Neutral P59942 T53M Neutral Neutral P59942 N45S Neutral Neutral P10636 K634M Disease Disease P10636 V654M Disease Disease P10636 R5L Disease Neutral P10636 E659V Disease Neutral P10636 P618L Disease Disease P10636 N596K Disease Disease P10636 N613H Disease Disease P10636 G620V Disease Disease P10636 S447P Neutral Neutral P10636 H441Y Neutral Neutral P10636 S622N Disease Neutral P10636 G589V Disease Disease P10636 R5H Disease Neutral P10636 L583V Disease Neutral P10636 P618S Disease Disease P13612 R884Q Neutral Neutral A5D8V6 V182D Neutral Neutral A5D8V6 S198L Neutral Neutral A5D8V6 S261A Neutral Neutral Q8IVY1 S12L Neutral Neutral Q8IY42 A151T Neutral Neutral Q8IY42 E274G Neutral Neutral A4QMU0 I84T Neutral Neutral Q5JRV8 P345Q Neutral Neutral Q8N123 Y3S Neutral Neutral Q8N123 R131H Neutral Neutral P32320 K27Q Neutral Neutral P33032 F209L Neutral Disease P01133 D981E Neutral Neutral P01133 M842T Neutral Neutral P01133 H151Y Neutral Neutral P01133 L1043F Neutral Neutral P01133 S16R Neutral Disease P01133 I708M Neutral Neutral P01133 V920E Neutral Neutral P01133 D257H Neutral Disease P01133 L292H Neutral Disease P01133 A1084G Neutral Neutral P01133 D784V Neutral Disease P01133 G723R Neutral Neutral P01133 R431K Neutral Neutral P01133 S638R Neutral Disease P01133 P1070L Disease Neutral Q8NF50 R1008W Neutral Disease Q8NF50 E237K Neutral Neutral Q8NF50 A1970P Neutral Disease Q8NF50 A597V Neutral Disease Q8NF50 N413S Neutral Neutral Q8NF50 P97T Neutral Neutral P51504 D253A Neutral Neutral Q15072 R8K Neutral Neutral Q15070 V91I Neutral Neutral Q15070 V44A Neutral Neutral O95237 S175R Disease Disease Q8IYM2 S43R Neutral Neutral Q8IYM2 C168R Neutral Neutral P46379 S625P Neutral Neutral P46379 A728V Neutral Neutral Q9UBD5 Q94K Neutral Neutral Q9UBD5 T389P Neutral Disease Q9UBD5 R588C Neutral Neutral Q9UBD5 I247V Neutral Neutral Q9UBD5 Q126R Neutral Neutral Q9UBD5 A626T Neutral Neutral Q9UBD5 V217I Neutral Neutral Q9UBD5 T287M Neutral Neutral Q9P2J2 S1026T Neutral Neutral Q9P2J2 P1117T Neutral Neutral Q9P2J2 R474P Neutral Disease Q9P2J2 P914L Neutral Neutral Q9P2J2 G34E Neutral Disease P28340 R119H Neutral Neutral P28340 R177H Neutral Neutral P28340 R19H Neutral Neutral P28340 R1086Q Neutral Neutral P28340 R849H Neutral Neutral P28340 S173N Neutral Neutral P28340 R30W Neutral Neutral Q9Y3T9 A271V Neutral Neutral Q9Y3T9 V300I Neutral Neutral P16109 S385L Neutral Disease P16109 C230F Neutral Disease P16109 M365V Neutral Disease P16109 L640V Neutral Neutral P16109 V209M Neutral Neutral P16109 E542K Neutral Neutral P16109 I274T Neutral Neutral P16109 G631V Neutral Neutral P16109 N603D Neutral Neutral P16109 T661N Neutral Neutral P16109 G179R Neutral Disease P16109 S331N Neutral Neutral P16109 S619A Neutral Disease P16109 T756P Neutral Neutral P16109 S500F Neutral Neutral P16109 N673S Neutral Neutral P16109 P301L Neutral Neutral Q9BUB4 T203N Neutral Neutral Q9BUB4 H167N Neutral Neutral Q8IYS5 S97I Neutral Neutral Q6P2Q9 Y2334N Disease Neutral Q6P2Q9 F2314L Disease Disease Q6P2Q9 R227H Neutral Neutral Q6P2Q9 R2310K Disease Disease Q6P2Q9 K68E Neutral Disease Q6P2Q9 P874L Neutral Disease Q6P2Q9 H2309R Disease Disease Q6P2Q9 H2309P Disease Disease Q6P2Q9 N1293H Neutral Neutral Q6P2Q9 F2304L Disease Disease Q6P2Q9 P2301T Disease Disease Q6P2Q9 R2310G Disease Disease Q8NBP7 H417Q Neutral Neutral Q8NBP7 R46L Neutral Neutral Q8NBP7 S127R Disease Disease Q8NBP7 E670G Neutral Neutral Q8NBP7 H391N Neutral Disease Q8NBP7 E482G Neutral Neutral Q8NBP7 N425S Neutral Neutral Q8NBP7 I474V Neutral Neutral Q8NBP7 A443T Neutral Neutral Q8NBP7 A53V Neutral Neutral Q8NBP7 Q554E Neutral Neutral Q8NBP7 H553R Neutral Neutral Q8NBP7 R237W Neutral Neutral Q8NBP7 L253F Neutral Disease Q8NBP7 Q619P Neutral Neutral Q8NBP7 F216L Disease Disease Q8NBP7 E57K Neutral Neutral Q8NBP7 R469W Neutral Neutral Q8NBP7 F515L Neutral Disease Q9UKB5 G263R Neutral Neutral Q96M66 R171S Neutral Neutral Q96M66 R37H Neutral Neutral O00294 R67T Neutral Neutral O00294 A496T Disease Neutral O00294 F382S Disease Disease O00294 I459K Disease Disease O00294 N261T Disease Neutral O00294 N261K Neutral Neutral O00294 I259T Disease Neutral O00294 F491L Disease Disease O00294 K489R Disease Disease O00294 T454M Disease Neutral O00294 R420P Disease Disease O00294 A245V Disease Neutral O00294 R378H Disease Neutral P0C0L4 P726L Neutral Neutral P0C0L5 L1210R Neutral Disease P0C0L4 D1073G Neutral Disease P0C0L4 S347Y Neutral Neutral P0C0L5 S347Y Neutral Neutral P01024 R1320Q Disease Neutral P0C0L4 R477W Neutral Neutral P0C0L4 A907T Neutral Neutral P0C0L5 S1286A Neutral Neutral P0C0L5 V1207A Neutral Neutral P01024 H1601N Neutral Neutral P01024 P314L Neutral Neutral P01024 Q1521R Neutral Neutral P0C0L4 S1201T Neutral Neutral P01024 E469D Neutral Neutral P01024 R863K Neutral Neutral P0C0L5 N1176S Neutral Neutral P0C0L5 A907T Neutral Neutral P01024 I1367T Neutral Neutral P0C0L5 S1201T Neutral Neutral P01024 S1619R Neutral Disease P01024 D549N Disease Disease P01024 R102G Neutral Neutral P0C0L4 L1210R Neutral Disease P0C0L4 V1207A Neutral Neutral P0C0L4 N1176S Neutral Neutral P0C0L5 D1073G Neutral Disease P0C0L4 S1286A Neutral Neutral P01024 G1224D Neutral Disease P0C0L4 D727N Neutral Neutral Q16828 V114L Neutral Disease Q6ZSS7 R205G Neutral Neutral Q8N5R6 S480N Neutral Neutral P10253 H308P Disease Disease P10253 G607D Disease Disease P10253 R600H Disease Disease P10253 G219R Disease Neutral P10253 L405P Disease Disease P10253 G549R Disease Disease P10253 G309R Disease Disease P10253 P324L Disease Neutral P10253 W402R Disease Disease P10253 D645E Disease Disease P10253 Y575S Disease Disease P10253 G615R Disease Disease P10253 C647W Disease Disease P10253 S566P Disease Disease P10253 L552P Disease Disease P10253 P545L Disease Disease P10253 D91N Neutral Disease P10253 A880D Disease Disease P10253 R672W Disease Disease P10253 R224W Disease Disease P10253 M519V Disease Disease P10253 W746C Neutral Neutral P10253 G293R Disease Disease P10253 M318T Disease Disease P10253 V816I Neutral Neutral P10253 R600C Disease Disease P10253 V949D Disease Disease P10253 L312R Disease Disease P10253 H612Q Disease Disease P10253 W330G Disease Neutral P10253 L901Q Disease Disease P10253 G648S Disease Disease P10253 A445P Disease Neutral P10253 C374R Disease Disease P10253 P457L Disease Neutral P10253 E579K Disease Neutral P10253 G576A Neutral Neutral P10253 G377R Disease Disease P10253 M519T Disease Disease P10253 L208P Disease Disease P10253 A237V Disease Neutral P10253 Y455F Disease Disease P10253 C103G Disease Disease P10253 D645H Disease Disease P10253 L355P Disease Disease P10253 E521K Disease Disease P10253 R437C Disease Disease P10253 E262K Disease Disease P10253 R672Q Disease Disease P10253 D404N Disease Disease P10253 L299R Disease Disease P10253 D489N Disease Disease P10253 W481R Disease Disease P10253 H223R Neutral Neutral P10253 P361L Disease Disease P10253 G478R Disease Disease P10253 G643R Disease Disease P10253 P285R Disease Disease P10253 T927I Neutral Neutral P10253 R725W Disease Disease P10253 E689K Neutral Disease P10253 R199H Neutral Neutral P10253 D645N Disease Disease P10253 S529V Disease Neutral P10253 Y292C Disease Disease P10253 P768R Disease Disease P10253 I780V Neutral Neutral P10253 G576S Neutral Disease P10253 M408V Disease Neutral Q8NBL1 P229T Neutral Disease Q8NBL1 K75R Neutral Neutral Q6ZWB6 P329L Neutral Neutral Q6ZNB6 P246L Neutral Neutral Q2KHR3 N1304D Neutral Neutral Q2KHR3 S1018N Neutral Neutral Q2KHR3 Q644R Neutral Neutral P58004 T320A Neutral Neutral Q9Y6P5 L44I Neutral Neutral Q6ZRF7 E14K Neutral Neutral Q8IV45 R432G Neutral Neutral Q6NW34 E101K Neutral Neutral Q6NW34 T476A Neutral Neutral Q6NW34 S490P Neutral Neutral Q6NW34 P352S Neutral Neutral Q6NW34 F357I Neutral Neutral Q5T3F8 V307M Neutral Neutral Q9P1W3 M654V Neutral Neutral O94886 V622M Neutral Neutral Q9BXW9 R328Q Neutral Neutral Q9BXW9 R1236H Disease Disease Q9BXW9 Q65H Neutral Neutral Q9BXW9 S126G Disease Neutral Q9BXW9 Q623P Neutral Neutral Q9BXW9 R302W Disease Disease Q9BXW9 K865R Neutral Neutral Q9BXW9 K33R Neutral Neutral Q9BXW9 L456R Neutral Disease Q9BXW9 L446V Neutral Neutral Q9BXW9 G901V Neutral Neutral Q9BXW9 T61M Neutral Neutral Q9BXW9 T193A Neutral Neutral Q9BXW9 I172M Neutral Neutral Q9BXW9 P714L Neutral Neutral Q8IYW4 I109T Neutral Disease Q53GL7 V630A Neutral Neutral Q53GL7 I249V Neutral Neutral Q53GL7 L395P Neutral Neutral P12645 R192Q Neutral Neutral P16083 K16R Neutral Neutral P16083 G58D Neutral Disease P16083 V184A Neutral Disease P16083 F47L Neutral Disease P16083 E29G Neutral Neutral Q96MG2 R233Q Neutral Neutral Q96MG2 V92A Neutral Neutral Q15738 G205S Disease Disease Q15738 A105V Disease Disease Q5T6J7 K185T Neutral Neutral Q96T76 G790D Neutral Neutral Q96T76 R983H Neutral Neutral Q96T76 M365V Neutral Neutral Q96T76 Q409P Neutral Neutral Q96T76 A558V Neutral Neutral Q96T76 V526I Neutral Neutral Q96T76 R98W Neutral Disease Q96T76 Q434E Neutral Neutral Q96T76 V197I Neutral Neutral Q96T76 R306H Neutral Disease Q96T76 A68G Neutral Neutral P58872 V255M Neutral Neutral Q9UPM8 C163R Neutral Disease Q6PEX7 A253V Neutral Neutral Q6PEX7 E158D Neutral Neutral Q8N139 V282I Neutral Neutral O94911 T256A Neutral Neutral Q8WWZ4 P203S Neutral Neutral Q8WWZ4 V287I Neutral Neutral Q8N139 M698I Neutral Neutral O94911 Y489F Neutral Neutral Q8WWZ7 M960V Neutral Neutral Q8IUA7 N785S Neutral Disease O94911 C680G Neutral Neutral Q8WWZ4 T916M Neutral Neutral Q8IUA7 G1356S Neutral Disease O94911 G331S Neutral Disease Q8WWZ7 A832S Neutral Neutral Q8WWZ7 Q93K Neutral Neutral Q8N139 N1322S Neutral Disease Q8N139 M875I Neutral Neutral Q8IUA7 K1306T Neutral Neutral Q8WWZ7 Q484R Neutral Neutral Q8IUA7 R353H Neutral Disease Q8WWZ7 M753V Neutral Neutral Q8N139 N610Y Neutral Neutral Q8N2C7 R131W Neutral Neutral P14778 A124G Neutral Neutral P14778 T344M Neutral Neutral Q9HB29 V352I Neutral Neutral Q9HB29 L550P Neutral Disease Q96AA3 A185T Neutral Neutral Q5VWG9 R927S Neutral Neutral Q5VWG9 V598L Neutral Neutral P02647 K131M Neutral Neutral P02647 T92I Neutral Neutral P02647 E163G Neutral Neutral P02647 P189R Neutral Disease P02647 E171V Neutral Disease P02647 D113E Neutral Neutral P02647 P27R Neutral Disease P02647 A61T Neutral Neutral P02647 D126H Neutral Neutral P02647 L84R Disease Disease P02647 R184P Neutral Disease Q14331 K66E Neutral Neutral Q08397 R141L Neutral Neutral Q08397 G153D Neutral Neutral Q6ZSY5 F287S Neutral Neutral P20809 R112H Neutral Neutral P20809 V108M Neutral Neutral Q6ZR08 G894S Neutral Disease Q6ZR08 Y741F Neutral Neutral Q9Y2G4 V128I Neutral Neutral Q9Y2G4 T545A Neutral Neutral Q9Y2G4 T233M Neutral Neutral Q9Y2G4 Q122E Neutral Neutral P37840 A53T Disease Neutral P37840 A30P Disease Disease P37840 E46K Disease Neutral P04180 M317I Disease Disease P04180 A117T Disease Disease P04180 P331S Disease Disease P04180 S115P Neutral Disease P04180 R182C Neutral Neutral P04180 T345M Disease Disease P04180 R164C Disease Disease P04180 R123C Disease Disease P04180 F406V Disease Neutral P04180 V70E Disease Disease P04180 V333M Disease Disease P04180 R164H Disease Disease P04180 Y180N Disease Disease P04180 G54S Disease Disease P04180 A165T Neutral Disease P04180 T298A Disease Disease P04180 R268H Disease Disease P04180 R171W Disease Disease P04180 S205N Disease Disease P04180 T298I Disease Disease P04180 K242N Disease Disease P04180 R159Q Disease Disease P04180 S232T Neutral Neutral P04180 N29I Disease Disease P04180 G57R Disease Disease P04180 T147I Disease Neutral P04180 T37M Disease Neutral P04180 R159W Disease Disease P04180 L233P Disease Disease P04180 P34L Disease Neutral P04180 T371M Disease Disease P04180 N252K Disease Disease P04180 M276K Disease Disease P04180 P34Q Disease Neutral A6NGE4 R549W Neutral Neutral Q01718 R128C Disease Disease Q01718 R137W Disease Disease Q01718 R146H Disease Disease Q01718 D103N Disease Disease Q01718 D107N Disease Disease Q01718 S74I Disease Disease Q01718 Y254C Disease Disease Q01718 S120R Disease Disease Q01718 P27R Neutral Disease Q01718 C251F Disease Disease O75503 D279N Disease Neutral O75503 K368R Neutral Neutral Q9NWM3 P205S Neutral Neutral Q9NWM3 R316Q Neutral Neutral P11465 V20L Neutral Neutral P31997 R114K Neutral Disease Q15238 K154N Neutral Neutral P40199 V239G Neutral Neutral Q14676 S586A Neutral Neutral Q14676 E371K Neutral Neutral Q14676 E251K Neutral Neutral Q14676 S1540P Neutral Disease Q14676 E1509D Neutral Neutral Q14676 R268K Neutral Neutral P04406 A22G Neutral Neutral Q15788 P794A Neutral Neutral Q15788 V1238I Neutral Neutral Q15788 P1272S Neutral Neutral Q15788 I591T Neutral Neutral Q15788 E685A Neutral Neutral Q15788 M1154T Neutral Neutral Q15788 S474P Neutral Neutral Q15788 S999F Neutral Neutral Q15788 N466K Neutral Neutral Q15788 Q457K Neutral Neutral Q969X1 P21L Neutral Neutral O15379 N411S Neutral Neutral Q9Y388 R287H Neutral Neutral Q14315 R1567Q Neutral Neutral O75369 L234V Disease Neutral O75369 G1834R Disease Disease P21333 S1199L Disease Disease Q14315 P2203R Neutral Neutral P21333 L172F Disease Disease P21333 R196W Disease Disease O75369 L1431R Disease Disease P21333 A1188T Disease Disease P21333 V528M Disease Neutral O75369 P1603L Disease Disease O75369 V1592D Disease Disease P21333 A200S Disease Disease P21333 E254K Disease Disease P21333 A128V Disease Disease P21333 A273P Disease Disease Q14315 S2626N Neutral Neutral P21333 T555K Disease Disease P21333 V320A Neutral Neutral P21333 V552A Neutral Disease P21333 D1159A Disease Disease O75369 A173V Disease Disease P21333 S1186L Disease Disease P21333 Q170P Disease Disease P21333 A1764T Disease Neutral P21333 L656F Disease Neutral Q14315 A1599T Neutral Neutral Q14315 G1580D Neutral Neutral O75369 G751R Disease Disease O75369 L171R Disease Disease O75369 M1471V Neutral Neutral P21333 E82V Disease Disease O75369 F161C Disease Disease P21333 P207L Disease Disease O75369 G363E Disease Disease O75369 G1586R Disease Disease P21333 R196G Disease Disease O75369 G361S Disease Disease O75369 N1157D Neutral Neutral O75369 E1179K Neutral Disease O75369 M202V Disease Disease O75369 G1691S Disease Disease P21333 A1419G Neutral Neutral O75369 V1018M Neutral Disease P21333 C1645F Disease Disease O75369 S235P Disease Disease P21333 D1184E Disease Disease Q14315 K2135R Neutral Neutral P21333 S149F Disease Disease O75369 E227K Disease Disease Q14315 K2637Q Neutral Disease O75369 S188P Disease Disease P21333 S1012L Neutral Disease P21333 A39G Disease Disease P21333 M102V Disease Disease P21333 D203Y Disease Disease P21333 F370L Neutral Disease P21333 G1728C Disease Disease O75369 G168S Disease Disease Q9UEW3 F282S Neutral Neutral Q13316 S69C Neutral Neutral Q13316 D117N Disease Neutral Q13316 K463R Neutral Neutral Q13316 R272H Neutral Neutral P12018 S122L Neutral Neutral P12018 E132K Neutral Neutral P12018 D76N Neutral Neutral Q96GW7 E504K Neutral Neutral Q86UW7 A298T Neutral Neutral Q9UHN1 G416A Neutral Neutral Q9UHN1 A169T Neutral Neutral Q9UHN1 G451E Disease Neutral Q8N3Y3 R546W Neutral Neutral Q8N3Y3 R677C Neutral Disease Q8N3Y3 E37K Neutral Neutral Q15274 A158V Neutral Neutral O95159 R218Q Neutral Neutral Q6GTX8 E63D Neutral Disease Q2UY09 T327S Neutral Disease Q2UY09 R741Q Neutral Neutral Q2UY09 I239V Neutral Neutral Q2UY09 E433D Neutral Neutral Q2UY09 A472P Neutral Disease Q2UY09 A189G Neutral Neutral P28749 I1035M Neutral Neutral Q2M2I8 K509Q Neutral Neutral Q2M2I8 Q533H Neutral Disease Q2M2I8 D835G Neutral Neutral Q2M2I8 V603A Neutral Neutral Q2M2I8 P725T Neutral Neutral Q2M2I8 I59V Neutral Neutral Q2M2I8 T694M Neutral Neutral Q2M2I8 P771R Neutral Neutral Q13336 E44K Neutral Neutral Q13336 D280N Neutral Neutral Q6B0I6 R405Q Neutral Neutral Q9UNM6 S13N Neutral Neutral Q9UNM6 G204E Neutral Neutral Q9UNM6 L205F Neutral Neutral P45379 N279Y Neutral Disease P45379 R102W Disease Disease P45379 I89N Disease Disease P45379 N281I Disease Neutral P45379 K263R Neutral Neutral P45379 R104L Disease Disease P45379 F120V Disease Disease P45379 R139K Neutral Neutral P45379 E173K Disease Neutral P45379 R151W Disease Disease P45379 F120I Disease Disease P45379 R288C Disease Neutral P45379 R140K Neutral Neutral P45378 R74H Disease Disease P45379 S189F Disease Disease P45379 S249T Neutral Neutral P45379 R296C Disease Disease P45379 R102L Disease Disease P45379 A114V Disease Neutral P45379 R288P Disease Disease P45379 F80L Disease Neutral P45379 E254D Disease Neutral P45379 R102Q Disease Neutral Q2NKK8 V240E Neutral Neutral Q2NKK8 D317N Neutral Neutral Q2NKK8 H418Y Neutral Neutral Q2NKK8 Q560E Neutral Neutral Q5VXM1 G244R Neutral Disease Q9UBR2 P36S Neutral Neutral Q9UBR2 A286T Neutral Neutral Q8NG31 K1285E Neutral Neutral Q8NG31 T43R Neutral Neutral Q8NG31 A113T Neutral Neutral Q8NG31 S486A Neutral Neutral Q8NG31 T1473A Neutral Neutral Q8NG31 G936R Neutral Disease Q8NG31 T70A Neutral Neutral Q96DT5 R3004Q Disease Disease Q96DT5 A3474T Neutral Neutral Q96DT5 A1038T Neutral Neutral Q96DT5 I2682V Neutral Neutral Q9UFH2 D492N Neutral Neutral Q96DT5 V1023A Neutral Neutral Q96DT5 S3765P Neutral Disease Q96DT5 S654C Neutral Disease Q96DT5 S2641N Neutral Neutral Q96DT5 L3715V Neutral Neutral Q96DT5 T4177I Neutral Neutral Q96DT5 Q639R Neutral Neutral Q96DT5 D1640G Neutral Disease Q13620 R554C Disease Disease Q13620 L85P Neutral Neutral Q13620 T195I Disease Neutral Q13620 V727A Disease Disease P02795 A42V Neutral Neutral P47944 R31W Neutral Neutral P47944 C30Y Neutral Neutral Q8N339 T20K Neutral Neutral P47944 G48D Neutral Neutral Q9NSE7 S228N Neutral Neutral Q03252 R215Q Disease Neutral Q03252 A407T Disease Neutral P20700 A501V Neutral Neutral Q15021 V797M Neutral Neutral Q15021 E83Q Neutral Neutral Q8N387 I184T Neutral Neutral Q8N387 T202I Neutral Neutral P32019 T745M Neutral Neutral Q9NQ31 R23K Neutral Neutral A5X5Y0 A430T Neutral Neutral A5X5Y0 A71T Neutral Neutral Q7RTS5 R64Q Neutral Neutral Q7RTS5 S199P Neutral Neutral Q7RTS5 R146Q Neutral Neutral Q96G61 S39N Neutral Disease Q96EP1 V580M Neutral Neutral Q96EP1 G270R Neutral Neutral Q96EP1 A497V Neutral Neutral Q96EP1 A456V Neutral Neutral Q9H7P9 A1329P Neutral Neutral Q9H7P9 T540I Neutral Neutral Q9H7P9 A1302T Neutral Neutral Q9H7P9 R647H Neutral Neutral Q9H7P9 I622V Neutral Neutral Q9H7P9 K992R Neutral Neutral Q8WUY9 R332M Neutral Neutral Q8WUY9 V395L Neutral Disease Q9NZ20 L157V Neutral Disease Q9NZ20 A70S Neutral Neutral Q9NZ20 E116Q Neutral Neutral Q9NZ20 R378Q Neutral Neutral Q9NZ20 S322R Neutral Neutral Q8WWG9 G47S Neutral Disease Q8WWG9 E145D Neutral Neutral O95873 R68G Neutral Neutral Q9H943 M510T Neutral Neutral Q9H943 A388G Neutral Neutral Q9H943 I607V Neutral Neutral Q8WUD6 F162S Neutral Neutral Q9NNX6 L242V Neutral Neutral Q9NNX6 E214D Neutral Neutral Q9H2X3 D291N Neutral Neutral Q8NE22 K209E Neutral Neutral Q8NE22 T76S Neutral Neutral O94919 V350M Neutral Neutral O94919 G446V Neutral Disease P53539 G33S Neutral Neutral Q9UBM1 V175M Neutral Neutral Q9UBM1 V58I Neutral Neutral A0AVF1 D310N Neutral Neutral P03897 N10D Neutral Disease P03897 M53V Neutral Disease P03897 T114A Neutral Neutral P03897 A47T Disease Disease Q9BVC3 H376R Neutral Neutral O15061 E612A Neutral Neutral O15061 R946W Neutral Neutral O15061 P761L Neutral Neutral O15061 R338W Neutral Disease O15061 A272V Neutral Neutral O15061 R1067P Neutral Disease O15061 P1059L Neutral Neutral O15061 G1386E Neutral Neutral O15061 P567L Neutral Neutral O15061 Q976R Neutral Neutral O15061 V330I Neutral Neutral O15061 F1462C Neutral Neutral O15061 S1077L Neutral Neutral P48553 I633M Neutral Neutral P48553 V726M Neutral Neutral P48553 V257E Neutral Neutral P29083 P366S Neutral Neutral Q96I82 G255A Neutral Neutral Q96I82 C76G Neutral Disease Q96I82 G236D Neutral Neutral Q8IZJ3 I1268T Neutral Neutral Q8IZJ3 D539E Neutral Neutral Q8IZJ3 R251W Neutral Neutral Q8IZJ3 P736H Neutral Neutral Q8IZJ3 T265M Neutral Neutral Q8IZJ3 H546R Neutral Neutral Q8IZJ3 Q1843R Neutral Neutral Q8IZJ3 V1156I Neutral Neutral Q8IZJ3 Q294R Neutral Neutral Q00973 G172R Neutral Neutral Q00973 L35V Neutral Neutral Q6YP21 S206P Neutral Neutral Q9H5H4 E181D Neutral Neutral Q6ZVH7 R167Q Neutral Neutral Q6ZVH7 Q829R Neutral Neutral Q6ZVH7 I568V Neutral Neutral Q6ZVH7 A761V Neutral Neutral Q6ZVH7 A574S Neutral Neutral O95965 A154S Neutral Neutral Q9H981 T56I Neutral Neutral P23378 A283P Disease Disease P23378 R515S Disease Disease P23378 S564I Disease Disease Q6ZSJ8 P39Q Neutral Neutral P52803 N55K Neutral Disease Q8N8W7 A97V Neutral Neutral Q8N8W4 S522P Neutral Neutral Q8N8W4 H423P Neutral Neutral Q8N8W4 T490M Neutral Neutral Q9BSH5 G146E Neutral Neutral Q8N302 L471P Neutral Disease Q8N302 T180A Neutral Neutral Q8N302 P698T Neutral Neutral Q8N302 E133K Disease Neutral Q99944 A204E Neutral Neutral Q99944 R86K Neutral Neutral Q9UHF1 V153I Neutral Neutral Q86XM0 T504A Neutral Neutral Q86XM0 T743S Neutral Neutral O95944 V223M Neutral Neutral O95944 P139S Neutral Neutral O95944 I218K Neutral Neutral O95944 M75V Neutral Neutral P07996 T523A Neutral Neutral P07996 N700S Neutral Neutral P05165 M204K Disease Disease P05165 G606R Disease Disease Q96RQ3 R385S Disease Disease Q96RQ3 M325R Disease Neutral P05165 R52W Disease Disease P05165 D343G Disease Disease P05165 P398L Disease Disease Q96RQ3 H464P Neutral Neutral Q96RQ3 L437P Disease Disease P05165 V526F Neutral Neutral P05165 G172E Disease Disease Q96RQ3 N560T Neutral Neutral P05165 Q272R Disease Disease P05165 I139T Disease Disease Q96RQ3 S535F Disease Disease Q96RQ3 A289V Disease Disease P05165 G643R Disease Disease P05165 I450V Neutral Neutral P05165 A113T Disease Disease P05165 C373R Disease Disease Q96RQ3 D532H Disease Disease P05165 A50P Disease Disease P05165 R374Q Disease Disease P05165 G354V Disease Disease P05165 W534L Disease Disease P05165 M348K Disease Disease P61769 A11P Disease Neutral Q96NL6 C441S Neutral Neutral Q9P1Z9 L373H Neutral Disease Q9P1Z9 D1518N Neutral Neutral Q9P1Z9 P301H Neutral Disease Q9P1Z9 S995C Neutral Neutral Q9P1Z9 F1146L Neutral Neutral Q9P1Z9 S322R Neutral Neutral Q9P1Z9 E917K Neutral Neutral P46059 G419A Neutral Neutral P46059 S117R Neutral Neutral P46059 V21I Neutral Neutral P46059 V122M Neutral Neutral P46059 V450I Neutral Neutral P46059 P537S Neutral Neutral P46059 F28Y Neutral Disease P46059 T451N Neutral Neutral P46059 S117N Neutral Neutral P46059 R459C Neutral Neutral P32745 A33V Neutral Neutral P32745 R414H Neutral Neutral P32745 R336C Neutral Disease P32745 S411T Neutral Neutral P32745 S251F Neutral Neutral O95712 A28G Neutral Neutral O95712 R422C Neutral Neutral O95712 M470I Neutral Neutral O95712 R622H Neutral Neutral Q5VWZ2 I131M Neutral Neutral Q86WN1 N344K Neutral Neutral Q86WN1 P681L Neutral Neutral Q5SZK8 F1070S Neutral Neutral Q5SZK8 R1668H Neutral Neutral Q5SZK8 M1039K Neutral Disease Q5SZK8 E1972K Disease Disease Q5SZK8 L868V Neutral Neutral Q5SZK8 A2962V Neutral Neutral Q5SZK8 T2153S Neutral Neutral Q5SZK8 T2326I Neutral Neutral Q5SZK8 V770M Neutral Neutral Q5SZK8 I1045S Neutral Disease Q5SZK8 R2066C Neutral Disease Q5SZK8 R1840W Neutral Neutral Q8TAF8 Y127C Disease Disease Q8TAF8 T165M Disease Disease Q8TAF8 R176L Disease Disease Q562F6 G9D Neutral Neutral Q562F6 I496V Neutral Neutral Q5VZV1 N46S Neutral Neutral P50440 Q110H Neutral Neutral Q9Y2R9 V2A Neutral Neutral P78424 L492M Neutral Neutral P78424 Q184H Disease Neutral P78424 E631K Neutral Disease P78424 P191L Neutral Neutral O60938 V235G Neutral Neutral O60938 N247S Disease Disease O60938 T215K Disease Neutral Q5JSP0 V275I Neutral Neutral Q9NV44 E2G Neutral Neutral Q86VQ0 L24S Neutral Neutral Q86VQ0 D26A Neutral Neutral Q86VQ0 A546P Neutral Neutral Q86VQ0 R66Q Neutral Neutral Q86VQ0 G656D Neutral Neutral P54259 M339I Neutral Neutral Q8IV33 K46E Neutral Neutral Q8IV32 R339W Neutral Neutral Q8IV32 Q317L Neutral Neutral Q9P2E2 M402V Neutral Neutral Q9P2E2 E933D Neutral Neutral Q96S66 S368R Neutral Neutral Q9H2V7 A230P Neutral Neutral Q96LR1 Y132C Neutral Neutral Q8IWV7 G1279S Disease Neutral Q8IWV8 A1095T Neutral Neutral Q8IWV7 H136R Disease Disease Q8IWV7 K596M Neutral Neutral Q9BS40 H53R Neutral Neutral Q96RK4 R295P Disease Disease Q96RK4 M472V Disease Neutral Q96RK4 N165H Disease Disease Q96RK4 L351R Disease Disease Q96RK4 E268K Neutral Neutral Q96RK4 P503L Disease Neutral Q96RK4 L327P Disease Disease Q96RK4 I354T Neutral Neutral Q96RK4 D368G Disease Disease Q96RK4 K46R Neutral Neutral Q96RK4 A393V Neutral Neutral Q96RK4 S457I Disease Neutral Q96RK4 A364E Disease Disease Q9NR33 G17V Neutral Neutral P06744 H20P Disease Disease P06744 S278L Disease Disease P06744 R347H Disease Disease P06744 L487F Disease Disease P06744 L339P Disease Disease P06744 L517V Disease Disease P06744 R308H Neutral Disease P06744 Q343R Disease Disease P06744 E495K Disease Disease P06744 T224M Disease Disease P06744 D539N Disease Disease P06744 G159S Disease Disease P06744 R347C Disease Disease P06744 I525T Disease Neutral P06744 R472H Disease Disease P06744 T375R Disease Disease P06744 R75G Disease Disease P06744 T195I Disease Neutral P06744 A300P Disease Disease P06744 R83W Disease Disease P06744 H389R Disease Disease P06744 V101M Disease Neutral P06744 T5I Disease Disease P06744 R273H Disease Disease P06744 I208T Neutral Disease Q8IYR6 V189I Neutral Neutral Q8IZ41 R262C Neutral Neutral Q8IZP2 S71L Neutral Neutral O43610 A161T Neutral Neutral Q06830 R62G Neutral Neutral P32119 D153E Neutral Neutral Q16600 G172A Neutral Neutral Q16600 G209C Neutral Neutral Q16600 D266E Neutral Neutral Q7Z401 L284P Neutral Disease Q6NW29 I124L Neutral Neutral Q8N5S9 E375G Neutral Neutral Q5TC12 S62G Neutral Neutral P13686 V221I Neutral Neutral P13686 V148M Neutral Neutral P13686 V200M Neutral Neutral Q86XP1 V1201A Neutral Neutral Q14596 R923H Neutral Neutral Q13485 G386D Disease Disease Q13485 G352R Disease Disease Q13485 E330G Disease Disease Q13485 D493H Disease Disease Q13485 R361C Disease Disease P0C6P0 T54I Neutral Disease P0C6P0 V33A Neutral Neutral P0C6P0 C81R Neutral Neutral Q8WUT4 P138L Neutral Neutral Q5T2R2 D308E Disease Disease Q86UR1 P286L Neutral Neutral Q86UR5 R820H Disease Disease O94808 I471V Neutral Disease Q9BQ49 E38K Neutral Disease Q9NYZ3 R506W Neutral Neutral Q9NYZ3 A274T Neutral Neutral Q9NYZ3 A635T Neutral Neutral Q9NYZ3 A200V Neutral Neutral Q9NYZ3 S322N Neutral Neutral Q9NYZ3 D463E Neutral Neutral Q9NYZ3 S470L Neutral Neutral Q9NYZ3 T181A Neutral Neutral Q96M11 D211G Disease Neutral Q96M11 C31R Neutral Disease Q8NAC3 L182S Neutral Neutral O00463 N186H Neutral Neutral O00186 G433E Neutral Disease O00186 G546C Neutral Disease Q15833 V526I Neutral Neutral Q14126 R46Q Disease Disease Q14126 C507Y Disease Disease Q14126 G812C Disease Disease Q14126 R49H Disease Disease Q99538 V18I Neutral Neutral Q9HA82 A366T Neutral Neutral Q9HA82 G301S Neutral Neutral Q9HA82 R119Q Neutral Neutral Q8IU89 G370R Neutral Neutral Q09FC8 I233V Neutral Neutral Q09FC8 I229L Neutral Neutral Q09FC8 H196P Neutral Disease Q09FC8 Y241C Neutral Neutral Q09FC8 N463D Neutral Neutral P48449 L642V Neutral Neutral P48449 R175Q Neutral Disease Q8N8I7 G128S Neutral Disease Q569K6 S587A Neutral Neutral Q569K6 P191L Neutral Neutral Q8IW19 L336F Neutral Neutral Q8IW19 I100V Neutral Neutral Q86TZ1 I87S Neutral Disease Q86TZ1 T140I Neutral Neutral Q86TZ1 T376S Neutral Neutral Q86TZ1 A98T Neutral Neutral Q7RTX1 R507Q Neutral Disease Q8TE23 A574T Neutral Neutral Q7RTX1 K347E Neutral Neutral Q8TE23 S9C Neutral Neutral Q7RTX0 C757R Neutral Disease Q7RTX1 A372T Neutral Neutral Q8TE23 R838K Neutral Neutral Q8N9H9 A530V Neutral Neutral Q15813 V205A Neutral Neutral Q15813 S333T Neutral Neutral Q15813 E409G Neutral Neutral Q16236 S99P Neutral Neutral Q16236 V268M Neutral Neutral Q16236 R43Q Neutral Neutral Q8IWE2 P201L Neutral Neutral Q8IWE2 R84G Neutral Neutral Q8IWE2 R367H Neutral Neutral Q8IWE2 P116L Neutral Neutral Q8IWE2 V443I Neutral Neutral Q8WXH6 H45L Neutral Disease Q8TDM0 E56D Neutral Neutral Q9H4K7 G47S Neutral Neutral Q96B21 T59I Neutral Neutral P50219 W290G Disease Disease P50219 Q292P Disease Disease P50219 R247H Disease Disease P50219 R295W Disease Disease P50219 R294W Disease Disease P50219 T248S Disease Neutral P50219 R247G Disease Disease P50219 W290L Disease Disease P50219 R295Q Disease Disease O60939 R47H Neutral Neutral O60939 R28W Neutral Neutral Q86XJ1 P500T Neutral Neutral Q86XJ1 L461S Neutral Neutral Q8WXR4 H316L Neutral Neutral Q8WXR4 N388S Neutral Neutral Q8WXR4 S969C Neutral Disease Q8WXR4 R918Q Neutral Neutral Q8WXR4 K1082R Neutral Neutral Q8WXR4 V1137I Neutral Neutral Q8WXR4 V770I Neutral Neutral Q8WXR4 Q638P Neutral Disease Q8WXR4 E798K Neutral Disease Q8WXR4 E773G Neutral Neutral Q8WXR4 R1165C Neutral Neutral Q8WXR4 R185H Neutral Neutral Q8WXR4 N267S Neutral Neutral Q8WXR4 I275V Neutral Neutral Q8WXR4 I1092V Neutral Neutral Q8WXR4 A406T Neutral Neutral Q8WXR4 E352Q Neutral Neutral Q8WXR4 R990C Neutral Disease Q8WXR4 K309E Neutral Neutral Q8WXR4 P21S Neutral Neutral P46089 R222H Neutral Disease Q99801 R52C Neutral Neutral Q5T4F4 G191V Disease Disease Q5T4F4 V82I Neutral Neutral Q5T4F4 G138V Neutral Neutral Q9Y4Z2 R107S Disease Disease Q9Y4Z2 R93L Disease Disease O95800 C160G Neutral Disease O95800 A116T Neutral Neutral O95800 L433V Neutral Neutral P00751 A736S Neutral Neutral P06681 E318D Neutral Neutral P00751 W28R Neutral Disease P00751 R32Q Neutral Neutral P00751 R32W Neutral Neutral P00751 W28Q Neutral Disease P00751 D651E Neutral Neutral P00751 L9H Neutral Disease P00751 G252S Neutral Neutral P00751 K565E Neutral Neutral P06681 R734C Neutral Disease P06681 F533L Neutral Neutral Q53T59 G273R Neutral Disease Q53T59 V260M Neutral Neutral Q53T59 A388T Neutral Neutral Q53T59 P348R Neutral Neutral O43543 I221T Neutral Neutral O43543 R188H Neutral Neutral O43543 A16S Neutral Neutral O43542 G271R Neutral Disease O43542 T241M Neutral Neutral O43542 R302H Neutral Disease O43542 R94H Neutral Neutral Q5VYJ5 H843Q Neutral Neutral Q5VYJ5 P1017S Neutral Neutral Q5VYJ5 E568K Neutral Neutral Q5VYJ5 V469A Neutral Disease Q5VYJ5 D318A Neutral Neutral Q5VYJ5 V714I Neutral Neutral Q5VYJ5 S1063N Neutral Neutral Q5VYJ5 L805I Neutral Neutral Q5VYJ5 M1135R Neutral Neutral Q5VYJ5 T673M Neutral Disease Q5VYJ5 I329V Neutral Neutral Q5VYJ5 M929T Neutral Neutral Q5VYJ5 D565G Neutral Disease Q5VYJ5 K409N Neutral Disease Q5VYJ5 K789E Neutral Neutral Q96NA2 R281Q Neutral Neutral Q9HBG7 M602V Neutral Neutral Q9BU20 E86G Neutral Disease Q32NC0 T132A Neutral Neutral Q5T9Y9 N13D Neutral Neutral Q8TDR0 R239W Neutral Neutral Q8TDR0 N228S Neutral Neutral Q8TDR0 M620L Neutral Neutral O43719 G478A Neutral Neutral Q99758 L1553P Disease Disease Q99758 Q1591P Disease Disease Q99758 L101P Disease Disease Q99758 N568D Disease Disease O15229 R452C Neutral Neutral Q8TF76 C82R Neutral Neutral Q8TF76 V76E Neutral Neutral Q8TF76 T328I Neutral Neutral Q8TF76 Q301L Neutral Neutral Q8TF76 D204G Neutral Neutral Q8TF76 N422D Neutral Neutral Q8TF76 M706V Neutral Neutral Q8TF76 G283S Neutral Neutral Q8TF76 R145H Neutral Neutral Q8TF76 A378V Neutral Neutral Q9UIK4 R60W Neutral Neutral Q9UIK4 R271W Neutral Disease P04062 H201P Disease Disease P04062 N431I Disease Disease P04062 S405G Disease Neutral P04062 C381G Disease Disease P04062 I158T Disease Neutral P04062 R324H Disease Disease P04062 H294Q Disease Neutral P04062 R324C Disease Disease P04062 R296Q Disease Neutral P04062 R535C Disease Neutral P04062 R368H Neutral Neutral P04062 V391L Disease Neutral P04062 S310G Neutral Neutral P04062 T173I Disease Disease P04062 F456V Disease Disease P04062 A175E Disease Neutral P04062 G428E Disease Disease P04062 N421K Disease Disease P04062 L483P Disease Disease P04062 K452Q Disease Neutral P04062 R159Q Disease Disease P04062 G429R Disease Disease P04062 I158S Disease Disease P04062 N227S Disease Disease P04062 P440L Disease Disease P04062 R87Q Disease Disease P04062 D419H Disease Disease P04062 A129T Disease Neutral P04062 D419N Disease Disease P04062 Y352H Disease Disease P04062 F450I Disease Neutral P04062 R502C Disease Neutral P04062 G232E Disease Disease P04062 L213F Disease Neutral P04062 A380T Disease Neutral P04062 R159W Disease Disease P04062 T270R Disease Disease P04062 A495P Disease Neutral P04062 N156D Disease Neutral P04062 L509P Neutral Disease P04062 F255Y Disease Neutral P04062 D448H Disease Neutral P04062 Y451H Disease Disease P04062 S235P Disease Disease P04062 P454R Disease Disease P04062 F290L Disease Disease P04062 F252I Disease Disease P04062 I441T Disease Disease P04062 V54L Disease Disease P04062 L224F Disease Disease P04062 K118N Disease Neutral P04062 M92T Neutral Neutral P04062 H490R Disease Neutral P04062 M400I Disease Disease P04062 A485P Disease Neutral P04062 P430L Disease Disease P04062 Y402C Disease Disease P04062 W417G Disease Disease P04062 Y343C Disease Disease P04062 P426L Disease Neutral P04062 Y457C Disease Disease P04062 Y251H Disease Disease P04062 W351C Disease Disease P04062 G152E Disease Disease P04062 T408M Disease Neutral P04062 S146L Disease Disease P04062 D438Y Disease Disease P04062 I200N Disease Disease P04062 L363P Disease Disease P04062 G517S Disease Neutral P04062 W223R Disease Disease P04062 P198T Disease Disease P04062 I200S Disease Disease P04062 G364R Disease Neutral P04062 A229T Disease Neutral P04062 K237E Disease Disease P04062 Y244C Disease Disease P04062 R392G Disease Neutral P04062 G241R Disease Neutral P04062 D179H Disease Neutral P04062 L303I Disease Disease P04062 A357D Disease Disease P04062 K342I Disease Disease P04062 K464E Disease Disease P04062 R209C Disease Disease P04062 E80K Disease Neutral P04062 N409S Disease Disease P04062 F76V Disease Disease P04062 G416S Disease Disease P04062 D63N Disease Disease P04062 R209P Disease Neutral P04062 D438N Disease Disease P04062 R170C Disease Neutral P04062 A229E Disease Neutral P04062 P161S Disease Disease P04062 P305R Disease Disease P04062 F298L Disease Disease P04062 R502P Disease Disease P04062 P198L Disease Disease P04062 S403T Disease Neutral P04062 M162V Disease Disease P04062 T362I Disease Neutral P04062 T530I Disease Disease P04062 F436S Disease Disease P04062 V414L Disease Disease P04062 R535H Disease Neutral P04062 M455V Disease Neutral P04062 V230G Disease Neutral P04062 K196Q Disease Neutral P04062 S276P Disease Disease P04062 D448V Disease Disease P04062 S310N Disease Neutral P04062 V230E Disease Neutral P04062 P221L Disease Disease P04062 A215D Disease Disease P04062 P217S Disease Disease P04062 V437L Disease Neutral P04062 P221T Disease Disease P04062 R398Q Disease Neutral P04062 G234E Disease Disease P04062 T173P Disease Disease P04062 D354H Disease Disease P04062 G241E Disease Neutral P04062 G228V Disease Neutral P04062 D166V Disease Disease P04062 D419A Disease Disease P04062 S405N Disease Neutral P04062 N435T Disease Disease P04062 G304D Disease Disease P04062 L500P Disease Disease P04062 N227K Disease Disease P04062 P328L Disease Disease P04062 G460D Disease Disease P04062 G234W Disease Disease P04062 R170L Disease Disease P04062 R87W Disease Disease P04062 T82I Disease Neutral P04062 I441F Disease Disease P04062 N501K Disease Disease P04062 V433L Disease Neutral P04062 C55S Disease Disease P04062 R392W Disease Neutral P04062 P161L Disease Disease P04062 E365K Disease Neutral P04062 G85E Disease Disease P04062 A348V Disease Disease P04062 D513Y Disease Disease P04062 L483R Disease Disease P04062 W432R Disease Neutral P04062 E388K Disease Neutral P04062 L410V Disease Neutral Q6NSJ0 R199S Neutral Neutral Q6NSJ0 F385Y Neutral Disease Q6NSJ0 D53E Neutral Neutral Q6NSJ0 N4I Neutral Neutral Q96CK0 K54R Neutral Neutral Q5T440 G211S Neutral Neutral Q96NG3 P4S Neutral Neutral Q96NG3 A18G Neutral Neutral Q5JXC2 P142S Neutral Neutral Q5JXC2 E167K Neutral Neutral Q5JXC2 K99N Neutral Neutral O00203 L580R Disease Disease Q5TGY3 A935T Neutral Neutral Q9BYB0 A198G Neutral Neutral Q9BYB0 R12C Neutral Disease Q9BYB0 A224T Neutral Disease Q9BYB0 I245T Neutral Neutral Q9BYB0 R300C Neutral Disease P24386 Q471L Disease Neutral Q8TF50 S511F Neutral Neutral Q8TF50 V94A Neutral Neutral Q8WZ55 G10S Disease Neutral Q8WZ55 G47R Disease Disease Q8WZ55 R8W Disease Disease Q8WZ55 R8L Disease Disease P08100 H211P Disease Disease P08100 M44T Disease Disease P08100 Y178C Disease Disease P08100 E150K Disease Neutral P08100 G114D Disease Disease P08100 T342M Disease Neutral P08100 P23L Disease Disease P08100 G109R Disease Disease P08100 G90D Disease Disease P08100 R135W Disease Disease P08100 F220C Disease Neutral P08100 V104I Neutral Neutral P08100 T17M Disease Disease P04000 S180A Neutral Neutral P03999 S214P Disease Neutral P08100 P347L Disease Neutral P08100 H211R Disease Neutral P08100 G51V Disease Disease P04000 T65I Neutral Neutral P08100 R135G Disease Disease P08100 P171L Disease Disease P04000 S116Y Neutral Disease P08100 C140S Disease Neutral P08100 F45L Disease Disease P08100 G188R Disease Disease P03999 G79R Disease Disease P08100 P23H Disease Disease P08100 C110F Disease Disease P08100 V345L Disease Disease P08100 P347Q Disease Disease P08100 P347S Disease Neutral P08100 T4K Disease Disease P08100 G182S Disease Disease P08100 G106W Disease Disease P08100 L125R Disease Disease P08100 T94I Disease Neutral P04001 C203R Disease Disease P08100 A164V Disease Disease P08100 G106R Disease Disease P04000 L153M Neutral Neutral P08100 Q28H Disease Disease P08100 P267R Disease Disease P08100 C110Y Disease Disease P03999 P264S Disease Disease P04000 Y309F Neutral Disease P08100 S127F Disease Disease P08100 M207R Disease Disease P04000 I230T Neutral Neutral P08100 P53R Disease Disease P04000 A298P Neutral Disease P08100 G89D Disease Disease P08100 G188E Disease Disease P08100 L40R Disease Disease P08100 L131P Disease Disease P08100 P267L Disease Disease P08100 D190Y Disease Disease P08100 P171Q Disease Disease P08100 Y178N Disease Disease P08100 M216K Disease Disease P08100 L46R Disease Disease P08100 D190N Disease Disease P08100 T58R Disease Disease P04000 I111V Neutral Neutral P08100 P171S Disease Disease P08100 R135L Disease Disease P04000 C203R Disease Disease P04000 P307L Disease Disease P08100 P347R Disease Neutral P08100 C167R Disease Disease P08100 K296E Disease Disease P08100 A164E Disease Disease P08100 E181K Disease Disease P08100 A292E Disease Disease P08100 D190G Disease Disease P08100 C222R Disease Disease P08100 S297R Disease Disease P08100 N15S Disease Disease P08100 P347A Disease Neutral P04000 A174V Neutral Disease P08100 V87D Disease Disease P08100 V345M Disease Neutral P08100 G51R Disease Disease P08100 S186P Disease Disease Q9UHA7 Q12R Neutral Neutral Q9UHA7 G134R Neutral Neutral Q9UHA7 I63T Neutral Disease Q9NX94 A320S Neutral Neutral Q9NX94 S302P Neutral Neutral Q5T4H9 R73P Neutral Neutral Q5H8A4 C610R Neutral Neutral Q5H8A4 V699I Neutral Neutral Q5H8A4 F932S Neutral Neutral Q5H8A4 R458H Neutral Neutral O00253 A67T Neutral Neutral Q6UXH0 R147Q Neutral Neutral Q6UXH0 R59W Neutral Disease P35247 L123V Neutral Neutral P35247 S290T Neutral Neutral P35247 E309K Neutral Neutral P35247 M31T Neutral Neutral P35247 A180T Neutral Neutral Q8NBI5 P53L Neutral Neutral Q8TBE7 R400K Neutral Neutral Q49AH7 A103T Neutral Neutral Q49AH7 P19S Neutral Neutral Q49AH7 R81H Neutral Neutral Q8NEP7 N288S Neutral Neutral Q8NEP7 S171R Neutral Neutral Q04671 K614N Disease Neutral Q04671 T404M Disease Disease Q04671 W679R Disease Disease Q04671 W652R Disease Disease Q04671 P198L Disease Disease Q04671 A787V Disease Disease Q04671 N489D Disease Disease Q04671 M446V Disease Neutral Q04671 W679C Disease Disease Q04671 P211L Disease Neutral Q04671 T592I Disease Neutral Q04671 S86R Disease Neutral Q04671 M395L Disease Disease Q04671 G27R Disease Neutral Q04671 R720C Disease Neutral Q04671 I473S Disease Disease Q04671 A724P Disease Disease Q04671 G795R Disease Disease Q04671 A334V Disease Disease Q04671 A481T Disease Disease Q04671 R290G Disease Disease Q04671 P743L Disease Disease Q04671 R10W Disease Neutral Q04671 Q799H Disease Neutral Q04671 M394I Disease Disease Q04671 I617L Disease Disease Q04671 A368V Disease Neutral Q04671 K614E Disease Neutral Q04671 R419W Disease Disease Q04671 V443I Disease Disease Q04671 C112F Disease Disease Q04671 F385I Disease Disease Q04671 H549Q Disease Neutral Q04671 S736L Disease Disease Q9P2R7 S199T Neutral Neutral Q3SYG4 G141R Disease Disease Q3SYG4 A455V Neutral Neutral Q63HN8 H2764R Neutral Neutral Q63HN8 S407N Neutral Neutral Q63HN8 K2805E Neutral Neutral Q63HN8 V3101I Neutral Neutral P13807 I108M Neutral Disease P13807 K130E Neutral Disease P54840 S483P Disease Disease P13807 E619Q Neutral Disease P54840 M491R Disease Disease P54840 N39S Disease Disease P13807 P691A Neutral Neutral P13807 N283S Neutral Disease P13807 M416V Neutral Neutral P54840 A339P Disease Disease P54840 H446D Disease Disease P54840 P479Q Disease Disease P13807 E359G Neutral Disease Q86UB9 R218G Neutral Neutral Q86UB9 G430A Neutral Neutral Q86UB9 H193P Neutral Neutral Q53RE8 A113T Neutral Neutral Q07869 A268V Neutral Neutral Q07869 R409T Neutral Disease Q07869 L162V Neutral Neutral Q07869 R127Q Neutral Disease Q07869 V227A Neutral Neutral Q07869 D304N Neutral Disease Q8NER1 I585V Neutral Neutral Q8N3T1 H510Y Neutral Neutral Q8NCL4 V423I Neutral Neutral Q9P0K8 P310S Neutral Neutral Q2M389 V323L Neutral Neutral Q2M389 I901V Neutral Neutral Q13415 K456E Neutral Neutral Q13415 Q180H Neutral Neutral Q13415 T466M Neutral Neutral Q13415 A372V Neutral Neutral Q13415 R441M Neutral Neutral Q13415 C469Y Neutral Neutral Q13415 R19S Neutral Disease Q13415 V190M Neutral Neutral Q13410 V303A Neutral Disease O00481 S224N Neutral Neutral Q13410 T213A Neutral Neutral Q13410 D503E Neutral Neutral O00481 P456T Neutral Neutral Q8NHS4 D552Y Neutral Neutral Q8NHS4 I426V Neutral Neutral Q8NHS4 A503V Neutral Neutral Q8NHS4 A178V Neutral Neutral Q7L622 R232H Neutral Neutral Q9NXW2 E304K Neutral Neutral Q92889 G901E Neutral Neutral Q92889 E491K Disease Neutral Q92889 I695T Neutral Disease Q92889 G502R Disease Neutral Q92889 L597P Disease Disease Q92889 T556A Disease Neutral Q92889 R565T Neutral Disease Q92889 R142P Disease Disease Q92889 R479Q Disease Neutral Q92889 R443W Disease Neutral Q92889 A157V Neutral Neutral Q92889 S651P Neutral Neutral Q92889 I706T Neutral Disease Q92889 R404Q Neutral Neutral Q92889 E864G Neutral Neutral Q92889 G692D Neutral Disease Q92889 R788W Disease Disease Q92889 I862V Neutral Neutral Q92889 I214M Disease Disease Q92889 P368S Neutral Disease Q92889 I518T Disease Neutral P04080 G4R Disease Disease Q5VV67 S536G Neutral Neutral Q5VV67 P834R Neutral Neutral Q5T7N3 V935L Neutral Neutral Q5T7N3 V840A Neutral Neutral Q5T7N3 H822R Neutral Neutral Q8WU67 R3C Neutral Neutral Q96SE0 W371C Neutral Disease Q96SE0 E137D Neutral Neutral Q9BQB6 R58G Disease Neutral Q9BQB6 V29L Disease Disease Q9BQB6 V45A Disease Neutral Q9BQB6 L128R Disease Disease Q9BQB6 R98W Disease Neutral P31249 S113C Neutral Neutral Q96QB1 H561Q Neutral Neutral Q96QB1 V354M Neutral Neutral Q9Y3M8 R383P Neutral Neutral Q9Y3M8 N798S Neutral Neutral Q9Y3M8 K250R Neutral Neutral Q96QB1 V588A Neutral Neutral Q9Y3M8 T175M Neutral Neutral Q96QB1 S772C Neutral Neutral Q96QB1 E762V Neutral Disease Q96QB1 N275S Neutral Neutral Q96QB1 T522A Neutral Neutral Q99972 G367R Disease Disease Q99972 R422H Disease Neutral Q99972 C9S Neutral Disease Q99972 N480K Disease Disease Q99972 I499F Disease Disease Q99972 Y437H Disease Disease Q99972 I477S Disease Disease Q99972 R470C Disease Disease Q99972 D380A Disease Disease Q99972 F4S Neutral Neutral Q99972 R189Q Neutral Neutral Q99972 G364V Disease Disease Q99972 T377M Disease Disease Q99972 C433R Disease Disease Q99972 S393R Disease Disease Q99972 W286R Disease Disease Q99972 V53A Disease Neutral Q99972 S502P Disease Neutral Q99972 V402I Neutral Neutral Q99972 S425P Neutral Disease Q99972 T353I Disease Neutral Q99972 R422C Neutral Disease Q99972 R82H Neutral Neutral Q99972 S203F Neutral Neutral Q99972 R76K Neutral Neutral Q99972 P361S Disease Neutral Q99972 K500R Neutral Neutral Q99972 R82C Disease Neutral Q99972 T293K Disease Disease Q99972 Q19H Neutral Neutral Q99972 I465M Disease Disease Q99972 G246R Disease Disease Q99972 I477N Disease Disease Q99972 K398R Neutral Neutral Q99972 K423E Disease Disease Q99972 A445V Disease Neutral Q99972 P481T Disease Disease Q99972 V426F Disease Disease Q99972 E352K Disease Neutral Q99972 P481L Disease Disease Q99972 G12R Neutral Neutral Q99972 Y473C Neutral Disease Q99972 D380G Disease Disease Q99972 V495I Neutral Neutral Q99972 P370L Disease Disease Q99972 Q337R Disease Disease Q99972 V329M Neutral Disease Q99972 D208E Neutral Neutral Q99972 N73S Neutral Neutral Q14050 P296L Neutral Neutral Q14050 R103W Neutral Disease Q14055 T246M Neutral Neutral Q14050 R402Q Neutral Neutral Q14055 Q326R Neutral Neutral Q14055 L335V Neutral Neutral Q14050 A435E Neutral Neutral Q14055 V581I Neutral Neutral Q14055 Q326W Disease Neutral Q14050 R103Q Neutral Disease Q86Z14 R728Q Neutral Neutral Q86Z14 A747V Neutral Neutral Q86Z14 Q1020K Neutral Neutral Q9UFN0 R100Q Neutral Neutral Q7Z7A4 K481R Neutral Neutral Q7Z7A4 A525V Neutral Neutral Q7Z7A4 I426V Neutral Neutral Q7Z7A4 A535V Neutral Neutral Q8IWU4 R325Q Neutral Disease Q8IWU4 R325W Neutral Disease Q70YC4 T62A Neutral Neutral Q70YC5 S337A Neutral Neutral Q8NHQ9 V101L Neutral Neutral Q8NHQ9 N264S Neutral Neutral Q8NHQ9 E154G Neutral Neutral Q8NHQ9 N556S Neutral Neutral Q9NWY4 K174R Neutral Neutral Q9NWY4 E331D Neutral Neutral Q9Y672 S308R Disease Disease Q9Y672 S170I Disease Disease Q9Y672 S478P Disease Disease Q9Y672 Y131H Disease Neutral Q9Y672 A333V Disease Disease Q9Y672 G227E Disease Neutral Q9Y672 F304S Neutral Neutral Q9Y6Z4 Q57E Neutral Neutral Q9Y6Z4 H23D Neutral Disease Q9Y6Z4 C24R Neutral Disease Q8NI08 S399A Neutral Neutral Q8NI08 D942E Neutral Neutral Q15468 A86V Neutral Neutral Q15468 P1012R Neutral Neutral Q15468 H984R Neutral Neutral O95863 V118A Neutral Neutral O43623 D119E Disease Neutral Q12913 Q276P Disease Disease Q12913 A293T Neutral Neutral Q12913 R214C Disease Neutral Q12913 E872D Neutral Neutral Q12913 V372I Neutral Neutral Q12913 I1235T Neutral Neutral Q12913 R326Q Neutral Neutral Q0P670 Q376R Neutral Neutral Q0P670 S108A Neutral Neutral Q8TAE6 T10A Neutral Neutral Q8IXL6 G365R Disease Disease Q8IXL6 G365E Disease Disease Q8IXL6 R535W Disease Disease Q8IXL6 L374R Disease Disease Q8WXB1 T192I Neutral Neutral O00592 L196S Neutral Neutral O00592 T62R Neutral Neutral Q8WWW8 P237S Neutral Neutral Q8NHJ6 G223D Neutral Neutral Q8NHJ6 C330Y Neutral Neutral Q8NHJ6 Q414R Neutral Disease Q8NHJ6 F5L Neutral Neutral Q8NHJ6 R18S Neutral Disease Q8NHJ6 K362E Neutral Neutral Q8NHJ6 N335D Neutral Neutral Q8NHJ6 K362T Neutral Neutral Q2M2Z5 Q139H Neutral Neutral Q2M2Z5 T236M Neutral Neutral Q8IY33 A480P Neutral Neutral Q8IY33 P519L Neutral Neutral Q68CZ2 Q600H Neutral Neutral Q68CZ2 G679S Neutral Neutral Q13477 P324H Neutral Neutral O95452 T5M Disease Disease O95452 A88V Disease Disease O95452 S199T Neutral Disease O95452 V37E Disease Disease O95452 G11R Disease Disease O95452 S139G Neutral Disease Q99973 C1055R Neutral Neutral Q99973 I2486M Neutral Neutral Q99973 S1447T Neutral Neutral Q99973 V2214I Neutral Disease Q99973 C1468Y Neutral Neutral Q99973 P1195S Neutral Neutral Q99973 H2562R Neutral Neutral Q99973 P116S Neutral Neutral Q99973 N307K Neutral Neutral Q96BF3 A202P Neutral Neutral Q9BQ95 R278C Neutral Neutral Q9BQ95 G406R Neutral Neutral Q6ZTR8 T231A Neutral Neutral Q6ZTR8 S139N Neutral Neutral Q6ZTR8 D224E Neutral Neutral Q6ZTR8 V32A Neutral Neutral Q9UQF0 S307N Neutral Neutral Q9UQF0 S477F Neutral Disease Q9UQF0 V129A Neutral Neutral Q9UQF0 R138Q Neutral Neutral Q8NFZ6 C38R Neutral Neutral Q9H1L0 V27A Neutral Neutral O60811 T233N Neutral Neutral O60811 E308G Neutral Disease O60811 V67G Neutral Neutral O60811 Y225C Neutral Disease O95521 Y302C Neutral Neutral O60811 T141M Neutral Neutral O60809 T306A Neutral Neutral O60811 T72R Neutral Neutral O60811 S68W Neutral Disease O60811 C375R Neutral Neutral O60811 F316Y Neutral Neutral O60811 A128T Neutral Neutral O60811 N304Y Neutral Neutral P78395 W7R Neutral Neutral O60809 G402R Neutral Disease O95521 R375C Neutral Disease O95521 Q252E Neutral Neutral O60811 C302Y Neutral Neutral O60809 H144R Neutral Neutral O60809 K99I Neutral Disease O60811 L310M Neutral Neutral O95521 Y316F Neutral Neutral O60811 T301A Neutral Disease O43290 G485A Neutral Neutral O43290 S463A Neutral Neutral P49747 D361V Disease Disease P49747 G440R Disease Disease P49747 D420A Disease Disease P49747 C387G Disease Disease P49747 D482G Disease Disease P49747 C468Y Disease Disease P49747 G299R Disease Disease P49747 D349V Disease Disease P49747 P276R Disease Disease P49747 D290N Disease Disease P49747 W51R Neutral Neutral P49747 C328R Disease Disease P49747 D361Y Disease Disease P49747 W51L Neutral Neutral P49747 G224R Neutral Neutral P49747 G719D Disease Disease P49747 D50E Neutral Neutral P49747 R256P Neutral Disease P49747 P285R Neutral Neutral P49747 D342Y Disease Disease P49747 D472Y Disease Disease P49747 T585M Disease Disease P49747 C371S Disease Disease P49747 T585R Disease Disease P49747 G109A Neutral Neutral P49747 R256G Neutral Disease P49747 G440E Disease Disease P49747 C348R Disease Disease P49747 N523K Disease Disease P49747 N453S Disease Disease P49747 D408Y Disease Disease P49747 D518N Disease Disease P49747 D473G Disease Disease Q9BRJ9 A53P Neutral Neutral Q9Y2Y4 R174S Neutral Neutral P02144 E55K Neutral Neutral P02144 R140W Neutral Disease P02144 R140Q Neutral Neutral P02144 K134N Neutral Disease Q8IVS8 L170V Neutral Disease Q8IVS8 T394I Neutral Neutral Q96LM6 D24N Neutral Neutral Q9H307 S671G Neutral Neutral Q9NY27 S282C Neutral Neutral P35321 I61V Neutral Neutral P22528 T11I Neutral Neutral P35321 Q42H Neutral Neutral P49685 P37S Neutral Disease Q969V3 K551R Neutral Neutral Q1ED39 A266V Neutral Neutral Q13724 D239N Neutral Neutral Q13724 E236Q Neutral Disease Q13724 R486T Disease Disease Q13724 F652L Disease Disease P35713 W95R Disease Disease P35713 A104P Disease Disease P01589 I272T Neutral Neutral Q69YN2 C160Y Neutral Neutral Q69YN2 R523H Neutral Neutral Q69YN2 R526Q Neutral Neutral Q69YN2 P259L Neutral Neutral Q9H9Y2 S9G Neutral Neutral Q9UNX9 R289C Neutral Disease P48788 R174Q Disease Disease Q9UPR6 A577T Neutral Neutral Q9UPR6 S164L Neutral Neutral Q9UPR6 D589N Neutral Disease Q9UPR6 V210L Neutral Neutral Q9UPR6 P235L Neutral Neutral Q9UPR6 M183V Neutral Neutral Q6UXX5 G1170A Neutral Neutral Q6UXX5 G387R Neutral Disease Q6UXX5 W1041S Neutral Neutral Q6UXX5 R561C Neutral Disease P15502 S422G Neutral Neutral Q15003 V539A Neutral Neutral Q8N4N8 G437R Neutral Disease Q8N4N8 A112V Neutral Neutral Q8N4N8 S417P Neutral Disease Q8N4N8 G128R Neutral Neutral O95620 R230Q Neutral Neutral P48436 P108L Disease Disease P48436 R152P Disease Disease P48436 A119V Disease Disease P48436 P170R Disease Disease P48436 A158T Disease Disease P48436 H165Y Disease Disease P56693 S135T Disease Disease P48436 F154L Disease Disease P48436 F112S Disease Disease P48436 W143R Disease Disease P48436 F112L Disease Disease Q9C0D5 S251N Neutral Neutral Q9C0D5 G1511S Neutral Neutral Q9C0D5 T1573A Neutral Neutral P78540 G240R Neutral Disease Q9H347 R624Q Neutral Neutral Q9H347 M546T Neutral Neutral Q13103 S38F Neutral Neutral Q6NV75 R209H Neutral Neutral Q9NS87 A211V Neutral Neutral Q9NS87 T996S Neutral Neutral Q9NS87 L1206M Neutral Neutral Q9NS87 E1272D Neutral Neutral O60496 A152P Neutral Neutral O60496 S394A Neutral Neutral Q9P2B7 T238A Neutral Neutral Q9P2B7 L443S Neutral Disease Q14CB8 Q305R Neutral Disease P37268 L392P Neutral Disease P37268 K45R Neutral Neutral Q5VUD6 G158S Neutral Neutral Q9Y399 D112G Neutral Neutral Q9Y399 H294R Neutral Neutral Q9Y399 M158V Neutral Neutral Q9BZI7 Y160D Disease Disease Q8N554 E605D Neutral Neutral Q8N554 R263W Neutral Neutral Q8N554 R351W Neutral Neutral P37108 P124A Neutral Neutral P37108 A127T Neutral Neutral P37108 T130A Neutral Neutral P37108 S68I Neutral Disease P37108 T125A Neutral Neutral P37108 P51S Neutral Neutral P50995 R230C Neutral Disease P50995 I457V Neutral Neutral Q9UKI9 R152H Neutral Neutral Q9Y383 D361E Neutral Neutral Q9Y3B9 K230R Neutral Neutral Q9Y3B9 K149N Neutral Neutral O75339 S1166G Neutral Neutral O75339 I395T Neutral Neutral O75339 V1168A Neutral Neutral O75339 R979Q Neutral Neutral O75339 L59W Neutral Neutral O75339 D1101N Neutral Neutral O75339 A895V Neutral Neutral O75339 E575K Neutral Neutral O75339 S327F Neutral Neutral P36888 D358V Neutral Neutral P36888 D324N Neutral Disease P36888 T227M Neutral Neutral P36888 D7G Neutral Neutral P36888 V557I Neutral Neutral P36888 V158A Neutral Neutral Q8NBU9 L105F Neutral Neutral P78508 R271C Neutral Disease P78508 R271H Neutral Neutral Q9Y6M9 P146S Neutral Neutral P08243 V210E Neutral Neutral Q9NXG2 E311D Neutral Neutral Q9NSC5 S342R Neutral Neutral Q9UL01 T25I Neutral Neutral P78504 C731S Disease Disease P78504 Y181N Disease Disease P78504 C693Y Disease Disease P78504 C714Y Disease Disease P78504 C229G Disease Disease P78504 P129R Disease Disease P78504 A31V Disease Neutral P78504 R184H Disease Disease P78504 R252G Disease Neutral P78504 C92Y Disease Disease P78504 C284F Disease Disease P78504 C271R Disease Disease P78504 P123S Disease Disease P78504 G33S Disease Disease P78504 I120N Disease Disease P78504 W224C Disease Disease P78504 I152T Disease Disease P78504 P163R Disease Disease P78504 S913R Disease Neutral P78504 C902S Disease Disease P78504 P163L Disease Disease P78504 C220F Disease Disease P78504 R818K Neutral Neutral P78504 C438F Disease Disease P78504 R184L Disease Disease P78504 L79H Disease Disease P78504 R937Q Disease Neutral P78504 F75S Disease Disease P78504 P269L Disease Neutral P78504 C911Y Disease Disease P78504 C78S Disease Disease Q9Y219 E501K Neutral Disease P78504 C92R Disease Disease P78504 P871R Neutral Disease P78504 A155P Disease Neutral P78504 C229Y Disease Disease P78504 C187S Disease Disease P78504 G256S Disease Disease P78504 A127T Disease Neutral P78504 G33D Disease Disease P78504 R889Q Disease Neutral P78504 I39S Disease Disease P78504 R184C Disease Disease P78504 C753R Disease Disease P78504 N504S Disease Disease P78504 G274D Disease Disease P78504 C740R Disease Disease P78504 G33V Disease Disease P78504 L37S Disease Disease P78504 C187Y Disease Disease P78504 G386R Disease Neutral P78504 W288C Disease Neutral P78504 R184G Disease Disease P78504 L40P Disease Disease Q05996 G36V Neutral Neutral P10163 P200H Neutral Neutral P10163 P272A Neutral Neutral P10163 P186R Neutral Neutral P10163 R185G Neutral Neutral O43493 Q105P Neutral Neutral O43493 R259W Neutral Neutral O43493 L10V Neutral Neutral O43493 Q91L Neutral Neutral O43493 K103Q Neutral Neutral O43493 A86G Neutral Neutral O43493 E322G Neutral Neutral Q2TAL5 A162T Neutral Neutral Q8TDN2 L533V Neutral Neutral Q8TDN2 G459D Disease Disease Q8TDN2 A259V Disease Disease Q8TDN2 W188C Disease Disease Q8TDN2 S256W Disease Disease Q8TDN2 L126Q Disease Disease P45877 N190S Neutral Neutral Q6UXG3 T228A Neutral Neutral Q6UXG3 D221N Neutral Neutral O95833 P38H Neutral Neutral Q6PGQ1 I4T Neutral Disease O94874 V137F Neutral Neutral Q49AR2 D405E Neutral Neutral Q49AR2 T235P Neutral Neutral Q6AWC2 A1189T Neutral Neutral Q6AWC2 A773S Neutral Neutral Q6AWC2 V816F Neutral Neutral Q6AWC2 D904H Neutral Neutral Q7Z7L8 R110S Neutral Neutral Q7Z7L8 R144C Neutral Neutral Q7Z7L8 F151S Neutral Disease Q7Z7L8 P47S Neutral Neutral Q7Z7L8 P352S Neutral Neutral Q7Z7L8 A26T Neutral Disease Q9NZ43 S154L Neutral Neutral Q9BUL8 D102A Neutral Neutral O60469 D232E Neutral Neutral Q86TC9 S691N Neutral Neutral Q86TC9 S707N Neutral Neutral Q86TC9 S803R Neutral Disease Q15726 Q36R Neutral Neutral Q15726 P81R Neutral Neutral Q15726 E20K Neutral Disease Q13608 R812W Disease Disease Q13608 R812Q Disease Disease Q9HC29 E843K Disease Neutral Q9HC29 N289S Neutral Neutral Q9HC29 L348V Disease Disease Q9HC29 L469F Disease Disease Q9HC29 R311W Disease Disease Q9HC29 T189M Neutral Neutral Q9HC29 A755V Disease Neutral Q9HC29 G924D Disease Disease Q9HC29 R235C Disease Neutral Q9HC29 V955I Neutral Neutral Q9HC29 E441K Disease Neutral Q9HC29 A140T Disease Neutral Q9HC29 H496L Disease Neutral Q9HC29 D291N Disease Neutral Q9HC29 R471C Neutral Disease Q9HC29 N414S Disease Neutral Q9HC29 L248R Disease Disease Q9HC29 R334Q Disease Neutral Q9HC29 T294S Disease Disease Q9HC29 A432V Disease Neutral Q9HC29 A612T Disease Disease Q9HC29 R702W Disease Neutral Q9HC29 A885T Disease Disease Q9HC29 N853S Disease Disease Q9HC29 A758V Disease Neutral Q9HC29 R703C Disease Disease Q9HC29 A725G Disease Neutral Q9HC29 A301V Disease Disease Q9HC29 R790Q Neutral Neutral Q9HC29 L81V Neutral Neutral Q9HC29 D382E Disease Disease Q9HC29 M863V Disease Neutral Q9HC29 V793M Disease Neutral Q9HC29 A918D Disease Disease Q9HC29 R373C Disease Disease Q9HC29 E383K Disease Disease Q9HC29 A612V Disease Disease Q9HC29 S431L Disease Neutral Q9HC29 P268S Neutral Neutral Q9HC29 R684W Disease Disease Q9HC29 R334W Disease Disease Q9HC29 W157R Disease Neutral Q9HC29 R713C Disease Disease Q9HC29 H352R Disease Neutral Q9HC29 E778K Disease Neutral Q9HC29 G908R Disease Disease P00973 S162G Neutral Neutral O60500 E117K Neutral Neutral O60500 R408Q Neutral Neutral O60500 N1077S Neutral Disease Q96C24 V420I Neutral Neutral Q8TDW5 I275V Neutral Neutral Q9UNI6 A51E Neutral Disease Q2YD98 R391H Neutral Neutral Q2YD98 L620P Neutral Neutral Q9Y6C5 T988M Neutral Neutral Q9Y6C5 I1121M Neutral Neutral Q9Y6C5 H622Y Neutral Neutral Q9Y6C5 E493K Neutral Neutral Q9Y6C5 E346Q Neutral Disease Q9Y6C5 V1019M Neutral Neutral Q96MN2 P390Q Neutral Neutral Q96MN2 R708H Neutral Neutral Q96MN2 L774M Neutral Neutral Q96MN2 E383D Neutral Neutral Q96MN2 Q925L Neutral Disease Q96MN2 A144T Neutral Neutral Q8N884 P261H Neutral Neutral Q8WZ69 F100S Neutral Disease O96017 R180H Disease Disease O96017 R406H Neutral Neutral O96017 E239K Disease Neutral O96017 R181C Disease Disease O96017 E64K Disease Neutral O96017 R180C Disease Disease O96017 I448S Neutral Neutral O96017 L512V Neutral Neutral O96017 D347N Neutral Disease O96017 I157T Neutral Disease O96017 R145P Disease Disease O96017 L436M Neutral Disease O96017 E501K Neutral Neutral O96017 Y327C Disease Neutral O96017 S500C Neutral Neutral O96017 N446K Neutral Neutral O96017 G167R Disease Disease O96017 R181H Disease Disease O96017 A17S Disease Neutral O96017 T323P Disease Disease O96017 I251F Disease Disease O96017 F447I Neutral Disease O96017 P85L Disease Neutral O96017 T476K Disease Disease O96017 R318H Disease Neutral O96017 R145W Disease Disease O96017 T59K Disease Neutral Q7L3T8 N235S Neutral Neutral Q86VB7 V342I Neutral Neutral O94913 Q651H Neutral Neutral O94913 E1402K Neutral Neutral O94913 H1119Y Neutral Neutral Q8N7X2 S126G Neutral Neutral Q8TBF4 P131Q Neutral Neutral Q00532 K341N Neutral Neutral Q00532 L329V Neutral Neutral Q00532 L66P Neutral Disease Q00532 Q274E Neutral Neutral Q13835 I196V Neutral Neutral Q13835 R116H Neutral Neutral Q13835 C161Y Neutral Neutral Q9UJ70 A60V Neutral Neutral Q9UJ70 W38R Neutral Disease Q96HA9 C91W Neutral Neutral Q9NZM3 A1533T Neutral Neutral Q9NZM3 T253A Neutral Neutral Q9NZM3 V290I Neutral Neutral Q9NZM3 I1286T Neutral Disease P29084 K183R Neutral Neutral P30279 G268R Neutral Neutral P30281 S259A Neutral Neutral P30281 E253D Neutral Neutral P30281 P134S Neutral Neutral Q8WV16 R439I Neutral Disease Q8WV16 K193T Neutral Neutral Q8WV16 W22C Neutral Disease Q8WV16 N266S Neutral Neutral Q8WV16 L334F Neutral Neutral Q8WV16 S345C Neutral Neutral Q6Y288 E370K Neutral Neutral O95759 R836G Neutral Neutral O95759 M865V Neutral Neutral O95759 G711R Neutral Disease Q7Z3Z3 P375S Neutral Disease Q96J94 K491N Neutral Neutral Q7Z3Z3 C412R Neutral Neutral Q7Z3Z4 Q78R Neutral Neutral Q96J94 L575P Neutral Disease Q7Z3Z4 Q327L Neutral Disease Q96J94 R527K Neutral Neutral Q7Z3Z3 M418V Neutral Neutral Q8N6K7 E94K Neutral Neutral Q8N841 E664D Neutral Neutral Q9H237 R365G Disease Disease Q9H237 G60R Disease Disease Q2NKQ1 T802P Neutral Neutral Q2NKQ1 R873K Neutral Neutral P23760 Q391H Disease Neutral P23760 G48R Disease Disease P23760 R270C Disease Disease P23760 R56L Disease Disease P23760 G81A Disease Disease P23760 I59F Disease Disease P23760 Y90H Disease Disease P23760 V78M Disease Disease P23760 R271H Disease Disease P23760 S84F Disease Disease P23760 W266C Disease Neutral P23760 K85E Disease Disease P23760 F238S Disease Disease P23760 F45L Disease Disease P23760 V265F Disease Disease P23760 N47H Disease Disease P23760 S73L Disease Disease P23760 N47K Disease Disease P23760 P50L Disease Disease P23760 G99D Disease Disease P23760 V60M Disease Disease P23760 T315K Neutral Neutral P23760 R271G Disease Disease P23760 I59N Disease Disease P23760 M62V Disease Disease P23760 R271C Disease Disease Q9NZK5 H335R Neutral Neutral P43005 A27G Neutral Neutral P43005 F50Y Neutral Neutral P43003 P290R Disease Disease P43003 E219D Neutral Neutral Q9NPI8 P320L Neutral Neutral Q8IU99 L86P Neutral Neutral P15735 V106E Disease Disease P15735 D215N Disease Disease P15735 E157K Disease Disease P15735 A317T Neutral Disease P15735 G189E Disease Disease Q7RTN6 S60I Neutral Disease Q7RTN6 R13W Neutral Neutral Q7RTN6 P64S Neutral Neutral Q8NCU4 R374W Neutral Neutral Q8NCU4 E696D Neutral Neutral Q9BV73 Q995H Neutral Neutral Q9BV73 R1441Q Neutral Neutral Q53RD9 V119M Neutral Neutral Q9ULD0 D573N Neutral Neutral Q9ULD0 T637M Neutral Neutral Q9ULD0 P511L Neutral Disease Q9ULD0 S623C Neutral Neutral Q9ULD0 N725S Neutral Disease Q96NL8 P19A Neutral Neutral Q9H089 K267E Neutral Neutral Q9H089 L92P Neutral Disease Q8IWZ6 H323R Disease Neutral Q8IWZ6 T211I Disease Disease Q8IWZ6 I66F Disease Neutral Q9BVX2 S175F Neutral Neutral Q9NQL9 N261T Neutral Neutral Q9NQL9 A164T Neutral Neutral Q9NQL9 G356V Neutral Neutral P28370 Q656R Neutral Disease Q6P7N7 R77Q Neutral Neutral Q6P7N7 F100S Neutral Neutral Q5BJH7 P56S Neutral Neutral O00560 N69S Neutral Neutral Q08117 A168E Neutral Disease Q86YN6 R265Q Neutral Neutral Q86YN6 V279I Neutral Neutral Q86YN6 A203P Neutral Neutral Q86YN6 R292S Neutral Neutral Q9GZV1 A62T Neutral Neutral Q7L592 P39A Neutral Neutral Q5T089 H330Y Neutral Neutral Q14997 S1371T Neutral Neutral Q14997 I872V Neutral Neutral Q86WU2 R233K Neutral Disease Q01860 M357L Neutral Neutral Q01860 T322A Neutral Neutral O95900 V93L Neutral Neutral Q96QU1 S19A Neutral Neutral Q96QU1 G262D Disease Neutral Q96QU1 G380S Neutral Disease Q96QU1 D435A Neutral Neutral Q96QU1 R134G Disease Disease Q96QU1 Q1342K Disease Disease Q96QU1 R929Q Neutral Neutral Q9H4B0 A229P Neutral Disease Q9P2V4 S591G Neutral Neutral P34969 T92K Neutral Disease P34969 P279L Neutral Disease Q9BVC5 G185D Neutral Neutral Q8TCC3 A130T Neutral Neutral Q5VYV7 R317Q Neutral Neutral P54278 P470S Neutral Neutral P54278 R20Q Neutral Neutral P54278 T597S Neutral Neutral P54278 H479Q Neutral Neutral P54278 T485K Neutral Neutral P54278 E541K Neutral Neutral P54278 E705K Disease Disease P54278 T511A Neutral Neutral P54278 N775S Neutral Neutral P54278 T277K Neutral Neutral P54278 M622I Neutral Neutral Q96JQ5 M178V Neutral Neutral P35573 R387Q Neutral Neutral P35573 Q229R Neutral Neutral P35573 R1253H Neutral Neutral P35573 G1448R Disease Disease P35573 I1144N Neutral Disease P35573 A701S Neutral Neutral P35573 R1487G Neutral Neutral P35573 T38A Neutral Neutral P35573 P1067S Neutral Disease P35573 G1115R Neutral Disease P35573 E1343K Neutral Neutral P35573 S962C Neutral Neutral O15118 N1156S Disease Disease O15118 H215R Neutral Neutral O15118 G992W Disease Neutral O15118 A1035V Disease Disease O15118 C956Y Disease Disease O15118 R1266Q Neutral Neutral O15118 I858V Neutral Neutral O15118 T1036M Disease Disease O15118 F1167L Disease Disease O15118 Q928P Disease Disease O15118 R978C Disease Neutral O15118 D948N Disease Neutral O15118 L1213V Disease Disease O15118 G992R Disease Neutral O15118 C177Y Disease Disease O15118 M642I Neutral Neutral O15118 S473P Disease Disease O15118 L1213F Disease Disease O15118 Y1088C Disease Disease O15118 S954L Disease Disease O15118 R958Q Disease Disease O15118 I1061T Disease Disease O15118 S940L Disease Disease O15118 V950M Disease Neutral O15118 H510P Disease Disease O15118 R518Q Disease Neutral O15118 V757A Neutral Disease O15118 I1220T Neutral Disease O15118 P1007A Disease Disease O15118 P237S Disease Neutral O15118 R934Q Disease Disease O15118 G333D Neutral Neutral O15118 V378A Disease Disease O15118 C177G Disease Neutral O15118 R1186H Disease Disease O15118 V889M Disease Neutral O15118 L472P Neutral Disease Q5T292 P83L Neutral Neutral P43080 E155G Disease Disease P43080 Y99C Disease Disease P43080 P50L Disease Neutral P10323 L120V Neutral Neutral P10323 F166L Neutral Neutral Q8IYR2 I131R Neutral Neutral Q8IYR2 R562W Neutral Neutral Q8IYR2 C727Y Neutral Neutral Q96PV6 I520V Neutral Neutral Q96PV6 R242P Neutral Neutral Q5TI25 R571C Neutral Neutral Q5TI25 S243G Neutral Disease Q8N715 L380R Neutral Neutral Q8N715 R331W Neutral Neutral Q8N715 V195A Neutral Neutral Q8N715 D329G Neutral Neutral O15305 C241S Disease Disease O15305 H195R Disease Disease O15305 F119L Disease Disease O15305 R141C Disease Disease O15305 C192G Disease Disease O15305 V67M Disease Neutral O15305 G228R Disease Disease O15305 G117R Disease Disease O15305 D217E Disease Disease O15305 Y64C Disease Disease O15305 F172V Disease Disease O15305 L32R Disease Disease O15305 P69S Disease Neutral O15305 Q37L Neutral Neutral O15305 D185G Disease Neutral O15305 F11C Disease Disease O15305 N101K Disease Disease O15305 V44L Disease Disease O15305 A233T Disease Neutral O15305 R123Q Disease Disease O15305 G228C Disease Disease O15305 D148N Disease Disease O15305 R238P Disease Disease O15305 G208A Disease Disease O15305 N216I Disease Disease O15305 Q177H Disease Disease O15305 T237M Disease Disease O15305 Y76C Disease Disease O15305 M212V Neutral Neutral O15305 I132N Disease Disease O15305 T237R Disease Disease O15305 G15E Disease Disease O15305 G42R Neutral Disease O15305 C9Y Disease Disease O15305 T226S Disease Disease O15305 C103F Disease Disease O15305 A108V Disease Disease O15305 E93A Disease Disease O15305 F144L Disease Disease O15305 D223N Disease Disease O15305 I132T Disease Disease O15305 Y106C Disease Disease O15305 V231M Disease Disease O15305 V129M Disease Disease O15305 E151G Disease Disease O15305 Q37H Disease Neutral O15305 V44A Disease Disease O15305 D223E Disease Disease O15305 R162W Disease Disease O15305 I120T Disease Disease O15305 N216S Disease Disease O15305 G175R Disease Disease O15305 Y229S Disease Disease O15305 R238G Disease Disease O15305 I132F Disease Disease O15305 P113L Disease Disease O15305 P20S Disease Neutral O15305 D65Y Disease Disease O15305 F183S Disease Disease O15305 F157S Disease Disease O15305 H218L Disease Disease O15305 D188G Disease Disease O15305 I153T Disease Disease O15305 G214S Disease Disease O15305 R141H Disease Disease O15305 E139K Disease Disease O15305 P131A Disease Disease O15305 E197A Disease Disease O15305 F206S Disease Disease O15305 L104V Disease Disease O15305 G176V Disease Disease Q5SWX8 S251C Neutral Neutral Q14161 N387S Neutral Neutral P06727 Q380H Neutral Neutral P06727 E185K Neutral Disease P06727 N147S Neutral Neutral P06727 K187E Neutral Neutral P06727 T367S Neutral Neutral P06727 Q77H Neutral Neutral P06727 V307L Neutral Neutral P06727 E250K Neutral Neutral P06727 G74S Neutral Neutral P06727 R279K Neutral Neutral P06727 V13M Neutral Neutral Q5VT06 E945Q Neutral Neutral Q96LW9 T50S Neutral Disease Q96LW9 K205R Neutral Neutral Q9GZX3 A217T Disease Neutral Q9GZX3 C102Y Disease Disease Q9GZX3 L22R Disease Disease Q9GZX3 E274K Disease Disease Q9GZX3 F107S Disease Disease Q9GZX3 M104V Disease Neutral Q9GZX3 D221E Disease Neutral Q9GZX3 R166P Disease Disease Q9GZX3 R211Q Disease Disease Q9GZX3 K174R Disease Disease Q9GZX3 A206T Disease Disease Q9GZX3 S53L Disease Disease Q9GZX3 R205L Disease Disease Q9GZX3 D221Y Disease Disease Q9GZX3 P72S Disease Disease Q9GZX3 Y110C Disease Disease Q9GZX3 G52D Disease Disease Q9GZX3 R93H Disease Disease Q9GZX3 R202S Disease Disease Q9GZX3 S51L Disease Disease Q9GZX3 N61T Disease Disease Q9GZX3 R177H Disease Disease Q9GZX3 Y68H Disease Disease Q9GZX3 N369D Neutral Neutral Q9GZS9 T297M Neutral Neutral Q9GZX3 V76M Disease Disease Q9GZX3 R97P Disease Disease Q9GZX3 R162G Disease Neutral Q9GZX3 P31S Disease Neutral Q9GZX3 L200R Disease Disease Q9GZX3 L59P Disease Disease Q9GZX3 Q122P Disease Disease Q9GZX3 P204Q Disease Disease Q9GZX3 A128V Disease Neutral Q9GZX3 D203E Disease Disease Q9GZX3 L276P Disease Disease Q9GZX3 R50C Disease Disease Q9GZX3 H249P Disease Disease Q9GZX3 S131P Disease Disease Q9GZX3 L15P Disease Disease Q9GZX3 V66L Disease Disease Q9GZX3 R127C Disease Disease Q9GZX3 M70L Disease Neutral Q9GZX3 L152P Disease Disease Q9GZX3 R205Q Disease Disease Q9GZX3 R211W Disease Disease Q9GZX3 F121L Disease Disease Q9GZX3 V198E Disease Disease Q9GZX3 S98W Disease Disease Q9GZX3 Y268C Disease Disease Q9GZX3 S210F Disease Disease Q9GZX3 C102G Disease Disease Q9GZX3 H42Y Disease Disease Q9GZX3 Y358D Disease Disease Q9GZX3 A206V Disease Disease Q14973 S267F Neutral Neutral Q5XPI4 P51R Neutral Neutral A6NK97 A58D Neutral Disease O76082 P549S Neutral Neutral O76082 M179L Disease Neutral Q8TCC7 I305F Neutral Disease O76082 Y211C Disease Disease Q6T423 S250G Neutral Neutral O15244 P54S Neutral Disease Q8TCC7 V281A Neutral Neutral O76082 F508L Neutral Disease Q6T423 R300T Neutral Disease Q96S37 R92C Neutral Neutral Q4U2R8 R50H Neutral Neutral O76082 V446F Disease Disease Q86VW1 H49R Neutral Neutral Q8TCC7 F129L Neutral Disease Q8TCC7 R277W Neutral Neutral Q86VW1 V431I Neutral Neutral Q96S37 L418R Disease Disease O76082 F17L Neutral Disease Q96S37 M430T Disease Neutral Q4U2R8 R293W Neutral Disease Q96S37 R477H Disease Disease O15244 R463K Neutral Disease Q96S37 G65W Neutral Disease Q96S37 V138M Disease Disease O76082 S467C Disease Neutral O76082 P478L Disease Disease Q96S37 A226V Neutral Neutral Q9H015 G462E Neutral Disease O75751 T44M Neutral Neutral Q8TCC7 V448I Neutral Neutral A6NK97 A139V Neutral Neutral Q8TCC7 I260R Neutral Disease Q96S37 Q382L Disease Disease O15244 A270S Neutral Neutral Q4U2R8 L7P Neutral Disease Q9Y226 V43I Neutral Neutral Q86VW1 M409T Neutral Disease Q96S37 R90H Disease Disease Q9H015 L503F Disease Neutral O15244 M165I Neutral Disease Q96S37 Q312L Neutral Neutral O76082 M530V Neutral Neutral O76082 W283R Disease Disease Q96S37 T217M Disease Neutral O76082 V481I Neutral Neutral O75751 A116S Neutral Neutral O76082 L144F Neutral Neutral O15244 R400C Neutral Disease O15244 K432Q Neutral Neutral Q8TCC7 A389V Neutral Disease O76082 R169Q Disease Disease O76082 E452K Disease Disease O76082 V481F Neutral Disease Q9Y226 L443F Neutral Disease Q9H015 I306T Neutral Neutral O15244 A297G Neutral Neutral Q86VW1 V252A Neutral Neutral O76082 W283C Disease Disease O76082 Y449D Neutral Disease Q96S37 G164S Disease Disease O15244 T201M Neutral Neutral Q96S37 E298D Disease Disease Q16851 M268I Neutral Neutral Q14839 S1648L Neutral Neutral Q14839 D139E Neutral Neutral Q14839 I1655V Neutral Neutral Q5K131 S9F Neutral Neutral P35499 T1313M Disease Neutral P35499 L1433R Disease Disease P35499 S804F Disease Disease P35499 R672G Disease Disease P35499 G1456E Disease Disease P35499 D1376N Neutral Neutral P35499 P1158S Disease Neutral P35499 R1448H Disease Disease P35499 G524S Neutral Neutral P35499 N559D Neutral Neutral P35499 R675G Disease Disease P35499 T704M Disease Neutral P35499 G1306V Disease Neutral P35499 R672S Disease Disease P35499 V1589M Disease Disease P35499 G1306A Disease Neutral P35499 V1293I Disease Neutral P35499 R669H Disease Disease P35499 R1448C Disease Disease P35499 M135V Neutral Disease P35499 A1152D Disease Disease P35499 A1156T Disease Neutral P35499 M1592V Disease Disease P35499 S246L Neutral Disease P35499 R675W Disease Disease P35499 R672H Disease Disease P35499 A861D Neutral Neutral P35499 R675Q Disease Disease P35499 G1306E Disease Neutral Q9H427 P323L Neutral Neutral Q9H427 P260T Neutral Neutral Q9H427 P261H Neutral Neutral Q9H427 G95E Neutral Disease P40939 I305N Disease Disease P40939 V282D Disease Disease P40939 L342P Disease Disease P40939 E510Q Disease Neutral Q9NS93 P179R Neutral Neutral P08253 E404K Disease Disease P08253 R101H Disease Disease O95980 V275I Neutral Neutral P43307 L28S Neutral Neutral Q8N4M1 I438V Neutral Neutral O60427 P272S Neutral Neutral Q9Y5Q0 K192N Neutral Neutral Q9Y5Q0 N216K Neutral Disease Q96FX7 V66A Neutral Neutral Q9NU63 N114S Neutral Neutral Q9NU63 D284V Neutral Neutral P31150 R423P Disease Disease P31150 L92P Disease Disease Q9Y2D5 L561S Neutral Neutral A0PJW6 V196G Neutral Disease A0PJW6 T28A Neutral Neutral Q9H5I5 V255I Neutral Neutral Q5T655 S496T Neutral Neutral Q5T655 Q804H Neutral Neutral Q6UX07 R191Q Neutral Neutral Q6UX07 L336Q Neutral Neutral Q03393 R25G Disease Disease Q03393 D96N Disease Disease Q03393 T67M Disease Disease Q03393 P87S Disease Neutral Q03393 N47D Disease Disease Q03393 V56M Disease Neutral Q03393 I114V Disease Neutral Q03393 V70D Disease Disease Q03393 R25Q Disease Disease Q03393 R16C Disease Disease Q03393 F100V Disease Disease Q03393 D136V Disease Disease Q03393 P87L Disease Neutral Q03393 N36K Disease Disease Q03393 T106M Disease Disease Q03393 N52S Disease Disease Q03393 K129E Disease Neutral Q03393 E35G Disease Disease Q03393 D116G Disease Disease Q96T21 R540Q Disease Neutral Q9BRP4 C139S Neutral Neutral Q9BRP4 A53V Neutral Neutral Q9BRP4 A209G Neutral Neutral P53985 K204E Disease Neutral P53985 E490D Neutral Neutral O60669 S445T Neutral Neutral P53985 G472R Disease Neutral Q8NEA6 Q300P Neutral Neutral Q8N4C6 E1320G Neutral Neutral Q8N4C6 P1111A Neutral Neutral Q8N4C6 S1837T Neutral Neutral P20810 E380K Neutral Neutral P20810 E592G Neutral Neutral P20810 C408S Neutral Neutral P20810 A537V Neutral Neutral Q96KM6 M372V Neutral Neutral Q96KM6 A453T Neutral Neutral Q86UV6 W13R Neutral Disease Q9H8W5 R413Q Neutral Neutral Q9H8W5 C375Y Neutral Disease Q9H8W5 M496T Neutral Neutral Q8N568 G119C Neutral Disease Q8N568 R372H Neutral Disease Q8N568 I583V Neutral Neutral Q8N1B3 C183S Neutral Disease Q14683 E493A Disease Disease Q8N3X1 E125G Neutral Neutral Q8N3X1 T794A Neutral Neutral P00533 G719D Disease Disease P00533 T790M Disease Neutral P00533 R98Q Neutral Neutral P00533 L858R Disease Disease P00533 E709K Disease Disease P00533 R748P Disease Disease P00533 P266R Neutral Neutral P00533 V674I Neutral Neutral P00533 E709A Disease Disease P00533 V834L Disease Disease P00533 H988P Neutral Disease P00533 L1034R Neutral Neutral P00533 L858M Disease Disease P00533 Q787R Disease Neutral P00533 L833V Disease Neutral P00533 L861Q Disease Neutral P00533 G719A Disease Disease P00533 G719S Disease Disease P00533 R521K Neutral Neutral P00533 G873E Disease Disease P00533 G719C Disease Disease P00533 G724S Disease Disease P00533 L747F Disease Disease P00533 E734K Disease Neutral P00533 A1210V Neutral Neutral P00533 R962G Neutral Neutral Q96EU6 A78G Neutral Neutral Q8TDP1 R69W Disease Disease Q8TDP1 K143I Disease Disease Q02962 A334V Neutral Neutral Q02962 G76S Disease Disease Q02548 A322T Neutral Neutral Q8TC20 T169I Neutral Neutral Q8TC20 E282A Neutral Neutral Q92847 A204E Disease Neutral Q7Z6J8 T174P Neutral Neutral Q7Z6J8 V379M Neutral Neutral Q9UBS5 G489S Neutral Neutral Q9UBS5 A20V Neutral Neutral Q9H5U6 L396H Neutral Neutral A2RUB6 R383Q Neutral Neutral A2RUB6 E592K Neutral Neutral A2RUB6 R460Q Neutral Neutral Q6XLA1 P8S Disease Neutral Q9BYD2 A210E Neutral Neutral Q9BYD2 E67G Neutral Neutral Q86UZ6 T11A Neutral Disease Q16654 L19M Neutral Neutral Q16654 D109G Neutral Disease Q15118 N412T Neutral Neutral Q16654 A17V Neutral Neutral Q15116 A215V Neutral Neutral O15228 V495I Neutral Neutral O15228 R211H Disease Disease O15228 Y586H Neutral Neutral O15228 D519G Disease Neutral O15228 R211C Disease Disease Q9H609 P81L Neutral Neutral Q9NYR8 M202T Neutral Neutral Q9NYR8 H136Q Neutral Neutral O00358 A65V Disease Disease O00358 S57N Disease Disease Q9HBI1 P52R Neutral Neutral Q9HBI1 V58A Neutral Neutral P04217 H395R Neutral Neutral P04217 R52H Neutral Neutral Q68D86 A429P Neutral Disease Q68D86 C346F Neutral Disease Q99732 T115N Disease Neutral Q99732 W116G Disease Disease Q99732 Y23H Disease Neutral Q99732 T49M Disease Neutral Q99732 L122V Disease Neutral Q99732 I92V Neutral Neutral Q99732 G112S Disease Disease Q38SD2 L1847F Neutral Neutral Q38SD2 D1950G Neutral Disease Q38SD2 A1826T Neutral Neutral Q38SD2 S1870N Neutral Neutral Q7Z5H5 D220N Neutral Neutral Q7Z5H5 A52V Neutral Disease Q7Z5H5 R58L Neutral Neutral Q92802 Y272H Neutral Neutral O96001 V12L Neutral Neutral P54132 C1055S Disease Disease P54132 P868L Neutral Neutral P54132 I841T Disease Disease P54132 K137R Neutral Neutral P54132 Q672R Disease Disease P54132 S1209T Neutral Neutral P54132 G891E Disease Disease P54132 V1205I Neutral Neutral P54132 C1036F Disease Disease P54132 V1321I Neutral Neutral P54132 E1213K Neutral Neutral P54132 C878R Disease Neutral P54132 T298M Neutral Neutral P54132 R591Q Neutral Neutral P54132 C901Y Disease Disease P54132 T843I Disease Neutral P30411 G354E Neutral Neutral P30411 R14C Neutral Neutral P35590 A1104V Neutral Neutral P35590 V448M Neutral Neutral Q02763 Y897S Disease Neutral P35590 R1109H Neutral Disease Q02763 R849W Disease Neutral Q9BXG8 E302K Neutral Neutral Q9BXG8 V17L Neutral Neutral Q8N660 P615Q Neutral Disease Q96E22 D179E Neutral Neutral Q96E22 N175Y Neutral Neutral Q96E22 K216R Neutral Neutral Q96E22 T219K Neutral Neutral Q9H2H8 D146E Neutral Neutral Q9HAQ2 V78I Neutral Neutral Q9HAQ2 G96A Neutral Disease Q9HAQ2 W638R Neutral Neutral P08237 G209D Disease Disease P17858 R151W Neutral Disease P08237 R39P Disease Disease P08237 W686C Disease Disease P08237 R100Q Disease Neutral P08237 R696H Disease Disease P08237 D543A Disease Disease P17858 D237V Neutral Disease P17858 G81A Neutral Disease P08237 R39L Disease Disease Q9NYV7 N172K Neutral Neutral Q9NYV7 R222H Neutral Neutral Q01974 C182Y Disease Disease Q01974 R184C Disease Disease Q01974 R189W Disease Disease Q01974 N620K Disease Disease Q01974 R366W Disease Disease P56715 N985Y Neutral Disease P56715 R872H Neutral Neutral P56715 S1691P Neutral Neutral P56715 C2033Y Neutral Neutral P56715 A1670T Neutral Neutral O60575 V7I Neutral Neutral Q5MNZ9 T31I Neutral Neutral Q9BSE5 G105R Neutral Neutral Q96MU5 S47R Neutral Neutral P20929 G5934E Neutral Neutral P20929 D5030V Neutral Neutral Q8NE35 R324W Neutral Disease Q86XP0 R747G Neutral Disease Q86XP0 A649G Neutral Neutral Q86XP0 R573W Neutral Neutral Q68DD2 V740M Neutral Neutral Q3MJ16 N370S Neutral Neutral Q3MJ16 A663T Neutral Neutral P32929 S403I Neutral Neutral P32929 T67I Neutral Disease Q02846 P858S Disease Disease P20594 Q771E Neutral Neutral Q02846 R838C Disease Disease P20594 Y708C Disease Disease Q02846 E837D Disease Disease P20594 R957C Disease Disease P20594 G413E Disease Disease Q02846 A52S Disease Neutral P20594 G959A Disease Disease P20594 P32T Disease Disease Q02846 I573V Disease Neutral P20594 V882I Neutral Neutral P20594 M232I Neutral Neutral Q02846 L954P Disease Disease P20594 W115G Disease Disease P20594 A409T Disease Neutral P20594 T297M Disease Disease P20594 R776W Disease Disease Q02846 R838H Disease Disease P20594 D176E Disease Neutral P20594 Y338C Disease Disease Q02846 L325P Disease Disease Q02846 C105Y Disease Disease Q02846 P701S Disease Neutral Q02846 F565S Disease Disease Q02846 A362S Disease Neutral Q9UG22 H161R Neutral Neutral Q9NX00 G120S Neutral Neutral Q2PZI1 G502V Neutral Neutral O43520 G892R Disease Disease O43520 G308V Disease Disease O43520 L288S Disease Disease O43520 I661T Disease Disease O43520 D554N Disease Disease Q96C10 Q425R Neutral Neutral Q96C10 R523Q Neutral Neutral O75558 L204H Neutral Disease O75558 E31Q Neutral Neutral O75558 R49Q Neutral Neutral O75558 T277A Neutral Neutral Q96SZ5 P266S Neutral Disease Q96SZ5 P39A Neutral Neutral Q96SZ5 G25W Neutral Neutral Q8NBK3 A279V Disease Disease Q8NBK3 A348P Disease Disease Q8NBK3 C336R Disease Disease Q8NBK3 P266L Disease Disease Q8NBK3 S63N Neutral Neutral Q8NBK3 S155P Disease Disease Q8NBK3 R224W Disease Disease Q8NBK3 C218Y Disease Disease Q8NBK3 R349Q Disease Disease Q8NBK3 R349W Disease Disease Q8NBK3 N259I Disease Disease Q8NBK3 W179S Disease Disease Q8NBK3 L20F Disease Neutral Q8NBK3 R345C Disease Disease Q8NBK3 A177P Disease Disease Q8IVE3 P481T Neutral Neutral Q8IVE3 R1069K Neutral Disease Q8IVE3 N1217S Neutral Neutral Q8TE73 S1006G Neutral Neutral Q8TE73 R2501P Disease Disease Q8TE73 G3519R Disease Disease Q8TE73 T4220A Neutral Neutral Q8TE73 S2264N Disease Disease Q8TE73 G4205V Disease Disease Q8TE73 G24E Neutral Neutral Q8TE73 T558A Neutral Neutral Q8TE73 A4134V Neutral Disease Q8TE73 F2843S Disease Disease Q8TE73 I766L Neutral Neutral Q8TE73 S3843L Disease Disease Q8TE73 L2862F Neutral Neutral Q8TE73 I4450V Neutral Neutral Q8TE73 E2347K Disease Disease Q8TE73 T3791I Neutral Neutral Q8TE73 H12Q Neutral Neutral Q8TE73 M1081V Neutral Neutral Q8TE73 R1716L Disease Disease Q8TE73 Q2463R Neutral Neutral Q8TE73 W3409S Disease Disease P42768 T45M Disease Disease P42768 C43W Disease Disease P42768 A134T Disease Neutral P42768 P58R Disease Neutral P42768 E31K Disease Disease P42768 G89D Disease Neutral P42768 W97C Disease Disease P42768 G70W Disease Disease P42768 P58L Disease Neutral P42768 A236E Disease Disease P42768 R477K Disease Neutral P42768 C73R Disease Disease P42768 R86H Disease Disease P42768 L270P Disease Disease P42768 S82P Disease Disease P42768 R86L Disease Disease P42768 R86C Disease Disease P42768 K476E Disease Neutral P42768 F84L Disease Disease P42768 Q52H Disease Disease P42768 E133K Disease Disease P42768 T48I Disease Disease P42768 G187C Disease Neutral P42768 L27F Disease Neutral P42768 A56V Disease Neutral P42768 E131K Disease Disease P42768 I481N Disease Neutral P42768 Y83C Disease Disease P42768 V75M Disease Neutral Q76L83 A796V Neutral Neutral Q76L83 T1210P Neutral Neutral Q76L83 L731P Neutral Neutral Q76L83 T1242P Neutral Neutral Q8N6Q8 K249Q Neutral Neutral Q9GZS0 T558A Neutral Neutral Q8NHU6 P456L Neutral Neutral Q8NHU6 V150A Neutral Neutral P59103 R30K Neutral Neutral Q9P241 V1240I Neutral Neutral Q9P241 S1389T Neutral Neutral Q8NFR7 M157V Neutral Neutral Q8NFR7 Q75R Neutral Neutral Q8NFR7 R329K Neutral Neutral Q0VAK6 A560V Neutral Neutral Q0VAK6 K438M Neutral Neutral P42685 S133L Neutral Neutral P42685 G122R Neutral Disease P42685 I100V Neutral Neutral Q13203 A114G Neutral Neutral Q13203 Q48H Neutral Neutral Q13203 A49G Neutral Neutral P07988 L176F Neutral Neutral P07988 R236C Disease Neutral P07988 T131I Neutral Neutral P07988 R272H Neutral Neutral Q15750 D224E Neutral Neutral Q8N3T6 V271I Neutral Neutral Q8N3T6 V443I Neutral Neutral Q8N3T6 V231M Neutral Neutral Q8N3T6 T729S Neutral Neutral Q14DG7 A658V Neutral Neutral Q8N3T6 H160R Neutral Neutral Q8N3T6 R809G Neutral Neutral Q8N3T6 F798I Neutral Disease Q14C87 L878F Neutral Neutral P15260 I87T Disease Neutral P15260 C77Y Disease Disease P15260 L467P Neutral Neutral P15260 V61I Neutral Neutral P15260 H335P Neutral Neutral Q13619 K644R Neutral Neutral Q13618 V567I Neutral Neutral Q13618 D13H Neutral Neutral Q9UNF0 M294I Neutral Disease Q9UNF0 V324F Neutral Disease O95704 R231C Neutral Disease O95704 G165R Neutral Disease P28300 R158Q Neutral Neutral Q86X40 R168H Neutral Disease Q9NYH9 K35R Neutral Neutral Q9NYH9 Q69R Neutral Neutral Q9NX46 E209K Neutral Neutral Q9NX45 S14L Neutral Neutral Q9NX45 A339T Neutral Neutral Q86W47 V199I Neutral Neutral Q92765 R200W Neutral Disease Q92765 R324G Neutral Neutral Q96PQ7 G508S Neutral Disease Q9UIG5 K34Q Neutral Neutral Q9UIG5 P133L Neutral Neutral Q9UIG5 P24T Neutral Neutral Q9UIG5 R37H Neutral Neutral Q96QV1 V341I Neutral Neutral Q9UHB4 V522I Neutral Neutral Q6HA08 R222Q Neutral Neutral O00574 E3K Neutral Neutral Q9H706 T720M Neutral Neutral Q9H706 K291R Neutral Neutral Q9H706 V580I Neutral Neutral Q9H706 A490V Neutral Neutral Q9H706 T243N Neutral Neutral P28907 R140W Neutral Neutral Q6P4H8 V114A Neutral Disease Q6P4H8 T75M Neutral Neutral Q6P4H8 L229M Neutral Neutral Q6P4H8 A105V Neutral Neutral Q5T890 V592A Neutral Neutral Q9H0X9 A774T Neutral Neutral Q86UE6 N330S Neutral Neutral Q7Z5L0 T77S Neutral Neutral Q495Z4 S32R Neutral Neutral Q8N9W4 R235P Neutral Neutral Q8N9W4 W191R Neutral Neutral Q8N9W4 N54H Neutral Neutral Q8N9W4 E64G Neutral Neutral Q8N9W4 R43G Neutral Neutral Q6PI47 A413V Neutral Neutral Q6PI47 A333V Neutral Neutral Q6PI47 C390S Neutral Neutral Q6PI47 G336C Neutral Neutral Q8TF71 K508Q Neutral Neutral P36021 L397P Disease Disease P36021 A150V Disease Disease P36021 L438P Disease Disease Q9UHP7 L23V Neutral Neutral Q9UHP7 N19K Neutral Neutral Q96PU5 P355L Neutral Neutral Q96PU5 S497R Neutral Disease Q8N4S0 Q327R Neutral Neutral Q8N4S0 Q149E Neutral Neutral Q9UBF9 S39F Disease Neutral Q9UBF9 S95I Disease Neutral Q9UBF9 S55F Disease Neutral Q9UBF9 T57I Disease Neutral Q9UBF9 S60F Disease Neutral Q9UBF9 S60C Disease Neutral P43363 K166R Neutral Neutral A2A368 L70F Neutral Neutral O15479 G318R Neutral Neutral A2A368 M280V Neutral Neutral O15480 T112I Neutral Neutral A2A368 C160Y Neutral Neutral Q96LZ2 R65Q Neutral Neutral A2A368 H193R Neutral Neutral O15480 H107R Neutral Neutral O15479 K61E Neutral Neutral A2A368 M280K Neutral Neutral P35858 R548W Neutral Disease P35858 P498S Neutral Disease Q6UWM7 A240T Neutral Disease Q16821 A931E Disease Neutral Q16821 D905Y Disease Neutral Q8TDD1 P821L Neutral Neutral Q8WWA0 V109D Neutral Neutral Q8WWU7 R103H Neutral Neutral Q8WWA0 R313P Neutral Disease Q6ZVZ8 A127P Neutral Disease Q15637 S357T Neutral Neutral Q9NV92 A136V Neutral Neutral Q969V6 S648G Neutral Neutral Q9NRX1 R11G Neutral Neutral Q9NRX1 G71A Neutral Neutral O94933 I605V Neutral Neutral Q8WUU5 G54S Neutral Neutral A4D1E9 L164F Neutral Neutral A4D1E9 M368I Neutral Neutral A4D1E9 N110S Neutral Neutral A4D1E9 C88W Neutral Neutral P40225 L14P Neutral Disease P40225 G116E Neutral Neutral P58499 V14M Neutral Neutral P98173 W213C Neutral Disease O95415 T123A Neutral Neutral A6NI79 R197K Neutral Neutral Q9C093 G74S Neutral Neutral Q9C093 R366K Neutral Neutral Q9C093 N71H Neutral Neutral Q9C093 R447Q Neutral Disease Q9C093 N616K Neutral Neutral Q9C093 E655G Neutral Neutral Q9C093 D500N Neutral Neutral Q9C093 K1482N Neutral Neutral Q969T4 W201R Neutral Disease P28908 S402G Neutral Neutral P28908 C273Y Neutral Disease Q86V59 S80T Neutral Neutral Q86V59 C97Y Neutral Disease Q8TAP9 M144V Disease Neutral Q96IY1 M254V Neutral Neutral Q495B1 K264E Neutral Neutral Q8IVH4 R359G Disease Disease Q8IVH4 Y207C Disease Disease Q8IVH4 G218E Disease Disease Q8IVH4 R145Q Disease Disease Q8IVH4 L89P Disease Disease Q8IVH4 R359Q Disease Disease Q8IVH4 Q363H Neutral Neutral O15516 H542R Neutral Neutral O15516 L395I Neutral Neutral O15516 S208C Neutral Neutral O15516 E380K Neutral Disease Q99743 S471L Neutral Neutral Q99743 A394T Neutral Neutral P78524 E399D Neutral Neutral P78524 S774G Neutral Neutral P78524 I620T Neutral Disease P78524 K316N Neutral Neutral P78524 S657F Neutral Neutral O95389 Q56H Neutral Neutral O95389 C78R Disease Disease Q32M84 R318Q Neutral Neutral Q32M84 H439P Neutral Neutral Q32M84 G331D Neutral Disease Q32M84 Q472R Neutral Neutral Q4U2R6 M102I Neutral Neutral Q13428 W53R Disease Disease Q15257 S357L Neutral Neutral Q15257 K28R Neutral Disease Q15257 R208Q Neutral Neutral P05111 G227R Neutral Neutral P05111 A257T Neutral Neutral P78312 M192V Neutral Neutral Q6IMN6 M519V Neutral Neutral P04792 R127W Disease Disease P04792 P182L Disease Disease P04792 R136W Disease Disease P04792 T151I Disease Neutral P04792 S135F Disease Disease Q8TEW8 Q295K Neutral Disease Q8TEW8 R192K Neutral Neutral Q8TEW8 L165P Neutral Neutral Q96JF6 I171T Neutral Neutral Q96JF6 V199G Neutral Neutral Q5VY09 Q202R Neutral Neutral Q5VY09 R194G Neutral Neutral Q5VY09 V168I Neutral Neutral Q5VY09 R92H Neutral Neutral Q5VY09 P285S Neutral Neutral Q08828 A940T Neutral Neutral Q08828 P456L Neutral Disease Q9NR81 L335V Neutral Disease Q9NR81 K13R Neutral Neutral Q8TAT2 E206V Neutral Neutral Q4V9L6 I72T Neutral Neutral P01130 R416Q Disease Neutral P01130 R350P Disease Disease P01130 N564H Disease Disease P01130 D224V Disease Neutral P01130 D342N Disease Disease P01130 C116R Disease Disease P01130 R416W Disease Disease P01130 C160Y Disease Disease P01130 R633C Disease Disease P01130 R78C Disease Disease P01130 C173W Disease Disease P01130 R814Q Neutral Neutral P01130 C379Y Disease Disease P01130 A50S Disease Neutral P01130 C368R Disease Disease P01130 C302Y Disease Disease P01130 L414R Disease Disease P01130 P649L Disease Disease P01130 L401V Disease Disease P01130 E714K Disease Neutral P01130 D168N Disease Neutral P01130 D175Y Disease Neutral P01130 C338S Disease Disease P01130 D90N Disease Disease P01130 C95G Disease Disease P01130 F403L Disease Disease P01130 C46S Disease Disease P01130 C231G Disease Disease P01130 C302W Disease Disease P01130 D221Y Disease Neutral P01130 E277K Disease Neutral P01130 D301A Disease Disease P01130 I423T Disease Neutral P01130 D221N Disease Neutral P01130 C276Y Disease Disease P01130 C89Y Disease Disease P01130 C248Y Disease Disease P01130 P608S Disease Disease P98155 E379K Neutral Disease P01130 A391T Neutral Neutral P98155 V791I Neutral Neutral P01130 L568V Disease Disease P01130 C329Y Disease Disease P01130 C197R Disease Disease P01130 D168Y Disease Disease P01130 L432V Disease Neutral P01130 H327Y Disease Disease P01130 C313Y Disease Disease P01130 C261F Disease Disease P98155 L464I Neutral Disease P01130 S56P Disease Disease P98155 I561V Neutral Neutral P01130 D482H Disease Disease P01130 V468I Neutral Neutral P98155 P262H Neutral Neutral P01130 D700E Disease Neutral P01130 V797M Disease Neutral P01130 Q92E Disease Neutral P01130 E288K Disease Neutral P01130 D356Y Disease Disease P01130 A399D Disease Disease P01130 Q366R Disease Disease P98155 V59I Neutral Neutral P01130 C184Y Disease Disease P01130 W483R Disease Disease P01130 G2R Neutral Neutral P98155 R613H Neutral Disease Q15276 E640G Neutral Neutral Q8NCP5 K185E Neutral Neutral Q5VWK5 R381Q Neutral Neutral Q5VWK5 Q3H Neutral Neutral Q5VWK5 P310L Neutral Neutral Q9P2F6 G632D Neutral Disease Q9P2F6 A522T Neutral Neutral Q9Y217 V319I Neutral Neutral P09651 N73S Neutral Neutral Q32P51 N215D Neutral Neutral Q99748 A96S Disease Neutral Q68DC2 V644I Neutral Neutral Q96Q06 A1124T Neutral Neutral P14555 H19Y Neutral Disease P04054 D16A Neutral Neutral P04054 N89K Neutral Disease Q9UNK4 S80G Neutral Neutral P04054 N89T Neutral Disease Q9H900 S344G Neutral Neutral P00749 M214I Neutral Neutral P00749 V15L Neutral Neutral P00749 K231Q Neutral Neutral P00749 P141L Neutral Neutral Q6NSI1 T265K Neutral Neutral Q5C9Z4 V804L Neutral Neutral Q5C9Z4 V812M Neutral Neutral Q5C9Z4 R779H Neutral Neutral Q5C9Z4 H122P Neutral Neutral Q9Y235 I136T Neutral Neutral Q5JY77 A315G Neutral Neutral Q9H7R5 R92H Neutral Neutral Q9H7R5 I582V Neutral Neutral Q9H7R5 A19V Neutral Neutral Q96K76 V163G Neutral Neutral Q8TF65 S61F Neutral Neutral Q8TF65 L206P Neutral Neutral Q92878 K616E Neutral Neutral Q92878 R1038G Neutral Neutral Q92878 V315L Neutral Neutral Q92878 T191I Neutral Neutral Q92878 V127I Neutral Neutral Q92878 I94L Neutral Neutral Q92878 Y964H Neutral Disease Q92878 R224H Neutral Neutral Q92878 V842A Neutral Neutral Q92878 R193W Neutral Neutral Q92878 K973M Neutral Neutral Q92878 V697A Neutral Neutral P12872 V15A Neutral Neutral Q14524 F892I Disease Disease Q14524 V1405L Disease Disease Q14524 R1623Q Disease Disease Q14524 K1500N Neutral Disease Q14524 F1250L Disease Disease Q14524 S1710L Disease Disease Q14524 E1784K Disease Neutral Q14524 R1644H Disease Disease Q14524 Y1795H Disease Neutral Q14524 A1924T Disease Neutral Q14524 S1787N Disease Neutral Q14524 H681P Disease Disease Q14524 T1304M Disease Neutral Q9Y5Y9 S509P Neutral Neutral Q14524 D1839G Disease Disease Q14524 R27H Disease Disease Q9Y5Y9 L1092P Neutral Neutral Q14524 G319S Disease Disease Q14524 I230V Disease Neutral Q14524 N1325S Disease Disease Q14524 G351V Disease Disease Q14524 S524Y Neutral Neutral Q14524 D1114N Disease Neutral Q14524 A997S Disease Neutral Q14524 G1408R Disease Disease Q14524 M369K Disease Disease Q14524 R367H Disease Disease Q14524 E1053K Disease Disease Q14524 L567Q Disease Neutral Q14524 D1275N Disease Disease Q14524 S1382I Disease Neutral Q14524 K1236N Disease Disease Q14524 R1512W Disease Disease Q9Y5Y9 A1073V Neutral Neutral Q14524 R552G Neutral Neutral Q14524 A226V Disease Disease Q14524 G1502S Disease Neutral Q14524 L619F Disease Neutral Q14524 T187I Disease Neutral Q14524 G752R Disease Disease Q14524 L1501V Disease Disease Q14524 F1293S Disease Neutral Q14524 T220I Disease Disease Q14524 D1714G Disease Neutral Q14524 Q1027R Neutral Neutral Q14524 G615E Disease Neutral Q14524 G1319V Disease Disease Q14524 D1790G Disease Disease Q14524 R1193Q Disease Disease Q14524 P1298L Disease Disease Q14524 E1225K Disease Disease Q14524 Y1795C Disease Disease Q14524 A735V Disease Disease Q14524 R367C Disease Disease Q14524 T1620M Disease Disease Q14524 R1826H Disease Disease Q14524 C896S Disease Disease Q14524 G1740R Disease Disease Q14524 A735E Disease Disease Q14524 S910L Disease Neutral Q14524 P1090L Neutral Neutral Q9Y5Y9 V1713M Neutral Disease Q14524 R1232W Disease Disease Q14524 S1103Y Neutral Neutral Q14524 E161K Disease Disease Q14524 D356N Disease Disease Q14524 F1344S Disease Neutral Q14524 R282H Disease Neutral Q14524 V1951L Disease Neutral Q14524 E1240Q Disease Neutral Q14524 T1645M Disease Neutral Q14524 G1406R Disease Disease Q14524 H558R Neutral Neutral Q14524 K126E Disease Disease Q14524 F851L Disease Disease Q14524 V294M Disease Neutral Q14524 R34C Neutral Disease Q14524 G1743E Disease Disease Q14524 R965C Disease Disease Q14524 S941N Disease Neutral Q14524 G1262S Disease Disease Q14524 R1623L Disease Disease Q9UPX6 I832V Neutral Neutral Q9UPX6 V320F Neutral Neutral Q96DV4 D371H Neutral Disease Q8IUA0 N137S Neutral Neutral Q8IUA0 M96T Neutral Neutral O15027 R861C Neutral Neutral P30793 H144P Disease Disease P30793 D134V Disease Disease P30793 R184H Disease Disease P30793 M213V Disease Disease P30793 R88W Disease Disease P30793 D115N Disease Neutral P30793 R88P Disease Disease P30793 C141R Disease Disease P30793 G83A Disease Disease P30793 F234S Disease Disease P30793 G201E Disease Disease P30793 V191I Disease Neutral P30793 H153P Disease Disease P30793 R178S Disease Disease P30793 A74V Disease Disease P30793 C141W Disease Disease P30793 G90V Disease Disease P30793 R249S Disease Disease P30793 P23L Disease Neutral P30793 R241W Disease Disease P30793 S176T Disease Disease P30793 G203R Disease Disease P30793 K224R Disease Neutral P30793 T186K Disease Disease P30793 P199L Disease Disease P30793 L71Q Disease Disease P30793 M211I Disease Disease P30793 M102R Disease Disease P30793 I135K Disease Disease P30793 M211V Disease Disease P30793 M102K Disease Disease P30793 L79P Disease Disease P30793 Q180R Disease Disease P30793 L163R Disease Disease P80365 R213C Disease Disease P80365 R337C Disease Disease P37059 A121T Neutral Neutral P80365 A328V Disease Disease P80365 R279C Disease Neutral P80365 R208C Disease Disease P80365 L250R Disease Disease P80365 R186C Disease Disease P80365 A237V Disease Disease P80365 R208H Disease Disease P80365 D244N Disease Disease P80365 L179R Disease Disease P80365 S180F Disease Disease Q92985 Q412R Neutral Neutral Q92985 K179E Neutral Neutral Q8NBL3 L107V Neutral Neutral Q76MJ5 R184C Neutral Neutral Q76MJ5 H857Y Neutral Disease Q76MJ5 R536Q Neutral Disease Q76MJ5 R118C Neutral Disease Q76MJ5 L503F Neutral Neutral Q76MJ5 T486S Neutral Neutral Q76MJ5 A318T Neutral Neutral Q76MJ5 Q271R Neutral Neutral Q76MJ5 L410F Neutral Neutral Q76MJ5 V69I Neutral Neutral Q14774 P356L Neutral Neutral Q14774 S116P Neutral Neutral Q96KB5 M241L Neutral Neutral Q96KB5 N107S Neutral Neutral Q96PX1 P80H Neutral Disease Q96PX1 G208R Neutral Disease P60022 V38I Neutral Neutral P60022 C67S Neutral Neutral P60022 A48V Neutral Neutral Q02818 R399Q Neutral Neutral O96018 K276T Neutral Disease O96018 I527F Neutral Disease O75140 S491T Neutral Neutral Q9UBV7 A186D Disease Disease Q9UBV7 L206P Disease Disease Q9BQI5 E112Q Neutral Neutral Q9BQI5 P161Q Neutral Neutral Q9BQI5 K131R Neutral Neutral Q9BQI5 K575E Neutral Disease Q5T8P6 V718D Neutral Disease Q9NP94 H154Y Neutral Neutral Q9NP94 G129E Neutral Neutral Q9NP94 M80V Neutral Neutral Q9BRY0 F100L Neutral Neutral Q9BRY0 P257L Neutral Neutral Q96A99 A317S Neutral Neutral Q96A99 R234Q Neutral Neutral Q96A99 R220G Neutral Neutral Q96A99 R281K Neutral Neutral Q96A99 L333M Neutral Neutral Q96A99 R92W Neutral Neutral Q8IVF2 G5564R Neutral Neutral Q8IVF2 V2616A Neutral Disease Q8IVF2 L2430V Neutral Neutral Q8IVF2 S2115R Neutral Disease Q8IVF2 L5028M Neutral Neutral Q8IVF2 V1266M Neutral Disease Q8IVF2 D2429E Neutral Neutral Q8IVF2 L1470V Neutral Neutral Q13395 L221P Neutral Neutral Q13395 H864P Neutral Neutral Q13395 T1038I Neutral Neutral Q13395 I1461V Neutral Neutral Q13395 S678G Neutral Neutral Q13395 A425T Neutral Neutral Q13395 I1359V Neutral Neutral Q13395 F997L Neutral Neutral Q13395 N743S Neutral Neutral Q9Y2I7 K1103R Disease Neutral Q9NXR8 D20G Disease Neutral Q9H967 A153S Neutral Neutral Q9H967 S614G Neutral Neutral P41217 S11C Neutral Neutral P41217 P46T Neutral Neutral O75161 T946A Disease Neutral O75161 R1192W Disease Neutral O75161 R961H Disease Neutral O75161 Q1287E Disease Neutral O75161 D3Y Disease Neutral O75161 R342C Disease Neutral O75161 T29M Neutral Neutral O75161 P776R Disease Neutral O75161 L939Q Neutral Neutral O75161 Q766R Disease Neutral O75161 A544G Neutral Neutral O75161 T1225M Disease Neutral O75161 A654G Disease Neutral O75161 T627M Disease Neutral O75161 E618K Neutral Neutral O75161 G754R Disease Disease O75161 R1284C Disease Neutral O75161 R848W Neutral Neutral O75161 V765I Neutral Neutral O75161 H782Q Disease Neutral O75161 R740H Neutral Neutral O75161 R469W Disease Neutral O75161 F91L Disease Disease O75161 F991S Disease Disease O75161 R959Q Neutral Neutral O75161 R735W Disease Neutral O75161 A1098T Disease Neutral Q9Y3X0 E215D Neutral Neutral Q9Y3X0 A456V Neutral Neutral Q76NI1 L717P Neutral Neutral Q76NI1 G581S Neutral Neutral Q76NI1 E436G Neutral Neutral Q96RU3 S490N Neutral Neutral P49792 V548L Neutral Neutral P49792 P1870L Neutral Neutral P49792 R784K Neutral Neutral P49792 P1892A Neutral Neutral P49792 E580K Neutral Neutral P49792 C581Y Neutral Neutral Q6ZV29 L993M Neutral Neutral Q6ZV29 V824M Neutral Disease Q6ZV29 E368D Neutral Neutral Q6ZV29 R323Q Neutral Neutral Q6ZV29 Q364E Neutral Neutral Q8IY17 K1024R Neutral Neutral Q8IY17 A403P Neutral Neutral Q6ZV29 P908L Neutral Neutral Q6ZV29 V803A Neutral Neutral Q96P15 M148T Neutral Neutral Q96P63 N289T Neutral Neutral P01008 Y17S Disease Neutral P36952 I319V Neutral Neutral P29508 G351A Neutral Neutral P01008 C32R Disease Disease P01008 A459D Disease Disease P01008 L178H Disease Disease P01008 Y198C Disease Disease P05154 G217R Neutral Disease P01008 R79S Disease Disease P01008 F261L Disease Disease P01008 K146E Disease Disease P01008 L302P Disease Disease P01008 N437K Disease Disease P35237 G153S Neutral Disease P01008 S214Y Disease Disease P01008 F90L Disease Disease P01008 N219K Disease Disease P01008 S397P Disease Disease P01008 L131F Disease Disease P01008 R391Q Neutral Disease P01011 A9T Neutral Neutral P01008 I39N Disease Disease P05543 S43T Disease Disease P01008 Q133K Disease Disease P05120 R229H Neutral Neutral P48595 R246C Neutral Disease P05543 L247P Disease Disease P01008 L131V Disease Disease P01008 P439T Disease Disease P01008 Y95C Disease Disease P08185 D389N Disease Disease P01008 R56C Disease Disease P01008 T147A Neutral Neutral P01008 Y95S Disease Disease P48595 I41M Neutral Neutral P29508 T357A Neutral Neutral P05154 G94V Neutral Neutral P01008 P73L Disease Neutral P01008 R425P Disease Disease P01008 P461L Disease Disease P01008 L23P Disease Disease P05543 I116N Disease Disease P01008 H152Y Disease Disease P01009 R125H Neutral Disease P01008 I316N Disease Disease P01008 P112T Disease Disease P01008 M121K Disease Disease P01008 R89C Disease Disease P01008 A436T Disease Neutral P08185 S246A Neutral Neutral P05121 T255N Neutral Neutral P05543 L303F Neutral Disease P05154 K105E Neutral Neutral P05154 P121A Neutral Neutral P01011 P252A Disease Neutral P01008 Y190C Neutral Disease P05120 S413C Neutral Disease Q86U17 T406S Neutral Neutral P01008 R457T Disease Disease P01009 V237A Neutral Neutral Q99574 S49P Disease Disease P05121 V17I Neutral Neutral P05543 H351Y Disease Disease P01008 S223P Disease Disease P01008 R79H Disease Disease P05120 N120D Neutral Neutral P01009 G139S Neutral Disease P01008 P439L Disease Disease P01008 A416P Disease Disease P01008 S381P Disease Disease P01009 A360T Neutral Neutral P05154 L115P Neutral Disease P01008 I251T Disease Disease P01008 R425H Disease Disease P05120 N404K Neutral Disease P01008 R438M Disease Disease P35237 M90V Neutral Neutral P01009 E288V Neutral Disease Q96P63 K227E Neutral Neutral Q99574 S52R Disease Disease P01008 S323P Disease Disease P01011 D407G Neutral Disease P01008 E269K Disease Disease P01008 E334K Disease Neutral P01008 L98P Disease Disease P05121 A15T Neutral Neutral P01008 L158P Disease Disease P01008 C462F Disease Disease P01008 R438G Disease Neutral P01008 Q150P Disease Disease P01008 I453T Disease Disease Q96P15 I181T Neutral Neutral P01008 G424D Disease Disease Q9UIV8 G293S Neutral Neutral P01008 M283I Disease Disease P01008 S148P Disease Disease P01008 G456R Disease Disease P01008 N167T Neutral Neutral P01008 L441P Disease Disease O75830 E148G Neutral Neutral O75635 R266Q Neutral Neutral P01008 R79C Disease Disease P48595 I99T Neutral Disease P01008 A414T Disease Disease P01008 M283V Disease Disease P01008 N219D Disease Disease P01008 T243I Disease Disease P01008 W257R Disease Disease P01011 L78P Disease Disease P08185 L115H Disease Disease P01008 F434C Disease Disease P01008 A416S Disease Disease P01008 D398H Disease Neutral P05154 A55V Neutral Neutral P05543 A133P Disease Disease P05543 P383L Disease Disease P01008 F179L Disease Disease P01008 F434L Disease Disease P01008 S426L Disease Disease P05121 R209H Neutral Neutral P01008 R425C Disease Disease P05121 H25P Neutral Disease P01008 A419V Disease Disease P01008 S214F Disease Disease P05154 S44G Neutral Neutral P01008 R161Q Disease Disease P48595 P140S Neutral Neutral P01008 C160Y Disease Neutral P01009 E400D Neutral Neutral P01008 S412R Disease Disease P05154 N64S Neutral Disease P01011 K267R Neutral Disease P01008 Y198H Disease Disease P01011 A167G Neutral Neutral P01008 F434S Disease Disease P01008 V30E Neutral Disease P01008 C127R Disease Neutral O77932 A332V Neutral Neutral O77932 S28T Neutral Neutral O77932 D63E Neutral Disease O77932 H261Q Neutral Neutral Q8NCW6 D197Y Neutral Disease Q8NCW6 P151S Neutral Disease Q0ZLH3 T54I Disease Disease Q0ZLH3 R183W Disease Neutral Q8IZJ1 A516T Neutral Neutral O95185 G37V Neutral Neutral O95185 T721M Neutral Neutral Q15782 V184I Neutral Neutral P36222 I311T Neutral Disease P36222 R145G Neutral Neutral Q63HM2 D182Y Neutral Neutral Q63HM2 G371S Neutral Neutral Q63HM2 Q141H Neutral Neutral P21439 R590Q Neutral Disease P21439 E528D Neutral Disease O95342 E297G Disease Disease O95342 R1050C Disease Disease O95342 M677V Neutral Neutral O95342 G1004D Disease Disease O95342 R432T Disease Disease O95342 T923P Disease Disease O95342 G238V Disease Neutral O95342 R1153C Disease Disease O95342 V284L Disease Disease P21439 I263V Neutral Neutral P21439 T175A Disease Neutral P21439 A546D Disease Disease O95342 R616G Neutral Disease O95342 E186G Disease Disease O95342 G982R Disease Neutral O95342 R1128H Disease Disease P21439 S320F Disease Neutral P21439 P1168S Disease Disease O95342 K461E Disease Disease O95342 V284A Neutral Disease O95342 R299K Neutral Disease O95342 D482G Disease Disease O95342 A926P Disease Disease P21439 L238V Neutral Neutral O95342 A865V Neutral Neutral P21439 T651N Neutral Neutral P21439 R652G Neutral Disease P21439 R788Q Neutral Disease O95342 V444A Neutral Disease O95342 T619A Neutral Disease O95342 R958Q Neutral Disease O95342 C336S Disease Neutral O95342 A570T Disease Disease O95342 R1268Q Disease Disease O95342 I206V Neutral Neutral O95342 R698H Neutral Neutral O95342 E1186K Neutral Disease Q6ZTK2 Q183H Neutral Neutral Q6ZTK2 T368A Neutral Neutral Q6ZTK2 W419R Neutral Neutral Q6ZTK2 Q100R Neutral Neutral Q6ZTK2 E330Q Neutral Neutral Q6ZTK2 V345I Neutral Neutral Q6ZTK2 V275A Neutral Neutral Q86TE4 E308Q Neutral Neutral Q9UHD1 A329D Neutral Neutral O15439 G487E Neutral Disease O15439 G187W Neutral Disease O15439 T1142M Neutral Neutral O15439 I625M Neutral Disease O15439 P78A Neutral Neutral O15439 K304N Neutral Neutral O15439 Q1314R Neutral Neutral O15439 E757K Neutral Disease O15439 M184T Neutral Neutral O15439 P667L Neutral Neutral O15439 P403L Neutral Neutral O15439 V860M Neutral Neutral O15439 K498E Neutral Disease O15439 M744V Neutral Neutral O15439 V900L Neutral Neutral Q16891 P124S Neutral Neutral O00300 K3N Neutral Neutral O00300 V104M Neutral Disease A1A5D9 R273Q Neutral Neutral Q17RF5 R109H Neutral Neutral Q17RF5 P30L Neutral Neutral P47804 S241F Neutral Neutral P47804 H152N Neutral Disease P47804 S66R Disease Disease P47804 V132L Neutral Neutral P47804 A234T Neutral Neutral O95361 G561V Neutral Neutral O95361 E121D Neutral Neutral Q01629 T41M Neutral Neutral P01275 A115V Neutral Disease Q6ZMZ3 T668M Neutral Neutral Q6ZMZ3 I946V Neutral Neutral Q6ZMZ3 R864H Neutral Neutral Q6ZMZ3 A923V Neutral Neutral P57081 K71N Neutral Neutral P57081 R390Q Neutral Neutral P57081 P266S Neutral Neutral Q99519 L270P Disease Disease Q99519 G227R Disease Disease Q99519 R225P Disease Disease Q99519 L363P Disease Disease Q99519 V217M Disease Neutral Q99519 A298V Disease Neutral Q99519 L231H Disease Neutral Q99519 F260Y Disease Neutral Q99519 P80L Disease Disease Q99519 P316S Disease Disease Q99519 P335Q Disease Disease Q99519 V54M Disease Neutral Q99519 L91R Disease Disease Q99519 W240R Disease Disease Q99519 L270F Disease Disease Q99519 Y370C Disease Disease Q99519 G68V Disease Disease Q99519 G328S Disease Neutral Q99519 G219A Disease Neutral Q99519 R341G Disease Disease Q99519 S182G Disease Disease Q99519 R294S Disease Neutral Q99519 G243R Disease Disease O00541 T264S Neutral Neutral Q92956 V241I Neutral Neutral Q92956 K17R Neutral Neutral Q92956 A117T Neutral Neutral Q92956 G174E Neutral Neutral Q99965 G10W Neutral Neutral Q9UI46 A60V Neutral Neutral Q9UI46 A8S Neutral Neutral Q9UI46 G515S Disease Disease Q9UI46 V487G Neutral Neutral Q9UI46 V335I Neutral Neutral Q9UI46 Q326H Neutral Neutral Q86YL7 G147A Neutral Neutral Q86YL7 A105G Neutral Neutral Q9H9A6 Q53P Neutral Disease Q9H9A6 I500V Neutral Disease P49441 T228A Neutral Neutral Q9HCU8 R39P Neutral Neutral P14406 E40D Neutral Neutral P55317 A72G Neutral Neutral P55317 A83T Neutral Neutral P55317 R186Q Neutral Neutral P55317 S449N Neutral Neutral Q5T0W9 N410S Neutral Neutral Q5T0W9 T907N Neutral Neutral Q5T0W9 K640T Neutral Neutral Q5T0W9 S435R Neutral Neutral Q96PN6 T234M Neutral Neutral Q96PN6 V697I Neutral Neutral Q9NVR7 K149R Neutral Neutral Q14094 V207I Neutral Neutral Q8N2H3 M461T Neutral Neutral Q8N2H3 P428S Neutral Neutral Q8N2H3 A533T Neutral Neutral Q8NBF6 C257S Neutral Neutral Q92934 A107S Neutral Neutral Q92935 H379N Neutral Neutral O60268 R100H Neutral Neutral Q7Z2Z1 R628C Neutral Neutral Q63HK3 E615D Neutral Neutral Q63HK3 L253F Neutral Neutral Q6ZN28 E728A Neutral Neutral Q6ZN28 S515L Neutral Neutral Q6ZN28 P50L Neutral Neutral Q6ZN28 R804T Neutral Disease Q6ZN28 L31V Neutral Neutral Q5VYX0 E37D Neutral Neutral Q6ZTQ3 S163P Neutral Neutral Q9H2L5 R88G Neutral Neutral Q6ZTQ3 A306G Neutral Neutral Q9H2L5 H10Y Neutral Neutral A6PVS8 H156Y Neutral Neutral A6PVS8 M129I Neutral Neutral A6PVS8 F35C Neutral Neutral Q96SD1 G135E Disease Disease Q96SD1 H35D Disease Disease Q96SD1 G118V Disease Disease O43464 G399S Disease Disease O43464 A141S Neutral Neutral P15259 E89A Disease Disease Q8N0Y7 R40C Neutral Disease Q8N0Y7 R90Q Neutral Disease Q8N0Y7 I175T Neutral Disease P15259 R90W Disease Disease P15259 G97D Disease Disease P14672 A358V Neutral Neutral P14672 I385T Neutral Neutral P14672 T78S Neutral Neutral P14672 V383I Disease Neutral P26572 P435L Neutral Neutral P26572 R223Q Neutral Neutral Q9UJZ1 L129P Neutral Disease Q96DZ5 D175V Neutral Disease Q4G0Z9 L317V Neutral Neutral Q4G0Z9 S578A Neutral Neutral Q4G0Z9 M132K Neutral Disease Q8TC84 R46S Neutral Neutral Q8TC84 L329V Neutral Neutral Q8TAY7 H53R Neutral Neutral Q9GZT8 T324I Neutral Neutral Q99697 R115H Disease Disease Q99697 R108H Disease Neutral Q99697 R89W Disease Disease Q99697 L100Q Disease Disease Q99697 T114P Disease Disease Q99697 R137P Disease Disease Q99697 V129L Disease Disease Q99698 H123R Neutral Neutral Q99698 L192V Neutral Neutral Q99698 R1563H Disease Neutral Q99698 V1999D Disease Disease P62753 K221R Neutral Neutral P15559 R139W Neutral Disease P15559 P187S Neutral Neutral P34949 I140T Disease Neutral P34949 I398T Disease Disease P34949 Y255C Disease Disease P34949 R219Q Disease Disease P34949 S102L Disease Disease P34949 Y129C Disease Disease P34949 D131N Disease Disease P34949 R295H Disease Disease P34949 M51T Disease Disease P34949 R418H Disease Disease P34949 G250S Disease Disease P34949 M138T Disease Disease P34949 R152Q Disease Disease Q8ND04 P280L Neutral Neutral P30086 S9N Neutral Neutral Q9BXT6 I454L Neutral Neutral Q9BXT6 R182C Neutral Disease Q9BXT6 A1179E Neutral Neutral Q9BXT6 S683G Neutral Neutral Q9BXT6 M57L Neutral Neutral Q9BXT6 V650I Neutral Neutral Q9BXT6 Q820R Neutral Neutral Q7Z6B0 M261V Neutral Neutral Q7Z6B0 M314V Neutral Neutral P11498 V145A Disease Neutral P11498 R451C Disease Neutral P11498 M743I Disease Disease P11498 A610T Disease Disease Q9NZJ5 P715L Neutral Neutral Q9NZJ5 R587Q Disease Disease Q9NZJ5 S135C Neutral Neutral Q9NZJ5 R165Q Neutral Neutral Q9NZJ5 S703A Neutral Neutral Q9NZJ5 D565V Neutral Neutral Q16836 A40T Disease Disease Q16836 P86L Neutral Disease Q16836 P258L Disease Disease Q16836 D57E Disease Disease A2RUB1 M145L Neutral Neutral A2RUB1 N154T Neutral Neutral P11684 R56G Neutral Neutral P11684 T68A Neutral Neutral Q96B36 A47P Neutral Neutral Q9Y6R7 G1616V Neutral Neutral Q9Y6R7 H3920Q Neutral Neutral Q9Y6R7 S4465G Neutral Neutral Q9Y6R7 A2793V Neutral Neutral Q9Y6R7 N2089D Neutral Neutral Q9Y6R7 M1617V Neutral Neutral Q9Y6R7 E2646D Neutral Neutral Q9Y6R7 E2647K Neutral Neutral Q9Y6R7 G4095D Neutral Disease Q9Y6R7 V1340L Neutral Neutral Q9Y6R7 G3264S Neutral Disease Q9Y6R7 D4906H Neutral Disease Q9Y6R7 V4015A Neutral Neutral Q9Y6R7 V2814A Neutral Neutral Q9NWF4 V296M Neutral Neutral Q9NWF4 A271V Neutral Neutral Q9NWF4 R70Q Neutral Neutral P18074 R658H Disease Disease P18074 D312N Neutral Neutral P18074 D681N Disease Disease P18074 L461V Disease Disease P18074 G602D Disease Disease P18074 R666W Disease Disease P18074 R616C Neutral Disease P18074 D673G Disease Disease P18074 R683Q Disease Disease P18074 R487G Disease Disease P18074 K751Q Neutral Neutral P18074 C663R Disease Disease P18074 G713R Disease Disease P18074 R683W Disease Disease P18074 I199M Neutral Neutral P18074 R601L Disease Disease P18074 T76A Disease Disease P18074 D234N Disease Disease P18074 H201Y Neutral Disease P18074 G47R Disease Disease P18074 R658C Disease Disease P18074 A594P Disease Disease P18074 R658G Disease Disease P18074 L485P Disease Disease P18074 C259Y Disease Neutral P18074 S541R Disease Disease P18074 R722W Disease Disease P18074 A725P Disease Disease P18074 R616W Disease Disease P18074 Y542C Disease Disease P18074 R592P Disease Disease P18074 R616P Disease Disease P18074 R112H Disease Disease P18074 R511Q Disease Disease P18074 R601W Disease Disease P16157 V463I Disease Neutral Q9ULJ1 K350R Neutral Neutral Q9ULJ1 R177H Neutral Neutral Q2T9K0 H24N Neutral Disease Q9Y2Z4 G191V Neutral Disease Q6W5P4 I315T Neutral Neutral Q6W5P4 R122Q Neutral Disease Q6W5P4 T212I Neutral Neutral Q6W5P4 N107I Neutral Neutral Q6W5P4 Q344R Neutral Neutral Q6W5P4 C197F Neutral Disease Q6W5P4 S143G Neutral Neutral Q6W5P4 S241R Neutral Disease Q9Y4P1 Q354L Neutral Neutral P35916 G857R Disease Disease P35916 P1137S Disease Disease P35916 H1035R Disease Disease P35916 L1044P Disease Disease P35916 R1041P Disease Disease P35916 P954S Disease Disease P35916 P1114L Disease Disease Q9BSJ2 A111T Neutral Neutral O94759 I1368M Neutral Neutral O94759 E1359K Neutral Neutral O94759 N52K Neutral Neutral O94759 D543E Neutral Neutral O94759 S1201G Neutral Neutral O94759 V166I Neutral Neutral O94759 T1347M Neutral Disease O94759 V385M Neutral Neutral O94759 D780E Neutral Neutral O94759 A1438S Neutral Disease O94759 Q1189R Neutral Neutral O94759 N1249S Neutral Neutral O94759 R1199W Neutral Disease P51610 S1164P Neutral Neutral Q7Z402 R59W Neutral Neutral Q7Z402 T635I Neutral Neutral Q7Z402 G254E Neutral Neutral Q7Z404 E17G Neutral Neutral Q7Z404 Q683E Neutral Neutral Q9ULH0 R1307H Neutral Neutral Q9ULH0 Q1608H Neutral Neutral Q9HB31 S212L Neutral Neutral Q86UT6 R125L Neutral Disease Q86UT6 A843S Neutral Neutral Q86UT6 P63S Neutral Neutral Q86UT6 A793E Neutral Disease Q9H6L5 Q379E Neutral Neutral Q8WTS1 E260K Disease Disease Q8WTS1 I72T Neutral Neutral Q8WTS1 E7K Disease Neutral Q8WTS1 Q130P Disease Disease P19099 N222T Neutral Neutral P15538 T318M Disease Disease P19099 A29T Neutral Neutral P15538 A348T Neutral Neutral P15538 P42S Disease Disease P19099 V386A Disease Neutral P19099 L461P Disease Disease P05108 A189V Disease Neutral P19099 T185I Disease Disease P15538 C494F Neutral Disease P19099 G435S Neutral Neutral P05108 R353W Disease Disease P19099 K173R Neutral Neutral P19099 T498A Disease Neutral P19099 I339T Neutral Neutral P15538 R374Q Disease Disease P19099 R30Q Neutral Neutral P15538 C10Y Neutral Neutral P19099 F487V Neutral Disease P19099 N281S Neutral Neutral P15538 V386A Neutral Neutral P15538 L293V Neutral Neutral P15538 R448H Disease Disease P19099 V403E Neutral Disease P15538 F257L Neutral Neutral P15538 T319M Disease Disease P15538 N133H Disease Neutral P19099 R181W Disease Disease P15538 M160I Neutral Disease P15538 D63H Neutral Neutral P19099 E198D Disease Neutral P19099 I248T Neutral Neutral P15538 Y439H Neutral Disease P19099 E383V Neutral Neutral P15538 Q43R Neutral Neutral P05108 E314K Neutral Disease P15538 S281N Neutral Neutral P15538 K173R Neutral Neutral Q15329 G18A Neutral Neutral P29536 T267M Neutral Neutral Q7Z5W3 S288R Neutral Neutral Q08830 T15I Neutral Neutral Q08830 I72V Neutral Neutral Q08830 P105L Neutral Disease Q08830 Y140F Neutral Neutral Q08830 Y111H Neutral Neutral Q08830 T121S Neutral Disease Q8WWN9 S194P Neutral Neutral P16671 I413L Disease Neutral P16671 V154F Neutral Disease P16671 P90S Disease Disease P16671 S127L Neutral Disease P16671 F254L Disease Disease P49840 L461F Neutral Neutral O95391 T229M Neutral Neutral O95391 I111V Neutral Neutral Q9H4K1 R262Q Neutral Neutral Q9H4K1 R180C Neutral Neutral Q9H4K1 F195L Neutral Neutral Q9P2E3 Q924H Neutral Neutral Q9P2E3 T1351I Neutral Neutral Q9P2E3 M1259I Neutral Neutral Q9P2E3 L864V Neutral Neutral Q9P2E3 T910A Neutral Neutral Q9H6Y7 N121K Neutral Neutral P18545 P27H Neutral Neutral O95476 A12T Neutral Neutral P35575 G270V Disease Disease P35575 L211P Disease Disease P35575 V338F Disease Disease P35575 G81R Disease Disease P35575 G184E Disease Disease P35575 Q54P Disease Disease P35575 R83C Disease Disease P35575 I341N Disease Disease P35575 W77R Disease Disease P35575 W156L Disease Disease P35575 G266V Disease Disease P35575 T108I Disease Neutral P35575 A124T Disease Neutral P35575 D38V Disease Disease P35575 R295C Disease Disease P35575 E110K Disease Disease P35575 G188D Disease Disease P35575 R83H Disease Disease P35575 V166G Disease Disease P35575 G222R Disease Disease P35575 G188R Disease Disease P35575 R83I Disease Disease P35575 Q20R Disease Disease Q13093 Q281R Disease Neutral Q13093 I198T Neutral Neutral Q13093 R92H Neutral Neutral Q13093 V279F Disease Neutral Q13093 V379A Neutral Neutral P98088 L4897P Neutral Disease P31277 G245D Neutral Neutral O43248 P130S Neutral Neutral O43248 A222V Neutral Neutral P50539 E152A Disease Neutral P0C5J1 R285S Neutral Disease P0C5J1 D43Y Neutral Neutral Q96G04 S123C Neutral Neutral Q9HAU5 N496S Neutral Neutral P12821 R379Q Neutral Neutral P12821 I1018T Neutral Disease P12821 R561W Neutral Disease P12821 A261S Neutral Neutral P12821 T1187M Neutral Disease P12821 A183T Neutral Neutral P12821 G354R Neutral Disease P12821 V524A Neutral Neutral P12821 R1279Q Neutral Neutral P12821 Y244C Neutral Disease P12821 Q1296P Neutral Neutral P12821 F1051V Neutral Disease P12821 T916M Neutral Disease P12821 R1286S Neutral Neutral P12821 A154T Neutral Disease P12821 M828T Neutral Neutral P12821 P351L Neutral Disease P12821 D592G Neutral Neutral O14828 D242V Neutral Neutral O14828 R38L Neutral Neutral O14828 A235V Neutral Neutral O14828 N239I Neutral Neutral P25067 G357R Disease Disease P25067 Q455K Disease Neutral P25067 G3R Neutral Neutral P25067 T645I Neutral Neutral P25067 P575L Disease Disease P25067 R304Q Disease Neutral P25067 R155Q Disease Neutral P25067 T502M Neutral Neutral P25067 R434H Disease Neutral Q7Z5S9 D157G Neutral Neutral Q8WVM8 K63R Neutral Neutral Q9H790 G172V Neutral Neutral Q9H790 D115N Neutral Neutral Q8IVM7 R154Q Neutral Neutral P01137 R218C Disease Disease P01137 L10P Neutral Neutral P01137 R25P Neutral Disease P61812 R91H Neutral Neutral P01137 C225R Disease Disease P01137 Y81H Disease Disease P01137 R218H Disease Neutral P01137 T263I Neutral Neutral P01137 H222D Disease Disease P10600 T60M Neutral Neutral P61812 V207L Neutral Disease Q8WXD0 T222P Disease Neutral Q8WXD0 I604V Neutral Neutral Q9HB96 G340R Neutral Neutral Q9HB96 A502T Neutral Neutral Q9HB96 R343Q Neutral Neutral Q9HB96 P184Q Disease Neutral Q9HB96 R89L Neutral Neutral Q9HB96 S204L Neutral Neutral O14617 G541R Neutral Neutral O14617 I1072V Neutral Neutral P55072 R191Q Disease Neutral P55072 R155H Disease Neutral P55072 R95G Disease Neutral P55072 R155P Disease Disease P55072 R155C Disease Disease P55072 A232E Disease Disease P55072 R159H Disease Neutral Q9Y6N3 I104T Neutral Disease Q9Y6N3 Y84T Neutral Disease Q96QZ0 G95R Neutral Neutral Q96QZ0 T208A Neutral Neutral Q8N1N5 C89Y Neutral Disease Q8N1N5 H95P Neutral Disease Q96T88 T642M Neutral Neutral Q96T88 A638T Neutral Neutral Q96T88 L713F Neutral Neutral Q96T88 E379K Neutral Neutral Q96T88 D240H Neutral Neutral Q6PJP8 G582W Neutral Neutral Q6PJP8 P287L Neutral Neutral Q6PJP8 G71D Neutral Neutral Q6PJP8 H317D Neutral Neutral Q6PJP8 E59D Neutral Neutral Q6PJP8 I859F Neutral Neutral Q6PJP8 K58E Neutral Neutral Q9P035 E56K Neutral Disease Q9P035 M269L Neutral Neutral P08574 V76M Neutral Neutral P08574 L89V Neutral Neutral Q8IYA8 D430E Neutral Neutral O43734 R83W Neutral Neutral O43734 Q332H Neutral Neutral Q96GR2 E194V Neutral Neutral Q96GR2 A673V Neutral Neutral Q96GR2 V633M Neutral Neutral Q5T0N1 W849L Neutral Neutral Q5T0N1 N944D Neutral Neutral Q9UBH0 N47S Neutral Neutral Q70EL2 S778N Neutral Neutral Q9Y5T5 Q141H Neutral Neutral Q70EL2 K67E Neutral Neutral O75871 K69R Neutral Disease P40198 S7P Neutral Neutral O75871 H29D Neutral Disease Q9H5Q4 P156L Neutral Disease Q9H5Q4 H264Y Neutral Disease Q9BU64 Q34R Neutral Neutral Q7Z6M4 D378E Neutral Neutral Q7Z6M4 D347E Neutral Neutral Q7Z6M4 L339V Neutral Neutral Q7Z6M4 M189T Neutral Neutral Q7Z6M4 T45A Neutral Neutral P26441 N49S Neutral Neutral P26441 H182R Neutral Neutral P14061 S313G Neutral Neutral P14061 A238V Neutral Disease Q9Y2N7 F463L Neutral Disease Q9Y2N7 Q343R Neutral Neutral P02774 D432E Neutral Neutral P02774 R445C Neutral Neutral P02774 K436T Neutral Neutral P02774 R445H Neutral Neutral Q15154 G871V Neutral Neutral Q15154 R1250H Neutral Neutral Q15154 A691S Neutral Neutral Q15154 A176D Neutral Disease Q15154 T1542I Neutral Neutral Q15154 V597M Neutral Neutral Q15154 S159N Neutral Neutral Q9Y6B7 L480S Neutral Neutral A4D1S0 T152K Neutral Neutral A4D1S0 G339A Neutral Neutral Q9HC77 D63H Neutral Neutral Q9HC77 P55A Neutral Neutral Q9HC77 E151G Neutral Neutral Q9HC77 M21V Neutral Neutral Q9HC77 S879A Neutral Neutral Q9HC77 P85T Neutral Neutral Q9HC77 E1235V Disease Disease P17931 H64P Neutral Neutral P17931 P98T Neutral Disease Q99884 L345V Neutral Disease O75388 F327L Neutral Neutral Q96PF2 T280M Neutral Neutral Q96PF2 Y197C Neutral Disease Q96PF2 M61V Neutral Neutral Q9BXA7 R237C Neutral Neutral Q9BXA7 G288W Neutral Neutral Q9BXA7 H83Y Neutral Disease Q9BXA7 V233L Neutral Neutral Q9BXA7 A50T Neutral Neutral Q9BXA7 G293E Neutral Neutral Q96PF2 K27R Neutral Disease Q8N461 L429P Neutral Disease Q8N465 D375Y Disease Disease Q8N465 R15G Neutral Neutral Q8N465 V444A Disease Disease Q8N465 N439D Disease Disease Q8N465 G436V Neutral Disease Q8N465 I147S Disease Neutral Q9BSE2 V147M Neutral Neutral Q7L2Z9 G63R Neutral Neutral Q7L2Z9 D266G Neutral Neutral P56545 E47D Neutral Neutral Q9UQ10 S66N Neutral Neutral Q9UQ10 G282R Neutral Disease Q9UQ10 V247A Neutral Neutral Q9UQ10 A2P Neutral Disease Q9UQ10 V200M Neutral Neutral Q9Y616 H57R Neutral Neutral Q9Y616 I270V Neutral Neutral Q9Y616 M391T Neutral Neutral Q9Y616 I171V Neutral Neutral Q9Y616 G269S Neutral Disease Q9Y616 D482N Neutral Neutral Q9Y616 S288L Neutral Neutral Q9Y616 R384Q Neutral Neutral Q9Y616 G84S Neutral Neutral Q9Y616 V147I Neutral Neutral Q969J5 E190K Neutral Neutral Q969J5 L16P Neutral Disease Q4G0N8 T424A Neutral Neutral Q4G0N8 I348M Neutral Neutral Q4G0N8 I286V Neutral Neutral Q4G0N8 Q732K Neutral Neutral Q4G0N8 T705I Neutral Neutral Q4G0N8 S768I Neutral Neutral Q4G0N8 I158V Neutral Neutral Q01362 E237G Neutral Neutral Q9H1R3 A87V Disease Neutral Q9H1R3 A95E Disease Neutral Q9H992 G379S Neutral Neutral Q9H992 T193I Neutral Neutral Q9H992 T100S Neutral Neutral Q3KRA6 V46I Neutral Neutral Q3KRA6 R116K Neutral Neutral Q6TFL3 I17N Neutral Neutral Q6TFL3 S121T Neutral Neutral Q6TFL3 K1069R Neutral Neutral Q6TFL3 N495I Neutral Neutral Q9HC58 G271S Neutral Neutral Q9HC58 V55I Neutral Neutral Q9HC58 V168I Neutral Neutral Q9HC58 L49P Neutral Neutral A6NLJ0 F276V Neutral Disease A6NLJ0 D346E Neutral Neutral Q9GZS1 V418M Neutral Neutral Q9GZS1 R445K Neutral Neutral Q9GZS1 D254H Neutral Neutral P15514 D80V Neutral Neutral P15514 Y81C Neutral Neutral O00213 N396S Neutral Disease O00213 M327V Neutral Neutral Q9UQ35 S883C Neutral Neutral Q9UQ35 P804T Neutral Neutral P39059 P531R Neutral Neutral P39059 K1001R Neutral Neutral P39059 M204V Neutral Neutral P39059 T391M Neutral Neutral P39059 V1332I Neutral Neutral P39059 K989R Neutral Neutral P39059 R163H Neutral Disease P39059 A442T Neutral Neutral P39059 E506D Neutral Neutral P39059 G446R Neutral Neutral Q13126 V56I Neutral Neutral Q5JSH3 A289T Neutral Neutral Q5JSH3 T296A Neutral Neutral P43007 G37R Neutral Neutral Q15758 V512L Neutral Neutral Q15758 P17A Neutral Neutral P43007 V399I Neutral Neutral Q96C34 L397M Neutral Neutral Q96C34 V4I Neutral Neutral Q96C34 R160W Neutral Neutral P19438 S115G Disease Neutral P19438 C99S Disease Disease P19438 C59R Disease Disease P19438 H51Q Disease Neutral P19438 C62G Disease Disease P19438 T79M Disease Neutral P19438 R121Q Disease Neutral P19438 C117Y Disease Disease P19438 R121P Disease Disease P19438 C81F Disease Disease P19438 P75L Disease Neutral P19438 P305T Neutral Neutral P19438 C59S Disease Disease P19438 C62Y Disease Disease P19438 C117R Disease Disease Q8NCK7 D127G Neutral Neutral Q5TIE3 S506N Neutral Neutral Q5TIE3 A319S Neutral Neutral Q5TIE3 K634R Neutral Neutral Q5TIE3 N469S Neutral Neutral Q9NUQ3 I246V Neutral Neutral P63211 E50K Neutral Neutral Q86UD1 R217H Neutral Neutral Q86UD1 H210R Neutral Neutral Q9Y6X5 I255V Neutral Neutral Q9Y6X5 H144Q Neutral Neutral Q9Y6X5 S439A Neutral Neutral Q8TEE6 R68C Neutral Disease Q8TEE6 F755L Neutral Neutral Q8TEE6 K606N Neutral Neutral O43586 A230T Disease Neutral O43586 A151S Neutral Neutral O43586 E155D Neutral Neutral O43586 Q156H Neutral Neutral O43586 Q146H Neutral Neutral O43586 E250Q Disease Disease O43586 R149L Neutral Neutral O43586 E106K Neutral Disease O43586 Q48H Neutral Neutral P57796 R124C Disease Neutral Q9NQX4 P522L Neutral Neutral Q9Y4I1 R1246C Neutral Disease Q9NQX4 L634S Neutral Neutral Q9NQX4 E1075K Neutral Neutral P11388 T1324K Neutral Neutral Q6ZN32 S19A Neutral Neutral Q6ZN32 G263A Neutral Neutral Q6ZN32 M318V Neutral Neutral Q12931 R307G Neutral Disease Q9NQS1 Q228R Neutral Neutral Q49MG5 R177W Neutral Neutral Q5JSL3 I813F Neutral Disease A6NJ78 A149T Neutral Disease A6NJ78 N31K Neutral Neutral P11586 L769F Neutral Neutral P11586 R653Q Neutral Disease P11586 R293H Neutral Disease P11586 T761M Neutral Disease P11586 R134K Neutral Neutral Q9NR45 E68D Neutral Neutral Q9P126 S28F Neutral Disease Q9P126 I20V Neutral Neutral Q9P126 S24P Neutral Neutral Q9P126 G64D Neutral Neutral Q9GZU5 F298S Disease Disease Q9GZU5 N264K Disease Neutral Q9GZU5 A187K Disease Neutral Q9GZU5 L307P Disease Disease Q9GZU5 L232P Disease Disease Q9GZU5 N216S Disease Neutral Q9GZU5 L347P Disease Disease Q9GZU5 P151L Disease Neutral Q9GZU5 L184P Disease Disease Q9GZU5 N312S Disease Disease Q9GZU5 L285P Disease Disease Q9GZU5 C31S Disease Disease Q9GZU5 G370V Disease Disease Q9GZU5 P175R Disease Neutral Q9GZU5 A143P Disease Neutral Q9GZU5 L213Q Disease Neutral Q6PIW4 V137M Neutral Neutral Q6PIW4 H216Y Neutral Neutral Q14980 Y1836H Neutral Neutral Q14980 K242R Neutral Neutral Q14980 A794G Neutral Neutral Q14980 V1825M Neutral Neutral Q14980 E1153D Neutral Neutral Q96IQ9 P77S Neutral Neutral Q96IQ9 Q65R Neutral Neutral P28347 Y421H Disease Disease Q6PI48 L10V Neutral Neutral Q6PI48 Y629C Disease Neutral Q6PI48 L626Q Disease Disease Q6PI48 K196R Neutral Neutral Q6PI48 Q184K Disease Disease Q6PI48 C152F Disease Neutral Q6PI48 L613F Disease Disease Q6PI48 L626V Disease Disease Q6PI48 S45G Disease Neutral Q6PI48 Q248K Disease Disease Q6PI48 D560V Disease Neutral Q6PI48 R179H Disease Disease Q6PI48 R263Q Disease Disease O15488 H313R Neutral Neutral O15488 R373C Neutral Neutral O15488 A270V Neutral Neutral Q9NYL5 R23P Neutral Disease Q9NYL5 Y288H Neutral Neutral Q9NYL5 N324K Neutral Disease Q9NYL5 R103H Neutral Disease Q9UDY2 E482D Neutral Neutral Q9UDY2 V48A Disease Neutral O95409 Q36P Disease Neutral O95409 D152F Disease Disease Q9H6K4 G93S Disease Neutral Q9H6K4 Q105E Disease Neutral Q5T280 T130R Neutral Neutral Q5T280 I369T Neutral Neutral Q68CZ6 I586T Neutral Neutral Q9H321 K15T Neutral Neutral Q8IZS6 V121A Neutral Neutral Q8IZS6 I67V Neutral Neutral Q8IZS6 R88I Neutral Neutral O00295 A18T Neutral Neutral O00295 E245K Neutral Neutral O00295 D251N Neutral Neutral Q6UVJ0 A259V Neutral Neutral P01579 R160Q Neutral Neutral P01579 K29Q Neutral Neutral P35558 M60T Neutral Disease P35558 V368I Neutral Neutral P35558 T138I Neutral Disease Q16822 R31Q Neutral Neutral P35558 I267V Neutral Neutral P35558 R55Q Neutral Neutral Q16822 D64N Neutral Disease Q16822 G406S Neutral Disease P35558 E276K Neutral Neutral P35558 E586D Neutral Neutral P35558 V184L Neutral Neutral P35558 P427S Neutral Disease Q9ULM0 H735R Neutral Neutral Q9ULM0 R322Q Neutral Neutral Q9ULM0 N75S Neutral Neutral Q9ULM0 M438V Neutral Neutral Q9ULM0 T430A Neutral Neutral Q9ULM0 Q113L Neutral Neutral Q6ZV77 K168E Neutral Neutral P35212 V130I Neutral Neutral P35212 A128V Neutral Neutral P35212 P71S Neutral Disease P35212 P319S Neutral Neutral P13637 T613M Disease Disease P50993 W887R Disease Disease P20648 V265A Neutral Neutral P54707 P866L Neutral Disease P50993 L764P Disease Disease P50993 M731T Disease Disease P13637 I758S Disease Disease P13637 I274T Disease Disease P13637 D801Y Disease Disease P50993 T378N Disease Neutral P13637 E277K Disease Neutral P13637 F780L Disease Neutral P50993 R689Q Disease Disease P36969 S2N Neutral Neutral P36969 A120T Disease Disease Q9BQ75 V166I Neutral Neutral Q6ZTY8 V783A Neutral Neutral Q6ZTY8 G387S Neutral Disease Q6ZTY8 K666E Neutral Neutral Q6ZTY8 P593L Neutral Neutral Q6ZTY8 N790S Neutral Neutral Q6ZTY8 P1107H Neutral Neutral Q6ZTY8 E710K Neutral Neutral O15315 V9M Neutral Neutral O15315 Y180C Neutral Neutral O15315 K243R Neutral Neutral O15315 F82C Neutral Neutral O15315 V207L Neutral Neutral O15315 S250A Neutral Neutral O15315 L172W Neutral Disease Q99873 L158F Neutral Disease Q99873 K78M Neutral Disease Q5T3U5 I948T Neutral Neutral Q9Y6R1 R342S Disease Disease Q9Y6R1 A843V Disease Disease Q9Y6R1 R554H Disease Disease Q9Y6R1 R925C Disease Disease Q9Y6R1 T529S Disease Disease Q9Y6R1 S471L Disease Disease Q7Z4W2 D144G Neutral Neutral O75951 F139S Neutral Neutral P61626 T88N Neutral Disease Q6UWQ5 Q62P Neutral Disease P61626 D85H Disease Disease P00709 I46V Neutral Neutral P61626 I74T Disease Disease Q9H171 E88K Neutral Neutral Q9UGQ3 T500M Neutral Neutral Q96EM0 A315V Neutral Neutral Q96EM0 I341V Neutral Neutral Q96EM0 V42A Neutral Neutral Q9HB21 T320A Neutral Neutral Q8IYU2 R17H Neutral Disease Q8IYU2 I374T Neutral Neutral Q9H694 G8D Neutral Neutral Q9H694 S943P Neutral Neutral Q9NRD8 Q36H Disease Disease Q9NRD9 L1178F Neutral Neutral Q9NRD8 P138L Neutral Disease Q9NRD9 C1026R Neutral Neutral Q9NRD8 R376W Disease Disease P52747 E549Q Neutral Neutral P36508 T48M Neutral Neutral P36508 R272C Neutral Neutral P36508 R403Q Neutral Neutral O94810 M427T Neutral Neutral Q8NA72 I85T Neutral Neutral Q8NA72 H36R Neutral Neutral P49335 R330S Disease Disease P49335 L317W Disease Disease P49335 A312V Disease Disease P49335 R323G Disease Disease P49335 K334E Disease Disease Q96JX3 S543T Neutral Neutral Q5TEU4 L337F Neutral Neutral Q9BZ11 L612H Neutral Neutral Q9BZ11 A365S Neutral Neutral Q9BZ11 V710I Neutral Neutral Q9BZ11 D441E Neutral Disease Q9BZ11 P336S Neutral Neutral Q9BZ11 D742Y Neutral Disease Q9BZ11 M764T Neutral Neutral Q9BZ11 W515R Neutral Disease Q9BZ11 T272M Neutral Disease Q9BZ11 N109S Neutral Neutral Q9BZ11 C739G Neutral Neutral Q9BZ11 T178A Neutral Neutral Q9BZ11 V316I Neutral Neutral Q9BZ11 P774S Neutral Neutral P04181 L437F Neutral Neutral P04181 C394R Disease Disease P04181 P417L Disease Disease P04181 T267I Disease Disease P04181 Y245C Disease Disease P04181 N89K Disease Disease P04181 C93F Disease Disease P04181 P241L Disease Disease P04181 A226V Disease Disease P04181 R180T Disease Disease P04181 G353D Disease Disease P04181 R250P Disease Disease P04181 Y55H Disease Disease P04181 L402P Disease Disease P04181 Q90E Disease Neutral P04181 V332M Disease Disease P04181 R271K Disease Disease P04181 N54K Disease Disease P04181 H319Y Disease Disease P04181 G375A Disease Disease P04181 R154L Disease Disease P04181 A270P Disease Disease Q6WRI0 Y150D Neutral Neutral Q6WRI0 Y1875H Neutral Neutral Q6WRI0 T124I Neutral Neutral Q6WRI0 P571S Neutral Disease Q6WRI0 H2579Y Neutral Neutral Q6WRI0 S1199A Neutral Neutral Q6WRI0 T1370I Neutral Neutral Q6WRI0 R2476W Neutral Disease Q13164 G549A Neutral Neutral O43572 R249H Neutral Neutral O43572 I646V Neutral Neutral P58335 P357A Neutral Neutral P58335 L45P Disease Disease P58335 I189T Disease Disease P58335 Y381C Disease Disease P58335 L329R Disease Disease P58335 G105D Disease Disease P58335 C218R Disease Disease Q12788 S343P Neutral Neutral Q12788 P336R Neutral Neutral Q9Y5Y5 V254L Neutral Neutral Q92791 Q186R Neutral Neutral Q6P2D8 T473R Neutral Neutral Q8IWD4 S272N Neutral Neutral Q8IWD4 R147S Neutral Neutral P19971 K222R Disease Disease P19971 G145R Disease Disease P19971 E289A Disease Disease P19971 R44Q Disease Disease P19971 G153S Disease Disease P19971 S471L Neutral Neutral Q9H0F7 G169A Disease Disease Q9H0F7 T31M Disease Disease P36405 L34M Neutral Disease Q9H0F7 T31R Disease Disease Q969Q4 E164K Neutral Disease Q969Q4 S22L Neutral Disease P49703 T91N Neutral Disease Q969Q4 C148R Neutral Disease P36404 V141A Neutral Neutral Q969Q4 P131L Neutral Disease P40617 R139K Neutral Neutral Q9H0F7 L170W Disease Disease Q6P9G4 S93F Neutral Disease Q14694 S203P Neutral Neutral Q14694 V204L Neutral Neutral Q14694 M200V Neutral Neutral Q14739 T311A Neutral Neutral Q14739 P569R Disease Disease Q14739 P119L Disease Disease Q14739 S154N Neutral Neutral Q96KN7 Q1033E Neutral Neutral Q96KN7 G746E Disease Disease Q96KN7 A547S Disease Neutral Q96KN7 D1114G Disease Neutral Q96KN7 S601L Neutral Neutral Q96KN7 R827L Disease Disease Q96KN7 K192E Neutral Neutral P43657 I33V Neutral Neutral P43657 C137W Neutral Disease P49257 V39A Neutral Neutral P49257 R14Q Neutral Neutral P49257 M410L Neutral Neutral Q9BPW8 E245K Neutral Neutral P51688 L386R Disease Disease P51688 Y40N Disease Disease P51688 A354P Disease Disease P51688 S66W Disease Neutral P51688 R74H Disease Disease P51688 D235V Disease Disease P51688 A234G Disease Neutral P51688 R182C Disease Disease P51688 R74C Disease Disease P51688 D179N Disease Neutral P51688 Q380R Disease Neutral P51688 A44T Disease Neutral P51688 T139M Disease Neutral P51688 T321A Disease Disease P51688 R206P Disease Disease P51688 R377C Disease Disease P51688 V361I Neutral Neutral P51688 R150Q Disease Neutral P51688 S364R Disease Neutral P51688 E369K Disease Neutral P51688 V226A Neutral Neutral P51688 G122R Disease Disease P51688 G90R Disease Disease P51688 L146P Disease Disease P51688 S298P Disease Disease P51688 N389K Disease Disease P51688 R456H Neutral Neutral P51688 V131M Disease Neutral P51688 F193L Disease Disease P51688 P128L Disease Disease P51688 R245H Disease Neutral P51688 R377H Disease Disease P51688 Q85R Disease Neutral P51688 E447K Disease Disease P51688 T79P Disease Disease P51688 P227R Disease Disease Q9H6T0 A528V Neutral Neutral Q9H6T0 S111L Neutral Neutral Q6NXG1 Y196C Neutral Neutral P07741 M136T Disease Disease P07741 Q121R Neutral Disease P07741 C153R Disease Disease P07741 V150F Disease Disease P07741 D65V Disease Disease P07741 L110P Disease Disease Q8IYB3 R170H Neutral Neutral Q16719 K412E Neutral Neutral P09467 K218R Neutral Neutral P09467 F194S Disease Disease P09467 P284R Disease Disease P09467 F233I Neutral Neutral P09467 V325A Neutral Disease P09467 A177D Disease Disease P09467 R255L Neutral Disease O00757 V86L Neutral Neutral P09467 G164S Disease Disease Q49AM1 A81G Neutral Neutral Q49AM1 L14V Neutral Neutral Q6STE5 P170S Neutral Neutral Q9NRL2 D344E Neutral Neutral Q8N0U2 E40K Neutral Neutral Q3YEC7 E382Q Neutral Neutral Q9HCU4 Y1639H Neutral Neutral Q9NYQ6 S664W Neutral Neutral Q9NYQ6 C1126R Neutral Neutral Q9NYQ6 I2107V Neutral Neutral Q9NYQ6 T2268A Neutral Neutral Q9NYQ7 S805T Neutral Neutral Q9NYQ7 A157P Neutral Neutral Q8NDZ0 F154L Neutral Neutral P49642 D5A Neutral Neutral A0FGR9 G416R Neutral Disease A0FGR9 P246Q Neutral Disease Q9NZQ8 V254A Neutral Neutral Q12805 R345W Disease Disease Q12805 I220F Neutral Neutral P39210 R50Q Disease Disease P39210 R50W Disease Disease P39210 N166K Disease Disease Q9Y3D3 Y12H Neutral Disease Q92481 R285Q Disease Disease Q92481 A275D Disease Disease Q92481 R236S Disease Disease Q92481 R236C Disease Disease Q92481 P73R Disease Neutral Q92481 R300C Disease Disease Q9BXF3 P674L Neutral Neutral Q9BXF3 R293H Neutral Neutral Q8N412 V420A Neutral Neutral Q8N412 C111W Neutral Neutral Q8N412 K279R Neutral Neutral Q8N412 Y125H Neutral Disease Q8N412 I178V Neutral Neutral Q8N412 F112V Neutral Neutral Q14773 V208L Neutral Neutral O95872 A235V Neutral Neutral Q9NS25 V74L Neutral Neutral Q9NY87 V59F Neutral Neutral Q8TAD1 V68L Neutral Neutral Q9BXN6 V68L Neutral Neutral Q9NY87 V59L Neutral Neutral O75444 R288P Disease Disease O75444 K297R Disease Disease O75626 G38S Neutral Neutral O75626 D167E Neutral Neutral Q9NXR5 P320L Neutral Neutral P02763 Q38R Neutral Neutral P19652 R38Q Neutral Neutral P02763 V174M Neutral Neutral Q86XA0 L141V Neutral Neutral Q9P212 H1927R Neutral Neutral Q9P212 S1484L Disease Disease Q9P212 T1777I Neutral Neutral Q9P212 S469T Neutral Neutral Q9P212 R1575P Neutral Neutral Q9P212 R548L Neutral Neutral Q8N865 Y82C Neutral Neutral Q8N865 S187T Neutral Neutral Q8N865 T158A Neutral Neutral Q8N865 H300R Neutral Neutral Q9NRH1 K68E Neutral Neutral Q15762 G307S Neutral Neutral Q9BQG0 Q8E Neutral Neutral Q96A84 A107G Neutral Neutral P50391 A99S Neutral Neutral P50391 R240C Neutral Neutral Q6ICB4 A188G Neutral Neutral Q9H777 M355V Neutral Neutral Q8N323 I423T Neutral Disease Q8N323 G353R Neutral Disease Q14005 N446K Neutral Disease Q14005 S205L Neutral Neutral Q14005 R188Q Neutral Neutral Q14005 S326T Neutral Neutral O95757 N216T Neutral Neutral O95757 S211L Neutral Disease Q8WWC4 L290I Neutral Neutral P38398 P871L Neutral Neutral P38398 P1776S Disease Neutral P38398 E1210G Disease Disease P38398 H888Y Disease Neutral P38398 I925L Neutral Neutral P38398 E10K Disease Neutral P38398 G275S Neutral Disease P38398 R1443Q Neutral Neutral P38398 R1699W Disease Disease P38398 L22S Disease Neutral P38398 P1812S Disease Neutral P38398 E227K Disease Neutral P38398 K1406N Neutral Neutral P38398 T1620A Neutral Neutral P38398 F989S Neutral Neutral P38398 S1613G Neutral Neutral P38398 M1775R Disease Disease P38398 R1443G Neutral Neutral P38398 R1347G Neutral Neutral P38398 C61G Disease Neutral P38398 Y856H Disease Disease P38398 D693N Neutral Neutral P38398 Y465D Disease Disease P38398 D1692N Disease Disease P38398 A1708E Disease Disease P38398 R841W Disease Neutral P38398 P346S Disease Neutral P38398 S1140G Neutral Neutral P38398 M1652I Neutral Neutral P38398 T1025I Disease Neutral P38398 V1047A Disease Neutral P38398 R866Q Disease Disease P38398 M1008I Neutral Neutral P38398 H239R Neutral Neutral P38398 F1226L Disease Disease P38398 V772A Neutral Disease P38398 E1038G Neutral Disease P38398 K1207N Disease Disease P38398 V1713G Neutral Disease P38398 C64G Disease Neutral P38398 Q1200H Disease Disease P38398 S1297P Disease Disease P38398 R71K Disease Neutral P38398 H835Y Disease Disease P38398 T826K Disease Disease P38398 V1665M Neutral Neutral P38398 K1183R Neutral Neutral P38398 P1637L Neutral Neutral P38398 C1697R Disease Disease P38398 P1749R Disease Neutral P38398 N723D Neutral Neutral P38398 P1150S Disease Disease P38398 S1187I Disease Disease P38398 Q356R Neutral Disease P38398 M1411T Disease Disease P38398 M1628T Disease Neutral P38398 L1786P Disease Disease P38398 V271M Disease Neutral P38398 S1512I Neutral Neutral P38398 R1243G Disease Neutral P38398 L892S Disease Disease P38398 K820E Neutral Disease P38398 S1217Y Disease Neutral P38398 S1040N Neutral Neutral P38398 S1431P Neutral Neutral P38398 G960D Disease Disease P38398 G552V Disease Disease P38398 K1690Q Disease Neutral P38398 E23K Disease Neutral P38398 D749Y Disease Disease P38398 A1641P Disease Neutral P38398 N656I Neutral Disease P38398 S1139I Disease Disease P38398 F461L Disease Disease P38398 E1060A Neutral Disease P38398 R1204I Disease Disease Q18PE1 P415S Neutral Neutral Q18PE1 G180A Disease Neutral Q18PE1 G427D Neutral Neutral Q18PE1 G461D Neutral Neutral Q18PE1 R158Q Neutral Neutral Q18PE1 R261H Neutral Neutral Q18PE1 Q296R Neutral Neutral Q18PE1 D197N Neutral Neutral Q18PE1 R451W Neutral Neutral Q17R60 R704W Neutral Neutral Q17R60 H518D Neutral Neutral Q9NS62 V125G Neutral Disease Q9NS62 R224G Neutral Neutral Q9NS62 K768R Neutral Neutral Q86VF7 S490L Neutral Neutral Q86VF7 A1112V Neutral Disease Q86VF7 Q360R Neutral Neutral Q86VF7 R884C Neutral Disease Q86VF7 Y249C Neutral Disease Q86VF7 L1531P Neutral Disease Q86VF7 A674V Neutral Neutral Q86VF7 A282T Neutral Neutral Q86VF7 Q186E Neutral Neutral Q86VF7 V208A Neutral Neutral Q86VF7 A132S Neutral Neutral Q86VF7 A344T Neutral Neutral Q86VF7 N519I Neutral Neutral Q8WVF1 K232E Neutral Neutral Q8WVF1 P31R Neutral Neutral O94953 N29T Neutral Neutral O94953 K710E Neutral Neutral Q2M3D2 N173D Neutral Neutral Q9NV06 N70S Neutral Neutral Q9NV06 I42V Neutral Neutral Q6NZ63 R166M Neutral Disease Q6NZ63 I210T Neutral Neutral Q6NZ63 Q29R Neutral Neutral Q6NZ63 I7V Neutral Neutral Q86X52 Q652H Neutral Disease Q86X52 P359S Neutral Neutral A4QPH2 E223Q Neutral Disease A4D0V7 I326T Neutral Neutral A4D0V7 E708G Neutral Neutral A4D0V7 K949T Neutral Neutral A4D0V7 A551G Neutral Neutral Q9H7H0 A346P Neutral Disease Q9H7H0 G289A Neutral Neutral Q2M2E3 W34R Neutral Neutral Q2M2E3 V98M Neutral Neutral Q2M2E3 Y139C Neutral Neutral Q9P1Z2 R393K Neutral Neutral Q9BVG8 G391V Neutral Neutral P42226 M181R Neutral Neutral P04156 V180I Disease Neutral P04156 T188R Neutral Neutral P04156 Q217R Disease Disease P04156 P105L Disease Neutral P04156 F198S Disease Disease P04156 Q212P Disease Disease P04156 E211Q Disease Neutral P04156 E219K Neutral Neutral P04156 M129V Neutral Neutral P04156 H187R Disease Neutral P04156 V203I Disease Neutral P04156 V210I Disease Neutral P04156 E200K Disease Neutral P04156 D178N Disease Disease P04156 E196K Disease Neutral P04156 M232R Disease Neutral P04156 P238S Neutral Neutral P04156 P102L Disease Neutral P04156 R208H Disease Disease P04156 D202N Disease Neutral P04156 N171S Neutral Neutral P04156 G131V Disease Disease P19404 V29A Neutral Neutral Q6NUM9 A533V Neutral Neutral Q68CQ4 Q67E Neutral Neutral Q86T26 V242I Neutral Neutral Q6ZMR5 R293Q Neutral Neutral Q6ZWK6 A4T Neutral Neutral Q86T26 S348T Neutral Neutral Q9GZP7 A269D Neutral Neutral Q9GZP7 S241F Neutral Disease Q9GZP7 I139T Neutral Neutral O75027 I400M Disease Disease O75027 F346I Neutral Disease O75027 R315G Neutral Neutral O75027 E433K Disease Disease O75027 V581A Neutral Neutral O75027 V411L Disease Disease Q5TGP6 Y160H Neutral Neutral Q5TGP6 V74A Neutral Neutral Q5TGP6 N29S Neutral Neutral Q9NY99 S168Y Neutral Neutral Q9NY99 S200L Neutral Neutral Q9NY99 I391V Neutral Neutral P33908 R651G Neutral Neutral Q2M3G4 P180L Neutral Neutral P51810 G35D Disease Neutral P51810 E271G Disease Neutral P51810 A173D Disease Neutral P51810 Q124R Disease Disease P51810 A138V Disease Disease P51810 T232K Disease Disease P51810 C116R Disease Disease P51810 G229V Disease Disease P51810 R5C Disease Neutral P51810 I244V Disease Neutral P51810 L39R Disease Disease P51810 D78V Disease Disease P51810 E235K Disease Neutral P51810 G84D Disease Disease P51810 C116S Disease Disease P51810 W133R Disease Disease P51810 W292C Disease Disease P51810 G84R Disease Disease P51810 E233K Disease Neutral P51810 I261N Disease Disease P51810 S152N Disease Neutral P51810 G118E Disease Disease P51810 D78N Disease Neutral P51810 W292G Disease Disease Q9UKT4 Q107E Neutral Neutral Q659C4 R660H Neutral Neutral Q659C4 P462R Neutral Neutral Q9HBT7 K274T Neutral Neutral Q96S42 R183Q Disease Neutral Q8WVB3 I145V Neutral Neutral P41440 H27R Neutral Neutral Q5T0J7 L171R Neutral Disease Q5T0J7 A146G Neutral Neutral Q5T0J7 E55G Neutral Neutral P26012 S552F Neutral Disease Q6P4A8 V376A Neutral Neutral Q6P4A8 A533P Neutral Neutral Q6P4A8 I264V Neutral Neutral Q8NHP8 R524C Neutral Neutral Q6ZP80 R223W Neutral Disease Q53TQ3 A358V Neutral Neutral Q13227 T306A Neutral Neutral Q92664 V245L Neutral Neutral Q7Z3B0 L23F Neutral Neutral Q7Z4G4 L230Q Neutral Disease P07357 E561Q Neutral Neutral P07357 Q93K Neutral Neutral P07357 P575L Neutral Neutral P07357 R485L Neutral Disease P07357 D458N Neutral Neutral P07357 T407I Neutral Neutral P07359 C81R Disease Disease P07359 C225S Disease Disease P07359 T161M Neutral Neutral P07359 L73F Disease Disease P07359 A254S Neutral Neutral P07359 L145P Disease Disease P07359 R72H Neutral Neutral P07359 L86F Neutral Disease P07359 A172V Disease Neutral Q8NDM7 I394T Neutral Neutral Q8NDM7 A836S Neutral Neutral Q8NDM7 V635I Neutral Neutral Q8NDM7 L617F Neutral Neutral Q15049 N141S Disease Neutral Q15049 S280L Disease Disease Q15049 N141K Disease Neutral Q15049 G212R Disease Disease Q15049 T118R Disease Disease Q15049 P92S Disease Neutral Q15049 S93L Disease Neutral Q15049 L309M Disease Neutral Q15049 G59E Disease Disease Q6P3R8 R290H Neutral Neutral Q6P3R8 C531R Neutral Neutral O75592 V2588M Neutral Neutral Q05209 K61R Disease Disease Q05209 I322V Neutral Neutral Q05209 T573A Neutral Neutral Q6SA08 Y89C Neutral Neutral Q6SA08 V145M Neutral Neutral Q6SA08 H33Y Neutral Disease Q6SA08 Q196R Neutral Neutral Q6SA08 T327M Neutral Neutral P36955 P132R Neutral Disease P36955 M72T Neutral Neutral O14880 P48S Neutral Neutral O14880 G15C Neutral Neutral P55957 S10G Neutral Neutral P55957 H162Q Neutral Neutral Q8TB22 R609K Neutral Neutral Q8TB22 S483T Neutral Neutral Q8TB22 Q88E Neutral Neutral P43699 W208L Disease Disease P43699 R213S Disease Disease P43699 V205F Disease Disease Q7L3B6 S291F Neutral Neutral Q86YW9 Q401P Neutral Neutral Q86YW9 Q903H Neutral Neutral Q86YW9 R1698Q Neutral Disease Q86YW9 R1210Q Neutral Neutral Q86YW9 E464K Neutral Disease P30536 A147T Neutral Disease P30536 E169Q Neutral Neutral P30536 H162R Neutral Neutral P20023 S639N Neutral Disease P20023 I993V Neutral Neutral P20023 E1003A Neutral Neutral Q9UNY4 K167E Neutral Neutral Q9UNY4 K213R Neutral Neutral Q96M32 R102Q Neutral Neutral Q9P281 T1298A Neutral Neutral Q8WUT9 L334P Neutral Neutral Q8N5U6 E433D Neutral Neutral Q8N5U6 L332F Neutral Neutral P37231 R316H Disease Neutral P37231 Q314P Disease Neutral P37231 R425C Disease Disease P37231 F388L Disease Neutral P37231 P12A Neutral Neutral P37231 P113Q Disease Disease P37231 P40A Neutral Neutral Q8TCI5 K97N Neutral Neutral Q8TCI5 H105N Neutral Neutral Q9UIS9 P401A Neutral Neutral Q14643 M769V Neutral Disease Q14643 I1430V Neutral Neutral Q9UHK6 V9M Neutral Disease Q9UHK6 G175D Neutral Disease Q9UHK6 S201L Neutral Neutral Q9UHK6 L107P Disease Disease Q9UHK6 S52P Disease Disease Q9UHK6 K277E Neutral Neutral Q8N205 S224L Neutral Neutral Q8N205 Q278H Neutral Neutral Q6KF10 K110E Neutral Neutral Q13753 D247E Neutral Neutral Q13753 S733T Neutral Neutral Q7RTX7 Q77R Neutral Neutral Q7RTX7 I293V Neutral Neutral Q7RTX7 L124F Neutral Neutral Q7RTX7 D436N Neutral Neutral Q8N3Z0 R224Q Neutral Neutral Q7L2K0 R346K Neutral Neutral P13569 R560T Disease Disease P13569 R117H Disease Neutral P13569 A1067T Disease Neutral P13569 Y569C Disease Neutral P13569 P67L Disease Neutral P13569 C225R Disease Disease P13569 G551D Disease Disease P13569 R668C Neutral Disease P13569 H199Q Disease Disease P13569 S1251N Disease Disease P13569 I618T Disease Neutral P13569 L558S Disease Disease P13569 E504Q Disease Neutral P13569 Y913C Disease Disease P13569 L346P Disease Disease P13569 I336K Disease Disease P13569 R170H Neutral Neutral P13569 L571S Disease Disease P13569 R297Q Disease Disease P13569 R347H Disease Disease P13569 G178R Disease Disease P13569 N287Y Disease Neutral P13569 R258G Disease Disease P13569 L206W Disease Disease P13569 L610S Disease Neutral P13569 Q1291H Disease Disease P13569 V456F Disease Disease P13569 V562L Disease Neutral P13569 A1067V Neutral Disease P13569 G628R Disease Disease P13569 I601F Disease Disease P13569 E822K Disease Neutral P13569 D44V Neutral Disease P13569 R1283M Disease Disease P13569 G1349D Disease Disease P13569 V754M Disease Neutral P13569 G314E Disease Disease P13569 Q1071P Disease Neutral P13569 R334W Disease Disease P13569 H1085R Disease Neutral P13569 V322M Neutral Disease P13569 R560K Disease Disease P13569 P205S Disease Disease P13569 Y569D Disease Disease P13569 S182G Neutral Disease P13569 N1303K Disease Disease P13569 W1098R Disease Disease P13569 G544V Disease Disease P13569 N1303H Disease Disease P13569 S50Y Disease Neutral P13569 P574H Disease Neutral P13569 C866Y Disease Disease P13569 A120T Disease Neutral P13569 I1234V Disease Neutral P13569 D648V Disease Disease P13569 Y301C Disease Disease P13569 V470M Neutral Neutral P13569 A559T Disease Disease P13569 E92K Disease Disease P13569 W1282R Disease Disease P13569 L633P Disease Disease P13569 G314R Disease Disease P13569 R75Q Neutral Disease P13569 R347L Disease Disease P13569 S549I Disease Disease P13569 L138P Neutral Disease P13569 G458V Disease Disease P13569 Y569H Disease Neutral P13569 V520F Disease Disease P13569 I807M Disease Neutral P13569 S549N Disease Disease P13569 H199Y Disease Disease P13569 A1364V Disease Neutral P13569 R347P Disease Disease P13569 S654G Neutral Neutral P13569 P1072L Disease Neutral P13569 G1249E Disease Disease P13569 L1077P Disease Disease P13569 R352Q Disease Neutral P13569 R1070P Disease Disease P13569 S1255P Disease Disease P13569 F87L Disease Neutral P13569 H949Y Disease Disease P13569 P111L Disease Disease P13569 L467F Neutral Disease P13569 G480C Disease Disease P13569 R1070Q Disease Neutral P13569 L967S Neutral Neutral P13569 R766M Disease Neutral P13569 S1235R Disease Neutral P13569 T1220I Neutral Neutral P13569 G551S Disease Disease P13569 A800G Disease Neutral P13569 R117P Disease Disease P13569 M1028I Disease Neutral P13569 L1065P Disease Disease P13569 S42F Disease Neutral P13569 F311L Disease Disease P13569 D1270N Disease Disease P13569 I105S Disease Disease P13569 M1101K Disease Disease P13569 G85E Disease Disease P13569 W57G Disease Disease P13569 F1286S Disease Neutral P13569 R553Q Disease Neutral P13569 S549R Disease Disease P13569 S909I Neutral Disease P13569 T338I Disease Disease P13569 Y563N Disease Neutral P13569 A455E Disease Disease P13569 H620P Disease Disease P13569 G1244E Disease Disease P13569 R31C Neutral Disease P13569 R74W Disease Disease P13569 V1397E Disease Disease P13569 R1066H Disease Disease P13569 D44G Disease Disease P13569 D513G Disease Neutral P13569 R1070W Disease Disease P13569 S307N Disease Disease P13569 I148T Disease Neutral P13569 A141D Disease Disease P13569 D110H Disease Neutral P13569 M244K Disease Neutral P13569 E193K Disease Disease P13569 Y917C Disease Disease P13569 Q98R Disease Disease P13569 M1137V Disease Neutral P13569 F508C Neutral Disease P13569 Q353H Neutral Disease P13569 I506V Neutral Neutral P13569 M1101R Disease Disease P13569 D614G Disease Disease P13569 G91R Disease Disease P13569 S492F Disease Neutral P13569 L619S Disease Disease P13569 H620Q Disease Neutral P13569 L1065R Disease Disease P13569 I507V Neutral Neutral P13569 A613T Disease Disease P13569 G576A Neutral Neutral P13569 R560S Disease Disease P13569 R1066C Disease Disease P13569 I1005R Disease Disease P13569 D1152H Disease Neutral P13569 P1013L Disease Disease P13569 G1061R Disease Disease P13569 Q1291R Disease Disease P13569 R117C Disease Disease P13569 V562I Neutral Neutral P13569 G149R Disease Disease P13569 R117L Disease Disease P13569 F1052V Disease Neutral P13569 R1066L Disease Disease P13569 D651N Disease Neutral P13569 D572N Disease Disease P13569 Y903H Neutral Neutral P13569 Y109C Disease Disease P13569 R792G Disease Disease P13569 R31L Disease Disease P13569 D579G Disease Disease P13569 I506M Neutral Disease P13569 F693L Neutral Neutral P13569 R1162L Neutral Disease P13569 H139R Disease Disease P13569 S912L Neutral Disease P13569 Q359K Disease Neutral P13569 S13F Disease Disease P13569 L997F Disease Neutral P13569 M952I Disease Disease P13569 T351S Neutral Neutral P13569 T665S Disease Neutral P13569 A1006E Disease Disease Q2VPA4 N402D Neutral Neutral Q2VPA4 I139V Neutral Neutral Q2VPA4 G116R Neutral Disease Q2VPA4 V455I Neutral Neutral Q2VPA4 L491P Neutral Disease P51636 Q130E Neutral Neutral Q96DL1 V103A Neutral Neutral Q13309 P85L Neutral Disease Q13309 L87I Neutral Neutral Q86UV5 E135K Neutral Disease Q86UV5 S125C Neutral Neutral P14138 C159F Disease Disease P14138 Y127C Disease Disease P14138 A17T Disease Neutral P14138 A224T Disease Neutral Q9UIW0 P254R Neutral Neutral P06239 V28L Disease Neutral P12931 A237T Neutral Disease P07947 K282R Neutral Neutral P07947 I198V Neutral Neutral P06239 A353V Disease Disease P09769 T110I Neutral Disease P09769 S130R Neutral Disease P06239 P447L Disease Neutral P07949 R67H Disease Neutral P07949 C634G Disease Neutral P07949 C630F Disease Neutral P07949 C620S Disease Neutral P07949 C609W Disease Disease P07949 C630Y Disease Neutral P07949 C157Y Disease Neutral P07949 P1039Q Neutral Disease P07949 D489N Neutral Neutral P07949 C611G Disease Disease P07949 Y826S Neutral Disease P07949 E921K Disease Disease P07949 P20L Disease Neutral P07949 R231H Disease Disease P07949 R313Q Disease Neutral P07949 C634F Disease Neutral P07949 C620W Disease Disease P07949 R749T Neutral Neutral P07949 E768D Disease Neutral P07949 R844L Disease Disease P07949 R77C Disease Disease P07949 R114H Disease Neutral P07949 C618Y Disease Disease P07949 M980T Disease Neutral P07949 T946M Disease Disease P07949 V804L Disease Neutral P07949 L40P Disease Neutral P07949 F893L Disease Disease P07949 C620R Disease Disease P07949 M918T Disease Neutral P07949 F174S Disease Disease P07949 R330Q Disease Neutral P07949 C630S Disease Neutral P07949 R287Q Disease Neutral P07949 C609Y Disease Disease P07949 E251K Disease Neutral P07949 C620F Disease Neutral P07949 R813Q Disease Disease P07949 N394K Disease Disease P07949 G93S Disease Disease P07949 P399L Disease Disease P07949 C634W Disease Neutral P07949 T278N Neutral Disease P07949 A641G Disease Neutral P07949 G691S Neutral Neutral P07949 P64L Disease Neutral P07949 L1061P Disease Disease P07949 Y791F Disease Neutral P07949 C609G Disease Disease P07949 S922F Disease Disease P07949 R475Q Disease Neutral P07949 V292M Neutral Neutral P07949 S690P Disease Disease P07949 C634S Disease Neutral P07949 S767R Disease Neutral P07949 P973L Disease Disease P07949 C197Y Disease Disease P07949 C618R Disease Disease P07949 C609R Disease Disease P07949 C611S Disease Disease P07949 C634Y Disease Disease P07949 K907E Disease Neutral P07949 S891A Disease Neutral P07949 A640G Disease Neutral P07949 C620Y Disease Neutral P07949 N359K Disease Neutral P07949 R873Q Disease Disease P07949 C618F Disease Disease P07949 L790F Disease Disease P07949 C142S Disease Neutral P07949 P1039L Disease Neutral P07949 S32L Disease Neutral P07949 A432E Disease Neutral P07949 R897Q Disease Disease P07949 R360W Disease Neutral P07949 S765P Disease Disease P07949 R180P Disease Disease P07949 R600Q Neutral Neutral P07949 C618G Disease Disease P07949 A639G Disease Neutral P07949 F393L Disease Disease P07949 E762Q Disease Neutral P07949 C611W Disease Disease P07949 C611Y Disease Disease P07949 S922Y Neutral Disease P07949 M1064T Disease Neutral P07949 C620G Disease Neutral P07949 R972G Disease Neutral P07949 C618S Disease Neutral P07949 V804M Disease Neutral P07949 D631G Disease Neutral P07949 C634R Disease Disease P07949 Q626K Disease Neutral P07949 A883F Disease Disease P07949 C611R Disease Disease P07949 R982C Neutral Neutral Q9UNW1 S41L Disease Neutral P61927 G81E Neutral Disease Q6ZMJ4 E123Q Neutral Neutral O95972 Y235C Disease Disease Q8WVS4 Q273R Neutral Neutral Q8WVS4 E91G Neutral Neutral Q9BQS6 Q2P Neutral Neutral Q86WG3 S301R Disease Disease Q9BW19 R219Q Neutral Neutral Q9C0C9 G1207S Neutral Neutral O00767 M224L Neutral Neutral O95807 F141L Neutral Neutral O95807 A58V Neutral Neutral Q6ZS81 S944F Neutral Neutral Q6ZS81 S214P Neutral Neutral Q9UII6 Y156C Neutral Disease P98164 Y2522H Disease Disease Q14515 D49A Neutral Neutral O60315 R953G Disease Neutral O60315 Q1119R Disease Neutral P37275 K553R Neutral Neutral Q5SRN2 I150F Neutral Neutral Q5SRN2 I315V Neutral Neutral Q5SRN2 P161L Neutral Neutral Q5SRN2 Y69C Neutral Neutral Q5SRN2 Y36H Neutral Neutral Q5SRN2 S170P Neutral Neutral Q5SRN2 S227P Neutral Disease Q5SRN2 P128L Neutral Neutral Q5SRN2 R30C Neutral Neutral Q5SRN2 K400Q Neutral Neutral O95125 V154A Neutral Neutral O95125 G533A Neutral Neutral Q8IXY8 H110R Neutral Neutral Q9NWU5 G154S Neutral Neutral P02730 I442F Neutral Neutral P02730 P147S Disease Neutral P02730 P854L Neutral Disease P02730 V862I Neutral Neutral P02730 S773P Disease Disease P02730 G701D Disease Disease P02730 P327R Disease Neutral P02730 S690G Neutral Neutral P02730 S731P Disease Disease P02730 R760W Disease Disease P02730 R760Q Disease Disease P02730 I688V Neutral Neutral P02730 T837M Disease Disease P02730 R808C Disease Disease P02730 L687P Disease Disease P02730 E68K Neutral Neutral P02730 R518C Disease Disease P02730 D705Y Disease Disease P02730 R808H Disease Disease P02730 V488M Disease Neutral P02730 H734R Disease Disease P02730 E40K Neutral Neutral P02730 A285D Disease Disease P02730 L707P Disease Disease P02730 D45E Neutral Neutral P02730 R832H Neutral Disease P02730 R602P Disease Disease P02730 R589S Disease Neutral P02730 R112S Neutral Neutral P02730 P868L Disease Disease P02730 K56E Neutral Neutral P02730 G130R Disease Neutral P02730 L73M Neutral Neutral P02730 D38A Neutral Neutral P02730 G771D Disease Disease P02730 E90K Disease Disease P02730 E508K Neutral Disease P02730 R490C Disease Disease P02730 I783N Disease Disease P02730 R870W Disease Disease P02730 G455E Disease Disease P02730 T837A Disease Disease P02730 R589C Disease Disease P02730 A858D Disease Disease P02730 S613F Disease Disease P02730 M586L Neutral Neutral P02730 R589H Disease Disease P02730 G714R Disease Disease P02730 H834P Disease Disease Q6P9B6 V220I Neutral Neutral Q6P9B6 D172E Neutral Neutral Q6P9B6 H97Q Neutral Neutral Q6P9B6 R267C Neutral Disease Q6P9B6 S443L Neutral Neutral Q6P9B6 E233D Neutral Neutral Q6P9B6 R10L Neutral Neutral Q8N0V3 V122M Neutral Neutral Q8N0V3 K276Q Neutral Neutral Q8N0V3 N245H Neutral Neutral O43868 L163W Neutral Disease O43868 F355S Neutral Disease O43868 E385K Neutral Neutral O43868 G509E Neutral Disease O43868 S75R Neutral Neutral O43868 L12P Neutral Disease O00337 I189V Neutral Neutral O43868 S245T Neutral Neutral O43868 M612T Neutral Neutral O00337 E34G Neutral Neutral O43868 P22L Neutral Neutral O43868 L462F Neutral Disease O00337 N521D Neutral Neutral O00337 N409S Neutral Disease O43868 R142H Neutral Disease O43868 E172D Neutral Neutral Q5T5U3 E1628K Neutral Neutral Q5T5U3 V1610A Neutral Neutral Q5T5U3 T1593A Neutral Neutral Q5T5U3 S1949N Neutral Neutral Q5T5U3 N712S Neutral Neutral Q5T5U3 A1726T Neutral Neutral Q6P2C0 S254T Neutral Neutral Q6P2C0 L66H Neutral Neutral Q6P2C0 T352M Neutral Neutral Q9BY76 E196K Neutral Disease Q9BY76 R72L Neutral Neutral Q9BY76 R278Q Neutral Disease Q9BY76 P307S Neutral Neutral Q9BY76 R336C Neutral Neutral Q9BY76 M41I Neutral Neutral Q9BY76 W349C Neutral Disease Q9BY76 E167K Neutral Neutral Q9BY76 G77R Neutral Neutral Q9BY76 E190Q Neutral Disease Q9BY76 P174S Neutral Neutral Q9BY76 G361S Neutral Disease Q9BY76 E296V Neutral Disease Q9BY76 V308M Neutral Disease Q9BY76 S67R Neutral Neutral Q9BY76 R230C Neutral Disease Q9BY76 P5L Neutral Neutral Q9BY76 T266M Neutral Disease Q9BY76 G233R Neutral Disease Q9BY76 D338E Neutral Neutral Q9BY76 F237V Neutral Disease Q9BY76 R384W Neutral Disease Q9BY76 V291M Neutral Disease Q9BY76 R371Q Neutral Neutral Q9BY76 G361R Neutral Disease Q9BY76 P251T Neutral Neutral Q9BY76 L293M Neutral Neutral Q2M3C6 P427L Neutral Neutral Q2M3C6 R391H Neutral Neutral Q9UBH6 T491A Neutral Neutral Q6ZRI6 D491G Neutral Neutral Q6ZRI6 A119P Neutral Neutral Q6ZRI6 S536A Neutral Neutral Q6ZRI6 D945G Neutral Neutral P37198 A233S Neutral Neutral P37198 S283T Neutral Neutral P37198 G139S Neutral Neutral P37198 Q391P Disease Disease Q13627 Q681H Neutral Neutral Q13627 Y415F Neutral Neutral Q13627 A679P Neutral Neutral Q8TDV5 S309L Neutral Neutral Q9BXM7 G309D Disease Disease Q5JUK2 Q37R Neutral Neutral Q5JUK2 S269P Neutral Neutral Q5H8A3 P6S Neutral Neutral Q8WWF3 R88W Neutral Neutral O15269 C133Y Disease Disease O15269 G387A Disease Disease O15269 C133W Disease Disease O15269 V144D Disease Disease P41222 R56Q Neutral Neutral Q9UJS0 E601K Disease Disease Q13651 R212Q Neutral Neutral Q13651 G351R Neutral Neutral Q13651 L61V Neutral Neutral Q13651 S420L Neutral Neutral Q13651 S159G Neutral Neutral Q13651 I224V Neutral Neutral Q13651 V113I Neutral Neutral Q460N3 R315K Neutral Neutral Q460N3 G606R Neutral Disease P31213 R145W Disease Disease P31213 L113V Neutral Neutral P31213 H231R Disease Disease P31213 P181L Disease Disease P31213 A49T Neutral Neutral P31213 A207D Disease Disease P31213 R246W Disease Disease P31213 S245Y Disease Neutral P31213 E197D Disease Disease P31213 Q126R Disease Disease P31213 A228T Disease Disease P31213 R246Q Disease Disease P31213 G183S Disease Disease P31213 G85D Disease Neutral P31213 L224M Neutral Neutral P31213 G115D Disease Disease P31213 L55Q Disease Disease P31213 G158R Disease Disease P31213 G196S Disease Disease P31213 Y235F Disease Disease P31213 P212R Disease Neutral P31213 E200K Disease Disease P31213 V89L Neutral Neutral P31213 G123R Disease Disease Q96N66 V415L Neutral Neutral Q96N66 F261L Neutral Neutral P02545 G465D Disease Disease P02545 L140R Disease Disease P02545 R582H Disease Neutral P02545 R435C Disease Neutral P02545 E145K Disease Neutral P02545 E161K Disease Disease P02545 R190Q Disease Neutral P02545 R482L Disease Disease P02545 L248P Disease Disease P02545 R62G Disease Disease P02545 K97E Disease Neutral P02545 G608S Disease Neutral P02545 R482W Disease Neutral P02545 D192G Disease Neutral P02545 R624H Disease Neutral P02545 R399C Disease Neutral P02545 L35V Disease Disease P02545 R453W Disease Neutral P02545 R377L Disease Disease P02545 S573L Disease Neutral P02545 A57P Disease Disease P02545 K542N Disease Neutral P02545 L85R Disease Disease P02545 S143F Disease Neutral P02545 R527H Disease Neutral P02545 A43T Disease Disease P02545 E317K Disease Disease P02545 Y481H Disease Disease P02545 R133L Disease Disease P02545 R482Q Disease Neutral P02545 N195K Disease Neutral P02545 R527P Disease Disease P02545 R471C Disease Disease P02545 R527C Disease Disease P02545 L530P Disease Disease P02545 R541H Disease Disease P02545 R89L Disease Disease P02545 E203G Disease Disease P02545 E203K Disease Disease P02545 S143P Disease Disease P02545 R541S Disease Disease P02545 A529V Disease Neutral P02545 R133P Disease Disease P02545 L215P Disease Disease P02545 K486N Disease Disease P02545 Y267C Disease Disease P02545 D446V Disease Disease P02545 R298C Disease Neutral P02545 H222Y Neutral Neutral P02545 N456I Disease Disease P02545 R377H Disease Disease P02545 R28W Disease Disease P02545 R50S Disease Disease P02545 R60G Disease Disease P02545 R25P Disease Disease P02545 R25G Disease Disease P02545 T528R Disease Disease P02545 R349L Disease Neutral P02545 R190W Disease Disease P02545 D230N Disease Disease O00398 N3H Neutral Neutral Q9H788 E216G Neutral Neutral Q9H788 G263A Neutral Neutral Q7Z7G1 S65G Neutral Neutral Q9Y2H5 R837K Neutral Neutral Q9Y2H5 V43I Neutral Neutral A6QL63 G1076S Neutral Neutral A6QL63 A1002D Neutral Disease Q9NQI0 G148D Neutral Neutral O43929 L56V Neutral Neutral O43929 N78S Neutral Neutral P01225 C69G Disease Disease P01225 S20I Neutral Neutral P10071 C515G Disease Disease P10071 G727R Disease Disease P10071 C520Y Disease Disease P10071 I808M Disease Neutral P10071 A934P Disease Disease P10071 R625W Disease Neutral P10071 P707S Disease Neutral Q9NZJ6 G272S Neutral Neutral Q9NZJ6 H329Y Neutral Disease P16455 W65C Neutral Disease P16455 P58S Neutral Neutral P16455 E30K Neutral Neutral P16455 K178R Neutral Neutral P16455 E166D Neutral Disease P16455 L84F Neutral Neutral P16455 I143V Neutral Neutral P16455 G160R Neutral Disease Q9H501 I550T Neutral Neutral P46060 E133Q Neutral Neutral Q8WWB5 A117V Neutral Neutral Q9BV44 R459Q Neutral Neutral Q9Y3R5 G2139E Neutral Neutral Q9Y3R5 S1021W Neutral Neutral Q9Y3R5 R1217S Neutral Neutral Q9Y3R5 P1149H Neutral Neutral Q9Y3R5 G1118C Neutral Neutral Q6ZUT9 H487N Neutral Neutral Q6IQ26 Q224E Neutral Neutral Q6ZUT9 R52K Neutral Neutral Q9UM47 R153C Disease Neutral Q9UM47 R558C Disease Neutral Q9UM47 R728C Disease Neutral Q9UM47 C212S Disease Disease Q9UM47 V1183M Neutral Neutral Q9UM47 R141C Disease Neutral Q9UM47 P496L Neutral Neutral Q9UM47 V2223A Neutral Neutral Q9UM47 R182C Disease Neutral Q9UM47 C1261R Disease Disease Q9UM47 H1133Q Neutral Neutral Q9UM47 C222G Disease Neutral Q9UM47 C542Y Disease Disease Q9UM47 R578C Disease Neutral Q9UM47 C185R Disease Disease Q9UM47 G171C Disease Disease Q9UM47 C224Y Disease Disease Q9UM47 R1031C Disease Neutral Q9UM47 Y258C Disease Neutral Q9UM47 R110C Disease Disease Q9UM47 R133C Disease Disease Q9UM47 W71C Disease Neutral Q9UM47 R1231C Disease Disease Q9UM47 R1006C Disease Neutral Q9UM47 C146R Disease Disease Q9UM47 H170R Neutral Neutral Q9UM47 C49Y Disease Disease Q9UM47 R985C Disease Neutral Q9UM47 R169C Disease Neutral Q9UM47 R90C Disease Disease P28799 G515A Neutral Neutral Q9UI33 G481E Neutral Neutral Q9UI33 M777R Neutral Disease Q9UI33 Y1198H Neutral Neutral A6NMN3 R69L Neutral Neutral Q86YC2 I309V Neutral Neutral P11172 R96G Disease Disease P11172 S30G Neutral Disease P11172 V109G Disease Disease P11172 G213A Neutral Neutral P11172 G429R Disease Disease P11172 I446V Neutral Neutral Q8NHS0 M153L Neutral Neutral P48546 A207V Neutral Neutral P43220 G168S Neutral Disease P47871 G40S Neutral Neutral P48546 R136W Neutral Disease P47871 P114A Neutral Neutral P43220 P7L Neutral Neutral P43220 S333C Neutral Neutral P43220 R20K Neutral Neutral P47872 A122P Neutral Disease Q02643 L144H Disease Disease P43220 R131Q Neutral Neutral P43220 R421Q Neutral Neutral P48546 L262V Neutral Disease P43220 R44H Neutral Neutral Q02643 F242C Disease Disease P41587 R412H Neutral Neutral Q02643 A176V Disease Disease P43220 F260L Neutral Disease P48546 E354Q Neutral Neutral Q02643 A222E Disease Disease P32241 R445L Neutral Disease Q02643 K329E Disease Disease P47871 F303C Neutral Disease P41587 A39T Neutral Neutral P43220 A316T Neutral Neutral Q96AP4 N379D Neutral Neutral Q6PJG6 R20G Neutral Neutral Q8N816 I4M Neutral Neutral Q8N816 Y79H Neutral Neutral Q8N816 L95R Neutral Disease Q09666 Q3003K Neutral Neutral Q09666 A2114T Neutral Neutral Q09666 T5415A Neutral Neutral Q09666 M4611V Neutral Neutral Q09666 S3724P Neutral Neutral Q09666 G962V Neutral Disease Q09666 G4561D Neutral Neutral Q09666 I4613V Neutral Neutral Q09666 P2439L Neutral Disease Q09666 D4631G Neutral Neutral Q09666 V3190I Neutral Neutral Q49A26 N103D Neutral Neutral Q49A26 Y531C Neutral Disease Q49A26 Q459H Neutral Disease Q6IQ49 M312I Neutral Neutral Q92769 Y315H Neutral Disease Q92769 R230C Neutral Disease P32754 I267F Neutral Disease P32754 A33T Neutral Disease P32754 V340L Neutral Neutral P32754 I335M Disease Disease P32754 Y160C Disease Disease P32754 A268V Disease Disease Q96LW4 R168Q Neutral Neutral Q96LW4 T505K Neutral Neutral Q13557 Q463E Neutral Disease Q13557 D167E Neutral Neutral Q13557 T493I Neutral Neutral P41240 H442R Neutral Neutral P41240 G287D Neutral Neutral P41240 P45L Neutral Disease Q13882 A436T Neutral Neutral P41240 R398Q Neutral Disease Q6ZN30 T782A Neutral Neutral Q9P2H0 A178T Neutral Neutral Q9P2H0 I281T Neutral Neutral Q9P2H0 A302T Neutral Neutral Q9P2H0 C238G Neutral Neutral Q9P2H0 S275Y Neutral Neutral Q9P2H0 P710S Neutral Neutral Q9P2H0 M1021T Neutral Neutral Q9P2H0 N1077S Neutral Neutral Q5T8I9 T129A Neutral Neutral Q5T8I9 M361I Neutral Neutral Q5T8I9 R230Q Neutral Neutral P11310 C116Y Disease Disease P11310 C244R Disease Disease P16219 G209S Neutral Disease P11310 M149I Disease Neutral P11310 S336R Disease Disease Q9UKU7 R334C Disease Disease P16219 G92C Disease Disease P16219 R380W Disease Disease Q9UKU7 V203I Disease Neutral P16219 R46W Disease Disease P26440 G199V Disease Disease P16219 A192V Disease Disease P11310 G267R Disease Disease P26440 V371A Disease Neutral P26440 R50P Disease Disease P45954 S209G Neutral Disease P26440 L42P Disease Disease P11310 R206L Disease Neutral P11310 G310R Disease Disease P11310 T121I Disease Neutral P26440 D69N Disease Disease P28330 T303S Neutral Neutral P45954 L255F Disease Neutral P16219 R325W Disease Disease P11310 G195R Disease Disease P11310 M326T Disease Disease P26440 C357R Disease Disease P16219 G90S Disease Disease P16219 S353L Disease Disease P11310 T193A Disease Disease P26440 R392C Disease Disease Q9UKU7 R302Q Disease Disease Q9UKU7 A320T Disease Disease P11310 Y67H Disease Neutral Q9UKU7 Q385R Disease Neutral P16219 R171W Neutral Disease Q9UKU7 D134Y Disease Neutral P16219 W177R Disease Disease P11310 S245L Disease Disease P26440 R411L Disease Disease P11310 I375T Disease Disease P16219 R107C Disease Neutral Q9UKU7 M152T Disease Neutral P11310 R281T Disease Disease P11310 R53C Disease Neutral P11310 I78T Disease Neutral P16219 R383H Neutral Disease P11310 K329E Disease Neutral P16219 R383C Disease Disease P11310 Y352C Disease Neutral P26440 A311V Disease Disease P28330 Q333K Disease Neutral Q9UKU7 G137R Disease Disease Q9UKU7 M128I Disease Neutral O94983 S903P Neutral Neutral O94983 A267P Neutral Neutral Q15672 S188L Disease Disease Q15672 Q119P Disease Disease Q15672 L131P Disease Disease Q15672 A186T Disease Disease Q15672 I156V Disease Neutral Q15672 G84S Neutral Neutral Q15672 S31G Neutral Neutral Q15583 S157C Disease Neutral Q15583 T280A Disease Neutral Q15583 S291F Disease Neutral Q15583 P292L Neutral Neutral Q15583 P192R Disease Disease Q15583 Q236L Disease Neutral P15328 W160C Neutral Disease Q86TN4 R221C Neutral Neutral Q86TN4 F3L Neutral Neutral Q86TN4 H172R Neutral Neutral Q9NRQ2 S34N Neutral Neutral O15162 H262Y Neutral Disease Q9NRQ2 V155I Neutral Neutral Q9NRY6 I293V Neutral Neutral P26927 C13Y Neutral Neutral P14210 D330Y Neutral Disease P26927 C212F Neutral Disease P14210 S153I Neutral Disease P14210 E304K Neutral Disease P26927 E676K Neutral Disease P13796 D24E Neutral Neutral P13796 P544A Neutral Neutral P13796 E533K Neutral Neutral Q9BUB7 D259E Neutral Neutral Q9BUB7 T250A Neutral Neutral Q9BUB7 A34P Neutral Neutral Q9BUB7 N228K Neutral Neutral Q15942 H223L Neutral Neutral Q93052 Y346H Neutral Neutral Q96FB5 V400L Neutral Neutral Q9UKQ2 M765V Neutral Neutral Q8WW27 P275S Neutral Neutral Q8WW27 F271S Neutral Neutral Q8WW27 K331E Neutral Neutral Q8WW27 S75F Neutral Disease Q8WW27 V345M Neutral Neutral P15151 I340M Neutral Neutral P15151 A67T Neutral Neutral P28068 A162V Neutral Neutral P28068 A162E Neutral Neutral P28068 I197T Neutral Neutral P28068 S45F Neutral Disease P00813 A329V Disease Disease P00813 H15D Disease Disease P00813 R156C Disease Disease P00813 V129M Disease Disease P00813 R142Q Disease Neutral P00813 R101Q Disease Disease P00813 L152M Disease Neutral P00813 G20R Disease Disease P00813 P274L Disease Disease P00813 R149Q Disease Disease P00813 A179D Disease Disease P00813 K80R Neutral Neutral P00813 R76W Disease Disease P00813 G74C Disease Disease P00813 G216R Disease Disease P00813 R156H Disease Disease P00813 R211H Disease Neutral P00813 A215T Disease Disease P00813 A83D Disease Disease P00813 L304R Disease Disease P00813 T233I Disease Disease P00813 G140E Disease Disease P00813 S291L Disease Neutral P00813 L107P Disease Disease P00813 V177M Disease Disease P00813 Q199P Disease Neutral P00813 D8N Neutral Neutral P00813 R149W Disease Disease P00813 R101L Disease Disease P00813 R101W Disease Disease P00813 P297Q Disease Disease P00813 R211C Disease Disease Q7Z5L7 T444M Neutral Neutral Q7Z5L7 V472A Neutral Neutral O60296 V142I Neutral Neutral O60296 T528I Neutral Neutral O14896 R6C Disease Neutral O14896 L345P Disease Disease O14896 E349V Disease Disease O14896 S90G Disease Disease O14896 C347F Disease Neutral O14896 V18A Disease Disease O14896 K388E Disease Disease O14896 R45Q Disease Disease O14896 R84C Disease Disease O14896 N88H Disease Disease O14896 P396S Disease Disease O14896 V297I Disease Neutral O14896 V274I Neutral Neutral O14896 T100A Disease Disease O14896 V321M Disease Disease O14896 A2V Disease Neutral O14896 K320E Disease Disease O14896 R84H Disease Disease O14896 L251P Disease Disease O14896 R250Q Disease Disease O14896 A61G Disease Disease O14896 K66T Disease Disease O14896 V18M Disease Neutral O14896 T64I Disease Disease O14896 F369S Disease Disease O14896 L294P Disease Disease O14896 W60G Disease Disease O14896 K89E Disease Disease O14896 D98H Disease Disease O14896 G325E Disease Disease O14896 C374W Disease Disease O14896 P76S Disease Disease O14896 D430N Disease Neutral O14896 Q273R Disease Neutral O14896 G70R Disease Disease O14896 R400W Disease Disease O14896 L22P Disease Disease O14896 Q82K Disease Neutral O14896 R84G Disease Disease O14896 P39A Disease Disease O14896 A16V Disease Neutral P47211 P342L Neutral Neutral P47211 N334S Neutral Neutral P47211 C15W Neutral Neutral Q9UBX5 R351W Disease Neutral Q9UBX5 A363T Disease Disease Q9UBX5 S227P Disease Disease Q9UBX5 R71Q Disease Disease Q9UBX5 I169T Disease Neutral O95967 I259V Neutral Neutral Q9UBX5 V60L Disease Disease Q9UBX5 G412E Disease Disease Q9UBX5 P87S Disease Neutral O95967 E57K Disease Disease Q9UBX5 D364Y Neutral Disease P50135 T105I Neutral Neutral Q0D2K0 G235R Disease Disease Q0D2K0 S146F Disease Disease Q0D2K0 H175N Disease Disease Q6NVV3 I324V Neutral Neutral Q0D2K0 G80V Disease Disease Q0D2K0 A114D Disease Disease P10275 H874Y Disease Disease P10275 G683A Disease Neutral P10275 V715M Disease Neutral P10275 A645D Neutral Neutral P10275 C619Y Disease Disease P10275 Q798E Disease Disease P10275 S782N Disease Neutral P10275 S205R Neutral Neutral P10275 T755A Disease Neutral P10275 S791P Disease Disease P10275 Q64R Disease Neutral P10275 A586V Disease Disease P10275 L701H Disease Neutral P10275 L880Q Disease Disease P10275 V730M Disease Disease P10275 Q443R Neutral Disease P10275 A587S Disease Neutral P10275 K910R Disease Neutral P10275 S647N Disease Neutral P10275 I672T Disease Neutral P10275 R629Q Disease Disease P10275 R726L Disease Disease P10275 R608K Disease Disease P10275 Q919R Disease Neutral P10275 E793D Neutral Disease P10275 R607Q Disease Neutral P10275 L54S Disease Neutral P10275 V866M Disease Neutral P10275 F891L Disease Disease P10275 D890N Disease Neutral P10275 V757A Disease Neutral P10275 M266T Disease Disease P10275 A748T Disease Disease P10275 A721T Disease Neutral P10275 T877S Disease Neutral P10275 K180R Disease Neutral P10275 T877A Disease Disease P10275 K720E Disease Disease P10275 K717E Disease Neutral P10275 S759P Disease Disease P10275 K580R Disease Disease P10275 K630T Disease Neutral P10275 L744F Disease Disease P10275 R846G Disease Neutral P10275 M749I Disease Disease P10275 Y763C Disease Disease P10275 F754L Disease Neutral P10275 P269S Disease Neutral P10275 G909E Disease Disease P10275 Q112H Disease Neutral P10275 G750S Disease Neutral P10275 L574P Disease Disease P10275 A896T Disease Neutral P10275 L57Q Disease Neutral P10275 D528G Disease Neutral P10275 Q670R Disease Neutral P10275 Q902R Disease Disease P10275 G724D Disease Disease P10275 P340L Disease Neutral P10275 A748V Disease Disease P10275 L830P Disease Disease P10275 T575A Disease Neutral P09172 A318S Neutral Neutral P09172 D345N Disease Disease Q6UVY6 E488Q Neutral Neutral P09172 A211T Neutral Neutral P09172 E250Q Neutral Disease P09172 E181Q Neutral Neutral P09172 K239N Neutral Neutral P09172 R549C Neutral Neutral P09172 D290N Neutral Neutral P09172 L317P Neutral Disease Q6UVY6 K539E Neutral Neutral P09172 V101M Disease Disease P09172 D114E Disease Disease P36639 M124V Neutral Neutral Q9UPR3 N1004D Neutral Neutral Q7Z3E2 Q271K Neutral Neutral Q7Z3E2 T85I Neutral Neutral Q7Z3E2 R179Q Neutral Neutral Q96J92 D564A Disease Neutral Q96J92 R1185C Disease Neutral Q96J92 E562K Disease Disease Q96J92 Q565E Disease Neutral P09543 Q207R Neutral Neutral Q9Y3P4 T86M Neutral Disease Q86VV8 S1761F Neutral Neutral Q86VV8 S126A Neutral Neutral Q86VV8 K245R Neutral Neutral Q86VV8 H1742R Neutral Neutral P00441 D91A Disease Disease P00441 E22G Disease Neutral P00441 S135N Disease Disease P00441 D77Y Disease Disease P00441 G94R Disease Disease P00441 G94C Disease Disease P00441 E101G Disease Neutral P00441 L145F Disease Disease P00441 L107V Disease Disease P00441 N140K Disease Disease P00441 G94V Disease Disease P00441 A5S Disease Disease P00441 V149G Disease Disease P00441 L39R Disease Disease P00441 D125V Disease Disease P00441 G42S Disease Disease P00441 E22K Disease Neutral P00441 G86R Disease Disease P00441 I150T Disease Disease P00441 V15G Disease Disease P00441 D102N Disease Disease P00441 G17S Disease Disease P00441 G42D Disease Disease P00441 F46C Disease Disease P00441 L127S Disease Disease P00441 H49Q Disease Disease P00441 D91V Disease Disease P00441 R116G Disease Disease P00441 G109V Disease Disease P00441 A146T Disease Disease P00441 L39V Disease Disease P00441 I152T Disease Disease P00441 G94D Disease Disease P00441 L9V Disease Disease P00441 G38R Disease Disease P00441 A90V Disease Disease P00441 N87S Disease Disease P00441 H44R Disease Disease P00441 I113M Disease Disease P00441 V149I Disease Neutral P00441 E101K Disease Neutral P00441 G115A Disease Disease P00441 I105F Disease Disease P00441 D126H Disease Disease P00441 G73S Disease Disease P00441 D102G Disease Disease P00441 L145S Disease Disease P00441 E50K Disease Disease P00441 I113T Disease Disease P00441 L85F Disease Disease P00441 L9Q Disease Disease P00441 L85V Disease Disease P00441 V8E Disease Disease P00441 H47R Disease Disease P00441 H81A Disease Disease P00441 S106L Disease Neutral P00441 C7F Disease Disease P00441 A5V Disease Disease P00441 I114T Disease Disease P00441 G13R Disease Disease P00441 L68R Disease Disease P00441 G94A Disease Disease P00441 N66S Disease Disease P00441 V15M Disease Disease P00441 A5T Disease Disease P00441 C147R Disease Disease Q8WVV4 M349L Neutral Neutral Q8WVV4 E296A Neutral Neutral Q8WVV4 P207S Neutral Neutral Q8WVV4 C239S Neutral Neutral Q8WVV4 R329Q Disease Neutral Q8WVV4 C444Y Neutral Disease Q8WVV4 M323V Neutral Neutral Q8WVV4 Q434K Neutral Neutral P04637 C182S Disease Neutral P04637 R110L Disease Disease P04637 N247I Disease Disease P04637 C277G Disease Disease P04637 E286A Disease Disease P04637 P60S Disease Neutral P04637 E286K Disease Disease P04637 S166L Disease Neutral P04637 R156P Disease Disease P04637 N131K Disease Disease P04637 M160I Disease Disease P04637 P191T Disease Neutral P04637 M237I Disease Disease P04637 M133T Disease Neutral P04637 T170S Disease Disease P04637 D7H Disease Neutral P04637 R181L Disease Neutral P04637 G245C Disease Disease P04637 S240I Disease Disease P04637 V274F Disease Disease P04637 P153T Disease Neutral P04637 R248W Disease Disease P04637 R248Q Disease Disease P04637 D228E Disease Neutral P04637 V147G Disease Disease P04637 C141Y Disease Disease P04637 K132Q Disease Disease P04637 G154V Disease Disease P04637 L252P Disease Disease P04637 Q136K Disease Neutral P04637 R175P Disease Disease P04637 P152S Disease Disease P04637 A129D Disease Neutral P04637 L257P Disease Disease P04637 A307T Disease Neutral P04637 P177L Disease Disease P04637 R337C Disease Neutral P04637 L43S Disease Neutral P04637 V173M Disease Disease P04637 I254N Disease Disease P04637 G325V Disease Disease P04637 P152L Disease Disease P04637 Y220C Disease Disease P04637 E286D Disease Neutral P04637 D281G Disease Disease P04637 P278H Disease Disease P04637 F113C Disease Disease P04637 E286G Disease Disease P04637 P47S Neutral Neutral P04637 C176W Disease Disease P04637 Y234C Disease Disease P04637 M169T Disease Disease P04637 L194P Disease Disease P04637 R273G Disease Disease P04637 P151T Disease Disease P04637 Q192R Disease Neutral P04637 H193D Disease Disease P04637 I254T Disease Disease P04637 R280T Disease Disease P04637 G187S Disease Neutral P04637 V143A Disease Disease P04637 C238F Disease Disease P04637 C135S Disease Disease P04637 R273C Disease Disease P04637 D281E Disease Disease P04637 C141F Disease Disease P04637 V157D Disease Disease P04637 I195T Disease Disease P04637 R158C Disease Disease P04637 R248G Disease Disease P04637 L137Q Disease Disease P04637 I162V Disease Neutral P04637 M246T Disease Disease P04637 S241F Disease Disease P04637 P278S Disease Disease P04637 G245A Disease Disease P04637 G302V Disease Neutral P04637 C275W Disease Disease P04637 T284A Disease Neutral P04637 C238Y Disease Disease P04637 R175L Disease Disease P04637 E285K Disease Disease P04637 G187C Disease Disease P04637 P128S Disease Neutral P04637 C176F Disease Disease P04637 R158H Disease Disease P04637 V157F Disease Disease P04637 E198K Disease Disease P04637 V173E Disease Disease P04637 V172A Disease Disease P04637 K164N Disease Disease P04637 L130R Disease Disease P04637 P301L Disease Neutral P04637 P151S Disease Disease P04637 R213Q Disease Disease P04637 P278L Disease Disease P04637 M246V Disease Disease P04637 R174H Disease Disease P04637 I162S Disease Disease P04637 R110C Disease Disease P04637 Y205C Disease Disease P04637 S94T Disease Neutral P04637 R282W Disease Disease P04637 Y126D Disease Disease P04637 P300R Disease Neutral P04637 G245V Disease Disease P04637 R280I Disease Disease P04637 R249G Disease Disease P04637 S366A Neutral Neutral P04637 Q144P Disease Disease P04637 M246R Disease Disease P04637 Y220H Disease Disease P04637 S127F Disease Disease P04637 P72R Neutral Neutral P04637 R306Q Disease Disease P04637 G334V Disease Disease P04637 T230I Disease Disease P04637 L35F Disease Neutral P04637 C242F Disease Disease P04637 M169I Disease Neutral P04637 Y205D Disease Disease P04637 R273H Disease Disease P04637 P278T Disease Disease P04637 S149P Disease Disease P04637 Q165L Disease Neutral P04637 P309S Disease Neutral P04637 T155A Disease Neutral P04637 T125M Disease Disease P04637 A161S Disease Disease P04637 R158G Disease Disease P04637 P190L Disease Disease P04637 E258K Disease Disease P04637 V147D Disease Disease P04637 Y220S Disease Disease P04637 L145P Disease Disease P04637 R248L Disease Disease P04637 R175H Disease Disease P04637 L145Q Disease Disease P04637 H296P Disease Neutral P04637 G245S Disease Disease P04637 Q136E Disease Neutral P04637 C141G Disease Disease P04637 G245D Disease Disease P04637 C275Y Disease Disease P04637 E339K Neutral Disease P04637 Y163H Disease Disease P04637 T284P Disease Disease P04637 P278A Disease Disease P04637 N131S Disease Disease P04637 K132M Disease Disease P04637 R283C Disease Disease P04637 Q165R Disease Neutral P04637 L194R Disease Disease P04637 R110P Disease Disease P04637 E285Q Disease Disease P04637 R282L Disease Disease P04637 D281V Disease Disease P04637 V272L Disease Disease P04637 E286Q Disease Disease P04637 T170M Disease Neutral P04637 R337H Disease Disease P04637 V216M Disease Disease P04637 C135F Disease Disease P04637 V157I Disease Neutral P04637 G302E Disease Neutral P04637 R283H Disease Neutral P04637 E258D Disease Disease P04637 I232T Disease Disease P04637 D281H Disease Disease P04637 A138P Disease Disease P04637 G279E Disease Disease P04637 P151A Disease Disease P04637 R175C Disease Disease P04637 W53C Disease Disease P04637 R283G Disease Neutral P04637 R280K Disease Disease P04637 K139N Disease Disease P04637 E285V Disease Disease P04637 V173L Disease Disease P04637 R249S Disease Disease P04637 H168R Disease Disease P04637 R283P Disease Disease P04637 K292I Disease Disease P04637 Y126N Disease Disease P04637 K164Q Disease Disease P04637 I251N Disease Disease P04637 Y234H Disease Disease P04637 R175G Disease Disease P04637 A189P Disease Disease P04637 P87Q Disease Neutral P04637 D184Y Disease Disease P04637 D186Y Disease Disease P04637 D281A Disease Disease P04637 H193R Disease Disease P20827 D159V Neutral Neutral O95626 L46F Neutral Neutral Q8N8J7 P46Q Neutral Neutral Q9UP52 M172K Disease Disease Q9UP52 Q690P Disease Disease Q9UP52 I238M Neutral Neutral Q9UP52 V22I Disease Neutral Q9UP52 R455Q Neutral Disease Q9UP52 D230E Neutral Neutral Q9UP52 R752H Neutral Neutral P78549 R21W Neutral Neutral P78549 I176T Neutral Disease P78549 S234L Neutral Disease P78549 R33K Neutral Neutral P78549 D239Y Neutral Disease Q7Z3K3 E1365D Neutral Neutral P27986 M326I Neutral Neutral O00459 P313S Neutral Neutral P27986 E451K Neutral Neutral O00459 R234S Neutral Neutral P27986 R409Q Disease Disease Q96CB9 T51A Neutral Neutral Q96CB9 N128K Neutral Neutral Q96CB9 I325T Neutral Disease Q96CB9 I365V Neutral Neutral P01732 G111S Disease Disease Q8NDN9 A24V Neutral Neutral O95199 C515S Neutral Neutral O95199 A263T Neutral Neutral Q8NDN9 T500I Neutral Disease Q969Z0 P57L Neutral Neutral Q969Z0 A22S Neutral Neutral O95998 S195C Neutral Neutral O95998 R119Q Neutral Neutral P53999 S11G Neutral Neutral Q9Y5R6 S45T Neutral Neutral Q9Y5R6 R281S Neutral Neutral Q9Y5R6 P295L Neutral Disease Q9Y5R6 Y221S Neutral Disease Q9P2B2 V837I Neutral Neutral Q6FI81 A34E Neutral Neutral Q6FI81 Q52E Neutral Neutral Q9UQQ2 W262R Neutral Neutral O94769 Q56P Neutral Neutral O60921 S126G Neutral Neutral Q8NHY5 Q201R Neutral Neutral Q8NHY5 H130Q Neutral Disease Q8NHY5 Y268D Neutral Neutral O60921 Q147K Neutral Neutral O60921 D221E Neutral Neutral P47902 P130R Neutral Neutral Q13683 H695R Neutral Neutral Q8TCX1 F33S Neutral Neutral Q8TCX1 I230L Neutral Neutral Q8TCX1 P58S Neutral Neutral Q9H0N0 A159T Neutral Neutral Q9H497 F13L Neutral Neutral Q9P2D8 V1597A Neutral Neutral Q9P2D8 V1670I Neutral Neutral Q9P2D8 G2444S Neutral Neutral Q9P2D8 K2183R Neutral Neutral P57078 V463M Neutral Neutral P57078 N562Y Neutral Neutral P57078 P749S Neutral Neutral P57078 A12G Neutral Neutral P57078 I462N Neutral Disease P57078 S177N Neutral Neutral P57078 R669H Neutral Neutral Q96JF0 I341V Neutral Neutral Q96JF0 G154R Neutral Neutral Q9HCK4 A1236T Disease Neutral Q9HCK4 I945T Disease Neutral Q8WXI3 R453C Neutral Neutral Q9Y574 V17L Neutral Neutral P16871 I138V Disease Neutral P16871 E113D Neutral Neutral P16871 P132S Disease Neutral P16871 T66I Disease Neutral P16871 V356I Neutral Neutral Q9NQR4 V231A Neutral Disease Q9UBP0 N386S Disease Neutral Q9UBP0 R503W Disease Disease Q9UBP0 I344K Disease Disease Q9UBP0 W607C Disease Disease Q9UBP0 A556V Disease Disease Q9UBP0 D470V Disease Disease Q9UBP0 R562G Disease Disease Q9UBP0 R562Q Disease Disease Q9UBP0 R424G Disease Disease Q9UBP0 D493G Disease Disease Q9UBP0 C448Y Disease Disease Q9UBP0 T614I Disease Neutral Q9UBP0 S362C Disease Neutral Q9UBP0 R459G Disease Disease Q9UBP0 N386K Disease Neutral Q9UBP0 R499H Disease Disease Q9UBP0 E512D Disease Neutral Q9UBP0 S399L Disease Disease Q9UBP0 L195V Disease Neutral Q9UBP0 K388R Disease Disease Q9UBP0 D584H Disease Disease Q9UBP0 R503L Disease Disease Q9UBP0 L426V Disease Disease Q9UBP0 D555N Disease Disease Q9UBP0 L534P Disease Disease Q9UBP0 R499C Disease Disease Q9UBP0 P361L Disease Disease Q9UBP0 R460L Disease Disease Q9UBP0 A485V Disease Disease Q9UBP0 D441G Disease Disease Q9UBP0 P435L Disease Disease Q9UBP0 A551Y Disease Disease Q9UBP0 F381C Disease Disease Q9UBP0 P489L Disease Disease Q9UBP0 L378Q Disease Disease Q9UBP0 M390V Disease Disease Q9UBP0 Q347K Disease Neutral Q9UBP0 T615I Disease Neutral Q9UBP0 S436F Disease Neutral Q9UBP0 G370R Disease Disease Q9UBP0 S407R Disease Disease Q9UBP0 R460C Disease Disease Q9UBP0 G559D Disease Disease Q9UBP0 I406V Disease Neutral Q6UX71 I458V Neutral Neutral Q6UX71 V396I Neutral Neutral P43351 S287N Neutral Neutral P43351 R70W Neutral Disease P43351 Q221E Neutral Neutral P78333 A155V Neutral Neutral Q14088 M102T Neutral Neutral Q14190 L483M Neutral Neutral Q96JD4 C134S Neutral Neutral Q5VW36 I523V Neutral Neutral Q5VW36 V234I Neutral Neutral Q5VW36 T1373P Neutral Neutral Q5VW36 K1668E Neutral Neutral Q5VW36 L166S Neutral Neutral Q5VW36 T718S Neutral Neutral O43490 A31S Neutral Neutral O43490 A31G Neutral Neutral Q9NRA2 R39C Disease Disease Q9NRA2 H183R Disease Disease Q9NRA2 V296I Neutral Neutral Q9NRA2 P334R Disease Disease Q9NRA2 K136E Disease Disease Q9Y2C5 A372T Neutral Neutral Q9NRA2 G371V Disease Disease Q9BW04 N157T Neutral Neutral Q9BW04 T107A Neutral Neutral Q9BW04 R258G Neutral Neutral Q9BW04 P444S Neutral Neutral Q9BW04 P87S Neutral Neutral Q9BW04 N434S Neutral Neutral Q9BW04 F514S Neutral Neutral Q8N8D7 V140I Neutral Neutral Q86UY5 A237T Neutral Neutral Q93099 L25P Disease Disease Q93099 P230S Disease Disease Q93099 D153G Disease Disease Q93099 H371R Disease Disease Q93099 E42A Disease Disease Q93099 E168K Disease Disease Q93099 W97G Disease Disease Q93099 G161R Disease Disease Q93099 R225H Disease Disease Q93099 M368V Disease Disease Q93099 I216T Disease Disease Q93099 R330S Disease Disease Q93099 Y62C Disease Disease Q93099 F227S Disease Disease Q93099 D291E Disease Disease Q93099 V300G Disease Disease Q93099 S189I Disease Neutral Q93099 W60G Disease Disease Q93099 A122D Disease Disease Q93099 P230T Disease Disease Q93099 G270R Disease Disease Q9HAZ2 P633L Neutral Neutral Q9HAZ2 P533S Neutral Neutral Q8WTT2 P194L Neutral Neutral Q8WTT2 E472A Neutral Neutral Q8IZ83 V227L Neutral Disease Q8IZ83 E110K Neutral Neutral P02489 R116C Disease Disease P02511 S41Y Neutral Neutral P02511 P51L Neutral Disease P02511 R120G Disease Disease Q92466 M215T Neutral Neutral Q92466 K244E Disease Neutral Q92466 R273H Disease Disease Q92466 A293T Neutral Neutral Q8IVB4 I589V Neutral Neutral Q9NPA5 F425Y Neutral Neutral Q9NPA5 Q68P Neutral Neutral Q9NPA5 S451N Neutral Neutral Q9NPA5 P139L Neutral Neutral Q9NPA1 N165S Neutral Neutral Q9NPA1 M230T Neutral Disease Q9NPA1 D44G Neutral Neutral Q9NPA1 A53T Neutral Neutral Q9NPA1 L75V Neutral Neutral Q9H2E6 D567E Neutral Disease Q9H2E6 R559H Neutral Neutral Q9H2E6 H518Y Neutral Neutral Q99592 E132G Neutral Neutral Q68DA7 L686P Neutral Neutral O15218 C349R Neutral Neutral Q8TF63 T75P Neutral Neutral Q8TF63 N97D Neutral Neutral Q8N0U4 G60A Neutral Neutral Q14527 R819H Neutral Neutral Q7Z2K6 S44N Neutral Neutral O15453 Q102E Neutral Neutral Q8N5C7 L9P Neutral Neutral Q8N5C7 S25P Neutral Neutral Q8N5C7 E13K Neutral Neutral Q9H8M1 L48F Neutral Neutral Q86YD3 Q342R Neutral Neutral Q86YD3 W25C Neutral Disease Q9HCM1 V1226I Neutral Neutral Q9HCM1 S1208C Neutral Neutral Q9HCM1 S352G Neutral Neutral Q9HCM1 F954S Neutral Neutral Q9HCM1 S433T Neutral Neutral Q9HCM1 R309Q Neutral Neutral Q9HCM1 I59V Neutral Neutral Q9HCM1 S346N Neutral Neutral Q9HCM1 I202V Neutral Neutral Q9HCM1 H106Q Neutral Neutral Q9HCM1 P518S Neutral Neutral Q9HCM1 P250L Neutral Neutral Q9HCM1 T1338A Neutral Neutral Q9HCM1 T1010K Neutral Neutral Q53H96 N150K Neutral Neutral Q53H96 V105M Neutral Disease Q53H96 R57Q Neutral Neutral Q00266 R199C Disease Disease Q00266 R356Q Disease Disease Q00266 E344A Disease Disease Q00266 P357L Disease Disease Q00266 G378S Disease Disease Q00266 S38N Disease Disease Q00266 Q119H Neutral Neutral Q00266 G336R Disease Disease Q00266 R264C Disease Disease Q00266 R264H Disease Disease Q00266 I322M Disease Disease Q00266 A55D Disease Disease Q00266 L305P Disease Disease Q7Z3V4 Q346R Neutral Neutral Q5JRA6 G1659C Neutral Disease Q5JRA6 E881G Neutral Neutral Q5JRA6 K605R Neutral Neutral Q5JRA6 K1723E Neutral Neutral Q5JRA6 K482E Neutral Neutral Q96RW7 H4084Y Neutral Neutral Q96RW7 I2418T Neutral Disease Q96RW7 M2327I Neutral Neutral Q96RW7 D5087V Neutral Disease Q96RW7 A4720T Neutral Neutral Q96RW7 A1624V Neutral Disease Q96RW7 E2893G Neutral Neutral Q96RW7 Q5345R Disease Neutral P50914 A138S Neutral Neutral Q969R5 I7V Neutral Neutral Q969R5 R300W Neutral Neutral P15812 L184P Neutral Disease P29017 F300S Neutral Neutral P06126 I30T Neutral Disease P15812 R154W Neutral Disease P29017 N70T Neutral Disease P15812 Q96R Neutral Neutral P15813 T64S Neutral Disease P06126 W68C Neutral Disease Q9NVS9 R116Q Neutral Neutral Q9NVS9 E50K Neutral Disease Q9NVS9 R229W Disease Disease Q13394 S70P Neutral Disease Q5T4I8 A13D Neutral Neutral Q96KD3 E242K Neutral Neutral Q96KD3 S228L Neutral Neutral Q9NQ76 V330I Neutral Neutral Q01113 Y288C Neutral Disease Q01113 R63K Neutral Neutral Q01113 E239Q Neutral Neutral P53701 R217C Disease Disease Q96HA7 A714V Neutral Neutral Q96HA7 G493S Neutral Disease Q96HA7 V488M Neutral Disease Q96HA7 P1276L Neutral Neutral Q9BWU0 P139T Neutral Neutral Q96N76 S311T Neutral Disease Q96N76 R188W Neutral Neutral Q86VD7 L312M Neutral Neutral Q86VD7 S39P Neutral Disease Q9BXB5 N254D Neutral Neutral P46019 R186C Disease Disease P46019 R186H Disease Disease P46020 D299V Disease Disease P46019 T1114I Disease Disease P46019 G1207W Disease Disease P46019 K189E Disease Disease P46019 E38Q Neutral Neutral P46019 P399S Disease Disease P46019 E1125K Disease Disease P46019 H132P Disease Disease P46019 R295H Disease Disease P46019 H132Y Disease Disease P46019 P1205L Disease Disease P46019 G193V Disease Disease P46019 D299G Disease Disease P19447 T119P Disease Disease P19447 F99S Disease Disease P19447 K117R Neutral Neutral P19447 S735P Neutral Neutral P19447 G402C Neutral Neutral P19447 S704L Neutral Neutral Q6P5Z2 A180E Neutral Neutral Q8NCW5 V19L Neutral Neutral Q96MT8 S651L Neutral Neutral Q9NQ55 G358V Neutral Neutral Q9UHD0 F175S Neutral Neutral Q99684 K403R Disease Neutral Q99684 N382S Disease Neutral Q86WP2 R122G Neutral Neutral Q9HC44 R439H Neutral Neutral Q9HC44 P192S Neutral Neutral Q96S06 P562R Neutral Neutral Q96S06 S203P Neutral Neutral Q14244 R526P Neutral Neutral Q14244 V361I Neutral Neutral Q14244 R558W Neutral Neutral P07858 L26V Neutral Disease P07858 S235N Neutral Neutral Q76EJ3 A184S Neutral Disease Q6ZVN6 S53I Neutral Neutral P35354 V511A Neutral Neutral P23219 V481I Neutral Neutral P35354 P428A Neutral Neutral P23219 I443V Neutral Neutral P23219 R53H Neutral Neutral P23219 R149L Neutral Disease P35354 G587R Neutral Neutral P23219 K359R Neutral Disease P35354 E488G Neutral Disease P35354 R228H Neutral Neutral P23219 P17L Neutral Neutral P23219 L237M Neutral Neutral P23219 R8W Neutral Neutral O43597 P106S Neutral Neutral P55103 R322Q Neutral Neutral P34741 A59T Neutral Neutral P34741 S71T Neutral Neutral Q6P050 V109L Neutral Disease Q96PP9 Y541N Neutral Neutral P32455 I78V Neutral Neutral Q96PP9 K125E Neutral Disease Q96PP9 M545L Neutral Neutral Q6ZN66 M355V Neutral Neutral Q96PP9 M545I Neutral Neutral P32455 S349T Neutral Neutral Q96PP9 E546K Neutral Neutral Q8N8V2 I14T Neutral Disease Q96PP8 T35M Neutral Neutral Q9H0R5 C459R Neutral Neutral Q9H0R5 V437M Neutral Neutral Q96PP9 E551G Neutral Neutral Q9H0R5 V526A Neutral Neutral Q6ZN66 D520V Neutral Neutral Q96PP9 L549M Neutral Neutral Q6ZN66 A331S Neutral Neutral Q8N8V2 G618R Neutral Disease Q6ZN66 L344F Neutral Neutral Q96PP9 E551K Neutral Neutral P32455 E166D Neutral Neutral Q6ZN66 T278I Neutral Neutral Q96PP9 M542I Neutral Neutral Q96PP9 I379V Neutral Neutral Q9UBC0 P75A Neutral Neutral P55318 G91R Neutral Neutral P51811 E327K Disease Disease P51811 R222G Disease Disease P51811 C294R Disease Disease Q9HAV4 K610N Neutral Neutral Q86WH2 R232H Neutral Neutral Q96A29 R147C Disease Disease Q96A29 T308R Disease Disease Q6ZRP7 K126E Neutral Neutral Q9UMZ3 I1734T Neutral Neutral Q9UMZ3 T1040I Neutral Disease Q9UMZ3 A1120P Neutral Disease Q9UMZ3 N1244D Neutral Neutral Q9UMZ3 R2121K Neutral Disease Q9UMZ3 F1098L Neutral Neutral P07864 E285Q Neutral Neutral P00338 K222E Neutral Neutral Q96LP6 D11E Neutral Neutral Q96LP6 P182R Neutral Neutral Q13424 L364F Neutral Neutral Q13425 D424E Neutral Neutral Q86UG4 T654R Neutral Neutral Q86UG4 A27V Neutral Neutral Q86UG4 K381R Neutral Neutral Q96GX5 V610I Neutral Neutral Q96GX5 E167D Disease Neutral Q96GX5 T337K Neutral Neutral Q96GX5 P620A Neutral Neutral P10997 S53G Neutral Neutral Q6UWH4 G432S Neutral Disease Q08462 V147L Neutral Neutral Q9UKF2 L359P Neutral Disease Q96M78 S92L Neutral Neutral Q9Y6Q9 G460R Neutral Neutral Q15596 M1282I Neutral Neutral Q9Y6Q9 Q586H Neutral Neutral Q9Y6Q9 P559S Neutral Neutral Q7Z3B3 P1010L Neutral Neutral P48637 K437E Neutral Neutral P48637 A26D Disease Disease P48637 R236Q Neutral Disease P48637 D469E Disease Disease P48637 Y270H Disease Disease P48637 L188P Disease Disease P48637 G464V Disease Disease P48637 R283C Disease Disease P48637 L286Q Disease Disease P48637 Y270C Disease Disease P48637 D219A Disease Disease P48637 D219G Disease Disease P48637 R267W Disease Disease P48637 L254R Disease Disease P48637 R330C Disease Disease P49908 P112S Neutral Neutral P49908 A234T Neutral Neutral P49908 S314P Neutral Neutral P49908 R368C Neutral Neutral P49908 R278Q Neutral Neutral O75908 E14G Neutral Neutral O75908 T254I Neutral Neutral Q8N9P6 L5P Neutral Neutral Q15878 D858E Neutral Neutral Q8IUS5 Y321F Neutral Neutral P07358 R117G Neutral Disease P07358 E108K Neutral Disease P07358 P261L Neutral Neutral Q96DD0 I121L Neutral Neutral Q15437 P433L Neutral Neutral Q15436 L211V Neutral Neutral Q15437 H489Q Neutral Disease Q15436 F382L Disease Disease Q86SG4 C91R Neutral Neutral Q15046 T595S Neutral Neutral P18206 V234L Neutral Neutral P18206 L277M Disease Neutral P18206 R975W Disease Neutral P18206 A934V Neutral Neutral P18206 P943A Neutral Neutral P60201 D203E Disease Disease P60201 A242P Disease Disease P60201 S226P Disease Disease P60201 R205G Disease Disease P60201 V172A Disease Neutral P60201 C220Y Disease Disease P60201 C228Y Disease Disease P60201 G217S Disease Disease P60201 G74R Disease Disease P60201 W181C Disease Disease P60201 D203V Disease Disease P60201 H130Y Disease Neutral P60201 L46R Disease Disease P60201 L210H Disease Neutral P60201 S253F Disease Disease P60201 Q234P Disease Disease P60201 W163R Disease Disease P60201 F51S Disease Disease P60201 D203N Disease Disease P60201 G246E Disease Disease P60201 A249P Disease Disease P60201 P216S Disease Disease P60201 T182P Disease Disease P60201 I187T Disease Neutral P60201 T116K Disease Neutral P60201 F32V Disease Disease P60201 L31P Disease Disease P60201 K151N Disease Disease P60201 P15L Disease Disease P60201 C35Y Disease Disease P60201 T156I Disease Disease P60201 L224P Disease Disease P60201 D203G Disease Disease P60201 H148Y Disease Neutral P60201 A248E Disease Neutral P60201 A39T Disease Disease P60201 Y60C Disease Neutral P60201 C169R Disease Disease P60201 D203H Disease Disease P60201 P211L Disease Disease P60201 T43I Disease Disease P60201 V166E Disease Disease P60201 F32L Disease Disease P60201 F237S Disease Disease P60201 Y175C Disease Disease P60201 G221C Disease Disease P60201 P216A Disease Disease P60201 V209D Disease Disease P60201 H140Y Disease Neutral P60201 S170F Disease Disease P60201 T183N Disease Disease P60201 Y207C Disease Disease P60201 V219F Disease Neutral P60201 W212R Disease Disease Q96HP4 R82C Neutral Neutral Q96HP4 S64A Neutral Neutral Q96HP4 R59Q Neutral Disease P12883 S532P Disease Disease P12883 L908V Disease Neutral P12883 M349T Disease Disease P12883 A728V Disease Neutral P12883 L1706P Disease Disease Q7Z406 N1559S Neutral Neutral P35579 I1816V Disease Neutral P12883 R870C Disease Disease P12883 S642L Disease Neutral P35579 R1165C Disease Disease P12883 D928N Disease Neutral Q9UKX3 E1076D Neutral Neutral P12883 G741R Disease Disease P12883 R1845W Disease Disease P12883 D3A Neutral Disease P12883 R249Q Disease Disease P12883 V824I Disease Neutral Q9UKX3 G701R Neutral Disease P12883 I736T Disease Neutral P12883 D778E Disease Disease Q9UKX3 M1071V Neutral Neutral P12883 G768R Disease Disease Q9Y623 E1911K Neutral Disease P12883 R870H Disease Disease P12883 R712L Disease Disease P13535 R674Q Disease Disease P12883 A355T Disease Disease P12883 P731L Disease Disease P12883 G741W Disease Disease P35579 R1165L Disease Neutral P11055 E375K Disease Neutral P12883 R1500P Disease Disease P12883 R719W Disease Disease P11055 S261F Disease Disease P12883 A430E Disease Disease P12883 E949K Disease Neutral P13533 T1737S Neutral Neutral P12883 M877K Disease Neutral P13535 E1261G Neutral Neutral P12883 K615N Disease Disease P12883 E846Q Disease Neutral P12883 V39M Disease Disease Q9UKX3 R1294Q Neutral Neutral P12883 L517M Disease Disease P12883 N696S Disease Neutral P12883 R663S Disease Neutral P11055 G769V Disease Disease P12883 V406M Disease Neutral P35579 R702C Disease Disease P11055 D517Y Disease Disease P12883 L390V Disease Neutral Q9UKX3 R1862H Neutral Disease P11055 D1622A Disease Neutral P12883 R143W Disease Neutral P35579 A95T Disease Disease P12883 A797T Disease Disease P12883 E466Q Neutral Disease P13533 L783M Neutral Neutral P12883 T188N Disease Disease P13533 A1101V Neutral Neutral P12883 E1218Q Disease Neutral P12883 R671C Disease Disease Q7Z406 I266V Neutral Neutral P12883 F513C Disease Disease P11055 S292C Disease Neutral P12883 R869C Disease Disease P12883 L1135R Disease Neutral P12883 L601V Disease Disease P12883 F244L Disease Disease P11055 R672H Disease Disease P35579 K373N Disease Disease P12883 M852T Disease Neutral P12883 R694C Disease Disease P11055 A1637V Disease Neutral Q9UKX2 L1061V Neutral Neutral Q9Y2K3 R454Q Neutral Disease P12883 Q734E Disease Neutral P12883 R453C Disease Disease P12883 D587V Disease Disease P12883 R190T Disease Neutral P12883 I443T Disease Disease P13533 Q88E Neutral Neutral P12883 G584R Disease Disease Q7Z406 L976F Disease Disease P12883 R719Q Disease Disease P12883 E924K Disease Disease P12883 T1377M Disease Neutral P12883 E1555K Disease Disease P11055 R1137C Neutral Disease P12883 R204H Disease Neutral P12883 C905F Disease Disease P12883 L796F Disease Neutral P12883 T124I Disease Disease P12883 R403L Disease Disease P12883 E935K Disease Disease P12883 D107E Neutral Neutral P12883 G256E Disease Disease P12883 V411I Disease Neutral P35579 N93K Disease Disease Q9UKX2 E706K Disease Disease P12883 G733E Disease Disease P11055 Y583S Disease Disease P12883 R1382W Disease Disease P12883 R403W Disease Disease P12883 N479S Disease Disease P11055 T178I Disease Disease P35579 D1424H Disease Neutral P12883 V1692M Neutral Disease P12883 I263T Disease Disease P35749 V1289A Neutral Neutral P13533 I820N Disease Disease P35579 T1155I Disease Neutral P11055 R672C Disease Disease P12883 Y162C Disease Disease P12883 M659I Disease Disease P12883 S1776G Disease Neutral P12883 R723G Disease Neutral Q9Y2K3 T949I Neutral Neutral P12883 M515V Disease Disease P12883 R403Q Disease Neutral P12883 R858C Disease Disease P12883 A428V Disease Disease P12883 D778G Disease Disease P12883 V59I Disease Neutral P12883 Q595R Disease Disease P12883 R143Q Disease Neutral Q9Y623 A594T Neutral Neutral P13535 E924G Neutral Disease Q7Z406 S120L Disease Disease P12883 E743D Disease Neutral P13533 R795Q Disease Disease Q9Y623 M1106I Neutral Neutral P35579 E1841K Disease Disease P12883 R869G Disease Neutral Q9Y623 K1209E Neutral Neutral Q7Z406 G376C Disease Disease P11055 E498G Disease Disease P35579 R702H Disease Disease Q9UKX2 R1927Q Neutral Disease P12883 S1491C Neutral Neutral P12883 N232S Disease Disease P12883 R787H Disease Disease P12883 A1663P Disease Neutral Q9Y623 G1802D Neutral Neutral P12883 E483K Disease Disease P35579 D1424N Disease Neutral P12883 G716R Disease Neutral P12883 R694H Disease Disease P12883 V606M Disease Neutral P35749 V1310M Neutral Neutral P12883 R723C Disease Disease P35749 A1234T Neutral Neutral Q9Y623 A1117D Neutral Neutral P35579 S96L Disease Disease Q7Z406 R726S Disease Disease P12883 Q222K Disease Disease P11055 K838E Disease Disease P12883 A1379T Disease Neutral P12883 F764L Disease Disease Q9Y2K3 T1125A Neutral Neutral P12883 G584S Disease Disease P12883 N187K Disease Disease P35579 D1424Y Disease Neutral P12883 N602S Disease Neutral P12883 A26V Disease Disease Q9Y2K3 Y504H Neutral Neutral P12883 R663H Disease Disease P12883 V320M Disease Neutral P12883 A223T Disease Disease P12883 I736M Disease Neutral P12883 E924Q Disease Neutral P12883 A1777T Disease Neutral P12883 S782N Disease Neutral P35579 R705H Disease Disease P11055 V825D Disease Disease P12883 A1124S Neutral Neutral P35579 S1114P Disease Disease P12883 E499K Disease Disease P11055 T1192A Neutral Neutral Q9Y623 T883M Neutral Neutral P13535 W1692R Neutral Neutral P12883 E930K Disease Disease P35749 R1758Q Disease Neutral P51659 R106H Neutral Disease P51659 I559V Neutral Neutral P51659 G16S Disease Disease P51659 W511R Neutral Neutral P51659 T292S Neutral Neutral Q96ED9 G10R Neutral Neutral Q96ED9 H488Q Neutral Neutral Q5MY95 L62P Neutral Neutral P49961 V293I Neutral Neutral O76003 P123S Neutral Neutral O76003 Q21H Neutral Neutral Q10472 Y414D Neutral Disease Q9UKN7 Q2716H Disease Disease Q9UKN7 N2111Y Disease Disease Q9UKN7 Y2682F Neutral Neutral Q9UKN7 I2113F Disease Disease Q9UKN7 A2490T Neutral Neutral Q9UKN7 C1977R Neutral Disease Q9UKN7 G2018R Neutral Neutral Q8IV76 Q213E Neutral Neutral Q8WUJ3 V1109I Neutral Neutral Q8WUJ3 H783Y Disease Neutral Q8WUJ3 H783R Neutral Neutral Q8WUJ3 P1169A Neutral Neutral Q8WUJ3 R187H Disease Disease Q8WUJ3 R187C Disease Disease Q9H6F5 Q153H Neutral Neutral Q96C11 L134V Neutral Disease Q96NT5 G147R Disease Disease Q96NT5 R376W Disease Disease Q96NT5 P425R Disease Neutral Q96NT5 R113S Disease Disease Q96NT5 S318R Disease Disease Q14623 E131K Disease Disease Q14623 D100N Disease Disease Q14623 E95K Disease Disease Q14623 D100E Disease Disease Q14623 V190A Disease Neutral Q14623 P46L Disease Disease Q14627 W111R Neutral Neutral Q6ZNA4 K9N Neutral Neutral Q9NQT4 T5M Neutral Neutral P17050 R329Q Disease Disease P17050 R329W Disease Disease P17050 S160C Disease Neutral P17050 E325K Disease Disease O96007 E168K Disease Disease Q6P1W5 Q45E Neutral Neutral Q6P1W5 D112E Neutral Neutral Q86VW2 G397R Neutral Disease Q86VW2 Q506R Neutral Neutral Q86VW2 C253Y Neutral Disease Q96F10 R126C Neutral Disease Q52M58 V33A Neutral Neutral Q52M58 R3W Neutral Neutral Q9BZJ0 G35R Neutral Neutral Q8TAS1 Y197D Neutral Disease Q8TAS1 L159V Neutral Disease Q6ZP01 D52H Neutral Neutral Q6ZP01 N892H Neutral Neutral P40938 L16V Neutral Neutral Q9UHK0 S36R Neutral Neutral Q9NXB9 V225M Neutral Neutral Q9NXB9 T216A Neutral Neutral Q5TCX8 E563D Neutral Neutral Q5TCX8 P982L Neutral Neutral Q5TCX8 V728I Neutral Neutral Q5TCX8 S597F Neutral Disease Q5TCX8 R977C Neutral Neutral Q5TCX8 E741D Neutral Neutral Q5TCX8 T900I Neutral Neutral Q5TCX8 C784G Neutral Neutral Q5TCX8 R892W Neutral Disease Q5TCX8 D420N Neutral Neutral Q3SXZ7 Y58C Neutral Disease Q00604 R74C Disease Neutral Q00604 A63D Disease Disease Q00604 K58N Disease Neutral Q00604 I123N Disease Disease Q00604 C69S Disease Neutral Q00604 S101F Disease Neutral Q00604 C65Y Disease Neutral Q00604 A105T Disease Neutral Q00604 Y120C Disease Disease Q00604 R41K Disease Neutral Q00604 C96Y Disease Neutral Q00604 K104Q Disease Neutral Q00604 H42R Disease Neutral Q00604 S75P Disease Neutral Q00604 D23E Neutral Neutral Q00604 V60E Disease Disease Q00604 L61P Disease Disease Q00604 Y44C Disease Neutral Q00604 L124F Disease Neutral Q00604 L16P Disease Disease Q00604 R90P Disease Neutral Q00604 S75C Disease Neutral Q00604 C39R Disease Disease Q00604 C96W Disease Disease Q00604 R121Q Disease Disease Q00604 C65W Disease Neutral Q00604 L61F Disease Neutral Q00604 L13R Disease Disease Q00604 C110G Disease Neutral Q00604 R121G Disease Disease Q00604 R121W Disease Disease P05129 G128D Disease Disease P05129 R141C Neutral Disease P05129 H101Y Disease Disease P05129 R659S Neutral Neutral P05129 H415Q Neutral Neutral P05129 S119P Disease Disease P05129 A523D Neutral Disease P00450 R367C Neutral Disease P00450 T841R Neutral Neutral P00450 D544E Neutral Disease P00450 R793H Neutral Neutral P00450 P477L Neutral Disease P00450 T551I Neutral Disease Q15831 W239C Disease Disease Q15831 G135R Disease Disease Q15831 D194N Disease Disease Q15831 D194Y Disease Disease Q15831 L67P Disease Disease Q15831 Y49D Disease Disease Q15831 G163D Disease Disease Q15831 R297K Disease Disease Q15831 P315S Disease Neutral Q8TEX9 P580A Neutral Neutral Q8TEX9 A513V Neutral Neutral Q6PEY1 L44F Neutral Neutral Q9BZS1 I363V Disease Neutral Q9BZS1 R397W Disease Disease Q9BZS1 A384T Disease Disease Q9BZS1 F371C Disease Disease Q96A26 A50V Neutral Neutral Q14667 H986Q Neutral Neutral Q14667 V1516G Neutral Neutral O94779 M1094V Neutral Neutral O94779 S23A Neutral Neutral O94779 I530V Neutral Neutral Q02246 R657W Neutral Neutral Q02246 A145T Neutral Disease O94779 N81S Neutral Neutral O94779 Y1065F Neutral Neutral O94779 S1079T Neutral Neutral Q9P232 S630N Neutral Disease Q02246 P366L Neutral Neutral O94779 L70R Neutral Neutral P51587 T582P Neutral Neutral P51587 E1593D Neutral Neutral P51587 I3103M Disease Neutral P51587 N1805S Neutral Neutral P51587 R118H Disease Neutral P51587 S976F Neutral Neutral P51587 N1279S Neutral Neutral P51587 D2723H Disease Disease P51587 N1880K Neutral Neutral P51587 N1730Y Disease Neutral P51587 N2706S Neutral Neutral P51587 L2510P Disease Disease P51587 E1901K Disease Neutral P51587 C1580Y Disease Neutral P51587 K2729N Disease Neutral P51587 Y2222C Disease Neutral P51587 A2466V Neutral Neutral P51587 T598A Neutral Neutral P51587 A2951T Neutral Neutral P51587 T2515I Disease Neutral P51587 K2128N Disease Neutral P51587 N1147S Neutral Neutral P51587 G3076E Neutral Disease P51587 T630I Disease Neutral P51587 E2275G Disease Neutral P51587 K2950N Disease Neutral P51587 T1915M Neutral Neutral P51587 N886I Neutral Neutral P51587 D1513N Neutral Neutral P51587 H2440R Neutral Neutral P51587 V3244I Neutral Neutral P51587 T431I Disease Neutral P51587 F81L Disease Neutral P51587 C554W Disease Neutral P51587 K2162R Neutral Neutral P51587 T3374I Neutral Neutral P51587 I505T Disease Neutral P51587 H372N Neutral Neutral P51587 R3276S Neutral Neutral P51587 T1414M Neutral Neutral P51587 V2969M Neutral Neutral P51587 N991D Neutral Neutral P51587 I1929V Disease Neutral P51587 N108H Neutral Neutral P51587 E462G Disease Neutral P51587 K1445T Disease Neutral P51587 D728A Disease Neutral P51587 G2353R Disease Neutral P51587 L613R Disease Neutral P51587 K1690N Disease Neutral P51587 S599F Neutral Neutral P51587 P3300S Disease Neutral P51587 I729M Disease Neutral P51587 Y42C Disease Neutral P51587 N3124I Disease Neutral P51587 T2722R Disease Disease P51587 G25R Disease Neutral P51587 M3118T Disease Neutral P51587 S1172L Disease Neutral P51587 T64I Disease Neutral P51587 T1887M Disease Neutral P51587 S326R Disease Neutral P51587 F2293L Disease Neutral P51587 R2502H Disease Neutral P51587 M784V Neutral Neutral P51587 R2488K Disease Neutral P51587 K327E Disease Neutral P51587 G1771D Disease Neutral P51587 Y2094C Disease Neutral P51587 P222S Disease Neutral P51587 V2138F Neutral Neutral P51587 W31C Disease Neutral P51587 V1804A Disease Neutral P51587 A75P Disease Neutral P51587 V2728I Disease Neutral P51587 P201R Disease Neutral P51587 I2490T Neutral Neutral P51587 G1529R Disease Neutral P51587 R2034C Neutral Neutral P51587 R2108C Neutral Neutral P51587 W2626C Disease Disease P51587 P2096L Disease Neutral P51587 L929S Neutral Neutral P51587 V1988I Disease Neutral P51587 R448H Disease Neutral P51587 K3257R Neutral Neutral P51587 F32L Disease Neutral P51587 G2274V Disease Neutral P51587 V2118L Disease Neutral P51587 H2074N Neutral Neutral P51587 Y3098H Disease Neutral P51587 R2787H Disease Neutral P51587 S2072C Disease Neutral P51587 G2793R Disease Disease P51587 W31R Disease Disease P51587 D707Y Neutral Neutral P51587 N987I Neutral Neutral P51587 D1420Y Neutral Neutral P51587 K3196E Disease Neutral P51587 D935N Disease Neutral P51587 K53R Disease Neutral P51587 C315S Disease Neutral P51587 E1036K Disease Neutral P51587 T2031A Disease Neutral P51587 L2480V Neutral Neutral P51587 F1524V Disease Neutral P51587 R2336H Disease Neutral P51587 T3013I Disease Neutral P51587 V355L Disease Neutral P51587 C1290Y Neutral Neutral P51587 V211A Disease Neutral P51587 D3095E Neutral Disease P51587 M192T Disease Neutral P51587 S2835P Neutral Neutral P51587 T1679I Disease Neutral P51587 I2944F Neutral Neutral P51587 N2135H Disease Neutral P51587 K322Q Neutral Neutral P51587 Q2421H Disease Neutral P51587 I3412V Neutral Neutral P51587 S1106R Disease Neutral P51587 H2415N Disease Neutral P51587 P3063S Disease Neutral P51587 N60S Disease Neutral P51587 E2089D Disease Neutral P51587 Q2456E Disease Neutral P51587 T3357R Disease Neutral P51587 H1561N Neutral Neutral P51587 G405R Disease Neutral P51587 D1902N Neutral Neutral P51587 S1179N Disease Neutral P51587 N289H Neutral Neutral P51587 E2856A Neutral Neutral P51587 R2842C Disease Disease O00222 R392Q Neutral Neutral O00222 S10C Neutral Neutral O00222 F21C Neutral Disease Q14831 Y433F Neutral Neutral O15303 G150S Disease Disease O00222 V548G Neutral Neutral Q14833 V797I Neutral Neutral O15303 E781K Disease Disease O60481 K405E Disease Neutral O60481 T323M Disease Neutral O60481 H286R Disease Disease O60481 C253S Disease Disease O60481 W255G Disease Disease P01185 G93W Disease Disease P01185 C105Y Disease Disease P01185 Y21H Disease Disease P01185 P82L Neutral Neutral P01185 C59Y Disease Disease P01185 G45R Disease Disease P01185 G54R Disease Disease P01185 C52R Disease Disease P01185 V67A Disease Neutral P01185 A19T Disease Disease P01185 C92S Disease Disease P01185 L81P Disease Disease P01185 C116G Disease Disease P01185 G88S Disease Disease P01185 C116R Disease Disease P01185 P55L Disease Disease P01185 S87F Disease Disease P01185 S17F Disease Disease P01185 G54V Disease Disease P01185 G88R Disease Disease P01185 G96V Disease Disease P01185 G96C Disease Disease P01185 G96D Disease Disease P01185 C92Y Disease Disease P01185 G48V Disease Neutral P01185 C59R Disease Disease P01185 P26L Disease Disease P01185 R97P Disease Disease P01185 C104F Disease Disease P01185 C98S Disease Disease P01185 A99P Disease Disease P01185 C116W Disease Disease P01185 C58F Disease Disease P01185 C98G Disease Disease P01185 R51C Disease Disease P01185 E78G Disease Disease P01185 C104G Disease Disease P01185 A19V Disease Disease P01185 C105R Disease Disease P01185 R97C Disease Disease P01185 G119V Neutral Neutral O00445 R111Q Neutral Neutral P06132 G25E Disease Disease P06132 E218K Disease Disease P06132 P235S Disease Disease P06132 S219F Disease Disease P06132 M324T Disease Neutral P06132 L216Q Disease Disease P06132 R193P Disease Disease P06132 V134Q Disease Disease P06132 G318R Disease Neutral P06132 I260T Disease Neutral P06132 A80S Disease Disease P06132 L161Q Disease Disease P06132 R142Q Disease Disease P06132 R332H Disease Disease P06132 G156D Disease Disease P06132 P62L Disease Disease P06132 R144P Disease Disease P06132 L195F Disease Disease P06132 I334T Disease Disease P06132 N304K Disease Disease P06132 G303S Disease Disease P06132 L253Q Disease Disease P06132 F229L Disease Disease P06132 F46L Disease Disease P06132 E167K Disease Disease P06132 G281E Disease Disease P06132 A80G Disease Disease P06132 R292G Disease Disease P06132 M165R Disease Disease P06132 G281V Disease Disease P06132 H220P Disease Disease P06132 L282R Disease Disease P06132 F232L Disease Disease P06132 Y311C Disease Disease Q6ZU64 M66L Neutral Neutral Q9Y242 P241L Neutral Neutral Q9Y242 M211V Neutral Neutral Q99828 S44T Neutral Neutral Q8N9H6 L39P Neutral Disease Q8N3G9 E407V Neutral Neutral O75324 G88S Neutral Neutral O75324 V17I Neutral Neutral Q6P9F7 Q419K Neutral Neutral P06307 R95W Neutral Disease P06307 G32E Neutral Neutral Q9UK85 E214K Neutral Neutral Q9UK85 A29T Neutral Neutral Q9UK85 M109R Neutral Neutral Q70JA7 D764G Neutral Disease Q70JA7 G615E Neutral Neutral Q8TD55 P290S Neutral Neutral Q12794 E268K Disease Disease Q2M3T9 A346S Neutral Neutral O43820 H113Y Neutral Neutral Q12891 A18S Neutral Neutral Q6ZSG2 A147V Neutral Neutral P55268 N1380K Disease Neutral P55268 E987K Neutral Neutral P55268 R246W Disease Disease A4D0S4 N866S Neutral Neutral A4D0S4 M44T Neutral Neutral A4D0S4 T1350N Neutral Neutral P55268 R246Q Disease Disease A4D0S4 H1510Y Neutral Neutral A4D0S4 H234Y Neutral Disease P07942 R1022Q Neutral Disease A4D0S4 R1612S Neutral Neutral P07942 G860S Neutral Disease P55268 C321R Disease Disease P07942 V670A Neutral Disease A4D0S4 V591F Neutral Neutral P55268 L1393F Disease Neutral Q8N4A0 V506I Neutral Neutral Q10471 V554M Neutral Neutral Q8N4A0 I270T Neutral Neutral Q7Z6W7 E41A Neutral Neutral Q9HB75 Q331R Neutral Neutral Q07444 R135S Neutral Disease Q07444 P19R Neutral Neutral P26717 S102F Neutral Disease P26717 S2N Neutral Neutral P51959 N178H Neutral Neutral P51959 F179L Neutral Neutral Q00059 S12T Neutral Neutral P48730 T44A Disease Neutral Q9P2G9 P520R Neutral Neutral Q7Z4S6 M356T Disease Neutral Q7Z4S6 M947T Disease Neutral Q7Z4S6 R954W Disease Disease Q7Z4S6 M947R Disease Neutral Q7Z4S6 R954Q Disease Neutral Q7Z4S6 M947V Disease Neutral Q7Z4S6 I1010T Disease Neutral Q9NP87 E107D Neutral Neutral Q9NP87 L484F Neutral Neutral Q9NP87 V246F Neutral Disease Q9NP87 G220A Neutral Disease O60678 S470C Neutral Disease O60678 N508S Neutral Disease O60678 L440V Neutral Neutral Q8NEE8 A872S Neutral Neutral Q8NEE8 M405T Neutral Neutral Q8NEE8 E588G Neutral Neutral Q96D53 T318M Neutral Disease Q96D53 T462M Neutral Neutral Q96D53 R78C Neutral Disease Q96D53 H174R Neutral Neutral Q96D53 T352R Neutral Neutral Q96PB1 R386S Neutral Disease P31785 C182R Disease Disease P31785 C115R Disease Disease P31785 L172P Disease Disease P31785 S241I Disease Disease P31785 G114D Disease Disease P31785 H123P Disease Neutral P31785 C231Y Disease Disease P31785 C115F Disease Disease P31785 G232R Disease Neutral P31785 E68G Disease Neutral P31785 Y89C Disease Disease P31785 L162H Disease Neutral P31785 N84K Disease Disease P31785 Y105C Disease Disease P31785 R226H Disease Neutral P31785 R222C Disease Neutral P31785 L293Q Disease Neutral P31785 Y125N Disease Neutral P31785 L183S Disease Disease P31785 Q144P Disease Neutral P31785 L172Q Disease Disease P31785 C62G Disease Disease P31785 D39N Disease Disease P31785 R285Q Disease Disease P31785 I153N Disease Disease P31785 F227C Disease Neutral P31785 L230P Disease Disease P31785 R226C Disease Neutral P31785 R224W Disease Disease P31785 M270R Disease Neutral P31785 W240C Disease Disease P31785 A156V Disease Neutral P31785 E109K Neutral Neutral P31785 E68K Disease Neutral P28715 V590I Neutral Neutral P28715 E399K Neutral Neutral P28715 D1104H Neutral Neutral P28715 R1080Q Neutral Neutral P28715 A792V Disease Disease P28715 C529S Neutral Neutral P28715 Q256R Neutral Neutral P28715 L858P Disease Disease P28715 Q680R Neutral Neutral P28715 V145I Neutral Neutral P28715 P72H Disease Disease P28715 S311C Neutral Neutral P28715 H181R Neutral Neutral P28715 R1009H Neutral Neutral P28715 N879S Neutral Neutral P28715 V597L Neutral Neutral P28715 M254V Neutral Disease P28715 A1119V Neutral Neutral P28715 A874T Disease Disease Q9Y5Y6 M285I Neutral Neutral Q9Y5Y6 R381S Neutral Neutral Q9Y5Y6 G827R Disease Disease Q96CW6 D45G Neutral Neutral Q96CW6 V24M Neutral Neutral Q96CW6 S116A Neutral Neutral Q96CW6 Y220C Neutral Disease P54108 S106P Neutral Disease P54108 A134S Neutral Neutral Q8NA82 G241E Neutral Neutral Q8NA82 S319F Neutral Neutral Q8NA82 E742K Neutral Disease Q96CM3 E155D Neutral Neutral Q96CM3 Q44R Neutral Neutral Q96CM3 A209V Neutral Neutral Q96CM3 D58G Neutral Neutral Q8N402 P97L Neutral Neutral Q8N402 T131P Neutral Neutral Q8N402 T114S Neutral Neutral Q17RC7 R77W Neutral Neutral Q17RC7 D93E Neutral Neutral Q17RC7 R675Q Neutral Neutral Q17RC7 L185H Neutral Neutral O75841 R113Q Neutral Neutral O00322 M257T Neutral Neutral Q8N878 R274C Neutral Neutral Q8N878 Q456E Neutral Neutral Q01344 I129V Neutral Neutral Q01344 V262A Neutral Neutral Q9HBH9 D73N Neutral Disease P41225 A43T Neutral Neutral Q76N32 G74S Neutral Neutral Q96BW9 N116S Neutral Neutral P16435 Y575C Disease Disease P16435 V489E Disease Disease P16435 Y178D Disease Disease P16435 R454H Disease Disease P16435 C566Y Disease Disease P16435 V605F Disease Disease P16435 A500V Neutral Neutral P16435 R551Q Neutral Neutral P16435 A284P Disease Disease Q7Z5Y7 S171T Neutral Neutral P01019 M268I Neutral Neutral P01019 R375Q Disease Disease P01019 L392M Neutral Neutral P01019 E98K Neutral Neutral P01019 T207M Neutral Neutral P01019 T137M Neutral Neutral P01019 L43F Neutral Neutral P01019 P335S Neutral Neutral P01019 M268T Neutral Neutral P01019 L244R Neutral Disease Q14032 M76V Disease Disease P29475 N725D Neutral Neutral P29475 G864D Neutral Neutral P29475 Q1064R Neutral Neutral P29475 P228S Neutral Neutral P29475 D394A Neutral Neutral Q9Y615 R45C Neutral Neutral Q9Y615 V340M Neutral Neutral Q9Y615 A161P Neutral Disease P01229 M15I Neutral Neutral P01229 G122S Neutral Neutral P01229 A18T Neutral Neutral P01229 W28R Neutral Neutral P01229 I35T Neutral Neutral P01229 Q74R Disease Disease O15409 R553H Disease Disease Q9BXW7 R369S Neutral Neutral Q02447 T164A Neutral Neutral P08047 T737A Neutral Neutral Q8IYK2 D434E Neutral Neutral Q8IYK2 T444S Neutral Neutral Q8IYK2 P499T Neutral Neutral P24666 Q106R Neutral Neutral Q4G0S4 T359M Neutral Neutral Q9UND3 R93C Neutral Neutral P13804 V157G Disease Disease P13804 T266M Disease Disease P13804 T171I Neutral Disease P13804 G116R Disease Disease P24001 D152N Neutral Neutral Q969H0 T144R Neutral Neutral Q969H0 R133G Neutral Neutral Q969H0 E115K Neutral Neutral Q969H0 R465C Disease Neutral Q969H0 S668G Neutral Disease Q969H0 R505L Disease Neutral Q9UKY0 T26P Neutral Neutral Q9UKY0 L149S Neutral Neutral Q9UKY0 T174M Neutral Neutral Q9UKY0 F70L Neutral Neutral Q9UKY0 H31R Neutral Neutral Q9UKY0 S6I Neutral Neutral Q9UKY0 S22P Neutral Neutral Q9UKY0 P56L Neutral Neutral Q86X67 G81D Neutral Neutral O14773 G389E Disease Disease O14773 S62L Neutral Neutral O14773 G473R Disease Disease O14773 R447H Disease Disease O14773 V277M Disease Neutral O14773 I287N Disease Disease O14773 R175H Neutral Neutral O14773 Q278P Disease Disease O14773 S475L Disease Disease O14773 C365R Disease Disease O14773 G284V Disease Disease O14773 R127Q Disease Neutral O14773 F481C Disease Disease O14773 T353P Disease Disease O14773 S153P Disease Disease O14773 R206C Disease Disease O14773 R185C Neutral Disease O14773 E343K Disease Neutral O14773 G77R Disease Disease O14773 N286S Disease Disease O14773 C365Y Disease Disease O14773 Q422H Disease Disease O14773 R206H Disease Disease O14773 A454E Disease Disease O14773 Q100R Neutral Neutral O14773 K428N Disease Neutral O14773 V385D Disease Disease Q75LS8 V125G Neutral Disease P31146 R415K Neutral Neutral P31146 T443P Neutral Neutral Q96EY7 A2V Neutral Neutral Q96EY7 S681G Neutral Neutral Q96EY1 Y75N Neutral Disease Q14258 V89G Neutral Neutral Q14258 L358P Neutral Disease Q9NUQ9 N169K Neutral Neutral Q5VX65 M219V Neutral Neutral Q5VX65 V301M Neutral Disease P31513 R492W Disease Disease Q01740 H97Q Neutral Disease P31513 V257M Neutral Disease P31513 M434I Disease Disease P31513 M66I Disease Neutral Q99518 R238Q Neutral Disease Q99518 E314G Neutral Disease Q01740 K373R Neutral Neutral Q01740 F327L Neutral Neutral P31513 D198E Neutral Disease P31513 L360P Neutral Disease Q01740 S227T Neutral Neutral P31513 R205C Neutral Disease P31512 E339Q Neutral Neutral Q99518 F81S Neutral Disease P31513 P153L Disease Disease P31512 G372S Neutral Neutral P31513 V277A Neutral Neutral P31513 G503R Neutral Neutral Q99518 F69Y Neutral Neutral P31512 F536L Neutral Neutral Q01740 R223Q Neutral Disease Q99518 N413K Neutral Neutral P31512 V323A Neutral Neutral Q01740 I322V Neutral Neutral P31513 D132H Neutral Neutral O60774 V257I Neutral Neutral Q01740 R474H Neutral Disease P31513 E158K Neutral Disease Q01740 I303V Neutral Neutral P31513 E362Q Neutral Neutral Q99518 R391T Neutral Disease Q99518 F182S Neutral Disease P31512 I37T Neutral Neutral P31513 A52T Disease Neutral P31513 R387L Disease Disease P31513 E308G Neutral Disease Q99518 S195L Neutral Disease P49326 P457L Neutral Disease Q99518 D36G Neutral Disease Q99518 V59I Neutral Neutral P31512 L544R Neutral Disease P49326 R506S Neutral Neutral O60774 V127I Neutral Neutral P49326 P400A Neutral Disease P31513 E32K Disease Disease Q01740 I303T Neutral Disease P31513 N61S Disease Disease P35611 Y270N Neutral Disease P35611 S586C Neutral Neutral P35611 E376D Neutral Disease P35611 G460W Neutral Neutral P35612 T439A Neutral Disease P35612 S663R Neutral Neutral P35612 D28N Neutral Neutral P35611 R6C Neutral Neutral P35612 E335D Neutral Neutral P35611 N510I Neutral Disease P06703 H27R Neutral Neutral P33763 D54G Neutral Neutral P06703 N69S Neutral Neutral P06703 G90D Neutral Disease P06703 I83T Neutral Neutral Q9Y467 S122P Neutral Neutral Q9Y467 S75C Neutral Neutral Q9Y467 R746G Neutral Neutral Q6PCE3 I531V Neutral Neutral Q6PCE3 L14P Neutral Neutral Q96G03 G10D Neutral Neutral Q96G03 E488D Neutral Neutral Q8N7S2 V4G Neutral Neutral Q8N7S2 H51R Neutral Neutral P51795 S244L Disease Disease P51795 S520P Disease Disease P51795 R280P Disease Disease P51795 G57V Disease Disease P51795 L200R Disease Disease P51795 G512R Disease Disease P51795 E527D Disease Disease P51795 G506E Disease Disease P07098 T161A Neutral Disease P38571 H129R Disease Disease P38571 G23R Neutral Neutral P38571 L200P Disease Disease Q5VYY2 R418W Neutral Neutral P07098 F224I Neutral Neutral Q5W064 V210I Neutral Neutral Q5VXJ0 M331I Neutral Neutral P07098 P348T Neutral Disease Q5VXJ0 I391T Neutral Neutral Q5VXI9 T244N Neutral Neutral P38571 T16P Neutral Neutral P38571 H129P Disease Disease P38571 V29L Neutral Neutral Q8WZ42 S4465N Disease Neutral Q8WZ42 A743V Disease Neutral Q8WZ42 R740L Disease Disease Q8WZ42 R279W Disease Neutral Q8WZ42 V54M Disease Disease Q8WZ42 S3799Y Disease Neutral Q8WZ42 W976R Disease Disease Q9Y3V2 A47V Neutral Neutral Q9Y3V2 K86N Neutral Neutral P21728 S199A Neutral Neutral P21728 T37P Neutral Disease P21918 A286V Neutral Neutral P21918 V238I Neutral Neutral P21918 C62S Neutral Neutral P21918 S233N Neutral Disease P21918 G110E Neutral Disease P21918 P330Q Neutral Neutral P21918 A269V Neutral Neutral P21918 N351D Neutral Disease P21728 T37R Neutral Disease P21918 L88R Neutral Disease P21918 R247H Neutral Neutral P21728 R50S Neutral Neutral P21918 F207V Neutral Neutral P21918 S453C Neutral Neutral A1A4S6 M684V Neutral Neutral Q69YH5 I718V Neutral Neutral Q69YH5 R885S Neutral Neutral Q9UGJ0 R531G Disease Disease Q9UGJ0 R302Q Disease Disease Q9UGJ0 H383R Disease Neutral Q9UGJ0 R531Q Disease Disease Q9UGJ0 N488I Disease Disease Q9UGJ0 T400N Disease Disease Q5TB80 C266S Neutral Neutral Q5TB80 E272Q Neutral Neutral Q13530 T437A Neutral Neutral Q12918 I168T Neutral Disease Q71F56 R1872H Disease Neutral Q71F56 E251G Disease Neutral Q71F56 D2023G Disease Disease Q5M9N0 I297V Neutral Neutral Q5M9N0 E232D Neutral Neutral P04921 K124E Neutral Neutral P11182 I98M Disease Disease P11182 G384S Disease Disease P11182 F276C Disease Neutral Q9BRD0 P148L Neutral Neutral Q9BRD0 R120C Neutral Neutral Q9BRD0 R242I Neutral Neutral Q03135 P132L Disease Disease Q06323 S55N Neutral Neutral Q06323 T244K Neutral Neutral Q9BUB5 L158V Neutral Neutral Q9BUB5 R446Q Neutral Neutral Q9BUB5 D308N Neutral Disease Q9BUB5 K49Q Neutral Neutral Q6DN12 A877T Neutral Neutral Q8TC99 S36P Neutral Neutral Q8NAT2 K358E Neutral Neutral Q8NAT2 M104T Neutral Neutral Q8NAT2 E722K Neutral Neutral P13224 Y113C Disease Neutral P13224 A133P Disease Neutral Q9NQW8 T298P Neutral Disease Q9NQW8 W234C Neutral Disease Q9NQW8 P750S Neutral Neutral Q9NQW8 E755G Neutral Neutral Q9NQW8 S435F Disease Disease Q9NQW8 I307V Neutral Neutral Q9NQW8 R203Q Neutral Neutral Q9NQW6 R185K Neutral Neutral Q9NQW6 S65W Neutral Disease Q8IZ40 T514A Neutral Neutral Q8NFZ8 T225A Neutral Disease Q5T9L3 V465I Neutral Neutral P01286 L75F Neutral Neutral Q13285 R255L Disease Neutral Q13285 G146A Neutral Neutral Q14390 E70G Neutral Neutral Q6ZR62 L27P Neutral Neutral Q6P3S6 P471A Neutral Neutral Q00796 L239Q Neutral Neutral Q96FN9 R6W Neutral Neutral Q96LM9 K141E Neutral Neutral P82094 D798H Neutral Neutral P10809 V98I Disease Disease Q13495 P286S Neutral Neutral Q13495 N589S Neutral Neutral Q13495 Q507R Neutral Neutral Q7Z412 L153V Neutral Neutral Q7Z412 G89R Disease Disease Q7Z412 R98W Disease Neutral Q7Z412 L45P Disease Disease P42336 Q546P Disease Disease P42336 G106V Disease Disease P42336 I391M Neutral Disease P42336 Q546K Disease Neutral P42336 H1047Y Disease Neutral P42336 E542Q Disease Neutral P42336 H1047R Disease Neutral P42336 E453Q Disease Disease P42336 G1050D Disease Disease P42336 E545A Disease Neutral P42336 Q546R Disease Neutral P42336 E542K Disease Neutral P42336 Y1021H Disease Neutral P42336 E545K Disease Neutral P42336 E542V Disease Neutral P42336 H1065L Disease Neutral P42336 T1052K Disease Disease P42336 E545G Disease Disease P42336 R38H Disease Disease P42336 R88Q Disease Neutral P42336 Y1021C Disease Disease P42336 M1043I Disease Neutral P42336 Q546E Disease Neutral P42336 G1007R Disease Disease P42336 Y343C Disease Neutral P42336 A1035V Disease Disease P42336 H1065Y Disease Neutral P42336 T1025N Disease Neutral P42336 C420R Disease Disease P42336 R1023Q Disease Neutral P42336 Y1021N Disease Disease P42336 H1047L Disease Neutral Q7Z5H4 R350C Neutral Neutral Q6MZZ7 I596T Neutral Neutral O14815 D164N Neutral Neutral P07384 T103A Neutral Neutral P17655 K677Q Neutral Neutral Q9UMQ6 S507R Neutral Disease Q9UMQ6 V404A Neutral Neutral O14815 H327Q Neutral Neutral O14815 M611I Neutral Neutral P17655 K476R Neutral Neutral P17655 K568Q Neutral Neutral Q6MZZ7 A280T Neutral Neutral O14815 S122R Neutral Disease O14815 I234T Neutral Disease P17655 E521Q Neutral Neutral Q9UMQ6 I484V Neutral Neutral P07384 V676I Neutral Neutral P17655 E22D Neutral Neutral O14815 A102V Neutral Disease Q6MZZ7 H249Y Neutral Disease O14815 R458W Neutral Disease O14815 A239T Neutral Neutral O14815 K322Q Neutral Neutral P07384 R433P Neutral Disease P17655 S68G Neutral Neutral Q9UMQ6 V229M Neutral Neutral P07384 G492R Neutral Disease O14815 R522W Neutral Neutral Q9UMQ6 S691N Neutral Neutral O14815 E342K Neutral Neutral O14815 R277W Neutral Disease Q8TDF6 Q120L Neutral Neutral Q8TDF6 R261C Neutral Disease Q8TDF6 T18I Neutral Neutral Q8TDF6 R335G Neutral Disease Q8TDF6 V145A Neutral Neutral Q5T2Q4 R176Q Neutral Neutral Q5T2Q4 I288V Neutral Neutral Q5T2Q4 V57E Neutral Neutral P17844 S480A Neutral Neutral P05177 R281W Neutral Disease P10635 G42R Neutral Disease P04798 R477W Neutral Disease P08686 P105L Disease Neutral P11712 I359T Neutral Neutral P11509 I471T Neutral Neutral P08686 S301Y Disease Neutral P11509 V365M Neutral Disease P33261 R433W Neutral Disease P08686 G291S Disease Disease P51589 R158C Neutral Disease P11509 S29N Neutral Neutral P11509 E419D Neutral Neutral P04798 M331I Neutral Neutral P33261 S51G Neutral Neutral Q16678 D449E Neutral Neutral P04798 V482M Neutral Neutral P10635 P469A Neutral Disease P08686 M283L Disease Disease P10635 H94R Neutral Neutral P10635 E418K Neutral Disease P20813 R487C Neutral Neutral Q16678 Q68R Neutral Disease P10635 R343G Neutral Disease P05093 Y64S Disease Neutral Q16678 A119S Neutral Neutral P04798 I448N Neutral Disease P10635 L91M Neutral Disease P05093 R496C Disease Disease P33261 E92D Neutral Neutral P11509 R485L Neutral Disease P10635 I297L Neutral Neutral P05177 S18C Neutral Disease P08686 G178A Disease Disease P10635 S486T Neutral Neutral Q16678 N453S Neutral Neutral P33261 R329H Neutral Neutral Q16696 R101Q Neutral Disease P08686 K98R Neutral Neutral P05093 F93C Disease Disease Q16696 R494C Neutral Disease P05177 T438I Neutral Neutral P08686 G90V Disease Disease P20813 T26S Neutral Neutral P33261 P227L Neutral Disease P10635 G212E Neutral Disease P10635 T107I Neutral Neutral P08686 S268T Neutral Neutral P08686 R356W Disease Neutral P08686 R341W Disease Neutral P08686 R479L Disease Neutral P05177 D104N Neutral Neutral P05181 V179I Neutral Neutral P08686 I236N Disease Neutral P33261 R442C Neutral Disease P11712 G417D Neutral Disease P20813 R29S Neutral Neutral P11509 G5R Neutral Disease P05181 V389I Neutral Neutral P20813 T306S Neutral Disease P08686 R435C Disease Neutral P10635 R296C Neutral Neutral P10632 L390S Neutral Neutral P05093 P35L Disease Disease Q16678 L432V Neutral Neutral P04798 I462V Neutral Neutral Q16678 A443G Neutral Neutral P11509 K476R Neutral Neutral P51589 D342N Neutral Disease Q16696 R25Q Neutral Disease P05093 D116V Disease Neutral P08686 C169Y Disease Neutral P05093 F114V Disease Disease P04798 R464S Neutral Disease P11509 L160H Neutral Disease Q16678 R469W Disease Disease Q16678 P379L Neutral Disease P20813 G99E Neutral Disease P11712 R144C Neutral Disease P08686 R483Q Disease Disease P08686 D183E Neutral Neutral P11509 R203S Neutral Neutral P05093 S106P Disease Disease P11509 S224P Neutral Neutral P04798 F470V Neutral Disease P11509 K194E Neutral Neutral P20813 S259R Neutral Disease P05177 I386F Neutral Neutral P10635 I369T Neutral Neutral P33261 A161P Neutral Disease P20813 K139E Neutral Disease Q16678 R390H Neutral Neutral P05177 G73R Neutral Disease P08686 P30L Disease Disease P05093 R440H Disease Disease P51589 I192N Neutral Disease P10632 K399R Neutral Neutral P05093 P428L Disease Disease P05093 P342T Disease Neutral P05177 S298R Neutral Disease P05177 P42R Neutral Disease P11712 L19I Neutral Neutral P05177 L111F Neutral Neutral P11712 I359L Neutral Neutral Q16678 D441H Neutral Neutral P10632 R139K Neutral Disease P33261 E122A Neutral Neutral P20813 N289K Neutral Neutral P10635 P34S Neutral Disease P11712 Y358C Neutral Neutral P20813 Q172H Neutral Neutral P10635 H324P Neutral Disease P08686 R356P Disease Disease P11712 H251R Neutral Disease P20813 I391N Neutral Neutral P05093 R347H Disease Disease P11509 G479V Neutral Disease P08686 L363W Disease Neutral P10635 R26H Neutral Disease P08686 V281G Disease Disease P08686 R408C Disease Disease P08686 G424S Disease Disease P10635 G169R Neutral Disease Q16678 R48G Neutral Disease P10635 E155K Neutral Disease Q16696 D158E Neutral Neutral P05093 R96W Disease Disease P05181 R76H Neutral Disease P04798 I78T Neutral Neutral Q16678 D374N Disease Disease P33261 R144H Neutral Disease Q16678 G365W Disease Disease P05177 R431W Neutral Disease P10635 V11M Neutral Neutral P33261 M74T Neutral Neutral P04798 G45D Neutral Disease P33261 I19L Neutral Neutral P11509 F118L Neutral Disease P08686 P30Q Disease Disease P05093 N177D Disease Neutral P33261 R150H Neutral Neutral P05177 D348N Neutral Disease P33261 R410C Neutral Neutral P05093 C22W Neutral Disease P20813 I328T Neutral Disease Q16678 G61E Disease Disease P08686 R483W Disease Disease Q8TAV3 A181T Neutral Neutral Q16678 P437L Neutral Disease P51589 N404Y Neutral Disease P05177 E168Q Neutral Disease P08686 R339H Disease Disease P11509 R128Q Neutral Disease P33260 T385M Neutral Disease P05181 H457L Neutral Neutral P51589 R49S Neutral Neutral Q16678 Y81N Neutral Disease P10635 F120I Neutral Neutral Q16678 S206N Neutral Neutral P04798 R93W Neutral Disease P51589 T143A Neutral Neutral Q16678 R266L Neutral Disease P20813 R140Q Neutral Disease P08686 R341P Disease Disease Q16696 V323L Neutral Disease P08686 R124H Disease Neutral P08686 P453S Disease Disease P11509 N418D Neutral Neutral P05177 I314V Neutral Neutral P08686 N493S Disease Neutral P33261 V331I Neutral Neutral P08686 A362V Disease Neutral Q16678 E387K Neutral Disease P05177 R456H Neutral Disease P05093 R496H Disease Disease P05093 R358Q Disease Neutral P05177 T83M Neutral Disease P05093 H373L Disease Disease P33261 R132Q Neutral Disease P05177 S212C Neutral Neutral P04798 I286T Neutral Disease P33261 L17P Neutral Disease P05177 F21L Neutral Disease P33261 F168L Neutral Neutral P08686 G64E Disease Disease P11712 R150H Neutral Neutral P04798 T173R Neutral Disease P10635 A237S Neutral Neutral P11712 E272G Neutral Neutral P04798 P492R Neutral Disease P08686 H365Y Disease Disease P04798 T461N Neutral Disease P11712 P489S Neutral Disease P05177 C406Y Neutral Disease P08686 L300F Disease Disease P05177 F205V Neutral Disease P10635 S311L Neutral Disease P51589 N124S Neutral Neutral P20813 Q21L Neutral Neutral P05177 G299S Neutral Neutral P10635 A85V Neutral Disease P08686 G291C Disease Disease P10632 I269F Neutral Neutral P11712 R335W Neutral Disease P04798 R279W Neutral Disease P08686 R354H Disease Disease P05177 R377Q Neutral Neutral P08686 R483P Disease Disease P08686 P482S Disease Disease P10635 H478Y Neutral Neutral P08686 R356Q Disease Neutral P08686 H62L Disease Neutral P20813 M46V Neutral Neutral Q16696 R257C Neutral Neutral P05093 Y329D Disease Disease P08686 I172N Disease Disease P08686 M239K Disease Neutral P05177 F186L Neutral Neutral P10632 I264M Neutral Disease Q16696 F453Y Neutral Disease Q96SQ9 P466L Neutral Disease P08686 A15T Disease Neutral P08686 K102R Neutral Neutral P20813 R22C Neutral Disease P33261 W120R Neutral Disease P08686 R354C Disease Disease P08686 V281L Disease Neutral P04798 M66V Neutral Neutral P08686 V237E Disease Neutral P04798 R464C Neutral Disease P20813 K262R Neutral Neutral P08686 L261P Disease Disease P51589 V113M Neutral Neutral P08686 V211L Disease Neutral P08686 E380D Disease Neutral P05093 R362C Disease Disease P08686 L317M Disease Neutral P20813 D28G Neutral Neutral P11712 L413P Neutral Disease P08686 R426H Disease Disease Q16678 R368H Disease Disease P11712 D360E Neutral Neutral P05093 F417C Disease Disease P05093 R347C Disease Neutral P08686 G291R Disease Disease P10632 I244V Neutral Neutral Q16678 W57C Neutral Disease P05093 W406R Disease Disease P20813 R29P Neutral Disease P10635 E410K Neutral Neutral P20813 P167A Neutral Neutral P10635 R28C Neutral Disease Q9UBZ4 R141C Neutral Disease P51608 P302R Disease Neutral P51608 T158M Disease Neutral P51608 E394K Neutral Neutral P51608 P302L Disease Neutral P51608 D97E Disease Neutral P51608 P101R Disease Neutral P51608 P302A Disease Neutral P51608 G232A Neutral Neutral P51608 P225R Disease Neutral P51608 R133H Disease Disease P51608 Y120D Disease Disease P51608 R344W Disease Neutral P51608 S291A Neutral Neutral P51608 P402L Neutral Neutral P51608 D97Y Disease Neutral P51608 V412I Neutral Neutral P51608 A439T Neutral Neutral P51608 P225L Disease Neutral P51608 E397K Neutral Neutral P51608 A140V Disease Neutral P51608 S359P Neutral Neutral P51608 L100V Disease Neutral P51608 R306C Disease Disease P51608 P480S Neutral Neutral P51608 P388L Neutral Neutral P51608 P251L Neutral Neutral P51608 A201V Neutral Neutral P51608 P152R Disease Neutral P51608 R111G Disease Neutral P51608 R167W Disease Neutral P51608 P302H Disease Neutral P51608 L100R Disease Disease P51608 D156G Disease Neutral P51608 P322A Disease Neutral P51608 P101T Disease Neutral P51608 T197M Neutral Neutral P51608 G428S Disease Neutral P51608 E137G Disease Neutral P51608 A181V Neutral Neutral P51608 P376S Neutral Neutral P51608 F155S Disease Disease P51608 P322L Disease Neutral P51608 R133C Disease Disease P51608 R306H Disease Disease P51608 G161V Disease Neutral P51608 T203M Neutral Neutral P51608 A444T Neutral Neutral P51608 R106Q Disease Neutral P51608 R453Q Disease Neutral P51608 L124F Disease Neutral P51608 P101S Disease Neutral P51608 Q128P Disease Disease P51608 K210I Disease Neutral P51608 A287P Neutral Neutral P51608 S134C Disease Neutral P51608 S86C Neutral Neutral P51608 R106W Disease Neutral P51608 T228S Neutral Neutral P51608 P101L Disease Neutral P51608 P101H Disease Neutral P51608 P399L Disease Neutral P51608 S229L Neutral Neutral P51608 F155I Disease Disease P51608 P322S Disease Neutral P51608 E10Q Disease Neutral P51608 K305R Disease Neutral P51608 K135E Disease Disease P51608 T196S Neutral Neutral P51608 K284E Disease Neutral P51608 T158A Disease Neutral Q08378 K1185R Neutral Neutral Q08378 P264L Neutral Neutral Q08378 G70E Neutral Neutral P53609 I103V Neutral Neutral Q7Z6Z6 T200I Neutral Neutral Q7Z6Z6 L140F Neutral Neutral Q7Z6Z6 W286R Neutral Neutral Q9Y5P8 D163E Neutral Neutral Q9ULI1 L569M Neutral Neutral Q5T2S8 N935K Neutral Neutral Q8IVW4 M394T Neutral Neutral Q5HYA8 Y513C Disease Neutral Q5HYA8 V604I Neutral Neutral Q5HYA8 G545E Disease Neutral Q5HYA8 Q376P Disease Disease Q9H4B4 S618P Neutral Disease Q9H4B4 S498L Neutral Neutral Q9H4B4 L283F Neutral Neutral Q9H4B4 R483C Neutral Neutral Q9H4B4 L68F Neutral Disease Q9H4B4 T61S Neutral Neutral Q12767 I1040T Neutral Neutral O75355 A496V Neutral Neutral O75355 E440D Neutral Neutral O75355 L505F Neutral Neutral Q8IXT1 D757N Neutral Neutral Q8IXT1 R460S Neutral Neutral Q8IXT1 I217T Neutral Neutral Q8IXT1 V842I Neutral Neutral Q8IXT1 P795R Neutral Neutral Q8N7B1 V20L Neutral Neutral Q8N7B1 A2T Neutral Neutral P13866 D28G Disease Disease P13866 N51S Neutral Neutral P31639 N654S Disease Disease P13866 R135W Disease Disease P13866 D28N Disease Disease P13866 G318R Disease Disease P13866 A468V Disease Disease Q9NY91 A46T Neutral Disease P13866 A411T Neutral Neutral Q08493 R344Q Neutral Disease Q92982 D110A Neutral Neutral O14582 D47Y Disease Disease O14582 F83S Disease Disease O14582 V130D Disease Disease O14582 S73L Disease Disease Q9H9L4 T445P Neutral Neutral Q9H9L4 N313S Neutral Neutral P15144 A311V Neutral Disease Q9NZ08 R127P Neutral Neutral P15144 L243P Neutral Disease Q9NZ08 D575N Neutral Neutral Q9NZ08 Q730E Neutral Neutral P15144 I603M Neutral Neutral Q6P179 L669Q Neutral Disease P15144 I603K Neutral Disease P15144 D242Y Neutral Disease Q9NZ08 G346D Neutral Disease P15144 V20M Neutral Neutral Q9NZ08 R725Q Neutral Neutral P15144 T321M Neutral Disease Q9NZ08 K528R Neutral Disease Q6Q4G3 V640F Neutral Neutral Q6P179 K392N Neutral Neutral P15144 S752N Neutral Neutral Q6P179 P214L Neutral Disease Q9NZ08 I276M Neutral Neutral Q6Q4G3 F689L Neutral Neutral Q6Q4G3 V936I Neutral Neutral P15144 R86Q Neutral Neutral Q9NZ08 M349V Neutral Neutral A2A3L6 P532A Neutral Neutral A2A3L6 E231G Neutral Disease A2A3L6 N550S Neutral Neutral Q5T6F2 N606S Neutral Neutral Q5T6F2 A756V Neutral Neutral Q14157 Q482H Neutral Neutral Q9Y3I0 L343F Neutral Neutral Q8N961 T732A Neutral Neutral Q8N961 H64Q Neutral Neutral Q5VZ46 H214Y Neutral Neutral Q5VZ46 R740W Neutral Neutral Q5VZ46 L801F Neutral Neutral Q5VZ46 D1078N Neutral Neutral Q13315 M1040V Disease Neutral Q13315 W2491R Disease Disease Q13315 N768D Disease Neutral Q13315 D126E Neutral Neutral Q13315 E2139G Disease Neutral Q13315 S333F Neutral Neutral Q13315 N750K Disease Neutral Q13315 N504S Neutral Neutral Q13315 T2438I Neutral Neutral Q13315 L950R Disease Disease Q13315 Y2470D Disease Disease Q13315 I1407T Disease Neutral Q13315 L546V Neutral Neutral Q13315 A3006P Disease Disease Q13315 T2396S Disease Neutral Q13315 L2890V Disease Disease Q13315 I2702R Disease Disease Q13315 E2423G Disease Neutral Q13315 R2719H Neutral Neutral Q13315 A2420P Disease Disease Q13315 R2849P Disease Disease Q13315 L1910H Disease Neutral Q13315 T935A Neutral Neutral Q13315 L1420P Disease Disease Q13315 D2625Q Disease Neutral Q13315 I323V Disease Neutral Q13315 F858L Neutral Neutral Q13315 G2695A Disease Disease Q13315 M1321I Neutral Neutral Q13315 K224E Disease Neutral Q13315 P2829L Disease Disease Q13315 N1650S Neutral Neutral Q13315 D140H Neutral Neutral Q13315 D1682H Disease Disease Q13315 L1001Q Disease Disease Q13315 Y332C Disease Neutral Q13315 P872S Neutral Neutral Q13315 P1054R Neutral Neutral Q13315 V1913G Disease Neutral Q13315 E1091D Disease Neutral Q13315 V410A Neutral Neutral Q13315 D2016G Disease Disease Q13315 G514D Neutral Disease Q13315 G2063E Disease Disease Q13315 K1454N Neutral Neutral Q13315 K3018N Disease Neutral Q13315 A2274T Disease Neutral Q13315 F570S Disease Neutral Q13315 S1983N Neutral Neutral Q13315 F1463S Disease Disease Q13315 S1691R Disease Neutral Q13315 R250Q Neutral Neutral Q13315 R2486G Disease Disease Q13315 I352T Disease Neutral Q13315 Q2442P Disease Disease Q13315 T1953R Disease Disease Q13315 L2332P Neutral Disease Q13315 A350T Disease Disease Q13315 R3008C Disease Disease Q13315 D2725V Disease Disease Q13315 S49C Neutral Neutral Q13315 A2726V Disease Neutral Q13315 E2164K Disease Neutral Q13315 V2079I Neutral Neutral Q13315 P292L Disease Neutral Q13315 P1382S Neutral Neutral Q13315 R2227C Disease Disease Q13315 P1566R Disease Disease Q13315 D2870N Neutral Disease Q13315 V2424G Disease Neutral Q13315 L2492R Neutral Disease Q13315 D3003N Neutral Neutral Q13315 L1465P Disease Disease Q13315 H1380Y Neutral Neutral Q13315 H2554D Disease Disease Q13315 V1570A Neutral Neutral Q13315 R3008H Disease Neutral Q13315 C2464R Neutral Neutral Q13315 D1853V Neutral Disease Q13315 E2904G Disease Disease Q13315 Y1961C Neutral Neutral Q13315 S2218C Disease Neutral Q13315 R924W Neutral Neutral Q13315 D1853N Neutral Neutral Q13315 F582L Neutral Neutral Q13315 L2307F Neutral Neutral Q13315 C2824Y Disease Disease Q13315 D2725G Disease Disease Q13315 E2668G Disease Neutral Q13315 A2067D Disease Disease Q13315 H1082L Disease Disease Q13315 L2722R Disease Disease Q13315 R2832C Disease Disease Q13315 F2827C Disease Disease Q13315 R785C Disease Neutral Q13315 S2855R Disease Disease Q13315 G2287A Neutral Neutral Q13315 F2732L Disease Disease Q13315 V182L Neutral Neutral Q13315 T1743I Disease Neutral Q13315 R2909G Disease Disease Q13315 Y1475C Neutral Neutral Q13315 S707P Neutral Neutral Q13315 G2867R Disease Disease Q13315 L2656P Disease Disease Q13315 L1420F Neutral Neutral Q9H9S5 Y307N Disease Disease Q9H9S5 Y309C Disease Disease Q9H9S5 A114G Disease Neutral Q9H9S5 P316S Disease Neutral Q9H9S5 P462S Disease Disease Q9H9S5 R339H Disease Disease Q9H9S5 P448L Disease Disease Q9H9S5 Y328S Disease Disease Q9H9S5 L276I Disease Neutral Q9H9S5 P315T Disease Neutral Q9H9S5 R54W Disease Disease Q9H9S5 R143S Disease Neutral Q9H9S5 P217T Disease Neutral Q9H9S5 C318Y Disease Disease Q9H9S5 R339L Disease Disease Q9H9S5 S221R Disease Neutral Q9H9S5 R312C Disease Disease Q9H9S5 D401N Disease Neutral Q9H9S5 Y465S Disease Neutral Q9H9S5 V405L Disease Neutral Q9H9S5 A455D Disease Neutral Q9H9S5 P316R Disease Neutral Q9H9S5 D360N Disease Neutral Q8IWD5 R486H Neutral Neutral Q8WXI4 G202D Neutral Neutral Q8WXI4 M212I Neutral Neutral Q8WXI4 P165L Neutral Disease O95999 R64K Disease Neutral O95999 A5S Disease Neutral O95999 R58G Disease Neutral O95999 V16E Disease Disease O95999 C57R Disease Neutral O95999 T168A Disease Neutral O95999 D101E Disease Neutral O95999 V230I Disease Neutral O95999 G213E Disease Neutral O95999 L174S Disease Neutral O95999 K31E Disease Neutral O95999 S134P Disease Neutral O95999 S218F Disease Neutral Q8TDL5 S479T Neutral Neutral Q8TDL5 I84V Neutral Neutral Q8TDL5 S313I Neutral Neutral Q8TDL5 S298P Neutral Neutral Q15465 I354T Disease Neutral Q15465 E188Q Disease Disease Q15465 A110D Disease Disease Q15465 D88V Disease Disease Q15465 V224E Disease Disease Q15465 R6T Disease Neutral Q15465 N115K Disease Disease Q15465 P347Q Disease Disease Q15465 I111N Disease Disease Q15465 A383T Disease Neutral Q15465 S236R Disease Disease Q15465 A373T Disease Disease Q15465 T267I Disease Disease Q15465 L271P Disease Disease Q15465 G27A Disease Disease Q15465 Q100H Disease Neutral Q15465 T150R Disease Disease Q15465 H140P Disease Disease Q15465 C183F Disease Disease Q15465 W117R Disease Disease Q15465 G290D Disease Neutral Q15465 A226T Disease Neutral Q15465 D222N Disease Neutral Q15465 V332A Disease Disease Q15465 R381P Disease Disease Q15465 I111F Disease Disease Q15465 G31R Disease Disease Q15465 S436L Disease Disease Q15465 P424A Disease Neutral Q15465 H140Q Disease Disease Q15465 W117G Disease Disease Q86UW9 G384E Neutral Neutral Q86UW9 A94T Neutral Neutral Q86UW9 T421A Neutral Neutral A6NGG8 P1254L Neutral Neutral A6NGG8 T580M Neutral Neutral A6NGG8 L792V Neutral Neutral A6NGG8 S13C Neutral Neutral A6NGG8 K421R Neutral Neutral Q9Y258 L18R Neutral Disease P46952 V37I Neutral Neutral P46952 T42S Neutral Neutral Q16698 K333N Neutral Neutral Q3MHD2 P77R Neutral Neutral Q9H2W1 A183S Neutral Neutral Q9H2W1 T185S Neutral Neutral P78332 S353F Disease Neutral Q4ZHG4 D1128E Neutral Neutral Q4ZHG4 T386A Neutral Neutral Q4ZHG4 L1209P Neutral Neutral Q4ZHG4 Q951E Neutral Neutral Q4ZHG4 E411Q Neutral Neutral Q4ZHG4 T1446K Neutral Neutral Q4ZHG4 T1516A Neutral Neutral Q4ZHG4 Q1228R Neutral Neutral O60683 H290Q Disease Disease P20248 V163I Neutral Neutral P21359 K1444N Disease Disease P21359 P2221A Disease Neutral P21359 L763P Disease Disease P21359 V2511L Neutral Neutral P21359 L1196R Disease Disease P21359 L1243P Disease Disease P21359 G848E Disease Disease P21359 D2012N Disease Neutral P21359 L1147P Disease Disease P21359 W1952R Disease Disease P21359 L194R Disease Disease P21359 L844R Disease Disease P21359 C324R Disease Disease P21359 R765H Neutral Neutral P21359 W784C Disease Disease P21359 T780K Disease Neutral P21359 L898P Disease Disease P21359 R1412S Disease Disease P21359 K1444R Disease Disease P21359 R873C Disease Neutral P21359 D338G Disease Neutral P21359 M1073V Disease Neutral P21359 E337V Disease Disease P21359 Y491C Disease Neutral P21359 G2001R Disease Disease P21359 L549P Disease Disease P21359 V1453L Disease Disease P21359 R1276P Disease Disease P21359 L145P Disease Disease P21359 G629R Disease Neutral P21359 F1193C Disease Disease P21359 L532P Disease Disease P21359 S665F Disease Neutral P21359 L844F Disease Neutral P21359 N1451T Disease Disease P21359 L2088P Disease Disease P21359 L2164M Disease Neutral P21359 L847P Disease Disease P21359 K1444E Disease Disease P21359 L920P Disease Disease P21359 P678L Neutral Neutral P21359 L695P Disease Disease P21359 M1035R Disease Neutral P21359 L578R Disease Disease P21359 W784R Disease Disease P21359 Y1422H Neutral Neutral P21359 L357P Disease Disease P21359 T2507I Disease Neutral P21359 L1446P Disease Disease P21359 S82F Disease Neutral P21359 L508P Disease Neutral P21359 R1204G Disease Disease P21359 K1440R Disease Neutral P21359 L216P Disease Disease P21359 R1250P Disease Disease P21359 D186V Disease Disease P21359 L1953P Disease Disease P21359 T2631A Disease Neutral P21359 R1276Q Disease Disease P21359 N1156S Disease Disease P21359 W777S Disease Disease P21359 I1605V Disease Neutral P21359 G1166D Disease Disease P21359 L844P Disease Disease P21359 K583R Disease Neutral P21359 I117S Disease Disease P21359 E2357K Disease Neutral P21359 K1440Q Disease Neutral P21359 D176E Disease Neutral P21359 A1785S Disease Neutral P21359 H712R Disease Neutral P21359 Y2192N Disease Neutral P21359 S574R Disease Disease P21359 C93Y Disease Disease P21359 Y80C Neutral Disease P21359 R1611W Disease Disease P21359 R1204W Disease Disease P21359 M968R Disease Neutral P21359 Y489C Disease Neutral P21359 H781P Disease Neutral P21359 S1489G Disease Neutral P21359 I157N Disease Disease P21359 K1430E Disease Neutral P21359 H31R Disease Neutral P21359 L604V Disease Neutral P21359 I581T Disease Neutral P21359 A74D Disease Neutral P21359 R1276G Disease Disease P51946 V270A Neutral Neutral P51946 K138R Neutral Neutral P51946 R28L Neutral Neutral P51946 M54V Neutral Neutral Q6X4T0 P86S Neutral Neutral Q9UNP4 H48R Neutral Neutral Q6NSI4 I593M Neutral Neutral O60320 R375H Neutral Neutral O60320 G276D Neutral Neutral O60320 H393R Neutral Neutral Q6P1X5 S1122N Neutral Neutral Q6P1X5 P8L Neutral Neutral Q6P1X5 T1139A Neutral Neutral Q6P1X5 S447T Neutral Neutral Q495D7 I84V Neutral Neutral Q495D7 P38L Neutral Neutral Q495D7 A76E Neutral Disease Q9NWT8 Q107H Neutral Neutral P01562 A163G Neutral Disease P32881 E137K Neutral Disease Q9P0W0 E133K Neutral Neutral Q9P0W0 I97N Neutral Disease P01562 A137V Neutral Neutral P05014 A74T Neutral Disease P05014 V129M Neutral Neutral P05014 E137V Neutral Disease P01571 I184R Neutral Neutral P01566 G42A Neutral Neutral P05014 H49P Neutral Neutral P05000 R95S Neutral Neutral P01562 V10A Neutral Neutral Q6NZ36 P126S Neutral Neutral Q02833 R156Q Neutral Neutral Q02833 P89A Neutral Neutral Q96JS3 H806D Neutral Neutral Q96JS3 G244E Neutral Neutral Q96JS3 M592I Neutral Neutral Q96JS3 I678V Neutral Neutral Q96JS3 P256L Neutral Neutral Q96JS3 N398S Neutral Neutral Q96JS3 Q248E Neutral Neutral Q9NSG2 A481S Neutral Disease Q9HBJ7 E586K Neutral Neutral Q9HBJ7 N368S Neutral Neutral P01375 P84L Neutral Neutral P01375 A94T Neutral Disease P31939 T116S Neutral Neutral P31939 K426R Disease Disease Q9NUX5 V529M Neutral Neutral Q6P1S2 N160S Neutral Neutral Q6P1S2 A47T Neutral Neutral Q04941 A91S Neutral Neutral Q15149 R2110W Disease Neutral Q0VDD8 T220S Neutral Neutral Q0VDD8 P274L Neutral Neutral P30989 V304I Neutral Neutral Q8N699 R127G Neutral Neutral Q8N699 G119S Neutral Neutral Q7Z7H8 I125V Neutral Neutral Q8N1V2 E336K Neutral Disease Q5VWT5 I125M Neutral Neutral Q01118 I407V Neutral Neutral Q9BZG1 V197L Neutral Disease Q7Z4L5 A276T Neutral Neutral Q8NDW8 S1160R Neutral Neutral Q8NDW8 K1316R Neutral Neutral Q7Z4L5 M201V Neutral Neutral Q8NDW8 R719Q Neutral Neutral Q8NDW8 E293K Neutral Neutral Q7Z4L5 P463S Neutral Neutral Q8NDW8 V108L Neutral Neutral Q8NDW8 R1055L Neutral Disease Q8NDW8 R290K Neutral Neutral Q7Z4L5 K846R Neutral Neutral Q8NDW8 R91Q Neutral Neutral Q8NDW8 R622W Neutral Neutral Q7Z4L5 L473F Neutral Neutral Q9P0L9 R681L Neutral Neutral Q9P0L9 V393I Neutral Neutral P42773 A72P Disease Disease P42773 T126M Neutral Neutral Q9Y3Q0 V101I Neutral Neutral Q9Y3Q0 I446V Neutral Neutral Q14004 R700L Neutral Disease Q14004 T494A Neutral Neutral Q14004 V1170M Neutral Neutral Q14004 S624G Neutral Neutral Q14004 P356A Neutral Neutral Q14004 R410Q Neutral Neutral Q14004 T670R Neutral Neutral Q14004 L403F Neutral Neutral Q14004 V1062M Neutral Neutral Q14004 T500A Neutral Neutral Q6P6B7 A128G Neutral Neutral Q6P6B7 Q353R Neutral Disease Q10589 V143F Neutral Neutral Q10588 I101V Neutral Neutral Q10588 R145Q Neutral Neutral Q10588 A77V Neutral Neutral Q10588 R125H Neutral Neutral Q93100 A118P Disease Disease P35625 S179C Disease Disease P35625 G189C Disease Disease P35625 Y191C Disease Disease P35625 S204C Disease Neutral P35625 G190C Disease Disease P32930 Q20R Neutral Neutral Q96HC4 S136F Neutral Neutral Q13216 A160V Disease Disease Q13216 A205P Disease Disease Q13216 Y200C Neutral Disease Q96RS6 V269I Neutral Neutral Q96RS6 N426S Neutral Neutral Q96RS6 F252L Neutral Neutral Q96RS6 N394H Neutral Neutral P50402 Q133H Disease Neutral P50402 P183H Disease Neutral P50402 S54F Disease Neutral P50402 P183T Disease Neutral P50402 D149H Neutral Neutral O75409 V68I Neutral Neutral Q9NPI9 I11V Neutral Neutral Q4G0P3 T584N Neutral Neutral Q4G0P3 T690A Neutral Neutral Q4G0P3 R451P Neutral Disease Q4G0P3 N724D Neutral Neutral Q9GZR1 Y1106C Neutral Neutral Q9GZR1 R717P Neutral Disease Q9GZR1 E637K Neutral Neutral Q9GZR1 T121M Neutral Neutral Q96AQ8 T216A Neutral Neutral Q96AQ8 S108G Neutral Neutral P00505 V428A Neutral Disease P00505 G188S Neutral Disease P00505 G346V Neutral Neutral Q5T5Y3 A476V Neutral Neutral O43592 A526V Neutral Neutral O95568 A325V Neutral Neutral O95568 K360M Neutral Neutral O95568 E10D Neutral Neutral O60858 S355T Neutral Neutral Q9H081 M21V Neutral Neutral Q9UNA3 A218D Neutral Neutral Q13405 T9A Neutral Neutral P62861 V19M Neutral Neutral O60449 E268D Neutral Neutral O60449 D807E Neutral Neutral O60449 K486M Neutral Disease O60449 D884A Neutral Disease O60449 D692N Neutral Neutral O60449 K1347R Neutral Neutral O60449 H1391Y Neutral Neutral O60449 N1321K Neutral Disease O60449 T1202S Neutral Neutral Q86TI0 V228G Neutral Neutral Q86TI0 S14P Neutral Neutral Q86TI0 R1136Q Neutral Neutral Q86TI0 T55I Neutral Neutral Q86TI0 Y685S Neutral Disease Q3B820 E273K Neutral Neutral Q3B820 I236V Neutral Neutral Q9Y458 N264Y Disease Disease Q9Y458 P183L Disease Disease Q9Y458 M121V Disease Disease Q9Y458 T260M Disease Disease Q9Y458 G118C Disease Disease Q9Y458 L214P Disease Disease Q14203 A163P Neutral Neutral Q14203 G59S Disease Disease Q9GZV3 I89V Neutral Neutral Q8IZT6 R430G Neutral Neutral Q8IZT6 L3132R Neutral Neutral Q8IZT6 L2647I Neutral Neutral Q8IZT6 S2562G Neutral Disease O75054 Q1073R Neutral Neutral O75054 D1020E Neutral Neutral O75054 S51P Neutral Disease Q8NHP6 S240N Neutral Neutral P29376 R42Q Neutral Neutral Q9NRP2 T11S Neutral Neutral Q8TB61 L342V Neutral Neutral P55265 C966F Disease Disease P55265 L923P Disease Disease P55265 R1155W Disease Disease P55265 F1165S Disease Disease O60896 G26D Neutral Neutral O60896 W56R Neutral Disease Q86Z20 M13V Neutral Neutral Q4G176 V372M Neutral Neutral Q4G176 A17P Neutral Disease Q4G176 P2L Neutral Neutral P15313 P346R Disease Disease P15313 G316E Disease Disease P15313 L81P Disease Disease P15313 E161K Neutral Neutral P15313 M174R Disease Disease P15313 G364S Disease Neutral P15313 R157C Disease Disease P15313 T275P Disease Disease P15313 R465H Disease Disease P15313 R124W Disease Disease P15313 G123V Disease Disease P15313 T30I Neutral Neutral Q6AZZ1 C442Y Neutral Disease Q9C019 I29V Neutral Neutral Q86XT4 L8P Neutral Disease Q9BYJ4 T276S Neutral Neutral O00635 G421R Neutral Disease Q8NG06 V322I Neutral Neutral A6NDI0 L398M Neutral Neutral Q9C029 Q95E Neutral Disease Q86WT6 V31A Neutral Neutral P19474 G96R Neutral Disease Q9C035 R136Q Neutral Neutral Q9C035 H43Y Neutral Neutral Q8NG06 W3S Neutral Neutral Q9C035 V112F Neutral Disease P19474 E231K Neutral Disease Q9C035 P479L Neutral Disease Q9C029 P73S Neutral Neutral P19474 P52A Neutral Disease Q9C035 H419Y Neutral Neutral Q8NG06 T374M Neutral Neutral Q9C035 G249D Neutral Neutral Q9C029 A18S Neutral Neutral Q9BYJ4 D282H Neutral Neutral P14209 N173I Neutral Neutral P14209 M166V Neutral Neutral O75901 A285T Neutral Neutral Q5T8D3 T472M Neutral Neutral Q6NVY1 T46A Neutral Neutral Q6NVY1 Y122C Disease Disease Q8N573 K427R Neutral Neutral Q8N573 Q271P Neutral Neutral Q8N573 E11G Neutral Disease Q96FC9 I39S Neutral Disease Q96FC9 T575M Neutral Neutral Q96FC9 Q567E Neutral Neutral P19793 S336I Neutral Disease P62508 T50M Neutral Neutral P19793 P261L Neutral Disease Q68DQ2 Y761C Neutral Disease Q68DQ2 N926H Neutral Neutral Q68DQ2 R433H Neutral Neutral P61457 E97K Disease Disease P61457 R88Q Disease Disease P61457 T79I Disease Disease P61457 C82R Disease Disease O60285 G419D Neutral Neutral O60285 P543R Neutral Neutral O75711 P42L Neutral Disease P29460 V33I Neutral Neutral O95461 R665H Neutral Disease O95461 R68P Neutral Neutral O95461 E509K Disease Disease O95461 R68G Neutral Neutral Q96T60 Y196N Neutral Disease Q96T60 R180S Neutral Neutral Q96T60 P20S Neutral Neutral Q96T60 A63V Neutral Neutral Q96T60 V478G Neutral Disease O15321 R215H Neutral Neutral Q9P0X4 I1040V Neutral Neutral Q9P0X4 G1782R Neutral Neutral Q9P0X4 G1782A Neutral Neutral Q8N999 V238L Neutral Neutral Q8N999 P23L Neutral Neutral Q16850 V13A Neutral Neutral Q5T124 E165G Neutral Neutral Q5T124 L312R Neutral Neutral Q5T124 A474V Neutral Neutral Q5JX71 V66A Neutral Neutral Q5JX69 E129A Neutral Neutral Q5JX71 R146K Neutral Neutral Q5JX71 M117K Neutral Neutral Q5JX71 R135G Neutral Neutral Q5JX71 L95F Neutral Neutral P07476 V480L Neutral Neutral P07476 L166P Neutral Neutral P07476 T113A Neutral Neutral P07476 K174E Neutral Neutral P07476 E237Q Neutral Neutral P07476 Q312K Neutral Neutral Q8IVV8 K91Q Neutral Neutral Q8IVV8 A131D Neutral Disease Q8IVV8 E173D Neutral Neutral Q8IVV8 C151G Neutral Neutral Q6NTE8 Q97R Neutral Neutral Q6NTE8 Q231R Neutral Neutral Q6NTE8 G154R Neutral Neutral Q9NRG0 H126R Neutral Neutral Q9NRG0 C55Y Neutral Neutral Q5FWF4 E541K Neutral Neutral Q5FWF4 R546Q Neutral Neutral Q8NA69 L500P Neutral Neutral Q8NA69 Y434N Neutral Disease Q8NA69 Y396N Neutral Neutral Q8NA69 D256G Neutral Neutral Q8NA69 P497S Neutral Neutral P23025 C108F Disease Disease P23025 H244R Disease Disease P23025 R130K Disease Neutral P23025 V97I Neutral Neutral P23025 Q185H Disease Disease P23025 V234L Neutral Neutral P23025 L252V Neutral Neutral P23025 P94L Disease Neutral P23025 R228Q Neutral Neutral P08603 C1163W Disease Disease P08603 C536R Disease Disease P08603 F1199S Disease Disease P08603 S890I Neutral Neutral P08603 I1059T Neutral Neutral P08603 C673S Disease Disease P08603 D1119G Disease Neutral P08603 V62I Neutral Neutral P08603 W1183R Disease Disease P08603 H893R Disease Neutral P08603 W1157R Disease Disease P08603 P1226S Disease Disease P08603 Q400K Disease Disease P08603 W978C Disease Disease P08603 R1210C Disease Neutral P08603 S1191L Disease Neutral P08603 E1198A Disease Neutral P08603 C431S Disease Disease P08603 C959Y Disease Disease P08603 N1050Y Neutral Neutral P08603 E850K Disease Disease P08603 C630W Disease Disease P08603 I551T Neutral Disease P08603 L1189R Disease Disease P08603 Y1021F Disease Neutral P08603 C673Y Disease Disease P08603 C915S Disease Disease P08603 V1007I Neutral Neutral P08603 G1194D Disease Disease P08603 V1197A Disease Disease P08603 T1017I Neutral Neutral P08603 V1134G Disease Disease P08603 Q1076E Disease Neutral P08603 R78G Disease Disease P08603 W1183L Disease Disease P08603 Y951H Disease Neutral P08603 C1043R Disease Disease P08603 Q950H Disease Neutral P08603 R1215G Disease Disease P08603 T1184R Disease Neutral P08603 Y402H Neutral Neutral P08603 R127L Disease Disease P08603 E936D Neutral Neutral P08603 Y1142D Disease Disease P08603 T956M Disease Neutral P08603 R1215Q Disease Neutral Q6GTS8 G346R Neutral Disease Q6GTS8 R153W Neutral Disease Q6GTS8 V149I Neutral Neutral Q6GTS8 I237T Neutral Disease Q6GTS8 I380T Neutral Neutral Q6GTS8 H33Y Neutral Neutral Q6GTS8 S258C Neutral Disease Q99848 R223H Neutral Neutral P20839 V268I Disease Neutral P20839 R224P Disease Disease P20839 D226N Disease Disease P56589 G138E Disease Disease O14594 P92S Neutral Neutral O14594 A70T Neutral Neutral O14594 A1254V Neutral Neutral P28039 A166T Neutral Neutral P28039 A266G Neutral Neutral Q15053 Q26K Neutral Neutral Q9H0A6 H291Q Neutral Neutral Q9H0A6 R307C Neutral Neutral Q9H0A6 R288Q Neutral Neutral O75326 R461C Neutral Disease O75326 R460H Neutral Disease O75326 S115T Neutral Neutral O75326 R207Q Neutral Neutral O75326 R207W Neutral Disease O15194 V132G Neutral Disease O15194 N127S Neutral Neutral O15194 S121P Neutral Disease O14578 R9Q Neutral Neutral O14578 G7E Neutral Neutral O14578 L183F Neutral Neutral Q9H649 A295V Neutral Neutral Q969Z3 G244S Neutral Disease Q5VT66 M187K Neutral Disease Q5VT66 C246S Neutral Disease Q5VT66 M268I Neutral Disease Q5VT66 T165A Neutral Neutral O60930 L4F Neutral Neutral Q9UL17 H33Q Neutral Neutral Q9UL17 I339V Neutral Neutral Q9H6Y5 R53H Neutral Neutral Q96EU7 E152K Disease Disease Q96EU7 D131E Neutral Neutral O43829 Q139R Neutral Neutral O43829 E77G Neutral Neutral Q9Y619 I254L Neutral Neutral O43772 Q238R Disease Disease O43772 D231H Disease Disease Q9BXI2 I226V Neutral Neutral Q9Y619 G27E Disease Disease Q9Y619 G27R Disease Disease Q8N413 M224V Neutral Neutral Q9Y619 P126R Disease Disease Q9Y619 G190D Disease Neutral Q9Y619 E180K Disease Neutral Q9BXI2 G159C Neutral Disease Q9BXI2 G181V Neutral Neutral O43772 R133W Disease Disease Q9Y619 R275Q Disease Disease P07498 A145T Neutral Neutral P07498 R110L Neutral Disease P07498 Y75C Neutral Neutral Q6PID6 L69M Neutral Neutral Q86T90 R383C Neutral Neutral Q8TER0 L1228P Neutral Neutral Q8TER0 A1362S Neutral Neutral Q8TER0 H1299R Neutral Neutral Q8TER0 R1289Q Neutral Neutral P52630 Q826H Neutral Neutral P52630 M594I Neutral Neutral P52630 I464V Neutral Neutral P52630 T448M Neutral Disease P52630 L220P Neutral Disease P52630 Q66H Neutral Neutral P52630 S501I Neutral Disease Q5TAA0 L14V Neutral Neutral Q5T5N4 I256M Neutral Neutral Q5T5N4 V363L Neutral Neutral Q9BXX2 F477L Neutral Neutral Q9BXX2 V375M Neutral Neutral P05089 G138V Disease Disease P05089 T290S Neutral Neutral P05089 I11T Disease Neutral P05089 G235R Disease Disease Q96AZ1 S28L Neutral Neutral Q6PK18 D67E Neutral Neutral Q6PK18 P272R Neutral Neutral Q6ZVW7 L333P Neutral Neutral P49247 A135V Disease Neutral Q9Y4C8 A665T Neutral Neutral Q9Y4C8 T623I Neutral Neutral Q9Y4C8 R609H Neutral Neutral Q9Y4C8 R921Q Neutral Neutral Q15545 S178R Neutral Disease P20711 M239L Neutral Neutral P20711 P210L Neutral Disease P20711 G102S Disease Neutral P20711 E61D Neutral Neutral P20711 R462Q Neutral Neutral P20711 M217V Neutral Disease P20711 M239I Neutral Disease P20711 V17M Neutral Disease Q7RTP6 M778L Neutral Neutral Q9H3H1 F202L Neutral Neutral Q96PD7 R317G Neutral Disease Q96PD7 M361I Neutral Neutral O75718 E137D Neutral Neutral Q13263 T794M Neutral Neutral Q86Y22 T287A Neutral Neutral O43315 A279T Neutral Neutral Q9NUW8 H493R Disease Disease Q9NUW8 E95D Neutral Neutral Q9NUW8 R304Q Neutral Neutral Q9NUW8 A134T Neutral Neutral Q9NUW8 D187G Neutral Disease Q9NUW8 T569A Neutral Neutral Q9NUW8 P101L Neutral Neutral O00254 N250D Neutral Neutral O00254 L15S Neutral Neutral O00254 M177V Neutral Neutral P34059 P179H Disease Disease P34059 F69V Disease Neutral P34059 H401Y Disease Disease P34059 F452I Disease Neutral P34059 G47R Disease Disease P34059 H150Y Disease Neutral P34059 E185G Disease Neutral P34059 G155E Disease Disease P34059 R386H Disease Disease P34059 S341R Disease Disease P34059 K310N Disease Disease P34059 I113F Disease Disease P34059 L15M Disease Neutral P34059 D60N Disease Disease P34059 P357L Disease Neutral P34059 F346L Disease Neutral P34059 P125L Disease Disease P34059 D344E Disease Disease P34059 H166Q Disease Neutral P34059 V239F Disease Neutral P34059 R253W Disease Disease P34059 S53F Disease Disease P34059 G96V Disease Disease P34059 G116S Disease Disease P34059 D233N Disease Neutral P34059 A257T Disease Neutral P34059 N407H Disease Neutral P34059 A203V Disease Neutral P34059 A291D Disease Disease P34059 L307P Disease Disease P34059 E450V Disease Disease P34059 P151S Disease Disease P34059 F156C Disease Disease P34059 L352P Disease Disease P34059 W325C Disease Disease P34059 E260D Disease Disease P34059 L67M Disease Neutral P34059 T312S Disease Neutral P34059 G340D Disease Neutral P34059 R380S Disease Disease P34059 M391V Disease Disease P34059 G23R Disease Disease P34059 M343R Disease Disease P34059 M41L Disease Disease P34059 P179L Disease Disease P34059 Q111R Disease Neutral P34059 R94L Disease Disease P34059 W409S Disease Disease P34059 G247D Disease Neutral P34059 L36P Disease Disease P34059 G96C Disease Disease P34059 R94C Disease Disease P34059 F167V Disease Neutral P34059 R376Q Disease Neutral P34059 D171A Disease Neutral P34059 S80L Disease Disease P34059 R259Q Disease Neutral P34059 R94G Disease Disease P34059 P77R Disease Neutral P34059 H398D Disease Disease P34059 W230G Disease Neutral P34059 S135R Disease Disease P34059 F156S Disease Disease P34059 L395P Disease Disease P34059 N164T Disease Neutral P34059 G42E Disease Disease P34059 P484S Disease Neutral P34059 G301C Disease Disease P34059 F284V Disease Neutral P34059 P179S Disease Disease P34059 C79Y Disease Disease P34059 S470P Disease Disease P34059 W141C Disease Disease P34059 G168R Disease Neutral P34059 S162F Disease Neutral P34059 P151L Disease Neutral P34059 M494V Disease Neutral P34059 G290S Disease Disease P34059 A392V Disease Disease P34059 R90W Disease Disease P34059 R361G Disease Disease P34059 M318R Disease Disease P34059 S295F Disease Disease P34059 W141R Disease Disease P34059 R386C Disease Disease P34059 R61W Disease Disease P34059 S287L Disease Disease P34059 L395V Disease Neutral P34059 L345P Disease Disease P34059 G155R Disease Disease P34059 A291T Disease Disease P34059 V138A Disease Disease P34059 R380T Disease Disease P34059 N204K Disease Disease P34059 L369P Disease Disease P34059 D388N Disease Neutral P34059 D344N Disease Disease P34059 G139S Disease Disease P34059 G309R Disease Disease P34059 A351V Disease Neutral P34059 F97V Disease Neutral P34059 A107T Disease Neutral P34059 N487S Disease Neutral P13647 E190K Disease Disease P35527 L458F Disease Disease P35908 E482V Disease Disease P13647 D328H Disease Disease Q14533 G52R Neutral Disease P08779 M121T Disease Disease P35527 M157R Disease Disease P13647 I467T Disease Disease P35527 M157V Disease Disease Q6A162 T37A Neutral Neutral P13645 K439E Disease Disease P14136 R79H Disease Disease P04264 K74I Disease Disease Q6A162 T153M Neutral Neutral P13647 S181P Disease Disease P08727 G60A Neutral Neutral O43790 N114D Disease Disease P17661 S2I Disease Neutral P17661 K449T Disease Disease P04264 G537C Neutral Neutral P17661 E245D Disease Disease P08779 L124R Disease Disease O95678 P117A Neutral Neutral P13647 R352S Disease Neutral Q2M2I5 M267I Neutral Disease Q5XKE5 A393V Neutral Neutral Q7RTS7 N165K Neutral Disease P13646 L119P Disease Disease P35908 L490P Disease Disease P04264 V155G Disease Disease Q14533 R316C Neutral Disease P35908 I188N Disease Disease P02533 R211P Disease Disease P08779 R127P Disease Disease Q04695 L95Q Disease Disease P13646 M108T Disease Disease O95678 E242G Neutral Disease Q14533 E402K Disease Disease P35908 E493D Disease Disease P02533 A247D Disease Disease P13647 D328V Disease Disease Q8N1N4 L92P Neutral Disease Q6A162 S102N Neutral Disease Q04695 M88T Disease Disease Q6A163 T341M Neutral Neutral P35908 E471K Disease Disease Q99456 Y429D Disease Neutral P02533 Y129D Disease Disease P14136 D295N Neutral Neutral P02533 D273G Disease Disease P14136 E223Q Disease Neutral P13645 M150R Disease Disease P02533 R417P Disease Disease P35527 V171M Disease Disease Q2M2I5 R366C Neutral Disease P13645 R156P Disease Disease P35527 L160F Disease Disease P13645 M150T Disease Disease P13647 L325P Disease Disease Q04695 Y98D Disease Disease Q99456 Q130P Disease Disease P13647 K404E Disease Neutral P13647 P25L Disease Neutral P02533 L419Q Disease Disease P13647 A438D Disease Disease P05783 G340R Disease Disease P04264 L214P Disease Disease Q99456 L140R Disease Disease P02533 M272T Disease Disease P02533 K116N Disease Disease Q04695 N92S Disease Disease P04264 N358Y Neutral Neutral O76013 T315M Neutral Neutral P05787 G62C Disease Disease P04259 S227N Neutral Neutral P12035 R503P Disease Disease P13645 G126S Neutral Neutral P14136 R416W Disease Disease P13647 K173N Disease Disease P13647 D328G Disease Neutral P02533 A94T Neutral Neutral Q99456 I426S Disease Disease P13647 D158V Disease Disease P02538 N21S Neutral Neutral P02533 E144A Disease Neutral P13646 L111P Disease Disease P14136 A244V Disease Neutral P13647 V323A Disease Disease P04264 D340V Disease Disease Q2M2I5 K429E Neutral Neutral P02533 Y415C Disease Neutral P02533 N123S Disease Disease P08779 K354N Disease Disease P17661 L385P Disease Disease P35527 N161K Disease Disease P02533 A413T Disease Neutral Q14533 E413K Disease Disease P13647 K199T Disease Neutral P17661 T442I Disease Neutral Q99456 R135I Disease Disease P04264 R633K Neutral Neutral P35527 R163Q Disease Disease P02533 M272R Disease Disease O95678 A161T Neutral Disease P17661 R355P Disease Disease P35908 N192D Disease Disease Q9NSB2 G497R Neutral Neutral Q7RTS7 E271D Neutral Disease Q14CN4 R428L Neutral Disease P08729 A364G Neutral Neutral P13647 R169P Disease Disease P17661 S46F Disease Disease P08779 Q122P Disease Disease P02533 R134P Disease Disease P13647 E167K Disease Disease P13647 T469P Disease Disease Q99456 R135S Disease Disease O43790 E402Q Disease Disease P13647 S79R Neutral Neutral P13647 M327T Disease Disease P14136 R239H Disease Disease P02533 V133A Neutral Disease P02533 A274D Disease Disease O95678 R39C Neutral Disease P04259 N21S Neutral Neutral P13645 L161S Disease Disease O43790 E413K Disease Disease P04264 S186P Disease Disease P04264 N188S Disease Disease Q9NSB2 R184Q Neutral Disease P13647 E477K Disease Disease P17661 N393I Disease Disease P13647 V186L Disease Disease P02533 R416P Disease Disease P13646 N112S Disease Disease P48668 S227N Neutral Neutral P02533 R125S Disease Disease P78385 C149R Neutral Disease P14136 R88S Disease Disease P04259 V365I Neutral Neutral P13647 Q191P Disease Disease Q99456 V143L Disease Disease P13647 F179S Disease Disease Q9NSB4 T458M Neutral Neutral P02538 F174V Disease Disease P17661 R350P Disease Disease P04259 E472K Disease Disease P13645 N154H Disease Disease P35908 E494K Disease Disease Q3SY84 R523Q Neutral Neutral Q14CN4 D366E Neutral Neutral P13647 P152L Disease Disease O95678 G91R Neutral Disease P12035 E509K Disease Disease P35527 L160V Disease Disease P17661 A213V Disease Neutral Q6A163 R456Q Neutral Neutral P13647 N329K Disease Disease P04264 N188T Disease Disease P04264 S193P Disease Disease Q13515 R287W Disease Disease Q3SY84 E122K Neutral Disease O43790 N114H Disease Disease Q9C075 T303A Neutral Neutral Q9NSB2 S198N Neutral Disease P13647 S528G Neutral Neutral P08779 L128Q Disease Disease P05787 G53V Disease Disease P02533 M119T Disease Disease P02533 L122F Disease Disease P17661 R406W Disease Disease Q99456 R135G Disease Disease P13647 D328E Disease Neutral Q9NSB4 E219Q Neutral Disease P17661 A337P Disease Disease P17661 Q389P Disease Disease P02538 E472K Disease Disease P13647 I161S Disease Disease P13647 G138E Neutral Disease Q9NSB2 R446C Neutral Disease Q9NSB2 I206V Neutral Neutral P02533 L143P Disease Disease Q99456 R20W Neutral Neutral Q04695 R94C Disease Disease P02533 R125C Disease Disease P08779 N125S Disease Disease P17661 K449M Disease Disease P08779 R127C Disease Disease P13645 Y160D Disease Disease P78385 Y493H Neutral Neutral Q8N1N4 A238T Neutral Neutral P13647 R331H Disease Disease Q2M2I5 G250D Neutral Disease P13645 R422E Disease Disease Q99456 A137P Disease Disease P04264 V155D Disease Disease P13647 S387T Neutral Neutral P48668 R182Q Neutral Disease P17661 I451M Disease Disease P04264 N188K Disease Disease P17661 R454W Disease Neutral P35527 R163W Disease Disease P78385 M279I Neutral Neutral P13645 L442Q Disease Disease P13647 R331C Disease Neutral P35908 E471D Disease Neutral P04264 Y482C Disease Neutral P14136 R88C Disease Disease Q8N1N4 R25H Neutral Neutral P02533 R125H Disease Disease P13647 V143D Disease Disease P13647 L175F Disease Disease P14136 R239C Disease Disease Q2M2I5 C415Y Neutral Disease P02533 R148C Disease Disease Q3SY84 I355F Neutral Disease P14136 P47L Disease Neutral Q14CN4 Y264C Neutral Disease P02533 R388H Disease Disease P08779 L132P Disease Disease P35527 M157T Disease Disease P02533 R125G Disease Disease P02533 L384P Disease Disease P14136 R79C Disease Disease Q99456 Y429C Disease Neutral P35527 N161H Disease Disease P02533 L130P Disease Disease O76013 A119V Neutral Neutral Q99456 M129T Disease Disease P13647 E475G Disease Disease P17661 A357P Disease Disease P04264 L161P Disease Disease P02533 L408M Disease Disease P14136 E362D Disease Disease P05783 S230T Neutral Neutral P19013 E449K Disease Disease P14136 R258P Disease Disease O95678 E337K Disease Disease Q04695 N109D Disease Disease P78385 E407K Disease Disease P02533 Y415H Disease Neutral P35527 L168S Disease Disease P35908 I483N Disease Disease P02533 E422K Disease Disease P13647 G517D Disease Neutral P13647 V186M Disease Disease Q04695 N92D Disease Disease P13645 Y160S Disease Disease P13647 L311P Disease Disease O95678 R485S Neutral Neutral P04264 A454S Neutral Neutral Q04695 R94H Disease Disease P35908 N192Y Disease Disease P19013 A72V Neutral Neutral P13647 N176S Disease Disease Q14CN4 N171D Neutral Neutral P13647 S232N Neutral Neutral P17661 N342D Disease Disease P17661 L370P Disease Disease P02533 R388C Disease Disease P48668 V481I Neutral Neutral P35527 R163P Disease Disease P02533 Q120R Disease Disease Q04695 L95P Disease Disease P05783 T103A Disease Neutral P04264 I312V Neutral Neutral P02533 N123K Disease Disease P17661 S460I Disease Disease P13646 L115P Disease Disease Q5XKE5 S81L Neutral Disease P05783 H128L Disease Neutral P35908 E482K Disease Disease O76013 Q126R Neutral Neutral P13647 M327K Disease Disease P13647 E168K Disease Disease Q04695 L99P Disease Disease Q3SY84 G464V Neutral Disease Q6A163 L383M Neutral Neutral O43790 E402K Disease Disease P13647 N177S Disease Neutral P14136 D78E Disease Disease O95678 M427T Neutral Disease Q04695 N92H Disease Disease P04264 E490Q Disease Neutral P04264 I330T Neutral Disease P02533 M119V Disease Disease P35908 N192K Disease Disease P17661 A360P Disease Disease P02533 V133L Disease Neutral Q14533 R248L Neutral Neutral Q5XKE5 H266R Neutral Disease Q04695 V102M Disease Disease P17661 L345P Disease Disease O95678 I367V Neutral Neutral P35527 N161I Disease Disease P05787 I63V Neutral Neutral P78386 R78H Disease Neutral P13645 I446T Disease Disease P04264 L486P Disease Disease P14136 L76F Disease Disease P13647 G543S Neutral Neutral P02533 I377N Disease Disease O43790 E413D Disease Neutral P02538 G111D Neutral Neutral P13645 R156C Disease Disease P05787 Y54C Disease Disease P13647 V324D Disease Disease P04264 I479F Disease Disease P35908 T485P Disease Disease P17661 S46Y Disease Neutral P13647 L463P Disease Disease P13645 Y160N Disease Disease Q9NSB4 E452D Neutral Neutral O95678 R432C Neutral Disease P13645 R156S Disease Disease Q2M2I5 W418R Neutral Neutral O95678 R209Q Neutral Neutral P35908 E493K Disease Disease Q3SY84 V107I Neutral Neutral P13647 E170K Disease Disease P13647 D197E Neutral Neutral Q99456 R135T Disease Disease P02533 V270M Disease Disease P13647 E418K Disease Disease P35908 Q187P Disease Disease P04264 I479T Disease Disease P35527 N161Y Disease Disease P13647 N193K Disease Disease P35527 Q172P Disease Disease P13645 R156H Disease Disease P14136 N77Y Disease Disease P05783 R261Q Disease Neutral P35527 N161S Disease Disease P13646 A146G Neutral Neutral P13647 E475K Disease Disease Q8N1N4 G224A Neutral Neutral Q5XKE5 F195L Neutral Disease P02538 L469R Disease Disease Q6A162 F85S Neutral Disease Q2M2I5 A115T Neutral Neutral Q04695 R94P Disease Disease Q9Y6B6 G37R Disease Disease Q9Y6B6 D137N Disease Disease Q9Y6B6 S179R Disease Disease P20333 L264P Neutral Disease P20333 Q295R Neutral Neutral P20333 T269P Neutral Neutral P20333 P301R Neutral Neutral P20333 M196R Neutral Neutral P20333 V187M Neutral Neutral P20333 E232K Neutral Neutral P20333 A236T Neutral Neutral Q8IXB3 G57S Neutral Neutral Q8IXB3 A18T Neutral Neutral Q8IXB3 P15S Neutral Neutral Q8IXB3 H3Y Neutral Neutral Q8IXB3 E34D Neutral Neutral Q8IXB3 S20F Neutral Neutral Q01970 R483H Neutral Neutral Q5SV97 W20R Neutral Neutral Q6NXP0 E66G Neutral Neutral Q6NXP2 P112T Neutral Neutral Q6NXP2 V114D Neutral Neutral Q6NXP2 I251V Neutral Neutral Q6NXP2 R136W Neutral Disease Q69YN4 I753V Neutral Neutral Q9NWS8 T132M Neutral Neutral Q5T013 D239N Neutral Neutral Q6P387 Y335H Neutral Neutral Q6P387 K357E Neutral Neutral Q6P387 P388S Neutral Neutral Q6P387 I288T Neutral Neutral Q6P387 T77S Neutral Neutral Q15849 A880T Neutral Neutral Q6PI73 L69W Neutral Neutral Q6PI73 Y400H Neutral Neutral Q8N149 H25N Neutral Neutral Q6PI73 G149R Neutral Disease Q6PI73 P288R Neutral Neutral Q8N149 H25L Neutral Neutral Q99527 P16L Neutral Neutral Q4VX76 P414S Neutral Disease Q4VX76 Q587L Neutral Neutral Q4VX76 V540I Neutral Neutral P05231 D162V Neutral Neutral P05231 D162E Neutral Neutral P05231 P32S Neutral Neutral O15111 V155A Neutral Neutral O15111 S126C Neutral Neutral O15111 I268V Neutral Neutral Q9BZZ5 M300V Neutral Neutral Q9BZZ5 P276S Neutral Neutral Q9BZZ5 G493S Neutral Neutral Q9BZZ2 A974V Neutral Neutral Q9BZZ2 V221M Neutral Disease Q9BZZ2 S1335Y Neutral Disease Q9BZZ2 H919P Neutral Disease Q9BZZ2 K239R Neutral Neutral Q9BZZ2 A1519P Neutral Disease O95971 I91V Neutral Neutral O43665 A94V Neutral Disease Q92574 H732Y Disease Neutral Q92574 E51D Disease Neutral Q92574 L191H Disease Disease Q92574 S829R Neutral Neutral Q92574 Q654E Disease Neutral Q92574 T417I Disease Neutral Q92574 G1035S Neutral Neutral Q92574 T899S Disease Neutral Q92574 G1108S Neutral Neutral Q92574 M322T Neutral Neutral Q92574 K587R Disease Neutral Q92574 R190S Neutral Disease Q92574 E577D Neutral Neutral Q92574 M224R Disease Neutral Q92574 E809Q Neutral Neutral Q92574 A726E Disease Disease O75581 S817C Neutral Disease O75197 A242T Disease Disease O75197 V1204L Neutral Neutral O75197 E1367K Disease Disease O75197 Q89R Neutral Neutral O75581 V483I Neutral Neutral O75581 R611C Disease Disease O75197 G171V Disease Disease O75197 C1361G Disease Disease O75197 A214T Disease Disease O75197 V667M Neutral Neutral O75197 R570W Disease Disease O75197 R570Q Disease Disease O75197 R494Q Disease Disease O75197 R752C Disease Disease O75581 R1401H Neutral Neutral O75197 A1330V Neutral Disease O75197 A1525V Neutral Neutral O75581 I1062V Neutral Neutral O75197 T253I Disease Disease O75197 D111Y Disease Neutral O75197 G171R Disease Disease Q9UG01 R953H Neutral Neutral Q96RP9 N174S Disease Disease Q96RP9 V215I Neutral Neutral Q96RP9 M496R Disease Disease Q03154 E233D Disease Neutral Q9NZH7 R36C Neutral Neutral O14777 E348D Neutral Neutral O14777 A605P Neutral Neutral O14777 S66A Neutral Neutral P78410 N181D Neutral Neutral Q02388 G2028A Disease Neutral Q02388 G2009R Disease Disease Q02388 G2775S Disease Disease Q02388 G2034W Disease Disease Q02388 G2132D Disease Disease Q02388 R2063W Disease Neutral Q02388 G2674R Disease Disease Q02388 G2749R Disease Disease Q02388 G1703E Disease Disease Q02388 G2015E Disease Disease Q02388 G2049E Disease Disease Q02388 G2348R Disease Disease Q02388 G2043W Disease Disease Q02388 G2287R Disease Disease Q02388 G1604R Disease Disease Q02388 G1782R Disease Disease Q02388 R1772W Disease Neutral Q02388 G2674D Disease Disease Q02388 P595L Disease Disease Q02388 R2791W Disease Disease Q02388 G1347R Disease Disease Q02388 K142R Disease Neutral Q02388 G2351R Disease Disease Q02388 G2006D Disease Disease Q02388 G2740A Disease Disease Q02388 P1277L Disease Neutral Q02388 G2316R Disease Disease Q02388 G1982W Disease Disease Q02388 G2569R Disease Disease Q02388 G2653R Disease Disease Q02388 G2034R Disease Disease Q02388 G2028R Disease Disease Q02388 G1776R Disease Disease Q02388 G2713R Disease Disease Q02388 G1519D Disease Disease Q02388 G2031S Disease Disease Q02388 G2076D Disease Disease Q02388 G2064R Disease Disease Q02388 G2192S Disease Disease Q02388 R2008G Disease Neutral Q02388 G2043R Disease Disease Q02388 G1522E Disease Disease Q02388 G2242R Disease Disease Q02388 G2263V Disease Disease Q02388 G1791E Disease Disease Q02388 G2369S Disease Disease Q02388 G1812R Disease Disease Q02388 G2040V Disease Disease Q02388 G2025A Disease Disease Q02388 G2623C Disease Disease Q02388 G2073D Disease Disease Q02388 G2079R Disease Disease Q02388 G2251E Disease Disease Q02388 G2037E Disease Disease Q02388 G2207R Disease Disease Q02388 G2575R Disease Disease Q02388 G2003R Disease Disease Q02388 G2079E Disease Disease Q02388 M2798K Disease Disease Q02388 P2429L Neutral Neutral Q02388 G2006A Disease Disease Q02388 G2046V Disease Disease Q02388 G2055E Disease Disease Q02388 G2040D Disease Disease Q02388 G2713D Disease Disease Q02388 G1652R Disease Disease Q02388 G1557R Disease Disease Q02388 G2040S Disease Disease Q02388 R2008C Disease Neutral Q02388 G2366S Disease Disease Q02388 G2671V Disease Disease Q8IU85 I66M Neutral Neutral Q53S99 E104Q Neutral Neutral O14901 T220M Disease Neutral O14901 A347S Disease Neutral O75030 S357P Disease Disease O75030 S405P Disease Neutral O75030 N317K Disease Disease O75030 R310K Disease Disease O75030 N385D Disease Disease Q8NE79 R129W Neutral Neutral Q9P265 I792V Neutral Neutral P57678 R1033C Neutral Neutral P57678 R684Q Neutral Neutral P57678 A579G Neutral Neutral Q7LBC6 S1201N Neutral Neutral Q7LBC6 T256A Neutral Neutral O95573 F551S Neutral Neutral O60488 R570S Disease Disease Q8N3J3 T126P Neutral Neutral Q5K651 I143T Neutral Neutral Q8IVG5 N1516T Neutral Neutral Q8IVG5 V266I Neutral Neutral Q5K651 V549L Neutral Neutral Q5K651 K1495E Disease Neutral Q5K651 N449S Neutral Neutral Q8IVG5 F289S Neutral Disease Q8IVG5 G1137A Neutral Neutral Q8IUH8 S601P Neutral Neutral Q8IUH8 R123Q Neutral Neutral Q8IUH8 P643R Neutral Neutral Q8IUH8 H303R Neutral Neutral Q8IUH8 R461P Neutral Disease Q8IUH8 I471V Neutral Neutral Q8IUH8 G620R Neutral Neutral Q06418 A831T Neutral Neutral Q5T4W7 Q19R Neutral Neutral P09681 N146S Neutral Neutral P09681 S103G Neutral Neutral Q6UXX9 L186P Neutral Neutral Q9UIG4 P84L Neutral Neutral Q9UIG4 G25D Neutral Neutral Q9BUZ4 A173T Neutral Neutral P01241 T201A Disease Disease P01241 L16P Disease Disease P01241 K67R Disease Neutral P01241 D138G Disease Disease P01242 R90W Neutral Disease P01241 T53I Disease Disease P01241 R103C Disease Disease P01241 R42C Disease Disease P01241 S105C Neutral Disease P01243 P3A Neutral Neutral P01241 V136I Neutral Neutral P01241 N73D Disease Neutral P01241 E100K Disease Neutral P01241 T3A Disease Neutral P01241 I205M Disease Neutral P01241 C79S Disease Disease P01241 Q117L Disease Disease P01241 S97F Disease Disease P01241 S134C Disease Disease P01241 S134R Disease Disease P01241 R209H Disease Disease P01241 D37N Disease Disease Q9HDC9 I65V Neutral Neutral P21912 C101Y Disease Disease P21912 R242H Disease Disease P21912 C192R Disease Disease P21912 S100F Disease Disease P21912 R46G Disease Disease P21912 L87S Disease Disease P21912 H132P Disease Disease P21912 C196Y Disease Disease P12724 T124R Neutral Neutral Q9H1E1 Y116H Neutral Disease P12724 R72C Neutral Disease P12724 G130R Neutral Neutral P03950 K84E Neutral Disease P34096 T16S Neutral Neutral Q9H1E1 P103A Neutral Neutral Q93091 R89Q Neutral Neutral A6NEQ2 R367P Neutral Neutral A6NEQ2 V186L Neutral Neutral Q9BTX1 G154D Neutral Neutral Q9H3Y0 F15C Neutral Neutral Q86Y07 I167V Neutral Neutral Q86Y07 I157M Neutral Neutral Q86Y07 N50D Neutral Neutral P42704 A354V Disease Neutral Q92482 V43M Neutral Disease Q96PS8 R15Q Neutral Disease Q9BYV9 A418T Neutral Neutral Q86W92 V148L Neutral Neutral Q7Z5J4 P165T Neutral Neutral Q6PKC3 V783L Neutral Neutral Q9H116 Q275P Neutral Disease Q7Z5L2 H656R Neutral Neutral Q7Z5L2 H566R Neutral Neutral Q8IV03 S62G Neutral Neutral P13473 P256H Neutral Disease P13473 W321R Disease Neutral P49720 M34L Neutral Neutral Q96C92 R304Q Neutral Disease Q96C92 E176G Neutral Neutral Q96C92 L157V Neutral Neutral Q96C92 V379M Neutral Neutral Q96C92 V428I Neutral Neutral Q92902 G283W Neutral Neutral Q92902 E100D Neutral Neutral Q92902 Q603R Neutral Neutral Q92902 P491R Neutral Neutral Q92902 V630I Neutral Neutral Q92902 A186V Neutral Neutral Q92902 A480T Neutral Neutral P38435 R485P Disease Disease P38435 G558R Disease Disease P38435 R325Q Neutral Neutral P38435 W501S Disease Disease P38435 F299S Disease Disease P38435 W493S Disease Disease P38435 L394R Disease Disease P38435 R476C Disease Disease P38435 R476H Disease Disease Q8WYP5 N883S Neutral Neutral Q8WYP5 L2194V Neutral Neutral Q8N1F1 S78T Neutral Neutral Q8N1F1 Y36C Neutral Neutral Q8IV63 S59F Neutral Neutral Q8IV63 R370C Neutral Disease Q8IV63 S268L Neutral Neutral Q8IV63 C288Y Neutral Disease Q8IV63 S371G Neutral Neutral Q8IV63 F171L Neutral Neutral Q8IV63 P105T Neutral Neutral Q7Z5J8 F1077L Neutral Neutral Q7Z5J8 I675V Neutral Neutral Q9NST1 K434E Neutral Neutral Q9NST1 I148M Neutral Disease Q9NST1 C99G Neutral Neutral Q9NST1 G115C Neutral Neutral Q86YV5 C578S Neutral Neutral Q86YV5 V1041M Neutral Neutral Q86YV5 P814L Neutral Neutral Q86YV5 P662T Neutral Neutral Q86YV5 Q404R Neutral Neutral Q86YV5 R1315H Neutral Disease Q86YV5 R137G Neutral Neutral Q86YV5 P595A Neutral Neutral Q86YV5 V139I Neutral Neutral Q86YV5 T1113A Neutral Neutral Q86YV5 S1003L Neutral Neutral Q86YV5 L122I Neutral Neutral Q86YV5 H851R Neutral Neutral Q86YV5 L569P Neutral Neutral P09104 P264A Neutral Neutral P09104 T395A Neutral Disease P13929 V85A Neutral Neutral P06733 N177K Neutral Disease P13929 N71S Neutral Neutral Q93070 T189M Neutral Neutral Q93070 N265D Neutral Disease Q93070 D135E Neutral Neutral P01148 W16S Neutral Neutral O95786 R7C Neutral Neutral O95786 D580E Neutral Neutral Q9NY28 V611M Neutral Neutral Q9NY28 E267G Neutral Disease Q9NY28 Y53D Neutral Disease Q9NY28 Y53N Neutral Neutral Q9NY28 F312S Neutral Neutral Q9NY28 D438G Neutral Disease Q9NY28 E234K Neutral Neutral Q9NY28 V515F Neutral Neutral Q9NY28 A337V Neutral Neutral P16581 E295K Neutral Neutral P16581 A21S Neutral Disease P16581 H468Y Neutral Neutral P16581 L575F Neutral Neutral P16581 E421Q Neutral Neutral P16581 C130W Neutral Disease P16581 S149R Neutral Disease P16581 P550S Neutral Neutral P16581 Q257P Neutral Disease P16581 M31I Neutral Disease Q7Z4J2 H195R Neutral Disease Q7Z4J2 P219S Neutral Disease Q7Z4J2 A282E Neutral Neutral O95257 G112S Neutral Neutral Q8IYW2 S701G Neutral Neutral Q8IYW2 A492T Neutral Neutral Q86T75 L44V Neutral Neutral Q86T75 R41K Neutral Neutral Q9UIR0 M380I Neutral Neutral Q9UIR0 P393Q Neutral Neutral Q9UIR0 S334L Neutral Disease Q9UIR0 W94R Neutral Neutral Q9UIR0 A352T Neutral Disease Q9UIR0 K196E Neutral Neutral Q9UIR0 D283V Neutral Disease Q9UIR0 P379L Neutral Neutral Q9HCM7 L294P Neutral Disease Q9BSK2 L242I Neutral Neutral Q9NRF2 V541A Neutral Disease Q9NRF2 A484T Neutral Neutral P54098 R546C Neutral Neutral P54098 R627W Disease Disease P54098 Y831C Disease Neutral P54098 R309L Disease Disease P54098 R1047Q Disease Neutral P54098 L304R Disease Disease P54098 R953C Disease Disease P54098 W312R Disease Disease P54098 P324S Neutral Neutral P54098 R1146C Neutral Neutral P54098 R3P Disease Neutral P54098 A889T Disease Disease P54098 R1096C Disease Disease P54098 A1105T Disease Disease P54098 Q1236H Neutral Neutral P54098 R193Q Neutral Neutral P54098 S1104C Disease Disease P54098 R943H Disease Disease P54098 N468D Disease Neutral P54098 A467T Disease Neutral P54098 R1142W Neutral Disease P54098 R579W Disease Neutral P54098 R227W Disease Neutral P54098 E1143G Neutral Disease P54098 E662K Neutral Neutral P54098 G848S Disease Disease P54098 S1176L Disease Disease P54098 G923D Disease Disease P54098 G431V Disease Disease P54098 W748S Disease Neutral P54098 T251I Disease Neutral P54098 P587L Disease Neutral P54098 G1076V Disease Disease P54098 A957S Disease Disease P54098 Y955C Disease Disease P54098 V1106I Disease Disease P54098 N864S Disease Disease P54098 G1051R Disease Disease P54098 H932Y Disease Disease P54098 P18S Neutral Neutral Q9UBZ9 N1074K Neutral Neutral Q9UBZ9 P902S Neutral Neutral Q9UBZ9 V138M Neutral Neutral Q9UBZ9 F257S Neutral Neutral Q9UBZ9 M656V Neutral Neutral Q9UBZ9 L660W Neutral Disease Q9UBZ9 N373S Neutral Neutral Q9UBZ9 N1091T Neutral Neutral Q9UBZ9 P1060T Neutral Neutral Q9UBZ9 L1102P Neutral Neutral Q9UBZ9 A1003T Neutral Neutral Q9UBZ9 S921I Neutral Neutral Q9UBZ9 D700N Neutral Neutral Q9UBZ9 R704Q Neutral Neutral Q9UBZ9 N306D Neutral Neutral Q9UBZ9 P902H Neutral Neutral P51606 Q159R Neutral Neutral O76039 V793A Disease Neutral O76039 R175S Disease Neutral O76039 C152F Disease Disease O76039 P180L Disease Disease P08637 L66H Neutral Disease O75015 I106V Neutral Neutral O75015 S36R Neutral Neutral O75015 S65N Neutral Neutral O75015 N82D Neutral Neutral P08637 F157V Neutral Disease P08637 F176V Neutral Neutral P08637 L66R Neutral Neutral O75015 A78D Neutral Disease O15335 T350I Neutral Neutral Q8TCU8 R6H Neutral Neutral P20823 K158N Disease Disease P20823 K205Q Disease Neutral P20823 T620I Disease Neutral P20823 R131W Disease Disease P20823 C241G Disease Disease P20823 V133M Disease Disease P20823 V259D Disease Disease P20823 R159Q Disease Disease P20823 R159W Disease Disease P20823 Y122C Disease Disease P20823 G31D Disease Neutral P20823 T260M Disease Disease P20823 E48K Disease Neutral P20823 T537R Disease Neutral P20823 A161T Disease Disease P20823 P129T Disease Disease P20823 R229Q Disease Disease P20823 R583G Disease Neutral P20823 G415R Disease Neutral P20823 S432C Disease Neutral P20823 E619K Disease Neutral P20823 R271W Disease Disease P20823 S142F Disease Disease P20823 R272H Disease Disease P20823 I618M Disease Neutral P20823 P519L Disease Neutral P20823 R203H Disease Disease P20823 I128N Disease Disease P20823 R200W Disease Disease P20823 R203C Disease Disease P20823 S594I Disease Neutral P20823 H143Y Disease Disease P20823 L12H Disease Neutral P20823 R263C Disease Disease P20823 K117E Disease Neutral P20823 L107R Disease Disease P20823 P447L Disease Neutral P20823 G20R Disease Disease P20823 R131Q Disease Disease Q8N2C9 V98F Neutral Neutral Q8WWQ8 P510H Neutral Neutral P35368 V51G Neutral Disease Q9BVJ7 G131S Neutral Neutral Q93038 R23Q Neutral Neutral Q93038 R370L Neutral Disease Q93038 D159G Neutral Neutral Q93038 R381H Neutral Neutral Q93038 P254R Neutral Neutral Q14654 W91R Disease Disease Q14654 R301H Disease Disease Q14654 E23K Neutral Neutral Q14654 L164P Disease Disease Q14654 K67N Disease Disease Q14654 C166Y Disease Disease Q14654 R195H Neutral Disease Q14654 F55L Disease Disease Q14654 V59G Disease Disease Q14654 H46Y Disease Disease Q14654 E322K Disease Disease Q14654 R201C Disease Disease Q14654 G53D Disease Neutral Q14654 G53S Disease Neutral Q14654 R50P Disease Disease Q14654 R201H Disease Disease Q14654 A101D Disease Neutral Q14654 P266L Disease Disease Q14654 K170R Disease Disease Q14654 G40D Disease Disease Q14654 L147P Disease Disease Q14654 C42R Disease Disease Q14654 R201L Disease Disease Q14654 S385C Neutral Neutral Q14654 I296L Disease Disease Q14654 E10K Neutral Neutral Q14654 H259R Disease Disease Q14654 F35L Disease Neutral Q14654 S116P Disease Disease Q14654 R34H Disease Disease Q14654 V59M Disease Neutral Q14654 K170N Disease Disease Q14654 F333I Disease Disease Q14654 Y330S Disease Disease Q14654 L270V Neutral Neutral Q14654 I182V Disease Neutral Q14654 Q52R Disease Neutral Q14654 I148S Neutral Disease Q14654 R50Q Disease Neutral Q14654 K170T Disease Disease Q14654 G53R Disease Disease Q14654 R136L Disease Disease Q14654 I337V Neutral Neutral Q14654 P254L Disease Disease Q14654 Y330C Disease Disease Q14654 G134A Disease Neutral Q14654 F35V Disease Neutral Q14654 L355P Disease Disease Q9BX63 C832Y Neutral Disease Q9BX63 L195P Neutral Neutral Q9BX63 V935G Neutral Neutral Q9BX63 W647C Disease Disease Q9BX63 R419W Neutral Neutral Q9BX63 Q540L Neutral Neutral Q9BX63 V193I Neutral Neutral Q9BX63 R707C Disease Disease Q9BX63 R173C Neutral Disease Q9BX63 P1034L Disease Neutral Q9BX63 P919S Neutral Neutral Q9BX63 M299I Disease Neutral Q9BX63 P47A Disease Disease Q9BX63 A349P Disease Neutral Q9BX63 R264W Neutral Disease Q9BX63 Q255H Disease Disease Q9BX63 F531V Neutral Disease Q12888 E1014G Neutral Neutral Q12888 R1442Q Neutral Neutral Q12888 K1136Q Neutral Neutral Q12888 D841G Neutral Neutral Q12888 V1026A Neutral Neutral Q12888 E1137K Neutral Neutral Q12888 D353E Neutral Neutral Q12888 G1488W Neutral Disease Q12888 M648V Neutral Neutral Q12888 A1170G Neutral Neutral Q12888 Q699R Neutral Neutral Q12888 G412S Neutral Neutral Q12888 I1174V Neutral Neutral Q99835 R562Q Disease Neutral Q99835 D473H Neutral Disease Q99835 W535L Disease Disease Q9NRR2 M60V Neutral Neutral Q9NRR2 S132T Neutral Neutral Q9NRR2 I126M Neutral Neutral Q9NRR2 L288F Neutral Neutral Q9NRR2 W160S Neutral Disease Q9NRR2 L204I Neutral Neutral A1L453 M204V Neutral Neutral P10124 Q31R Neutral Neutral Q9Y2G1 A723T Neutral Neutral Q9BT76 Q293R Neutral Neutral Q9NVF9 R227Q Neutral Neutral Q9NY47 A138V Neutral Neutral P54289 D1045A Neutral Neutral P18283 R146C Neutral Disease P07203 P198L Neutral Neutral P07203 R5P Neutral Disease P18283 P126L Neutral Neutral P07203 A192T Neutral Neutral P18283 I176M Neutral Neutral O60925 M67R Neutral Disease Q9UQN3 I29V Neutral Neutral Q9UQN3 D148Y Disease Disease Q6UX15 E66K Neutral Disease O76074 S181A Neutral Neutral O76074 V93A Neutral Neutral Q9P2D1 F2750L Neutral Neutral Q9P2D1 L1815P Disease Disease Q9P2D1 W1031G Disease Disease Q9P2D1 R2319S Disease Disease Q9P2D1 Q1214R Disease Disease Q9P2D1 L1257R Disease Disease Q9P2D1 H2096R Disease Disease Q9P2D1 L1294P Disease Disease Q9P2D1 I1028V Disease Neutral Q9P2D6 D1242G Neutral Neutral Q9P2D6 I725V Neutral Neutral Q9P2D6 P954S Neutral Neutral P52597 K87R Neutral Neutral Q8N4B5 S136C Neutral Neutral Q15399 H118Y Neutral Neutral Q9BXR5 N241H Neutral Neutral Q15399 H305L Neutral Neutral Q9BXR5 I473T Neutral Neutral Q9BXR5 A163S Neutral Neutral Q15399 N248S Neutral Neutral Q9BXR5 Y736C Neutral Disease O60603 R579H Neutral Neutral Q15399 R80T Neutral Disease O60603 T411I Neutral Neutral Q15399 P315L Neutral Neutral Q9BXR5 R799Q Neutral Neutral Q15399 S602I Neutral Neutral Q9BXR5 I369L Neutral Neutral Q9BXR5 M326T Neutral Neutral Q9BXR5 R469G Neutral Disease Q9BXR5 R525W Neutral Neutral Q9BXR5 V298I Neutral Neutral O60603 R677W Neutral Disease O60603 R753Q Neutral Disease Q9BXR5 L167P Neutral Disease Q15399 V587G Neutral Disease Q9BXR5 G381D Neutral Disease O60603 P631H Neutral Neutral Q9BXR5 I775L Neutral Neutral P55000 G86R Disease Disease P55000 R71H Disease Neutral P55000 W15R Disease Neutral P55000 C77R Disease Disease P55000 C99Y Disease Disease Q96GJ1 S12R Neutral Neutral Q8TF21 A111T Neutral Neutral Q8TF21 S684A Neutral Neutral Q8TF21 E585K Neutral Neutral Q8TF21 R349Q Neutral Neutral Q9H3S3 D31V Disease Neutral Q9H3S3 R46Q Neutral Neutral Q9H3S3 V125M Neutral Neutral Q9H3S3 A317S Disease Neutral Q9H3S3 P337S Neutral Neutral Q9H3S3 F369L Neutral Neutral Q9H3S3 A249V Neutral Neutral Q8TET4 Q848R Neutral Neutral Q8TET4 R44Q Neutral Neutral Q14697 R154W Neutral Neutral Q8TET4 V11L Neutral Neutral Q8TET4 F845S Neutral Neutral Q8TET4 I153M Neutral Neutral Q14697 R173Q Neutral Neutral Q8TET4 D443E Neutral Neutral Q8N3Y7 R62W Neutral Disease Q9NP70 L354P Neutral Neutral Q86VL8 G429R Neutral Disease Q96PY5 Y352C Neutral Disease Q96PY5 M504T Neutral Neutral O43491 Q17H Neutral Neutral Q8IWF9 T49A Neutral Neutral Q96KN2 G6R Neutral Neutral Q96KN2 V113I Neutral Neutral P12034 M54V Neutral Neutral P35318 S50R Neutral Neutral Q15109 Q100R Neutral Neutral Q15109 G82S Neutral Neutral P25445 E272G Disease Neutral P25445 D260G Disease Neutral P25445 A25T Disease Neutral P25445 P183L Disease Neutral P25445 K299N Disease Neutral P25445 C178R Disease Neutral P25445 D260V Disease Disease P25445 A257D Disease Neutral P25445 T270I Disease Disease P25445 N255D Disease Neutral P25445 E272K Disease Disease P25445 T241K Disease Neutral P25445 I310S Disease Disease P25445 N118S Disease Neutral P25445 Y232C Disease Disease P25445 D260Y Disease Disease P25445 R121W Disease Neutral P25445 L180F Disease Neutral P25445 T305I Neutral Neutral P25445 L278F Disease Neutral P25445 N264K Disease Neutral P25445 T241P Disease Neutral P25445 T122I Neutral Neutral P25445 R250P Disease Disease P25445 T198I Disease Neutral P25445 A16T Neutral Neutral P25445 R250Q Disease Disease P25445 T28A Disease Neutral P25445 C82R Disease Disease Q658P3 A184T Neutral Neutral P51687 A265D Disease Disease P51687 R366H Disease Disease P51687 I258L Disease Neutral P51687 G362S Disease Disease P51687 R268Q Disease Disease P51687 S427Y Disease Disease P51687 W450R Disease Disease P51687 Q396R Disease Disease P51687 G530D Disease Disease P51687 R217Q Disease Disease P51687 K379R Disease Disease Q9NP95 D206N Neutral Neutral P31371 I94V Neutral Neutral Q9NP95 G116R Neutral Disease Q9NP95 P175A Neutral Neutral P00918 H94Y Disease Disease P00918 N252D Neutral Neutral P07451 V31I Neutral Neutral P00918 H107Y Disease Disease P00918 G144R Disease Disease P00918 Q92P Disease Disease Q9H2U1 C416S Neutral Neutral Q9H2U1 I583N Neutral Neutral Q9H2U1 E151K Neutral Neutral Q9UK00 V162A Neutral Neutral Q9UK00 A8D Neutral Neutral P43251 Q436H Disease Disease P43251 R518C Disease Disease P43251 A151T Disease Disease P43251 H303R Disease Neutral P43251 D424H Disease Disease P43251 D208Y Disease Disease P43251 G431D Disease Disease P43251 T512M Disease Disease P43251 F108V Disease Disease Q8N6G6 S242N Neutral Neutral Q92696 T420A Neutral Neutral Q8TF17 A468S Neutral Neutral Q8TF17 R529Q Disease Disease Q8TF17 R658C Disease Disease Q8TF17 E657K Disease Disease Q6NZY4 P672A Neutral Neutral Q01082 D1411H Neutral Disease O15020 L253P Disease Disease Q12802 V897M Neutral Neutral Q12802 G624V Neutral Neutral Q12802 W494R Neutral Neutral Q12802 M452T Neutral Neutral Q12802 P1062A Neutral Neutral Q12802 V845A Neutral Neutral Q12802 A2801T Neutral Neutral Q12802 R574C Neutral Neutral Q12802 D1086N Neutral Neutral Q12802 M1216T Neutral Neutral Q12802 E689K Neutral Neutral Q12802 G2457S Neutral Neutral Q11128 P187L Neutral Neutral P21217 L20R Neutral Disease P21217 R160C Neutral Disease P21217 D162N Neutral Disease P51993 Q230K Neutral Neutral P21217 T105M Neutral Disease P51993 P124S Neutral Disease P21217 R327Q Neutral Neutral P21217 T325M Neutral Neutral P21217 I356K Neutral Disease P21217 G5S Neutral Neutral P21217 G223R Neutral Disease P21217 G170S Neutral Disease P21217 V270M Neutral Disease Q86YF9 P736S Neutral Neutral P08567 W92R Neutral Disease P08567 K340R Neutral Neutral P08567 R5W Neutral Neutral P08567 K97N Neutral Neutral P48357 Q223R Neutral Neutral P48357 S675T Neutral Neutral P48357 K656N Neutral Neutral P48357 I503V Neutral Neutral P48357 K204R Neutral Neutral P48357 K109R Neutral Neutral O43186 R41Q Disease Disease O43186 V242M Disease Neutral O43186 E80A Disease Disease O43186 R90W Disease Disease P32243 P134A Disease Neutral O43186 G122D Disease Neutral P32243 P133T Disease Neutral O43186 R41W Disease Disease P32243 R89G Disease Disease Q9BUR4 R68G Neutral Neutral Q9BUR4 A522G Neutral Neutral Q9BUR4 P11S Neutral Neutral Q8IZL9 K281R Neutral Neutral Q8IZL9 S106N Neutral Disease Q8IZL9 A137T Neutral Neutral Q8IZL9 S86L Neutral Neutral Q06546 E345K Neutral Disease Q06546 A291V Neutral Neutral P41597 V64I Neutral Neutral P41597 G355E Neutral Neutral P41597 L45V Neutral Disease P20702 F971L Neutral Disease P20701 R144H Neutral Neutral P20702 W48R Neutral Disease P20702 A251T Neutral Neutral P20701 Q746K Neutral Neutral P20702 E547K Neutral Disease P20702 P517R Neutral Disease P20701 R791T Neutral Neutral P20701 R214W Neutral Disease O95876 G268S Neutral Neutral Q9H0U9 A74P Neutral Neutral Q9H489 P246H Neutral Disease Q9H0U9 P62S Neutral Neutral Q8N831 G109S Neutral Neutral Q8N831 R246C Neutral Disease Q8N831 A60V Neutral Neutral Q86VY4 I365V Neutral Neutral Q8N831 P116L Neutral Neutral Q86VY4 T120S Neutral Neutral Q9H633 Q77H Neutral Neutral Q9H493 A32V Neutral Neutral Q8WZ64 Q1523R Neutral Neutral O96013 R135Q Neutral Neutral O96013 A139T Neutral Neutral Q96PE7 R104L Neutral Disease Q9NS23 Y329C Neutral Neutral Q9NS23 K21Q Neutral Neutral Q9NS23 D133E Neutral Neutral Q9NS23 R53C Neutral Neutral Q9NS23 A137S Neutral Neutral P59093 P46T Neutral Disease P59093 T42M Neutral Neutral Q15080 R153H Neutral Neutral Q15080 L147I Neutral Neutral Q13393 P49A Neutral Neutral Q13393 V820M Neutral Disease Q13393 A622S Neutral Neutral Q6ZWL3 H331P Disease Disease P78329 V433M Neutral Neutral Q6ZWL3 G61S Disease Disease Q6ZWL3 S213N Neutral Neutral Q9HCS2 P13L Neutral Neutral Q08477 V270I Neutral Neutral Q9HCS2 D76N Neutral Neutral P98187 Y125F Neutral Neutral P13584 M331I Neutral Neutral Q6ZWL3 K259Q Neutral Neutral P78329 L519M Neutral Neutral Q6ZWL3 W44R Disease Disease Q9HCS2 V90I Neutral Neutral Q6NT55 H436D Disease Neutral Q6ZWL3 L22V Neutral Neutral P78329 A269D Neutral Neutral Q6ZWL3 M123V Disease Neutral Q6NT55 K505Q Neutral Neutral Q6ZWL3 R508H Disease Disease P78329 G185V Neutral Disease Q6NT55 F59L Disease Disease P13584 S322G Neutral Neutral Q6NT55 S178C Neutral Neutral Q6NT55 R243H Disease Disease P13584 R340C Neutral Disease P13584 V345I Neutral Neutral P13584 R375C Neutral Disease Q6NT55 R372W Disease Disease P78329 S7Y Neutral Neutral Q6ZWL3 S341P Disease Disease Q6ZWL3 I111T Disease Disease Q9HCS2 R188C Neutral Disease Q08477 A269D Neutral Neutral Q6ZWL3 E79D Disease Neutral Q02928 F434S Neutral Neutral P98187 P447Q Neutral Disease Q6NT55 H435Y Disease Disease P78329 W12G Neutral Neutral Q08477 I271T Neutral Disease P13584 R173W Neutral Disease P81172 R59G Disease Neutral P81172 C70R Disease Disease P81172 C78Y Disease Disease P81172 G71D Disease Disease Q9NZ09 N357K Neutral Neutral Q5JQF7 E41G Neutral Neutral Q16281 T153M Neutral Neutral Q16281 E198K Neutral Disease P29973 R28Q Neutral Neutral P29973 D114N Neutral Neutral Q16281 V529M Disease Disease Q16281 T291R Disease Neutral Q16281 R283W Disease Disease Q16281 P163L Disease Disease P29973 S316F Disease Disease Q16281 R410W Disease Neutral Q16281 R283Q Disease Disease Q16281 G557R Disease Disease Q16281 F547L Disease Disease