Protein Mutation Annotation PANTHER PhD-SNP SIFT SNAP Meta-SNP A0PJX2 G102R Polymorphism 0.316 0.682 0.52 48 0.727 A1X283 R43W Disease 0.774 0.892 0.00 71 0.926 A5D8T8 V118A Polymorphism 0.124 0.296 0.57 -10 0.173 A5LHX3 G49S Polymorphism 0.988 0.830 0.00 55 0.945 A6NCS4 F151L Disease 0.903 0.760 0.00 54 0.844 A6NJG2 T254A Polymorphism NA 0.109 0.69 18 0.054 A6NLE4 T36M Polymorphism NA 0.310 NA 42 0.109 A7E2F4 K480N Polymorphism 0.061 0.264 0.44 36 0.175 A8MXD5 E9K Polymorphism NA 0.633 NA 8 0.628 A8MXD5 G64S Disease NA 0.231 NA -27 0.126 A8MXD5 P38L Disease NA 0.322 NA -12 0.216 A8MXD5 F153V Disease NA 0.868 0.01 40 0.690 A8MXD5 R138C Disease NA 0.772 0.00 35 0.799 B3SHH9 F206L Polymorphism NA 0.179 0.52 -2 0.128 B7U540 K366R Disease 0.391 0.267 0.05 -10 0.269 B7U540 R205H Disease 0.981 0.822 0.05 15 0.857 B7U540 T140M Disease 0.956 0.906 0.05 55 0.937 B7U540 T354M Disease 0.953 0.646 0.05 17 0.842 C9JR72 K390N Disease 0.221 0.486 0.48 11 0.387 C9JR72 R248S Disease 0.730 0.822 0.01 63 0.911 C9JR72 R408C Disease 0.399 0.851 0.05 30 0.762 O00124 V18M Polymorphism 0.223 0.222 0.10 36 0.181 O00165 F141L Disease NA 0.599 0.00 15 0.650 O00165 L130R Disease NA 0.672 0.00 13 0.689 O00165 V172I Disease NA 0.062 0.38 -39 0.048 O00341 Q537R Polymorphism 0.053 0.233 1.00 -4 0.115 O00584 C184R Disease 0.987 0.956 0.08 75 0.953 O00744 R332W Disease 0.998 0.844 0.05 68 0.943 O14653 G144W Disease 0.986 0.891 0.00 69 0.965 O14795 E1232D Polymorphism 0.356 0.338 0.05 -13 0.269 O14867 S314P Polymorphism 0.306 0.500 0.05 30 0.460 O14904 A260T Polymorphism 0.381 0.218 0.05 16 0.353 O14939 G821S Polymorphism 0.082 0.401 0.76 -43 0.164 O15091 N437S Polymorphism 0.179 0.255 0.18 29 0.297 O15160 R279Q Disease 0.463 0.709 0.45 42 0.699 O15160 R279W Disease 0.886 0.828 0.05 55 0.915 O15198 K43E Disease 0.863 0.692 0.25 32 0.866 O15270 G382V Disease 0.695 0.937 0.00 60 0.931 O15270 I504F Disease 0.336 0.540 0.26 23 0.563 O15270 V359M Disease 0.697 0.451 0.01 29 0.673 O15382 T186R Polymorphism 0.295 0.342 0.54 -6 0.194 O43155 R486Q Polymorphism 0.124 0.477 0.30 49 0.544 O43159 P329S Polymorphism 0.144 0.104 0.42 -41 0.121 O43194 A50V Polymorphism 0.087 0.222 0.49 -13 0.139 O43364 Q186K Disease 0.386 0.870 0.06 64 0.686 O43462 M87I Disease 0.122 0.537 NA 39 0.308 O43462 F475S Disease 0.478 0.461 NA 24 0.324 O43462 H227L Disease 0.887 0.938 NA 20 0.896 O43462 N508S Disease 0.178 0.633 NA 31 0.416 O43462 R429H Disease 0.509 0.645 NA 44 0.719 O43462 W226L Disease 0.878 0.863 NA 35 0.810 O43570 E143K Disease 0.995 0.867 0.00 72 0.936 O43897 I629V Disease 0.194 0.394 0.16 25 0.279 O43897 M182L Disease 0.360 0.410 0.08 11 0.369 O43897 V238A Disease 0.451 0.569 0.22 37 0.516 O60486 E1499K Polymorphism 0.352 0.500 0.02 53 0.710 O60496 A152P Polymorphism 0.078 0.199 0.32 -30 0.039 O60716 R915K Polymorphism 0.091 0.248 0.80 9 0.171 O60883 G90D Polymorphism 0.070 0.188 1.00 4 0.117 O75531 A12T Disease 0.325 0.200 0.05 -14 0.340 O75626 G74S Polymorphism NA 0.179 0.00 -7 0.135 O75643 R681C Disease 0.979 0.890 0.00 71 0.946 O75643 R681H Disease 0.953 0.847 0.00 67 0.934 O75643 V683L Disease 0.343 0.765 0.29 44 0.674 O75643 Y689C Disease 0.869 0.706 0.03 58 0.920 O75643 R1090L Disease 0.939 0.932 0.00 58 0.949 O75643 S1087L Disease 0.645 0.863 0.02 27 0.862 O75674 R108S Polymorphism 0.351 0.460 0.03 15 0.454 O75678 A119T Polymorphism 0.158 0.106 0.61 19 0.096 O75746 Q590R Disease 0.330 0.392 0.28 46 0.571 O75908 E14G Polymorphism 0.295 0.353 0.23 10 0.244 O75908 T254I Polymorphism 0.402 0.265 0.44 -13 0.174 O75949 L172P Polymorphism NA 0.051 0.25 13 0.025 O76031 I488T Polymorphism 0.359 0.464 0.07 18 0.395 O94766 R277Q Disease 0.281 0.194 0.36 1 0.229 O94813 S1277F Polymorphism NA 0.489 0.05 31 0.535 O94850 E661G Polymorphism 0.197 0.043 NA -4 0.021 O94906 R729W Disease 0.838 0.738 0.02 46 0.877 O94913 Q651H Polymorphism 0.694 0.607 NA 23 0.689 O95155 V605I Polymorphism 0.162 0.059 0.29 -25 0.086 O95263 H305P Disease NA 0.874 0.03 28 0.788 O95298 L46V Polymorphism 0.097 0.303 0.19 -18 0.270 O95470 V21L Polymorphism NA 0.397 0.36 -48 0.191 O95625 T350N Polymorphism NA 0.307 0.01 -14 0.171 O95747 T304I Polymorphism 0.180 0.065 0.47 -42 0.076 O95859 A237P Disease 0.553 0.884 0.01 41 0.867 O95859 G188R Disease 0.626 0.143 0.19 20 0.200 O95859 L101H Disease NA 0.798 0.02 35 0.800 O95859 M210R Disease 0.456 0.459 0.01 51 0.672 O95977 R365L Polymorphism NA 0.518 0.67 41 0.434 O96009 I40T Polymorphism NA 0.044 1.00 -66 0.023 P00374 L80F Disease 0.472 0.340 0.35 -20 0.311 P00374 D153V Disease 0.529 0.858 0.04 14 0.842 P00540 S300P Polymorphism NA 0.109 1.00 -32 0.090 P00568 G40R Disease 0.987 0.773 0.00 71 0.928 P00568 G64R Disease 0.987 0.841 0.00 59 0.932 P00568 R128W Disease 0.992 0.820 0.00 67 0.942 P00568 Y164C Disease 0.920 0.875 0.00 63 0.902 P01213 L211S Disease 0.788 0.662 0.05 30 0.756 P01213 R138S Disease 0.083 0.078 0.05 -56 0.035 P01213 R212W Disease 0.980 0.885 0.05 58 0.966 P01213 R215C Disease 0.974 0.788 0.05 57 0.954 P01834 W40R Disease 0.883 0.940 0.00 68 0.948 P01854 W43C Polymorphism 0.860 0.943 0.00 69 0.949 P02042 A23E Polymorphism 0.255 0.347 1.00 -16 0.262 P02042 E44K Polymorphism 0.227 0.532 0.15 -6 0.344 P02042 G25D Polymorphism 0.922 0.970 0.00 71 0.946 P02042 V12G Polymorphism 0.858 0.909 0.00 39 0.888 P02753 G93D Disease 0.637 0.657 0.03 61 0.860 P02753 I59N Disease 0.855 0.773 0.00 52 0.917 P04808 K28M Polymorphism 0.119 0.042 0.05 -12 0.013 P07738 R62Q Disease 0.805 0.867 0.00 77 0.929 P07738 R90C Disease 0.961 0.920 0.00 59 0.940 P08174 A227P Polymorphism 0.173 0.332 0.40 -25 0.157 P08247 L2Q Polymorphism 0.150 0.449 0.01 13 0.282 P08247 D248N Polymorphism 0.131 0.187 0.54 12 0.147 P08247 G217R Disease 0.786 0.948 0.00 54 0.928 P08F94 A17V Disease NA 0.646 NA 5 0.559 P08F94 R92W Disease NA 0.617 0.03 46 0.731 P08F94 T36M Disease NA 0.768 0.00 44 0.785 P08F94 A293V Disease 0.170 0.670 0.01 51 0.655 P08F94 D703N Disease 0.435 0.903 NA 50 0.873 P08F94 F253L Disease 0.102 0.486 0.10 50 0.255 P08F94 F372L Disease 0.295 0.753 0.00 44 0.713 P08F94 G223S Disease 0.212 0.815 0.01 55 0.867 P08F94 G326V Disease 0.683 0.883 0.00 50 0.893 P08F94 G466E Disease 0.632 0.662 0.20 55 0.608 P08F94 G470V Disease 0.683 0.910 0.00 41 0.863 P08F94 H686P Disease 0.686 0.676 NA 41 0.758 P08F94 I222V Disease 0.067 0.273 0.01 28 0.198 P08F94 I246T Disease 0.226 0.559 0.01 41 0.443 P08F94 I307T Disease 0.479 0.827 0.00 57 0.889 P08F94 I473S Disease 0.564 0.819 0.12 31 0.818 P08F94 I539T Disease 0.479 0.479 0.00 23 0.631 P08F94 I757L Disease 0.200 0.177 NA 16 0.150 P08F94 M997K Disease 0.523 0.683 0.00 54 0.833 P08F94 P724R Disease 0.681 0.149 NA 62 0.188 P08F94 P739L Disease 0.661 0.352 NA 37 0.583 P08F94 P805L Disease 0.661 0.609 NA 42 0.736 P08F94 R496P Disease 0.679 0.698 0.01 43 0.840 P08F94 R760H Disease 0.406 0.146 NA 33 0.254 P08F94 T579M Polymorphism 0.669 0.470 NA 42 0.649 P08F94 T899P Disease 0.585 0.843 NA 53 0.875 P08F94 W656C Disease 0.844 0.797 NA 61 0.931 P08F94 Y255C Disease 0.544 0.636 0.00 63 0.815 P08F94 Y486H Disease 0.569 0.732 0.02 57 0.863 P08F94 A1030E Disease 0.538 0.760 0.05 51 0.851 P08F94 A1262V Polymorphism 0.068 0.111 0.16 32 0.080 P08F94 A2009T Disease 0.385 0.590 0.00 46 0.613 P08F94 A3207T Disease NA 0.436 0.01 46 0.529 P08F94 C1249W Disease 0.889 0.887 0.00 69 0.941 P08F94 C1472Y Disease 0.766 0.856 0.01 66 0.910 P08F94 C2422G Disease 0.542 0.830 0.84 55 0.674 P08F94 C2422R Disease 0.711 0.894 0.19 70 0.909 P08F94 C2688F Disease 0.719 0.690 NA 50 0.868 P08F94 C2803R Disease 0.711 0.667 0.03 63 0.702 P08F94 C3346R Disease NA 0.939 0.01 62 0.926 P08F94 C3622Y Disease NA 0.815 0.01 45 0.816 P08F94 D1942G Disease 0.504 0.546 0.02 28 0.738 P08F94 D2761Y Disease 0.770 0.827 0.05 47 0.859 P08F94 D2962G Disease NA 0.665 0.00 49 0.629 P08F94 D3293V Disease NA 0.643 0.02 48 0.631 P08F94 E1995G Disease 0.490 0.212 0.23 32 0.373 P08F94 E2431V Disease 0.611 0.506 0.01 51 0.842 P08F94 E3502V Disease NA 0.526 0.09 48 0.661 P08F94 E3529Q Disease NA 0.268 0.05 38 0.401 P08F94 G1122S Disease 0.511 0.768 0.01 61 0.722 P08F94 G1123S Disease 0.511 0.335 0.02 60 0.632 P08F94 G1971D Disease 0.638 0.842 0.00 64 0.911 P08F94 G2210E Disease 0.632 0.794 0.00 57 0.898 P08F94 G2224R Disease 0.711 0.772 0.00 63 0.904 P08F94 H3049R Disease NA 0.678 0.01 61 0.811 P08F94 H3124Y Disease NA 0.835 0.00 65 0.905 P08F94 I1998T Disease 0.479 0.622 0.00 54 0.719 P08F94 I2303F Disease 0.484 0.655 0.01 47 0.598 P08F94 I2331K Disease NA 0.898 0.00 60 0.898 P08F94 I2957T Disease NA 0.831 0.00 41 0.774 P08F94 I3081V Disease NA 0.592 0.00 24 0.583 P08F94 I3167L Disease NA 0.285 0.14 14 0.241 P08F94 I3177T Disease NA 0.549 0.01 40 0.732 P08F94 I3468V Disease NA 0.168 0.21 0 0.190 P08F94 I3553T Disease NA 0.612 0.02 29 0.720 P08F94 I3905N Polymorphism NA 0.115 NA 11 0.017 P08F94 L1407R Disease 0.673 0.795 0.00 62 0.898 P08F94 L2106R Disease NA 0.849 0.00 55 0.885 P08F94 L2134P Disease 0.760 0.876 0.00 36 0.835 P08F94 L2772P Disease NA 0.892 0.00 38 0.788 P08F94 M2804K Disease 0.444 0.717 0.00 58 0.859 P08F94 N3175D Disease NA 0.833 0.01 63 0.868 P08F94 N3175S Disease NA 0.740 0.01 51 0.626 P08F94 P1389T Disease 0.603 0.599 0.02 55 0.748 P08F94 P1486L Disease 0.661 0.738 0.00 48 0.858 P08F94 P3783S Disease NA 0.451 NA 29 0.536 P08F94 Q1917R Disease 0.367 0.318 0.03 49 0.275 P08F94 R1624W Disease 0.726 0.368 0.14 57 0.612 P08F94 R2573C Disease 0.823 0.880 0.00 60 0.938 P08F94 R3107P Polymorphism NA 0.659 0.23 34 0.593 P08F94 R3143I Polymorphism NA 0.126 0.38 45 0.254 P08F94 R3482C Disease NA 0.736 0.03 62 0.866 P08F94 R3957C Disease NA 0.780 NA 59 0.826 P08F94 S1584I Disease 0.599 0.903 0.01 53 0.881 P08F94 S1664F Disease 0.681 0.431 0.55 49 0.591 P08F94 S1833L Disease 0.533 0.587 0.21 53 0.757 P08F94 S1867N Disease 0.489 0.488 0.03 45 0.541 P08F94 S2219L Disease 0.533 0.438 0.13 3 0.579 P08F94 S2861G Disease NA 0.167 0.80 32 0.115 P08F94 S2983L Disease NA 0.206 0.06 36 0.349 P08F94 S3018F Disease NA 0.690 0.14 48 0.790 P08F94 S3505R Polymorphism NA 0.227 0.54 51 0.214 P08F94 T1781I Disease 0.478 0.656 0.03 55 0.701 P08F94 T2641A Disease 0.287 0.479 0.01 47 0.515 P08F94 V1741M Disease 0.522 0.500 0.00 46 0.587 P08F94 V1789L Disease 0.256 0.385 0.03 35 0.301 P08F94 V1817G Disease 0.554 0.612 0.04 49 0.687 P08F94 V1875G Disease 0.592 0.808 0.00 62 0.893 P08F94 V2032L Disease 0.256 0.702 0.00 38 0.486 P08F94 V2798G Disease 0.592 0.752 0.00 43 0.626 P08F94 V3036G Disease NA 0.670 0.00 36 0.751 P08F94 V3471G Disease NA 0.648 0.00 48 0.716 P08F94 W1928L Disease 0.518 0.840 0.01 63 0.906 P08F94 Y1136C Polymorphism 0.813 0.572 0.03 62 0.805 P08F94 Y1838C Disease 0.813 0.746 0.00 66 0.927 P08F94 Y2863C Disease NA 0.647 0.08 39 0.537 P0CG37 R112C Disease NA 0.877 0.00 44 0.814 P0CG37 R189C Polymorphism NA 0.281 NA 32 0.105 P0CW18 R176G Disease 0.687 0.464 0.01 48 0.704 P0CW18 W309S Disease 0.765 0.924 0.00 64 0.895 P0DI81 D47Y Disease 0.978 0.931 0.02 58 0.972 P0DI81 F83S Disease 0.716 0.913 0.00 42 0.866 P0DI81 S73L Disease 0.641 0.860 0.59 25 0.843 P0DI81 V130D Disease 0.645 0.820 0.00 57 0.902 P10074 S675A Polymorphism NA 0.258 0.50 45 0.395 P10914 M8L Disease 0.384 0.191 0.58 26 0.295 P10914 W11R Disease 0.996 0.886 0.00 69 0.956 P11487 L6P Disease 0.456 0.644 0.00 41 0.706 P11487 S156P Disease 0.527 0.844 0.05 34 0.869 P12104 A55T Polymorphism 0.694 0.035 0.05 -18 0.135 P12272 L44P Disease 0.774 0.664 0.00 48 0.781 P12272 L60P Disease 0.821 0.882 0.00 63 0.935 P12757 A38V Polymorphism NA 0.127 0.00 -32 0.015 P12814 T868S Polymorphism 0.084 0.100 0.05 -42 0.074 P13762 D105G Polymorphism 0.869 0.818 0.05 49 0.880 P14854 R20H Disease NA 0.687 0.00 55 0.778 P15421 G13E Polymorphism 0.046 0.122 0.05 -40 0.017 P15586 S94I Disease 0.578 0.754 0.00 53 0.864 P15586 G418E Disease 0.524 0.615 0.61 51 0.600 P15586 K340R Disease 0.803 0.792 0.00 56 0.857 P16401 A211T Polymorphism 0.240 0.057 0.24 -28 0.018 P16989 T75A Polymorphism 0.175 0.053 0.81 -49 0.067 P17038 S718P Polymorphism 0.474 0.786 0.05 22 0.625 P18031 P387L Polymorphism NA 0.181 0.21 23 0.169 P18464 E176V Polymorphism 0.244 0.096 0.05 -16 0.211 P18464 H195Y Polymorphism 0.709 0.141 0.05 3 0.256 P18464 S155R Polymorphism 0.255 0.120 0.05 -11 0.237 P19388 S44F Polymorphism 0.788 0.051 0.61 -10 0.054 P19419 S183N Polymorphism 0.256 0.059 0.53 -18 0.042 P19801 N659H Polymorphism 0.712 0.462 0.05 30 0.674 P20718 R84Q Polymorphism 0.198 0.250 0.05 13 0.239 P21583 N36S Disease 0.205 0.446 0.04 -5 0.403 P22102 V421I Polymorphism 0.402 0.051 1.00 -33 0.012 P22460 P228S Polymorphism 0.817 0.386 0.26 10 0.599 P23743 H538Y Polymorphism 0.320 0.938 0.05 19 0.726 P24046 M26V Polymorphism NA 0.125 0.05 27 0.011 P24071 D113N Polymorphism 0.072 0.878 0.17 2 0.177 P24588 T203I Polymorphism 0.272 0.027 0.81 -27 0.013 P26715 N29S Polymorphism 0.666 0.029 0.05 -13 0.141 P28331 D252G Disease 0.532 0.780 0.29 48 0.783 P28331 R241W Disease 0.967 0.787 0.00 69 0.931 P28907 R140W Polymorphism 0.924 0.364 0.05 36 0.611 P29074 T924S Polymorphism NA 0.018 1.00 -2 0.034 P29536 T295M Polymorphism 0.300 0.033 0.05 35 0.079 P30301 E134G Disease 0.993 0.815 0.05 50 0.925 P30301 T138R Disease 0.921 0.931 0.05 59 0.924 P30411 G354E Polymorphism 0.625 0.413 0.05 25 0.592 P31371 S99N Disease 0.570 0.712 0.05 35 0.817 P32239 L37F Polymorphism 0.310 0.099 0.09 29 0.151 P35219 S100P Disease 0.471 0.646 0.05 7 0.653 P35354 P428A Polymorphism 0.091 0.059 0.52 1 0.087 P35442 T133S Polymorphism 0.112 0.157 0.40 -38 0.080 P35658 G1592A Polymorphism 0.281 0.174 0.49 52 0.167 P35659 V140A Polymorphism 0.484 0.034 0.55 -8 0.041 P36382 A96S Disease 0.307 0.624 0.05 23 0.507 P36382 P88S Disease 0.966 0.934 0.05 50 0.951 P36382 V85I Disease 0.231 0.679 0.05 13 0.484 P36382 L221I Disease 0.833 0.705 0.05 23 0.803 P36382 L229M Disease 0.884 0.773 0.05 49 0.895 P40259 G137S Disease 0.639 0.701 0.00 49 0.657 P41214 T210I Polymorphism 0.297 0.159 0.07 -37 0.259 P41221 C83S Disease 0.945 0.858 0.05 43 0.898 P41221 C182R Disease 0.996 0.899 0.05 77 0.949 P41227 S37P Disease 0.718 0.939 0.10 15 0.862 P41970 P169L Polymorphism 0.154 0.095 0.05 10 0.118 P43243 S85C Disease 0.579 0.461 0.00 39 0.523 P43405 R45H Polymorphism 0.644 0.628 0.14 16 0.707 P45877 K86R Polymorphism 0.120 0.418 0.05 2 0.242 P45985 S16R Polymorphism NA 0.188 0.41 43 0.059 P46093 S295N Polymorphism 0.416 0.272 0.05 -9 0.199 P46976 T83M Disease 0.876 0.633 0.14 48 0.848 P47883 Y181H Polymorphism 0.709 0.614 0.05 68 0.816 P48146 Q206R Polymorphism 0.067 0.290 0.05 14 0.153 P48169 L26M Polymorphism NA 0.356 0.08 -25 0.413 P48544 R39H Polymorphism 0.686 0.669 0.05 30 0.747 P48544 G387R Disease 0.096 0.468 0.05 22 0.200 P48544 T158A Disease 0.835 0.826 0.05 46 0.845 P48645 E79G Polymorphism NA 0.294 0.15 -2 0.417 P48735 R140G Disease 0.898 0.912 0.00 61 0.946 P48735 R140Q Disease 0.865 0.943 0.00 62 0.949 P48960 R367Q Polymorphism NA 0.117 0.05 -33 0.162 P49459 G23R Disease 0.629 0.732 0.01 57 0.898 P49459 R11Q Disease 0.205 0.278 0.10 -20 0.205 P49588 R329H Disease 0.951 0.828 0.05 55 0.905 P49914 T202A Polymorphism NA 0.039 1.00 -11 0.052 P50549 S100G Polymorphism NA 0.061 0.05 -9 0.083 P51178 I574T Disease 0.473 0.653 0.05 31 0.780 P51178 T209R Disease 0.527 0.724 0.05 24 0.568 P51955 N354S Polymorphism 0.209 0.304 0.20 -8 0.211 P52292 P165R Polymorphism 0.745 0.897 0.05 67 0.889 P52895 H90Q Disease 0.430 0.574 0.05 58 0.662 P52895 I79V Disease 0.419 0.240 0.05 -4 0.301 P52895 H222Q Disease 0.374 0.086 0.05 -35 0.174 P52895 N300T Disease NA 0.717 0.05 20 0.776 P53597 G85A Disease 0.855 0.787 0.08 43 0.874 P53597 M14L Disease NA 0.259 0.48 13 0.067 P53597 P170R Disease 0.909 0.868 0.00 63 0.923 P53674 S129R Disease 0.348 0.624 0.00 39 0.711 P54821 F113S Disease 0.696 0.874 0.00 36 0.853 P55199 S297N Polymorphism 0.135 0.085 0.05 8 0.106 P55263 G30E Disease 0.856 0.897 0.14 59 0.848 P55263 A318E Disease 0.852 0.912 0.03 54 0.933 P55263 D235A Disease 0.508 0.911 0.02 36 0.861 P55316 F215L Disease 0.986 0.870 0.00 57 0.930 P55316 P109L Polymorphism NA 0.135 0.09 32 0.033 P55316 R244C Disease 0.998 0.913 0.00 48 0.895 P55773 V106M Polymorphism 0.229 0.107 0.44 -11 0.092 P55789 R194H Disease 0.770 0.708 0.05 45 0.862 P55957 S10G Polymorphism NA 0.062 0.75 -1 0.022 P56378 I9V Polymorphism 0.083 0.044 1.00 0 0.044 P56381 Y12C Disease 0.801 0.781 NA 69 0.909 P58872 V255M Polymorphism 0.578 0.268 0.24 19 0.431 P60369 C170Y Polymorphism 0.459 0.801 0.05 60 0.843 P62324 N139S Polymorphism 0.108 0.291 0.00 -27 0.211 P62826 R95I Polymorphism 0.563 0.704 0.03 21 0.806 P62854 D33N Disease 0.696 0.856 0.00 17 0.765 P62854 M115T Disease 0.149 0.112 0.00 15 0.180 P78316 Q716R Polymorphism 0.249 0.123 0.68 -7 0.123 P78383 R81H Polymorphism 0.241 0.473 0.16 -13 0.326 P78508 G77R Disease 0.640 0.874 0.05 13 0.830 P78508 R65P Disease 0.860 0.923 0.05 49 0.848 P78508 A167V Disease 0.511 0.696 0.05 6 0.503 P78508 C140R Disease 0.994 0.983 0.05 66 0.953 P78508 R297C Disease 0.928 0.879 0.05 72 0.940 P78508 T164I Disease 0.571 0.319 0.05 -68 0.468 P82980 E70Q Polymorphism 0.847 0.783 0.04 44 0.855 P84022 R287W Disease 0.987 0.968 0.05 63 0.954 P84022 T261I Disease 0.783 0.561 0.05 27 0.762 P98153 V473A Polymorphism 0.116 0.044 NA -11 0.026 P98173 W213C Polymorphism 0.555 0.779 0.05 61 0.874 Q00013 E448Q Polymorphism 0.278 0.098 0.05 -29 0.206 Q00796 N269T Polymorphism 0.794 0.068 1.00 -50 0.026 Q01344 V262A Polymorphism 0.204 0.141 0.39 22 0.209 Q01650 N230K Polymorphism 0.172 0.261 0.05 30 0.266 Q02224 E1925D Polymorphism NA 0.451 1.00 17 0.249 Q02224 S1581R Polymorphism NA 0.753 0.39 53 0.620 Q02246 P366L Polymorphism 0.128 0.511 0.05 0 0.296 Q02446 Q197K Polymorphism 0.082 0.789 0.12 56 0.811 Q02985 H71Y Polymorphism 0.369 0.583 0.05 8 0.490 Q03060 Q270R Polymorphism 0.205 0.537 0.12 35 0.630 Q03721 D318Y Polymorphism 0.998 0.957 0.00 65 0.953 Q05516 M617V Disease 0.733 0.215 0.02 19 0.110 Q05BV3 I269V Polymorphism NA 0.112 1.00 9 0.127 Q06210 D43V Disease 0.333 0.620 1.00 2 0.441 Q06210 T15A Disease 0.176 0.060 0.96 6 0.027 Q06210 T15M Disease 0.454 0.296 0.02 22 0.450 Q06210 D366Y Disease 0.588 0.729 0.04 27 0.786 Q06210 I121T Disease 0.694 0.572 0.00 44 0.811 Q06210 M509T Disease 0.195 0.401 0.64 -2 0.164 Q06210 M510T Disease 0.504 0.618 0.00 39 0.638 Q06210 R111C Disease 0.775 0.389 0.18 20 0.570 Q06210 R403H Disease 0.734 0.582 0.00 35 0.792 Q06210 R452H Disease 0.553 0.692 0.01 6 0.544 Q06210 R514W Disease 0.938 0.900 0.01 35 0.892 Q06210 R530W Disease 0.847 0.561 0.02 17 0.741 Q06210 V199F Disease 0.591 0.639 0.01 11 0.574 Q07011 A176D Polymorphism 0.356 0.225 0.60 19 0.375 Q07343 S703C Polymorphism 0.315 0.623 0.05 10 0.624 Q08648 R77Q Polymorphism NA 0.118 NA 7 0.031 Q11203 A13D Disease NA 0.889 0.02 32 0.795 Q11203 D370Y Disease 0.946 0.742 0.07 59 0.936 Q12756 T99M Disease 0.984 0.866 0.01 55 0.937 Q12756 A255V Disease 0.692 0.344 0.37 12 0.576 Q12796 P252L Polymorphism NA 0.109 0.07 13 0.107 Q12852 G640S Polymorphism 0.106 0.046 0.74 37 0.026 Q12879 N615K Disease 0.723 0.539 0.64 54 0.855 Q12918 I168T Polymorphism 0.703 0.442 0.01 14 0.516 Q12965 A159P Disease 0.939 0.848 0.00 43 0.885 Q12988 R7S Disease 0.189 0.689 0.00 34 0.423 Q13017 I17V Polymorphism NA 0.043 1.00 -36 0.009 Q13118 S249F Polymorphism 0.452 0.317 0.05 31 0.467 Q13158 C105W Disease 0.932 0.908 0.03 53 0.946 Q13224 R682C Disease 0.749 0.680 0.01 56 0.890 Q13243 A160S Polymorphism 0.652 0.911 0.08 36 0.833 Q13330 V372I Polymorphism 0.135 0.085 0.40 21 0.129 Q13362 A515P Polymorphism 0.344 0.638 0.00 -23 0.482 Q13509 R62Q Disease NA 0.816 0.05 57 0.895 Q13509 A302T Disease 0.347 0.805 0.05 -11 0.622 Q13509 A302V Disease 0.430 0.825 0.05 -7 0.521 Q13509 D417H Disease 0.601 0.695 0.05 9 0.796 Q13509 D417N Disease 0.352 0.647 0.05 -57 0.491 Q13509 E205K Disease 0.509 0.828 0.05 -10 0.671 Q13509 E410K Disease 0.336 0.854 0.05 24 0.677 Q13509 M323V Disease 0.124 0.710 0.05 -14 0.250 Q13509 R262C Disease 0.873 0.808 0.05 50 0.912 Q13509 R262H Disease 0.723 0.743 0.05 25 0.810 Q13509 R380C Disease 0.834 0.863 0.05 19 0.839 Q13509 T178M Disease 0.531 0.333 0.05 8 0.612 Q13591 S792L Polymorphism 0.281 0.290 0.05 -3 0.309 Q13772 L561P Polymorphism 0.381 0.666 NA 48 0.699 Q14108 H363N Disease 0.922 0.833 0.05 56 0.913 Q14449 F90I Polymorphism NA 0.167 0.05 20 0.103 Q14626 P221R Disease 0.998 0.547 0.00 47 0.859 Q14626 R296W Disease 0.783 0.646 0.00 54 0.859 Q14626 S245C Disease 0.657 0.678 0.05 29 0.741 Q14781 P98L Disease NA 0.058 0.09 17 0.098 Q14781 R443P Disease 0.160 0.469 0.26 6 0.207 Q14973 S267F Polymorphism 0.624 0.490 0.05 -14 0.589 Q15029 G773V Polymorphism 0.417 0.529 0.01 2 0.500 Q15058 P1633A Polymorphism NA 0.235 NA 22 0.135 Q15080 R105Q Disease 0.582 0.714 0.02 50 0.853 Q15797 V3A Disease NA 0.067 0.05 -13 0.101 Q16222 P418H Polymorphism 0.389 0.656 0.26 38 0.737 Q16531 L427F Polymorphism 0.450 0.645 0.03 29 0.603 Q16611 A28V Polymorphism 0.405 0.092 0.18 -2 0.114 Q16625 F219S Disease 0.384 0.477 0.12 14 0.571 Q16653 S133C Disease 0.634 0.673 0.11 31 0.764 Q17RN3 T240K Polymorphism NA 0.611 0.04 40 0.747 Q29974 S66N Polymorphism 0.223 0.234 0.05 -11 0.029 Q2M3V2 R124P Polymorphism NA 0.489 0.03 13 0.516 Q330K2 Q99R Disease NA 0.071 0.03 -28 0.126 Q3KP66 R538C Polymorphism NA 0.064 NA 30 0.031 Q3KPI0 T121N Polymorphism 0.362 0.877 0.05 29 0.739 Q3ZCM7 L345F Polymorphism 0.289 0.549 0.69 23 0.422 Q49MI3 E514G Polymorphism 0.231 0.202 0.03 22 0.281 Q49MI3 R106S Disease NA 0.603 0.02 51 0.607 Q4G163 P139R Polymorphism NA 0.248 0.00 28 0.193 Q4LDG9 N150S Disease 0.554 0.665 0.00 60 0.789 Q4VX76 P414S Polymorphism 0.485 0.701 0.40 18 0.510 Q53GG5 V127M Polymorphism 0.446 0.203 0.11 17 0.342 Q53RD9 V119M Polymorphism 0.099 0.234 0.23 15 0.289 Q569K6 D51N Polymorphism NA 0.690 0.00 32 0.472 Q587I9 R38G Polymorphism NA 0.059 0.16 6 0.019 Q5FWE3 Q138E Polymorphism 0.091 0.045 0.25 -16 0.019 Q5FWE3 R334G Polymorphism 0.115 0.039 0.27 -11 0.023 Q5FWF5 N191S Polymorphism NA 0.239 NA -30 0.138 Q5FYB0 S565R Polymorphism 0.054 0.075 0.02 31 0.047 Q5H9R4 R188G Polymorphism 0.072 0.067 0.20 23 0.033 Q5JSP0 V275I Polymorphism 0.056 0.068 0.71 -3 0.073 Q5JU85 Q791P Disease 0.616 0.897 0.05 45 0.870 Q5JU85 R349C Disease NA 0.879 0.00 70 0.910 Q5JU85 R748Q Disease NA 0.555 0.18 13 0.485 Q5JU85 R853W Disease 0.875 0.919 0.00 53 0.899 Q5JY77 I779V Polymorphism NA 0.060 0.39 -2 0.031 Q5QGT7 Q82R Polymorphism 0.105 0.396 0.05 12 0.322 Q5SQ13 L8F Polymorphism NA 0.200 NA 21 0.027 Q5SQ13 Q37R Polymorphism NA 0.020 NA 20 0.028 Q5SRE7 R222W Polymorphism 0.373 0.234 0.19 2 0.261 Q5SZD1 P235L Polymorphism NA 0.493 NA 33 0.235 Q5SZD1 Q137E Polymorphism NA 0.050 NA 10 0.023 Q5T0L3 A69V Polymorphism NA 0.034 1.00 -10 0.014 Q5T0L3 R217H Polymorphism NA 0.535 0.39 -24 0.409 Q5T292 P83L Polymorphism NA 0.090 NA -8 0.032 Q5T2S8 I343T Polymorphism 0.319 0.151 0.00 34 0.166 Q5T3U5 I948T Polymorphism NA 0.246 0.06 -28 0.251 Q5T4H9 R73P Polymorphism NA 0.632 NA 28 0.256 Q5T7M4 G14R Polymorphism NA 0.748 0.41 9 0.684 Q5T848 A425G Polymorphism NA 0.168 0.04 22 0.174 Q5TA78 G95V Polymorphism NA 0.335 NA 32 0.061 Q5TC84 S47P Polymorphism 0.601 0.039 0.30 16 0.028 Q5TEA3 F265L Polymorphism NA 0.225 NA 7 0.116 Q5TGJ6 T87M Polymorphism 0.803 0.216 0.11 -41 0.315 Q5VIR6 L375R Polymorphism 0.298 0.337 0.08 8 0.271 Q5VU57 V443M Polymorphism NA 0.206 0.10 -11 0.069 Q5VUB5 P465S Polymorphism NA 0.235 0.70 8 0.198 Q5VV41 H370Y Polymorphism 0.534 0.673 1.00 21 0.516 Q5VVW2 A752S Polymorphism 0.222 0.582 0.14 21 0.630 Q5VWJ9 D83H Polymorphism NA 0.583 0.22 6 0.513 Q5VYS4 R59G Polymorphism NA 0.062 NA 43 0.027 Q5Y7A7 D86S Polymorphism 0.369 0.431 0.05 5 0.357 Q5Y7A7 D86V Polymorphism 0.487 0.526 0.05 20 0.505 Q5Y7A7 N66F Polymorphism 0.337 0.105 0.05 -8 0.189 Q5Y7A7 N66S Polymorphism 0.223 0.197 0.05 1 0.252 Q5Y7A7 R54L Polymorphism 0.843 0.902 0.05 49 0.888 Q5Y7A7 T41K Polymorphism 0.565 0.063 0.05 -15 0.217 Q5Y7A7 E100K Polymorphism 0.276 0.120 0.05 -11 0.202 Q5Y7A7 V115G Polymorphism 0.232 0.145 0.05 25 0.204 Q658P3 A184T Polymorphism 0.190 0.152 0.05 -7 0.128 Q68J44 S137R Polymorphism 0.238 0.500 0.56 -2 0.270 Q693B1 G22S Polymorphism 0.440 0.630 0.08 64 0.573 Q69YQ0 Q415P Disease 0.864 0.756 0.01 45 0.876 Q69YQ0 V943A Polymorphism NA 0.144 0.21 0 0.099 Q6AI14 G116S Polymorphism NA 0.494 0.56 2 0.433 Q6AZZ1 Y466S Polymorphism 0.461 0.224 0.05 20 0.220 Q6IFH4 C179R Polymorphism 0.990 0.948 0.05 83 0.570 Q6KF10 G42V Disease 0.126 0.654 0.55 24 0.608 Q6KF10 A249E Disease 0.097 0.117 0.28 -34 0.134 Q6KF10 D216G Disease 0.453 0.528 0.05 37 0.768 Q6KF10 K424R Disease 0.381 0.167 0.13 -10 0.228 Q6KF10 L289P Disease NA 0.811 0.27 -41 0.538 Q6KF10 P327H Disease NA 0.054 0.45 -66 0.133 Q6KF10 Q119R Disease 0.131 0.175 0.57 -47 0.104 Q6KF10 Q253L Disease 0.072 0.059 0.33 -11 0.080 Q6NSI1 K265T Polymorphism 0.055 0.102 0.62 16 0.021 Q6NZ67 R155Q Polymorphism NA 0.067 0.38 54 0.047 Q6P1M0 A92T Disease 0.693 0.556 0.05 -39 0.717 Q6P1M0 Q300R Disease 0.562 0.555 0.05 30 0.593 Q6P1M0 R374C Disease 0.972 0.865 0.05 56 0.930 Q6P1M0 R583H Disease 0.923 0.743 0.05 49 0.903 Q6P1M0 S247P Disease 0.960 0.828 0.05 72 0.937 Q6P1Q0 V84I Polymorphism 0.050 0.242 0.58 -6 0.233 Q6P1S2 A47T Polymorphism NA 0.381 NA 28 0.250 Q6PII3 T436M Polymorphism 0.532 0.032 0.00 -4 0.100 Q6PJG2 A86V Polymorphism 0.292 0.272 NA 7 0.123 Q6UWJ8 M76V Polymorphism 0.141 0.035 0.78 12 0.024 Q6UXH8 C75S Disease 0.196 0.484 0.74 14 0.297 Q6UXH8 C102S Disease 0.286 0.835 0.00 57 0.885 Q6UXH8 C174R Disease 0.625 0.867 0.01 62 0.912 Q6UXH8 G327R Disease 0.502 0.420 0.00 64 0.788 Q6UXH8 R158C Disease 0.513 0.715 0.11 57 0.858 Q6UXZ4 R728K Polymorphism 0.208 0.125 0.73 -43 0.111 Q6VVX0 L99P Disease 0.648 0.869 0.05 59 0.907 Q6XYQ8 A505V Polymorphism NA 0.102 0.40 20 0.116 Q6XYQ8 T420S Polymorphism 0.394 0.043 1.00 -35 0.026 Q6ZN03 A149T Polymorphism NA 0.374 NA 19 0.074 Q6ZQR2 R184H Polymorphism NA 0.670 NA 47 0.734 Q6ZRP5 R2H Polymorphism NA 0.109 NA 8 0.053 Q6ZSC3 I259V Polymorphism NA 0.188 NA -5 0.075 Q6ZSY5 F351S Polymorphism 0.802 0.266 NA 26 0.320 Q6ZUF6 L73P Polymorphism NA 0.305 NA 24 0.060 Q6ZUL3 R81H Polymorphism NA 0.495 NA 31 0.238 Q6ZUT9 H487N Polymorphism NA 0.404 0.05 30 0.269 Q709F0 V362L Polymorphism NA 0.163 0.29 20 0.124 Q71SY5 A335V Disease 0.124 0.048 0.41 25 0.056 Q7L1T6 H223R Polymorphism 0.188 0.376 0.50 35 0.231 Q7L1T6 R140H Polymorphism 0.107 0.133 0.61 -28 0.058 Q7L4E1 G212S Polymorphism 0.120 0.076 0.95 -26 0.070 Q7RTV2 V55I Polymorphism 0.299 0.460 0.05 19 0.394 Q7Z2W7 M462T Polymorphism 0.944 0.866 0.01 28 0.891 Q7Z3G6 R148H Disease NA 0.805 0.02 60 0.767 Q7Z3G6 V153I Disease 0.142 0.167 0.19 -6 0.188 Q7Z3G6 V605F Disease NA 0.757 0.01 37 0.758 Q7Z3H0 Q132R Polymorphism NA 0.180 0.63 24 0.284 Q7Z3U7 A548T Polymorphism NA 0.203 0.46 13 0.258 Q7Z5B4 C130Y Polymorphism 0.220 0.576 1.00 32 0.384 Q7Z5M5 D1099N Polymorphism NA 0.037 1.00 -38 0.005 Q7Z699 V44D Disease 0.916 0.748 0.00 55 0.920 Q7Z699 W31C Disease 0.994 0.783 0.00 61 0.959 Q7Z6Z7 N483S Polymorphism NA 0.054 0.36 1 0.065 Q7Z7L9 S191T Polymorphism 0.056 0.142 0.05 -14 0.109 Q86SG6 A497P Disease NA 0.289 0.00 -36 0.227 Q86SG6 H425Y Disease 0.333 0.527 0.05 14 0.493 Q86SG6 L330F Disease 0.871 0.170 0.84 -20 0.125 Q86SS6 I238V Polymorphism 0.135 0.095 0.05 -23 0.145 Q86SU0 R97Q Disease NA 0.823 0.05 51 0.869 Q86SU0 R453Q Disease NA 0.104 0.05 41 0.042 Q86TM3 M381I Polymorphism 0.343 0.862 0.11 54 0.649 Q86UR1 P286L Polymorphism 0.262 0.076 0.41 17 0.096 Q86VF2 T1056M Polymorphism 0.676 0.179 0.03 38 0.523 Q86VH2 I213V Polymorphism 0.109 0.215 0.36 29 0.236 Q86WW8 A53P Disease NA 0.648 0.07 56 0.681 Q86X52 P539R Disease 0.939 0.926 0.05 58 0.949 Q86XE5 C257G Disease 0.661 0.305 0.29 22 0.560 Q86XE5 G287V Disease 0.479 0.798 0.05 11 0.553 Q86YI8 K20E Polymorphism 0.105 0.581 0.03 41 0.648 Q86YW0 S500L Polymorphism 0.446 0.480 0.03 23 0.469 Q8HWS3 R181Q Disease 0.263 0.873 0.00 68 0.905 Q8HWS3 S217P Disease 0.499 0.669 0.03 4 0.512 Q8IUC8 E59D Polymorphism 0.748 0.548 0.05 -6 0.768 Q8IV13 H234Y Polymorphism 0.308 0.453 1.00 47 0.299 Q8IVH8 V200L Polymorphism 0.271 0.175 1.00 -10 0.086 Q8IVI9 G473E Polymorphism NA 0.165 0.62 8 0.063 Q8IVL5 G508V Disease 0.885 0.679 0.05 35 0.836 Q8IVN8 F58L Polymorphism 0.146 0.074 0.55 -1 0.025 Q8IVU1 V751L Polymorphism NA 0.314 NA 29 0.179 Q8IW93 G163R Polymorphism NA 0.825 NA 43 0.776 Q8IWX8 N199H Polymorphism 0.199 0.372 0.00 26 0.275 Q8IWX9 D160E Polymorphism 0.054 0.032 0.05 9 0.031 Q8IX07 G70A Polymorphism 0.121 0.105 0.19 16 0.059 Q8IXK2 C479F Disease 0.996 0.965 0.05 77 0.950 Q8IXK2 D303N Disease 0.544 0.295 0.05 10 0.586 Q8IXK2 E341D Disease 0.979 0.745 0.05 53 0.915 Q8IXK2 G272R Polymorphism 0.374 0.766 0.05 36 0.604 Q8IXK2 R297W Disease 0.952 0.718 0.05 36 0.808 Q8IXK2 R373H Disease 0.672 0.271 0.05 -25 0.518 Q8IXK2 R382H Disease 0.981 0.857 0.05 50 0.940 Q8IXK2 T491M Disease 0.951 0.562 0.05 25 0.773 Q8IXL7 C89G Disease 0.723 0.899 0.00 69 0.887 Q8IXQ5 A153T Disease 0.253 0.703 0.05 39 0.530 Q8IXQ5 A153V Disease 0.327 0.705 0.05 49 0.829 Q8IXQ5 S150N Disease 0.365 0.153 0.05 -5 0.167 Q8IXX5 R10M Polymorphism 0.162 0.300 NA 53 0.349 Q8IY81 Q91E Polymorphism 0.380 0.218 0.77 -15 0.032 Q8IY81 S424C Polymorphism 0.350 0.543 0.00 4 0.545 Q8J025 L9R Disease NA 0.641 0.02 15 0.604 Q8N1C3 G403E Polymorphism 0.217 0.492 0.05 0 0.387 Q8N1N2 T189P Polymorphism NA 0.168 NA 17 0.053 Q8N2H9 V287M Polymorphism 0.332 0.173 0.09 29 0.259 Q8N2N9 S534A Polymorphism 0.047 0.017 0.66 -29 0.018 Q8N309 Q256K Polymorphism NA 0.756 0.04 30 0.752 Q8N326 R70K Polymorphism NA 0.357 NA 26 0.065 Q8N3Y1 T536M Polymorphism NA 0.193 0.03 31 0.343 Q8N3Y1 V563M Polymorphism NA 0.256 0.08 -14 0.201 Q8N3Z0 R224Q Polymorphism NA 0.075 0.44 40 0.070 Q8N468 G314A Polymorphism 0.081 0.129 1.00 37 0.105 Q8N4T0 F45L Polymorphism 0.083 0.328 0.13 -67 0.140 Q8N565 G15R Polymorphism NA 0.103 0.00 65 0.069 Q8N5B7 C75R Polymorphism 0.476 0.500 0.05 11 0.402 Q8N5N7 L127F Polymorphism NA 0.664 0.00 31 0.708 Q8N697 V239A Polymorphism 0.415 0.298 0.05 -1 0.306 Q8N6T3 V184M Polymorphism 0.359 0.344 0.05 27 0.481 Q8N8E2 C339R Disease NA 0.880 0.01 18 0.724 Q8N8I6 V50L Polymorphism NA 0.471 NA 15 0.181 Q8N910 I160T Polymorphism NA 0.032 NA 21 0.027 Q8N961 T732A Polymorphism 0.150 0.064 0.78 -23 0.064 Q8N9U0 S172N Polymorphism 0.346 0.149 0.45 27 0.088 Q8NA23 P113S Polymorphism 0.175 0.763 0.33 24 0.341 Q8NAC3 S182L Polymorphism NA 0.172 NA 10 0.167 Q8NB50 R698K Polymorphism NA 0.091 0.05 -32 0.179 Q8NB59 G138E Polymorphism 0.503 0.222 0.36 10 0.317 Q8NB59 G439D Disease 0.613 0.855 0.01 68 0.913 Q8NBI5 P53L Polymorphism NA 0.104 0.42 -15 0.134 Q8NBP5 I288T Polymorphism 0.610 0.304 0.23 26 0.481 Q8NCH0 C289S Disease 0.988 0.962 0.05 55 0.961 Q8NCH0 L137Q Disease 0.636 0.563 0.05 -18 0.523 Q8NCH0 P281L Disease 0.619 0.471 0.05 41 0.684 Q8NCH0 R135G Disease 0.389 0.566 0.05 32 0.719 Q8NCH0 R213P Disease 0.991 0.937 0.05 70 0.960 Q8NCH0 Y293C Disease 0.992 0.932 0.05 67 0.960 Q8NET5 H137Y Polymorphism NA 0.564 NA 23 0.698 Q8NET8 R117G Polymorphism NA 0.467 0.05 38 0.587 Q8NEZ2 I206F Polymorphism 0.392 0.452 NA 12 0.296 Q8NFU5 M349I Polymorphism 0.132 0.133 0.00 28 0.067 Q8NFW5 A205P Polymorphism NA 0.220 0.29 16 0.052 Q8NGE1 I37V Polymorphism 0.060 0.071 0.05 -49 0.116 Q8NGF1 S245A Polymorphism 0.310 0.167 0.05 -20 0.176 Q8NGQ1 N206D Polymorphism 0.121 0.053 0.05 6 0.219 Q8NGX6 A191T Polymorphism 0.325 0.242 0.05 -10 0.195 Q8NGX8 T104I Polymorphism 0.380 0.603 0.05 6 0.255 Q8NH16 F249L Polymorphism 0.135 0.104 0.05 -28 0.175 Q8NH53 A101T Polymorphism 0.145 0.140 0.05 -6 0.161 Q8NH53 C125Y Polymorphism 0.453 0.234 0.05 -3 0.028 Q8TAG5 E84K Polymorphism NA 0.122 0.66 20 0.119 Q8TAQ9 L177V Polymorphism 0.335 0.460 0.17 9 0.442 Q8TBH0 A244T Polymorphism 0.216 0.098 0.05 -2 0.220 Q8TBH0 L396P Polymorphism 0.096 0.173 0.05 -28 0.039 Q8TBH0 R192H Polymorphism 0.413 0.630 0.05 32 0.602 Q8TBP0 E476K Polymorphism 0.149 0.370 0.06 54 0.292 Q8TC36 A174T Polymorphism 0.275 0.242 0.43 -5 0.305 Q8TCJ0 N36D Polymorphism 0.072 0.145 0.87 10 0.084 Q8TCT8 V90I Polymorphism NA 0.563 0.05 -14 0.492 Q8TD33 I70R Polymorphism NA 0.551 0.10 50 0.681 Q8TD43 E7K Disease NA 0.213 0.79 16 0.209 Q8TD43 A432T Disease 0.926 0.839 0.00 22 0.864 Q8TD43 D561A Polymorphism 0.581 0.649 0.30 -31 0.511 Q8TD43 G582S Disease 0.610 0.694 0.30 -59 0.471 Q8TD43 G844D Disease NA 0.556 0.00 30 0.726 Q8TD43 K914R Disease 0.537 0.491 0.31 -4 0.491 Q8TD43 P970S Disease 0.626 0.835 0.19 49 0.664 Q8TD43 Q131H Disease 0.519 0.407 0.20 39 0.587 Q8TD43 Q293R Disease 0.385 0.159 0.41 -62 0.161 Q8TD43 R164W Disease 0.978 0.926 0.00 27 0.936 Q8TD43 Y790H Disease 0.934 0.896 0.00 44 0.896 Q8TD43 P1204L Polymorphism NA 0.140 0.50 -60 0.088 Q8TDB4 A128T Polymorphism 0.445 0.108 NA -1 0.057 Q8TDJ6 S1288P Polymorphism 0.315 0.218 0.02 -12 0.223 Q8TDW5 I275V Polymorphism NA 0.168 0.29 25 0.155 Q8TEU8 R31Q Polymorphism NA 0.165 0.01 0 0.018 Q8TF64 G46R Disease 0.911 0.834 0.05 66 0.938 Q8TF64 G94D Disease 0.888 0.746 0.05 55 0.925 Q8TF64 M88I Disease 0.609 0.616 0.05 43 0.647 Q8TF64 G256D Disease 0.888 0.792 0.05 54 0.928 Q8TF64 L262R Disease 0.894 0.788 0.05 67 0.935 Q8TF64 R189C Disease 0.887 0.415 0.05 36 0.628 Q8TF64 T221I Disease 0.814 0.602 0.05 32 0.820 Q8TF65 L206P Polymorphism 0.280 0.073 0.32 -41 0.053 Q8WU79 A289T Polymorphism 0.286 0.177 0.05 -18 0.094 Q8WVQ1 P299L Disease 0.777 0.786 0.00 41 0.858 Q8WVQ1 R300C Disease 0.884 0.800 0.00 68 0.936 Q8WVQ1 R300H Disease 0.743 0.776 0.00 69 0.917 Q8WVV5 P479S Polymorphism 0.439 0.307 0.05 32 0.399 Q8WVZ1 G66A Polymorphism 0.692 0.184 0.71 -37 0.315 Q8WW43 F217L Polymorphism 0.108 0.692 0.05 -15 0.473 Q8WWI1 P1547Q Polymorphism 0.789 0.500 0.00 34 0.722 Q8WXE1 K125Q Polymorphism NA 0.426 0.12 17 0.504 Q92526 R17Q Polymorphism 0.162 0.631 0.05 -8 0.327 Q92610 G1046R Disease 0.080 0.248 0.77 19 0.154 Q92743 A252T Disease 0.965 0.838 0.00 45 0.908 Q92743 V297M Disease 0.670 0.674 0.00 58 0.869 Q92835 H1169Y Polymorphism NA 0.663 0.05 28 0.433 Q92901 P291L Polymorphism 0.199 0.112 0.49 -21 0.123 Q92979 D86G Disease 0.793 0.726 0.00 58 0.916 Q95IE3 A13T Polymorphism 0.318 0.391 0.05 -54 0.298 Q95IE3 S89Y Polymorphism 0.479 0.114 0.05 -29 0.236 Q95IE3 R262T Polymorphism NA 0.022 0.05 -18 0.108 Q969R2 M760V Polymorphism 0.111 0.044 0.32 13 0.109 Q96CB8 T323A Polymorphism 0.068 0.024 0.47 -18 0.041 Q96CK0 K54R Polymorphism NA 0.398 NA 24 0.330 Q96DD0 I121L Polymorphism 0.120 0.180 0.05 -36 0.192 Q96DV4 D371H Polymorphism NA 0.806 0.00 58 0.886 Q96EL3 A4S Polymorphism NA 0.024 NA -54 0.023 Q96EU6 A78G Polymorphism 0.140 0.069 0.50 -47 0.055 Q96EY7 S681G Polymorphism 0.575 0.045 NA 38 0.072 Q96F45 N509K Polymorphism 0.320 0.818 0.22 10 0.639 Q96FF9 S156Y Polymorphism NA 0.240 0.05 37 0.401 Q96GW7 S356L Polymorphism 0.319 0.384 0.29 -1 0.397 Q96JA4 N177Y Polymorphism NA 0.348 0.07 41 0.342 Q96JF0 G154R Polymorphism NA 0.251 0.23 16 0.115 Q96JQ0 L2172Q Polymorphism NA 0.493 0.47 -46 0.234 Q96JQ0 R2359C Polymorphism NA 0.765 0.04 43 0.815 Q96JQ5 K52E Polymorphism 0.161 0.558 1.00 13 0.348 Q96K62 D293E Polymorphism NA 0.108 0.68 -21 0.074 Q96KJ9 E138K Disease 0.684 0.464 0.01 52 0.675 Q96KM6 A453T Polymorphism NA 0.170 0.13 29 0.171 Q96KS9 T107S Polymorphism NA 0.032 0.77 -16 0.045 Q96L92 E459K Polymorphism 0.291 0.320 0.56 40 0.495 Q96LC7 R520S Polymorphism 0.110 0.184 0.39 11 0.158 Q96LL4 L285M Polymorphism NA 0.017 NA 15 0.034 Q96M86 V240E Polymorphism NA 0.107 NA 23 0.013 Q96M86 R1358C Polymorphism NA 0.870 0.00 63 0.915 Q96M89 D99Y Polymorphism NA 0.390 0.00 32 0.259 Q96MU5 R47S Polymorphism NA 0.469 NA 39 0.148 Q96MU7 H183R Polymorphism NA 0.028 0.54 -22 0.027 Q96ND0 E167K Polymorphism 0.487 0.804 0.21 25 0.755 Q96NJ3 N208S Polymorphism 0.386 0.255 0.05 27 0.416 Q96NJ5 R5C Polymorphism NA 0.356 0.05 47 0.574 Q96NR3 L73F Polymorphism 0.197 0.258 0.24 28 0.243 Q96NW4 S657G Polymorphism NA 0.084 0.14 17 0.205 Q96NY7 D632G Polymorphism 0.525 0.834 0.16 49 0.874 Q96QU6 D59N Polymorphism NA 0.195 0.49 -20 0.179 Q96SN7 A15P Polymorphism NA 0.311 0.05 -23 0.150 Q96T17 N182S Polymorphism 0.223 0.036 0.88 -32 0.046 Q96T54 S21G Polymorphism 0.325 0.300 0.35 -4 0.231 Q96T54 R296Q Polymorphism 0.203 0.132 0.42 38 0.112 Q99523 D358Y Polymorphism 0.511 0.559 0.01 22 0.519 Q99583 A109T Polymorphism NA 0.061 0.45 -40 0.015 Q9BQB4 V21L Disease 0.152 0.268 0.00 11 0.149 Q9BQB4 V21M Disease 0.361 0.375 0.00 22 0.243 Q9BQB4 C167R Disease 0.873 0.872 0.00 67 0.945 Q9BQI6 S288R Polymorphism 0.203 0.181 NA 0 0.027 Q9BR09 E211K Polymorphism 0.528 0.720 0.07 20 0.514 Q9BR39 A396T Polymorphism 0.555 0.333 0.21 -17 0.477 Q9BR39 S101R Disease 0.211 0.371 0.52 26 0.356 Q9BR39 S165F Disease 0.953 0.400 0.03 20 0.651 Q9BR39 Y141H Disease 0.900 0.608 0.28 22 0.833 Q9BRP7 I87N Polymorphism NA 0.355 NA 26 0.045 Q9BRP7 T28A Polymorphism 0.128 0.088 NA 23 0.115 Q9BRP7 T475P Polymorphism 0.363 0.513 0.00 36 0.446 Q9BSH5 G146E Polymorphism 0.356 0.185 0.96 -18 0.046 Q9BSJ8 R764C Polymorphism 0.597 0.590 0.02 45 0.781 Q9BTN0 A14V Polymorphism NA 0.094 0.05 -79 0.168 Q9BTZ2 A31T Polymorphism 0.148 0.133 0.05 -50 0.147 Q9BUA3 E58Q Polymorphism NA 0.184 0.00 9 0.258 Q9BVA1 F265L Disease 0.385 0.727 0.05 46 0.791 Q9BVA1 I210T Disease 0.527 0.876 0.05 32 0.862 Q9BVA1 L228P Disease 0.815 0.808 0.05 44 0.868 Q9BVA1 S172P Disease 0.584 0.688 0.05 14 0.707 Q9BVA1 T312M Disease 0.699 0.692 0.05 29 0.820 Q9BWP8 G204S Disease 0.713 0.715 0.91 47 0.722 Q9BWP8 S169P Disease 0.458 0.542 0.20 40 0.456 Q9BXT5 K1439R Polymorphism 0.056 0.058 NA 29 0.055 Q9BXU7 L364F Polymorphism 0.286 0.041 0.05 -48 0.107 Q9BY21 T205M Polymorphism 0.055 0.115 0.05 -10 0.154 Q9BYC5 T267K Polymorphism 0.446 0.350 0.18 -12 0.252 Q9BYE0 I58V Disease 0.278 0.462 0.21 -4 0.302 Q9BYE0 R25W Disease 0.999 0.784 0.00 54 0.956 Q9BYE0 D186Y Disease 0.385 0.185 0.04 42 0.219 Q9BYR0 D18V Polymorphism 0.459 0.276 0.05 38 0.410 Q9BZJ6 V21M Polymorphism NA 0.450 NA 45 0.283 Q9BZM3 G107S Polymorphism NA 0.094 1.00 -1 0.082 Q9BZQ6 I820S Polymorphism NA 0.197 NA -3 0.133 Q9C030 E154K Polymorphism 0.316 0.161 0.05 16 0.217 Q9C0B1 R316Q Disease NA 0.742 0.00 63 0.879 Q9GIY3 A86D Polymorphism 0.411 0.108 0.05 -16 0.172 Q9GIY3 F66Y Polymorphism 0.296 0.144 0.05 -15 0.206 Q9GIY3 H89S Polymorphism 0.374 0.319 0.05 18 0.209 Q9GIY3 L56M Polymorphism 0.767 0.537 0.05 2 0.728 Q9GIY3 R54Q Polymorphism 0.669 0.757 0.05 32 0.766 Q9GIY3 S40R Polymorphism 0.379 0.374 0.05 25 0.320 Q9GIY3 S40V Polymorphism 0.219 0.168 0.05 -11 0.185 Q9GIY3 A102S Polymorphism 0.707 0.668 0.05 2 0.766 Q9GIY3 E103A Polymorphism 0.209 0.079 0.05 6 0.156 Q9GIY3 H110Y Polymorphism 0.628 0.750 0.05 38 0.604 Q9GIY3 T106N Polymorphism 0.602 0.517 0.05 6 0.534 Q9GIY3 Y141H Polymorphism 0.804 0.033 0.05 -23 0.165 Q9GZK6 L14I Polymorphism 0.315 0.047 0.05 -52 0.232 Q9GZQ6 I145L Polymorphism 0.298 0.685 0.05 60 0.760 Q9GZS1 D254H Polymorphism NA 0.500 0.10 33 0.717 Q9H1Z8 A52T Polymorphism NA 0.311 0.05 13 0.402 Q9H1Z9 R187H Polymorphism 0.095 0.339 0.07 -30 0.185 Q9H223 V154I Polymorphism 0.154 0.041 0.05 -28 0.113 Q9H228 L318Q Polymorphism 0.603 0.621 0.06 -40 0.518 Q9H2U1 E151K Polymorphism NA 0.585 0.22 36 0.484 Q9H329 N816T Polymorphism 0.306 0.340 NA -8 0.141 Q9H334 S5P Polymorphism NA 0.318 0.05 35 0.483 Q9H336 A286S Polymorphism NA 0.154 0.42 20 0.082 Q9H3Z4 L115R Disease 0.765 0.664 0.36 39 0.709 Q9H4B0 A229P Polymorphism 0.950 0.882 0.00 61 0.818 Q9H4G0 P854S Disease 0.760 0.817 0.05 31 0.846 Q9H4I2 N310S Polymorphism NA 0.297 0.01 12 0.267 Q9H553 S11P Polymorphism NA 0.409 0.22 -6 0.218 Q9H5Y7 P315R Polymorphism NA 0.438 0.05 7 0.341 Q9H6I2 G178C Disease 0.484 0.758 0.11 28 0.759 Q9H6I2 Y259N Disease 0.116 0.584 0.24 25 0.289 Q9H6U6 I106V Polymorphism 0.202 0.056 NA -6 0.092 Q9H6Y7 N121K Polymorphism 0.183 0.271 0.02 3 0.251 Q9H7B7 K32E Polymorphism NA 0.776 NA 28 0.482 Q9H845 R477Q Polymorphism NA 0.316 0.05 -47 0.265 Q9H8H3 A134T Polymorphism 0.074 0.405 0.59 5 0.235 Q9H8M5 T568I Disease 0.821 0.859 0.05 57 0.924 Q9H9L3 N130S Polymorphism NA 0.142 0.71 10 0.088 Q9H9L4 P445T Polymorphism 0.110 0.476 0.04 14 0.425 Q9HA77 Q555P Polymorphism 0.326 0.259 0.24 4 0.176 Q9HAQ2 V78I Polymorphism 0.173 0.263 0.66 -2 0.222 Q9HB19 I186N Polymorphism 0.456 0.492 0.28 22 0.666 Q9HBE1 E685D Polymorphism NA 0.150 0.58 25 0.121 Q9HBF5 P57L Polymorphism NA 0.817 NA 25 0.504 Q9HBG6 W7C Disease NA 0.828 NA 73 0.904 Q9HBG6 S322F Disease 0.468 0.576 0.01 42 0.650 Q9HBG6 V502G Disease 0.711 0.786 0.02 37 0.841 Q9HCH3 R582H Polymorphism NA 0.153 0.55 16 0.126 Q9HCK0 H236R Polymorphism NA 0.169 0.67 33 0.145 Q9HCU0 H457R Polymorphism 0.080 0.055 0.02 -44 0.018 Q9HD36 L11R Polymorphism 0.372 0.072 NA -32 0.020 Q9HD40 A239T Disease 0.309 0.605 0.07 13 0.486 Q9HD40 Y334C Disease 0.777 0.423 0.00 39 0.637 Q9NPC2 G236R Disease 0.863 0.902 0.11 31 0.875 Q9NPC6 S48P Disease 0.905 0.709 0.00 39 0.866 Q9NPC6 I246M Disease 0.392 0.127 0.02 18 0.102 Q9NPE2 D267G Polymorphism NA 0.053 1.00 -33 0.010 Q9NPI8 V295I Polymorphism NA 0.288 NA -8 0.135 Q9NQ87 H47R Polymorphism 0.157 0.047 0.05 -11 0.091 Q9NQT8 V1471I Polymorphism NA 0.166 0.00 1 0.234 Q9NQX1 Y107C Disease NA 0.699 0.05 35 0.628 Q9NR28 S126L Disease NA 0.500 0.00 -4 0.495 Q9NRR6 K580E Disease 0.224 0.575 0.29 60 0.765 Q9NRR6 R378C Disease 0.865 0.906 0.00 46 0.898 Q9NRR6 R435Q Disease 0.995 0.811 0.01 61 0.968 Q9NRR6 R512W Disease 0.777 0.656 0.19 27 0.766 Q9NRR6 R515W Disease 0.635 0.693 0.01 37 0.779 Q9NRR6 R563H Disease 0.370 0.418 0.17 26 0.435 Q9NSK7 G53R Disease NA 0.822 0.00 0 0.746 Q9NSK7 G65E Disease NA 0.806 0.00 71 0.902 Q9NSK7 G69R Disease NA 0.769 0.00 63 0.883 Q9NSK7 T11M Disease NA 0.251 NA 37 0.156 Q9NSK7 K142E Disease NA 0.630 0.00 -6 0.492 Q9NSV4 N363S Polymorphism 0.323 0.308 0.62 25 0.358 Q9NTZ6 N572S Polymorphism 0.184 0.405 0.36 -6 0.330 Q9NTZ6 P921L Polymorphism 0.928 0.816 0.01 10 0.877 Q9NUD9 A341E Disease 0.501 0.818 0.27 23 0.792 Q9NUD9 A341V Disease 0.392 0.607 0.21 1 0.514 Q9NUD9 H385P Disease 0.827 0.870 0.26 47 0.786 Q9NUD9 Q256K Disease 0.284 0.865 0.48 37 0.576 Q9NV39 Q137R Polymorphism NA 0.119 NA 17 0.047 Q9NV64 A487T Polymorphism 0.085 0.057 0.27 1 0.042 Q9NW07 N32S Polymorphism NA 0.061 0.75 0 0.078 Q9NWM0 H522Y Polymorphism 0.844 0.761 1.00 38 0.851 Q9NWU5 G154S Polymorphism 0.272 0.480 0.02 3 0.480 Q9NX24 V126M Disease 0.410 0.344 0.08 -47 0.319 Q9NX24 Y139H Disease 0.231 0.463 0.03 12 0.388 Q9NX62 D177N Disease 0.944 0.832 0.00 67 0.947 Q9NX62 T183P Disease 0.623 0.759 0.05 65 0.902 Q9NXL6 G3S Polymorphism NA 0.153 0.05 -8 0.058 Q9NY64 I253T Polymorphism 0.414 0.281 0.05 -11 0.204 Q9NYJ8 P208S Disease 0.551 0.440 0.05 51 0.405 Q9NYJ8 Q230K Disease 0.162 0.265 0.05 29 0.302 Q9NZ01 P182L Disease 0.681 0.883 0.52 32 0.726 Q9NZD1 A18D Polymorphism 0.153 0.450 0.05 20 0.378 Q9NZI5 N191S Polymorphism NA 0.288 0.05 -7 0.225 Q9NZM4 T1044A Polymorphism 0.071 0.180 0.05 2 0.129 Q9P032 L65P Disease 0.317 0.743 0.00 61 0.861 Q9P0N5 G70A Disease NA 0.680 0.00 46 0.627 Q9P0N5 R66C Disease NA 0.852 0.00 62 0.897 Q9P0N5 R66H Disease NA 0.805 0.03 41 0.647 Q9P0N5 R66L Disease NA 0.927 0.03 55 0.899 Q9P0N5 L107R Disease NA 0.828 0.00 66 0.907 Q9P0N8 A54T Polymorphism NA 0.083 0.05 -24 0.079 Q9P1Q0 M912I Polymorphism 0.327 0.273 0.22 27 0.325 Q9P272 C207G Polymorphism 0.141 0.599 0.01 36 0.439 Q9P2A4 R44Q Polymorphism 0.209 0.192 0.76 -2 0.184 Q9P2M7 R479Q Polymorphism NA 0.134 0.59 41 0.203 Q9P2X0 L85S Disease NA 0.392 0.00 42 0.286 Q9UBV7 A186D Disease 0.662 0.851 0.01 60 0.867 Q9UBV7 L206P Disease 0.797 0.944 0.00 37 0.874 Q9UBY5 R231Q Polymorphism 0.116 0.319 0.05 24 0.257 Q9UFB7 A9T Polymorphism NA 0.200 0.58 -7 0.102 Q9UHD9 L235H Polymorphism 0.844 0.732 0.00 22 0.850 Q9UHD9 P497H Disease 0.451 0.444 0.11 30 0.207 Q9UHD9 P497S Disease 0.225 0.238 1.00 13 0.121 Q9UHD9 P506T Disease 0.092 0.469 0.25 -18 0.216 Q9UHD9 P509S Disease 0.101 0.380 0.62 7 0.140 Q9UHD9 P525S Disease 0.104 0.166 0.48 1 0.106 Q9UHE8 H47Q Polymorphism 0.180 0.287 1.00 -8 0.119 Q9UHE8 F169L Polymorphism 0.141 0.304 0.76 -12 0.171 Q9UHR6 A176V Polymorphism 0.231 0.122 NA 5 0.112 Q9UIS9 P401A Polymorphism 0.499 0.123 0.04 5 0.154 Q9UJ70 W38R Polymorphism NA 0.545 0.41 46 0.668 Q9UK11 L60I Polymorphism 0.261 0.627 0.05 31 0.504 Q9UKI8 R121C Polymorphism NA 0.648 0.00 45 0.715 Q9UKM7 E397K Disease 0.706 0.619 0.20 71 0.886 Q9UKM7 R334C Disease 0.972 0.907 0.00 67 0.940 Q9UKY4 A54E Polymorphism NA 0.379 0.97 -41 0.242 Q9UKY4 F717S Disease 0.883 0.884 0.01 20 0.849 Q9UKY4 G246D Disease NA 0.974 0.00 63 0.939 Q9UKY4 G353S Disease NA 0.765 0.36 38 0.627 Q9UKY4 G482V Disease 0.709 0.846 0.01 34 0.791 Q9UKY4 G726E Disease 0.753 0.932 0.00 60 0.938 Q9UKY4 I198N Disease NA 0.720 0.04 -7 0.584 Q9UKY4 R413P Disease 0.936 0.957 0.00 58 0.949 Q9UKY4 T184M Disease NA 0.667 0.22 13 0.477 Q9UKY4 V373F Disease NA 0.925 0.02 37 0.854 Q9UKY4 W748R Disease 0.983 0.724 0.00 65 0.954 Q9UKY4 W748S Disease 0.984 0.717 0.00 59 0.953 Q9UKY4 Y666C Disease 0.989 0.925 0.00 62 0.959 Q9ULC6 V649M Polymorphism 0.732 0.627 0.05 35 0.757 Q9ULK4 P617Q Disease NA 0.707 0.05 31 0.748 Q9ULL0 E852A Polymorphism NA 0.233 NA 23 0.118 Q9ULP9 A515V Disease 0.829 0.720 0.01 25 0.840 Q9ULP9 D147H Disease 0.805 0.500 0.02 51 0.866 Q9ULP9 F251L Disease 0.675 0.560 0.71 6 0.688 Q9UMR2 V149L Polymorphism 0.471 0.412 0.19 2 0.346 Q9UMX6 G157R Disease 0.727 0.579 0.05 26 0.727 Q9UMZ2 A40G Polymorphism NA 0.043 NA -28 0.025 Q9UNI6 A51E Polymorphism 0.335 0.600 0.27 10 0.424 Q9UPP1 F315S Disease 0.506 0.640 0.05 37 0.775 Q9UPP5 H422R Polymorphism NA 0.155 NA 21 0.140 Q9UPY3 S839F Disease 0.375 0.478 0.03 40 0.510 Q9UPY3 L1583R Disease 0.896 0.897 0.01 51 0.930 Q9UQB3 A482T Polymorphism NA 0.345 0.40 -29 0.231 Q9Y236 Y101H Polymorphism NA 0.423 NA 33 0.437 Q9Y2H5 V43I Polymorphism NA 0.084 0.41 -28 0.102 Q9Y2S0 E47K Disease 0.952 0.885 0.00 69 0.952 Q9Y2S0 G52E Disease 0.787 0.882 0.00 59 0.919 Q9Y2S0 G99S Disease 0.290 0.612 0.20 15 0.434 Q9Y2S0 L51R Disease 0.906 0.927 0.00 67 0.944 Q9Y2S0 L82S Disease 0.624 0.492 0.02 34 0.725 Q9Y2S0 R56C Disease 0.931 0.777 0.00 49 0.920 Q9Y2S0 T50I Disease 0.967 0.889 0.00 53 0.965 Q9Y2Y4 R174S Polymorphism NA 0.050 0.76 4 0.025 Q9Y397 P150S Disease 0.940 0.580 0.56 45 0.899 Q9Y397 R148W Disease 0.997 0.874 0.00 52 0.941 Q9Y473 C505R Polymorphism 0.921 0.921 0.05 83 0.979 Q9Y4W6 A694E Disease 0.810 0.836 0.00 45 0.773 Q9Y4W6 E691K Disease 0.499 0.786 0.02 11 0.515 Q9Y4W6 E700K Disease 0.817 0.894 0.01 47 0.848 Q9Y4W6 G671E Disease 0.836 0.891 0.00 62 0.909 Q9Y4W6 G671R Disease 0.889 0.903 0.00 61 0.838 Q9Y4W6 M666R Disease 0.858 0.956 0.00 64 0.919 Q9Y4W6 M666T Disease 0.758 0.934 0.00 52 0.882 Q9Y4W6 M666V Disease 0.531 0.913 0.01 54 0.852 Q9Y4W6 N432T Disease 0.855 0.850 0.01 53 0.813 Q9Y4W6 R702Q Disease 0.558 0.646 0.11 -7 0.422 Q9Y4W6 T654I Disease 0.863 0.805 0.00 42 0.844 Q9Y574 V17L Polymorphism NA 0.270 0.05 -29 0.208 Q9Y5G0 G188S Polymorphism 0.719 0.711 0.05 41 0.663 Q9Y5G7 R248S Polymorphism 0.376 0.427 0.05 12 0.367 Q9Y5H2 F104L Polymorphism 0.530 0.131 0.05 -27 0.161 Q9Y5N5 N34D Polymorphism 0.589 0.070 1.00 -40 0.015 Q9Y5N6 Y232S Disease 0.182 0.616 0.00 46 0.633 Q9Y5U9 L78P Disease 0.367 0.611 0.26 17 0.651 Q9Y5U9 V21G Disease 0.783 0.799 0.00 28 0.845 Q9Y606 R144W Disease 0.997 0.909 0.00 71 0.958 Q9Y698 V143L Disease 0.573 0.669 0.12 -20 0.689 Q9Y6N3 I104T Polymorphism 0.513 0.750 0.02 12 0.738 Q9Y6Q1 T518I Polymorphism 0.377 0.465 0.24 30 0.321